62nd National Congress of the Italian Society of Rheumatology

• Welcome to the 62nd National Congress of the Italian Society of Rheumatology!

  Andrea Doria

  https://doi.org/10.4081/reumatismo.2025.2231

  327

• CO:01:1 | Efficacy and safety of rituximab across the four phenotypes of IgG4-related disease: a European multi-center cohort study of 115 patients Marco Lanzillotta¹, Jens Vikse², Elisabetta Goni³, Veronica Batani¹, Jasmin Mahajne¹, Lorenzo Dagna¹, Emanuel Della Torre¹. | ¹Unit of Immunology, Rheumatology, Allergy, and Rare Disease, IRCCS Ospedale San Raffaele, Milano, Italy; ²Department of Rheumatology, Stavanger University Hospital, Norway; ³Department of Medicine II, University Hospital, Ludwig Maximilian University, Munich, Germany

  Società Italiana di Reumatologia

  https://doi.org/10.4081/reumatismo.2025.1961

  287

• CO:01:2 | BAG3 in systemic sclerosis: possible therapeutic target and biomarker for pulmonary fibrosis Claudia Iannone^1|2, Margot De Marco³, Antonina Minniti¹, Paola Manzo³, Angela D'Ardia³, Antonia Falco³, Liberato Marzullo³, Angela Rosato³, Maria Caterina Turco³, Roberto Caporali^1|2, Nicoletta Del Papa^1|2. | ¹ASST G. Pini-CTO. UOC Clinica Reumatologica, Milano; ²Department of Clinical Sciences and Community Health, University of Milano; ³Department of Medicine, Surgery and Dentistry Schola Medica Salernitana, Baronissi (SA), Italy

  Società Italiana di Reumatologia

  https://doi.org/10.4081/reumatismo.2025.1962

  221

• CO:01:3 | Which PRO reflects remission best? Bridging the gap between patient and physician in systemic lupus erythematosus Elena Ragusa¹, Elisabetta Chessa², Marta Paola Pireddu¹, Fabio Congiu¹, Giulia Rizzo¹, Marianna Salis¹, Alessandra Oliva¹, Mattia Congia², Alberto Cauli^1|2, Matteo Piga^1|2. | ¹SC Reumatologia, Dipartimento di Scienze Mediche e Salute Pubblica, Università di Cagliari; ²SC Reumatologia, AOU Cagliari, Italy

  Società Italiana di Reumatologia

  https://doi.org/10.4081/reumatismo.2025.1963

  206

• CO:01:4 | Identify predictors of relapse in idiopathic inflammatory myopathies: insights from an international cohort Cristina Bochicchio^1|2, Maria Rosa Pellico^1|2, Claudia Iannone^1|2, Lekshmi Minikumari Rahulan³, Marco Fornaro⁴, Ilaria Cavazzana⁵, Edoardo Conticini⁶, Musataka Musataka⁷, Akira Yoshida⁷, Silvia Cavalli^1|2, Silvia Grazzini⁶, Giulio Fraticelli⁸, Alessia Gatti⁵, Giulio Lopinto⁴, Paolo Semeraro⁵, Veronica Batani⁸, Thomas Patric Sheeran⁹, Florenzo Iannone⁴, Giacomo De Luca⁸, Roberto Caporali^1|2, Latika Gupta^9|10|11, Nicoletta Del Papa². | ¹Department of Clinical Sciences and Community Health, University of Milano; ²Department of Rheumatology and Medical Sciences, ASST Gaetano Pini-CTO Institute, Milano, Italy; ³Rheumatology "Sanjay Gandhi" Postgraduate Institute of Medical Sciences, Lucknow, Uttar Pradesh, India; ⁴Unit of Rheumatology, Department of Precision and Regenerative Medicine, Area Jonica, University of Bari; ⁵Rheumatology and Clinical Immunology Unit, ASST Spedali Civili di Brescia; ⁶Rheumatology Unit, Department of Medicine, Surgery and Neurosciences, University of Siena, Italy; ⁷Department of Allergy and Rheumatology Nippon Medical School Graduate School of Medicine, Tokyo, Japan; ⁸Unit of Immunology, Rheumatology, Allergy and Rare Diseases, IRCCS San Raffaele Hospital, Milano, Italy; ⁹Department of Rheumatology, Royal Wolverhampton Hospitals NHS Trust, Wolverhampton, UK; ¹⁰Francis Crick Institute, London, UK; ¹¹School of Infection, Inflammation and Immunology, College of Medicine and Health, University of Birmingham, UK

  Società Italiana di Reumatologia

  https://doi.org/10.4081/reumatismo.2025.1964

  194

• CO:02:1 | Frequency and predictors of disease progression in contemporary seronegative undifferentiated arthritis in a treated-to-target early arthritis clinic Elena Manna¹, Ludovico De Stefano^1|2, Domenico Sorace^1|2, Jacopo Pelizza^1|2, Blerina Xoxi^1|2, Antonio Manzo^1|2, Carlomaurizio Montecucco^1|2, Serena Bugatti^1|2. | ¹Department of Internal Medicine and Therapeutics, University of Pavia; ²Division of Rheumatology, IRCCS Policlinico San Matteo Foundation, Pavia, Italy

  Società Italiana di Reumatologia

  https://doi.org/10.4081/reumatismo.2025.1965

  176

• CO:02:2 | Effectiveness of tumor necrosis factor inhibitors in rheumatoid arthritis: real world data from an Italian National Registry Valerio Fiorilli¹, Francesca Romana Spinelli¹, Florenzo Iannone², Chiara Bazzani³, Alberto Cauli⁴, Rosario Foti⁵, Marcello Govoni⁶, Francesco Paolo Cantatore⁷, Fabiola Atzeni⁸, Roberto Caporali⁹, Marco Sebastiani¹⁰, Roberta Ramonda¹¹, Serena Bugatti¹², Elisa Gremese¹³, Maria Sole Chimenti¹⁴, Bruno Frediani¹⁵, Maurizio Rossini¹⁶, Angelo Semeraro¹⁷, Leonardo Santo¹⁸, Gianfranco Ferraccioli¹⁹, Giovanni Lapadula²⁰, Fabrizio Conti¹. | ¹Dipartimento di Scienze Cliniche Internistiche, Anestesiologiche e Cardiovascolari, Sapienza Università di Roma; ²Dipartimento di Medicina di Precisione e Rigenerativa e Area Jonica, Università degli Studi Aldo Moro, Bari; ³ASST Spedali Civili di Brescia, Unità di Reumatologia ed Immunologia Clinica, Brescia; ⁴Dipartimento di Scienze Mediche e Sanità Pubblica, Università degli Studi di Cagliari; ⁵A.O.U. Policlinico S. Marco, UOS Reumatologia, Catania; ⁶Dipartimento di Scienze Mediche, Università di Ferrara; ⁷Unità di Reumatologia,  Dipartimento di Medicina Specialistica, Università di Foggia; ⁸Dipartimento di Medicina Interna e Terapia Medica, UOC di Reumatologia, Università di Messina; ⁹Dipartimento di Scienze Cliniche e di Comunità, Università di Milano; ¹⁰Dipartimento di Medicina e Chirurgia, Università di Parma; ¹¹Unità di Reumatologia, Dipartimento di Medicina, Università di Padova; ¹²Dipartimento di Medicina Interna e Terapia Medica, Università di Pavia, ; ¹³IRCCS Istituto Clinico Humanitas, Dipartimento di Scienze Biomediche, Milano; ¹⁴Dipartimento di Medicina dei Sistemi, Università degli Studi di Roma-Tor Vergata, ; ¹⁵Dipartimento di Medicina Clinica e Scienze Immunologiche, Università di Siena; ¹⁶Dipartimento di Medicina, Università di Verona; ¹⁷Presidio Ospedaliero Valle d'Itria, Unità Operativa di Reumatologia, Martina Franca; ¹⁸Presidio Ospedaliero "Mons. Dimiccoli", Unità Operativa Semplice di Reumatologia, Barletta; ¹⁹Gruppo Italiano di Studio sulla Early Arthritis, GISEA, Roma; ²⁰Gruppo Italiano di Studio sulla early Arthritis, GISEA, Bari, Italy.

  Società Italiana di Reumatologia

  https://doi.org/10.4081/reumatismo.2025.1966

  178

• CO:02:4 | Whole blood hypercoagulable profiles in patients with rheumatoid arthritis Lorenzo Di Luozzo¹, Alessandro Giollo¹, Mariangela Salvato¹, Francesca Frizzera¹, Kiren Khalid¹, Luca Spiezia², Andrea Benetti², Chiara Samà², Paolo Simioni², Andrea Doria¹. | ^1Unità di Reumatologia, Azienda Ospedaliera di Padova; ²Dipartimento di Medicina, Università di Padova, Italy

  Società Italiana di Reumatologia

  https://doi.org/10.4081/reumatismo.2025.1967

  193

• CO:03:1 | Distinct breath metabolomic signature in systemic sclerosis patients with pulmonary arterial hypertension Martina Iacubino¹, Lorenzo Rocco¹, Marco Vicenzi^2|3, Chiara Bellocchi^2|4, Marta Mozzo⁴, Adriana Severino³, Monica Caronni³, Alessandro Santaniello³, Gaia Montanelli³, Barbara Vigone³, Liam Grimmett⁵, Matthew Kerr⁵, Lorenzo Beretta³. | ¹Scuola di specializzazione in Allergologia e Immunologia clinica, Università degli Studi di Milano; ²Dipartimento di Scienze Cliniche e Salute di Comunità, Dipartimento di Eccellenza 2023-2027, Università degli Studi di Milano; ³Dipartimento di Malattie Cardio-Toraciche-Vascolari, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milano; ⁴Dipartimento di Immunologia Clinica e Medicina Interna, Scleroderma Unit - Fondazione IRCCS Ca' Granda Ospedale Maggiore, Milano, Italy; ⁵Owlstone Medical, Cambridge, UK

  Società Italiana di Reumatologia

  https://doi.org/10.4081/reumatismo.2025.1968

  198

• CO:03:3 | Contribution of mitochondrial DNA to the onset and maintenance of inflammation in Systemic Sclerosis patients Martina Orlandi¹, Giorgia Sinigaglia², Amelia Spinella¹, Isabella Martusciello², Marco De Pinto¹, Giorgia Roveta¹, Luca Keller¹, Marcello Pinti², Dilia Giuggioli¹ | ¹Dipartimento di scienze mediche e chirurgiche dei bambini e degli adulti, Università di Modena e Reggio Emilia, Italy; ²Università degli Studi di Modena e Reggio Emilia, Italy

  Società Italiana di Reumatologia

  https://doi.org/10.4081/reumatismo.2025.2274

  35

• CO:04:1 | Bone properties and biomechanics in patients with psoriatic disease: a cross-sectional study with high-resolution peripheral quantitative computed tomography Anna Piccinelli¹, Francesco Bellinato², Francesco Pollastri¹, Francesco Giorgio¹, Martina Teoni¹, Angelo Fassio¹, Camilla Benini¹, Carmela Dartizio¹, Mattia Tugnolli¹, Davide Gatti¹, Maurizio Rossini¹, Ombretta Viapiana¹, Paolo Gisondi², Giovanni Adami¹. | ¹Rheumatology Unit, University of Verona; ²Dermatology Unit, University of Verona, Italy

  Società Italiana di Reumatologia

  https://doi.org/10.4081/reumatismo.2025.1969

  179

• CO:05:1 | Predicting one-year disease activity in systemic lupus erythematosus using machine learning and explainable AI Pier Giacomo Cerasuolo¹, Augusta Ortolan¹, Livia Lilli², Laura Antenucci², Carlotta Maschiocchi², Jacopo Lenkowicz², Lucia Lanzo¹, Luca Petricca¹, Maria Rita Gigante¹, Vivianaantonella Pacucci¹, Pierluigi Rizzuti¹, Rebecca Ventura¹, Silvia Piunno¹, Cesare Gavotti¹, Marco Gorini³, Gabriella Castellino³, Alfredo Cesario², Stefano Patarnello², Silvia Laura Bosello¹, Maria Antonietta D'Agostino¹. | ¹UOC di Reumatologia ed Immunologia Clinica, Fondazione Policlinico A. Gemelli IRCCS, Università Cattolica del Sacro Cuore, Roma; ²Gemelli Generator, Fondazione Policlinico Universitario Agostino Gemelli IRCCS, Roma; ³AstraZeneca Italy, MIND, Milano, Italy

  Società Italiana di Reumatologia

  https://doi.org/10.4081/reumatismo.2025.1970

  190

• CO:05:2 | An OMERACT study for the development of an algorithm for automatic identification of calcium pyrophosphate deposition by ultrasound: the Crystal Artificial Intelligence Monitoring Study Daniele Cirillo¹, Tito Bassani², Silvia Sirotti^1|2, Greta Pellegrino^1|2, Alessandro Lucia¹, Rodolfo Fabbri¹, Laura Pezzoni¹, Piercarlo Sarzi Puttini^1|2, Georgios Filippou^1|2. | ¹Università degli Studi di Milano; ²IRCCS Ospedale Galeazzi - Sant'Ambrogio, Milano, Italy

  Società Italiana di Reumatologia

  https://doi.org/10.4081/reumatismo.2025.1971

  189

• CO:05:3 | Radiomics and machine learning for differentiating rheumatoid arthritis-associated interstitial lung disease and idiopathic pulmonary fibrosis with usual interstitial pneumonia pattern Vincenzo Venerito¹, Chiara Nani², Andreina Manfredi³, Marco Fornaro¹, Giuseppe Lopalco¹, Florenzo Iannone¹, Cecilia Burattini², Marco Sebastiani⁴. | ¹Rheumatology Unit, University of Bari; ²Respiratory Unit, Guglielmo da Saliceto Civil Hospital, Piacenza; ³Rheumatology Unit, Azienda Unità Sanitaria Locale-IRCCS di Reggio Emilia; ⁴Rheumatology Unit, AUSL Piacenza, University of Parma, Italy

  Società Italiana di Reumatologia

  https://doi.org/10.4081/reumatismo.2025.1972

  190

• CO:05:4 | Natural language processing reveals demographic features, comorbidities, and clinical domains to predict treatment longevity of b/tsDMARDs in psoriatic arthritis Antonio Tonutti^1|2, Pierandrea Morandini³, Cosimo Faeti³, Nicoletta Luciano^1|2, Saverio D'Amico³, Victor Savevski³, Carlo Selmi^1|2 | ¹Department of Biomedical Sciences, Humanitas University Pieve Emanuele, Milan, Italy; ²Rheumatology and Clinical Immunology, IRCCS Humanitas Research Hospital Rozzano, Milan, Italy; ³Artificial Intelligence Unit, IRCCS Humanitas Research Hospital Rozzano, Milan, Italy

  Società Italiana di Reumatologia

  https://doi.org/10.4081/reumatismo.2025.2275

  23

• CO:06:1 | Predictors of damage accrual in a monocentric cohort of patients with Behçet’s syndrome (BS) evaluated with BS overall damage index in real-life clinical practice Giulia Voltarel^1|2, Francesca Crisafulli^1|2, Alba Chiara Pozzi^1|2, Anita Melzani², Micol Frassi¹, Ilaria Cavazzana^1|2, Franco Franceschini^1|2, Paolo Airò¹. | ¹Rheumatology and Clinical Immunology Unit - ERN ReCONNET, ASST Spedali Civili of Brescia; ²Department of Clinical and Experimental Sciences, University of Brescia, Italy

  Società Italiana di Reumatologia

  https://doi.org/10.4081/reumatismo.2025.1973

  159

• CO:06:2 | Deep immunophenotyping in patients with juvenile localized scleroderma reveals two distinct immunological endophenotypes Emiliano Marasco¹, Angela Aquilani¹, Rebecca Nicolai¹, Ivan Caiello¹, Fabrizio De Benedetti¹. | ¹Unità di Reumatologia, Ospdeale Pediatrico Bambino Gesù, Roma, Italy

  Società Italiana di Reumatologia

  https://doi.org/10.4081/reumatismo.2025.1974

  157

• CO:06:3 | Clinical and laboratory markers for distinguishing VEXAS from Schnitzler's syndrome in male patients with skin involvement: insights from the International AIDA Network Registries Valeria Caggiano¹, Jessica Sbalchiero¹, Micol Frassi², Andrea Hinojosa-Azaola³, Francesca Crisafulli², Franco Franceschini², Paolo Sfriso⁴, Sara Bindoli⁴, José Hernández-Rodríguez⁵, Henrique A. Mayrink Giardini⁶, Giuseppe Lopalco⁷, Florenzo Iannone⁷, Ombretta Viapiana⁸, Amato De Paulis⁹, Lorenzo Dagna¹⁰, Antonio Gidaro¹¹, Serena Bugatti¹², Matteo Piga¹³, Fabrizio Conti¹⁴, Rosetta Vitetta¹⁵, Cecilia Chighizola¹⁶, Marcello Govoni¹⁷, Giacomo Emmi¹⁸, Paola Triggianese¹⁹, Carmelo Gurnari¹⁹, Bruno Frediani¹, Claudia Fabiani¹, Luca Cantarini¹, Antonio Vitale¹, for the AIDA Network¹ | ¹Department of Medical Sciences, Surgery and Neurosciences, University of Siena; ²University of Brescia, Italy; ³Department of Immunology and Rheumatology, Mexico City, Mexico; ⁴Rheumatology Unit, University of Padova, Italy; ⁵Clinical Unit of Autoinflammatory Diseases, Hospital Clínic of Barcelona, Spain; ⁶Rheumatology Division, Universidade de São Paulo, Brazil; ⁷University of Bari; ⁸Rheumatology Unit, University and Azienda Ospedaliera Universitaria Integrata of Verona; ⁹University of Napoli "Federico II"; ¹⁰Università Vita-Salute San Raffaele, Milano; ¹¹Luigi Sacco Hospital, University of Milano; ¹²Università di Pavia; ¹³University and AOU of Cagliari; ¹⁴AOU Policlinico Umberto I, Sapienza University of Rome; ¹⁵Unit of Rheumatology, ASL Sant' Andrea Hospital, Vercelli; ¹⁶University of Milano; ¹⁷Azienda Ospedaliero-Universitaria S. Anna, Ferrara; ¹⁸University of Trieste; ¹⁹University of Rome-Tor Vergata, Rome, Italy.

  Società Italiana di Reumatologia

  https://doi.org/10.4081/reumatismo.2025.1975

  198

• CO:07:1 | Assessing bone fragility in systemic sclerosis: results of the Sclerobone multicentric study Giammarco De Mattia¹, Cristina Di Nicola², Davide Rozza², Manuel Sette³, Veronica Gerli³, Ludovica Pisapia¹, Chiara Sgorbini¹, Giulia Botticella⁴, Pamela Bernardini⁵, Francesca Bottazzi⁶, Francesca Lalli⁸, Luca Idolazzi⁷, Laura Bogliolo⁶, Monica Cesarotti⁸, Alessandra Rossi¹, Alessandra Della Rossa¹, Andrea Giusti⁴, Serena Guiducci⁵, Carlo Alberto Scirè², Addolorata Corrado⁹, Nicoletta Del Papa³, Marta Mosca¹, Chiara Crotti³, Maurizio Rossini⁷, Maurizio Mazzantini¹. | ¹UO Reumatologia, Dipartimento di Specialità Mediche e Chirurgiche, Azienda Ospedaliero-Universitaria Pisana, Pisa; ²Centro Studi SIR, Società Italiana di Reumatologia, Milano; ³UO Reumatologia, ASST Gaetano Pini-CTO, Milano; ⁴SC Reumatologia, Ospedale La Colletta, Azienda Sanitaria Locale 3 Liguria, Arenzano (GE); ⁵SOD Reumatologia, Azienda Ospedaliero-Universitaria Careggi, Firenze; ⁶SC Reumatologia, Fondazione IRCCS Policlinico San Matteo, Pavia; ⁷UOC Reumatologia, Azienda Ospedaliera Universitaria Integrata di Verona; ⁸SSD Reumatologia, Azienda Sanitaria Locale Perugia; ⁹Clinica Reumatologica Universitaria, Azienda Ospedaliero Universitaria di Foggia, Italy

  Società Italiana di Reumatologia

  https://doi.org/10.4081/reumatismo.2025.1976

  200

• CO:07:2 | Quantitative computed tomography analysis of pulmonary disease in systemic sclerosis: correlation between radiomics and pulmonary function tests Francesco Pollastri¹, Loredana Carobene², Giovanni Adami¹, Michele Pernigotto³, Federico Aldegheri¹, Angela Ventura³, Claudio Micheletto², Susanna Baltieri³, Marco Sebastiani^4|6, Andreina Manfredi⁵, Davide Gatti¹, Maurizio Rossini¹, Angelo Fassio¹. | ¹UOC Reumatologia, Università degli Studi di Verona; ²UOC Pneumologia, Università degli Studi di Verona; ³ UOC Radiologia, Università degli Studi di Verona; ⁴Universita degli Studi di Parma; ⁵UUOC Reumatologia, Università degli Studi di Modena e Reggio Emilia; ⁶UOC Reumatologia, Azienda Unita' Sanitaria Locale, Piacenza, Italy

  Società Italiana di Reumatologia

  https://doi.org/10.4081/reumatismo.2025.1977

  164

• CO:07:3 | Does articular and entheseal structural damage drive pain and patient-driven reported outcomes in difficult-to-treat psoriatic arthrtis patients? Results from a cross-sectional study Fabio Massimo Perrotta¹, Alen Zabotti², Mauro Fatica¹, Nicola Cabas², Andrea Guiotto², Nicoletta Franzolini³, Giovanni Striani², Maria De Martino⁴, Cristina De Nicola⁵, Miriam Isola⁴, Andrea Di Matteo⁶, Gabriele De Marco⁶, Denis McGonagle⁶, Ennio Lubrano¹, Luca Quartuccio⁴. | ¹Università degli studi del Molise, Campobasso; ²University Hospital Santa Maria della Misericordia, Udine; ³Presidio Ospedaliero S. Antonio, San Daniele del Friuli (UD); ⁴University of Udine; ⁵Epidemiology Unit, Italian Society for Rheumatology, Milano, Italy; ⁶University of Leeds, Leeds, UK

  Società Italiana di Reumatologia

  https://doi.org/10.4081/reumatismo.2025.1978

  138

• CO:07:4 | Clinical and psychosocial domains in fibromyalgia: a multidimensional questionnaire approach for personalized management. Results from an Italian monocentric study Eleonora Pedretti¹, Francesca Regola¹, Giulia Fontana^1|2, Giulia Voltarel^1|2, Michela Riolfo^1|2, Anna Scalvini¹, Ilaria Cavazzana^1|2, Franco Franceschini^1|2, Roberto Gorla¹. | ¹Rheumatology and Clinical Immunology Unit - ERN ReCONNET, ASST Spedali Civili of Brescia; ²Department of Clinical and Experimental Sciences, University of Brescia, Italy

  Società Italiana di Reumatologia

  https://doi.org/10.4081/reumatismo.2025.1979

  193

• CO:07:5 | Enhanced fibroblast signatures in females with early rheumatoid arthritis highlights a potential basis for poorer treatment outcomes Benedetta Monosi¹, James Perera², Alessandra Nerviani^2|3, Maria Sole Chimenti¹, Felice Rivellese^2|3, Costantino Pitzalis^2|3|4. | ¹Rheumatology, Allergology and Clinical Immunology, Department of Systems Medicine, University of Rome Tor Vergata, Rome, Italy; ²Centre for Experimental Medicine and Rheumatology, William Harvey Research Institute, Queen Mary University of London, London, UK; ³Barts Health NHS Trust and Barts Biomedical Research Centre, National Institute for Health and Care Research, London, UK; ⁴Department of Biomedical Sciences Humanitas University and IRCCS Humanitas Research Hospital, Milano, Italy

  Società Italiana di Reumatologia

  https://doi.org/10.4081/reumatismo.2025.1980

  167

• CO:07:6 | Hidden in plain sight: fibromyalgia prevalence and correlates in 3,000 non-clinical Italian subjects Sergio Del Vescovo¹, Vincenzo Venerito¹, Maria Giannotta¹, Maria Grazia Anelli¹, Maria Morrone¹, Angelo Troiano¹, Marco Capodiferro¹, Marco Fornaro¹, Giuseppe Lopalco¹, Florenzo Iannone¹. | ¹UOC Reumatologia, DiMePre-J, Policlinico di Bari, Italy

  Società Italiana di Reumatologia

  https://doi.org/10.4081/reumatismo.2025.1981

  149

• CO:08:1 | Aquaporin-4 downregulation in dysphagic idiopathic inflammatory myopathies: association with Type 2 fiber damage and inflammation Marco Fornaro¹, Margherita Giannini², Dario D'Abbicco³, Maria Luisa Fiorella⁴, Antonio Frigeri⁵, Francesco Girolamo⁶, Florenzo Iannone¹. | ¹Unit of Rheumatology, Department of Precision and Regenerative Medicine and Ionian Area, Bari, Italy; ²Physiologie et Explorations Fonctionnelles Musculaires, University Hospital of Strasbourg, Strasburgo, France; ³Institute of General Surgery G Marinaccio, Department of Precision and Regenerative Medicine and Ionian Area, Bari; ⁴Unit of Otolaryngology, Department of Translational Biomedicine and Neuroscience DiBraiN, Bari; ⁵Unit of Human Physiology, Department of Translational Biomedicine and Neuroscience DiBraiN, Bari; ⁶Unit of Human Anatomy and Histology, Department of Translational Biomedicine and Neuroscience DiBraiN, Bari, Italy

  Società Italiana di Reumatologia

  https://doi.org/10.4081/reumatismo.2025.1982

  134

• CO:08:2 | Impact of comorbidities on clinical-serological phenotype of primary Sjögren's disease: a retrospective analysis of a multicenter cohort Roberto Dal Pozzolo¹, Maria Letizia Currò², Giacomo Cafaro¹, Valeria Manfrè³, Gaetano La Rocca⁴, Alessia Alunno⁵, Francesco Carubbi⁵, Nicoletta Del Papa⁶, Viktoriya Pavlych⁷, Ilenia Fischetti⁸, Letizia Pia Di Corcia⁹, Pamela Bernardini¹⁰, Luca Quartuccio³, Chiara Baldini⁴, Paola Cipriani⁷, Roberta Priori⁸, Onorina Berardicurti⁹, Serena Guiducci¹⁰, Serena ColaFrancesco¹¹, Fabiola Atzeni², Elena Bartoloni¹. | ¹SC Reumatologia. Università di Perugia; ²Unità di Reumatologia. Università di Messina; ³Unità di Reumatologia, Università di Udine; ⁴Unità di Reumatologia. Università di Pisa; ⁵Divisione di Medicina Interna e Nefrologia. Università di L'Aquila; ⁶Dipartimento di Reumatologia. Università di Milano; ⁷Unità di Reumatologia, Università di L'Aquila; ⁸UOC Reumatologia. Università Sapienza, Roma; ⁹Unità di Reumatologia. Università Campus Biomedico, Roma; ¹⁰Unità di Reumatologia. Università di Firenze; ¹¹Reumatologia e Immunologia Clinica. IRCCS Humanitas, Milano, Italy

  Società Italiana di Reumatologia

  https://doi.org/10.4081/reumatismo.2025.1983

  128

• CO:08:4 | Paraproteinemias in Sjögren’s disease: cryoglobulinemia and monoclonal component define distinct phenotypes with a synergistic lymphoproliferative risk Maria Teresa Rizzo¹, Simone Longhino¹, Giacomo Cafaro², Valeria Manfrè¹, Francesco Carubbi³, Alessia Alunno³, Piera Altieri³, Nicoletta Del Papa⁴, Paola Cipriani⁵, Fabiola Atzeni⁶, Francesca Cracò⁶, Onorina Berardicurti⁷, Andrea Pilato⁷, Roberta Priori⁸, Angelica Gattamelata⁸, Serena Guiducci⁹, Chiara Baldini¹⁰, Beatrice Dei¹⁰, Pamela Bernardini⁹, Elena Bartoloni², Luca Quartuccio¹ | ¹Clinica di Reumatologia, Ospedale Santa Maria della Misericordia, Azienda Sanitaria Universitaria Friuli Centrale AS Udine; ²SC Reumatologia, Dipartimento di Medicina e Chirurgia, Università di Perugia; ³Unità operativa di Medicina Interna e Nefrologia, Dipartimento delle Scienze della Vita, della Salute e dell Ambiente L'Aquila; ⁴Unità operativa di Sclerodermia, Dipartimento di Reumatologia, ASST G. Pini-CTO, Università degli Studi di Milano; ⁵Unità operativa di Reumatologia, Dipartimento di Scienze Cliniche Applicate e Biotecnologiche, Università dell'Aquila; ⁶UOC di Reumatologia, Dipartimento di Medicina Interna e Sperimentale, Università di Messina; ⁷UOC di Immuno-Reumatologia, Dipartimento di Medicina e Chirurgia, Università Campus Bio-Medico di Roma; ⁸UOC Reumatologia, Sapienza Università di Roma; ⁹SOD Reumatologia, Dipartimento di Medicina Sperimentale e Clinica, Università degli Studi di Firenze; ¹⁰Clinica di Reumatologia, Dipartimento di Medicina Clinica e Sperimentale, Università di Pisa, Italy

  Società Italiana di Reumatologia

  https://doi.org/10.4081/reumatismo.2025.2119

  137

• CO:08:5 | Clinical impact of anti-Ro52 antibodies in idiopathic inflammatory myopathies: insights from a multicenter Italian cohort Paola Bizioli¹, Cesare Tomasi², Francesca Bellisai³, Francesca Buzzulini⁴, Antonio Tonutti^5|6, Angela Ceribelli^5|6, Edoardo Conticini³, Anna Ghirardello⁷, Luca Iaccarino⁷, Danilo Villalta⁴, Franco Franceschini¹, Ilaria Cavazzana¹. | ¹Rheumatology and Clinical Immunology Unit - ERN ReCONNET, ASST Spedali Civili of Brescia; ²Department of Clinical and Experimental Sciences, University of Brescia; ³Department of Medicine, Surgery and Neurosciences, Rheumatology Unit, University of Siena; ⁴Department of Laboratory Immunology and Allergology, Santa Maria degli Angeli Hospital, Pordenone; ⁵Department of Biomedical Sciences, Humanitas University, Rozzano (MI); ⁶Rheumatology and Clinical Immunology, Istituti di Ricovero e Cura a Carattere Scientifico, Humanitas Research Hospital, Rozzano (MI); ⁷Division of Rheumatology, Department of Medical and Surgical Sciences, University of Padova, Italy

  Società Italiana di Reumatologia

  https://doi.org/10.4081/reumatismo.2025.1984

  137

• CO:08:6 | Prevalence, incidence and survival in interstitial lung disease secondary to primary Sjögren’s syndrome. Results from the “EMERGE” longitudinal study Alessandra Rai¹, Caterina Vacchi², Stefania Cerri³, Roberta Eufrasia Ledda⁴, Giulia Cassone², Dario Andrisani³, Filippo Gozzi³, Lucia Dardani¹, Fabiola Atzeni⁵, Athina Patsoura³, Francesca Cozzini¹, Marco Sebastiani⁶, Andreina Manfredi¹. | ¹USL-IRCCS Reggio Emilia, University of Modena and Reggio Emilia; ²Azienda Ospedaliero Universitaria Policlinico di Modena; ³ Pulmonology Unit, AOU Policlinico di Modena, University of Modena and Reggio Emilia; ⁴Radiology Unit, Azienda Ospedaliera di Parma, University of Parma; ⁵ Policlinico Gaetano Martino, University of Messina; ⁶Azienda Ospedaliera di Piacenza,University of Parma, Italy

  Società Italiana di Reumatologia

  https://doi.org/10.4081/reumatismo.2025.1985

  149

• CO:09:1 | The impact of sex and gender on fibromyalgia syndrome: data from the Italian Fibromyalgia Registry Martina Favretti¹, Cristina Iannuccelli², Giulio Dolcini¹, Sonia Farah³, Marco Di Carlo³, Giuseppina Tramontano⁴, Giorgia Ferrari⁴, Fabiola Atzeni⁵, Greta Pellegrino^6|7, Piercarlo Sarzi-Puttini^6|7, Fausto Salaffi³, Manuela Di Franco⁸. | ¹Dipartimento di Medicina Molecolare, Sapienza Università di Roma; ²UOC Reumatologia, Policlinico Umberto I, Roma; ³Unità di Reumatologia, Dipartimento di Scienze Cliniche e Molecolari, Università Politecnica delle Marche, Jesi (AN); ⁴Unità di Reumatologia, Dipartimento di Specialità Mediche, Regional Health Trust 3, Genova; ⁵Unità di Reumatologia, Dipartimento di Medicina Interna, Università di Messina; ⁶Unità di Reumatologia, IRCCS Ospedale Galeazzi - Sant'Ambrogio, Milano; ⁷Dipartimento di Scienze Biomediche e Cliniche, Università degli studi di Milano; ⁸UOC Reumatologia, Dipartimento di Scienze Cliniche Internistiche Anestesiologiche e Cardiovascolari, La Sapienza, Roma, Italy

  Società Italiana di Reumatologia

  https://doi.org/10.4081/reumatismo.2025.1986

  160

• CO:09:2 | Mapping Emotional Function in Fibromyalgia: Integrating Alexithymia, Pain Catastrophizing and Self-Compassion Francesca Trunfio¹, Damiano Currado^1|2, Rosa Bruni³, Barbara Biticchi¹, Francesca Saracino¹, Erika Corberi¹, Ludovica Lamberti¹, Annalisa Marino^1|2, Lyubomyra Kun¹, Leonardo Frasca'¹, Sebastiano Lorusso¹, Marta Vomero², Onorina Berardicurti^1|2, Roberto Giacomelli^1|2, Luca Navarini^1|2 | ¹Rheumatology and Clinical Immunology, Department of Medicine, University of Rome Campus Biomedico, School of Medicine, Rome, Italy; ²Clinical and Research Section of Rheumatology and Clinical Immunology, Fondazione Policlinico Campus Biomedico, Rome, Italy; ³Psychiatrist, Psychotherapist, certified Teacher Mindful Self-Compassion Program, contract Professor at University Campu Rome, Italy

  Società Italiana di Reumatologia

  https://doi.org/10.4081/reumatismo.2025.2276

  22

• CO:09:3 | Effectiveness and safety of nintedanib in autoimmune systemic diseases: real life data from an Italian multicentre study (Island group) of the Italian Society of Rheumatology Corrado Campochiaro¹, Paola Conigliaro², Gianluca Sambataro³, Marco Matucci-Cerinic¹, Marco Sebastiani⁴, Gianluca Bajocchi⁵, Angelo Fassio⁶, Elena Treppo⁷, Elisabetta Zanatta⁸, Elena Bartolini⁹, Francesco Ferro¹⁰, Chiara Bazzini¹¹, Nicoletta Del Papa¹², Gemma Lepri¹³, Andrea Lo Monaco¹⁴, Marta Favero¹⁵, Annamaria Iuliano¹⁶, Francesca Li Gobbi¹⁷, Maria Sole Chimenti², Giuseppe Muscato¹⁸, Giacomo De Luca¹, Francesca Cozzini⁴, Lucia Dardani⁵, Francesco Pollastri⁶, Alessandro Gattron⁷, Beatrice Moccaldi⁸, Caterina Antonini⁹, Gaetano La Rocca¹⁰, Ilaria Cavazzana¹¹, Andreina Manfredi^5|19. | ¹IRCCS San Raffaele Hospital, Vita-Salute San Raffaele, Milano; ²U.O.C. Reumatologia Dipartimento di Medicina dei Sistemi Università di Roma-Tor Vergata, Roma; ³Università Kore, Enna; ⁴University of Parma, Azienda Ospedaliera di Piacenza; ⁵UOC Reumatologia, AUSL IRCCS Reggio Emilia; ⁶UOC Reumatologia Università degli Studi di Verona; ⁷Dipartimento di Medicina, Clinica di Reumatologia, Università degli Studi di Udine; ⁸UOC Reumatologia, Dipartimento di Medicina DIMED, Azienda Ospedale Università di Padova; ⁹SC Interaziendale di Reumatologia, Dipartimento di Medicina e Chirurgia, Università di Perugia, Azienda Integrata Università; ¹⁰Dipartimento di Medicina Clinica e Sperimentale UO Reumatologia-Universitaria AOU Pisa; ¹¹U.O. Reumatologia e Immunologia Clinica ASST Spedali Civili di Brescia; ¹²Clinica Reumatologica, Milano; ¹³S.O.D. di Reumatologia AOU Careggi, Firenze; ¹⁴UOC Reumatologia Azienda Ospedaliero-Universitaria Sant'Anna, Ferrara; ¹⁵Internal Medicine I, Department of Medicine, Ca' Foncello Hospital, AULSS2 Marca Trevigiana, Treviso; ¹⁶UOC Reumatologia, AO San Camillo Forlanini, Roma; ¹⁷Rheumatology Unit, S.Giovanni di Dio Hospital, Firenze; ¹⁸Department of Clinical and Experimental Medicine, Regional Referral Center for Rare Lung Disease, Policlinico, Catania; ¹⁹Università degli Studi di Modena e Reggio Emilia, Italy

  Società Italiana di Reumatologia

  https://doi.org/10.4081/reumatismo.2025.1987

  127

• CO:09:4 | Erosive hand osteoarthritis: the impact of comorbidities in the context of joint disease Sara Bindoli¹, Clarissa Benvoluti¹, Giacomo Cozzi¹, Marta Favero¹, Mariagrazia Lorenzin¹, Andrea Doria¹, Paolo Sfriso¹, Roberta Ramonda¹. | ¹UOC Reumatologia, Dipartimento di Medicina , Università degli studi di Padova, Italy

  Società Italiana di Reumatologia

  https://doi.org/10.4081/reumatismo.2025.1988

  146

• CO:09:5 | LDL-cholesterol goal attainment with ezetimibe and bempedoic acid in patients with rheumatoid arthritis: a simulation study in the Italian CORDIS cohort Alessandro Giollo¹, Kiren Khalid¹, Luca Bonanni², Nicola Ferri³, Gianluca Erre⁴, Matteo Piga⁵, Elena Bartoloni⁶, Andreina Manfredi⁷, Enno Giulio Favalli⁸, Maria Sole Chimenti⁹, Serena Guiducci¹⁰, Eleonora Celletti¹¹, Addolorata Corrado¹², Simone Parisi²⁰, Ivan Giovannini¹³, Elisa Gremese¹⁴, Garifallia Sakellariou¹⁵, Ombretta Viapiana¹⁶, Marco Fornaro¹⁹, Fabiola Atzeni¹⁷, Francesca Romana Spinelli¹⁸, Fabio Cacciapaglia¹⁹ | ¹Università di Padova Padova, Italy; ²UO Medicina Interna ULSS3 Mestre, Italy; ³Università di Padova, Department of Pharmaceutical and Pharmacological Sciences, University of Padova Padova, Italy; ⁴Università di Sassari Sassari, Italy; ⁵Università di Cagliari Cagliari, Italy; ⁶Univeristà degli studi di Perugia Perugia, Italy; ⁷Università di Modena e Reggio Emilia, UO di Reumatologia Ospedale Policlinico di Modena Reggio Emilia, Italy; ⁸IRCCS Humanitas Research Hospital, Rozzano Milano, Italy; ⁹Università Tor Vergata Roma, Italy; ¹⁰Università di Firenze Firenze, Italy; ¹¹Ospedale SS. Annunziata Chieti, Italy; ¹²Università degli studi di Foggia Foggia, Italy; ¹³Università di Udine, Clinica di Reumatologia Udine, Italy; ¹⁴Università degli studi di Milano Milano, Italy; ¹⁵Università degli Studi di Pavia Pavia, Italy; ¹⁶Università di Verona Verona, Italy; ¹⁷Università degli Studi di Messina Messina, Italy; ¹⁸Università La Sapienza Roma, Italy; ¹⁹Università di Bari, Reumatologia Universitaria Policlinico di Bari Bari, Italy; ²⁰S.C. di Reumatologia A.O.U. Città della Salute e della Scienza di Torino - Ospedale Molinette Torino, Italy

  Società Italiana di Reumatologia

  https://doi.org/10.4081/reumatismo.2025.2277

  17

• CO:09:6 | Risk of disease flare during pregnancy and postpartum in inflammatory arthritis: association with therapy discontinuation in the prospective P-RHEUM.it study Dina Zucchi¹, Chiara Tani¹, Francesca Crisafulli², Alessia Gatti², Maria Gerosa³, Cecilia Chighizola³, Melissa Padovan⁴, Salvatore D'Angelo⁵, Florenzo Iannone⁶, Maria Sole Chimenti⁷, Claudia Lomater⁸, Francesca Serale⁹, Veronique Ramoni¹⁰, Oscar Epis¹¹, Bernd Raffeiner¹², Ariela Hoxha¹³, Andrea Doria¹⁴, Leonardo Santo¹⁵, Valentina Canti¹⁶, Francesca Bellisai¹⁷, Giovanna Cuomo¹⁸, on behalf of the P-Rheumit Investigators¹⁹, Greta Carrara²⁰, Cristina Di Nicola²⁰, Davide Rozza²⁰, Carlo Alberto Scirè²⁰, Maria Chiara Gerardi¹¹, Angela Tincani², Laura Andreoli², Marta Mosca¹. | ¹Rheumatology Unit, University of Pisa and Azienda Ospedaliero Universitaria Pisana; ²Rheumatology and Clinical Immunology Unit, ASST Spedali Civili, Brescia; ³Clinical Rheumatology Division, ASST Gaetano Pini-CTO and University of Milano; ⁴Rheumatology Unit, Azienda Ospedaliero-Universitaria S. Anna and University of Ferrara; ⁵Rheumatology Department of Lucania - San Carlo Hospital, Potenza; ⁶Rheumatology Unit, DiMePRE-J, University of Bari; ⁷Department of Systems Medicine, Rheumatology, Allergology and Clinical Immunology, University of Rome-Tor Vergata, Roma; ⁸Torino Academic Rheumatology Center, A.O. Mauriziano di Torino, University of Torino; ⁹Rheumatology Unit, ASL CN1 Cuneo; ¹⁰Internal Medicine Department, ASST Lodi - Ospedale Maggiore di Lodi; ¹¹Division of Rheumatology, Multispecialist Medical Department, Grande Ospedale Metropolitano Niguarda, Milano; ¹²Department of Rheumatology, Central Hospital of Bolzano SABES-ASDAA, Bolzano; ¹³General Medicine and Thrombosis and Hemorrhagic Unit, Department of Medicine, University of Padova; ¹⁴Rheumatology Unit, Department of Medicine, University of Padova; ¹⁵Rheumatology Unit, Mons. Dimiccoli Hospital, Barletta; ¹⁶Division of Immunology, Transplantation and Infectious Diseases, IRCCS Ospedale San Raffaele, Milano; ¹⁷Rheumatology Unit, Department of Medicine, Surgery and Neurosciences, University of Siena; ¹⁸Precision Medicine Department, University of Campania L. Vanvitelli, Napoli; ¹⁹The Italian Society for Rheumatology; ²⁰Epidemiology Research Unit of the Italian Society for Rheumatology, Milano, Italy

  Società Italiana di Reumatologia

  https://doi.org/10.4081/reumatismo.2025.1989

  148

• CO:10:1 | High-grade synovitis and histological pathotype distribution in patients with advanced osteoarthritis undergoing joint replacement: a more inflammatory disease than we thought? Jacopo Ciaffi¹, Lorenzo Bianchi¹, Luana Mancarella², Federica Pignatti², Veronica Brusi², Lucia Lisi², Simona Neri², Elisa Assirelli², Alberto Righi³, Marco Gambarotti³, Francesco Ursini¹. | ¹SSD Medicina e Reumatologia, IRCCS Istituto Ortopedico Rizzoli, Alma Mater Studiorum Università di Bologna; ²SSD Medicina e Reumatologia, IRCCS Istituto Ortopedico Rizzoli, Bologna; ³SSD di Anatomia e Istologia Patologica, IRCCS Istituto Ortopedico Rizzoli, Bologna, Italy

  Società Italiana di Reumatologia

  https://doi.org/10.4081/reumatismo.2025.1990

  133

• CO:10:2 | Common variable immunodeficiency patients complicated by autoimmune and inflammatory rheumatic manifestations reveal high frequency of genetic variants potentially linked to inborn errors of immunity Paolo Semeraro¹, Micol Frassi¹, Silvia Clara Giliani², Franco Franceschini¹, Paolo Airò¹. | ¹Rheumatology and Clinical Immunology Unit, ERN ReCONNET, ASST Spedali Civili of Brescia and University of Brescia; ²Medical Genetic Laboratory, ASST Spedali Civili of Brescia and University of Brescia, Italy

  Società Italiana di Reumatologia

  https://doi.org/10.4081/reumatismo.2025.1991

  140

• CO:10:3 | Clinical response to JAK inhibitors or non-TNFi-targeted biologicals according to synovial tissue characteristics in patients with difficult-to-treat rheumatoid arthritis Mariangela Salvato¹, Alessandro Giollo¹, Francesca Frizzera¹, Kiren Khalid¹, Lorenzo Di Luozzo¹, Maria Capita¹, Marianna Tamussin¹, Carlo Garaffoni², Marny Fedrigo³, Annalisa Angelini³, Ettore Silvagni², Andrea Doria¹. | ¹Rheumatology Unit, Department of Medicine - DIMED, University of Padova; ²Rheumatology Unit, Department of Medical Sciences, University of Ferrara and Azienda Ospedaliero-Universitaria S. Anna; ³Cardiovascular Pathology, Department of Cardiac, Thoracic, Vascular Sciences and Public Health, University of Padova, Italy

  Società Italiana di Reumatologia

  https://doi.org/10.4081/reumatismo.2025.1992

  150

• CO:10:4 | Lung vasculature quantification on computed tomography predicts new onset of interstitial lung disease in systemic sclerosis Maria Iacovantuono^1|2, Nicholas Landini^2|3, Lisa Jungblut⁴, Gesa Sauer², Rucsandra Dobrota², Maria Sinziana Muraru-Carbune², Muriel Elhai², Carmen-Marina Mihai², Mike Oliver Becker², Maria Sole Chimenti¹, Thomas Frauenfelder⁴, Anna-Maria Hoffmann-Vold⁵, Oliver Distler², Cosimo Bruni². | ¹Rheumatology, Allergology and Clinical Immunology, Department of Systems Medicine, Tor Vergata University, Rome, Italy; ²Department of Rheumatology, University Hospital Zurich, University of Zurich, Switzerland; ³Department of Radiological Sciences, Oncology and Pathology, Sapienza University, Policlinico Umberto I, Rome, Italy; ⁴Institute for Diagnostic and Interventional Radiology, University Hospital Zurich, University Zurich, Switzerland; ⁵Department of Rheumatology, Oslo University Hospital, Norway

  Società Italiana di Reumatologia

  https://doi.org/10.4081/reumatismo.2025.1993

  140

• CO:10:5 | Beyond major glands: high-resolution ultrasound mapping of labial salivary and lacrimal gland involvement in Sjögren’s disease Giovanni Fulvio¹, Rossana Izzetti², Valentina Donati³, Caterina Porciani⁴, Silvia Fonzetti¹, Gaetano La Rocca¹, Beatrice Dei¹, Francesco Ferro¹, Marta Mosca¹, Chiara Baldini¹. | ¹Rheumatology Unit, Department of Clinical and Experimental Medicine, University of Pisa; ²Unit of Dentist, Department of Surgical, Medical and Molecular Pathology and Critical Care Medicine University of Pisa; ³Azienda Ospedaliero-Universitaria Pisana, Unit of Pathological Anatomy, Pisa; ⁴Immunology and Allergology Unit, Department of Clinical and Experimental Medicine, Pisa, Italy

  Società Italiana di Reumatologia

  https://doi.org/10.4081/reumatismo.2025.1994

  149

• CO:10:6 | Impact of pregnancy on organ damage in systemic lupus erythematosus: a prospective multicenter study Giancarlo Cascarano¹, Greta Hulej², Dina Zucchi¹, Antonia Calligaro², Elena Elefante¹, Luca Iaccarino², Sabrina Gori¹, Margherita Zen², Chiara Tani¹, Andrea Doria², Marta Mosca¹. | ¹Università degli Studi di Pisa; ²Università degli Studi di Padova, Italy

  Società Italiana di Reumatologia

  https://doi.org/10.4081/reumatismo.2025.1995

  140

• CO:11:2 | Systemic lupus erythematosus with major neuropsychiatric involvement treated with anifrolumab: literature review and a case report Giulia Rizzo¹, Fabio Congiu¹, Elisabetta Chessa², Marta Paola Pireddu¹, Elena Ragusa¹, Alessandra Oliva¹, Marianna Salis¹, Alberto Cauli^1|2, Matteo Piga^1|2 | ¹SC Reumatologia, Dipartimento di Scienze Mediche e Salute Pubblica, Università di Cagliari Italy; ²SC Reumatologia, AOU Cagliari Italy

  Società Italiana di Reumatologia

  https://doi.org/10.4081/reumatismo.2025.2120

  219

• CO:11:3 | Belimumab for lupus nephritis patients with poor kidney function: a post-hoc analysis of the bliss-ln trial Giacomo Emmi^1|2, Ersilia Lucenteforte³, Giorgio Limoncella³, Emanuele Chiara^1|2, Marta Calatroni^4|5, Gabriella Moroni^4|5 | ¹Clinical Medicine and Rheumatology Unit, Cattinara University Hospital, Trieste, Italy; ²Department of Medical, Surgical and Health Sciences, University of Trieste, Trieste, Italy; ³Department of Statistics, Informatics and Applications Giuseppe Parenti, University of Florence, Florence, Italy; ⁴Department of Biomedical Sciences, Humanitas University, Pieve Emanuele, Milan, Italy; ⁵Nephrology and Dialysis Division, IRCCS Humanitas Research Hospital, Milan, Italy

  Società Italiana di Reumatologia

  https://doi.org/10.4081/reumatismo.2025.2278

  17

• CO:11:4 | Unveiling frailty in active systemic lupus erythematosus  in the modern era of rheumatology: first real-life use of the SLICC-FI  in a cohort diagnosed after 2000 Angela Elia¹, Dina Zucchi², Michele Moretti¹, Elena Elefante², Chiara Cardelli¹, Linda Carli², Viola Signorini², Chiara Stagnaro², Chiara Tani¹, Marta Mosca¹. | ¹U.O. di Reumatologia, Dipartimento di Medicina Clinica e Sperimentale, Università di Pisa; ²U.O Reumatologia, Azienza Ospedaliero Universitaria Pisana, Pisa, Italy

  Società Italiana di Reumatologia

  https://doi.org/10.4081/reumatismo.2025.1996

  164

• CO:11:5 | Laboratory preliminary results from an open label, prospective, phase ii descriptive pilot trial of belimumab therapy for refractory and/or non criteria manifestations of antiphospholipid syndrome Alice Barinotti¹, Massimo Radin¹, Irene Cecchi¹, Beatrice Ala¹, Chiara Raymondi¹, Elena Rubini¹, Silvia G. Foddai¹, Lois Ira Maniulit Capulong¹, Alessio Conti¹, Alessandro Morotti¹, Dario Roccatello¹, Roberta Fenoglio¹, Savino Sciascia¹. | ¹Università di Torino, Italy.

  Società Italiana di Reumatologia

  https://doi.org/10.4081/reumatismo.2025.1997

  158

• CO:11:6 | Off-therapy remission in systemic lupus erythematosus: the BLys lupus flare index (BLyFI) as a decision tool for immunosuppressive therapy withdrawal in remitted patients Noemi Merra¹, Anna Giorgia Osele¹, Davide Ragno¹, Greta Hulej¹, Zahrà Rahmé¹, Ilenia Anna Gennaio¹, Filippo Vesentini¹, Margherita Zen¹, Luca Iaccarino¹, Andrea Doria¹ | Università degli Studi di Padova, Italy

  Società Italiana di Reumatologia

  https://doi.org/10.4081/reumatismo.2025.2121

  156

• CO:12:1 | Inside the Heterogeneity of Primary Central Nervous System Vasculitis: A single-centre 40-year experience Carlo Salvarani¹, Gene G Hunder², Caterina Giannini², Teresa Jh Christianson², Robert D Brown² | ¹Azienda USL-IRCCS di Reggio Emilia e UNIMORE Reggio Emilia, Italy; ²Mayo Clinic Rochester, USA

  Società Italiana di Reumatologia

  https://doi.org/10.4081/reumatismo.2025.2279

  15

• CO:12:2 | Circulating cell signatures of disease activity in ANCA-associated vasculitis using automated hematologic profiling analysis with Sysmex XN-9000®: preliminary results from a monocentric cohort Federica Davanzo¹, Luca Iorio¹, Veronica Davanzo², Michela Pelloso², Eleonora Fiorin¹, Roberta Prevedello¹, Francesca Tosato², Martina Montagnana³, Roberto Padoan¹, Andrea Doria¹ | ¹Rheumatology Unit, Department of Medicine DIMED, University of Padua Padova, Italy; ²Laboratory Medicine Unit, Biomedical Sciences Department-DSB, University of Padua Padova, Italy; ³Department of Medicine DIMED, University of Padua Padova, Italy

  Società Italiana di Reumatologia

  https://doi.org/10.4081/reumatismo.2025.2280

  14

• CO:12:4 | Predicting 12-month clinical relapse in Takayasu arteritis using ^[18F]FDG PET and convolutional neural networks Alessandro Tomelleri¹, Carolina Bezzi², Sara Resta², Corrado Campochiaro¹, Federico Fallanca², Elena Baldissera¹, Samuele Ghezzo², Nicola Farina¹, Arturo Chiti², Paola Mapelli², Marco Matucci-Cerinic¹, Maria Picchio², Lorenzo Dagna¹. | ¹IRCCS Ospedale San Raffaele, Unità di Immunologia Reumatologia Allergologia e Malattie Rare, Milano; ²IRCCS Ospedale San Raffaele, Unità di Medicina Nucleare, Milano, Italy

  Società Italiana di Reumatologia

  https://doi.org/10.4081/reumatismo.2025.1998

  151

• CO:12:5 | Aortic inflammation and aneurysm risk in giant cell arteritis: a multicenter imaging study Caterina Ricordi¹, Chiara Marvisi¹, Konstanze V. Guggenberger², Rudolf A. Werner³, Pamela Mancuso⁸, Giulia Besutti⁴, Sebastian E. Serfling⁵, Roberto Farì⁴, Matthias Frohlich⁶, Rexhep Durmo⁷, Michael Gernert⁶, Lucia Spaggiari⁴, Annibale Versari⁷, Paolo Giorgi Rossi⁸, Pierpaolo Pattacini⁴, Marc Schmalzing⁶, Carlo Salvarani¹, Thorsten Bley⁹, Francesco Muratore¹. | ¹Rheumatology Unit, AUSL IRCCS di Reggio Emilia and Università di Modena e Reggio Emilia, Italy; ²Department of Diagnostic and Interventional Neuroradiology, University Hospital Wuerzburg, Germany; ³Department of Nuclear Medicine, University of Frankfurt, Germany; ⁴Department of Radiology, AUSL IRCCS di Reggio Emilia, Italy; ⁵Department of Nuclear Medicine, University Hospital Wuerzburg, Germany; ⁶Rheumatology and Clinical Immunology, Department of Internal Medicine II, University Hospital Wuerzburg, Germany; ⁷Nuclear Medicine Unit, AUSL IRCCS di Reggio Emilia, Italy; ⁸Epidemiology Unit, AUSL-IRCCS di Reggio Emilia, Italy; ⁹Department of Diagnostic and Interventional Radiology, University Hospital Wuerzburg, Germany

  Società Italiana di Reumatologia

  https://doi.org/10.4081/reumatismo.2025.1999

  140

• PO:01:001 | Clinical and histopathological features of refractory psoriatic arthritis undergoing ultrasound-guided synovial biopsy: comparison between non-inflammatory and persistent inflammatory profiles Marianna Tamussin¹, Carlo Garaffoni¹, Maria Capita¹, Serena Ceccato¹, Giovanni Lanza², Mariangela Salvato³, Kiren Khalid³, Francesca Frizzera³, Lorenzo Di Luozzo³, Annalisa Angelini⁴, Roberta Ramonda³, Alessandra Bortoluzzi¹, Andrea Doria³, Marcello Govoni¹, Alessadro Giollo³, Ettore Silvagni¹ | ¹Rheumatology Unit, Department of Medical Sciences, University of Ferrara and Azienda Ospedaliero-Universitaria S. Anna Ferrara, Italy; ²Pathology Unit, Department of Translational Medicine, University of Ferrara, Ferrara Ferrara, Italy; ³Rheumatology Unit, Department of Medicine , DIMED, University of Padua Padova, Italy; ⁴Cardiovascular Pathology, Department of Cardiac, Thoracic, Vascular Sciences and Pulic Health, University of Padua, Padova, Italy

  Società Italiana di Reumatologia

  https://doi.org/10.4081/reumatismo.2025.2281

  15

• PO:01:003 | Sex-based differences in 2 years treatment outcomes with b/ts-DMARDs in psoriatic arthritis: from real-world evidence to predictive modeling from the Gruppo Italiano Studio Early Arthritis (GISEA) prospective registry Simone Perniola¹, Florenzo Iannone¹, Francesco Paolo Cantatore², Angelo Semeraro³, Leonardo Santo⁴, Roberto Gorla⁵, Alberto Cauli⁶, Roberto Felice Caporali⁷, Bruno Frediani⁸, Rosario Foti⁹, Fabrizio Conti¹⁰, Marco Sebastiani¹¹, Maria Sole Chimenti¹², Roberta Ramonda¹³, Fabiola Atzeni¹⁴, Maurizio Rossini¹⁵, Serena Bugatti¹⁶, Serena Guiducci¹⁷, Giovanni Lapadula¹, Gianfranco Ferraccioli¹⁸, Francesca Romana Spinelli¹⁰, Elisa Gremese¹⁹. | ¹Rheumatology Unit, DiMePReJ, University of Bari, Bari; ²Rheumatology Unit, Department of Medical and Surgical Sciences, Azienda Ospedaliero-Universitaria Policlinico Riuniti, Foggia; ³Rheumatology Unit, Martina Franca Hospital; ⁴Rheumatology Unit, ASL BT, P.O. Barletta; ⁵Rheumatology and Clinical Immunology Unit, ASST Spedali Civili of Brescia; ⁶Rheumatology Unit, Department of Medical Science and Public Health, University of Cagliari, Monserrato (CA); ⁷Rheumatology Unit, Dipartimento di Reumatologia e Scienze Mediche, ASST PINI-CTO, University of Milano, Milano; ⁸Rheumatology Unit, Azienda Ospedaliero Universitaria Senese, Siena; ⁹Rheumatology Unit, A.O.U. Policlinico S. Marco, Catania; ¹⁰Rheumatology Unit, Department of Clinical Internal, Anesthesiologic and CV Sciences, Sapienza University of Rome, Roma; ¹¹Rheumatology Unit, AUSL Piacenza, University of Parma, Parma; ¹²Rheumatology, Department of Systems Medicine, University of Rome Tor Vergata, Roma; ¹³Rheumatology Unit, DIMED, University of Padua, Padova; ¹⁴Rheumatology Unit, Department of Experimental and Internal Medicine, University of Messina, Messina; ¹⁵Rheumatology Unit, Department of Medicine, University of Verona, Verona; ¹⁶Division of Rheumatology, Dept. of Internal Medicine and Therapy, Fondazione IRCCS Policlinico S. Matteo, University of Pavia, Pavia; ¹⁷Division of Rheumatology, Department of Experimental and Clinical Medicine, University of Firenze, Firenze; ¹⁸Department of Medicine, Catholic University of the Sacred Heart, Fondazione Policlinico Gemelli IRCCS, Roma; ¹⁹Rheumatology and Clinical Immunology, IRCCS Humanitas Research Hospital, Humanitas University, Rozzano (MI), Italy

  Società Italiana di Reumatologia

  https://doi.org/10.4081/reumatismo.2025.2000

  192

• PO:01:004 | Real-world retention of IL-17 inhibitors in psoriatic arthritis: impact of prior IL-17 exposure across multiple treatment lines in the “BIRRA” multicentre cohort Valentino Paci¹, Alarico Ariani², Eleonora Celletti³, Alberto Lo Gullo⁴, Camilla Mazzanti⁵, Valeria Nucera⁶, Natalia Mansueto⁷, Rosalba Caccavale⁸, Patrizia Del Medico⁹, Antonella Farina¹⁰, Palma Scolieri¹¹, Cecilia Giampietro¹², Olga Addimanda¹³, Riccardo Bixio¹⁴, Maddalena Larosa¹⁵, Viviana Ravagnani¹⁶, Federica Lumetti¹⁷, Aldo Biagio Molica Colella¹⁷, Elena Bravi¹⁷, Rosetta Vitetta¹⁷, Bernd Raffeiner¹⁷, Gilda Sandri¹⁸, Rosario Foti¹⁹, Simone Parisi²⁰, Michele Maria Luchetti Gentiloni¹, Gianluca Moroncini¹. | ¹Clinical Medicine, Department of Clinical and Molecular Sciences, Marche Polytechnic University, AOU delle Marche, Ancona, Italy; ²Internal Medicine and Rheumatology Unit, University Hospital of Parma, Parma, Italy; ³Rheumatology Unit, Clinica Medica Institute, Ospedale SS. Annunziata di Chieti, G.d'Annunzio University of Chieti, Chieti, Italy; ⁴Rheumatology Unit, ARNAS Garibaldi di Catania, Catania, Italy; ⁵Center for the Diagnosis and Therapy of Autoimmune Rheumagological Diseases, Ospedale Santa Rosa, ASL Viterbo Viterbo Italy; ⁶Rheumatology Outpatient Unit, ASL Novara, Novara, Italy; ⁷Ambulatori di Reumatologia ASL1 Liguria, Imperia Hospitall Imperia Italy; ⁸Department of Clinical, Anesthesiological and Cardiovascular Sciences, Sapienza University of Rome, Polo Pontino, Roma, Italy; ⁹Rheumatology outpatient clinic - Internal Medicine Unit, Civitanova Marche Hospital, Civitanova Marche, Italy; ¹⁰Internal Medicine Unit, Rheumatology outpatient clinic, Ospedale A. Murri di Fermo, Fermo, Italy; ¹¹Department of Medical Specialties, Nuovo Regina Margherita Hospital, Rome, Roma, Italy; ¹²Rheumatology Outpatient Clinic, Azienda ULSS 6 Euganea, Padova, Padova, Italy; ¹³Rheumatology Unit, Azienda Unità Sanitaria Locale di Bologna -- Policlinico S.Orsola- AOU di Bologna, Bologna, Italy; ¹⁴Rheumatology Unit, IRCCS Sacro Cuore Don Calabria Hospital, Negrar di Valpolicella, Verona, Italy; ¹⁵Division of Rheumatology - Medical Specialties Department, Ospedale La Colletta-Azienda Sanitaria Locale 3, Genova, Italy; ¹⁶Rheumatology Unit, Santa Chiara Hospital APSS Trento Italy; ¹⁷BIRRA - BIologic Retention Rate in chronic Arthritis - study group, Parma, Italy; ¹⁸Rheumatology Unit, University of Modena and Reggio Emilia, Modena, Italy; ¹⁹Rheumatology Unit, Policlinico San Marco Hospital, Catania, Italy; ²⁰Rheumatology Department, Azienda Ospedaliera Universitaria Città della Salute e della Scienza di Torino, Torino, Italy.

  Società Italiana di Reumatologia

  https://doi.org/10.4081/reumatismo.2025.2001

  203

• PO:01:005 | Exploring the relationship between alexithymia, pain perception, and disease burden in a cohort of patients with psoriatic arthritis Michelina Turri¹, Eugenio Capparelli¹, Sergio Del Vescovo², Maria Iacovantuono¹, Benedetta Monosi¹, Giulia Mori¹, Ilaria Cristiano¹, Paola Conigliaro¹, Elisabetta Greco¹, Giuseppe Lopalco², Maria Sole Chimenti¹. | ¹Reumatologia, Allergologia e Immunologia Clinica, Dipartimento di Medicina dei Sistemi, Università di, Roma, Tor Vergata, Roma, Italy; ²Dipartimento di Medicina di Precisione e Rigenerativa e Area Ionica ^DiMePRe-J, Università di Bari, Bari, Italy.

  Società Italiana di Reumatologia

  https://doi.org/10.4081/reumatismo.2025.2002

  166

• PO:01:006 | Increased risk of cancer recurrence or mortality associated with DMARDs? Laura Scagnellato¹, Giacomo Cozzi¹, Mariagrazia Lorenzin¹, Mariangela Salvato¹, Alessandro Giollo¹, Bernd Raffeiner¹, Antonia Calligaro¹, Teresa Del Ross¹, Sara Bindoli¹, Margherita Zen¹, Paolo Sfriso¹, Andrea Doria¹, Roberta Ramonda¹. | ¹UOC Reumatologia, Dipartimento di Medicina dei Sistemi DIMED, Ospedale Università di Padova, Padova, Italy.

  Società Italiana di Reumatologia

  https://doi.org/10.4081/reumatismo.2025.2003

  163

• PO:01:007 | Modulation of cellular senescence in psoriatic arthritis: exploring the potential impact of b/tsDMARDs treatment on telomere length, mtDNA copy number, and oxidative damage Eneida Cela¹, Giada De Benedittis², Arianna D'Antonio¹, Andrea Latini³, Chiara Morgante², Cinzia Cicacci³, Paola Conigliaro¹, Mauro Fatica¹, Giulia Mori¹, Giuseppe Novelli², Paola Borgiani², Maria Sole Chimenti¹. | ¹Rheumatology, Allergology and Clinical Immunology, Department of System Medicine, University of Rome Tor Vergata, Rome, Italy; ²Department of Biomedicine and Prevention, Section of Genetics, University of Rome Tor Vergata, Rome, Italy; ³UniCamillus Saint Camillus International University of Health Sciences, Rome, Italy.

  Società Italiana di Reumatologia

  https://doi.org/10.4081/reumatismo.2025.2004

  158

• PO:01:008 | Active sacroiliitis at magnetic resonance enterography increases the risk of axial spondyloarthritis in Crohn’s disease patients, while greater age and disease duration are protective factors: a monocentric retrospective cohort study Gabriele Amati¹, Gilda Sandri^1|2, Giovanni Ciancio², Benedetta Bongiovanni^1|2, Martina Orlandi^1|2, Ottavio Secchi^1|2, Davide Vaccari³, Annarita Pecchi⁴, Angela Bertani⁵, Maddalena Pecchini⁵, Pietro Torricelli⁴, Antonio Colecchia⁵, Dilia Giuggioli^1|2. | ¹Struttura Complessa di Reumatologia, Azienda Ospedaliero-Universitaria Policlinico di Modena, Modena, Italy; ²Cattedra di Reumatologia, Università degli studi di Modena e Reggio Emilia, Modena, Italy; ³Unità Operativa di Radiologia, Ospedale di Pavullo, AUSL di Modena, Modena, Italy; ⁴Struttura Complessa di Radiologia, Azienda Ospedaliero-Universitaria Policlinico di Modena, Modena, Italy; ⁵Struttura Complessa di Gastroenterologia, Azienda Ospedaliero-Universitaria Policlinico di Modena, Modena, Italy.

  Società Italiana di Reumatologia

  https://doi.org/10.4081/reumatismo.2025.2005

  179

• PO:01:010 | Survival of second-line treatment with TNF inhibitors vs. IL-23 inhibitors after failure of a first TNF inhibitor: a real-life observational study from the Italian multicenter BIRRA cohort in patients with psoriatic arthritis Francesca Ometto¹, Olga Addimanda², Bernd Raffeiner³, Alberto Lo Gullo⁴, Elisa Visalli⁵, Eleonora Celletti⁶, Antonella Farina⁷, Maddalena Larosa⁸, Romina Andracco⁹, Marino Paroli¹⁰, Patrizia Del Medico¹¹, Aldo Biagio Molica Collella¹², Federica Lumetti¹³, Gilda Sandri¹⁴, Marta Priora¹⁵, Aurora Ianiello¹⁶, Elena Bravi¹⁷, Alessandra Bezzi¹⁸, Palma Scolieri¹⁹, Simone Parisi²⁰, Viviana Ravagnani²⁰, Rosetta Vitetta²⁰, Luca Idolazzi²⁰, Riccardo Bixio²⁰, Gianluca Santoboni²⁰, Francesco Girelli²⁰, Alarico Ariani²⁰ | ¹Azienda ULSS 6 Euganea, Padova; ²UOC Interaziendale di Medicina Interna ad Indirizzo Reumatologico, AUSL BO - IRCCS AOU Bologna; ³Unità di Reumatologia, Teaching Hospital of the Paracelsius Medical University, Central Hospital of Bolzano (ASAA-SABES) Bolzano; ⁴UOD Reumatologia, ARNAS Garibaldi Catania; ⁵UO Reumatologia, Policlinico San Marco Hospital Catania; ⁶UOS Reumatologia, Ospedale SS. Annunziata, Università G. d'Annunzio, Chieti; ⁷UOC Medicina Interna- Ambulatorio Reumatologico, Ospedale A. Murri, Fermo; ⁸S.C. Reumatologia, Dipartimento Specialità Mediche, Ospedale La Colletta-Azienda Sanitaria Locale 3 Genova; ⁹Ambulatorio Reumatologia, Ospedale di Imperia; ¹⁰Sapienza Università Polo Pontino, Latina; ¹¹Ambulatorio di Reumatologia, UO Medicina Interna, Civitanova Marche Hospital, Civitanova (MC); ¹²UOSD di Reumatologia, Azienda Ospedaliera Papardo Messina; ¹³Unità di Reumatologia, Azienda USL di Modena e Ospedale Universitario Policlinico di Modena; ¹⁴Unità di Reumatologia, Università di Modena e Reggio Emilia Modena; ¹⁵Ambulatorio e Day Hospital di Reumatologia, ASL CN1, Mondovì (CN); ¹⁶Poliambulatorio specialistico di reumatologia e Day Hospital multidisciplinare di area Medica, ASL Novara; ¹⁷UOSD Reumatologia, Ospedale G. Da Saliceto, Piacenza; ¹⁸UO Medicina Interna e Reumatologia, SS Reumatologia, ASL Romagna, Rimini; ¹⁹UOC Medicina Interna e Reumatologia, Ospedale Nuovo Regina Margherita, Roma; ²⁰Gruppo BIRRA Italy

  Società Italiana di Reumatologia

  https://doi.org/10.4081/reumatismo.2025.2122

  177

• PO:01:011 | Achievement of Remission Defined by Absence of Objective Signs of Inflammation Versus ASDAS ID in Patients with Active Axial Spondyloarthritis Treated with Bimekizumab: 52-Week Results from Two Phase 3 Studies Lianne S Gensler¹, Helena Marzo-Ortega², Vanessa Taieb³, Diana Voiniciuc⁴, Alexander Marten⁵, George Stojan⁶, Mindy Kim⁶, Paolo Marsico⁷, Martin Rudwaleit⁸ | ¹Department of Medicine/Rheumatology, University of California San Francisco, USA; ²NIHR Leeds Biomedical Research Centre, University of Leeds Leeds, United Kingdom; ³UCB Colombes, France; ⁴UCB Slough, United Kingdom; ⁵UCB Monheim am Rhein Germany; ⁶UCB Atlanta, USA; ⁷UCB Milan, Italy; ⁸University of Bielefeld, Klinikum Bielefeld Bielefeld Germany

  Società Italiana di Reumatologia

  https://doi.org/10.4081/reumatismo.2025.2282

  20

• PO:01:014 | Differential inflammatory responses of CD14+ and CD14– synoviocytes in psoriatic arthritis: implications for pathogenesis and targeted therapies Monia Maccaferri¹, Monica Montanari², Francesco Zambianchi^3|4, Carlo Salvarani^1|5, Elisa Pignatti^1|4 | ¹Dipartimento CHIMOMO; ²Dipartimento di Scienze e Vita; ³Dipartimento SMECHIMAI Università di Modena e Reggio Emilia; ⁴Azienda Ospedaliero Universitaria di Modena; ⁵Struttura Complessa di Reumatologia, Azienda Unità Sanitaria Locale di Reggio Emilia-IRCCS, Italy

  Società Italiana di Reumatologia

  https://doi.org/10.4081/reumatismo.2025.2123

  142

• PO:01:015 | Assessment of the impact of the co-occurrence of psoriasis on the clinical and therapeutic pattern of a single-centre cohort of patients with spondyloarthritis associated with chronic inflammatory bowel disease Andrea Pace¹, Marcella Falconi¹, Alberto Floris^1|2, Leonardo Sichi¹, Francesca Onnis³, Lorenzo Meli³, Raffaela Piras³, Nicola Lutzu³, Federica Olla³, Agnese Favale³, Sara Onali³, Massimo Claudio Fantini³, Matteo Piga^1|2, Alberto Cauli^1|2. | ¹SC Reumatologia, Dipartimento di Scienze Mediche e Salute Pubblica, Università di Cagliari, Cagliari, Italy; ²SC Reumatologia, AOU Cagliari, Cagliari, Italy; ³SC Gastroenterologia, AOU Cagliari, Cagliari, Italy.

  Società Italiana di Reumatologia

  https://doi.org/10.4081/reumatismo.2025.2006

  162

• PO:01:015 | Evaluation of the impact of concomitant psoriasis on the clinical and therapeutic pattern of a monocentric cohort of patients affected by spondyloarthritis associated with inflammatory bowel diseases Andrea Pace¹, Marcella Falconi¹, Alberto Floris^1|2, Leonardo Sichi¹, Francesca Onnis³, Lorenzo Meli³, Raffaela Piras³, Nicola Lutzu³, Federica Olla³, Agnese Favale³, Sara Onali³, Massimo Claudio Fantini³, Matteo Piga^1|2, Alberto Cauli^1|2 | ¹SC Reumatologia, Dipartimento di Scienze Mediche e Salute Pubblica, Università di Cagliari; ²SC Reumatologia, AOU Cagliari; ³SC Gastroenterologia, AOU Cagliari, Italy

  Società Italiana di Reumatologia

  https://doi.org/10.4081/reumatismo.2025.2124

  127

• PO:02:016 | Real-world evidence of upadacitinib over two years in Italian patients with axial spondyloarthritis Mariagrazia Lorenzin¹, Giacomo Cozzi¹, Stefano Gentileschi², Michele Maria Luchetti Gentiloni³, Antonio Carletto⁴, Maria Sole Chimenti⁵, Maria Manara⁶, Luca Quartuccio⁷, Rosario Foti⁸, Salvatore D'Angelo⁹, Ariela Hoxha¹⁰, Carlo Selmi¹¹, Bernd Raffeiner¹², Alessandro Giollo¹, Alberto Cauli¹³, Carlo Salvarani¹⁴, Fabiola Atzeni¹⁵, Roberta Ramonda¹, Sir Study Group Spa E Psa Antonio Spadaro¹⁶. | ¹Rheumatology Unit, Department of Medicine DIMED, University of Padova, Padova, Italy; ²Rheumatology Unit, Department of Medicine, Surgery and Neurosciences, University of Siena, Siena, Italy; ³Clinica Medica, Ospedali Riuniti Ancona University Hospital, Ancona; Department of Clinical and Molecular Sciences, Ancona, Italy; ⁴Rheumatology Unit, Department of Medicine, AOUI University of Verona, Verona, Italy; ⁵Rheumatology, allergology and clinical Immunology, Department of Systems Medicine, University of Rome Tor Vergata, Roma, Italy; ⁶Humanitas San Pio X, Milano, Italy; ⁷University of Udine, Academic Hospital Santa Maria della Misericordia, Udine, Italy; ⁸Rheumatology Unit, A.O.U. Policlinico S. Marco, Catania, Italy; ⁹Rheumatology Department of Lucania, San Carlo Hospital of Potenza and Madonna delle Grazie Hospital of Matera, Potenza, Italy; ¹⁰Internal Medicine Unit, Thrombotic and Hemorrhagic Center, Department of Medicine-DIMED, University of Padua, Padova, Italy; ¹¹Department of Rheumatology and Clinical Immunology, IRCCS Humanitas Research Hospital, Rozzano, Milano, Italy; ¹²Department of Rheumatology, Teaching Hospital of the Paracelsius Medical Hospital of Bolzano ASAA-SABES, Bolzano, Italy; ¹³Rheumatology Unit, Department of Medical Sciences, AOU and University of Cagliari, Monserrato, Cagliari, Italy; ¹⁴Department of Rheumatology, Azienda USL-IRCCS di Reggio Emilia and Università di Modena and Reggio Emilia, Reggio Emilia, Italy; ¹⁵Rheumatology Unit, University of Messina, Messina, Italy; ¹⁶Società Italiana di Reumatologia, Milano, Italy.

  Società Italiana di Reumatologia

  https://doi.org/10.4081/reumatismo.2025.2007

  170

• PO:02:017 | Difficult-to-treat psoriatic arthritis: clinical and ultrasonographic predictors in a real-life cohort Federico Favaro¹, Elisa Bellis¹, Claudio Cruciani¹, Gloria Crepaldi¹, Valeria Data¹, Claudia Garulli¹, Claudia Lomater¹, Elena Marucco¹, Marta Saracco¹, Mariele Gatto¹, Annamaria Iagnocco¹. | ¹Academic Rheumatology Centre, Departement of Clinical and Biological Sciences, University of Turin, AO Mauriziano, Torino, Italy.

  Società Italiana di Reumatologia

  https://doi.org/10.4081/reumatismo.2025.2008

  144

• PO:02:018 | After-SECs: clinical predictors of secukinumab retention in psoriatic arthritis patients with inadequate response to anti-tumor necrosis factor therapy Francesco Cristiano¹, Davide Gaspare Patti¹, Valentina Boni¹, Stefano Di Murro¹, Cesare Gavotti¹, Roberta Masnata¹, Giulia Calabrese², Gerlando Natalello², Giusy Peluso², Augusta Ortolan^1|2, Enrico De Lorenzis^1|2, Maria Antonietta D'Agostino^1|2. | ¹Università Cattolica del Sacro Cuore, Roma, Italy; ²Divisione di Reumatologia ed Immunologia clinica, Fondazione Policlinico Universitario A. Gemelli IRCCS, Roma, Italy.

  Società Italiana di Reumatologia

  https://doi.org/10.4081/reumatismo.2025.2009

  147

• PO:02:019 | Incidence of Spondyloarthritis in a Cohort of Italian patients presenting with Acute Non-granulomatous Anterior Uveitis during a five-years follow-up period Alessandra Rai¹, Niccolò Possemato^1|2, Giorgia Citriniti², Filippo Crescentiini², Marianna Oliva², Elena Bolletta³, Pietro Gentile³, Luca De Simone³, Fabrizio Gozzi³, Luca Cimino^1|3, Pierluigi Macchioni², Carlo Salvarani^1|2 | ¹Università di Modena e Reggio Emilia Modena, Italy; ²Unità di Reumatologia, Azienda USL-IRCCS Reggio Emilia, Reggio Emilia, Italy; ³Unità di Immunologia Oculare, Azienda USL-IRCCS Reggio Emilia, Reggio Emilia, Italy

  Società Italiana di Reumatologia

  https://doi.org/10.4081/reumatismo.2025.2283

  22

• PO:02:021 | Sustained Improvements with Bimekizumab in Pain, Morning Stiffness, Fatigue, Physical Function and Health-Related Quality of Life in Patients with Axial Spondyloarthritis: 3-Year Results from Two Phase 3 Studies Victoria Navarro-Compán¹, Uta Kiltz^2|3, Philip J Mease⁴, Maureen Dubreuil⁵, Karl Gaffney⁶, Atul Deodhar⁷, Christine De La Loge⁸, Diana Voiniciuc⁹, Jason Coarse¹⁰, Ilaria Spadafora¹¹, Helena Marzo-Ortega¹² | ¹La Paz University Hospital, IdiPaz, Department of Rheumatology Madrid Spain; ²Ruhr-University Bochum Bochum Germany; ³Rheumazentrum Ruhrgebiet Herne, Germany; ⁴Department of Rheumatology, Swedish Medical Center and Providence St. Joseph Health and University of Washington Seattle, USA; ⁵Boston University School of Medicine, Department of Rheumatology Boston, USA; ⁶Norfolk and Norwich University Hospital NHS Trust, Department of Rheumatology Norfolk, United Kingdom; ⁷Oregon Health and Science University, Division of Arthritis and Rheumatic Diseases Portland, USA; ⁸UCB Brussels, Belgium; ⁹UCB Slough, United Kingdom; ¹⁰UCB Morrisville, USA; ¹¹UCB Milan, Italy; ¹²NIHR Leeds Biomedical Research Centre, University of Leeds Leeds, United Kingdom

  Società Italiana di Reumatologia

  https://doi.org/10.4081/reumatismo.2025.2284

  20

• PO:02:022 | Bimekizumab Maintained Stringent Clinical Responses over 2 Years in Patients with Axial Spondyloarthritis: Results from Two Phase 3 Studies Fabian Proft¹, Désirée Van Der Heijde², Sergio Schwartzman^3|4|5, Joerg Ermann⁶, Alexander Marten⁷, Ute Massow⁷, George Stojan⁸, Vanessa Taieb⁹, Diana Voiniciuc¹⁰, Astrid Van Tubergen¹¹, Victoria Navarro-Compán¹², Simone Angioni¹³, Xenofon Baraliakos¹⁴ | ¹Charité-Universitätsmedizin Berlin; Freie Universität Berlin and Humboldt-Universität zu Berlin, Berlin, Germany; ²Department of Rheumatology, Leiden University Medical Center Leiden, The Netherlands; ³Weill Cornell Medical Center New York, USA; ⁴New York Presbyterian Hospital New York, USA; ⁵Hospital for Special Surgery New York, USA; ⁶Division of Rheumatology, Inflammation and Immunity, Brigham and Women's Hospital and Harvard Medical School Boston, USA; ⁷UCB Monheim am Rhein Germany; ⁸UCB Atlanta, USA; ⁹UCB Colombes, France; ¹⁰UCB Slough, United Kingdom; ¹¹Department of Medicine, Division of Rheumatology, Maastricht University Medical Center Maastricht, The Netherlands; ¹²Department of Rheumatology, La Paz University Hospital, IdiPaz Madrid, Spain; ¹³UCB Milan, Italy; ¹⁴Rheumazentrum Ruhrgebiet Herne, Ruhr-University Bochum, Germany

  Società Italiana di Reumatologia

  https://doi.org/10.4081/reumatismo.2025.2285

  20

• PO:02:023 | Monocentric analysis of systemic glucocorticoids in PsA: the art of balancing prescriptive appropriateness and risk factor management Chiara Crotti^{1 2}, Gilberto Cincinelli¹, Giorgia Trignani¹³, Luca Ingrao¹³, Miriam Perino¹³, Roberto Caporali¹³ | ¹Dipartimento di Reumatologia e Scienze Mediche - UOC Clinica Reumatologica, ASST Pini-CTO, Milano; ²Dipartimento di Reumatologia e Scienze Mediche - UOC Osteoporosi e Malattie Metaboliche dell Osso - ASST Pini-CTO, Milano; ³Dipartimento di Scienze Cliniche e di Comunità - Università degli Studi di Milano, Italy

  Società Italiana di Reumatologia

  https://doi.org/10.4081/reumatismo.2025.2125

  167

• PO:02:024 | Development of anti-drug antibodies in patients with peripheral and/or axial spondyloarthritis treated with infliximab or adalimumab: a monocentric cross-sectional study Gabriele Amati¹, Gilda Sandri^1|2, Alessandra Melegari³, Benedetta Bongiovanni^1|2, Giovanni Ciancio², Martina Orlandi^1|2, Ottavio Secchi¹, Dilia Giuggioli^1|2 | ¹Struttura complessa di Reumatologia, Azienda Ospedaliero-Universitaria Policlinico di Modena; ²Cattedra di Reumatologia, Università degli studi di Modena e Reggio Emilia; ³Dipartimento di medicina di laboratorio, Ospedale di Baggiovara, AUSL di Modena, Italy

  Società Italiana di Reumatologia

  https://doi.org/10.4081/reumatismo.2025.2126

  153

• PO:02:025 | Real-World Comparative Effectiveness of Upadacitinib in Psoriatic Arthritis: Evaluation of Switching to Upadacitinib Versus Tumor Necrosis Factor Inhibitors or Interleukin-17 Inhibitors After First-Line Tumor Necrosis Factor Inhibitors Valentina Carlini¹, Philip Mease², William Tillett³, Xiaolan Ye⁴, Christopher Saffore⁴, Molly Edwards⁵, Isabel Truman⁵, Sophie Barlow⁵, Jayne Stigler⁴, Bhumik Parikh⁴, Daniel Aletaha⁶ | ¹Abbvie srl Roma, Italy; ²University of Washington School of Medicine Seattle, United States Minor Outlying Islands; ³Department of Rheumatology, Royal National Hospital for Rheumatic Diseases Bath, United Kingdom; ⁴Abbvie Inc. North Chicago, United States Minor Outlying Islands; ⁵Adelphi Real World Bollington, United Kingdom; ⁶Division of Rheumatology, Department of Medicine, Medical University of Vienna, Vienna, Austria

  Società Italiana di Reumatologia

  https://doi.org/10.4081/reumatismo.2025.2286

  20

• PO:02:027 | Fast food, slow damage: ultra-processed foods, Western diet and inflammatory arthritis. A systematic scoping review Gianluca Poncina¹, Federica Gardin², Giacomo Cozzi¹, Laura Scagnellato¹, Mariagrazia Lorenzin¹, Stefano Rizzetto¹, Caterina Robusto¹, Francesca Oliviero¹, Valérie Tikhonoff², Roberta Ramonda¹. | ¹Rheumatology Unit, Department of Medicine-DIMED, University - Padova University Hospital, Padova, Italy; ²Department of Medicine-DIMED, University - Padova University Hospital, Padova, Italy.

  Società Italiana di Reumatologia

  https://doi.org/10.4081/reumatismo.2025.2010

  258

• PO:02:028 | Dal Pain Catastrophizing al Distress Psicologico Multidimensionale: esplorando la complessità dell’Artrite Psoriasica Difficult- to-Treat Francesca Saracino¹, Damiano Currado^1|2, Francesco De Vincenzo³, Francesca Trunfio¹, Annalisa Marino¹, Lyubomyra Kun¹, Erika Corberi¹, Ludovica Lamberti¹, Leonardo Frascà¹, Onorina Berardicurti^1|2, Marta Gatti¹, Marta Vomero^1|2, Roberto Giacomelli^1|2, Luca Navarini^1|2 | ¹Reumatologia e Immunologia Clinica, Dipartimento di Medicina, Università Campus Bio-Medico di Roma, Facoltà di Medicina Roma, Italy; ²Sezione Clinica e di Ricerca di Reumatologia e Immunologia Clinica, Fondazione Policlinico Campus Bio-Medico Roma, Italy; ³Dipartimento di Scienze Umane, Università Europea di Roma Roma, Italy

  Società Italiana di Reumatologia

  https://doi.org/10.4081/reumatismo.2025.2287

  14

• PO:02:030 | Retention Rate of Non-anti-TNF Therapies and primary failure in monocentric cohort of patients with Psoriatic Arthritis Alba Chiara Pozzi¹, Sofia Barezzani², Andrea Galli², Cesare Tomasi¹, Micol Frassi¹, Ilaria Cavazzana¹, Franco Franceschini¹ | ¹Rheumatology and Clinical Immunology Unit ERN-ReCONNECT, ASST Spedali Civili, University of Brescia Brescia, Italy; ²Facoltà di Medicina e Chirurgia, University of Brescia Brescia, Italy

  Società Italiana di Reumatologia

  https://doi.org/10.4081/reumatismo.2025.2288

  17

• PO:03:033 | Low Uveitis Rates in Patients with Axial Spondyloarthritis or Psoriatic Arthritis Treated with Bimekizumab: Long-Term Results from Phase 2b/3 Trials Irene E Van Der Horst-Bruinsma¹, Matthew A Brown², Floris A Van Gaalen³, Nigil Haroon⁴, Lianne S Gensler⁵, Alexander Marten⁶, Myriam Manente⁷, George Stojan⁸, Thomas Vaux⁹, Katy White⁹, Atul Deodhar¹⁰, Nicola Boffini¹¹, Martin Rudwaleit¹² | ¹Department of Rheumatology, Radboud University Medical Centre Nijmegen, The Netherlands; ²Genomics England London, United Kingdom; ³Department of Rheumatology, Leiden University Medical Center Leiden, The Netherlands; ⁴Department of Medicine/Rheumatology, University Health Network, Schroeder Arthritis Institute, University of Toronto Toronto, Canada; ⁵Department of Medicine/Rheumatology, University of California San Francisco, USA; ⁶UCB Monheim am Rhein Germany; ⁷UCB Braine-lAlleud, Belgium; ⁸UCB Atlanta, USA; ⁹UCB Slough, United Kingdom; ¹⁰Division of Arthritis and Rheumatic Diseases, Oregon Health and Science University Portland, USA; ¹¹IRCCS Ospedale San Raffaele Milan, Italy; ¹²Klinikum Bielefeld, University of Bielefeld, Bielefeld, Germany

  Società Italiana di Reumatologia

  https://doi.org/10.4081/reumatismo.2025.2289

  19

• PO:03:034 | Inhibition of Radiographic Progression with Bimekizumab Treatment Observed in bDMARD-Naïve Patients with Active Psoriatic Arthritis at 2 Years: Results from a Phase 3 Study and its Open-Label Extension Laura C Coates¹, M Elaine Husni², Mitsumasa Kishimoto³, Proton Rahman⁴, Philipp Sewerin⁵, Enrique R Soriano⁶, Barbara Ink⁷, Rajan Bajracharya⁷, Jason Coarse⁸, Philip J Mease⁹, Emanuela Mazzola¹⁰, Peter Nash¹¹ | ¹NDORMS, University of Oxford and Oxford Biomedical Research Centre, Oxford University Hospitals NHS Trust Oxford, United Kingdom; ²Department of Rheumatic and Immunologic Diseases, Cleveland Clinic Cleveland, USA; ³Department of Nephrology and Rheumatology, Kyorin University School of Medicine Tokyo, Japan; ⁴Division of Rheumatology, Craig L. Dobbin Genetics Research Centre, Memorial University of Newfoundland St. Johns, Canada; ⁵Rheumazentrum Ruhrgebiet, University Hospital of the Ruhr University Bochum Herne Germany; ⁶Hospital Italiano de Buenos Aires and University Institute Hospital Italiano de Buenos Aires Buenos Aires, Argentina; ⁷UCB Slough, United Kingdom; ⁸UCB Morrisville, USA; ⁹Department of Rheumatology, Providence-Swedish Medical Center and University of Washington Seattle, USA; ¹⁰UCB Milan, Italy; ¹¹School of Medicine, Griffith University, Brisbane, Australia

  Società Italiana di Reumatologia

  https://doi.org/10.4081/reumatismo.2025.2290

  45

• PO:03:035 | Biomarkers of Gut Epithelial Damage, Microbial Translocation, and Innate Immune Activation Characterize Patients with Axial Psoriatic Arthritis from Psoriasis Patients: Soluble Biomarker Analysis Insights from the ATTRACT Study Giulia Marchionni¹, Valentino Paci¹, Silvia Svegliati¹, Raffaella Sordillo¹, Federico Fiorini¹, Melania Giannoni¹, Anna Campanati¹, Raissa Di Zio¹, Devis Benfaremo¹, Giuseppe Lopalco², Florenzo Iannone², Ennio Lubrano³, Alberto Cauli⁴, Gianluca Moroncini¹, Dennis Poddubnyy⁵, Fabian Proft⁶, Michele M Luchetti Gentiloni¹ | ¹Marche Polytechnic University and Azienda Ospedaliero-Universitaria delle Marche, Ancona, Italy; ²University of Bari, Bari, Italy; ³Molise University, Campobasso, Italy; ⁴University of Cagliari, Azienda Ospedaliero Universitaria di Cagliari, Monserrato, Italy; ⁵University of Toronto, Toronto, Canada; ⁶Charité-Universitätsmedizin, Berlino, Germany

  Società Italiana di Reumatologia

  https://doi.org/10.4081/reumatismo.2025.2291

  14

• PO:03:036 | Psoriatic arthritis: does pre-existing treatment with cs/bDMARDs for psoriasis influence the characteristics and outcomes of joint disease? Ilenia Marchesini¹, Alberto Floris¹, Cristina Mugheddu², Laura Li Volsi¹, Maria Teresa Paladino¹, Roberta Origa¹, Jessica Sorgia¹, Mattia Congia¹, Elisabetta Chessa¹, Matteo Piga¹, Caterina Ferreli², Laura Atzori², Alberto Cauli¹ | ¹Unità di Reumatologia, AOU e Università di Cagliari-Monserrato; ²Unità di Dermatologia, AOU e Università di Cagliari, Italy

  Società Italiana di Reumatologia

  https://doi.org/10.4081/reumatismo.2025.2127

  171

• PO:03:037 | The Impact of Peripheral Joint Involvement, Pain, and Inflammatory Bowel Diseases on Drug Persistence in Axial Psoriatic Arthritis Giuseppe Lopalco¹, Sergio Del Vescovo¹, Maria Sole Chimenti², Giuliana Guggino³, Serena Guiducci⁴, Eleonora Celletti⁵, Alberto Cauli⁶, Luca Cantarini⁷, Valentino Paci⁸, Eneida Cela², Lidia La Barbera³, Gemma Lepri⁴, Myriam Di Penta⁵, Alberto Floris⁶, Alice Agostinelli⁸, Vincenzo Venerito¹, Michele Maria Luchetti⁸, Florenzo Iannone¹ | ¹Rheumatology Unit, Department of Precision and Regenerative Medicine and Ionian Area, Bari, Italy; ²Reumatology, Allergology and Clinical Immunology University of Rome Tor Vergata, Roma, Italy; ³Department of Health Promotion Sciences, Maternal and Infant Care, Internal Medicine and Medical Specialties, Palermo, Italy; ⁴Divisions of Internal Medicine and Rheumatology AOUC, Department of Experimental and Clinical Medicine, Firenze, Italy; ⁵Rheumatology Unit, SS. Annunziata Hospital of Chieti, G. D'Annunzio, Chieti, Italy; ⁶Department of Medical Science and Public Health, Cagliari, Italy; ⁷Policlinico Le Scotte, Siena, Italy; ⁸Clinical Medicine, Dipartimento di Scienze Cliniche e Molecolari, Università Politecnica delle Marche, Ancona, Italy

  Società Italiana di Reumatologia

  https://doi.org/10.4081/reumatismo.2025.2292

  13

• PO:03:039 | Extraintestinal manifestations of enteropathic arthritis vary in relation to inflammatory bowel disease behaviour, localization, and extent Bernardo D'Onofrio¹, Nicoletta Luciano^2|3, Simone Parisi¹, Maria Chiara Ditto¹, Cristina Bezzio^2|4, Enrico Fusaro¹, Alessandro Armuzzi^2|4, Carlo Selmi^2|3 | ¹Division of Rheumatology, AOU Città della Salute e della Scienza, Torino, Italy; ²Department of Biomedical Sciences, Humanitas University, Pieve Emanuele, Italy; ³Rheumatology and Clinical Immunology, IRCCS Humanitas Research Hospital, Rozzano, Italy; ⁴Inflammatory Bowel Disease Unit, IRCCS Humanitas Research Hospital, Rozzano, Italy

  Società Italiana di Reumatologia

  https://doi.org/10.4081/reumatismo.2025.2293

  15

• PO:03:044 | Impact of Inflammatory Bowel Disease on Clinical Phenotype and Treatment Response in Patients with Psoriatic Arthritis Maria Morrone¹, Maria Giannotta¹, Vincenzo Venerito¹, Greta Giulia Dipietrangelo¹, Stefano Stano¹, Florenzo Iannone¹, Giuseppe Lopalco¹ | ¹Department of Precision and Regenerative Medicine and Ionian Area DiMePRe-J University of Bari, Bari, Italy

  Società Italiana di Reumatologia

  https://doi.org/10.4081/reumatismo.2025.2294

  28

• PO:04:046 | Achieving Early Clinical Response was Associated with Cumulative Benefits on Disease Impact up to 2 Years in Patients with Active Psoriatic Arthritis Treated with Bimekizumab William Tillett^1|2, Joseph F Merola³, Iain B Mcinnes⁴, Kenneth B Gordon⁵, Richard B Warren⁶, Patrick Healy⁷, Jérémy Lambert⁸, Heather Edens⁹, Barbara Ink¹⁰, Paola Volpe¹¹, Laure Gossec¹² | ¹Royal National Hospital of Rheumatic Diseases Bath, United Kingdom; ²Department of Life Sciences, Centre for Therapeutic Innovation, University of Bath Bath, United Kingdom; ³Department of Dermatology and Department of Medicine, Division of Rheumatology, Utah Southwestern Medical Center Dallas, USA; ⁴College of Medical Veterinary and Life Sciences, University of Glasgow Glasgow, United Kingdom; ⁵Department of Dermatology, Medical College of Wisconsin Milwaukee, USA; ⁶Northern Care Alliance, NHS Foundation Trust and Manchester Academic Health Science Centre, University of Manchester Manchester, United Kingdom; ⁷UCB Morrisville, USA; ⁸UCB Colombes, France; ⁹UCB Smyrna, USA; ¹⁰UCB Slough, United Kingdom; ¹¹UOC Reumatologia, P.O. Spirito Santo Pescara, Italy; ¹²Sorbonne Universite and Pitie-Salpetriere Hospital Paris, France

  Società Italiana di Reumatologia

  https://doi.org/10.4081/reumatismo.2025.2295

  29

• PO:04:048 | Assessment of chronic and residual pain in axial spondyloarthritis in a single-center cohort of patients treated with anti-tnf agents Valentina Fornero^1|2, Niccolò Melis¹, Emanuela Salustro¹, Mattia Congia¹, Elisabetta Chessa¹, Alberto Floris¹, Matteo Piga¹, Alberto Cauli¹ | ¹Rheumatology unit, AOU e Università di Cagliari; ²Asl Biella, Ospedale degli Infermi, Ponderano (BI), Italy

  Società Italiana di Reumatologia

  https://doi.org/10.4081/reumatismo.2025.2128

  129

• PO:04:050 | Cluster-Based Endotyping of Psoriatic Arthritis in a Monocentric Italian Cohort: A Real-World study Eneida Cela¹, Arianna D'Antonio¹, Luigi Fiannacca¹, Alberto Bergamini¹, Maxime Breban², Felicie Costantino², Maria Sole Chimenti¹ | ¹Rheumatology, Allergology and Clinical Immunology, Department of System Medicine, University of Rome Tor Vergata Rome, Italy; ²Rheumatology Department, AP-HP, Ambroise-Paré Hospital Paris, France

  Società Italiana di Reumatologia

  https://doi.org/10.4081/reumatismo.2025.2296

  10

• PO:04:051 | Application of REMS in the assessment of fragility score and bone mineral density in axial spondyloarthritis and psoriatic arthritis with axial involvement Silvia Valentini¹, Stefano Gentileschi¹, Pamela Bernardini², Jurgen Sota¹, Caterina Baldi¹, Sara Torracchi², Daniela Melchiorre², Sabrina Aliberti², Emilio D'Ignazio¹, Carla Caffarelli³, Luca Cantarini¹, Serena Guiducci², Bruno Frediani¹ | ¹UOC Reumatologia, Dipartimento di Scienze mediche, chirurgiche e neuroscienze, Università degli Studi di Siena; ²SOD Reumatologia, Dipartimento di Medicina Sperimentale e clinica, Università degli studi di Firenze, AOU Careggi; ³UOC Medicina Interna e della Complessità, Dipartimento di Scienze Mediche, chirurgiche e neuroscienze, Università degli Studi di Siena, Italy

  Società Italiana di Reumatologia

  https://doi.org/10.4081/reumatismo.2025.2129

  133

• PO:04:054 | Clinical efficacy and drug retention rate of upadacitinib in patients with axial spondyloarthritis: results from a single-center observational study Simona Buonanno¹, Carla Gaggiano¹, Caterina Baldi¹, Marco Bardelli¹, Cristiana Barreca¹, Francesca Bellisai¹, Marta Fabbroni¹, Paolo Falsetti¹, Anna Paola Pata¹, Enrico Selvi¹, Jurgen Sota¹, Antonio Vitale¹, Luca Cantarini¹, Bruno Frediani¹, Stefano Gentileschi¹ | U.O.C. Reumatologia, Dipartimento di Scienze Mediche, Chirurgiche e Neuroscienze, Università di Siena, A.O.U. Senese, Italy

  Società Italiana di Reumatologia

  https://doi.org/10.4081/reumatismo.2025.2130

  154

• PO:04:056 | Willingness of patients with psoriatic arthritis to participate in pharmacological and nutritional clinical trials: a cross-sectional study Miriam Perino^1|2, Francesca Ingegnoli^1|2, Luca Ingrao^1|2, Debora Piredu^1|2, Antonio Varvaro^1|2, Camilla Riboldi^1|2, Gilberto Cincinelli², Francesca Desiati², Martina Biggioggero², Orazio De Lucia², Silvia Casari², Maria Manara², Ennio Giulio Favalli^1|2, Roberto Caporali^1|2 | ¹Università degli Studi di Milano, Dipartimento di Scienze Cliniche e di Comunità, Milano; ²ASST G. Pini-CTO, UOC di Clinica Reumatologica, Milano, Italy

  Società Italiana di Reumatologia

  https://doi.org/10.4081/reumatismo.2025.2131

  136

• PO:04:061 | Higher prevalence of baseline comorbidities in patients developing difficult to treat psoriatic arthritis Mario Ferraioli¹, Michelina Turri¹, Eneida Çela¹, Mauro Fatica¹, Paola Conigliaro¹, Elisabetta Greco¹, Alberto Bergamini¹, Maria Sole Chimenti¹. | ¹Rheumatology, Allergology and Clinical Immunology, Department of Systems Medicine, University of Rome, Tor Vergata, Rome, Italy.

  Società Italiana di Reumatologia

  https://doi.org/10.4081/reumatismo.2025.2011

  134

• PO:05:066 | Atypical diagnosis and manifestation of spondyloarthritis: a case report Adele Del Giudice¹, Filippo Crescentini², Giorgia Citriniti², Luca Cimino^1|3, Carlo Salvarani^1|2 | ¹Department of Rheumatology, Università Cattolica del Sacro Cuore, Fondazione Policlinico Universitario A. Gemelli IRCCS, Roma, Italy; ²Department of Medicine, University of Melbourne at St Vincent's Hospital Melbourne, Australia; ³Department of Rheumatology, Division of Medicine, University College, London, UK

  Società Italiana di Reumatologia

  https://doi.org/10.4081/reumatismo.2025.2132

  116

• PO:05:069 | Risankizumab efficacy in peripheral and axial involvement: monocentric experience Roberta Foti¹, Ylenia Dal Bosco¹, Giorgio Amato¹, Elisa Visalli¹, Francesco De Lucia¹, Gabriella Paolí¹, Rosario Foti¹. | ¹UOSD Reumatologia AOU Policlinico G. Rodolico-S. Marco, Catania, Italy.

  Società Italiana di Reumatologia

  https://doi.org/10.4081/reumatismo.2025.2012

  150

• PO:05:071 | Impact of age at onset on Spondyloarthritis clinical profile and quality of life: a monocentric cohort analysis Federico Fattorini¹, Marco Di Battista¹, Lorenzo Esti¹, Cosimo Cigolini², Andrea Delle Sedie², Marta Mosca^1|2, Linda Carli¹ | ¹Rheumatology Unit, Department of Clinical and Experimental Medicine, University of Pisa, Pisa, Italy; ²Rheumatology Unit, AOUP, Pisa, Italy

  Società Italiana di Reumatologia

  https://doi.org/10.4081/reumatismo.2025.2297

  29

• PO:05:074 | A clinical case of a patient affected by long-standing psoriatic arthritis and multiple comorbidities treated with an anti-IL-23 therapy Maria Letizia Currò¹, Angelo Tropea¹, Alessandra Burgio¹, Francesca Cracò¹, Antonio Pezzano¹, Federica Rapisarda¹, Antonino Palumbo¹, Valeria D'Amico¹, Fabiola Atzeni¹ | ¹Clinica Reumatologica di Udine, Dipartimento di Medicina, ASUFC, Udine, Italy

  Società Italiana di Reumatologia

  https://doi.org/10.4081/reumatismo.2025.2133

  133

• PO:06:078 | Is difficult-to-treat rheumatoid arthritis less severe in patients with autoantibody-negative disease? retrospective analysis from a monocentric cohort. Bernardo D'Onofrio¹, Maria Chiara Ditto¹, Francesco Ghellere¹, Giacomo Tanti¹, Salvatore Panaro¹, Enrico Fusaro¹, Simone Parisi¹. | ¹AOU Città della Salute e della Scienza, Torino, Italy.

  Società Italiana di Reumatologia

  https://doi.org/10.4081/reumatismo.2025.2013

  123

• PO:06:079 | Weighing the burden: how body mass index shapes clinical outcomes in rheumatoid arthritis. Insights from a large Italian cohort Marco Capodiferro¹, Marco Fornaro¹, Gian Luca Erre², Matteo Piga³, Elena Bartoloni Bocci⁴, Andreina Manfredi⁵, Ennio Giulio Favalli⁶, Maria Sole Chimenti⁷, Serena Guiducci⁸, Eleonora Celletti⁹, Addolorata Corrado¹⁰, Alessandro Giollo¹¹, Simone Parisi¹², Ivan Giovannini¹³, Elisa Gremese¹⁴, Garifallia Sakellariou¹⁵, Ombretta Viapiana¹⁶, Fabiola Atzeni¹⁷, Francesca Romana Spinelli¹⁸, Fabio Cacciapaglia^1|19. | ¹Rheumatology Unit, Department of Precision and Regenerative Medicine and Ionian Area DiMePRe-J University of Bari, Bari, Italy; ²Dipartimento di Scienze Mediche, Chirurgiche e Sperimentali, Università degli Studi di Sassari, Sassari, Italy; ³Rheumatology Unit, AOU Cagliari, Department of Medical Sciences and Public Health, University of Cagliari, Cagliari, Italy; ⁴Rheumatology Unit, Department of Medicine and Surgery, University of Perugia, Perugia, Italy; ⁵Rheumatology Unit, Azienda Ospedaliera Universitaria Policlinico of Modena, Modena, Italy; ⁶Dpt of Rheumatology, G. Pini Institute, Milano, Italy; ⁷Rheumatology, Allergology and Clinical Immunology, Department of Systems Medicine, University of Rome Tor Vergata, Rome, Italy; ⁸Department of Experimental and Clinical Medicine, Division of Rheumatology, University of Florence, Firenze, Italy; ⁹Rheumatology Unit, SS Annunziata Hospital, Chieti, Italy; ¹⁰Rheumatology Unit, Department of Medical and Surgical Sciences, University of Foggia, Foggia, Italy; ¹¹Rheumatology Unit, Department of Medicine, University of Padova Hospital Trust, Padova, Italy; ¹²Rheumatology Department, A.O.U. Città della Salute e della Scienza, Torino, Italy; ¹³Rheumatology Department, Santa Maria della Misericordia Hospital, Udine, Italy; ¹⁴Rheumatology and Clinical Immunology, IRCCS Humanitas Research Hospital, Rozzano (MI), Italy; ¹⁵Department of Internal Medicine and Therapeutics, University of Pavia, Istituti Clinici Scientifici Maugeri, Pavia, Italy; ¹⁶Rheumatology Unit, Department of Medicine, University and Azienda Ospedaliera Universitaria Integrata of Verona, Verona, Italy; ¹⁷Rheumatology Unit, Department of Experimental and Internal Medicine, University of Messina, Messina, Italy; ¹⁸Reumatology Unit, Department of Internal, Anesthesiological, and Cardiovascular Clinical Sciences, Sapienza University, Roma, Italy; ¹⁹Miulli General Hospital Acquaviva - Department of Medicine and Surgery, LUM F. De Gennaro University, Casamassima (BA), Acquaviva delle Fonti (BA), Italy.

  Società Italiana di Reumatologia

  https://doi.org/10.4081/reumatismo.2025.2014

  162

• PO:06:081 | Safety of JAK inhibitors compared to non-TNF-targeted biologic therapies in rheumatoid arthritis patients who are inadequate responders to TNF inhibitors Lorenzo Di Luozzo¹, Alessandro Giollo¹, Mariangela Salvato¹, Francesca Frizzera¹, Kiren Khalid¹, Margherita Zen¹, Andrea Doria¹ | ¹Azienda ospedaliera universitaria di Padova, unità di Reumatologia, Padova, Italy

  Società Italiana di Reumatologia

  https://doi.org/10.4081/reumatismo.2025.2298

  39

• PO:06:082 | Correlation between ultrasonographic parameters and the Krenn synovitis score in patients with chronic infiammatory arthropathy undergoing ultrasound-guided synovial biopsy: a prospective cohort study Maria Capita¹, Carlo Garaffoni¹, Marianna Tamussin¹, Serena Ceccato¹, Giovanni Lanza², Alessandra Bortoluzzi¹, Marcello Govoni¹, Ettore Silvagni¹ | ¹Unità di Reumatologia, Azienda Ospedaliero - Universitaria S. Anna, Cona (FE); ²Anatomia Patologica, Dipartimento di Medicina Traslazionale Università di Ferrara, Cona (FE), Italy

  Società Italiana di Reumatologia

  https://doi.org/10.4081/reumatismo.2025.2134

  133

• PO:06:083 | Clinical characteristics and outcomes of late- and young-onset rheumatoid arthritis in relation to autoantibody status Federica Sabatelli^1|2, Ludovico De Stefano^1|2, Clelia Zampaglione^1|2, Lisa Bergianti^1|2, Blerina Xoxi^1|2, Antonio Manzo^1|2, Carlomaurizio Montecucco^1|2, Serena Bugatti^1|2. | ¹Department of Internal Medicine and Therapeutics, University of Pavia, Pavia; ²Division of Rheumatology, IRCCS Policlinico San Matteo Foundation, Pavia, Italy.

  Società Italiana di Reumatologia

  https://doi.org/10.4081/reumatismo.2025.2015

  125

• PO:06:084 | Interstitial lung involvement in rheumatoid arthritis patients treated with abatacept: a prospective observational study Francesca Cozzini^1|2, Andreina Manfredi^2|3, Antonio Carletto⁴, Elisa Bellis⁵, Laura Cometi⁶, Vincenzo Venerito⁷, Caterina Vacchi⁸, Fabiola Atzeni⁹, Antonio Carriero¹⁰, Rosaria Foti¹¹, Mariagrazia Catanoso³, Ennio Favalli¹², Chiara Bazzani¹³, Arianna Belvedere³, Cecilia Burattini¹, Andrea Morciano⁴, Annamaria Iagnocco⁵, Gemma Lepri⁶, Florenzo Iannone⁷, Antonio Pezzano⁹, Salvatore D'Angelo¹⁰, Valentina Cateni⁴, Serena Guiducci⁶, Marco Sebastiani^1|14. | ¹Ospedale Guglielmo da Saliceto, Piacenza, Italy; ²Università degli studi di Modena e Reggio Emilia, Modena, Italy; ³IRCCS Arcispedale Santa Maria Nuova, Reggio Emilia, Italy; ⁴AOUI, Università degli studi di Verona, Verona, Italy; ⁵A.O. Mauriziano di Torino, Università degli studi di Torino, Torino, Italy; ⁶AOU di Careggi, Università degli studi di Firenze, Firenze, Italy; ⁷AOU Policlinico di Bari, università degli studi di Bari Aldo Moro, Bari, Italy; ⁸AOU Policlinico di Modena, Modena, Italy; ⁹AOU Gaetano Martino, Università degli studi di Messina, Messina, Italy; ¹⁰Azienda Ospedaliera Regionale San Carlo, Potenza, Italy; ¹¹AO Vittorio Emanuele, Catania, Italy; ¹²ASST Gaetano Pini, Milano, Italy; ¹³ASST Spedali Civili, Brescia, Italy; ¹⁴Università degli studi di Parma, Parma, Italy.

  Società Italiana di Reumatologia

  https://doi.org/10.4081/reumatismo.2025.2016

  140

• PO:06:086 | Updated Systematic Literature Review and meta-analysis to Inform the Italian Society of Rheumatology Recommendations on the Treatment of Rheumatoid Arthritis-Associated Interstitial Lung Disease Angelo Fassio¹, Marco Sebastiani^9|10, Francesco Pollastri¹, Chiara Crotti⁴, Nicola Ughi⁵, Enrico De Lorenzis⁶, Silvia Mancuso⁷, Massimo Radin⁸, Francesca Cozzini⁹, Greta Carrara¹¹, Gianpiero Landolfi¹¹, Roberto Rozza¹¹, Andreina Manfredi^2|3 | ¹Rheumatology Unit, University of Verona, Verona, Italy; ²University of Modena and Reggio Emilia, Reggio Emilia, Italy; ³Rheumatology Unit, AUSL-IRCCS, Reggio Emilia, Italy; ⁴Bone Disease Unit, Department of Rheumatology and Medical Science, ASST-G.Pini-CTO, Milan, Italy; ⁵Division of Rheumatology, Multispecialist Medical Department, ASST Grande Ospedale Metropolitano Niguarda, Milano, Italy; ⁶Department of Aging Diseases, Orthopedic and Rheumatology, Rheumatology Division, P. Gemelli, Roma, Italy; ⁷Rheumatology Unit, Department of Clinical, Internal, Anaesthesiologic and Cardiovascular, Sciences, Sapienza, Roma, Italy; ⁸CMID, San Giovanni Bosco Hub Hospital ASL Città di Torino and Department of Clinical and Biological Sciences, Turin, Italy; ⁹Department of Medicine and Surgery, University of Parma, Parma, Italy; ¹⁰Rheumatology Unit, AUSL Piacenza, Piacenza, Italy; ¹¹Unità Epidemiologica, SIR, Società Italiana di Reumatologia, Milano, Italy

  Società Italiana di Reumatologia

  https://doi.org/10.4081/reumatismo.2025.2299

  20

• PO:06:088 | Are all Difficult-To-Treat RA patients the same? Insights into clinical features and drug discontinuation Silvia Di Noto¹, Cristina Garufi¹, Letizia Caruso¹, Fulvia Ceccarelli¹, Cristiano Alessandri¹, Federica Ucci¹, Valerio Fiorilli¹, Fabrizio Conti¹, Francesca Romana Spinelli¹ | ¹Sapienza University of Rome, Dipartimento di Scienze Cliniche Internistiche, Anestesiologiche e Cardiovascolari, Roma, Italy

  Società Italiana di Reumatologia

  https://doi.org/10.4081/reumatismo.2025.2300

  40

• PO:06:089 | Heat-not-burn cigarettes induce protein post-translational modifications (PTM): possible role in the pathogenesis of rheumatoid arthritis Claudia Ciancarella¹, Federica Maria Ucci¹, Valeria Manganelli², Elena Fasciolo², Roberta Priori¹, Fulvia Ceccarelli¹, Manuel Sergi³, Camilla Montesano³, Francesco Bartolini³, Maurizio Sorice², Cristiano Alessandri¹, Fabrizio Conti¹ | ¹Rheumatology Unit, Department of Internal Medicine, Anesthesiology and Cardiovascular Sciences, La Sapienza, Roma, Italy; ²Department of Experimental Medicine, La Sapienza University of Rome, Italy; ³Department of Chemistry, La Sapienza University Of Rome, Italy

  Società Italiana di Reumatologia

  https://doi.org/10.4081/reumatismo.2025.2301

  19

• PO:06:090 | Validation of 'Clinical Red Flags' for RA-ILD in an Italian cohort: the role fo Dyspnea, Cough and Crackles Eneida Cela¹, Chiara Bonini¹, Francesco Cavalli², Alessandra Luciano³, Barbara Kroegler¹, Josuel Ora², Alberto Bergamini¹, Marcello Chiocchi³, Paola Rogliani², Paola Conigliaro¹, Maria Sole Chimenti¹ | ¹Rheumatology, Allergology and Clinical Immunology, Department of System Medicine, University of Rome Tor Vergata, Rome, Italy; ²Division of Respiratory Medicine, University Hospital Policlinico Tor Vergata, Rome, Italy; ³Department of Diagnostic Imaging and Interventional Radiology, University of Rome, Tor Vergata, Rome, Italy

  Società Italiana di Reumatologia

  https://doi.org/10.4081/reumatismo.2025.2302

  16

• PO:06:092 | Early achievement of remission confers better outcomes than low disease activity in both seropositive and seronegative patients with new-onset rheumatoid arthritis Clelia Zampaglione^1|2, Ludovico De Stefano^1|2, Federica Sabatelli^1|2, Alessio D'Isanto^1|2, Blerina Xoxi^1|2, Antonio Manzo^1|2, Carlomaurizio Montecucco^1|2, Serena Bugatti^1|2. | ¹Department of Internal Medicine and Therapeutics, University of Pavia, Pavia; ²Division of Rheumatology, IRCCS Policlinico San Matteo Foundation, Pavia, Italy.

  Società Italiana di Reumatologia

  https://doi.org/10.4081/reumatismo.2025.2017

  148

• PO:06:093 | Clinical and ultrasound phenotyping comparison between Difficult-To-Treat Rheumatoid Arthritis (D2TRA) and non-D2TRA patients: experience from a monocentric cohort Silvia Perrone¹, Claudio Cruciani¹, Silvia Mascolo¹, Elisa Bellis¹, Gloria Crepaldi¹, Valeria Data¹, Claudia Garulli¹, Claudia Lomater¹, Elena Marucco¹, Marta Saracco¹, Mariele Gatto¹, Annamaria Iagnocco¹. | ¹Academic Rheumatology Centre, Department of Clinical and Biological Sciences, University of Turin, AO Mauriziano, Turin, Italy.

  Società Italiana di Reumatologia

  https://doi.org/10.4081/reumatismo.2025.2018

  127

• PO:06:094 | Exploring the relationship between inflammation and collagen deposition in synovial tissue and clinical outcomes in active arthritis: insights from a monocentric pilot study Dario Bruno¹, Barbara Tolusso¹, Daniela Renna¹, Mohamed Hegazi², Fabio Pasqualini², Marta Caprioli¹, Giacomo Maria Guidelli¹, Tommaso Hubert³, Nicoletta Luciano^1|3, Marzia Monferini³, Natasa Isailovic³, Fabio Grizzi^2|3, Salvatorelorenzo Renne³, Costantino Pitzalis^1|3|4, Elisa Gremese^1|3. | ¹Rheumatology and Clinical Immunology, IRCCS Humanitas Research Hospital, Rozzano (MI); ²Department of Immunology and Inflammation, IRCCS Humanitas Research Hospital, Milano; ³Department of Biomedical Sciences, Humanitas University, Rozzano (MI), Italy; ⁴Centre for Experimental Medicine and Rheumatology, Queen Mary University of London, London, UK

  Società Italiana di Reumatologia

  https://doi.org/10.4081/reumatismo.2025.2019

  126

• PO:07:095 | Clinical impact of therapeutic modification following changes in AIFA reimbursement criteria for JAK inhibitors in patients with RA in remission/low disease activity: analysis of the multicenter JAK-SWAP RER study in Emilia-Romagna Marta Raschella¹, Giulia Furia¹, Martina Di Nunzio¹, Francesco Luca Renzullo², Francesco Girelli², Federica Pignatti³, Francesco Ursini³, Licia Vultaggio⁴, Pierluigi Cataleta⁴, Elena Bravi⁵, Eugenio Arrigoni⁵, Francesca Bergossi⁶, Enrica Vandelli⁷, Massimo Reta^6|7, Viola Magnani⁸, Andreina Manfredi^8|9, Giuseppe Germanò⁸, Alessandra Bortoluzzi¹, Marcello Govoni¹, Ettore Silvagni¹ | ¹Unità Operativa Complessa di Reumatologia, Dipartimento di Scienze Mediche, Università degli Studi di Ferrara e Azienda Ferrara; ²UOS Reumatologia, Ospedale GB Morgagni, Forlì; ³UOC Reumatologia, Istituto ortopedico Rizzoli, Bologna; ⁴UO Reumatologia, AUSL Romagna Ospedale di Ravenna; ⁵UO Reumatologia, Azienda USL di Piacenza; ⁶Reumatologia Osp. Maggiore, Bologna; ⁷UO Medicina Interna ad Indirizzo Reumatologico Interaziendale ^SC AUSL Bologna, IRCCS Policlinico di SantOrsola, Bologna; ⁸U.O Reumatologia, Santa Maria Nuova di Reggio Emilia; ⁹Università degli studi di Modena e Reggio Emilia, Italy

  Società Italiana di Reumatologia

  https://doi.org/10.4081/reumatismo.2025.2135

  156

• PO:07:096 | Safety of filgotinib in the treatment of rheumatoid arthritis: results from the multicentre SOFIA study Anna Giorgia Osele¹, Matteo Filippini², Eugenio Capparelli³, Eleonora Bruschi⁴, Bernd Raffeiner⁵, Silvano Bettio⁶, Mariangela Salvato¹, Federico Arru⁷, Massimiliano Limonta⁴, Paola Faggioli³, Elda Piovani², Eleonora Zaccara³, Alessandro Giollo¹, Margherita Zen¹ | ¹UOC Reumatologia, Azienda Ospedale-Università di Padova; ²UO Reumatologia e Immunologia Clinica, ASST Spedali Civili, Brescia; ³UOC Ruematologia, ASST Ovest Milanese, Legnano ^MI; ⁴SSD Reumatologia, ASST Papa Giovanni XXIII, Bergamo; ⁵Dipartimento di Reumatologia, Ospedale di Formazione Paracelsus ^ASDAA-SABES, Bolzano; ⁶Medicina Generale Unità 1^, Centro Regionale per le Malattie Rare Immunologiche e Reumatologiche, Ospedale Universitario Treviso; ⁷UO Medicina, ASL 3 Nuoro, Italy

  Società Italiana di Reumatologia

  https://doi.org/10.4081/reumatismo.2025.2136

  141

• PO:07:097 | CGRP and CALCRL localization supports the role of fibroblast-like synoviocytes in rheumatoid arthritis pain pathways Giada La Spina¹, Cristina Garufi², Mattia Caliste², Martina Leopizzi³, Valeria Di Maio³, Cristiano Alessandri², Fabrizio Conti², Francesca Romana Spinelli² | ¹Sapienza University of Rome, Dipartimento di Medicina Molecolare, Roma, Italy; ²Sapienza University of Rome, Dipartimento di Scienze Cliniche Internistiche, Anestesiologiche e Cardiovascolari, Roma, Italy; ³Sapienza University of Rome, Dipartimento di Scienze e Biotecnologie Medico-Chirurgiche, Roma, Italy

  Società Italiana di Reumatologia

  https://doi.org/10.4081/reumatismo.2025.2303

  15

• PO:07:098 | Reasons for treatment failure and their synovial correlate among patients with difficult-to-treat rheumatoid arthritis Alessandro Giollo¹, Mariangela Salvato¹, Francesca Frizzera¹, Kiren Khalid¹, Lorenzo Di Luozzo¹, Carlo Garaffoni², Maria Capita², Marianna Tamussin², Giovanni Lanza², Marny Fedrigo³, Annalisa Angelini³, Roberta Ramonda¹, Ettore Silvagni², Andrea Doria¹ | ¹UOC Reumatologia Padova, Italy; ²UOC Reumatologia Ferrara, Italy; ³UOC Patologia cardiovascolare Padova, Italy; ⁴UOC Anatomia Patologica Ferrara, Italy

  Società Italiana di Reumatologia

  https://doi.org/10.4081/reumatismo.2025.2304

  19

• PO:07:099 | Survival on therapy of certolizumab pegol in rheumatoid arthritis, psoriatic arthritis, and spondyloarthritis: 8-year data from an Italian multicenter register Maria Manara¹, Gilberto Cincinelli^1|2, Marco Fornaro³, Simone Perniola⁴, Elisa Gremese⁵, Chiara Bazzani⁶, Serena Bugatti⁷, Francesca Romana Spinelli⁸, Rosario Foti⁹, Marco Sebastiani¹⁰, Alberto Cauli¹¹, Fabiola Atzeni¹², Giovanni Lapadula¹³, Gianfranco Ferraccioli¹⁴, Fabrizio Conti⁸, Florenzo Iannone³, Roberto Caporali^1|2 | ¹Department of Rheumatology and Medical Sciences, ASST G. Pini-CTO Milano; ²Department of Clinical Sciences and Community Health, University of Milan; ³Department of Precision and Regenerative Medicine and Ionian Area, University of Bari; ⁴Clinical Immunology Division, Fondazione Policlinico Universitario A. Gemelli IRCCS, Roma; ⁵Rheumatology and Clinical Immunology, IRCCS Humanitas Research Hospital, Rozzano (MI); ⁶Unit of Rheumatology and Clinical Immunology, ASST Spedali Civili Brescia; ⁷Department of Internal Medicine and Therapeutics, Università di Pavia; ⁸Rheumatology Unit, Dipartimento Scienze Cliniche Internistiche, Anestesiologiche e Cardiovascolari, Sapienza University, Roma; ⁹Rheumatology Unit, San Marco Hospital, Policlinico University of Catania; ¹⁰Rheumatology Unit, AUSL Piacenza, University of Parma; ¹¹UOC di Reumatologia, Dipartimento di Scienze Mediche e Sanità Pubblica, Azienda Ospedaliero-Universitaria di Cagliari; ¹²Rheumatology Unit, Department of Experimental and Internal Medicine, University of Messina; ¹³Gruppo Italiano di Studio sulla Early Arthritis, GISEA, Bari; ¹⁴Department of Medicine, Università Cattolica del Sacro Cuore, Fondazione IRCCS Policlinico Gemelli, Roma, Italy

  Società Italiana di Reumatologia

  https://doi.org/10.4081/reumatismo.2025.2137

  156

• PO:07:101 | Efficacy and safety of methotrexate in a cohort of patients affected by early-onset rheumatoid arthritis: a monocentric real-life study Carlo Cauli¹, Martina Favretti², Giulio Dolcini², Vincenzo Ferraro¹, Cristina Iannuccelli³, Fabrizio Conti¹, Manuela Di Franco¹ | ¹UOC Reumatologia, Dipartimento di scienze cliniche internistiche anestesiologiche e cardiovascolari, Sapienza, Roma; ²Dipartimento di Medicina Molecolare, La Sapienza, Roma; ³UOC Reumatologia, AOU Policlinico Umberto I, La Sapienza, Roma, Italy

  Società Italiana di Reumatologia

  https://doi.org/10.4081/reumatismo.2025.2138

  155

• PO:07:102 | Predicting success with baricitinib in rheumatoid arthritis: efficacy across ages and serological profiles Daniele Lini¹, Matteo Colina², Romina Andracco³, Francesca Ometto⁴, Viviana Ravagnani⁵, Alberto Lo Gullo⁶, Simone Parisi⁷, Antonella Farina⁸, Patrizia Del Medico⁹, Marino Paroli¹⁰, Olga Addimanda¹, Alessandra Bezzi¹¹, Federica Lumetti¹², Aldo Biagio Molica Colella¹³, Davide Murgia¹⁴, Maddalena Larosa¹⁵, Aurora Ianniello¹⁶, Elena Bravi¹⁷, Marta Priora¹⁸, Palma Scolieri¹⁹, Alessandro Volpe²⁰. | ¹Azienda Unità Sanitaria Locale di Bologna -- Policlinico S.Orsola- Azienda Ospedaliera Universitaria-IRCCS di Bologna, Bologna; ²Rheumatology Service. Department of Medicine and Oncology, Ospedale Santa Maria della Scaletta, Imola; ³Imperia Hospital, Internal Medicine Unit, Rheumatology outpatient clinic, Imperia; ⁴Azienda ULSS 6 Euganea, Rheumatology Outpatient Clinic, Padova; ⁵Santa Chiara Hospital APSS Trento, Rheumatology Unit, Trento; ⁶ARNAS Garibaldi di Catania, Rheumatology Unit, Catania; ⁷Azienda Ospedaliera Universitaria Città della Salute e della Scienza di Torino, Rheumatology Department, Torino; ⁸Ospedale A. Murri di Fermo, Internal Medicine Unit, Rheumatology outpatient clinic, Fermo; ⁹Civitanova Marche Hospital, Rheumatology outpatient clinic - Internal Medicine Unit, Civitanova Marche; ¹⁰Sapienza University of Rome, Polo Pontino, Department of Clinical, Anesthesiological and Cardiovascular Sciences, Latina; ¹¹ASL Romagna Rimini, Internal Medicine and Rheumatology Unit, Rimini; ¹²Azienda USL of Modena and University Hospital Policlinico di Modena, Rheumatology Unit, Modena; ¹³Rheumatology Unit, Azienda Ospedaliera Papardo, Messina; ¹⁴ASL VC Ospedale S. Andrea, Unit of Rheumatology, Vercelli; ¹⁵Azienda Sanitaria Locale 3 Genova, Division of Rheumatology - Medical Specialties Department, Genova; ¹⁶ASL Novara, Rheumatology Outpatient Unit, Novara; ¹⁷Ospedale G. Da Saliceto, Rheumatology Unit, Piacenza; ¹⁸ASL CN1, Rheumatology Day Hospital and outpatient clinic, Mondovì (CN); ¹⁹Nuovo Regina Margherita Hospital, Department of Medical Specialties, Roma; ²⁰IRCCS Sacro Cuore Don Calabria Hospital, Unit of Rheumatology, Negrar, Italy.

  Società Italiana di Reumatologia

  https://doi.org/10.4081/reumatismo.2025.2020

  137

• PO:07:103 | Tocilizumab use in patients with rheumatoid arthritis and malignancy: a monocentric experience Vittorio Dibenedetto^1|2|3, Nicola Farina^1|2, Nicola Boffini^1|2, Alessandro Tomelleri^1|2, Adriana Cariddi^1|2, Elena Baldissera^1|2, Marco Matucci-Cerinic^1|2|3, Lorenzo Dagna^1|2|3. | ¹Unit of Immunology, Rheumatology, Allergy and Rare Diseases, IRCCS San Raffaele Hospital, Milano, Italy; ²Inflammation, Fibrosis and Ageing Intitiative ^INFLAGE, IRCCS San Raffaele Hospital, Milano, Italy; ³Vita-Salute San Raffaele University, Milano, Italy.

  Società Italiana di Reumatologia

  https://doi.org/10.4081/reumatismo.2025.2021

  135

• PO:07:107 | Performance of the 2010 ACR/EULAR classification criteria for Rheumatoid Arthritis in a group of elderly onset patients Alessandra Rai¹, Pierluigi Macchioni¹, Giovanni Barausse², Luigi Boiardi¹, Giuseppe Paolazzi², Carlo Salvarani¹, Andreina Manfredi¹ | ¹University of Modena and Reggio Emilia, USL-IRCCS Reggio Emilia, Italy; ²Rheumatology Unit, Ospedale di Trento, Italy

  Società Italiana di Reumatologia

  https://doi.org/10.4081/reumatismo.2025.2305

  30

• PO:07:108 | Achievement of Treatment Targets and Maintenance of Response with Upadacitinib in Patients with Moderate-to-Severe Rheumatoid Arthritis in a Real-world Setting: Final 2-year Outcomes from the UPHOLD Study Enrico Marchetta¹, Andrew Östör^2|8, Eugen Feist³, Prodromos Sidiropoulos⁴, Jérôme Avouac⁵, Martin Rebella^6|7, Rajaie Namas⁹, Erin Mcdearmon Blondell¹⁰, Ivan Lagunes¹⁰, Tianming Gao¹⁰, Tim Shaw¹⁰, Suzan Attar¹¹ | ¹AbbVie Srl Roma, Italy; ²Monash University and Emeritus Research, Melbourne, Victoria, Melbourne, Australia; ³Helios Department of Rheumatology and Clinical Immunology, Vogelsang-Gommern, Vogelsang Gommern, Germany; ⁴Faculty of Medicine, University of Crete, Heraklion, Heraklion, Greece; ⁵Service de Rhumatologie, Hôpital Cochin, AP HP Centre Université Paris Cité, Parigi, France; ⁶Departamento de Medicina, Facultad de Medicina, Universidad de la República, Montevideo, Montevideo, Uruguay; ⁷Unidad de Enfermedades Autoinmunes Sistémicas, MUCAM, Montevideo, Montevideo, Uruguay; ⁸Australian National University, Camberra, Australia; ⁹Medical Subspecialties Institute, Division of Rheumatology, Cleveland Clinic Abu Dhabi, United Arab Emirates; ¹⁰AbbVie Inc., North Chicago, Illinois, United States of America Chicago, USA; ¹¹King Abdulaziz University, Jeddah, Saudi Arabia

  Società Italiana di Reumatologia

  https://doi.org/10.4081/reumatismo.2025.2306

  22

• PO:07:111 | Worsening of patient-reported outcomes is an early predictor of disease flare in patients with rheumatoid arthritis in course of treatment with conventional synthetic disease modifying anti-rheumatic drugs Ludovico De Stefano^1|2, Federica Sabatelli^1|2, Clelia Zampaglione^1|2, Blerina Xoxi², Antonio Manzo^1|2, Carlomaurizio Montecucco^1|2, Serena Bugatti^1|2. | ¹Department of Internal Medicine and Therapeutics, University of Pavia, Pavia, Italy; ²Division of Rheumatology, IRCCS Policlinico San Matteo Foundation, Pavia, Italy.

  Società Italiana di Reumatologia

  https://doi.org/10.4081/reumatismo.2025.2022

  144

• PO:08:113 | Shaping rheumatoid arthritis treatment: clinical and demographic drivers of tsDMARDs versus bDMARDs prescription post-EMA pronouncement on JAK inhibitors - insights from the AMBI-RA study Riccardo Bertola¹, Beatrice Maranini¹, Carlo Garaffoni¹, Maria Pozzuto¹, Anna Laura Riva Cambrino¹, Alessandro Spinelli¹, Letizia Mamprin¹, Federico Agostini¹, Martina Di Nunzio¹, Marcello Govoni¹, Alessandra Bortoluzzi¹, Ettore Silvagni¹ | ¹Rheumatology Unit, Department of Medical Sciences, University of Ferrara and Azienda Ospedaliero-Universitaria S. Anna, Italy

  Società Italiana di Reumatologia

  https://doi.org/10.4081/reumatismo.2025.2139

  164

• PO:08:114 | The adjuvanted recombinant zoster vaccine is effective in preventing herpes zoster among patients ≥50 years of age with selected autoimmune diseases in the united states: a real-world database analysis (2018–2021) Rosaria Silvestri¹, Dagna Constenla², Germain Lonnet³, Emmanuel Aris³, Nathalie Servotte³, Ramsanjay Rk⁴, Agnes Mwakingwe-Omari², Huifeng Yun² | ¹GSK Verona, Italy; ²GSK Rockville, USA; ³GSK Wavre, Belgium; ⁴GSK Bengaluru, India

  Società Italiana di Reumatologia

  https://doi.org/10.4081/reumatismo.2025.2140

  159

• PO:08:116 | Rheumatoid nodulosis: incidence, clinical/instrumental description, and phenotypic correlations in patients with rheumatoid arthritis treated with b-DMARDs. A real-life analysis from a monocentric cohort Stefano Ruggiero¹, Elisa Montebelli³, Simone Bernardi², Marcello Natali⁴, Francesca Martelli¹, Alessandra Caula¹, Federica Landolfini¹, Gabriella Cucinotta¹, Sofia Giulianelli¹, Francesco Girelli² | ¹UOC Medicina Interna, Ospedale Morgagni-Pierantoni; Dipartimento di scienze Mediche e Chirurgiche Università di Bologna; ²UOS Reumatologia, Ospedale Morgagni-Pierantoni, Forlì; ³Università degli Studi di Bologna; ⁴UOC Radiologia, Ospedale Morgagni-Pierantoni, Forlì, Italy

  Società Italiana di Reumatologia

  https://doi.org/10.4081/reumatismo.2025.2141

  141

• PO:08:117 | Association between the use of oral contraceptives and the development of rheumatoid arthritis: a systematic review and meta-analysis Annalisa Marino¹, Damiano Currado^1|2, Onorina Berardicurti^1|2, Marta Vomero², Lyubomyra Kun¹, Letizia Pia Di Corcia², Erika Corberi², Francesca Trunfio², Francesca Saracino², Ludovica Lamberti², Leonardo Frasca², Angelo Battista³, Marta Alfano⁴, Silvia Schiavone⁵, Roberto Giacomelli^1|2, Luca Navarini^1|2. | ¹Clinical and Research Section of Rheumatology and Clinical Immunology, Fondazione Campus Bio-Medico, Roma; ²Rheumatology and Clinical Immunology, Department of Medicine, University of Rome Campus Biomedico, School of Medicine, Roma; ³Department of Maternal Science, Paediatric Emergency Service, Sapienza University of Rome, Roma; ⁴Department of Experimental Medicine, Sapienza University of Rome, Roma; ⁵Department of Orthopaedics and Traumatology, Policlinico Tor Vergata Foundation, Roma, Italy

  Società Italiana di Reumatologia

  https://doi.org/10.4081/reumatismo.2025.2023

  130

• PO:08:118 | “Posting Arthritis”: rheumatoid arthritis vs. juvenile idiopathic arthritis contents on social media Daniele Domanico¹, Saverio La Bella^2|3, Angelica Napoletano¹, Teresa Caferri¹, Angela Carenza¹, Armando Di Ludovico², Marta Rinaldi⁴, Simone Perniola¹, Vincenzo Venerito¹, Giuseppe Lopalco¹, Florenzo Iannone¹. | ¹Rheumatology Unit Department of Precision and Regenerative Medicine Jonian Area, Bari; ²Pediatric Rheumatology Unit University of Chieti-Pescara, Chieti; ³UOC Rheumatology and Autoinflammatory Diseases, IRCCS Istituto Giannina Gaslini, Genova, Italy; ⁴Paediatric Department, John Radcliffe Hospital Oxford University Hospitalsù, Oxford, UK

  Società Italiana di Reumatologia

  https://doi.org/10.4081/reumatismo.2025.2024

  153

• PO:08:119 | Infusional Advantage: Rituximab’s Role in Enhancing Adherence in Multimorbid Rheumatoid Arthritis Marco Capodiferro¹, Daniele Domanico¹, Angelica Napoletano¹, Giulia Righetti², Patrizia Suppressa², Vincenzo Venerito¹, Giuseppe Lopalco¹, Florenzo Iannone¹, Fabio Cacciapaglia^1|2 | ¹Rheumatology Unit, Department of Precision and Regenerative Medicine and Jonian Area DiMePRe-J University of Bari, Italy; ²Department of Medicine and Surgery, Miulli General Hospital Acquaviva delle Fonti - LUM University Casamassima Bari Acquaviva delle Fonti, Bari, Italy

  Società Italiana di Reumatologia

  https://doi.org/10.4081/reumatismo.2025.2307

  14

• PO:08:121 | Correlation between SENS score and perceived disability in a monocentric cohort of patients affected by rheumatoid arthritis: preliminary analysis of 209 patients Francesco Angius¹, Nicoleta Anamari Costin¹, Mattia Fadda¹, Davide Corradini², Mattia Congia², Elisabetta Chessa², Alberto Floris¹, Matteo Piga^{1 -2}, Alberto Cauli^{1 -2} | ¹SC Reumatologia, Dipartimento di Scienze Mediche e Salute Pubblica, Università di Cagliari; ²SC Reumatologia, AOU Cagliari, Italy

  Società Italiana di Reumatologia

  https://doi.org/10.4081/reumatismo.2025.2142

  118

• PO:08:124 | An exploratory analysis of risk factors for methotrexate-associated osteopathy: a retrospective study Federico Aldegheri¹, Francesca Ruzzon¹, Matteo Appoloni¹, Maurizio Rossini¹, Giovanni Adami¹, Davide Gatti¹, Ombretta Viapiana¹, Angelo Fassio¹ | ¹Università di Verona, Italy

  Società Italiana di Reumatologia

  https://doi.org/10.4081/reumatismo.2025.2308

  30

• PO:08:126 | Use of upadacitinib in real-life: the experience of Calabrian rheumatology Vincenzo Raimondo¹, Maurizio Caminiti², Pietro Gigliotti³, Giuseppe Varcasia⁴, Massimo L'Andolina⁵, Domenico Olivo⁶, Roberta Pellegrini⁷, Pietro Muto⁸, Marilena Calabria⁹, Laura Massaro¹⁰, Jessica Maria El Luppino¹¹, Salvatore De Bonis¹², Giuseppa Pagano Mariano², Stefania Sorbara³, Virginia Caira⁴, Mariateresa Cirillo⁵, Caterina Bruno⁹, Clodoveo Ferri¹¹ | ¹UOC di Reumatologia, Dipartimento SCIAC, Sapienza Università di Roma; ²Dipartimento di Medicina, Clinica di Reumatologia, Università degli Studi di Udine; ³UOC Medicina Interna e Nefrologia, Dipartimento MeSVA, Università degli Studi di L'Aquila; ⁴UniCamillus, San Camillo Università Internazionale di Scienze della Salute di Roma, Italy; ⁵Ambulatorio di Reumatologia, Ospedale di Tropea, Tropea, Italy; ⁶ASP Crotone, Ambulatorio di Reumatologia, Crotone, Italy; ⁷Ambulatorio di Reumatologia, Ospedale Annunziata di Cosenza, Cosenza, Italy; ⁸Ambulatorio di Reumatologia, Ospedale di Paola, Paola, Italy; ⁹Ambulatorio di Reumatologia, SOC di Medicina Interna, AOU Dulbecco, Catanzaro, Italy; ¹⁰Ambulatorio di Reumatologia, Ospedale di Praia a Mare, Praia a Mare, Italy; ¹¹Casa di Cura Madonna dello Scoglio, Reparto di Reumatologia, Cotronei, Italy - Affiliazione 12: Ambulatorio di Reumatologia, ospedale di Acri, Acri, Italy  

  Società Italiana di Reumatologia

  https://doi.org/10.4081/reumatismo.2025.2143

  138

• PO:09:134 | The impact of intra-articular hyaluronic acid injections on osteoarthritis synovitis: a study on synovial tissue of total knee arthroplasty patients Orazio De Lucia¹, Laura Giudice^1|2, Carolina Artusi¹, Luca Ingrao^1|2, Giorgia Trignani^1|2, Matteo Ferrito¹, Andrea Amati^1|2, Marta Arese^1|2, Camilla Riboldi^1|2, Isabella Scotti¹, Antonella Murgo¹, Ennio Giulio Favalli^1|2, Antonina Parafioriti³, Elisabetta Armiraglio³, Andrea Di Bernardo³, Filippo Calanna⁴, Chiara Fossati⁴, Pietro Simone Randelli^4|5, Roberto Felice Caporali^1|2 | ¹Dipartimento di Reumatologia e Scienze Mediche,ʁSST Centro Specialistico Ortopedico Traumatologico Gaetano Pini-CTO, Milano; ²Dipartimento di Scienze Cliniche e di Comunità, Università degli Studi di Milano; ³UOC Anatomia Patologica, ASST Centro Specialistico Ortopedico Traumatologico Gaetano Pini-CTO, Milano; ⁴UOC 1° Clinica Ortopedica, ASST Centro Specialistico Ortopedico Traumatologico Gaetano Pini-CTO, Milano; ⁵Università degli Studi di Milano, Dipartimento di Scienze Biomediche per la Salute, Milano, Italy

  Società Italiana di Reumatologia

  https://doi.org/10.4081/reumatismo.2025.2144

  140

• PO:09:139 | Comparative evaluation of GPT-4.0, Claude 4, and MedGEMMA in automatic Kellgren-Lawrence grading of knee osteoarthritis Teresa Caferri¹, Vincenzo Venerito¹, Angela Carenza¹, Daniele Catamerò¹, Daniele Domanico¹, Sergio Del Vescovo¹, Lucia Cristiana Colaprico¹, Lavista Marlea¹, Maria Giannotta¹, Giuseppe Lopalco¹, Florenzo Iannone¹. | ¹Rheumatology Unit, Department of Precision and Regenerative Medicine and Jonian Area, University of Bari, Bari, Italy.

  Società Italiana di Reumatologia

  https://doi.org/10.4081/reumatismo.2025.2025

  176

• PO:10:141 | A Case Study: Navigating the VEXAS Syndrome Mimickers Erika Montabone¹, Richard Borrelli¹, Nicolò Rashidy¹, Fabiana Giannoccaro², Giuseppe Guida², Federico Itri³, Renato Carignola⁴, Simone Negrini¹, Stefania Nicola¹, Luca Lo Sardo¹, Iuliana Badiu¹, Federica Corradi¹, Ambra Bonvicino⁵, Maurizio Balbi⁶, Luisa Brussino¹ | ¹SCDU Immunologia e Allergologia, AO Mauriziano, Dipartimento di Scienze Mediche, Università degli Studi di Torino Torino, Italy; ²SSD Asma grave, malattie rare del polmone e fisiopatologia respiratoria, AOU San Luigi Gonzaga Orbassano, Italy; ³SCDU Medicina Interna ad indirizzo Ematologico, AOU San Luigi Gonzaga Orbassano, Italy; ⁴SCDU Medicina Interna, Scleroderma Unit, AOU San Luigi Gonzaga Orbassano, Italy; ⁵SCDU Dermatologia, Città della Salute e della Scienza di Torino Torino, Italy; ⁶SCDU Radiodiagnostica, AOU San Luigi Gonzaga, Dipartimento di Oncologia Orbassano, Italy

  Società Italiana di Reumatologia

  https://doi.org/10.4081/reumatismo.2025.2309

  43

• PO:10:144 | Management of pure red cell aplasia as the onset of systemic lupus erythematosus: a case report Chrystel Carolin Navarrete Cadena¹, Marika Tardella¹ | ¹Università Politecnica delle Marche Jesi, Ancona, Italy

  Società Italiana di Reumatologia

  https://doi.org/10.4081/reumatismo.2025.2310

  40

• PO:10:146 | Dorsal myelopathy in a patient with radiographic axial spondyloarthritis Chiara Nobili¹, Siria Ripiccini¹, Marco Panetta¹, Elisabetta Greco¹, Barbara Kroegler¹, Paola Conigliaro¹, Alberto Bergamini¹, Maria Sole Chimenti¹ | ¹Università degli Studi di Roma-Tor Vergata, Italy

  Società Italiana di Reumatologia

  https://doi.org/10.4081/reumatismo.2025.2145

  125

• PO:10:149 | Efficacy of anifrolumab in a case of systemic lupus erythematosus with pulmonary involvement Fabio Brandolino¹, Giulia Pazzola¹, Luca Ronzoni³, Andreina Teresa Manfredi^1|2, Carlo Salvarani^1|2 | ¹SC Reumatologia, IRCCS Arcispedale Santa Maria Nuova, AUSL Reggio Emilia; ²Università di Modena e Reggio Emilia, Scuola di specializzazione in Reumatologia, Modena; ³SC Malattie dell'Apparato Respiratorio, IRCCS Arcispedale Santa Maria Nuova, AUSL Reggio Emilia, Italy

  Società Italiana di Reumatologia

  https://doi.org/10.4081/reumatismo.2025.2146

  185

• PO:10:150 | A case of pulmonary hypertension in Whipple's disease Alba Chiara Pozzi^1|2, Giulia Fontana^1|2, Francesca Crisafulli^1|2, Guarino Daniele³, Monica Salvi³, Massimiliano Palazzini³, Francesco Biagi^4|5, Ilaria Cavazzana^1|2, Franco Franceschini^1|2, Micol Frassi¹. | ¹Rheumatology and Clinical Immunology Unit ERN-ReCONNECT, ASST Spedali Civili, Brescia, Italy; ²Department of Clinical Experimental Sciences, University of Brescia, Brescia; ³IRCCS Azienda Ospedaliero-Universitaria di Bologna, University of Bologna, Cardiology Unit, DIMEC, Bologna; ⁴University of Pavia, Department of Internal Medicine and Therapeutics, Pavia; ⁵Istituti Clinici Scientifici Maugeri IRCCS, Gastroenterology Unit of Pavia Institute, Pavia, Italy.

  Società Italiana di Reumatologia

  https://doi.org/10.4081/reumatismo.2025.2026

  133

• PO:10:153 | Isolated sarcoidosis of the parotid gland: a rare case of unilateral presentation Irene Carlino¹, Giorgio Carlino², Silvia Lombardo³, Luigi Gennari¹ | ¹Internal Medicine Unit, Department of Medicine Surgery and Neuroscience, University of Siena; ²ASL Lecce, Rheumatology Service DSS Casarano-Gallipoli-Gagliano del Capo, Gallipoli (LE); ³ASL Lecce, DSS Gagliano del Capo, Ugento (LE); Italy

  Società Italiana di Reumatologia

  https://doi.org/10.4081/reumatismo.2025.2147

  154

• PO:10:154 | Pudendal nevralgia as an unusual presenting symptom of axial spondyloarthritis Benedetta Bongiovanni¹, Gabriele Amati¹, Gilda Sandri^1|2, Giovanni Ciancio², Dilia Giuggioli^1|2 | ¹Struttura complessa di Reumatologia, azienda ospedaliera universitaria Policlinico di Modena; ²Cattedra di Reumatologia, università degli studi di Modena e Reggio Emilia, Modena, Italy

  Società Italiana di Reumatologia

  https://doi.org/10.4081/reumatismo.2025.2148

  163

• PO:10:155 | Etanercept-induced lupus in a patient with rheumatoid arthritis: diagnostic challenges and multidisciplinary therapeutic approach Camilla Riboldi^1|2, Claudia Iannone^1|2, Maria Gerosa^1|2, Roberto Felice Caporali^1|2 | ¹ASST G. Pini-CTO, U.O.C. di Clinica Reumatologica, Milano; ²Dipartimento di Scienze Cliniche e di Comunità, Università degli Studi di Milano, Italy

  Società Italiana di Reumatologia

  https://doi.org/10.4081/reumatismo.2025.2149

  141

• PO:10:157 | Sjögren’s syndrome with cryoglobulinemia associated with POEMS syndrome Andrea Mazzon¹, Elena Bianchi¹, Virginia Berlengiero¹, Luca Cantarini¹, Bruno Frediani¹, Enrico Selvi¹ | ¹Azienda Ospedaliera Universitaria Senese Le Scotte, Siena, Italy

  Società Italiana di Reumatologia

  https://doi.org/10.4081/reumatismo.2025.2150

  158

• PO:11:158 | Osteomyelitis of the jaw: a rare mimick of giant cell arteritis Laura Gigante¹, Giovanni B. Canestrari¹, Olga Addimanda¹, Francesca Bergossi¹, Angela Buffa¹, Francesco Cianci¹, Daniela Chiarini¹, Niccolò Girolimetto¹, Daniele Lini¹, Luca Magnani¹, Mirco Magnani¹, Erika Meleddu¹, Francesca Pignataro¹, Sofia Testoni¹, Alarico Ariani¹, Rita Mulè¹, Elisa Rossi¹, Enrica Vandelli¹, Gentiana Vukatana¹, Antonella Gamberini¹, Massimo Reta¹ | ¹UO interaziendale Medicina Interna ad Indirizzo Reumatologico - AUSL Bologna - AOSP Sant'Orsola Bologna, Italy

  Società Italiana di Reumatologia

  https://doi.org/10.4081/reumatismo.2025.2151

  143

• PO:11:162 | DRESS syndrome: a case treated with mepolizumab Alessandro Belotti Masserini¹, Stefania Bertocchi¹, Eleonora Bruschi¹, Silvia Breda¹, Valeria Rossi¹, Elide Lupi¹, Tania Ubiali¹, Fabrizio Angeli¹, Massimiliano Limonta¹ | ¹ASST Papa Giovanni XXIII, Bergamo, Italy

  Società Italiana di Reumatologia

  https://doi.org/10.4081/reumatismo.2025.2152

  173

• PO:11:165 | Clinical mimicry and therapeutic challenge: A Case of Rapidly Progressive Mixed Connective Tissue Disease Elena Maria Di Virgilio¹, Elisabetta Chessa², Valentina Ibba², Cosimina Matulli², Jessica Sorgia¹, Andrea Pace¹, Matteo Piga^1|2, Alberto Cauli^1|2 | ¹Università degli studi di Cagliari-Reumatologia, Cagliari, Italy; ²Struttura complessa di Reumatologia- AOU Cagliari, Cagliari, Italy

  Società Italiana di Reumatologia

  https://doi.org/10.4081/reumatismo.2025.2311

  39

• PO:11:167 | Subtle symptoms masking a challenging diagnosis: a clinical case of intestinal vasculitis in systemic lupus erythematosus Ilaria Pace¹, Giulia Rizzo¹, Elisabetta Chessa², Davide Corradini¹, Roberta Origa¹, Valentina Ibba², Alberto Floris^1|2, Alberto Cauli^1|2, Matteo Piga^1|2 | ¹Sapienza Università di Roma; ²SC Reumatologia, AOU Cagliari, Cagliari, Italy 

  Società Italiana di Reumatologia

  https://doi.org/10.4081/reumatismo.2025.2153

  217

• PO:11:170 | When Paget Meets Inflammatory Back Pain: A Diagnostic Dilemma Between Bone Remodeling and Spondyloarthritis Marco Capodiferro¹, Giuseppe Lopalco¹, Giulia Righetti², Gianluigi Della Corte², Patrizia Suppressa², Florenzo Iannone¹, Fabio Cacciapaglia^1|2 | ¹Unit of Rheumatology, Department of Precision and Regenerative Medicine, Area Jonica DiMePRe-J, University of Bari, Italy; ²Miulli General Hospital Acquaviva - Department of Medicine and Surgery, LUM F. De Gennaro University, Casamassima, Bari, Acquaviva delle Fonti, Italy

  Società Italiana di Reumatologia

  https://doi.org/10.4081/reumatismo.2025.2312

  47

• PO:11:171 | Subcutaneous tocilizumab use in a young-onset mixed connective tissue disease patient with multiple treatment failures Rhaysa Araujo Mousinho¹, Elide Lupi², Massimiliano Limonta² | ¹Clinica di Reumatologia, Dipartimento di Medicina and ²Istituto di Anatomia Patologica, Dipartimento di Medicina di Laboratorio, Osp. S. M. della Misericordia, Università di Udine, Italy

  Società Italiana di Reumatologia

  https://doi.org/10.4081/reumatismo.2025.2154

  146

• PO:11:172 | Not all vasculitis look the same: a difficult diagnosis Marta Arese^1|2, Miriam Perino^1|2, Sofia Aliprandi^1|2, Antonella Murgo², Maria Gerosa^1|2, Roberto Felice Caporali^1|2 | ¹UOC Reumatologia AOR San Carlo, Potenza; ²Reumatologia Clinica, ASST Gaetano Pini-CTO, Milano, Italy

  Società Italiana di Reumatologia

  https://doi.org/10.4081/reumatismo.2025.2155

  130

• PO:11:175 | Dermatomyositis and immunosuppressant treatment: a case of Staphylococcus aureus pneumonia in a hospitalized patient Simona Fichera¹, Andrea Cito¹, Martina Vigilia¹, Maria Morrone¹, Teresa Caferri¹, Crescenzio Scioscia¹, Simone Perniola¹, Giuseppe Lopalco¹, Florenzo Iannone¹. | ¹Unit of Rheumatology, Department of Precision and Regenerative Medicine, Area Jonica, University of Bari, Bari, Italy.

  Società Italiana di Reumatologia

  https://doi.org/10.4081/reumatismo.2025.2027

  139

• PO:12:177 | Systemic inflammation and QTc interval prolongation in new-onset polymyalgia rheumatica: the effect of corticosteroid therapy Anna Colangelo¹, Riccardo Accioli², Viola Salvini², Francesco Tromby¹, Giulia Cruciani¹, Martina Nicchi¹, Biancamaria Pianese¹, Francesca Lalli¹, Anna Cantore², Caterina Antonini¹, Decoroso Verrengia², Andrea Castellucci¹, Giacomo Cafaro¹, Carlo Perricone¹, Roberto Gerli¹, Pietro Enea Lazzerini², Elena Bartoloni¹ | ¹SC Reumatologia. Università di Perugia, Italy; ²Dipartimento di Scienze Mediche, Università di Siena, Italy

  Società Italiana di Reumatologia

  https://doi.org/10.4081/reumatismo.2025.2313

  36

• PO:12:178 | Don't count your chickens before they hatch! Analysis of cardiovascular definitions in studies on rheumatic diseases: a systematic literature review Laura Pezzoni¹, Silvia Sirotti^1|2, Georgios Filippou^1|2, Piercarlo Sarzi Puttini^1|2, Greta Pellegrino^1|2. | ¹Università degli Studi di Milano, Milano; ²IRCCS Ospedale Galeazzi Sant'Ambrogio, Milano, Italy.

  Società Italiana di Reumatologia

  https://doi.org/10.4081/reumatismo.2025.2028

  143

• PO:12:179 | Cardiovascular outcomes of treat-to-target urate-lowering therapy in gout: emulated target trials Edoardo Cipolletta¹, Davide Rozza², Abhishek Abhishek³ | ¹Azienda Ospedaliero Universitaria delle Marche, Ancona, Italy; ²Società Italiana di Reumatologia, Milano, Italy; ³University of Nottingham Nottingham, United Kingdom

  Società Italiana di Reumatologia

  https://doi.org/10.4081/reumatismo.2025.2314

  39

• PO:12:180 | Echocardiographic screening of pulmonary hypertension in a multidisciplinary cohort of patients with interstitial lung disease Lorenzo Mattia Bianchessi¹, Veronica Piccin¹, Federica Sabatelli¹, Lorenzo Cavagna¹, Giovanni Zanframundo¹, Domenicafederica Briganti², Mauro Acquaro³,  Stefano Ghio³, Domenico Sorace¹, Valentina Vertui², Ilaria Giana², Andrea Patanè³, Veronica Codullo¹ | ¹UOC Reumatologia, Fondazione IRCCS Policlinico S. Matteo, Pavia; ²Centro Trapianti, Fondazione IRCCS Policlinico San Matteo, Pavia; ³UOC Cardiologia, Fondazione IRCCS Policlinico San Matteo, Pavia, Italy

  Società Italiana di Reumatologia

  https://doi.org/10.4081/reumatismo.2025.2156

  152

• PO:12:183 | Acute effect of anti-TNF therapy on atrioventricular conduction in chronic inflammatory arthritis: a prospective cohort study Viola Salvini¹, Riccardo Accioli¹, Anna Cantore¹, Fabio Salvadori¹, Enrico Selvi², Virgina Berlengerio², Maurizio Acampa³, Alessandra Cartocci¹, Decoroso Verrengia¹, Kateryna Miedviedieva¹, Sciaila Bernardini¹, Michele Voglino¹, Maurizio Bicchi¹, Daniela Merlotti¹, Stefania Bisogno¹, Pier Leopoldo Capecchi¹, Pietro Enea Lazzerini¹ | ¹Division of Internal Medicine, Electroimmunology Unit, University Hospital of Siena, Italy; ²Division of Rheumatology, University Hospital of Siena, Italy; ³Stroke Unit, University Hospital of Siena, Italy

  Società Italiana di Reumatologia

  https://doi.org/10.4081/reumatismo.2025.2315

  50

• PO:12:184 | Atrioventricular conduction in chronic inflammatory arthritis: enhanced assessment by new electrocardiographic parameters Riccardo Accioli¹, Viola Salvini¹, Anna Cantore¹, Fabio Salvadori¹, Enrico Selvi², Virgina Berlengiero², Maurizio Acampa³, Alessandra Cartocci¹, Kateryna Miedviedieva¹, Decoroso Verrengia¹, Sciaila Bernardini¹, Michele Voglino¹, Giovanni Donati¹, Silvia Petri¹, Severino Gallo¹, Stefania Bisogno¹, Pier Leopoldo Capecchi¹, Pietro Enea Lazzerini¹ | ¹Division of Internal Medicine, Electroimmunology Unit, University Hospital of Siena, Italy; ²Division of Rheumatology, University Hospital of Siena, Italy; ³Stroke Unit, University Hospital of Siena, Italy

  Società Italiana di Reumatologia

  https://doi.org/10.4081/reumatismo.2025.2316

  30

• PO:12:186 | Clinical, functional, and microvascular features in the early diagnosis and management of pulmonary hypertension in systemic sclerosis: the importance of multimodal screening strategies Irene Carlino¹, Stefania Bisogno¹, Alberto Palazzuoli², Luigi Gennari¹ | ¹U.O.C. Reumatologia, Dipartimento di Scienze Mediche, Chirurgiche e Neuroscienze, Università di Siena, A.O.U. Senese; ²Azienda Sanitaria Locale, Novara, Italy

  Società Italiana di Reumatologia

  https://doi.org/10.4081/reumatismo.2025.2157

  138

• PO:12:187 | Maternal Hypertensive Disorders in Pregnant Women with Rheumatic Diseases and long-term Cardiovascular Outcomes: preliminary data of a single centre experience Margherita Rinaldi¹, Paolo Semeraro¹, Francesca Crisafulli¹, Matteo Filippini², Maria Grazia Lazzaroni¹, Cecilia Nalli¹, Liala Moschetti¹, Marco Taglietti², Chiara Loardi³, Rossana Orabona³, Francesca Ramazzotto³, Sonia Zatti³, Laura Andreoli¹, Angela Tincani¹, Micaela Fredi¹, Ilaria Cavazzana¹, Franco Franceschini¹ | ¹Department of Clinical and Experimental Sciences, University of Brescia, Italy; ²Rheumatology and Clinical Immunology, ASST Spedali Civili of Brescia, ERN-ReCONNET Center Brescia, Italy; ³Gynaecology and Obstetrics Unit ASST Spedali Civili di Brescia, Italy

  Società Italiana di Reumatologia

  https://doi.org/10.4081/reumatismo.2025.2317

  34

• PO:13:188 | Menstrual alterations among women with rheumatoid arthritis: a comparative study across treatment modalities with focus on JAK inhibitors Angelica Napoletano¹, Francesca Arezzo², Marco Fornaro¹, Giuseppe Lopalco¹, Gennaro Cormio², Vincenzo Venerito¹, Florenzo Iannone¹. | ¹University of Bari, Rheumatology Unit Department of Precision and Regenerative Medicine, Jonica Area, Bari; ²Gynecologic Oncology, IRCCS Istituto Tumori Giovanni Paolo II, Bari, Italy.

  Società Italiana di Reumatologia

  https://doi.org/10.4081/reumatismo.2025.2029

  325

• PO:13:189 | Greater impact of psoriatic arthritis in females: is this mediated primarily by disease activity? Roberta Masnata¹, Valentina Boni¹, Giusy Peluso¹, Giulia Calabrese¹, Enrico De Lorenzis¹, Gerlando Natalello¹, Maria Antonietta D'Agostino¹, Augusta Ortolan¹. | ¹UOC Reumatologia e Immunologia Clinica- Fondazione Policlinico Agostino Gemelli IRCCS-Università Cattolica Sacro Cuore, Roma, Italy.

  Società Italiana di Reumatologia

  https://doi.org/10.4081/reumatismo.2025.2030

  147

• PO:14:193 | Dapirolizumab Pegol Demonstrated Significant Improvement in Systemic Lupus Erythematosus Disease Activity: Efficacy and Safety Results of a Phase 3 Trial Megan EB Clowse¹, Marta Mosca², David A Isenberg³, Joan T Merrill⁴, Thomas Dörner⁵, Michelle Petri⁶, Edward M Vital^7|8, Eric F Morand⁹, Teri Jimenez¹⁰, Stephen Brookes¹¹, Janine Gaiha-Rohrbach¹², Christophe Martin¹³, Annette Nelde¹⁴, Christian Stach¹⁵ | ¹Duke University - Division of Rheumatology and Immunology Durham, USA; ²University of Pisa - Rheumatology Unit, Department of Clinical and Experimental Medicine Pisa, Italy; ³University College London - Department of Ageing, Rheumatology and Regenerative Medicine, Division of Medicine London, United Kingdom; ⁴Oklahoma Medical Research Foundation Oklahoma City, USA; ⁵Charité Universitätsmedizin Berlin - Department of Medicine/Rheumatology and Clinical Immunology Berlin Germany; ⁶Johns Hopkins University School of Medicine Baltimore, USA; ⁷University of Leeds - Leeds Institute of Rheumatic and Musculoskeletal Medicine Leeds, United Kingdom; ⁸Leeds Teaching Hospitals NHS Trust - NIHR Leeds Biomedical Research Centre Leeds, United Kingdom; ⁹Monash University - Centre for Inflammatory Diseases Melbourne, Australia; ¹⁰UCB Raleigh, USA; ¹¹Biogen Maidenhead, United Kingdom; ¹²Biogen Cambridge, USA; ¹³UCB Slough, United Kingdom; ¹⁴Biogen Baar, Switzerland; ¹⁵UCB Monheim am Rhein, Germany

  Società Italiana di Reumatologia

  https://doi.org/10.4081/reumatismo.2025.2318

  44

• PO:14:194 | The CORAL Study: Complement levels during pregnancy in prospectively followed systemic Lupus erythematosus patients Irene Cecchi¹, Massimo Radin¹, Alice Barinotti¹, Francesca Crisafulli², Laura Andreoli², Cecilia Beatrice Chighizola³, Savino Sciascia¹, On Behalf Of The Coral Study Group¹ | ¹Università di Torino, Italy; ²Università di Brescia, Italy; ³Università di Milano, Italy

  Società Italiana di Reumatologia

  https://doi.org/10.4081/reumatismo.2025.2319

  16

• PO:14:195 | Real-world effectiveness of anifrolumab in achieving treatment targets and reducing systemic lupus erythematosus disease burden: 6-month interim analysis of the REVEAL study Chiara Cardelli^1|2, Chiara Tani¹, Luca Moroni³, Filippo Vesentini⁴, Francesca Bottazzi⁵, Micaela Fredi⁶, Ettore Silvagni⁷, Matteo Piga⁸, Flavia Riccio⁹, Fulvia Ceccarelli¹⁰, Ginevra De Marchi¹¹, Edoardo Biancalana¹², Gianluca Moroncini¹³, Rita Mulè¹⁴, Mariele Gatto¹⁵, Laura Coladonato¹⁶, Paola Conigliaro¹⁷, Maria Gerosa¹⁸, Andrea Picchianti Diamanti¹⁹, Benedetta Bianchi²⁰, Federica Maiolini²⁰, Michela Gasparotto²⁰, Serena Guiducci²⁰, Maria Ilenia De Andres²⁰, Alberto Lo Gullo²⁰, Silvia Noviello²⁰, On Behalf Of The Reveal Investigators²⁰, Marta Mosca¹. | ¹Rheumatology Unit, Department of Clinical and Experimental Medicine, University of Pisa, Pisa; ²Department of Medical Biotechnologies, University of Siena, Siena; ³Unit of Immunology, Rheumatology, Allergy and Rare Diseases, IRCCS San Raffaele Hospital, Milano; ⁴Rheumatology Unit, Department of Medicine, University of Padua, Padova; ⁵Department of Internal Medicine and Therapeutics, University of Pavia, Pavia; ⁶Rheumatology and Clinical Immunology, Department of Clinical and Experimental Sciences, University of Brescia, Brescia; ⁷Section of Rheumatology, Department of Medical Sciences, University of Ferrara; AOU Sant'Anna, Ferrara; ⁸Rheumatology Unit, Department of Medical Sciences and Public Health, University of Cagliari, Cagliari;  ⁹Department of Precision Medicine, University of Campania Luigi Vanvitelli, Napoli; ¹⁰Rheumatology Unit, Dept. of Clinical Internal, Anesthesiological and Cardiovascular Sciences, Sapienza University of Rome, Roma; ¹¹Division of Rheumatology, Department of Medicine, Azienda Sanitaria Universitaria del Friuli Centrale, Udine; ¹²Internal Interdisciplinary Medicine Unit, Department of Experimental and Clinical Medicine, University of Florence, Firenze; ¹³Department of Clinical and Molecular Sciences, Marche Polytechnic University, Ancona; ¹⁴Azienda Ospedaliero-Universitaria di Bologna, Internal Medicine and Rheumatology, IRCCS S. Orsola Malpighi, Bologna; ¹⁵Academic Rheumatology Centre, Department of Clinical and Biological Sciences, University of Turin; AO Mauriziano, Torino; ¹⁶Rheumatology Unit, Department of Precision and Regenerative Medicine and Ionian Area, University of Bari, Bari; ¹⁷Rheumatology, Allergology and Clinical Immunology, Department of Systems Medicine, Tor Vergata University of Rome, Roma; ¹⁸Clinical Rheumatology, ASST Gaetano Pini CTO; Department of Clinical Sciences and Community Health, University of Milano, Milano; ¹⁹Department of Clinical and Molecular Medicine, Sapienza University of Rome; AOU Sant'Andrea, Roma, Italy; ²⁰Italian REVEAL Study Group Italy, Italy

  Società Italiana di Reumatologia

  https://doi.org/10.4081/reumatismo.2025.2031

  162

• PO:14:196 | Photosensitivity in Lupus Erythematosus: The Patients' Perspective in a National Survey Marianna Salis¹, Elisabetta Chessa², Alessandra Oliva¹, Marta Paola Pireddu¹, Fabio Congiu¹, Giulia Rizzo¹, Elena Ragusa¹, Alberto Cauli^1|2, Laurent Arnaud³, Matteo Piga^1|2 | ¹Università degli Studi di Cagliari, Italy; ²Azienda Ospedaliera Universitaria di Cagliari, Unità Operativa Complessa di Reumatologia Cagliari, Italy; ³Strasbourg University and Academic Hospitals Strasbourg, France

  Società Italiana di Reumatologia

  https://doi.org/10.4081/reumatismo.2025.2320

  18

• PO:14:197 | Safety of biologic and conventional immunosuppressants in an Italian cohort of patients with systemic lupus erythematosus: a longitudinal analysis from the Lupus Italian Registry pharmacoepidemiologic study promoted by the Italian Society of Rheumatology Davide Rozza¹, Carlo Alberto Scirè^1|2, Paola Conigliaro³, Giacomo Emmi⁴, Laura Coladonato⁶, Salvatore Scarpato⁷, Luca Iaccarino⁸, Serena Guiducci⁹, Giulia Pazzola¹⁰, Francesca Romana Spinelli¹¹, Micol Frassi¹², Ilaria Cavazzana¹², Chiara Scirocco¹³, Valeria Orefice¹³, Immacolata Prevete¹³, Alessandra Bortoluzzi¹⁴, Marcello Govoni¹⁴, Elena Bartoloni¹⁵, Luca Moroni¹⁶, Giuseppe Alvise Ramirez¹⁶, Valentina Canti¹⁶, Giorgio Pettiti¹⁷, Maria Chiara Ditto¹⁸, Enrico Fusaro¹⁸, Marta Mosca¹⁹, Lorenzo Cavagna²⁰, Fabrizio Conti¹¹, Andrea Doria⁸, Gian Domenico Sebastiani¹³, Sperimentatori Gruppo Lire⁵ | ¹Centro Studi della Società Italiana di Reumatologia, Milano; ²Dipartimento di Medicina e Chirurgia, Università degli Studi di Milano-Bicocca, Monza; ³Università di Roma Tor Vergata; ⁴Dipartimento di Scienze Mediche, Chirurgiche e della Salute, Università di Trieste; ⁵https://redcap.reumatologia.it/surveys/?s=LWL7WJM4KHDR97CC; ⁶Dip di Medicina di Precisione e Rigenerativa e area Jonica, Bari; ⁷Azienda Sanitaria Locale ^ASL Salerno; ⁸Università degli Studi di Padova; ⁹SOD Reumatologia, Dipartimento di Medicina Sperimentale e Clinica, Università degli Studi di Firenze; ¹⁰Arcispedale Santa Maria Nuova Reggio Emilia; ¹¹Università degli Studi di Roma La Sapienza; ¹²Spedali Civili di Brescia; ¹³Azienda Ospedaliera San Camillo Forlanini, Roma; ¹⁴Azienda Ospedaliera Universitaria Sant'Anna, Ferrara; ¹⁵SC Reumatologia, Dipartimento di Medicina e Chirurgia, Università di Perugia; ¹⁶IRCCS Ospedale San Raffaele, Milano; ¹⁷Azienda Ospedaliera S. Croce e Carle, Cuneo; ¹⁸AOU Citta' della Salute e della Scienza di Torino; ¹⁹AOU Santa Chiara, Pisa; ²⁰Università di Pavia, Italy

  Società Italiana di Reumatologia

  https://doi.org/10.4081/reumatismo.2025.2158

  145

• PO:14:198 | Temporal Trends in LLDAS and DORIS Achievement in SLE: Impact of Evolving International Recommendations Laura Coladonato¹, Marco Fornaro¹, Angelica Napoletano¹, Daniele Catamerò¹, Giuseppe Lopalco¹, Florenzo Iannone¹ | ¹UOC Reumatologia, Policlinico di Bari, DiMePre-J Bari, Italy

  Società Italiana di Reumatologia

  https://doi.org/10.4081/reumatismo.2025.2321

  26

• PO:14:199 | Preliminary data of a multicentric study on safety and efficacy of assisted reproductive techniques in pregnant women with systemic autoimmune diseases Valentina Canti¹, Maria Bernadette Cilona¹, Giuditta Gorgone¹, Federica Pasi¹, Antonia Calligaro², Francesca Ruffilli³, Francesca Crisafulli⁶, Maria Tonello², Eleonora Giacobbe⁴, Alba Chiara Pozzi⁶, Maria Chiara Gerardi⁴, Melissa Padovan³, Emanuele Bizzi⁵, Enrico Papaleo¹, Beatrice Maranini³, Marcello Govoni³, Massimiliano Epis⁴, Angela Tincani⁶, Andrea Doria², Patrizia Rovere Querini¹ | ¹IRCCS Ospedale San Raffaele and VitaSalute San Raffaele Milano, Italy; ²Rheumatology Unit, Departement of Medicine, University Hospital of Padua Padova, Italy; ³Rheumatology Unit, Azienda Ospedaliero Universitaria S. Anna Ferrara, Department of Medical Sciences, University of Fe Ferrara, Italy; ⁴ASST Grande Ospedale Metropolitano Niguarda Milano, Italy; ⁵Internal Medicine, Fatebenefratelli Hospital Milano, Italy; ⁶Rheumatology and Immunology Unit, ASST Spedali Civili Brescia e Università degli Studi di Brescia, Italy

  Società Italiana di Reumatologia

  https://doi.org/10.4081/reumatismo.2025.2322

  23

• PO:14:200 | Placental markers of angiogenesis in pregnant women with antiphospholipid syndrome: predictive role of SFLT-1, PLGF, and uterine artery doppler in preeclampsia Maria Bernadette Cilona¹, Valentina Canti¹, Martina Beschi², Federica Pasi³, Serena Girardelli³, Mirko Pozzoni³, Maria Teresa Castiglioni³, Paolo Cavoretto³, Patrizia Rovere-Querini^1|2 | ¹Unit of Internal Medicine and Division of Immunology, Transplantation and Infectious diseases, IRCCS San Raffaele Hospital Milan, Italy; ²Vita-Salute San Raffaele University Milan, Italy; ³Department of Obstetrics and Gynecology, IRCCS San Raffaele Scientific Institute Milan, Italy

  Società Italiana di Reumatologia

  https://doi.org/10.4081/reumatismo.2025.2323

  12

• PO:14:201 | Olfactory Assessment in Patients with Systemic Lupus Erythematosus: Correlation with Clinical, Serological, and Imaging Markers Lorenza Bruno¹, Giacomo Cafaro¹, Marta Di Berardino¹, Roberto Dal Pozzolo¹, Anna Colangelo¹, Francesco Tromby¹, Martina Nicchi¹, Giulia Cruciani¹, Biancamaria Pianese¹, Roberto Gerli¹, Elena Bartoloni Bocci¹, Carlo Perricone¹ | ¹Università degli Studi di Perugia, Italy

  Società Italiana di Reumatologia

  https://doi.org/10.4081/reumatismo.2025.2324

  31

• PO:14:202 | Use of anifrolumab in the treatment of the hematological manifestations of systemic lupus erythematosus: a single-centre case series Gaia Ferracane^1|2, Jessika Dichiara^1|2, Elena Manna^1|2, Lorenzo Mattia Bianchessi^1|2, Giovanni Zanframundo^1|2, Serena Bugatti^1|2, Veronica Codullo^1|2, Lorenzo Cavagna^1|2, Francesca Bottazzi^1|2 | ¹Department of Internal Medicine and Therapeutics, Università di Pavia; ²Division of Rheumatology, IRCCS Policlinico San Matteo, Pavia, Italy

  Società Italiana di Reumatologia

  https://doi.org/10.4081/reumatismo.2025.2159

  195

• PO:14:203 | Impact of anifrolumab on depressive symptoms in systemic lupus erythematosus: results from a single-centre prospective observational study Luca Moroni¹, Biancamaria Venerandi¹, Maria Cilona¹, Anna Vivona¹, Gabriele Gallina¹, Giovanni Benanti¹, Enrica Bozzolo¹, Giuseppe Ramirez¹, Marco Matucci-Cerinic¹, Lorenzo Dagna¹. | ¹U.O. di Immunologia, Reumatologia, Allergologia e Malattie Rare - IRCCS Ospedale San Raffaele, Milano, Italy.

  Società Italiana di Reumatologia

  https://doi.org/10.4081/reumatismo.2025.2032

  134

• PO:14:204 | Risk stratification in systemic lupus erythematosus patients: improving the performances of a prediction model Lucia Lanzo¹, Silvia Laura Bosello¹, Livia Lilli², Laura Antenucci², Carlotta Masciocchi², Marco Gorini³, Gabriella Castellino³, Luca Petricca¹, Maria Rita Gigante¹, Vivianaantonella Pacucci¹, Pier Giacomo Cerasuolo¹, Silvia Piunno¹, Francesco Cristiano¹, Cesare Gavotti¹, Pier Luigi Rizzuti¹, Rebecca Ventura¹, Jacopo Lenkowicz², Alfredo Cesario², Stefano Patarnello², Maria Antonietta D'Agostino¹. | ¹UOC di Reumatologia e Immunologia clinica - Fondazione Policlinico Universitario A. Gemelli IRCSS, UCSC, Roma, Italy; ²Fondazione Policlinico Universitario Agostino Gemelli IRCSS, Roma, Italy; ³AstraZeneca MIND, Milano, Italy.

  Società Italiana di Reumatologia

  https://doi.org/10.4081/reumatismo.2025.2033

  155

• PO:14:205 | Primary antiphospholipid antibody syndrome: association between new classification criteria manifestations and a higher-risk disease phenotype Sara Ferrigno¹, Vittorio Forte², Marco Panetta¹, Sergio Lisena¹, Giorgia Ranucci², Luigi De Marco¹, Elisabetta Greco¹, Alberto Bergamini¹, Maria Sole Chimenti¹, Paola Conigliaro¹. | ¹Rheumatology, allergology and clinical immunology, Department of Systems Medicine, University of Rome Tor Vergata, Rome, Italy; ²Hematology, Department of Biomedicine and Prevention, University of Rome Tor Vergata, Rome, Italy.

  Società Italiana di Reumatologia

  https://doi.org/10.4081/reumatismo.2025.2034

  158

• PO:14:206 | Factors impacting subjective cognitive impairment in systemic lupus erythematosus patients: clearing away the lupus brain fog Elisabetta Chessa¹, Marta Paola Pireddu², Fabio Congiu², Giulia Rizzo², Cristina Serafini³, Elena Ragusa², Alberto Cauli^1|2, Matteo Piga^1|2. | ¹SC Reumatologia- AOU Cagliari, Cagliari, Italy; ²Dipartimento di Scienze Mediche e Sanità Pubblica, Università di Cagliari, Cagliari, Italy; ³PO Sirai - Unità di Nefrologia e Dialisi, Carbonia (CA), Italy.

  Società Italiana di Reumatologia

  https://doi.org/10.4081/reumatismo.2025.2035

  153

• PO:14:207 | Nailfold capillaroscopy in systemic lupus erythematosus: microvascular alterations and their clinical relevance Giulia Cassone¹, Filippo Santoro², Maria Grazia Malandra², Bruno Biasi², Elena Vanni², Caterina Vacchi¹, Alesandra Carobbio³, Dilia Giuggioli^1|2. | ¹Reumatologia, Azienda Ospedaliero-Universitaria Policlinico di Modena, Modena, Italy; ²Università di Modena e Reggio Emilia, Modena, Italy; ³Dipartimento di Scienze Mediche e Chirurgiche Materno-Infantili e dell'Adulto, Univeristà di Modena e Reggio Emilia, Modena, Italy.

  Società Italiana di Reumatologia

  https://doi.org/10.4081/reumatismo.2025.2036

  142

• PO:15:208 | Impact of disease control on organ damage accrual in patients with systemic lupus erythematosus with and extra-renal flares: a 12-month single-center longitudinal study Giorgia Capozzo¹, Marco Oliva¹, Giancarlo Cascarano¹, Chiara Cardelli¹, Dina Zucchi¹, Chiara Stagnaro², Viola Signorini², Elena Elefante², Chiara Tani¹, Marta Mosca¹. | ¹Università di Pisa, Dipartimento di Medicina Clinica e Sperimentale, Pisa, Italy; ²Azienda Ospedaliero Universitaria Pisana, U.O. Reumatologia, Pisa, Italy.

  Società Italiana di Reumatologia

  https://doi.org/10.4081/reumatismo.2025.2037

  144

• PO:15:209 | Attainment of remission or lupus low disease activity state in single center Lupus Clinic Paola Tedoldi^1|2, Silvia Ebe Lucia Della Pina^1|2, Claudia Barison^1|2, Chiara Orlandi^1|2, Cecilia Nalli¹, Micaela Fredi², Ilaria Cavazzana^1|2, Franco Franceschini^1|2 | ¹Rheumatology and Clinical Immunology Unit- ERN ReCONNET, ASST Spedali Civili of Brescia Brescia, Italy; ²Department of Clinical and Experimental Sciences, University of Brescia Brescia, Italy

  Società Italiana di Reumatologia

  https://doi.org/10.4081/reumatismo.2025.2325

  37

• PO:15:212 | Anifrolumab induces a rapid improvement in joint inflammation in Systemic Lupus Erythematosus patients: an ultrasonographic study Valeria Moretti, Fulvia Ceccarelli, Claudia Ciancarella, Valerio Fiorilli, Francesca Romana Spinelli, Fabrizio Conti | Sapienza Università di Roma, Italy

  Società Italiana di Reumatologia

  https://doi.org/10.4081/reumatismo.2025.2326

  13

• PO:15:214 | Identification of SLE patients with high-levels Type 2 SLE through the polysymptomatic distress scale (PSD): correlations with other PROs and differences in clinical phenotypes in a multicentric cohort Micaela Fredi^1|2, Giorgia Gozzoli^1|2, Federica Bonaso^1|2, Silvia Ebe Della Pina^1|2, Claudia Barison^1|2, Irene Lorenzini², Anna Mattiuzzo², Raffaele Pericotti², Marcelo Neto³, Sofia Avedo⁴, Clàudia Oliveira⁴, Luis Sousa Ines³, Franco Franceschini^1|2 | ¹Rheumatology and Clinical Immunology, ASST Spedali Civili of Brescia, ERN-ReCONNET Center, Brescia, Italy; ²Department of Clinical and Experimental Sciences, University of Brescia, Brescia, Italy; ³Rheumatology Department, Centro Hospitalar Universitário de Coimbra - ULS Coimbra, Coimbra, Portugal; ⁴Rheumatology Department, ULS Aveiro, Aveiro, Portugal

  Società Italiana di Reumatologia

  https://doi.org/10.4081/reumatismo.2025.2327

  12

• PO:15:215 | Evaluating the Prognostic Value of Modified NIH Indices and Total Renal Chronicity Score in Lupus Nephritis: a single center retrospective analysis Alessandra Ida Celia¹, Andrea Ascione², Bruna Cerebelli², Martina Leopizzi², Cristiano Alessandri¹, Francesca Romana Spinelli¹, Fabrizio Conti¹ | ¹Reumaologia, Scienze Cliniche internistiche, anestesiologiche e cardiovascolari, Università La Sapienza di Roma, Italy; ²Anatomia patologica, Dipartimento di Scienze biotecnologiche medico-chirurgiche, Università La Sapienza di Roma, Italy

  Società Italiana di Reumatologia

  https://doi.org/10.4081/reumatismo.2025.2328

  13

• PO:15:216 | Safety and Efficacy of a single dose of Rituximab to manage Pregnancy-Related Severe Flare of Systemic Lupus Erythematosus: A Case Report Eugenio Capparelli¹, Daniela Bompane¹, Eleonora Zaccara¹, Laura Castelnovo¹, Antonio Tamburello¹, Antonino Mazzone², Paola Faggioli¹ | ¹UOC Reumatologia, ASST Ovest Milanese, Legnano, Milano, Italy; ²UOC Medicina Interna, ASST Ovest Milanese, Legnano, Milano, Italy

  Società Italiana di Reumatologia

  https://doi.org/10.4081/reumatismo.2025.2329

  27

• PO:15:217 | Improved efficacy and safety outcomes in patients with systemic lupus erythematosus treated with belimumab vs. immunosuppressants, in addition to antimalarials and glucocorticoids: a post-hoc summary of five phase 3 trials Mariele Gatto¹, Karen H. Costenbader², Andreas Schwarting³, Julia Hn Harris⁴, Ciara O'Shea⁵, Roger A. Levy⁶, Andrea Doria⁷ | ¹Centro Accademico Reumatologia, Dipartimento Scienze Cliniche Biologiche, Università degli Studi Torino, Osp. Mauriziano, Italy; ²Brigham and Women's Hospital, Divisione di Reumatologia, Infiammazione e Immunità, Harvard Medical School, Boston, MA, USA; ³Università Johannes Gutenberg di Mainz, Centro medico universitario, Germany; ⁴GSK, Immunologia Biostatistica London, UK; ⁵GSK, Global Medical Affairs Reumatologia, Dublin, Ireland; ⁶GSK, Global Medical Affairs Collegeville, PA, USA; ⁷Divisione di Reumatologia, Dipartimento di Medicina, Università di Padova, Italy

  Società Italiana di Reumatologia

  https://doi.org/10.4081/reumatismo.2025.2160

  155

• PO:15:218 | Evaluation of leukocyte expression of ecto-nucleotidase in patients with systemic lupus erythematosus Luca Rapino¹, Simona Truglia¹, Fulvia Ceccarelli¹, Francesca Romana Spinelli¹, Silvia Mancuso¹, Giada La Spina¹, Hector Rincon Arvalo², Thomas Doerner², Ana Luisa Stefanski², Fabrizio Conti¹. | ¹La Sapienza Università di, Roma, - Dipartimento di Scienze Cliniche Internistiche Anestesiologiche e Cardiovascolare, Roma, Italy; ²Charité Universitätsmedizin - Department of Rheumatology and Clinical Immunology, Berlino, Germany.

  Società Italiana di Reumatologia

  https://doi.org/10.4081/reumatismo.2025.2038

  120

• PO:15:219 | Nailfold capillaroscopic abnormalities in systemic lupus erythematosus: comparison with healthy controls and clinical-immunological correlations. Preliminary data Chiara Orlandi^1|2, Alessia Loda², Cesare Tomasi^1|2, Silvia Ebe Lucia Della Pina^1|2, Claudia Barison^1|2, Cecilia Nalli¹, Ilaria Cavazzana^1|2, Micaela Fredi^1|2, Franco Franceschini^1|2. | ¹Rheumatology and Clinical Immunology Unit - ERN ReCONNET , ASST Spedali Civili of Brescia, Brescia, Italy; ²Department of Clinical and Experimental Sciences, University of Brescia, Brescia, Italy.

  Società Italiana di Reumatologia

  https://doi.org/10.4081/reumatismo.2025.2039

  125

• PO:15:220 | Outcomes of extra renal flares in systemic lupus erythematosus: longitudinal analysis of a monocentric cohort Marco Oliva¹, Giorgia Capozzo¹, Giancarlo Cascarano¹, Chiara Cardelli¹, Dina Zucchi¹, Angela Elia¹, Elena Elefante², Viola Signorini², Chiara Stagnaro², Chiara Tani¹, Marta Mosca¹. | ¹Rheumatology Unit, Department of Clinical and Experimental Medicine, University of Pisa, Pisa, Italy; ²Rheumatology Unit, AOUP, Pisa, Italy.

  Società Italiana di Reumatologia

  https://doi.org/10.4081/reumatismo.2025.2040

  136

• PO:15:221 | Proteins upregulated in thrombotic antiphospholipid syndrome link to platelet function in contrast with non-antiphospholipid-related thrombosis: insights from two systematic reviews Silvia Mancuso¹, Claudia Ciancarella¹, Luca Rapino¹, Simona Truglia¹, Cristiano Alessandri¹, Fabrizio Conti¹. | ¹Dipartimento di Scienze Cliniche Internistiche, Anestesiologiche e Cardiovascolari - Rheumatology Unit, Sapienza Univers, Roma, Italy.

  Società Italiana di Reumatologia

  https://doi.org/10.4081/reumatismo.2025.2041

  154

• PO:15:222 | Post-hoc analysis of the BeRLiSS-JS registry: efficacy of belimumab on thrombocytopenia Greta Hulej¹, Margherita Zen¹, Marisol Bracalenti¹, Francesca Bottazzi², Rossella De Angelis³, Giacomo Emmi⁴, Roberto Gerli⁵, Marcello Govoni⁶, Renato Lo Gullo⁷, Simone Negrini⁸, Luca Quartuccio⁹, Maurizio Rossini¹⁰, Carlo Salvarani¹¹, Paola Tomietto⁴, Angelo Vacca¹², Andrea Doria¹, Luca Iaccarino¹. | ¹Università degli Studi di Padova, Padova, Italy; ²Università degli Studi di Pavia, Pavia, Italy; ³Università Politecnica delle Marche, Ancona, Italy; ⁴Università degli Studi di Trieste, Trieste, Italy; ⁵Università degli Studi Perugia, Perugia, Italy; ⁶Università degli Studi di Ferrara, Ferrara, Italy; ⁷Università degli Studi di Catania, Catania, Italy; ⁸Università degli Studi di Torino, Torino, Italy; ⁹Università degli Studi di Udine, Udine, Italy; ¹⁰Università degli Studi di Verona, Verona, Italy; ¹¹Università degli Studi di Modena e Reggio Emilia, Modena, Italy; ¹²Università degli Studi di Bari .

  Società Italiana di Reumatologia

  https://doi.org/10.4081/reumatismo.2025.2042

  137

• PO:15:224 | Measuring disease activity in Systemic Lupus Erythematosus patients: SLE-DAS usefulness in real-life setting Valeria Moretti, Fulvia Ceccarelli, Claudia Ciancarella, Cristina Garufi, Alessandra Ida Celia, Silvia Mancuso, Angelica Gattamelata, Simona Truglia, Francesca Romana Spinelli, Cristiano Alessandri, Fabrizio Conti | La sapienza Università di Roma, Italy

  Società Italiana di Reumatologia

  https://doi.org/10.4081/reumatismo.2025.2330

  15

• PO:16:225 | Belimumab in refractory and/or non-criteria manifestations of antiphospholipid syndrome: ad interim analysis on Quality-of-Life changes from the BLAST trial Alessio Conti¹, Lois Ira Capulong¹, Irene Cecchi¹, Elena Rubini¹, Chiara Bova¹, Massimo Radin¹, Alice Barinotti¹, Beatrice Ala¹, Silvia Grazietta Foddai¹, Daniela Rossi¹, Roberta Fenoglio¹, Savino Sciascia¹ | ¹Centro di Eccellenza Universitario per le Malattie Nefrologiche, Reumatologiche e Rare, S.G.Bosco -ASL Città di Torino, Italy

  Società Italiana di Reumatologia

  https://doi.org/10.4081/reumatismo.2025.2331

  18

• PO:16:226 | Clinical Phenotypes of Systemic Lupus Erythematosus: An Exploratory Cluster Analysis in a Monocentric Cohort Richard Borrelli¹, Stefania Nicola¹, Federica Corradi¹, Iuliana Badiu¹, Luca Lo Sardo¹, Marzia Boem¹, Valentina Marmora¹, Simone Negrini¹, Luisa Brussino¹ | ¹SCDU Immunologia e Allergologia, AO Mauriziano, Dipartimento di Scienze Mediche, Università degli Studi di Torino, Italy

  Società Italiana di Reumatologia

  https://doi.org/10.4081/reumatismo.2025.2332

  17

• PO:16:227 | Anifrolumab for Systemic Lupus Erythematosus: Preliminary Safety and Efficacy Findings from the Italian Experience Paola Bizioli^1|2, Chiara Orlandi^1|2, Claudia Barison^1|2, Cesare Tomasi³, Alessia Caproli¹, Silvia Piantoni^1|2, Simona Signorini⁴, Emirena Garrafa⁴, Cecilia Nalli¹, Micol Frassi¹, Ilaria Cavazzana^1|2, Micaela Fredi^1|2, Franco Franceschini^1|2 | ¹Rheumatology and Clinical Immunology Unit - ERN ReCONNET, ASST Spedali Civili of Brescia, Italy; ²Department of Clinical and Experimental Sciences, University of Brescia, Italy; ³Department of Clinical and Experimental Sciences, University of Brescia, Italy; ⁴Laboratory of Clinical Chemistry, Department of Molecular and Translational Medicine, University of Brescia, Italy

  Società Italiana di Reumatologia

  https://doi.org/10.4081/reumatismo.2025.2333

  41

• PO:16:231 | Differential clinical features of systemic lupus erythematosus patients on biological therapies: insights from a monocentric cohort Pietro Francesco Pilo, Elisa Bellis, Claudia Garulli, Claudio Cruciani, Marta Saracco, Claudia Lomater, Elena Marucco, Gloria Crepaldi, Valeria Data, Annamaria Iagnocco, Mariele Gatto. | Academic Rheumatology Centre, Department of Clinical and Biological Sciences, University of Turin, AO Mauriziano, Torino, Italy.

  Società Italiana di Reumatologia

  https://doi.org/10.4081/reumatismo.2025.2043

  136

• PO:16:232 | Belimumab step-down dose spacing in patients with systemic lupus erythematosus in persistent clinical remission: experience from a multicentric cohort Alice Bartoletti¹, Laura Giudice¹, Lorenza Maria Argolini^1|2, Giuseppe Alvise Ramirez³, Luca Moroni³, Tommaso Schioppo⁴, Chiara Bellocchi^5|6, Annalaura Fasiello⁶, Lorenzo Beretta⁶, Lorenzo Dagna³, Roberto Caporali¹, Maria Gerosa¹. | ¹UO Clinica Reumatologica, ASST Gaetano Pini CTO, Milano, Italy; ²UOC Medicina fisica e riabilitazione specialistica, ASST Gaetano Pini CTO, Milano, Italy; ³Unit of Immunology, Rheumatology, Allergy and Rare Diseases, IRCCS San Raffaele Hospital, Vita-Salute San Raffa Milano Italy; ⁴Medicina Generale II, Servizio di Reumatologia, Ospedale San Paolo, ASST Santi Paolo Carlo, Milano, Italy; ⁵Department of Clinical Sciences and Community Health, University of Milan, Dipartimeto di Eccellenza 2023-2027, Milano, Italy; ⁶Referral Centre for Systemic Autoimmune DIseases, Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico, Milano, Italy

  Società Italiana di Reumatologia

  https://doi.org/10.4081/reumatismo.2025.2044

  165

• PO:16:233 | Efficacy of voclosporin on nephritis in patients with variable gain of function of TLR7 affected by lupus: clinical case Veronica Spedicato¹, Laura Coladonato¹, Marco Fornaro¹, Marlea Lavista¹, Daniele Sabella¹, Marco Capodiferro¹, Maria Morrone¹, Crescenzio Scioscia¹, Giuseppe Lopalco¹, Florenzo Iannone¹ | ¹Unit of Rheumathology, Department of Precision and Regenerative Medicina, Area Jonica^J, University of Bari, Italy

  Società Italiana di Reumatologia

  https://doi.org/10.4081/reumatismo.2025.2161

  147

• PO:16:234 | Differential efficacy of induction treatments for lupus nephritis at onset and relapses: an observational study Giuseppe Alvise Ramirez^1|2, Gabriele D Gallina¹, Chiara Calabrese^1|2, Serena Nannipieri^1|2, Marta Calatroni^3|4, Francesco Reggiani^3|4, Giovanni Benanti¹, Enrica Paola Bozzolo¹, Raffaele Ceniccola², Luca Moroni^1|2, Marco Matucci-Cerinic^1|2, Gabriella Moroni^3|4, Lorenzo Dagna^1|2 | ¹IRCCS San Raffaele Hospital, Unit of Immunology, Rheumatology, Allergy and Rare Diseases Milan, Italy; ²Vita- Salute San Raffaele University Milan, Italy; ³IRCCS Humanitas Research Hospital, Nephrology and Dialysis Division Rozzano, Milan, Italy; ⁴Humanitas University, Department of Biomedical Sciences Rozzano, Milan, Italy

  Società Italiana di Reumatologia

  https://doi.org/10.4081/reumatismo.2025.2334

  35

• PO:16:235 | Anifrolumab in systemic lupus erythematosus: real-life experience of a single-center cohort Filippo Vesentini¹, Luca Iaccarino¹, Federico Arru², Greta Hulej¹, Anna Giorgia Osele¹, Noemi Merra¹, Davide Ragno¹, Andrea Doria¹, Margherita Zen¹ | ¹UOC Reumatologia, Dipartimento di Medicina DIMED, Università degli Studi di Padova; ²UO Medicina, ASL 3 Nuoro, Italy

  Società Italiana di Reumatologia

  https://doi.org/10.4081/reumatismo.2025.2162

  129

• PO:16:236 | Achieving a low disease activity state with a corticosteroid dose of 5 mg or less: observational study with anifrolumab in patients with systemic lupus erythematosus in Italy Alessandra Bortoluzzi¹, Fulvia Ceccarelli², Fabio Leo³, Paola Roccatagliata³, Chiara Tani⁴, Margherita Zen⁵ | ¹Azienda Ospedaliera Universitaria Sant' Anna di Cona, Università di Ferrara Italy; ²Unità di Reumatologia, Università Sapienza Roma Italy; ³AstraZeneca S.p.a. Milano Italy; ⁴Università di Pisa e Azienda Ospedaliero Universitaria Pisana, Pisa Italy; ⁵Dipartimento di Medicina DIMED , Divisione di Reumatologia, Università di Padova, Italy

  Società Italiana di Reumatologia

  https://doi.org/10.4081/reumatismo.2025.2163

  119

• PO:16:238 | Cardiovascular risk in systemic lupus erythematosus patients: comparison among Framingham Score, QRISK3, and SLECRE Francesca Vignoni^1|2, Serena Iodice², Cesare Tomasi², Chiara Orlandi^1|2, Eleonora Pedretti¹, Micaela Fredi², Franco Franceschini^1|2, Ilaria Cavazzana^1|2. | ¹Rheumatology and Clinical Immunology Unit - ERN ReCONNET, ASST Spedali Civili of Brescia, Brescia, Italy; ²Department of Clinical and Experimental Sciences, University of Brescia, Brescia, Italy.

  Società Italiana di Reumatologia

  https://doi.org/10.4081/reumatismo.2025.2045

  130

• PO:16:240 | Systemic Lupus Erythematosus Presenting as End-Stage Liver Disease: A Case Report and Literature Review Annamaria Tiso¹, Stefania Caccavelli¹, Giuseppina Caroppi¹, Candida Tarullo¹, Gaetano Serviddio¹ | ¹Policlinico Riuniti Foggia, Italy

  Società Italiana di Reumatologia

  https://doi.org/10.4081/reumatismo.2025.2335

  44

• PO:16:241 | Prevalence and associated factors of premature ovarian insufficiency in women with systemic lupus erythematosus: the role of human herpesviruses HHV-7 and HHV-8 Margherita Rizzo¹, Francesca Ruffilli¹, Silvia Beltrami², Daria Bortolotti², Roberta Rizzo², Carlo Garaffoni¹, Ettore Silvagni¹, Marcello Govoni¹, Alessandra Bortoluzzi¹ | ¹UOC Reumatologia, Dipartimento di Scienze Mediche, Università di Ferrara e Azienda Ospedaliero-Universitaria S. Anna, Ferrara; ²Dipartimento di Scienze Chimiche, Farmaceutiche e Agrarie, Ferrara Italy

  Società Italiana di Reumatologia

  https://doi.org/10.4081/reumatismo.2025.2164

  150

• PO:17:248 | Prevention of human papillomavirus infection in women with systemic lupus erythematosus: a single-center cross-sectional study Clizia Gagliardi¹, Maria Chiara Gerardi¹, Bianca Lucia Palermo¹, Giulia Carrea¹, Maria Di Cicco¹, Elena Manna¹, Giulia Segatto¹, Antonella Adinolfi¹, Laura Belloli¹, Cinzia Casu¹, Silvia Cavalli¹, Davide Antonio Filippini¹, Matteo Longhi¹, Gabriella Maioli¹, Martina Schettino¹, Nicola Ughi¹, Elisa Verduci¹, Arianna Bertolucci¹, Lara Buffa¹, Giulia Buonsante¹, Claudia Cordini¹, Eleonora Giacobbe¹, Francesco Molica Colella¹, Oscar Epis¹ | ¹ASST Grande Ospedale Metropolitano Niguarda, Milano, Italy

  Società Italiana di Reumatologia

  https://doi.org/10.4081/reumatismo.2025.2165

  150

• PO:17:250 | Effectiveness and safety of the recombinant zoster vaccine in patients ≥18 years of age with systemic lupus Giulia Boschi¹, Sheryl A. Kluberg², Sophie E. Mayer², O'Mareen Spence³, Driss Oraichi³, Harry Seifert³, Omar Ali³, Huifeng Yun³, Andrew L. Simon⁴, Jenice S. Ko⁴, Caroline Hugh⁴, Meg Her⁴, Kathleen Shattuck⁴, Richard Platt², Aziza Jamal-Allial⁵, Djeneba Audrey Djibo⁶, Kimberly Daniels⁵, Qianli Ma⁷, Cheryl N. Mcmahill-Walraven⁶, Rachel P. Ogilvie⁸, Kristin Palmsten⁹, Mano Selvan⁷, Najat Ziyadeh⁸, Alexis Ogdie¹⁰, Michael George¹⁰ | ¹GSK Verona Italy; ²Harvard Medical School and the Department of Population Medicine, Harvard Pilgrim Health Care Institute, Boston; ³GSK Rockville; ⁴Department of Population Medicine, Harvard Pilgrim Health Care Institute, Boston; ⁵Carelon Research, Wilmington; ⁶CVS Health, Blue Bell; ⁷Humana Healthcare Research, Louisville; ⁸OptumInsight Life Sciences, Boston; ⁹HealthPartners Institute, Bloomington; ¹⁰University of Pennsylvania, Philadelphia, USA

  Società Italiana di Reumatologia

  https://doi.org/10.4081/reumatismo.2025.2166

  136

• PO:17:252 | The choice between belimumab and anifrolumab: analysis of a monocentric cohort Fabio Congiu¹, Elisabetta Chessa², Giulia Rizzo¹, Elena Ragusa¹, Marta Paola Pireddu¹, Alessandra Oliva¹, Marianna Salis¹, Mattia Congia², Maria Maddalena Angioni¹, Micaela Rita Naitza¹, Alberto Floris², Alberto Cauli^1|2, Matteo Piga^1|2 | ¹AOU e Università degli studi di Cagliari; ²SC Reumatologia PO Duilio Casula, Cagliari, Italy

  Società Italiana di Reumatologia

  https://doi.org/10.4081/reumatismo.2025.2167

  151

• PO:17:253 | Unveiling the gap: a multicenter study on factors driving patient-physician discrepancies in assessing disease activity in systemic lupus erythematosus Giorgia Ingrid Gozzoli¹, Micaela Fredi¹, Federica Bonaso¹, Silvia Ebe Lucia Della Pina¹, Claudia Barison¹, Irene Lorenzini⁴, Raffaele Pericotti⁴, Anna Mattiuzzo⁴, Marcelo Neto², Sofia Azevedo³, Cláudia Oliveira³, Cesare Tomasi⁴, Luís Sousa Inês², Franco Franceschini¹. | ¹Rheumatology and Clinical Immunology Unit, ASST Spedali Civili of Brescia, Brescia, Italy; ²Rheumatology Department, Centro Hospitalar Universitário de Coimbra - ULS Coimbra, Coimbra, Portugal; ³Rheumatology  Department, ULS Aveiro, Aveiro, Portugal; ⁴Department of Clinical and Experimental Sciences, University of Brescia, Brescia, Italy.

  Società Italiana di Reumatologia

  https://doi.org/10.4081/reumatismo.2025.2046

  144

• PO:17:254 | Systemic lupus erythematosus with pulmonary involvement: clinical insights from an Albanian cohort Arbi Pecani¹, Arian Mezini², Loreta Karaulli², Laert Gjati², Silvana Bala² | ¹Reumatologia, Dipartimento di Medicina Interna, Università di Medicina di Tirana, Ospedale Universitario Shefqet Ndroqi, Tirana; ²Pneumologia, Dipartimento di Medicina Respiratoria, Ospedale Universitario Shefqet Ndroqi, Tirana, Albania

  Società Italiana di Reumatologia

  https://doi.org/10.4081/reumatismo.2025.2168

  157

• PO:17:255 | Efficacy and safety of voclosporin in the management of lupus nephritis: a case series Alessandra Oliva¹, Elisabetta Chessa², Marta Paola Pireddu¹, Marianna Salis¹, Giulia Rizzo¹, Fabio Congiu¹, Elena Ragusa¹, Antonello Pani^3|4, Alberto Cauli^1|2, Nicola Lepori^3|4, Matteo Piga^1|2 | ¹UOC Reumatologia, Dipartimento di Scienze Mediche e Salute Pubblica, Università degli Studi di Cagliari; ²UOC Reumatologia, AOU Cagliari; ³SC Nefrologia e Dialisi, Università degli Studi di Cagliari; ⁴SC Nefrologia e Dialisi, Azienda Ospedaliera Brotzu, Cagliari, Italy

  Società Italiana di Reumatologia

  https://doi.org/10.4081/reumatismo.2025.2169

  149

• PO:17:259 | Anifrolumab: a new management of SLE Giorgia Montozzi¹, Chiara Cocco¹, Ramona Santangeli¹, Lucia Gamba¹, Paola Fioretti¹, Letizia Curina¹, Chiara Guidoni¹, Edoardo Cipolletta³, Gianluca Moroncini² | ¹Scuola di Specializzazione in Medicina Interna, Università Politecnica delle Marche Ancona, Italy; ²Department of Clinical and Molecular Sciences, Università Politecnica delle Marche Ancona, Italy; ³Rheumatology Unit, Department of Clinical and Molecular Sciences , Università Politecnica delle Marche Ancona, Italy

  Società Italiana di Reumatologia

  https://doi.org/10.4081/reumatismo.2025.2336

  45

• PO:18:264 | Anifrolumab in Systemic Lupus Erythematosus: Bridging Clinical Trial Data with Real-World Evidence Giulia Cassone², Filippo Santoro¹, Caterina Vacchi², Dilia Giuggioli², Chiara Cabassi¹ | ¹UOC Reumatologia, AOU Policlinico di Modena, Università degli studi di Modena e Reggio Emilia Modena e Reggio Emilia, Italy; ²UOC Reumatologia, AOU Policlinico di Modena Modena, Italy

  Società Italiana di Reumatologia

  https://doi.org/10.4081/reumatismo.2025.2337

  70

• PO:18:268 | Voclosporin as a Steroid-Sparing Agent in Lupus Nephritis Complicated by Central Serous Chorioretinopathy: A Case Report Irene Genovali^1|2, Sebastiano Lorusso², Damiano Currado^1|2, Letizia Pia Di Corcia¹, Ludovica Lamberti¹, Annalisa Marino², Antonio Orlando¹, Maria Quadrini¹, Marta Vadacca², Marta Vomero¹, Luca Navarini^1|2, Roberto Giacomelli^1|2 | ¹Rheumatology and Clinical Immunology, Department of Medicine, University of Rome Campus Biomedico, School of Medicine Rome, Italy; ²Clinical and Research Section of Rheumatology and Clinical Immunology Fondazione Policlinico Campus Biomedico Rome, Italy

  Società Italiana di Reumatologia

  https://doi.org/10.4081/reumatismo.2025.2338

  42

• PO:18:271 | Managing concomitant sle and psoriasis: the role of anifrolumab in a clinical case Angela Carenza¹, Liliana Dinoia², Sergio De Gioia², Federica Gatti¹, Teresa Caferri¹, Lucia Cristiana Colaprico¹, Angelica Napoletano¹, Giuseppe Lopalco¹, Florenzo Iannone¹. | ¹Rheumatology Unit, University of Bari, Department of Precision and Regenerative Medicine, Jonian area ^DiMePRe-J, Bari, Italy; ²Azienda Sanitaria Locale di Taranto, presidio ospedaliero SS. Annunziata, Unità Operativa di Reumatologia, Taranto, Italy.

  Società Italiana di Reumatologia

  https://doi.org/10.4081/reumatismo.2025.2047

  158

• PO:18:276 | Use of anifrolumab in the treatment of difficult-to-treat manifestations in systemic lupus erythematosus Antonella Grimaldi¹, Giuseppe Alessandrini², Laura Quarta¹, Maria Rita Ricciardi¹, Daniela Costanza¹, Clara Minerba¹, Eugenio Quarta¹ | ¹UOC Reumatologia Verona; ²Specialista Dermatologo in Libera Professione, Italy

  Società Italiana di Reumatologia

  https://doi.org/10.4081/reumatismo.2025.2170

  160

• PO:18:277 | Clinical case report of the management of a patient suffering from systemic lupus erythematosus and associated polyneuropathy Davide Murgia¹, Elena Marazzi¹, Rosetta Vitetta¹, Guido Rovera¹. | ¹ASLVC SSD reumatologia, Ospedale sant'Andrea Vercelli, Vercelli, Italy.

  Società Italiana di Reumatologia

  https://doi.org/10.4081/reumatismo.2025.2048

  144

• PO:19:279 | Predictors of proteinuria, amyloidosis and kidney failure in familial Mediterranean fever: data from the International AIDA Network Registry Jessica Sbalchiero¹, Antonio Vitale¹, Valeria Caggiano¹, Abdurrahman Tufan², Ezgi Batu³, Gaafar Ragab⁴, Seza Ozen³, Jurgen Sota¹, Carla Gaggiano¹, Ali Sahin⁵, Petros Sfikakis⁶, Francesca Li Gobbi⁷, Giacomo Emmi⁸, Jose Rodriguez⁹, Piero Ruscitti¹⁰, Paolo Sfriso¹¹, Ewa Szewczyk¹², Giuseppe Lopalco¹³, Alberto Balistreri¹⁴, Claudia Fabiani¹⁵, Bruno Frediani¹, Luca Cantarini¹ | ¹Department of Medical Sciences, Surgery and Neurosciences, University of Siena, Siena, Italy; ²Department of Internal Medicine, Division of Rheumatology, Gazi University Hospital Ankara, Turkey; ³Division of Pediatric Rheumatology, Department of Pediatrics, Hacettepe University School of Medicine Ankara, Turkey; ⁴Internal Medicine Department, Rheumatology and Clinical Immunology Unit, Faculty of Medicine, Cairo University Giza, Egypt; ⁵Division of Rheumatology, Department of Internal Medicine, Sivas Cumhuriyet University Medical Faculty Sivas, Turkey; ⁶Joint Academic Rheumatology Program, Medical School, National and Kapodistrian University of Athens Athens, Greece; ⁷Rheumatology Unit, Hospital S. Giovanni di Dio, Azienda USL-Toscana Centro Florence, Italy; ⁸Clinical Medicine and Rheumatology Unit, Cattinara University Hospital Trieste, Italy; ⁹Department of Autoimmune Diseases, Institut Investigacions Biomediques August Pi I Sunyer, University of Barcelona Barcelona Spain; ¹⁰Rheumatology Unit, Department of Biotechnological and Applied Clinical Sciences, University of L'Aquila, L'Aquila, Italy; ¹¹Rheumatology Unit, Department of Medicine, University of Padua Padua, Italy; ¹²7Department of Internal Medicine, Pneumonology, Allergology, Clinical Immunology and Rare Diseases, Military Institute o Warsaw, Poland; ¹³Department of Precision and Regenerative Medicine and Ionian Area DiMePRe-J Policlinic Hospital, University of Bari Bari, Italy; ¹⁴Bioengineering and Biomedical Data Science Lab, Department of Medical Biotechnologies, University of Siena Siena, Italy; ¹⁵Ophthalmology Unit, Department of Medicine, Surgery and Neurosciences, University of Siena Siena, Italy

  Società Italiana di Reumatologia

  https://doi.org/10.4081/reumatismo.2025.2339

  36

• PO:19:281 | Mitochondrial dysfunction in Still’s disease: a preliminary analysis of mtDNA copy number and TFAM expression Ludovica Manisera¹, Francesca Giansanti², Andrea Latini³, Francesca Lotito⁴, Serena Colafrancesco⁵, Angelica Gattamelata⁶, Fabrizio Conti⁷, Cinzia Ciccacci⁸, Roberta Priori⁹ | ^1|6|7|9La Sapienza, Roma; ^2|3|4|8Unicamillus, Roma; ⁵Humanitas, Milano, Italy

  Società Italiana di Reumatologia

  https://doi.org/10.4081/reumatismo.2025.2171

  151

• PO:19:283 | Hospitalization profile and complications in patients with adult-onset Still’s disease: results from a retrospective study of 74 cases Chiara Calabrese¹, Alessandro Tomelleri^1|2, Corrado Campochiaro^1|2, Nicola Farina², Elena Baldissera², Marco Matucci-Cerinic^1|2, Lorenzo Dagna^1|2 | ¹Libera Università Vita-Salute San Raffaele, Milano; ²Unità di Immunologia, Allergologia e malattie rare, IRCCS San Raffaele, Milano, Italy

  Società Italiana di Reumatologia

  https://doi.org/10.4081/reumatismo.2025.2172

  134

• PO:19:284 | Use of anakinra during pregnancy and breastfeeding in women with recurrent pericarditis: a case series Lucia Trotta¹, Marco Quartarone¹, Francesco Cavaleri¹, Ruggiero Mascolo¹, Massimo Imazio³, Vartan Mardygan², Andreja Cerne Cercek⁴, Anne-Marie Claveau², Ludovico Luca Sicignano⁵, Massimo Pancrazi¹, Alida Caforio⁶, Andrea Silvio Giordani⁶, Serdal Ugurlu⁷, Alessandro Andreis⁸, Valentino Collini³, Enrico Tombetti⁹, Antonio Brucato⁹ | ¹Department of Internal Medicine, ASST Fatebenefratelli-Sacco, Milan, Italy; ²Division of Cardiology, Department of Medicine, Jewish General Hospital, Montréal, Québec, Canada; ³Cardiology, Cardiothoracic Department, University Hospital Santa Maria della Misericordia, Udine, Italy; ⁴Department of Cardiology, University Medical Centre Ljubljana, Ljubljana, Slovenia; ⁵Fondazione Policlinico Universitario Agostino Gemelli IRCCS, Rome, Italy; ⁶Division of Cardiology, Centro Gallucci, University of Padova-Policlinico, Padova, Italy; ⁷Division of Rheumatology, Department of Internal Medicine, Istanbul University-Cerrahpasa, Istanbul, Turkey; ⁸University Cardiology, A.O.U. Città della Salute e della Scienza di Torino, Torino, Italy; ⁹Department of Biomedical and Clinical Sciences, Fatebenefratelli Hospital, University of Milan, Milan, Italy

  Società Italiana di Reumatologia

  https://doi.org/10.4081/reumatismo.2025.2340

  38

• PO:19:286 | Genetic testing reveals an unexpected case of mevalonate kinase deficiency in a 37-year-old patient with AA renal amyloidosis and good response to colchicine Francesca Crisafulli¹, Paolo Airò², Federica Mescia³, Gianmarco Lugli³, Gianfranco Savoldi⁴, Claudia Izzi^3|5, Federico Alberici³, Marco Cattalini⁶, Franco Franceschini¹, Micol Frassi². | ¹Rheumatology and Clinical Immunology Unit, ASST Spedali Civili and University of Brescia, Brescia, Italy; ²Rheumatology and Clinical Immunology Unit, ASST Spedali Civili of Brescia, Brescia, Italy; ³U.O Nefrologia, ASST Spedali Civili di Brescia e Università degli Studi di Brescia, Brescia, Italy; ⁴Medical genetics Laboratory, Laboratory Department ASST Spedali Civili di Brescia, Brescia, Italy; ⁵Struttura Complessa di Genetica Clinica, ASST Spedali Civili di Brescia, Brescia, Italy; ⁶Pediatrics Clinic, University of Brescia and ASST Spedali Civili of Brescia, Brescia, Italy.

  Società Italiana di Reumatologia

  https://doi.org/10.4081/reumatismo.2025.2049

  148

• PO:19:287 | Cardiac involvement in Still’s disease: a challenge in differential diagnosis Ludovica Manisera¹, Martina Dodaro², Giuseppe Norcia³, Angelica Gattamelata⁴, Nicola Galea⁵, Concetta Torromeo⁶, Gaetano Tanzilli⁷, Fabrizio Conti⁸, Roberta Priori⁹ | ¹Dipartimento di Scienze Cliniche, Internistiche, Anestesiologiche e Cardiovascolari, Università degli Studi di Roma La Sapienza, Roma; ²Dipartimento di Medicina Traslazionale e di Precisione, Università degli Studi di Roma La Sapienza, Roma; ³Dipartimento di Medicina Molecolare, Università degli Studi di Roma La Sapienza, Roma, Italy

  Società Italiana di Reumatologia

  https://doi.org/10.4081/reumatismo.2025.2173

  152

• PO:20:002 | Respiratory function tests predict bone mineral density in autoimmune rheumatic disease patients Andrea Zoli¹, Panagiotis Garantziotis², Sebastian Böltz², Janina Auth², Sara Bayat², Jule Taubmann², Anna-Maria Liphardt², Maria Antonietta D'Agostino¹, Christina Bergmann², Georg Schett². | ¹Division of Rheumatology, Fondazione Policlinico Universitario A. Gemelli, IRCCS, Università Cattolica del Sacro Cuore, Roma, Italy; ²Department of Medicine 3, Rheumatology and Immunology, Friedrich Alexander Universität FAU, Erlangen, Germany.

  Società Italiana di Reumatologia

  https://doi.org/10.4081/reumatismo.2025.2050

  143

• PO:20:003 | Romosozumab effect on neutrophil-to-lymphocyte ratio in post-menopausal women at high risk of fracture Giorgia Scagliosi¹, Mariana Diaz Lopez¹, Martina Teoni¹, Francesco Pollastri¹, Anna Piccinelli¹, Camilla Benini¹, Valeria Messina¹, Emma Pasetto¹, Davide Gatti¹, Ombretta Viapiana¹, Maurizio Rossini¹, Giovanni Adami¹. | ¹Università di Verona, Dipartimento di Medicina, Verona, Italy; ²Università di Verona, Dipartimento di Medicina, Verona, Italy; ³Università di Verona, Dipartimento di Medicina, Verona, Italy; ⁴Università di Verona, Dipartimento di Medicina, Verona, Italy; ⁵Università di Verona, Dipartimento di Medicina, Verona, Italy; ⁶Università di Verona, Dipartimento di Medicina, Verona, Italy; ⁷Università di Verona, Dipartimento di Medicina, Verona, Italy; ⁸Università di Verona, Dipartimento di Medicina, Verona, Italy; ⁹Università di Verona, Dipartimento di Medicina, Verona, Italy; ¹⁰Università di Verona, Dipartimento di Medicina, Verona, Italy; ¹¹Università di Verona, Dipartimento di Medicina, Verona, Italy; ¹²Università di Verona, Dipartimento di Medicina, Verona, Italy.

  Società Italiana di Reumatologia

  https://doi.org/10.4081/reumatismo.2025.2051

  141

• PO:20:004 | Increase in serum Dkk1 levels attenuates the anabolic response to romosozumab in postmenopausal osteoporosis Giovanni Adami¹, Filippo Montanari¹, Angelo Fassio¹, Francesco Pollastri¹, Anna Piccinelli¹, Davide Gatti¹, Ombretta Viapiana¹, Maurizio Rossini¹. | ¹Università degli Studi di Verona, Verona, Italy.

  Società Italiana di Reumatologia

  https://doi.org/10.4081/reumatismo.2025.2052

  126

• PO:20:005 | Sarcopenia and fracture risk in rheumatoid arthritis: correlation between SACR-F and fragility score measured by radiofrequency echographic multi-spectrometry Sara Torracchi¹, Pamela Bernardini¹, Daniela Melchiorre¹, Bianca Bossi¹, Dorilda Zeka¹, Francesca Nacci¹, Lorenzo Tofani¹, Serena Guiducci¹ | ¹SOD Reumatologia, Dipartimento di Medicina Sperimentale e Clinica, Università degli Studi di Firenze, Italy

  Società Italiana di Reumatologia

  https://doi.org/10.4081/reumatismo.2025.2174

  155

• PO:20:006 | Efficacy of denosumab in glucocorticoid-induced osteoporosis patients with prior exposure to intravenous aminobisphosphonates Kiren Khalid¹, Alessandro Giollo¹, Mariangela Salvato¹, Francesca Frizzera¹, Lorenzo Di Luozzo¹, Bernd Raffeiner², Andrea Doria¹ | ¹Rheumatology Unit, Department of Medicine - DIMED, University of Padova, Padova, Italy; ²Department of Rheumatology, Bolzano Central Hospital, Bolzano, Italy

  Società Italiana di Reumatologia

  https://doi.org/10.4081/reumatismo.2025.2341

  16

• PO:20:007 | Mind the rebound: ctx dynamics after denosumab discontinuation and zoledronate rescue in patients with postmenopausal osteoporosis or with cancer treatment-induced bone loss Federico Aldegheri¹, Francesca Ruzzon¹, Matteo Appoloni¹, Giovanni Adami¹, Davide Gatti¹, Maurizio Rossini¹, Angelo Fassio¹, Ombretta Viapiana¹ | ¹Università di Verona, Italy

  Società Italiana di Reumatologia

  https://doi.org/10.4081/reumatismo.2025.2342

  41

• PO:20:010 | Coordinated outpatient pathway for osteoporosis: a new organizational model for osteoporosis management Domenico Birra¹, Ornella Romano², Vincenza Sara Suppa², Mariavittoria Guerra¹, Carmine Fierarossa¹, Benedetta Tartaglia¹, Antonietta De Sena¹, Fabio Granato Corigliano¹, Serena Ippolito², Vincenzo Nuzzo¹ | ¹UOC Medicina Generale, P.O. Ospedale del Mare, Asl Napoli 1 Centro; ²U.O.S.D. Malattie Endocrine del ricambio e della nutrizione, P.O. Ospedale del Mare, Asl Napoli 1 Centro, Italy

  Società Italiana di Reumatologia

  https://doi.org/10.4081/reumatismo.2025.2175

  161

• PO:20:011 | Suspected tumor-induced osteomalacia in a patient with polymyalgia rheumatica and persistent hyperphosphaturic hypophosphatemia Andrea Faggiano^1|2, Francesco Goatelli^1|2, Lucia Dardani², Carlo Salvarani³ | ¹Unit of Rheumathology, Department of Precision and Regenerative Medicina, Area Jonica, University of Bari; ²Scuola di Specializzaione in Reumatologia, Università degli Studi di Modena e Reggio Emilia, Modena, Italy; ³Direttore SOC Reumatologia, IRCCS Arcispedale Santa Maria Nuova, AUSL REGGIO EMILIA, Italy  

  Società Italiana di Reumatologia

  https://doi.org/10.4081/reumatismo.2025.2176

  154

• PO:20:012 | Inflammatory markers and nutritional status in patients with osteoporotic fractures: preliminary analysis of a pilot study Domenico Birra¹, Manuela Maione², Carolina Bologna¹, Carmela Pierce², Paolo Tirelli¹, Gianluigi Cuomo¹, Carolina Sepe², Pasquale Madonna¹, Claudio De Luca¹, Federica Coretti², Vincenzo Nuzzo¹ | ¹S.C. Reumatologia, ASST Grande Ospedale Metropolitano Niguarda, Milano, Italy; ²U.O.S.D. Malattie Endocrine del ricambio e della nutrizione - P. O. Ospedale del Mare - Asl Napoli 1 centro, Napoli, Italy 

  Società Italiana di Reumatologia

  https://doi.org/10.4081/reumatismo.2025.2177

  122

• PO:20:014 | Post-partum osteoporosis: severe clinical presentation in absence of known risk factors Domenico Birra¹, Ludovica Frances Grasso², Vittoria Gammaldi¹, Antonietta De Sena¹, Carmine Pio Petrosino², Rosalia Boccia², Gabriella Oliva¹, Vincenzo Nuzzo¹ | ¹Dipartimento di Scienze Cliniche Internistiche, Anestesiologiche e Cardiovascolari, Sapienza Università di Roma; ²Istituto Superiore di Sanità, Roma

  Società Italiana di Reumatologia

  https://doi.org/10.4081/reumatismo.2025.2178

  163

• PO:21:018 | The role of rheumatologists in the diagnosis and monitoring of Whipple's disease Mariangela Salvato¹, Alessandro Giollo¹, Marco Cola², Francesca Frizzera¹, Kiren Khalid¹, Lorenzo Di Luozzo¹, Annamaria Cattelan², Andrea Doria¹ | ¹UOC Reumatologia, AOUI Padova, Italy; ²UOC Malattie infettive, AOUI Padova, Italy

  Società Italiana di Reumatologia

  https://doi.org/10.4081/reumatismo.2025.2343

  42

• PO:21:019 | Clinical phenotypes in IgG4-related disease: ACR/EULAR classification and practical limitations Mattia Caliste¹, Flavia D'Auria², Linda Mastromanno¹, Francesca Carfora², Carla Giordano³, Cristiano Alessandri¹, Marcella Visentini², Fabrizio Conti¹, Roberta Priori^1|4 | ¹Dipartimento Scienze Cliniche Internistiche, Anestesiologiche e Cardiovascolari, Sapienza Università di Roma; ²Dipartimento Medicina Traslazionale e di Precisione, Sapienza Università di Roma; ³Dipartimento Scienze Radiologiche, Oncologiche e Anatomo-patologiche, Sapienza Università di Roma; ⁴Saint Camillus International University of Health Science, UniCamillus, Roma, Italy

  Società Italiana di Reumatologia

  https://doi.org/10.4081/reumatismo.2025.2179

  123

• PO:21:021 | The eyes tell the story: a clinical case of Rosah syndrome Nicolò Sabbion¹, Sofia Vitale¹, Claudia Balicchia¹, Barbara Troise¹, Francesca Mascia¹, Eleonora Bassanello², Jacopo Croce², Federica Maiolini², Filippo Mazzi², Elisa Tinazzi², Francesca Bosello¹, Simonetta Friso¹, Lucia De Franceschi¹ | ¹Università degli Studi di Verona; ²Azienda Ospedaliera Universitaria Integrata, Verona, Italy

  Società Italiana di Reumatologia

  https://doi.org/10.4081/reumatismo.2025.2180

  252

• PO:21:026 | Identifying patient profiles to personalize care and improve quality of life in italian EGPA patients Francesca Torracca¹, Roberto Padoan², Giacomo Emmi^3|4, Lara Bernardi⁵, Maria Rosaria Mollo⁵, Omar Shalby⁵, Fabio Tedone⁶, Davide Cafiero⁶, Eugenia Durante¹ | ¹APACS APS ETS - Associazione Pazienti Sindrome di Churg Strauss EGPA Arosio, Italy; ²Rheumatology Unit, Department of Medicine DIMED, University of Padua, Italy; ³Department of Medical, Surgical and Health Sciences, University of Trieste, Italy; ⁴Clinical Medicine Rheumatology Unit, Cattinara University Hospital, Trieste, Italy; ⁵GlaxoSmithKline Medical Department Verona, Italy; ⁶Helaglobe SRL Firenze, Italy

  Società Italiana di Reumatologia

  https://doi.org/10.4081/reumatismo.2025.2344

  19

• PO:21:028 | A difficult case of VEXAS syndrome: management of myelodysplastic syndrome associated with systemic inflammation and infectious complications Sandra Lombardi¹, Monica Regis¹, Stefano De Luca¹, Monica Poiani², Rossella Stella², Elisa Lucchini², Francesco Zaja², Fabio Fiammengo¹ | ¹SC Medicina Interna, Azienda Sanitaria Universitaria Giuliano Isontina, Gorizia; ²SC Ematologia, Azienda Sanitaria Universitaria Giuliano Isontina, Trieste, Italy

  Società Italiana di Reumatologia

  https://doi.org/10.4081/reumatismo.2025.2181

  152

• PO:22:029 | Impact of mepolizumab on idiopathic hypereosinophilic syndromes: analysis of a monocentric retrospective cohort Jacopo Mora¹, Francesca Regola¹, Paola Toniati², Ilaria Cavazzana¹, Franco Franceschini¹. | ¹ASST Spedali Civili e Università degli Studi di Brescia, Brescia, Italy; ²ASST Spedali Civili di Brescia, Brescia, Italy.

  Società Italiana di Reumatologia

  https://doi.org/10.4081/reumatismo.2025.2053

  130

• PO:22:032 | Beyond the joints: a rare case of subcorneal pustular dermatosis in Rheumatoid Arthritis Sara Casella^1|2, Carlo Smirne^1|2, Roberta Zaira Pedrazzoli³, Mattia Perazzi^1|3, Edoardo Cammarata⁴, Francesca Zottarelli⁴, Paola Savoia⁵, Renzo Boldorini⁶, Mario Pirisi^1|2, Pier Paolo Sainaghi^1|3 | ¹Dipartimento di Medicina Traslazionale, Università del Piemonte Orientale Novara, Italy; ²Unità di Medicina Interna, Azienda Ospedaliera Maggiore della Carità Novara, Italy; ³Unità di Medicina Interna e Reumatologia, Azienda Ospedaliera Maggiore della Carità Novara, Italy; ⁴Unità di Dermatologia, Azienda Ospedaliera Maggiore della Carità Novara, Italy; ⁵Dipartimento di Scienze della salute, Università del Piemonte Orientale Novara, Italy; ⁶Unità di Anatomia Patologica, Azienda Ospedaliera Maggiore della Carità Novara, Italy

  Società Italiana di Reumatologia

  https://doi.org/10.4081/reumatismo.2025.2345

  37

• PO:22:033 | Unraveling VEXAS syndrome: when skin manifestations and monoclonal gammopathy precede hematological myeloid alterations Laura Di Centa¹, Simone Longhino¹, Valeria Manfrè¹, Stefania Sacco¹, Luca Quartuccio¹ | ¹ASST Papa Giovanni XXIII, Bergamo, Italy

  Società Italiana di Reumatologia

  https://doi.org/10.4081/reumatismo.2025.2182

  153

• PO:22:038 | Recurrent Pneumonias and Persistent Inflammation in VEXAS Syndrome: The Role of BAL in Differential Diagnosis Francesco Ghellere¹, Bernardo D'Onofrio¹, Maria Chiara Ditto¹, Salvatore Panaro¹, Francesca Piccione^1|2, Giacomo Tanti¹, Enrico Fusaro¹, Simone Parisi¹ | ¹SC Reumatologia, Città della Salute e della Scienza Torino, Italy; ²Fondazione Ricerca Molinette Torino, Italy

  Società Italiana di Reumatologia

  https://doi.org/10.4081/reumatismo.2025.2346

  19

• PO:22:039 | A rare form of interstitial lung disease: granulomatous and lymphocytic interstitial lung disease Francesca Cozzini^1|2, Francesco Falco¹, Alberto Cavazza¹, Lucia Spaggiari³, Chiara Marvisi¹, Francesca Petrillo^1|2, Caterina Ricordi^1|2, Francesco Muratore^1|2, Fabio Brandolino¹, Ilaria Chiapparoli¹, Carlo Salvarani^1|2, Andreina Manfredi^1|2 | ¹IRCCS Policlinico San Matteo, UO di Reumatologia, Pavia; ²Università degli studi di Modena e Reggio Emilia, Modena, Italy

  Società Italiana di Reumatologia

  https://doi.org/10.4081/reumatismo.2025.2183

  125

• PO:23:044 | Understanding fatigue through patients' eyes: development of a novel questionnaire capturing the complexity of real-life fatigue in Sjögren's disease Flavia Riccio¹, Mariachiara Visconti¹, Corrado Parlati¹, Nicola Della Rossa¹, Sabrina Marrone¹, Enrico Tirri², Francesco Ciccia¹, Saviana Gandolfo². | ¹UOC di Reumatologia, Università degli Studi della Campania Luigi Vanvitelli, Napoli, Italy; ²UO di Reumatologia, Ospedale del Mare, Napoli, Italy.

  Società Italiana di Reumatologia

  https://doi.org/10.4081/reumatismo.2025.2054

  144

• PO:23:046 | Histopathological comparison between minor salivary gland biopsies from pediatric and adult patients with Sjögren’s disease: evidence of a more severe inflammatory profile in early-onset cases Flavia Riccio¹, Mattia Neri², Martina Mellone¹, Immacolata Cozzolino³, Jacopo Ferro⁴, Valerio Gaetano Vellone⁴, Ciro Emiliano Boschetti⁵, Giuseppe Colella⁵, Nicola Laffi⁶, Pietro Buono⁷, Enrico Tirri⁸, Renato Franco³, Marco Gattorno², Francesco Ciccia¹, Clara Malattia², Saviana Gandolfo⁸ | ¹UOC di Reumatologia, Università degli Studi della Campania Luigi Vanvitelli, Napoli; ²UOC di Reumatologia e Malattie Autoinfiammatorie, Istituto Giannina Gaslini, Genova; ³UO di Anatomia Patologica, Università degli Studi della Campania Luigi Vanvitelli, Napoli; ⁴UOC di Anatomia Patologica, Istituto Giannina Gaslini Genova; ⁵UOC di Chirurgia Maxillo-facciale, Università degli Studi della Campania Luigi Vanvitelli, Napoli; ⁶UO di Odontoiatria, Istituto Giannina Gaslini, Genova; ⁷UOD Attività consultoriali e assistenza materno-infantile, Direttorato Generale per la Salute, Regione Campania, Napoli; ⁸UO di Reumatologia, Ospedale del Mare, Napoli, Italy

  Società Italiana di Reumatologia

  https://doi.org/10.4081/reumatismo.2025.2184

  164

• PO:23:048 | Clinical and serological differences of an Italian Sjögren’s disease cohort according to three geographic macro-area localization Maria Letizia Currò¹, Roberto Dal Pozzolo², Giacomo Cafaro², Valeria Manfrè³, Gaetano La Rocca⁴, Alessia Alunno⁵, Francesco Carubbi⁵, Nicoletta Del Papa⁶, Viktoriya Pavlych⁷, Angelica Gattamelata⁸, Letizia Pia Di Corcia⁹, Pamela Bernardini¹⁰, Luca Quartuccio³, Chiara Baldini⁴, Paola Cipriani⁷, Roberta Priori⁸, Onorina Berardicurti⁹, Serena Guiducci¹⁰, Fabiola Atzeni¹, Elena Bartoloni² | ¹Unità di Reumatologia. Università di Messina, Italy; ²SC Reumatologia. Università di Perugia, Italy; ³Unità di Reumatologia. Università di Udine, Italy; ⁴Unità di Reumatologia. Università di Pisa, Italy; ⁵Divisione di Medicina Interna e Nefrologia. Università di L'Aquila, Italy; ⁶Dipartimento di Reumatologia. Università di Milano, Italy; ⁷Unità di Reumatologia. Università di L'Aquila, Italy; ⁸UOC Reumatologia. Università Sapienza Roma, Italy; ⁹Unità di Reumatologia. Università Campus Biomedico Roma, Italy; ¹⁰Unità di Reumatologia. Università di Firenze, Italy

  Società Italiana di Reumatologia

  https://doi.org/10.4081/reumatismo.2025.2347

  20

• PO:23:051 | Quantitative high-resolution computed tomography analysis in Sjögren’s disease-associated interstitial lung disease: CALIPER-derived imaging biomarkers for prognostic assessment Gaetano La Rocca¹, Francesco Ferro¹, Vincenzo Uggenti², Beatrice Dei¹, Giovanni Fulvio¹, Michele Moretti¹, Chiara Romei², Marta Mosca¹, Chiara Baldini¹. | ¹University of Pisa, Rheumatology Unit, Clinical and Experimental Medicine Department, Pisa, Italy; ²Department of Diagnostic Imaging, Pisa University Hospital, Pisa, Italy.

  Società Italiana di Reumatologia

  https://doi.org/10.4081/reumatismo.2025.2055

  159

• PO:23:052 | Muscular and myocardial involvement in antisynthetase syndrome: a retrospective real-life study Giulia Buonsante^1|2|3, Giacomo De Luca^1|2|3, Veronica Batani^1|2, Daniele Scaramuzzi^1|2|3, Lorenzo Dagna^1|2|3, Marco Matucci-Cerinic^1|2|3, Corrado Campochiaro^1|2|3. | ¹Unit of Immunology, Rheumatology, Allergy and Rare Diseases UNIRAR, IRCCS San Raffaele Hospital, Milano, Italy; ²Inflammation, Fibrosis and aging Initiative INFLAGE, IRCCS San Raffaele Hospital, Milano, Italy; ³Vita-Salute San Raffaele University, Milan, Italy, Milano, Italy.

  Società Italiana di Reumatologia

  https://doi.org/10.4081/reumatismo.2025.2056

  152

• PO:23:055 | Overlap of systemic sclerosis and Sjögren’s disease: insights from an Italian case-control study Stefano Stano¹, Fabio Cacciapaglia^1|2, Maria Morrone¹, Simone Perniola¹, Marco Capodiferro¹, Marco Fornaro¹, Laura Coladonato¹, Giuseppe Lopalco¹, Florenzo Iannone¹. | ¹Rheumatology Unit - Department of Precision and Regenerative Medicine, Jonian Area DiPReMeJ, University of Bari, Bari, Italy; ²Rheumatology Service, Internal Medicine Unit F. Miulli General Hospital, Department of Medicine and Surgery, LUM Casamassima Italy.

  Società Italiana di Reumatologia

  https://doi.org/10.4081/reumatismo.2025.2057

  210

• PO:24:056 | Major salivary gland ultrasonographic features of lymphoma and high lymphoproliferative risk lesions in Sjögren’s disease: a systematic review Alessia Nano¹, Valeria Manfrè¹, Maria Teresa Rizzo¹, Garifallia Sakellariou², Alen Zabotti¹, Luca Quartuccio¹. | ¹Division of Rheumatology, Department of Medicine DMED, ASUFC, University of Udine, Udine, Italy; ²Department of Internal Medicine and Therapeutics, University of Pavia, Pavia, Italy.

  Società Italiana di Reumatologia

  https://doi.org/10.4081/reumatismo.2025.2058

  136

• PO:24:057 | Qualitative and quantitative analysis of nailfold videocapillaroscopy in patients with idiopathic inflammatory myopathies: focus on muscle histology Jacopo Landro¹, Marius Cadar¹, Davide Mohammad Reza Beigi^1|2, Ilaria Bisconti¹, Francesca Romana Di Ciommo¹, Elena Platania¹, Martina Salerno¹, Beatrice De Girolamo¹, Annalisa Villa¹, Angelica Gattamelata¹, Simona Truglia¹, Cristiano Alessandri¹, Fabrizio Conti¹, Valeria Riccieri¹. | ¹Policlinico Umberto I, Roma, Italy; ²Clinica Reumatologica Madonna dello Scoglio, Cotronei, Italy.

  Società Italiana di Reumatologia

  https://doi.org/10.4081/reumatismo.2025.2059

  129

• PO:24:058 | Serum ferritin as a biomarker in idiopathic inflammatory myopathies with interstitial lung disease: baseline levels and longitudinal trends Silvia Grazzini¹, Edoardo Conticini¹, Marco Fornaro², Chiara Rizzo³, Federica Camarda³, Paolo Cameli⁴, Miriana D'Alessandro⁴, Lidia La Barbera³, Stefano Stano², Maria Rosa Pellico⁵, Latika Gupta⁶, Florenzo Iannone², Giuliana Guggino³, Elena Bargagli⁴, Nicoletta Del Papa⁵, Luca Cantarini¹, Bruno Frediani¹. | ¹Reumatologia, Dipartimento di Scienze Mediche, Chirugiche e Neuroscienze, Università di Siena, Siena, Italy; ²Reumatologia, Dipartimento di Emergenza e Trapianto d'Organo, Università di Bari, Bari, Italy; ³Reumatologia, Promozione della Salute, Materno-Infantile, di Medicina Interna e Specialistica, Università di Palermo, Palermo, Italy; ⁴Pneumologia, Dipartimento di Scienze Mediche, Chirugiche e Neuroscienze, Università di Siena, Siena, Italy; ⁵Reumatologia Clinica e Scienze Mediche, ASST Gaetano Pini CTO, Milano, Italy; ⁶University of Manchester, Manchester, United Kingdom.

  Società Italiana di Reumatologia

  https://doi.org/10.4081/reumatismo.2025.2060

  128

• PO:24:059 | Sjögren's disease-associated Fibromyalgia: pitfalls in disease assessment using ESSDAI and ESSPRI Lucia Cristiana Colaprico¹, Stefano Stano¹, Daniele Domanico¹, Maria Iacovantuono², Eduardo Urgesi³, Fabio Cacciapaglia^1|4, Maria Giannotta¹, Paola Conigliaro², Vincenzo Venerito¹, Maria Sole Chimenti², Giuseppe Lopalco¹, Florenzo Iannone¹ | ¹Rheumatology Unit - Department of Precision and Regenerative Medicine, Jonian Area DiPReMeJ, University of Bari, Bari, Italy; ²University of Rome Tor Vergata, Rheumatology, Allergology and Clinical Immunology, Department of Systems Medicine, Roma, Italy; ³University Cardiologic Unit - Interdisciplinary Department of Medicine - Policlinico University Hospital, University Bari, Italy; ⁴Rheumatology Service, Internal Medicine Unit F. Miulli General Hospital, Department of Medicine and Surgery, LUM Casamassima, Italy

  Società Italiana di Reumatologia

  https://doi.org/10.4081/reumatismo.2025.2348

  30

• PO:24:060 | Evaluation of a Large Language Model Performance in Rating Cutaneous Manifestations of Dermatomyositis: A Comparison with Expert Assessors Gianmarco Roselli¹, Marco Fornaro¹, Swapnasha Panigrahi², Sara Sabbagh³, Florenzo Iannone¹, Vincenzo Venerito¹, Latika Gupta⁴ | ¹Università degli Studi di Bari, Unità di Reumatologia, DiMePRe-J Bari, Italy; ²University of Birmingham Birmingham, United Kingdom; ³Medical College of Wisconsin, Unit of Rheumatology, Department of Paediatrics Milwaukee, USA; ⁴University of Manchester, Manchester Academic Health Centre, Division of muscoloskeletal and deramatological sciences Manchester, United Kingdom

  Società Italiana di Reumatologia

  https://doi.org/10.4081/reumatismo.2025.2349

  15

• PO:24:061 | Allodynia is highly prevalent in patients with Sjögren’s disease and correlates with immunobiological disease markers: preliminary results from the sjnapse project Flavia Riccio¹, Maria Chiara Visconti¹, Corrado Parlati¹, Nicola Della Rossa¹, Sabrina Marrone¹, Enrico Tirri², Francesco Ciccia¹, Saviana Gandolfo² | ¹UOC di Reumatologia, Università degli Studi della Campania Luigi Vanvitelli, Napoli; ²UO di Reumatologia, Ospedale del Mare, Napoli, Italy

  Società Italiana di Reumatologia

  https://doi.org/10.4081/reumatismo.2025.2185

  150

• PO:24:062 | Transcriptomic profile of salivary glands in patients with primary Sjögren’s syndrome and interstitial lung disease: implications for pathogenesis and risk stratification Elisa Pignatti¹, Monia Maccaferri¹, Alessandra Bisagni², Alberto Cavazza², Marco Sebastiani^3|4, Luca Keller², Luca Magnani⁵, Claudio Galluzzo², Tommaso Fasano⁶, Lucia Nota⁶, Giulia Canu⁶, Andreina Manfredi^1|2, Carlo Salvarani^1|2 | ¹Dipartimento Chimomo, Università di Modena e Reggio Emilia Modena; ²Struttura Complessa di Reumatologia, Azienda Unità Sanitaria Locale di Reggio Emilia-IRCCS; ³Dipartimento di Medicina e Chirurgia, Università degli Studi di Parma; ⁴Divisione di Reumatologia, AUSL di Piacenza; ⁵UOC Medicina Interna ind. reumatologico, AUSL di Bologna, Ospedale Maggiore, Bologna; ⁶Dipartimento Interaziendale ad Attività Integrata Medicina di Laboratorio ed Anatomia Patologica AUSL di Modena, Italy

  Società Italiana di Reumatologia

  https://doi.org/10.4081/reumatismo.2025.2186

  138

• PO:24:063 | Interstitial lung disease in idiopathic inflammatory myopathy patients: efficacy and safety of nintedanib Giulia Buonsante^1|2|3, Giacomo De Luca^1|2|3, Veronica Batani^1|2, Lorenzo Dagna^1|2|3, Marco Matucci-Cerinic^1|2|3, Corrado Campochiaro^1|2|3 | ¹Unit of Immunology, Rheumatology, Allergy and Rare Diseases UNIRAR, IRCCS San Raffaele Hospital Milano, Italy; ²Inflammation, Fibrosis and aging Initiative INFLAGE, IRCCS San Raffaele Hospital Milano, Italy; ³Vita-Salute San Raffaele University, Milano, Italy

  Società Italiana di Reumatologia

  https://doi.org/10.4081/reumatismo.2025.2350

  35

• PO:24:064 | IPF vs CTD-ILD: Survival and Lung Function from an Italian Real-World Cohort Marco Fornaro¹, Donato Lacedonia², Lorenzo Cavagna³, Paolo Airò⁴, Marco Sebastiani⁵, Gianluca Sambataro⁶, Fabio Cacciapaglia⁷, Angelica Napoletano¹, Cosimo De Pace², Pasquale Tondo², Giulia Scioscia², Eleonora Pedretti⁴, Maria Grazia Lazzaroni⁴, Carlo Vancheri⁸, Andreina Manfredi⁹, Lorenzo Binchessi³, Rocco Capece³, Michele De Ceglie¹⁰, Massimo Giotta¹¹, Florenzo Iannone¹ | ¹Unit of Rheumatology, Department of Precision and Regenerative Medicine - Area Jonica DiMePRe-J, University of Bari, Bari, Italy; ²Department of Medical and Surgical Sciences, University of Foggia Foggia, Italy; ³Department of Internal Medicine and Therapeutics, University of Pavia, Division of Rheumatology, Fondazione IRCCS, Pavia, Italy; ⁴Rheumatology and Clinical Immunology Unit, Department of Clinical and Experimental Sciences, ASST Spedali Civili Brescia, Italy; ⁵Rheumatology Unit, AUSL Piacenza, Department of Medicine and Surgery, University of Parma, Parma, Italy; ⁶Department of Medicine and Surgery, University of Enna Kore, Enna, Italy; ⁷Rheumatology Service, F. Miulli Hospital and Department of Medicine and Surgery, LUM University, Casamassima, Italy; ⁸Department of Clinical and Experimental Medicine, Regional Referral Center for Rare Lung Diseases, Catania, Italy; ⁹Rheumatology Unit, IRCCS Santa Maria Nuova Reggio Emilia, University of Modena, Modena, Italy; ¹⁰DIM, Interdisciplinary Department of Medicine, Section of Diagnostic Imaging, University of Bari, Bari, Italy; ¹¹Health Prevention Department, Local Health Authority of Brindisi, Brindisi, Italy

  Società Italiana di Reumatologia

  https://doi.org/10.4081/reumatismo.2025.2351

  27

• PO:24:065 | Nailfold capillaroscopic in primary Sjögren's syndrome, clinical and serological correlations; a preliminary report from a reference center Caterina Vacchi¹, Filippo Santoro¹, Maria Grazia Malandra¹, Giulia Cassone¹, Alessandra Carobbio², Martina Orlandi¹, Dilia Giuggioli¹ | ¹Reumatologia Modena, Italy; ²Statistica Medica Modena, Italy

  Società Italiana di Reumatologia

  https://doi.org/10.4081/reumatismo.2025.2352

  17

• PO:24:066 | Antibody profile in myositis and early risk of interstitial lung disease: clinical and laboratory correlations in patients with suspected rheumatologic disease Lindsay Brooke Boling¹, Gaia Deleonardi², Alarico Ariani³, Tania Silvestri², Ana Gabriela Grondona², Marica Trevisani³, Rita Mulè³, Enrica Vandelli³, Gentiana Vukatana³, Elisa Rossi³, Olga Addimanda³, Francesca Bergossi³, Angela Buffa³, Giovanni B. Canestrari³, Francesco Cianci³, Daniela Chiarini³, Laura Gigante³, Nicolò Girolimetto³, Daniele Lini³, Luca Magnani³, Mirco Magnani³, Erika Meleddu³, Francesca Pignataro³, Sofia Testoni³, Massimo Reta³ | ¹Scuola di Allergologia ed Immunologia Clinica-Università di Bologna; ²LUM Laboratorio Unico Metropolitano - Immunologia Clinica, Ospedale Maggiore, Bologna; ³UO Medicina Interna ad indirizzo reumatologico SC interaziendale - IRCCS AOU, AUSL Bologna, Italy

  Società Italiana di Reumatologia

  https://doi.org/10.4081/reumatismo.2025.2187

  162

• PO:24:068 | Case Report: ‘Spontaneous Pneumomediastinum in a Patient with MDA5-Positive Dermatomyositis and Severe Pulmonary Fibrosis’ Carlotta Braga¹, Margherita Rizzo¹, Marta Raschellà¹, Beatrice Maranini¹, Gioacchino Schifino², Aldo Carnevale³, Marcello Govoni¹, Andrea Lo Monaco¹ | ¹Rheumatology Unit, Department of Medical Sciences, University of Ferrara and Azienda Ospedaliero-Universitaria S. Anna Ferrara, Italy; ²Respiratory Medicine Unit, Department of Cardio-Thoracic-Vascular Pathologies, Arcispedale Sant'Anna, Ferrara, Italy; ³Radiology Unit, Department of Translational Medicine, University of Ferrara, Italy

  Società Italiana di Reumatologia

  https://doi.org/10.4081/reumatismo.2025.2353

  25

• PO:24:070 | Preliminary descriptive data from a single-centre cohort of patients with idiopathic inflammatory myopathy: focus on paraneoplastic and non-paraneoplastic patients Silvia Ebe Lucia Della Pina¹, Paola Bizioli¹, Samantha Mazza², Caproli Alessia¹, Cesare Tomasi¹, Ilaria Cavazzana¹, Franco Franceschini¹. | ¹S.C.O. Reumatologia ed Immunologia Clinica, ASST Spedali Civili di Brescia, Università degli Studi di Brescia, Brescia, Italy; ²Università degli Studi di Brescia, Brescia, Italy.

  Società Italiana di Reumatologia

  https://doi.org/10.4081/reumatismo.2025.2061

  133

• PO:25:071 | Gender differences in Sjögren’s disease: clinical activity, illness perception, and emotional impact Ilenia Fischetti¹, Martina Salerno¹, Linda Mastromanno¹, Angelica Gattamelata¹, Martina Villa¹, Ludovica Manisera¹, Emanuele Grilli¹, Luca Quartuccio², Valeria Manfrè², Francesco Carubbi³, Evy Di Ruscio³, Fabrizio Conti¹, Roberta Priori^1|4 | ¹UOC di Reumatologia, Dipartimento SCIAC, Sapienza Università di Roma; ²Dipartimento di Medicina, Clinica di Reumatologia, Università degli Studi di Udine; ³UOC Medicina Interna e Nefrologia, Dipartimento MeSVA, Università degli Studi di L'Aquila; ⁴UniCamillus, San Camillo Università Internazionale di Scienze della Salute di Roma, Italy

  Società Italiana di Reumatologia

  https://doi.org/10.4081/reumatismo.2025.2188

  135

• PO:25:073 | Pulmonary involvement and progressive interstitial lung disease in anti-synthetase syndrome: a single-center retrospective study Daniele Scaramuzzi^1|3, Giacomo De Luca^1|3, Veronica Batani¹, Giulia Buonsante^1|3, Lorenzo Dagna^1|3, Marco Matucci-Cerinic^1|2|3, Corrado Campochiaro^1|2|3 | ¹Unità di Immunologia, Reumatologia, Allergologia e Malattie Rare, IRCCS Ospedale San Raffaele, Milano; ²Inflammation, Fibrosis and Ageing Initiative INFLAGE, IRCCS San Raffaele Hospital, Milano; ³Università Vita-Salute San Raffaele, Milano, Italy

  Società Italiana di Reumatologia

  https://doi.org/10.4081/reumatismo.2025.2189

  138

• PO:25:074 | Capillaroscopic assessment in interstitial lung disease: a comparative study between connective tissue disease-associated interstitial lung disease, interstitial pneumonia with autoimmune features, and idiopathic pulmonary fibrosis Daniele Vito Andrea Sabella¹, Marco Fornaro¹, Laura Coladonato¹, Marlea Lavista¹, Veronica Spedicato¹, Giuseppe Lopalco¹, Florenzo Iannone¹. | ¹University of Bari, Rheumatology Unit Department of Precision and Regenerative Medicine - Jonica Area DiMePRe-J, Bari, Italy.

  Società Italiana di Reumatologia

  https://doi.org/10.4081/reumatismo.2025.2062

  128

• PO:25:075 | Cancer occurence in patients with idiopathic inflammatory myopathies: new insights from the analysis of a monocentric cohort Michele Diomedi¹, Federico Fattorini¹, Simone Barsotti², Chiara Cardelli^1|3, Elenia Laurino⁴, Alessandra Tripoli⁴, Linda Carli⁴, Marta Mosca^1|4. | ¹Rheumatology Unit, Department of Clinical and Experimental Medicine, University of Pisa, Pisa, Italy; ²Rheumatology, Versilia Hospital, Viareggio, Italy; ³Department of Medical Biotechnologies, University of Siena, Siena, Italy; ⁴Rheumatology Unit, AOUP, Pisa, Italy.

  Società Italiana di Reumatologia

  https://doi.org/10.4081/reumatismo.2025.2063

  138

• PO:25:079 | Anifrolumab in refractory dermatomyositis: a case report Chiara Calabrese¹, Corrado Campochiaro^1|2, Giacomo De Luca ^1|2, Veronica Batani¹, Marco Matucci-Cerinic^1|2, Lorenzo Dagna ^1|2 | ¹Dipartimento di Reumatologia e Scienze Mediche, ASST Centro Specialistico Ortopedico Traumatologico Gaetano Pini-CTO Milano; ²Università degli Studi di Milano, Dipartimento di Fisiopatologia Medico-Chirurgica e Trapianti, Milano, Italy

  Società Italiana di Reumatologia

  https://doi.org/10.4081/reumatismo.2025.2190

  147

• PO:25:081 | Atypical onset of anti-SAE-1 positive dermatomyositis: paraneoplastic flame hemorrhages in urothelial carcinoma Valentina Morandi¹, Alessandro Biglia², Francesco Maggiore¹, Sofia Chiricolo¹, Silvia Sammorì¹, Maria Cristina Sacchi^3|4, Edoardo Cammarata⁵, Maria Rosa Pellico⁶, Luigi Mario Castello^2|3|7. | ¹Dipartimento di Medicina Interna, SSD Reumatologia, AOUAL Santi Antonio e Biagio e Cesare Arrigo, Alessandria, Italy; ² Dipartimento di Medicina Interna, AOUAL Santi Antonio e Biagio e Cesare Arrigo, Alessandria, Italy; ³Dipartimento di laboratorio di tecnologia, ricerca e innovazione DAIRI, AOUAL Santi Antonio e Biagio e Cesare Arrigo, Alessandria, Italy; ⁴AOUAL Santi Antonio e Biagio e Cesare Arrigo, Laboratorio Analisi, Alessandria, Italy; ⁵AOUAL Santi Antonio e Biagio e Cesare Arrigo, Dipartimento di Medicina Interna, SSD Dermatologia, Alessandria, Italy; ⁶ASST Gaetano Pini, divisione di Reumatologia Clinica, Milano, Italy; ⁷Università del Piemonte orientale, dipartimento di Medicina Traslazione, Novara, Italy.

  Società Italiana di Reumatologia

  https://doi.org/10.4081/reumatismo.2025.2064

  160

• PO:25:082 | Progressive interstitial lung disease secondary to Sjögren's disease in a patient with inclusion body myositis complicated by dysphagia: a multidisciplinary approach and therapeutic challenges Emanule Cocchiara¹, Francesco Falco¹, Lucia Spaggiari³, Francesca Cozzini^1|2, Lucia Dardani¹, Gianluigi Bajocchi¹, Andreina Manfredi^1|2, Carlo Salvarani^1|2 | ¹Dipartimento di Medicina, Clinica Reumatologica, Udine; ²Università degli studi di Modena e Reggio Emilia, Modena; ³AUSL area NORD, Guastalla-Montecchio, Italy 

  Società Italiana di Reumatologia

  https://doi.org/10.4081/reumatismo.2025.2191

  143

• PO:25:083 | Overlap between Sjögren’s syndrome and lichen sclerosus: beyond coincidence? Emanuele Giovanni Grilli¹, Ludovica Manisera¹, Ilenia Fischetti¹, Linda Mastromanno¹, Martina Villa¹, Angelica Gattamelata¹, Fabrizio Conti¹, Roberta Priori^1|2, Serena Colafrancesco^3|4 | ¹Dipartimento di Medicina e Chirurgia, Università Milano-Bicocca; ²U.O. Reumatologia, IRCCS Fondazione San Gerardo dei Tintori, Monza; ³U.O. Pneumologia, IRCCS Fondazione San Gerardo dei Tintori, Monza; ⁴Rheumatology and Clinical Immunology, Istituto di Ricovero e Cura a Carattere Scientifico, IRCCS Humanitas Research Hosp, Rozzano, Milano, Italy 

  Società Italiana di Reumatologia

  https://doi.org/10.4081/reumatismo.2025.2192

  176

• PO:25:085 | Anti-MDA5 antibody syndrome, a life-threatening condition for rheumatologist and pulmonologist A case series Francesca Cozzini^1|2, Cecilia Burattini¹, Elena Bravi¹, Chiara Nani¹, Eugenio Arrigoni¹, Fabia Cavallotti¹, Ilaria Platè¹, Marco Sebastiani^1|3 | ¹Ospedale Guglielmo da Saliceto Piacenza, Italy; ²Università degli studi di Modena e Reggio Emilia, Italy; ³Università degli Studi di Parma, Italy

  Società Italiana di Reumatologia

  https://doi.org/10.4081/reumatismo.2025.2354

  40

• PO:26:087 | Rituximab versus glucocorticoids for IgG4-related disease: a European retrospective multi-center study of 167 patients Marco Lanzillotta¹, Jens Vikse², Elisabetta Goni³, Jasmin Mahajne¹, Veronica Batani¹, Lorenzo Dagna¹, Emanuel Della-Torre¹ | ¹Unit of Immunology, Rheumatology, Allergy, and Rare Disease, IRCCS Ospedale san Raffaele Milano, Italy; ²Department of Rheumatology, Stavanger University Hospital, Stavanger, Norway; ³Department of Medicine II, University Hospital, Ludwig Maximilian University Munich, Munich Germany

  Società Italiana di Reumatologia

  https://doi.org/10.4081/reumatismo.2025.2355

  50

• PO:26:088 | Rheumatologic immune-related adverse events from immune checkpoint inhibitors: a monocentric retrospective study Giulio Fraticelli^1|2, Nicola Farina^1|2, Alessandro Tomelleri^1|2, Marco Matucci Cerinic^1|2, Corrado Campochiaro^1|2, Lorenzo Dagna^1|2. | ¹Unit of Immunology, Rheumatology, Allergy and Rare Diseases UNIRAR, IRCCS San Raffaele Hospital, Milano, Italy; ²Inflammation, Fibrosis and Ageing Initiative INFLAGE, IRCCS San Raffaele Hospital, Milano, Italy.

  Società Italiana di Reumatologia

  https://doi.org/10.4081/reumatismo.2025.2065

  137

• PO:26:092 | Early antiproteinuric effect of voclosporine in patients with lupus nephritis in real life setting: preliminary results from the VoRLiSS (Voclosporine in Real Life Setting Study) Aurora Di Gregorio¹, Marta Calatroni², Marco Allinovi³, Alessandra Bortoluzzi⁴, Giorgio Buscetta⁵, Rossella De Angelis⁶, Ginevra De Marchi⁷, Giacomo Emmi⁸, Pasquale Esposito⁹, Paride Fenaroli¹⁰, Micaela Fredi¹¹, Giovanni Orsolini¹², Giulia Pazzola¹³, Domenico Santoro¹⁴, Andrea Doria¹, Gabriella Moroni², Luca Iaccarino¹ | ¹Azienda Ospedaliera Universitaria Padova, Italy; ²Ospedale IRCCS Humanitas Milano, Italy; ³Azienda Ospedaliero Universitaria Careggi Firenze, Italy; ⁴Azienda Ospedaliero Universitaria di Ferrara, Italy; ⁵Policlinico Universitario Paolo Giaccone Palermo, Italy; ⁶Università Politecnica delle Marche Ancona, Italy; ⁷Università di Udine, Italy; ⁸Università di Trieste, Italy; ⁹Università di Genova, Italy; ¹⁰Unità di Nefrologia AUSL IRCCS di Reggio Emilia, Italy; ¹¹Università di Brescia, Italy; ¹²Università di Verona Verona, Italy; ¹³Università di Reggio Emilia, Italy; ¹⁴Azienda Ospedaliera Universitaria G. Martino di Messina, Italy

  Società Italiana di Reumatologia

  https://doi.org/10.4081/reumatismo.2025.2356

  35

• PO:26:095 | Educational online webinars of European Reference Network on rare and complex connective tissue and musculoskeletal diseases for patients, caregivers and healthcare professionals: six years' experience Emanuele Gotelli^1|2, Rosanna Campitiello^1|3, Eric Hachulla^4|5|6, Vanessa Smith^7|8|9, Joao Eurico Fonseca^10|11, Tadej Avcin^12|13, Gabriele Simonini^14|15, Silvia Aguilera¹⁶, Lisa Matthews¹⁷, Charissa Frank¹⁸, Wiebke Lautré¹⁹, Monica Testoni²⁰, Diana Marinello²⁰, Rosaria Talarico²⁰, Marta Mosca²⁰, Maurizio Cutolo^1|2. | ¹Department of Internal Medicine and Specialties, University of Genova, Genova, Italy; ²IRCCS Ospedale Policlinico San Martino, Genova, Italy; ³Department of Experimental Medicine DIMES, University of Genova, Genova, Italy; ⁴Institute for Translational Research in Inflammation INFINITE, Université de Lille, Lille, France; ⁵INSERM, Lille, France; ⁶Centre de référence des maladies autoimmunes systemiques rares du Nord et Nord-Ouest de France CeRAINO, Lille, France; ⁷Department of Internal Medicine, University of Ghent, Ghent University Hospital, Ghent, Belgium; ⁸Department of Rheumatology, University of Ghent, Ghent University Hospital, Ghent, Belgium; ⁹Unit for Molecular Immunology and Inflammation, Flemish Institute for Biotechnology, Inflammation Research Center, Ghent, Belgium; ¹⁰Centro Hospitalar Universitário Lisboa Norte EPE, Serviço de Reumatologia e Doenças Ósseas Metabólicas Lisboa Portugal; ¹¹Universidade de Lisboa, Unidade de Investigação em Reumatologia, Instituto de Medicina Molecular João Lobo Antunes Lisboa Portugal; ¹²University Children Hospital, University Medical Center Ljubljana, Ljubljana, Slovenia; ¹³University of Ljubljana, Department of Paediatrics, Ljubljana, Slovenia; ¹⁴University of Florence, NEUROFARBA Department, Firenze, Italy; ¹⁵Meyer Children Hospital IRCCS, Rheumatology Unit, Firenze, Italy; ¹⁶Spanish Association for Antiphospholipid Syndrome, Elche, Spain; ¹⁷Relapsing Polychondritis Awareness and Support, Worcester, United Kingdom; ¹⁸Flemish Association for Hereditary Connective Tissue Disorders, Koersel, Belgium; ¹⁹CHU Bordeaux Pellegrin, Centre de Références Maladies Auto-Immunes Systémiques Rares, Bordeaux, France; ²⁰Azienda Ospedaliero Universitaria Pisana, Pisa, Italy.

  Società Italiana di Reumatologia

  https://doi.org/10.4081/reumatismo.2025.2066

  126

• PO:26:096 | From free text to diagnosis: a Natural Language Processing approach for identifying rheumatoid and psoriatic arthritis in the Emergency Department Antonio Tonutti^1|2, Pierandrea Morandini³, Cosimo Faeti³, Nicoletta Luciano^1|2, Saverio D'Amico³, Antonio Voza^1|4, Victor Savevski³, Carlo Selmi^1|2 | ¹Department of Biomedical Sciences, Humanitas University Pieve Emanuele, Milan, Italy; ²Rheumatology and Clinical Immunology, IRCCS Humanitas Research Hospital Rozzano, Milan, Italy; ³Artificial Intelligence Unit, IRCCS Humanitas Research Hospital Rozzano, Milan, Italy; ⁴Emergency Department, IRCCS Humanitas Research Hospital Rozzano, Milan, Italy

  Società Italiana di Reumatologia

  https://doi.org/10.4081/reumatismo.2025.2357

  30

• PO:26:097 | Ultrasound evaluation of temporomandibular disorders: comparative analysis between inflammatory and degenerative patterns in patients with and without rheumatological pathologies Beatrice Maranini¹, Stefano Mandrioli², Fabio Fabbian³, Tommaso Bianchi¹, Manlio Galiè², Marcello Govoni¹ | ¹UO di Reumatologia, Dipartimento di Scienze Mediche, Università di Ferrara; ²UO di Chirurgia Maxillo-Facciale, Dipartimento Testa-Collo, Università di Ferrara; ³Dipartimento di Scienze Mediche, Università di Ferrara, Italy

  Società Italiana di Reumatologia

  https://doi.org/10.4081/reumatismo.2025.2193

  150

• PO:27:105 | Sleep disturbances in patients with polymyalgia rheumatica: correlations with disease activity, fatigue, and glucocorticoid dosage Ilaria Franch¹, Lorenzo Di Sanzo¹, Chiara Castellani², Giulia Bevignani¹, Lucia Colella¹, Veronica Alò¹, Fabrizio Conti¹, Rossana Scrivo¹ | ¹Università La Sapienza, Roma; ²Ospedale San Camillo De Lellis, Rieti, Italy

  Società Italiana di Reumatologia

  https://doi.org/10.4081/reumatismo.2025.2194

  207

• PO:27:106 | Role of histology in interstitial lung involvement of rheumatic diseases in real life scenario Francesca Cozzini^1|2, Francesco Falco¹, Lucia Spaggiari^1|3, Alberto Cavazza¹, Adele Del Giudice^1|2, Lucia Dardani¹, Fabio Brandolino¹, Emanuele Cocchiara¹, Ilaria Chiapparoli¹, Luca Magnani⁴, Gianluigi Bajocchi¹, Carlo Salvarani^1|2, Andreina Manfredi^1|2 | ¹IRCCS Arcispedale Santa Maria Nuova Reggio Emilia, Italy; ²Università degli Studi di Modena e Reggio Emilia Modena, Italy; ³AUSL area NORD Montecchio-Guastalla, Italy; ⁴UOC di Medicina Interna ad Indirizzo Reumatologico, Azienda USL Bologna, Ospedale Maggiore Bologna, Italy

  Società Italiana di Reumatologia

  https://doi.org/10.4081/reumatismo.2025.2358

  40

• PO:27:108 | Delphi consensus on the shared management of patients with rheumatologic and oncologic diseases Luigi De Marco¹, Augusta Ortolan², Antonio Carletto³, Fulvia Ceccarelli⁴, Lorenzo Dagna⁵, Ginevra De Marchi⁶, Ennio Giulio Favalli⁷, Alessandro Inno⁸, Giuseppe Lopalco⁹, Francesco Ciccia¹⁰, Ennio Lubrano¹¹, Luca Quartuccio¹², Immacolata Prevete¹³, Roberta Ramonda¹⁴, Nicola Silvestris¹⁵, Marcello Tiseo¹⁶, Michelina Turri¹, Maria Sole Chimenti¹ | ¹Reumatologia, allergologia e immunologia clinica, dipartimento di medicina dei sistemi, Università di Roma Tor Vergata; ²UOC Reumatologia e immunologia clinica, Fondazione Policlinico Universitario Agostino Gemelli IRCSS, Roma; ³Unità di Reumatologia, Dipartimento di medicina, AOUI università di Verona; ⁴Reumatologia, Dipartimento di Scienze Cliniche, Anestesiologiche Internistiche e Cardiovascolari, Sapienza Università di Roma; ⁵Unità di Immunologia, Reumatologia, Allergologia e malattie rare UnIRar, IRCSS San Raffaele, Milano; ⁶Unità di Reumatologia, Dipartimento di medicina, Azienda Sanitaria Universitaria Integrata, Università di Udine; ⁷Dipartimento di Reumatologia e scienze mediche, Istituto Gaetano Pini, Università di Milano; ⁸Oncologia Medica, IRCCS Ospedale Sacro Cuore Don Calabria, Negrar di Valpolicella (VR); ⁹UOC Reumatologia, Dipartimento di Medicina di Precisione e Rigenerativa e Area Ionica, Università di Bari "Aldo Moro"; ¹⁰Unità di Reumatologia, Dipartimento di Medicina di Precisione, Università della Campania L. Vanvitelli, Napoli; ¹¹Unità di Reumatologia, Università degli Studi del Molise, Campobasso; ¹²SOC Clinica Reumatologica - ASUFC, Dipartimento di Medicina, Università degli Studi di Udine; ¹³UOC Reumatologia Azienda Ospedaliera San Camillo-Forlanini, Roma; ¹⁴UOC di Reumatologia, Dipartimento di Medicina DIMED, Azienda Ospedale Università di Padova; ¹⁵UOC Oncologia Medica e Dipartimento Area Medica - IRCCS Istituto Tumori Giovanni Paolo II, Bari; ¹⁶UOC di Oncologia Medica, Azienda Ospedaliero-Universitaria di Parma, Italy

  Società Italiana di Reumatologia

  https://doi.org/10.4081/reumatismo.2025.2195

  142

• PO:27:112 | The impact of rurality in chronic inflammatory rheumatic diseases in the province of Udine (2014-2023): analysis of clinical outcomes and potential complications Simone Longhino¹, Luigi Castrista², Yvonne Beorchia², Marco Driutti², Elena Treppo¹, Silvio Brusaferro³, Luca Quartuccio¹ | ¹Clinica di Reumatologia, Dipartimento di Medicina Specialistica; ²Istituto di Igiene ed Epidemiologia Valutativa; ³Accreditamento, Gestione del Rischio Clinico e Valutazione delle Performance Sanitarie, ASUFC, Udine, Italy

  Società Italiana di Reumatologia

  https://doi.org/10.4081/reumatismo.2025.2196

  155

• PO:28:116 | Glandular involvement in autoimmune diseases: a spectrum of differential diagnosis Francesca Petrillo¹, Caterina Ricordi¹, Caterina Tomassini¹, Luca Cimino³, Giorgia Citriniti², Fabio Brandolino², Chiara Marvisi¹, Carlo Salvarani¹ | ¹S.C. Reumatologia; ²S.C. Reumatologia; ³S.S.D. Immunologia Oculare, Università di Modena e Reggio Emilia, Arcispedale Santa Maria Nuova, Reggio Emilia, Italy

  Società Italiana di Reumatologia

  https://doi.org/10.4081/reumatismo.2025.2197

  149

• PO:28:126 | Effectiveness of the new AMEL system in the treatment of simple painful shoulder syndrome Antonietta Albanese¹, Emilio Battisti¹, Federico Filippi² | ¹Dipartimento SFTA, Università di Siena, Siena; ²Sanimed, Fisiomed, Vicenza, Italy

  Società Italiana di Reumatologia

  https://doi.org/10.4081/reumatismo.2025.2198

  188

• PO:28:127 | Efficacy of b/ts-DMARDS therapy on depressive and anxiety symptoms in patients with chronic inflammatory joint diseases: preliminary results of a prospective study Nikita Pecani¹, Christian D'Elia¹, Francesca Bartoli¹, Sabrina Aliberti¹, Francesco Rotella², Arianna Ida Altomare², Francesco Vinci², Lorenzo Cortoni², Davide Benedetti³, Camilla Ferrari⁴, Gemma Lepri¹, Silvia Bellando Randone¹, Serena Guiducci¹ | ¹SOD Reumatologia, Dipartimento di Medicina Sperimentale e Clinica, Università degli Studi di Firenze; ²Unità di Psichiatria, Dipartimento di Scienze della Salute, Università degli Studi di Firenze; ³Dipartimento Salute Mentale, USL Umbria, Città di Castello (PG); ⁴Scuola di Scienze della Salute Umana - Università degli Studi di Firenze, Italy

  Società Italiana di Reumatologia

  https://doi.org/10.4081/reumatismo.2025.2199

  177

• PO:28:128 | Rheumatic fever: an atypical case Giovanni Italiano¹, Melania Coscia¹, Arianna Monteforte¹ | ¹AORN S. Anna e S. Sebastiano Caserta, Italy

  Società Italiana di Reumatologia

  https://doi.org/10.4081/reumatismo.2025.2359

  32

• PO:29:131 | Early effect of auricular acupuncture on pain modulation in patients with fibromyalgia: findings from a real-life experience Benedetta Bianchi¹, Edoardo Cipolletta¹, Sonia Farah¹, Fausto Salaffi¹, Marco Di Carlo¹ | ¹Clinica Reumatologica, Università Politecnica delle Marche, ospedale Carlo Urbani Jesi, Ancona, Italy

  Società Italiana di Reumatologia

  https://doi.org/10.4081/reumatismo.2025.2360

  31

• PO:29:132 | Autonomic Dysfunction in Fibromyalgia: A Cross-Sectional Study and Cluster Analysis of Clinical Phenotypes Sergio Del Vescovo¹, Vincenzo Venerito¹, Maria Giannotta¹, Marco Fornaro¹, Greta Giulia Dipietrangelo¹, Andrea Cito¹, Maria Morrone¹, Giuseppe Lopalco¹, Florenzo Iannone¹ | ¹UOC Reumatologia, Policlinico di Bari, DiMePre-J Bari, Italy

  Società Italiana di Reumatologia

  https://doi.org/10.4081/reumatismo.2025.2361

  40

• PO:29:138 | Cetylated fatty acids and fibromyalgia: efficacy and tolerability in a prospective study Anna Capogna¹, Marco Bardelli¹, Luca Cantarini¹, Bruno Frediani¹ | ¹UOC Reumatologia, Dipartimento di Scienze mediche, chirurgiche e neuroscienze, Università degli Studi di Siena, Italy

  Società Italiana di Reumatologia

  https://doi.org/10.4081/reumatismo.2025.2200

  144

• PO:29:139 | Modulation of autonomic dysfunction in fibromyalgia through auricular vagal nerve stimulation: preliminary results Sonia Farah¹, Marco Di Carlo¹, Maria Giovanna Lommano¹, Benedetta Bianchi¹, Piercarlo Sarzi Puttini², Fausto Salaffi¹. | ¹Rheumatology Clinic, Università Politecnica delle Marche, Ospedale Carlo Urbani, Jesi, Italy; ²Rheumatology Unit, IRCCS Galeazzi-Sant Ambrogio Hospital, Milano State University School of Medicine, Milano, Italy.

  Società Italiana di Reumatologia

  https://doi.org/10.4081/reumatismo.2025.2067

  159

• PO:29:141 | Assessing psychosomatic diagnoses and psychological distress in patients with fibromyalgia. The clinical utility of a multidisciplinary approach Sara Ceccatelli¹, Francesca Nacci², Ginevra Fiori², Gemma Lepri², Fiammetta Cosci³, Serena Guiducci² | ¹Dipartimento di Medicina Sperimentale e Clinica; ²Divisione di Reumatologia, Dipartimento di Medicina Sperimentale e Clinica; ³Dipartimento di Scienze della Salute, Università di Firenze, Italy

  Società Italiana di Reumatologia

  https://doi.org/10.4081/reumatismo.2025.2201

  130

• PO:29:144 | Refractory localized pain in fibromyalgia and the importance of differential diagnosis: two cases of Bertolotti’s syndrome and avascular necrosis successfully treated with targeted therapy Andrea Lacarpia¹, Riccardo Terribili¹, Silvia Valentini¹, Marta Fabbroni¹, Stefano Barbagli¹, Stefano Gentileschi¹, Caterina Baldi¹, Luca Cantarini¹, Bruno Frediani¹ | ¹Azienda Ospedaliera Universitaria Senese, Università degli Studi di Siena, Italy

  Società Italiana di Reumatologia

  https://doi.org/10.4081/reumatismo.2025.2202

  151

• PO:29:145 | Fibromyalgia in idiopathic inflammatory myopathies: is it time for rheumatologists to investigate it? Federico Fattorini¹, Michele Diomedi¹, Simone Barsotti², Elenia Laurino³, Chiara Cardelli^1|4, Alessandra Tripoli³, Linda Carli³, Marta Mosca^1|3. | ¹Rheumatology Unit, Department of Clinical and Experimental Medicine, University of Pisa, Pisa, Italy; ²Rheumatology, Versilia Hospital, Viareggio, Italy; ³Rheumatology Unit, AOUP, Pisa, Pisa, Italy; ⁴Department of Medical Biotechnologies, University of Siena, Siena, Italy.

  Società Italiana di Reumatologia

  https://doi.org/10.4081/reumatismo.2025.2068

  145

• PO:30:151 | Clinical characteristics and evolution of juvenile undifferentiated connective tissue diseases: results of a single-center study Nicoletta D'Angelo^1|2, Stefania Costi³, Achille Marino³, Francesco Baldo³, Cecilia Beatrice Chighizola^1|3, Roberto Felice Caporali^1|2|3. | ¹Università degli Studi di Milano, Dipartimento di Scienze Cliniche e di Comunità, Milano, Italy; ²ASST G. Pini-CTO, UOC di Clinica Reumatologica, Milano, Italy; ³ASST G. Pini-CTO, UOC di Clinica Reumatologica Pediatrica, Milano, Italy

  Società Italiana di Reumatologia

  https://doi.org/10.4081/reumatismo.2025.2069

  123

• PO:30:152 | An altered immunometabolic profile characterizes B cells of patients with oligoarticular- and polyarticular- juvenile idiopathic arthritis Emiliano Marasco¹, Angela Aquilani¹, Rebecca Nicolai¹, Maria Isabella Petrone¹, Giusyda Tarantino¹, Ivan Caiello¹, Sabina Barresi², Silvia Magni Manzoni¹, Fabrizio De Benedetti¹ | ¹Unità di Reumatologia, Ospedale Pediatrico Bambino Gesù Roma, Italy; ²UO di Anatomia Patologica, Ospedale Pediatrico Bambino Gesù Roma, Italy

  Società Italiana di Reumatologia

  https://doi.org/10.4081/reumatismo.2025.2362

  37

• PO:30:153 | Long-term outcomes of JIA-associated uveitis: a systematic review and meta-analysis Laura Scagnellato¹, Giacomo Cozzi¹, Matteo Molfese¹, Mariagrazia Lorenzin¹, Jamie Alexander King¹, Gianluca Poncina¹, Stefano Rizzetto¹, Roberta Ramonda¹ | ¹UOC Reumatologia, Dipartimento di Medicina dei Sistemi DIMED, Ospedale Università di Padova, Italy

  Società Italiana di Reumatologia

  https://doi.org/10.4081/reumatismo.2025.2363

  43

• PO:30:155 | The role of nailfold videocapillaroscopy in the assessment of juvenile connective tissue diseases Marco Binda¹, Beatrice Moccaldi¹, Francesca Tirelli², Anna Cuberli¹, Andrea Benini¹, Meneghel Alessandra², Andrea Doria¹, Francesco Zulian², Elisabetta Zanatta¹ | ¹U.O.C. Reumatologia, Dipartimento di Medicina DIMED, Università degli Studi di Padova Padova, Italy; ²U.O.S.D. Reumatologia Pediatrica, Dipartimento per la Salute della Donna e del Bambino, Azienda Ospedaliera di Padova, Italy

  Società Italiana di Reumatologia

  https://doi.org/10.4081/reumatismo.2025.2364

  35

• PO:30:157 | Radiographic assessment of measurable osteoarticular damage in juvenile idiopathic arthritis (JIA) patients transitioning to adult care Serena Pastore⁴, Marta Klanmjsceck³, Andrea Guiotto¹, Laura De Nardi^5|6, Alessia Pin⁴, Lorenzo Cereser^1|2, Andrea Taddio^3|4, Luisa Occhipinti¹, Luca Quartuccio^1|2, Alberto Tommasini^3|4, Alen Zabotti² | ¹Università degli Studi di Udine Udine, Italy; ²Ospedale Santa Maria della Misericordia Udine, Italy; ³Università degli Studi di Trieste Trieste, Italy; ⁴IRCCS Materno Infantile Burlo Garofolo Trieste, Italy; ⁵Università Tor Vergata Roma, Italy; ⁶Ospedale Pediatrico Bambino Gesù Roma, Italy

  Società Italiana di Reumatologia

  https://doi.org/10.4081/reumatismo.2025.2365

  33

• PO:30:160 | A rare case of juvenile systemic sclerosis Marta Arese^1|2, Francesco Baldo³, Stefania Costi³, Achille Marino³, Cecilia Chighizola^1|3, Roberto Felice Caporali^1|2 | ¹Azienda Ospedaliera Universitaria Senese, Università degli Studi di Siena; ²Reumatologia Clinica, ASST Gaetano Pini-CTO, Milano, Italy

  Società Italiana di Reumatologia

  https://doi.org/10.4081/reumatismo.2025.2203

  228

• PO:31:161 | First-line diagnostic tests to intercept primary heart involvement in systemic sclerosis: clinical associations from the SPRING-SIR registry Antonio Tonutti^1|2, Francesca Motta^1|2, Rossella De Angelis³, Valeria Riccieri⁴, Silvia Laura Bosello⁵, Fabio Cacciapaglia⁶, Veronica Codullo⁷, Giacomo De Luca⁸, Francesca Ingegnoli⁹, Dilia Giuggioli¹⁰, Clodoveo Ferri¹⁰, Marco Matucci-Cerinic⁸, Carlo Selmi^1|2, Maria De Santis^1|2 | ¹Department of Biomedical Sciences, Humanitas University Pieve Emanuele, Milan, Italy; ²Rheumatology and Clinical Immunology, IRCCS Humanitas Research Hospital Rozzano, Milan, Italy; ³Università Politecnica delle Marche Ancona, Italy; ⁴Università degli Studi di Roma La Sapienza Roma, Italy; ⁵Università Cattolica del Sacro Cuore Roma, Italy; ⁶Università degli Studi di Bari Aldo Moro Bari, Italy; ⁷Reumatologia, Fondazione IRCCS Policlinico San Matteo Pavia, Italy; ⁸Università Vita-Salute San Raffaele Milano, Italy; ⁹Università degli Studi di Milano, Italy; ¹⁰Università degli Studi di Modena e Reggio Emilia, Italy

  Società Italiana di Reumatologia

  https://doi.org/10.4081/reumatismo.2025.2366

  32

• PO:31:163 | Safety and tolerability of home-based prostacyclin analogue therapy in vascular manifestations of the scleroderma spectrum: results of a monocentric study Alice Dionisi¹, Lucrezia Verardi², Annacarla Finucci², Paola Volpe², Anna Cinzia Raspa², Paola Cipriani¹, Raffaele Zicolella² | ¹Reumatologia,Dipartimento di Sscienze Cliniche Applicate e Biotecnologiche, Università degli Studi dell'Aquila; ²UOC Reumatologia, Ospedale Civile di Pescara, Italy

  Società Italiana di Reumatologia

  https://doi.org/10.4081/reumatismo.2025.2204

  156

• PO:31:165 | Prevalence and incidence of skin telangectasia and their association with clinical features: analysis of the European Scleroderma Trials and Research cohort Gemma Lepri¹, Lorenzo Tofani², Silvia Bellando Randone¹, Veronica Batani³, Paolo Airò⁴, Patricia Carreira⁵, Joerg Henes⁶, Alexandra Balbir Gurman⁷, Florenzo Iannone⁸, Antonella Marcoccia⁹, Luc Mouthon¹⁰, Branimir Anic¹¹, Carolina De Souza Müller¹², Armine Haroyan¹³, Ana Cristina Cordeiro¹⁴, Serena Guiducci And Eustar Coll¹. | ¹University of Florence, Dept of Experimental and Clinical Medicine, AOU Careggi, Division of Rheumatology Florence Italy; ²University of Florence, Dept of Statistics, Informatics, Applications, Florence, Italy; ³Unit of Immunology, Rheumatology, Allergy and Rare Diseases ^UnIRAR, IRCCS San Raffaele, Milano, Italy; ⁴Scleroderma Unit, UOC Rheumatology and Clinical Immunology, ASST Spedali Civili, Brescia, Italy; ⁵Dept of Rheumatology, 12 de Octubre University Hospital, Madrid, Spain; ⁶Centre for Interdisciplinary Rheumatology, Immunology and autoimmune diseases INDIRA, University Hospital Tuebingen, Tuebingen, Germany; ⁷Rheumatology Institute, Rambam Health Care Campus Haifa Israel; ⁸Dept of Precision and Regenerative Medicine and Ionian Area, University of Bari, Bari, Italy; ⁹Interdisciplinary Reference Center for Systemic Sclerosis ^CRIIS Sandro Pertini Hospital, Rome, Italy; ¹⁰Dept of Internal Medicine, Cochin Hospital, Paris Cité University, Paris, France; ¹¹Div Clinical Immunology and Rheumatology, Dept Internal Medicine, School of Medicine, University Hospital Center Zagreb, Zagreb, Croatia; ¹²Rheumatology Division, Hospital de Clínicas da Universidade Federal do Parana, Curitiba, Brazil; ¹³Dept of Rheumatology, Yerevan State Medical University of Armenia, Yerevan, Armenia; ¹⁴Servico Reumatologia Hospital Garcia de Orta Almada, Almada, Portugal.

  Società Italiana di Reumatologia

  https://doi.org/10.4081/reumatismo.2025.2070

  149

• PO:31:166 | S'/PAPs ratio in systemic sclerosis: a promising non-invasive index for early detection and prognosis of pulmonary hypertension. A step toward more accurate screening? Marco De Pinto¹, Amelia Spinella¹, Pierluca Macripò², Alessia Laneri¹, Benedetta Bongiovanni¹, Maria Grazia Malandra¹, Martina Orlandi^1-3, Gianluca Pagnoni², Arianna Maini², Rosario Rossi^2-4, Clodoveo Ferri¹, Francesca Coppi^2-3, Dilia Giuggioli^1-3. | ¹Rheumatology Unit, Azienda Ospedaliero-Universitaria Policlinico di Modena, University of Modena and Reggio Emilia, Modena, Italy; ²Cardiology Division, Azienda Ospedaliero-Universitaria Policlinico di Modena, Modena, Italy; ³Department of Medical and Surgical Sciences for Children and Adults, University of Modena and Reggio Emilia, Modena, Italy; ⁴Department of Biomedical, Metabolic and Neural Sciences, University of Modena and Reggio Emilia, Modena, Italy.

  Società Italiana di Reumatologia

  https://doi.org/10.4081/reumatismo.2025.2071

  139

• PO:31:167 | Increased M2 pro-fibrotic marker expression in circulating monocytes and cultured monocyte-derived macrophages in systemic sclerosis patients with progressive interstitial lung disease Vanessa Smith^1|2, Stefano Soldano³, Rosanna Campitiello^3|5, Emanuele Gotelli^3|4, Paola Montagna³, Elvis Hysa^3|5, Tamara Vojinovic^3|4, Carmen Pizzorni^3|4, Sabrina Paolino^3|4, Alberto Sulli^3|4, Maurizio Cutolo^3|4. | ¹Department of Internal Medicine and Department of Rheumatology, Ghent University Hospital, Ghent, Belgium; ²Unit for Molecular Immunology and Inflammation, VIB Inflammation Research Centre, Ghent, Belgium; ³Laboratory of Experimental Rheumatology and Academic Division of Clinical Rheumatology, Department of Internal Medicine, Genova, Italy; ⁴IRCCS Ospedale Policlinico San Martino, Genova, Italy; ⁵Department of Experimental Medicine DIMES, University of Genova, Genova, Italy.

  Società Italiana di Reumatologia

  https://doi.org/10.4081/reumatismo.2025.2072

  133

• PO:31:168 | Risk factors for cancer in systemic sclerosis, impact on disease phenotype and prognosis, and proposal of machine learning-based personalized screening strategies: insights from an EUSTAR study Antonio Tonutti^1|2, Francesca Motta^1|2, Stefano Erba^1|2, Britta Maurer³, Cristiana Sieiro Santos³, Duygu Temiz Karadag³, Elena Rezus³, Elisabetta Zanatta³, Fabiola Atzeni³, Francesco Benvenuti³, Gabor Kumanovics³, Gabriella Szucs³, Gianluca Moroncini³, Gonçalo Boleto³, Leila Caillault³, Lilian Maria Lopez Nunez³, Masataka Kuwana³, Massimiliano Limonta³, Maurizio Cutolo³, Oliver Distler³, Radim Bevcar³, Roberto Giacomelli³, Rossella De Angelis³, Serena Guiducci³, Stefano Stano³, Valeria Riccieri³, Yasser El Miedany³, Sophie Blaise³, Carlo Selmi^1|2, Maria De Santis^1|2 | ¹Department of Biomedical Sciences, Humanitas University Pieve Emanuele, Milan, Italy; ²Rheumatology and Clinical Immunology, IRCCS Humanitas Research Hospital Rozzano, Milan, Italy; ³EUSTAR collaborators EUSTAR * OTHER

  Società Italiana di Reumatologia

  https://doi.org/10.4081/reumatismo.2025.2367

  21

• PO:31:169 | From Crisis to Chronicity: A Real-World Study of Renal Dysfunction in Systemic Sclerosis Stefano Stano¹, Fabio Cacciapaglia^1|2, Giorgia Campanale¹, Simone Perniola¹, Maria Morrone¹, Andrea Cito¹, Vincenzo Venerito¹, Maria Grazia Anelli¹, Giuseppe Lopalco¹, Florenzo Iannone¹ | ¹Rheumatology Unit - Department of Precision and Regenerative Medicine, Jonian Area DiPReMeJ, University of Bari Bari, Italy; ²Rheumatology Service, Internal Medicine Unit F. Miulli General Hospital, Department of Medicine and Surgery, LUM Casamassima, Italy

  Società Italiana di Reumatologia

  https://doi.org/10.4081/reumatismo.2025.2368

  18

• PO:31:171 | Uncovering subclinical cardiac involvement in VEDOSS: An echocardiographic driven study Eugenio Capparelli¹, Eleonora Zaccara¹, Irene Rota², Sara Facetti², Daniela Bompane¹, Laura Castelnovo¹, Antonino Mazzone³, Paola Faggioli¹ | ¹UOC Reumatologia, ASST Ovest-Milanese, Legnano Milano Italy; ²UOC Cardiologia, ASST Ovest-Milanese, Legnano Milano, Italy; ³UOC Medicina Interna, ASST Ovest-Milanese, Legnano, Milano, Italy

  Società Italiana di Reumatologia

  https://doi.org/10.4081/reumatismo.2025.2369

  8

• PO:31:172 | Age and timing of onset of Raynaud's phenomenon and first non-Raynaud sign/symptom as prognostic factors in systemic sclerosis: a retrospective analysis from the systemic sclerosis progression investigation registry of the Italian Society for Rheumatology Silvia Peretti¹, Cosimo Bruni², Silvia Laura Bosello³, Fabio Cacciapaglia^4-5, Corrado Campochiaro^6-7, Veronica Codullo⁸, Lorenzo Dagna^6-7, Rossella De Angelis⁹, Giacomo De Luca^6-7, Dilia Giuggioli¹⁰, Serena Guiducci¹, Florenzo Iannone⁴, Francesca Ingegnoli¹¹, Valeria Riccieri¹², Marco Matucci Cerinic^6-7, Clodoveo Ferri^10-13, Silvia Bellando Randone¹. | ¹Division of Rheumatology, Scleroderma Unit, Department of Experimental and Clinical Medicine, University of Florence, AO, Firenze, Italy; ²Division of Rheumatology, University Hospital Zurich, University of Zurich, Zurich, Switzerland; ³Rheumatology Division, Catholic University of the Sacred Heart, Fondazione Policlinico Universitario A. Gemelli- IRCCS, Roma, Italy; ⁴Rheumatology Unit, Department of Precision and Regenerative Medicine-Ionian Area, University of Bari Aldo Moro, Bari, Italy; ⁵Reumatology Service, Internal Medicine Unit F.Miulli General Hospital, Acquaviva delle Fonti -Department of Medicine a, Bari, Italy; ⁶Unit of Immunology, Rheumatology, Allergy and Rare Diseases UnIRAR, Inflammation, Fibrosis and Ageing initiative INFL, Milano, Italy; ⁷Vita-Salute San Raffaele University, Milano, Italy; ⁸Department of Internal Medicine and Therapeutics, Università di Pavia, Italy; Division of Rheumatology, Fondazione IRCCS, Pavia, Italy; ⁹Rheumatology Unit, Department of Clinical and Molecular Sciences, Polytechnic University of Marche, Ancona, Italy; ¹⁰Rheumatology Unit, School of Medicine, University of Modena and Reggio Emilia, Modena, Italy; ¹¹Division of Clinical Rheumatology, ASST Pini, Dept. of Clinical Sciences and Community Health, Research Center for Adul, Milano, Italy; ¹²Department of Rheumatology, Sapienza University of Rome, Roma, Italy; ¹³Rheumatology Clinic Madonna dello Scoglio Crotonei, Crotone, Italy.

  Società Italiana di Reumatologia

  https://doi.org/10.4081/reumatismo.2025.2073

  155

• PO:31:173 | Methotrexate monotherapy in early systemic sclerosis: a real-life monocentric Italian experience Claudia Iannone^1|2, Ilaria Magi^1|2, Antonina Minniti², Giuseppe Armentaro², Silvia Cavalli^1|2, Manuel Sette^1|2, Laura Giudice^1|2, Maria Rosa Pellico^1|2, Cristina Bochicchio^1|2, Roberto Felice Caporali^1|2, Nicoletta Del Papa^1|2. | ¹Dipartimento di Scienze Cliniche e di Comunità, Università degli Studi di Milano, Milano, Italy; ²Dipartimento di Reumatologia e Scienze Mediche, ASST G. Pini-CTO, Milano, Italy.

  Società Italiana di Reumatologia

  https://doi.org/10.4081/reumatismo.2025.2074

  141

• PO:31:174 | Increased frequency of anti-RNA polymerase 3 antibodies in patients with systemic sclerosis and silicone breast implants: a multicentre study from the international European Scleroderma Trials and Research cohort Maria Grazia Lazzaroni¹, Yolanda Braun-Moscovici², Elda Piovani¹, Claudia Barison¹, Liala Moschetti¹, Veronica Batani³, Corrado Campochiaro³, Michal Tomcik⁴, Francesca Motta⁵, Maria De Santis⁵, Petros P. Sfikaki⁶, Masataka Kuwana⁷, Brigitte Granel⁸, Roberta Foti⁹, Virginia Berlingiero¹⁰, Joana Caetano¹¹, Yannick Allanore¹², Alexandra Balbir-Gurman², Marco Matucci Cerinic³, Franco Franceschini¹, Paolo Airò¹. | ¹ASST Spedali Civili of Brescia, University of Brescia, Brescia, Italy; ²Rambam Health Care Campus, Rappaport Faculty of Medicine, Technion-Israeli Institute of Tecnology, Haifa, Israel; ³Vita-Salute San Raffaele University, San Raffaele Hospital, Milano, Italy; ⁴Institute of Rheumatology, Praga, Czech Republic; ⁵IRCCS Humanitas Research Hospital; Humanitas University, Milano, Italy; ⁶Joint Rheumatology Program, Medical School, National Kapodistrian University of Athens Atene GREECE; ⁷Nippon Medical School Hospital Tokyo Japan; ⁸Hôpital Nord de Marseille; Aix-Marseille Université Marsiglia France; ⁹AOU Policlinico G. Rodolico San Marco, Catania, Italy; ¹⁰Azienda Ospedaliera Universitaria Senese, Siena, Italy; ¹¹Fernando Fonseca Hospital, Amadora, Portugal; ¹²Université Paris Cité, Cochin Hospital, Parigi, France.

  Società Italiana di Reumatologia

  https://doi.org/10.4081/reumatismo.2025.2075

  141

• PO:31:175 | Characterizing gastrointestinal involvement in systemic sclerosis: insights from the national systemic sclerosis progression investigation registry of the Italian Society of Rheumatology Francesco Bonomi¹, Cosimo Bruni^1|2, Silvia Laura Bosello³, Fabio Cacciapaglia^4|5, Corrado Campochiaro⁶, Roberto Caporali⁷, Veronica Codullo⁸, Maria Antonietta D'Agostino³, Lorenzo Dagna⁶, Rossella De Angelis⁹, Giacomo De Luca⁶, Dilia Giuggioli¹⁰, Serena Guiducci¹, Florenzo Iannone⁴, Francesca Ingegnoli⁷, Carlomaurizio Montecucco⁸, Valeria Riccieri¹¹, Clodoveo Ferri¹⁰, Marco Matucci Cerinic⁶, Silvia Bellando Randone¹. | ¹Scleroderma Unit, Division of Rheumatology AOUC, and Department of Experimental and Clinical Medicine, Uni. of Florence, Firenze, Italy; ²Department of Rheumatology, University Hospital Zurich, University of Zurich Zurigo Switzerland; ³UOC of Rheumatology and Clinical Immunology, Catholic University of the Sacred Heart, Fondazione Policlinico A. Gemelli, Roma, Italy; ⁴Rheumatology Unit, Department of Emergency Surgery and Organ Transplantations, University of Bari, Bari, Italy; ⁵Rheumatology Service, F. Miulli General Hospital - Department of Medicine and Surgery, LUM 'G. De Gennaro', Casamassima, Italy; ⁶Unit of Immunology, Rheumatology, Allergy and Rare Diseases and Inflammation, fibrosis and ageing initiative, UniSR, Milano, Italy; ⁷Division of Clinical Rheumatology, ASST Pini and Università degli studi di Milano, Milano, Italy; ⁸Department of Rheumatology, Policlinico San Matteo, Pavia, Italy; ⁹Rheumatology Unit, Department of Clinical and Molecular Sciences, Polytechnic University of Marche, Ancona, Italy; ¹⁰Rheumatology Unit, School of Medicine, University of Modena and Reggio Emilia, Modena, Italy; ¹¹Department of Rheumatology, Sapienza University of Rome, Roma, Italy.

  Società Italiana di Reumatologia

  https://doi.org/10.4081/reumatismo.2025.2076

  151

• PO:32:176 | Outcomes of upfront combination vs monotherapy with rituximab or mycophenolate mofetil for systemic sclerosis interstitial lung disease: results from a European Scleroderma Trials and Research cohort study Devis Benfaremo¹, Corrado Campochiaro², Gábor Kumánovics³, Christina Bergmann⁴, Elisabetta Zanatta⁵, David Launay⁶, Serena Guiducci⁷, Mickael Martin⁸, Carolina De Souza Müller⁹, Carlomaurizio Montecucco¹⁰, Luc Mouthon¹¹, Gabriella Szucs¹², Kastriot Kastrati¹³, Marie-Elise Truchetet¹⁴, Madelon Vonk¹⁵, Francesco Del Galdo¹⁶, Marco Matucci-Cerinic², Gianluca Moroncini¹, Yannick Allanore¹⁷. | ¹Department of Clinical and Molecular Sciences, Marche Polytechnic University, Marche University Hospital, Ancona, Italy; ²Vita-Salute San Raffaele University, San Raffaele Hospital, Milano, Italy; ³University of Pécs, Department Of Rheumatology And Immunology, Pécs, Hungary; ⁴University Hospital Erlangen, Department Internal Medicine 3, Erlangen, Germany; ⁵Padova University Hospital, Rheumatology Unit, Padova, Italy; ⁶Univ. Lille, Inserm, CHU Lille, Department of Internal Medicine and Clinical Immunology, Lille, France; ⁷University of Florence, Azienda Ospedaliera Universitaria Careggi, Firenze, Italy; ⁸Poitiers University Hospital, Department of Internal Medicine Poitiers France; ⁹Hospital de Clinicas da Universidade Federal do Parana Curitiba Brazil; ¹⁰Università di Pavia e IRCCS Fondazione Policlinico S. Matteo, Pavia, Italy; ¹¹Hôpital Cochin, Department of Internal Medicine, Paris, France; ¹²University of Debrecen, Faculty of Medicine, Department of Rheumatology, Debrecen, Hungary; ¹³Medical University of Vienna, Department of Medicine III, Division of Rheumatology, Vienna, Austria; ¹⁴CHU de Bordeaux, Rheumatology department, Bordeaux, France; ¹⁵Radboudumc, Department of Rheumatology Nijmegen The Netherlands; ¹⁶Leeds Raynauds and Scleroderma Program, NIHR Biomedical Research Centre, Leeds, United Kingdom; ¹⁷Université Paris Cité, Cochin Hospital, Rheumatology Department, Paris, France.

  Società Italiana di Reumatologia

  https://doi.org/10.4081/reumatismo.2025.2077

  152

• PO:32:178 | Effectiveness of oral anticoagulants in precapillary pulmonary hypertension associated with systemic sclerosis: a EUSTAR cohort study Nicola Farina¹, Silvia Bellando-Randone¹, Hilde Jenssen-Bjørkekjær², David Launay³, Patricia Carreira⁴, Paolo Airò⁵, Serena Guiducci¹, Dilia Giuggioli⁶, Gabriela Riemekasten⁷, Carmen-Pilar Simeón Aznar⁸, Christina Bergmann⁹, Elise Siegart¹⁰, Ivan Castellví¹¹, Lesley Ann Saketkoo¹², Jeska De Vries-Bouwstra¹³, Philipp Klemm¹⁴, Ulf Müller-Ladner¹⁴, Alexandra Balbir-Gurman¹⁵, Vanessa Smith¹⁶, Florenzo Iannone¹⁷, Luca Idolazzi¹⁸, Christopher Denton¹⁹, Edoardo Rosato²⁰, Britta Maurer¹, Yannick Allanore¹, Yoshiya Tanaka¹, Elisabetta Zanatta¹, Oliver Distler¹, Marco Matucci-Cerinic¹, Cosimo Bruni¹ | ¹Department of Experimental and Clinical Medicine, Scleroderma Unit, Division of Rheumatology, University of Florence, Az Firenze, Italy; ²Department of Rheumatology, Hospital of Southern Norway Kristiansand, Norway; ³National Reference Center for Pulmonary Arterial Hypertension Pulmotension Lille, France; ⁴Hospital Universitario 12 de Octubre, Rheumatology Department Madrid Spain; ⁵ASST Spedali Civili of Brescia, University of Brescia, Rheumatology and Clinical Immunology Unit Brescia, Italy; ⁶Scleroderma Unit, Rheumatology Unit, University Hospital of Modena and Reggio Emilia Modena, Italy; ⁷Universitätsklinikum Schleswig-Holstein, Klinik für Rheumatologie und klinische Immunologie Lübeck Germany; ⁸Hospital Universitario Vall d'Hebron, Department of Internal Medicine, Systemic Autoimmune Diseases Unit Barcelona Spain; ⁹University Hospital Erlangen, Department Internal Medicine 3 Erlangen Germany; ¹⁰Charité University Hospital, Department of Rheumatology Berlin Germany; ¹¹Hospital de la Santa Creu i Sant Pau Baercelona Spain; ¹²New Orleans Scleroderma and Sarcoidosis Patient Care and Research Center New Orleans, USA; ¹³Leiden University Medical Center, Department of Rheumatology Leiden, The Netherlands; ¹⁴JLU Giessen, Campus Kerckhoff, Department of Rheumatology and Clinical Immunology Center Bad Nauheim Germany; ¹⁵Rambam Health Care Campus, Rheumatology Institute Haifa, Israel; ¹⁶University of Ghent, Department of Rheumatology Ghent, Belgium; ¹⁷Rheumatology DiMePReJ, University of Bari, School of Medicine Bari, Italy; ¹⁸University of Verona, Section of Rheumatology, Department of Medicine Verona, Italy; ¹⁹Royal Free London and University College London Medical School, Centre for Rheumatology London, United Kingdom; ²⁰Sapienza University of Rome, Department of Translational and Precision Medicine Azienda Ospedaliero-Universitaria Policl Roma, Italy

  Società Italiana di Reumatologia

  https://doi.org/10.4081/reumatismo.2025.2370

  15

• PO:32:180 | Clinical and hemodynamic profile of patients with SSC-PAH with and without pulmonary veno-occlusive disease: a single-center study Anna Cuberli¹, Michele Strosio², Alessandro Magi², Beatrice Moccaldi¹, Marco Binda¹, Andrea Benini¹, Andrea Doria¹, Martina Perazzolo Marra², Giulia Famoso², Laura De Michieli², Elisabetta Zanatta^1|2 | ¹UOC Reumatologia, DIDAS Medicina Dei SIstemi, Azienda Ospedale Università di Padova; ²UOC Cardiologia, DIDAS Medicina Dei Sistemi, Azienda Ospedale Università di Padova, Italy

  Società Italiana di Reumatologia

  https://doi.org/10.4081/reumatismo.2025.2205

  118

• PO:32:181 | Digital ulcers predict enhanced Peak Systolic Velocities at internal and external Carotid in Systemic Sclerosis Patients Eugenio Capparelli¹, Francesco Lapia², Luca Clerici², Eleonora Zaccara¹, Giusy Cinzia Moltisanti², Francesca Capelli², Daniela Bompane¹, Paola Faggioli¹, Antonino Mazzone² | ¹UOC Reumatologia, ASST Ovest Milanese, Legnano, Milano, Italy; ²UOC Medicina Interna, ASST Ovest Milanese, Legnano, Milano, Italy

  Società Italiana di Reumatologia

  https://doi.org/10.4081/reumatismo.2025.2371

  14

• PO:32:182 | Disease characteristics of anti-centromere positive systemic sclerosis patients and risk factors for organ involvement: data from the EUSTAR cohort Corrado Campochiaro¹, Jelena Colic², Del Papa Nicoletta³, Oliver Distler⁴, Serena Guiducci⁵, Florenzo Iannone⁶, David Launay⁷, Yair Levy⁸, Britta Maurer⁹, Arsene Mekinian¹⁰, Predrag Ostojic², Gabriela Riemekasten¹¹, Petros Sfikakis¹², Bojana Stamenkov¹³, Ulrich Walker¹⁴, Marie Elise Truchetet¹⁵, Madelon Vonk¹⁶, Francesco Del Galdo¹⁷, Giacomo De Luca¹, Lorenzo Dagna¹, Marco Matucci Cerinic¹, Yannick Allanore¹⁸ | ¹IRCCS San Raffaele Hospital; Vita Salute San Raffaele University Milan, Italy; ²University of Belgrade Belgrade, Serbia; ³UOC Reumatologia Clinica, ASST G. Pini CTO Milan, Italy; ⁴University Hospital Zurich Zurich, Switzerland; ⁵Department of Rheumatology, University of Florence Florence, Italy; ⁶Rheumatology Unit Bari, Italy; ⁷CHU Lille Lille, France; ⁸Department of Medicine Kfar Saba, Israel; ⁹Department for BioMedical Research, University of Bern Bern, Switzerland; ¹⁰Service de medecine interne Paris, France; ¹¹Department of Rheumatology University of Lubeck Lubeck Germany; ¹²National and Kapodistrian University of Athens Athens, Greece; ¹³University School of Medicine, Nis Nis, Serbia; ¹⁴University Hospital Basel, Basel Basel, Switzerland; ¹⁵Bordeaux Hospital and University Bordeaux, France; ¹⁶Radboud University Nijmegen Medical Centre, Nijmegen, The Netherlands; ¹⁷Leeds Institute of Rheumatic and Muskuloskeletal Medicine Leeds, United Kingdom; ¹⁸Cochin Hospital Paris, France

  Società Italiana di Reumatologia

  https://doi.org/10.4081/reumatismo.2025.2372

  16

• PO:32:183 | Innovative use of integra dermal regeneration template on systemic sclerosis digital ulcers: a case report Elena Vanni¹, Martina Orlandi^1|2, Amelia Spinella², Valentina Pinto³, Massimo Pinelli³, Dilia Giuggioli^1|2 | ¹Reumatologia, Università di Modena e Reggio Emilia; ²Reumatologia, Azienda Ospedaliero-Universitaria Policlinico di Modena; ³Chirurgia Plastica, Università di Modena e Reggio Emilia e Azienda Ospedaliero-Universitaria, Policlinico di Modena, Italy

  Società Italiana di Reumatologia

  https://doi.org/10.4081/reumatismo.2025.2206

  142

• PO:32:184 | Assessing the burden of Sars-Cov2 in systemic sclerosis-related interstitial lung disease patients: functional, clinical and therapeutic outcomes from an Italian cohort, a retrospective study Andrea Cito¹, Greta Giulia Dipietrangelo¹, Daniele V. A. Sabella¹, Marco Fornaro¹, Fabio Cacciapaglia¹, Giuseppe Lopalco¹, Florenzo Iannone¹. | ¹AOUC Policlinico di Bari - Reumatologia Universitaria, Bari, Italy.

  Società Italiana di Reumatologia

  https://doi.org/10.4081/reumatismo.2025.2078

  159

• PO:32:185 | Deep-learning analysis of high-resolution computed tomography images predicts progression and mortality in systemic sclerosis related interstitial lung disease Valentina Boni¹, Rosa D'Abronzo², Piergiacomo Cerasuolo¹, Lucio Calandriello², Giuseppe Cicchetti², Gerlando Natalello¹, Bruno Iovene⁵, Francesco Varone⁵, Giacomo Sgalla⁵, Luca Richeldi⁵, Anna Rita Larici^2|4, Maria Antonietta D'Agostino^1|3, Silvia Laura Bosello^1|3, Enrico De Lorenzis¹. | ¹Division of Rheumatology and Clinical Immunology Catholic Univeristy of the Sacred Heart, Rome, Italy; ²Department of Diagnostic Imaging, Oncological Radiotherapy and Hematology, Diagnostic Imaging Area, Catholic University, Rome, Italy; ³Department of Geriatric and Orthopaedic Sciences, Catholic Univeristy of the Sacred Heart, Rome, Italy; ⁴Department of Radiological and Hematological Sciences, Section of Radiology, Catholic Univeristy of the Sacred Heart, Rome, Italy; ⁵Division of Pulmonary Medicine, Catholic University of the Sacred Heart, Roma, Italy.

  Società Italiana di Reumatologia

  https://doi.org/10.4081/reumatismo.2025.2079

  134

• PO:32:187 | AI-assisted reading outperforms visual scoring of pulmonary CT scans to predict interstitial lung disease progression in systemic sclerosis Francesca Motta¹, Antonio Tonutti¹, Federica Catapano², Gianluca Sellaro², Francesco Amati³, Anna Stainer³, Calogero Messana², Stefano Erba¹, Stefano Aliberti³, Marco Francone², Carlo Selmi¹, Maria De Santis¹ | ¹Humanitas University and IRCCS Humanitas Research Hospital, Department of Rheumatology and Clinical Immunology Rozzano, Milan, Italy; ²IRCCS Humanitas Research Hospital, Department of Radiology Rozzano, Milan, Italy; ³IRCCS Humanitas Research Hospital, Respiratory Unit Rozzano, Milan, Italy

  Società Italiana di Reumatologia

  https://doi.org/10.4081/reumatismo.2025.2373

  19

• PO:32:189 | Salivary gland alterations in systemic sclerosis: a comprehensive ultrasound study and autoantibody correlation Bixio Riccardo¹, Francesca Pistillo¹, Luca Idolazzi¹, Francesca Nava¹, Beatrice Gabrielli¹, Emanuela Perrucchini², Ombretta Viapiana¹, Maurizio Rossini¹. | ¹Rheumatology Unit, University of Verona VERONA Italy; ²WellAgeing DESENZANO DEL GARDA Italy.

  Società Italiana di Reumatologia

  https://doi.org/10.4081/reumatismo.2025.2080

  163

• PO:33:190 | Travel distance to tertiary healthcare reflects disease severity and medication access in systemic sclerosis patients: insights from the Italian systemic sclerosis progression investigation registry of the Italian Society of Rheumatology Camilla Teresa Magnanimi¹, Enrico De Lorenzis¹, Gerlando Natalello¹, Fabio Cacciapaglia², Rossella De Angelis³, Edoardo Cipolletta³, Maria Antonietta D'Agostino¹, Veronica Cudullo⁴, Giacomo De Luca⁵, Dilia Giuggioli⁶, Francesca Ingegnoli⁷, Valeria Riccieri⁸, Lorenzo Dagna⁵, Fiorenzo Iannone⁹, Clodoveo Ferri⁶, Marco Matucci Cerinic⁵, Silvia Laura Bosello¹. | ¹Division of Rheumatology and Clinical Immunology, Catholic University of the Sacred Heart, Fondazione Policlinico Univer, Roma, Italy; ²Department of Medicine and Surgery, LUM University Giuseppe De Gennaro Casamassima e Rheumatology Service Miulli Ge, Bari, Italy; ³Rheumatology Unit - Department of Clinical and Molecular Sciences, Polytechnic University of Marche, Ancona, Italy; ⁴Department of Rheumatology, Policlinico San Matteo, Pavia, Italy; ⁵Unit of Immunology, Rheumatology, Allergy and Rare Diseases ^UnIRAR, IRCCS San Raffaele Scientific Institute, Vita-Salu, Milano, Italy; ⁶Rheumatology Unit, School of Medicine, University of Modena and Reggio Emilia, Modena, Italy; ⁷Division of Clinical Rheumatology, ASST Pini, Dept. of Clinical Sciences e Community Health, Research Center for Adult a, Milano, Italy; ⁸Department of Rheumatology, La Sapienza University of Rome, Roma, Italy; ⁹Rheumatology Unit, Department of Precision and Regenerative Medicine and Ionian Area, University of Bari, Bari, Italy.

  Società Italiana di Reumatologia

  https://doi.org/10.4081/reumatismo.2025.2081

  160

• PO:33:191 | Evaluation of the living with pulmonary fibrosis questionnaire in patients with systemic sclerosis associated interstitial lung disease: monocentric results Claudia Barison¹, Elda Piovani¹, Eleonora Pedretti¹, Eleonora Pazzi¹, Liala Moschetti¹, Ilaria Cavazzana¹, Franco Franceschini¹, Maria Grazia Lazzaroni¹, Paolo Airò¹. | ¹Rheumatology and Clinical Immunology, Scleroderma Unit, ASST Spedali Civili of Brescia, University of Brescia, Brescia, Italy.

  Società Italiana di Reumatologia

  https://doi.org/10.4081/reumatismo.2025.2082

  133

• PO:33:192 | Hand Microvascular Damage Is Associated with Hand Bone Loss in Systemic Sclerosis Rosanna Campitiello^1|3, Sabrina Paolino^1|2, Andrea Casabella^1|2, Giulia Davoli^1|2, Elisa Caratto^1|2, Emanuele Gotelli^1|2, Elvis Hysa^1|2, Carmen Pizzorni^1|2, Vanessa Smith^4|5, Alberto Sulli^1|2, Maurizio Cutolo^1|2 | ¹1. Laboratory of Experimental Rheumatology and Academic Division of Clinical Rheumatology, Department of Internal Medic Genova, Italy; ²IRCCS Ospedale Policlinico San Martino Genova, Italy; ³Department of Experimental Medicine DIMES, University of Genova Genova, Italy; ⁴Department of Internal Medicine and Department of Rheumatology, Ghent University ^Hospital Ghent, Belgium; ⁵Unit for Molecular Immunology and Inflammation, VIB Inflammation Research Centre, Ghent, Belgium

  Società Italiana di Reumatologia

  https://doi.org/10.4081/reumatismo.2025.2374

  22

• PO:33:193 | Self-reported oropharyngeal dysphagia and swallowing-related quality of life in people with systemic sclerosis: preliminary results of a cross-sectional study Nikla Pacenti¹, Devis Benfaremo², Federica Lucia Galli², Andrea Colangelo³, Gianluca Moroncini² | ¹Internal Medicine Residency Program, Marche Polytechnic University Ancona, Italy; ²Department of Clinical and Molecular Sciences, Marche Polytechnic University Ancona, Italy; ³Medical student, Marche Polytechnic University Ancona, Italy

  Società Italiana di Reumatologia

  https://doi.org/10.4081/reumatismo.2025.2375

  12

• PO:33:194 | The role of anti-g protein-coupled receptors antibodies in the assessment of systemic sclerosis-primary heart involvement Beatrice Moccaldi¹, Giovanni Civieri², Annagrazia Cecere², Marco Binda¹, Marta Vadori², Laura Iop², Marta Tonello¹, Anna Cuberli¹, Andrea Benini¹, Emanuele Cozzi², Andrea Doria¹, Francesco Tona², Elisabetta Zanatta^1|2. | ¹Unità di Reumatologia, Dipartimento di Medicina ^DIMED, Università di Padova, Padova, Italy; ²Dipartimento di Scienze Cardio-Toraco-Vascolari e Sanità Pubblica, Università di Padova, Padova, Italy.

  Società Italiana di Reumatologia

  https://doi.org/10.4081/reumatismo.2025.2083

  153

• PO:33:195 | Evaluation of prevalence and role of anti-endothelin type a-receptor and anti-angiotensin ii type 1-receptor antibodies in a cohort of systemic sclerosis patients Clara Minerba¹, Sara Ferrigno¹, Antonella Grimaldi², Noemi Aprile³, Daniela Costanza², Laura Quarta², Maria Rita Ricciardi², Daniela Stasi³, Paola Conigliaro¹, Alberto Bergamini¹, Eugenio Quarta², Maria Sole Chimenti¹. | ¹U.O.C. Reumatologia, Dipartimento di Medicina dei Sistemi, Università di, Roma, Tor Vergata, Roma, Italy; ²U.O.S.D. Reumatologia, P.O. Vito Fazzi Lecce Italy; ³U.O.C. Patologia clinica e Microbiologia, P.O. Vito Fazzi Lecce Italy.

  Società Italiana di Reumatologia

  https://doi.org/10.4081/reumatismo.2025.2084

  128

• PO:33:197 | Systemic sclerosis and endothelial dysfunction: the passive leg movement technique in the assessment of no-mediated vascular impairment Silvia Guella¹, Giovanni Baldassarre³, Alessandro Gratton^2|3, Lucrezia Zuccarelli³, Elena Treppo², Emma Di Poi², Bruno Grassi³, Luca Quartuccio^2|3 | ¹SS Reumatologia-CMID Ospedale San Giovanni Bosco, Torino; ²Clinica di Reumatologia Ospedale Santa Maria della Misericordia, ASUFC, Udine; ³Dipartimento di Medicina, Università di Udine, Italy

  Società Italiana di Reumatologia

  https://doi.org/10.4081/reumatismo.2025.2207

  151

• PO:33:199 | Prevalence and clinical associations of antiphospholipid antibodies in patients with systemic sclerosis in the SPRING-SIR registry Antonio Tonutti^1|2, Ilaria Cavazzana³, Angela Ceribelli^1|2, Maria De Santis^1|2, Giacomo De Luca^4|5, Maria Grazia Lazzaroni³, Franco Franceschini³, Carlo Selmi^1|2, Valeria Riccieri⁶, Silvia Laura Bosello⁷, Fabio Cacciapaglia⁸, Veronica Codullo⁹, Francesca Ingegnoli¹⁰, Dilia Giuggioli¹¹, Rossella De Angelis¹², Clodoveo Ferri¹¹, Marco Matucci-Cerinic^4|5 | ¹Department of Biomedical Sciences, Humanitas Universityce Pieve Emanuele, Milan, Italy; ²Rheumatology and Clinical Immunology, IRCCS Humanitas Research Hospital Rozzano, Milan, Italy; ³Rheumatology and Clinical Immunology - ASST Spedali Civili Brescia - Department of Clinical and Experimental Sciences - Brescia, Italy; ⁴Vita-Salute San Raffaele University Milan, Italy; ⁵Unit of Immunology, Rheumatology, Allergy and Rare Diseases UnIRAR and INFLAGE Initiative, IRCCS San Raffaele Hospital Milan, Italy; ⁶University of Rome La Sapienza Rome, Italy; ⁷Catholic University of Sacred Heart Rome, Italy; ⁸LUM University Bari, Italy; ⁹Rheumatology Unit, Fondazione IRCCS Policlinico San Matteo Pavia, Italy; ¹⁰University of Milan Milan, Italy; ¹¹University of Modena and Reggio Emilia Modena, Italy; ¹²Politechnic University of Marche Ancona, Italy

  Società Italiana di Reumatologia

  https://doi.org/10.4081/reumatismo.2025.2376

  15

• PO:33:200 | Analysis of risk factors associated with vertebral fractures in systemic sclerosis: evidence from the "Sclero-RER" study group Alessandra Bezzi¹, Federica Lumetti², Martina Orlandi³, Fabio Mascella¹, Maria Cristina Focherini¹, Eugenio Arrigoni⁴, Elena Bravi⁴, Andrea Lo Monaco⁵, Amelia Spinella³, Ottavio Secchi³, Gianluigi Bajocchi⁶, Francesco Girelli⁷, Francesco Ursini⁸, Pierluigi Cataleta⁹, Massimo Reta¹⁰, Alarico Ariani^11|12, Dilia Giuggioli³ | ¹Internal Medicine and Rheumatology Unit, AUSL Romagna, Rimini ²AUSL of Modena and Rheumatology Unit, University Hospital Policlinico of Modena; ³Rheumatology Unit, University of Modena and Reggio Emilia; ⁴Rheumatology Unit, Guglielmo da Saliceto Hospital, Piacenza; ⁵Rheumatology, department of medical sciences, University of Ferrara; ⁶Rheumatology Unit, IRCCS Arcispedale Santa Maria Nuova Reggio Emilia; ⁷Rheumatology Unit, G.B. Morgagni - L. Pierantoni Hospital, Forlì; ⁸Rizzoli Orthopedic Institute, Rheumatology Unit, Department of Biomedical and Neuromotor Sciences, Alma Mater Studiorum Bologna; ⁹Hospital Santa Maria delle Croci, Rheumatology Unit, Department of Internal medicine, AUSL-Romagna Ravenna; ¹⁰Rheumatology Unit, AUSL of Bologna, Sant'Orsola Polyclinic Hospital, AOU IRCCS of Bologna; ¹¹Internal Medicine and Rheumatology Unit, University Hospital of Parma; ¹²AUSL Bologna and University of Bologna, IRCCS Policlinico Sant'Orsola, Bologna, Italy

  Società Italiana di Reumatologia

  https://doi.org/10.4081/reumatismo.2025.2208

  131

• PO:33:201 | Metabolic and functional state of circulating platelets in patients with systemic sclerosis Annalisa Villa¹, Simona Truglia¹, Francesca Maiorca², Annamaria Sabetta², Ludovica Lombardi², Silvia D'Orso², Lucia Stefanini², Fabrizio Conti¹, Marcella Visentini², Valeria Riccieri¹ | ¹Dipartimento di Scienze Cliniche, Internistiche, Anestesiologiche e Cardiovascolari, Università degli Studi di Roma La Sapienza; ²Dipartimento di Medicina Traslazionale e di Precisione, Università degli Studi di Roma La Sapienza

  Società Italiana di Reumatologia

  https://doi.org/10.4081/reumatismo.2025.2209

  132

• PO:33:202 | Assessment of Retinal Arteriolar Wall-to-Lumen Ratio and Renal Resistive Index in patients with Systemic Sclerosis Eleonora Pazzi^1|2, Elda Piovani^1|2, Claudia Barison^1|2, Liala Moschetti^1|2, Eleonora Pedretti^1|2, Mariagrazia Lazzaroni^1|2, Carolina De Ciuceis³, Claudia Agabiti-Rosei³, Giacomo Buso^3|4, Paolo Baggi³, Claudia Rossini³, Cristina Bevacqua³, Maria Lorenza Muiesan³, Ilaria Cavazzana¹, Franco Franceschini¹, Paolo Airò² | ¹Rheumatology and Clinical Immunology, ASST Spedali Civili of Brescia, University of Brescia, Brescia, Italy; ²Scleroderma Unit, ASST Spedali Civili of Brescia, Brescia, Italy; ³Department of Clinical and Experimental Sciences, Division of Internal Medicine, ASST Spedali Civili of Brescia, Univers Brescia, Italy; ⁴University of Lausanne, Lausanne Switzerland

  Società Italiana di Reumatologia

  https://doi.org/10.4081/reumatismo.2025.2377

  17

• PO:33:203 | Efficacy and safety of rituximab in eosinophilic fasciitis: report of three cases and systematic literature review Andrea Benini¹, Beatrice Moccaldi¹, Marco Binda¹, Anna Cuberli¹, Mariangela Favaro¹, Andrea Doria¹, Elisabetta Zanatta¹ | ¹UOC Reumatologia, Azienda Ospedale, Università di Padova, Italy

  Società Italiana di Reumatologia

  https://doi.org/10.4081/reumatismo.2025.2210

  175

• PO:34:204 | Impact of anti-centromere antibodies on immunosuppressive therapy persistence in systemic sclerosis: a single-center case-control study Martina Salerno¹, Marius Cadar¹, Ilaria Bisconti¹, Francesca Romana Di Ciommo¹, Elena Platania¹, Jacopo Landro¹, Beatrice De Girolamo¹, Davide Mohammad Reza Beigi^1|2, Simona Truglia¹, Fabrizio Conti¹, Valeria Riccieri¹ | ¹Rheumatology unit, AOU and Università di Cagliari; ²Asl Biella, Ospedale degli Infermi, Ponderano (BI), Italy

  Società Italiana di Reumatologia

  https://doi.org/10.4081/reumatismo.2025.2211

  147

• PO:34:205 | Optical coherence tomography angiography: a window on systemic sclerosis microangiopathy Martina Orlandi¹, Tommaso Verdina², Filippo Santoro¹, Alessandra Carobbio³, Amelia Spinella¹, Marco De Pinto¹, Giorgia Roveta¹, Dilia Giuggioli¹ | ¹Internal Medicine Residency Program, Marche Polytechnic University, Ancona; ²Department of Clinical and Molecular Sciences, Marche Polytechnic University, Ancona; ³Department of Interna, Ancona, Italy

  Società Italiana di Reumatologia

  https://doi.org/10.4081/reumatismo.2025.2212

  138

• PO:34:207 | When the Lungs Speak in Squeaks: Chronic Bird-Related HP in SSc-ILD with Incidental Lymphoma Mariagrazia Nuara¹, Marco De Pinto², Amelia Spinella², Stefania Cerri^1|2, Enrico Clini^1|2, Dilia Giuggioli^1|2 | ¹Università degli Studi di Modena e Reggio Emilia, Italy; ²AOU, Policlinico di Modena, Italy

  Società Italiana di Reumatologia

  https://doi.org/10.4081/reumatismo.2025.2378

  18

• PO:34:209 | Increased liver stiffness and fibrosis in systemic sclerosis: a single-center transient elastography cohort study. Nicola Ortalli^1|2, Simone Aldo Lari^1|2, Alessandra Vacca³, Erika Meleddu^1|2, Alberto Civolani⁴, Emanuela Vargiu⁴, Alberto Floris^1|2, Massimo Claudio Fantini⁴, Alberto Cauli^1|2. | ¹Rheumatology Unit, Azienda Ospedaliero Universitaria di Cagliari, Cagliari, Italy; ²Department of Medical Sciences and Public Health, University of Cagliari, Cagliari, Italy; ³Rheumatology Unit, Presidio Ospedaliero CTO di Iglesias Iglesias Italy; ⁴Gastroenterology Unit, Azienda Ospedaliero Universitaria di Cagliari, Cagliari, Italy.

  Società Italiana di Reumatologia

  https://doi.org/10.4081/reumatismo.2025.2085

  147

• PO:34:211 | Gynecological health and ultrasound evaluation among fertile women affected by Systemic sclerosis: an observational study Martina Orlandi¹, Sofia Gambigliani Zoccoli², Mariagrazia Nuara¹, Riccardo Cuoghi Costantini², Amelia Spinella¹, Marco De Pinto¹, Antonio La Marca², Dilia Giuggioli¹ | ¹Dipartimento di Scienze Mediche e Chirurgiche, Università di Modena e Reggio Emilia, Italy; ²Dipartimento Materno Infantile. Università di Modena e Reggio Emilia, Italy

  Società Italiana di Reumatologia

  https://doi.org/10.4081/reumatismo.2025.2379

  18

• PO:34:212 | Orofacial manifestations in systemic sclerosis: preliminary observational study and update of a single-center experience Amelia Spinella¹, Marco De Pinto¹, Giacomo Setti², Martina Orlandi^1|3, Samuele Veronesi², Federica Lumetti¹, Alessia Laneri¹, Luca Keller Sarmiento¹, Giorgia Roveta¹, Gilda Sandri^1|3, Pierantonio Bellini², Ugo Consolo², Dilia Giuggioli^1|3 | ¹Università degli Studi di Milano, Dipartimento di Scienze Cliniche e di Comunità, Milano; ²ASST G. Pini-CTO, UOC di Clinica Reumatologica, Milano; ³UOC di Reumatologia Clinica Pediatrica, ASST Gaetano Pini-CTO, Milano, Italy

  Società Italiana di Reumatologia

  https://doi.org/10.4081/reumatismo.2025.2213

  139

• PO:34:214 | Autonomic Symptoms Are Associated with Neuropathic Pain Features and Disease Impact in Systemic Sclerosis: Results From a Cross-Sectional Study Benedetta Bianchi¹, Francesca Francioso¹, Mariachiara Mangiafico¹, Fausto Salaffi¹, Rossella De Angelis¹, Marco Di Carlo¹ | ¹U.O. Reumatologia, Ospedale Carlo Urbani, Università Politecnica delle Marche Jesi, Italy

  Società Italiana di Reumatologia

  https://doi.org/10.4081/reumatismo.2025.2380

  18

• PO:34:217 | Possible role of phosphodiesterase type 5 inhibitors in the prevention of digital ulcers and videocapillaroscopic changes in patients with systemic sclerosis Elena Platania¹, Marius Cadar¹, Ilaria Bisconti¹, Davide Mohammad Reza Beigi^1|2, Francesca Romana Di Ciommo¹, Jacopo Landro¹, Martina Salerno¹, Beatrice De Girolamo¹, Simona Truglia¹, Fabrizio Conti¹, Valeria Riccieri¹ | ¹S.C. Reumatologia; ²S.C. Reumatologia

  Società Italiana di Reumatologia

  https://doi.org/10.4081/reumatismo.2025.2214

  168

• PO:35:218 | Switching the dose of mepolizumab in patients with Eosinophilic Granulomatosis with Polyangiitis (EGPA): a European retrospective multicentre real-world study Edoardo Biancalana¹, Irene Mattioli¹, Emanuele Chiara², Danilo Malandrino¹, Maria Canfora¹, Palmerini Miki¹, Maria Paola Lisi¹, Michela Gasparotto³, Paola Tomietto³, Maria Letizia Urban¹, Giacomo Bagni¹, Elena Silvestri¹, Alessandra Bettiol³, Augusto Vaglio³, Giacomo Emmi² | ¹Department of Experimental and Clinical Medicine, University of Florence Firenze, Italy; ²Department of Medical, Surgery and Health Sciences, University of Trieste Trieste, Italy; ³Clinical Medicine and Rheumatology Unit, Cattinara University Hospital, Trieste, Trieste, Italy; ⁴Department of Biomedical, Experimental and Clinical Sciences Mario Serio, University of Florence Firenze, Italy

  Società Italiana di Reumatologia

  https://doi.org/10.4081/reumatismo.2025.2381

  26

• PO:35:219 | Real-world effectiveness of mepolizumab on gastrointestinal involvement in eosinophilic granulomatosis with polyangiitis and hypereosinophilic syndrome: a multicentre retrospective study Alessia Gatti¹, Francesca Regola¹, Giulia Fontana¹, Mario Addrea Piga², Gianluca Moroncini², Palma Carlucci³, Angelo Vacca³, Paolo Delvino⁴, Enrico Heffler⁵, Emanuele Nappi⁵, Jakub Moll⁶, Laura Losappio⁶, Jan Schroeder⁶, Federica Davanzo⁷, Roberto Padoan⁷, Edoardo Conticini⁸, Paolo Cameli⁸, Greta Pacini⁹, Alvise Berti⁹, Lorenzo Vrola¹⁰, Paola Tomietto¹⁰, Luca Quartuccio¹¹, Jan Willem Cohen Tervaert¹², Sabrina Arnold¹³, Peter Lamprecht¹³, Florence Roufosse¹⁴, Ilaria Cavazzana¹, Franco Franceschini¹, Giacomo Emmi¹⁵, Paola Toniati¹. | ¹Rheumatology and Clinical Immunology Unit, ERN ReCONNET, ASST Spedali Civili of Brescia and University of Brescia, Italy, Brescia, Italy; ²Università Politecnica delle Marche and Azienda Ospedaliero Universitaria delle Marche, Ancona, Italy, Ancona, Italy; ³Section of Internal Medicine 'Guido Baccelli', DiMePRe-J, University of Bari 'Aldo Moro', Bari, Italy, Bari, Italy; ⁴Rheumatology Unit, IRCCS San Gerardo dei Tintori, Monza, Italy Monza Italy; ⁵Department of Biomedical Sciences, Humanitas University and Personalized Medicine, Asthma and Allergy IRCCS Humanitas, Milano, Italy; ⁶Division of Allergy and Clinical Immunology, ASST GOM Niguarda, Milan, Italy, Milano, Italy; ⁷Rheumatology Unit, Department of Medicine DIMED, University of Padua, Padova, Italy, Padova, Italy; ⁸University of Siena, Siena, Italy, Siena, Italy; ⁹Santa Chiara Hospital and University of Trento, Unit of Rheumatology, Trento, Italy Trento Italy; ¹⁰UCO Medicina Clinica, ASUGI, Cattinara Teaching Hospital, Trieste, Italy, Trieste, Italy; ¹¹Division of Rheumatology, Department of Medicine ^DMED, University of Udine, Udine, Italy, Udine, Italy; ¹²University of Alberta, Edmonton, Alberta, Canada and Maastricht University, Maastricht, The Netherlands Maastricht The Netherlands; ¹³Department of Rheumatology and Clinical Immunology, University of Lübeck, Lübeck, Germany Lubeck Germany; ¹⁴Department of Internal Medicine, Hôpital Universitaire de Bruxelles - Erasme, Université Libre de Bruxelles, Belgium Brussels Belgium; ¹⁵Clinical Medicine and Clinical Immunology and Rheumatology Unit Cattinara University Hospital and University of Trieste, Trieste, Italy.

  Società Italiana di Reumatologia

  https://doi.org/10.4081/reumatismo.2025.2086

  183

• PO:35:220 | IgG anti-pentraxin 3 autoantibodies distinguish eosinophilic granulomatosis with polyangiitis from severe eosinophilic asthma and chronic rhinosinusitis with nasal polyps Eleonora Fiorin¹, Anna Ghirardello¹, Federica Davanzo¹, Luca Iorio¹, Marta Codirenzi¹, Roberta Prevedello¹, Roberto Padoan¹, Andrea Doria¹. | ¹Università di Padova, Dipartimento di Medicina DIMED, UOC di Reumatologia, Padova, Italy.

  Società Italiana di Reumatologia

  https://doi.org/10.4081/reumatismo.2025.2087

  126

• PO:35:221 | Cryofibrinogen: a cold case. Characteristics and clinical outcomes from a cryofibrinogen positive cohort Daniele Catameró¹, Andrea Cito¹, Cristiana Colaprico¹, Teresa Caferri¹, Teresa Troiano¹, Anna Marinaccio¹, Marco Fornaro¹, Giuseppe Lopalco¹, Florenzo Iannone¹. | ¹Unit of Rheumatology , Department of Precision and Regenerative Medicine, Area Jonica DiMePRe-J, University of Bari, Bari, Italy.

  Società Italiana di Reumatologia

  https://doi.org/10.4081/reumatismo.2025.2088

  145

• PO:35:222 | Distinctive Features of Localized Vasculitis of the Gastrointestinal Tract Compared to Takayasu Arteritis: Insights from a Multicenter Cohort Study Vittorio Dibenedetto^1|2|3, Alessandro Tomelleri^1|2, Corrado Campochiaro^1|2, Elena Baldissera^1|2, Luca Moroni^1|2, Padoan Roberto⁴, Marco Matucci-Cerinic^1|2|3, Lorenzo Dagna^1|2|3 | ¹Unit of Immunology, Rheumatology, Allergy and Rare Diseases UNIRAR, IRCCS San Raffaele Hospital Milan, Italy; ²Inflammation, Fibrosis and Ageing Intitiative INFLAGE, IRCCS San Raffaele Hospital Milan, Italy; ³Vita-Salute San Raffaele University, Milan, Italy Milan, Italy; ⁴University Hospital of Padova, Department of Internal Medicine and Rheumatology Padova, Italy

  Società Italiana di Reumatologia

  https://doi.org/10.4081/reumatismo.2025.2382

  14

• PO:35:223 | Biologic therapy for sustained remission in eosinophilic myocarditis: real-world evidence from a tertiary center experience Federica Davanzo¹, Caterina Menghi², Andrea Silvio Giordani², Anna Baritussio², Federico Scognamiglio², Cristina Vicenzetto², Luca Iorio¹, Renzo Marcolongo², Cristina Basso³, Andrea Doria¹, Roberto Padoan¹, Alida Linda Patr Caforio² | ¹Rheumatology Unit, Department of Medicine, University of Padua Padova, Italy; ²Cardiology Unit, Department of Cardiac, Vascular, Thoracic Sciences and Public Health, University of Padua Padova, Italy; ³Cardiovascular Pathology, Department of Cardiac, Thoracic and Vascular Sciences and Public Health, University of Padua Padova, Italy

  Società Italiana di Reumatologia

  https://doi.org/10.4081/reumatismo.2025.2383

  23

• PO:35:224 | Capturing What BVAS Misses: Patient-Reported Outcomes Reflect Disease Activity and Burden in EGPA Marta Codirenzi¹, Federica Davanzo¹, Luca Iorio¹, Eleonora Fiorin¹, Roberta Prevedello¹, Roberto Padoan¹, Andrea Doria¹ | ¹Unità di reumatologia, dipartimento di medicina DIMED,Università degli studi di Padova, Italy

  Società Italiana di Reumatologia

  https://doi.org/10.4081/reumatismo.2025.2384

  14

• PO:35:226 | Red flags raising suspicion of Eosinophilic Granulomatosis with Polyangiitis (EGPA): results from the European EGPAware Delphi study Gabriele Brembilla¹, Bernhard Hellmich^2|3, Apostolos Bossios^4|5, Chistian Domingo-Ribas^6|7, Giacomo Emmi⁸, Cristina Ponte^9|10, Maria Roser Solans-Laque¹¹, Íñigo Jesus Rúa-Figueroa¹², Augusto Vaglio¹³, Dimitrios Vassilopoulos¹⁴, Konstantina Kallinikou¹⁵, Benjamin Terrier¹⁶ | ¹GSK Verona, Italy; ²Medius Klinik Kirchheim Kirchheim unter Teck Germany; ³Teaching Hospital of the University of Tübingen Tübingen Germany; ⁴Karolinska University Hospital Stockholm, Sweden; ⁵Karolinska Institutet Solna, Sweden; ⁶Parc Taulí University Hospital. Parc Taulí Research and Innovation Institute I3PT-CERCA Barcelona Spain; ⁷Department of Medicine, Universitat Autònoma de Barcelona ^UAB Barcelona Spain; ⁸University of Trieste, UNITS, Trieste, Italy; ⁹Santa Maria Hospital Lisbon, Portugal; ¹⁰Lisbon Academic Medical Center Lisbon, Portugal; ¹¹Vall d'Hebron University Hospital Barcelona Spain; ¹²Gran Canaria Doctor Negrín Hospital Las Palmas de Gran Canaria Spain; ¹³University of Florence Florence, Italy; ¹⁴National and Kapodistrian University of Athens School of Medicine Athens, Greece; ¹⁵GSK Athens, Greece; ¹⁶Cochin Hospital Paris, France

  Società Italiana di Reumatologia

  https://doi.org/10.4081/reumatismo.2025.2385

  29

• PO:35:227 | Long-term renal and survival outcomes in microscopic polyangiitis: data from an observational monocentric cohort Roberta Prevedello¹, Federica Davanzo¹, Luca Iorio¹, Eleonora Fiorin¹, Marta Codirenzi¹, Roberto Padoan¹, Andrea Doria¹. | ¹Unità di Reumatologia, Dipartimento di Medicina DIMED, Università degli Studi di Padova, Padova, Italy.

  Società Italiana di Reumatologia

  https://doi.org/10.4081/reumatismo.2025.2089

  138

• PO:35:228 | Polymyalgia rheumatica and giant cell arteritis induced by immune checkpoint inhibitors for cancer treatment: a systematic review and meta-analysis highlighting differences from the idiopathic forms Elvis Hysa¹, Andrea Casabella², Emanuele Gotelli¹, Rosanna Campitiello¹, Carlo Genova³, Enrica Teresa Tanda⁴, Carmen Pizzorni¹, Alberto Sulli¹, Vanessa Smith⁵, Marco Amedeo Cimmino⁶, Sabrina Paolino¹, Maurizio Cutolo¹. | ¹Laboratory of Experimental Rheumatology and Academic Division of Clinical Rheumatology, Department of Internal Medicine, Genova, Italy; ²IRCCS Ospedale Policlinico San Martino, Genova, Italy; ³Academic Oncology Unit; IRCCS Ospedale Policlinico San Martino, Genova, Italy; ⁴UOC Medical Oncology Clinic 2, Department of Internal Medicine, University of Genova, Genova, Italy; ⁵Department of Internal Medicine, Ghent University, Department of Rheumatology, Ghent University Hospital, Ghent, Belgium; ⁶Rheumatology Outpatient Clinic, Villa Ravenna Chiavari Italy.

  Società Italiana di Reumatologia

  https://doi.org/10.4081/reumatismo.2025.2090

  143

• PO:35:233 | Tocilizumab is associated with improved relapse-free survival in polymyalgia rheumatica: a multicentre retrospective study Milena Bond¹, Giovanni Adami², Marianna Tamussin³, Mario Frasca⁴, Sara Zandonella Callegher¹, Marcello Govoni³, Maurizio Rossini², Lorenzo Dagna⁴, Marco Matucci Cerinic⁴, Christian Dejaco¹, Alessandro Tomelleri⁴ | ¹Department of Rheumatology, Brunico Hospital ASAA-SABES, Teaching Hospital of the Paracelsius Medical University Bunico, Italy; ²Rheumatology Unit, University of Verona, Policlinico Borgo Roma Verona, Italy; ³Rheumatology Unit, Department of Medical Sciences, University of Ferrara and Azienda Ospedaliero-Universitaria S. Anna Ferrara, Italy; ⁴Unit of Immunology, Rheumatology, Allergy and Rare Diseases, IRCCS San Raffaele Hospital Milano, Italy

  Società Italiana di Reumatologia

  https://doi.org/10.4081/reumatismo.2025.2386

  19

• PO:35:234 | Sustained Vasculitis Quiescence and CS Reduction with Mepolizumab 100 mg Francesca Mascia¹, Angelo Fassio², Marco Zurlo¹, Davide Chesini³, Francesco Pollastri², Giovanni Adami², Davide Gatti⁴, Maurizio Rossini⁴, Matteo Maule⁵, Gianentrico Senna¹, Marco Caminati¹ | ¹University of Verona - Allergology and Clinical Immunology Verona, Italy; ²Policlinico G. B. Rossi - Rheumatology Verona, Italy; ³University of Verona - Faculty of Medicine and Surgery Verona, Italy; ⁴University of Verona - Rheumatology Verona, Italy; ⁵Policlinico G. B. Rossi - Allergology and Clinical Immunology Verona, Italy

  Società Italiana di Reumatologia

  https://doi.org/10.4081/reumatismo.2025.2387

  18

• PO:36:238 | Clinical, functional, and radiological similarities between interstitial lung disease–anti–myeloperoxidase and idiopathic pulmonary fibrosis Enrico Colombo¹, Jessica Gozzi², Paolo Francia³, Giulia Cervi², Marilena Frigato¹, Martina Garuti², Francesca Bartoli¹, Irene Gavioli¹, Caterina Cerbone², Massimiliano Beccaria², Maria Teresa Costantino¹ | ¹SC Allergologia, Immunologia Clinica e Reumatologia, ASST Mantova; ²SC Pneumologia, ASST Mantova; ³SC Radiologia, ASST Mantova, Italy

  Società Italiana di Reumatologia

  https://doi.org/10.4081/reumatismo.2025.2215

  146

• PO:36:242 | Bilateral central retinal artery occlusion as the first manifestation of eosinophilic granulomatosis with polyangiitis during benralizumab therapy Benedetta Fazzi¹, Elena Treppo¹, Lucia Finocchio², Maria Pillon¹, Luca Quartuccio¹ | ¹Clinica di Reumatologia, Dipartimento di Medicina, Presidio Ospedaliero Universitario Santa Maria della Misericordia, Udine; ²SOC Oculistica, Presidio Ospedaliero Universitario Santa Maria della Misericordia, ASUFC, Udine, Italy

  Società Italiana di Reumatologia

  https://doi.org/10.4081/reumatismo.2025.2216

  145

• PO:36:243 | Drug survival, discontinuation reasons and disease activity in patients with Behçet's disease treated with infliximab - a real-life study Antonello Sulis¹, Federica Di Cianni¹, Maria Laura Manca², Rosaria Talarico¹, Marta Mosca¹. | ¹Rheumatology Unit of Pisa, University of Pisa, Pisa, Italy, Pisa, Italy; ²Department of Clinical and Experimental Medicine and Department of Mathematics, University of Pisa, Italy, Pisa, Italy.

  Società Italiana di Reumatologia

  https://doi.org/10.4081/reumatismo.2025.2091

  150

• PO:36:244 | Early diagnosis in eosinophilic granulomatosis with polyangiitis: a multidisciplinary approach Federico Giuseppe Lazzaro¹, Elena Chiaradia², Chiara Lombardi², Flavia Leone¹, Massimo Nucci², Roberta Masnata², Flora Niedda², Maria Rita Gigante¹, Pietro Rubortone¹, Silvia Laura Bosello^1|2, Maria Antonietta D'Agostino^1|2, Augusta Ortolan^1|2. | ¹Divisione di Reumatologia ed Immunologia Clinica, Fondazione Policlinico Universitario A. Gemelli IRCCS, Roma, Italy; ²Università Cattolica del Sacro Cuore, Roma, Italy.

  Società Italiana di Reumatologia

  https://doi.org/10.4081/reumatismo.2025.2092

  133

• PO:36:245 | Uncovering clinical and demographic differences in major organ involvement versus benign Behçet’s disease: insights from a single-centre study Federica Di Cianni¹, Antonello Sulis¹, Maria Laura Manca², Rosaria Talarico¹, Marta Mosca¹. | ¹Rheumatology Unit, University of Pisa, Pisa, Italy; ²Department of Clinical and Experimental Medicine and Department of Mathematics, University of Pisa, Pisa, Italy.

  Società Italiana di Reumatologia

  https://doi.org/10.4081/reumatismo.2025.2093

  147

• PO:36:246 | Early real-world outcomes with benralizumab in eosinophilic granulomatosis with polyangiitis: a monocentric retrospective Richard Borrelli¹, Stefania Nicola¹, Federica Corradi¹, Iuliana Badiu¹, Marzia Boem¹, Valentina Marmora¹, Simone Negrini¹, Luisa Brussino¹. | ¹SCDU Immunologia e Allergologia, AO Mauriziano, Dipartimento di Scienze Mediche, Università degli Studi di Torino, Torino, Italy.

  Società Italiana di Reumatologia

  https://doi.org/10.4081/reumatismo.2025.2094

  141

• PO:36:250 | Eosinophilic granulomatosis with polyangiitis associated to Alpha-1 Antitrypsin Deficiency: a land still unexplored Maria Grazia Malandra¹, Vacchi Caterina¹, Santoro Filippo¹, Cassone Giulia¹, Martina Orlandi¹, Stefania Cerri¹, Dilia Giuggioli¹ | ¹Università di Modena - Reggio Emilia, S.C. Reumatologia Azienda Ospedaliera Universitaria Policlinico di Modena Modena, Italy; ²S.C. Reumatologia Azienda Ospedaliera Universitaria Policlinico di Modena Modena, Italy; ³Università di Modena e Reggio Emilia, S.C. Reumatologia Azienda Ospedaliera Universitaria Policlinico di Modena Modena, Italy; ⁴S.C. Reumatologia Azienda Ospedaliera Universitaria Policlinico di Modena Modena, Italy; ⁵Università di Modena e Reggio Emilia, S.C. Reumatologia Azienda Ospedaliera Universitaria Policlinico di Modena Modena, Italy; ⁶Università di Modena e Reggio Emilia, S.C. Reumatologia Azienda Ospedaliera Universitaria Policlinico di Modena Modena, Italy; ⁷Università di Modena e Reggio Emilia, S.C. Reumatologia Azienda Ospedaliera Universitaria Policlinico di Modena Modena, Italy

  Società Italiana di Reumatologia

  https://doi.org/10.4081/reumatismo.2025.2388

  14

• PO:36:251 | Rheumatoid factor predicts vasculitis relapse in eosinophilic granulomatosis with polyangiitis: a machine learning approach Luca Iorio¹, Federica Davanzo¹, Giulia Lorenzoni², Eleonora Fiorin¹, Marta Codirenzi¹, Roberta Prevedello¹, Debora Campaniello¹, Dario Gregori², Roberto Padoan¹, Andrea Doria¹. | ¹Rheumatology Unit, DIMED, University of Padova, Padova, Italy; ²Unit of Biostatistics, Epidemiology and Public Health, DCTV, University of Padova, Padova, Italy.

  Società Italiana di Reumatologia

  https://doi.org/10.4081/reumatismo.2025.2095

  160

• PO:36:252 | Long-Term Outcomes of Patients with Takayasu Arteritis in the Era of Biological Agents: a Multicenter International Study Alessandro Tomelleri¹, Durga Prasanna Misra², Fatma Alibaz-Oner³, Chiara Marvisi⁴, Chiara Calabrese¹, Upendra Rathore², Aysegul Avcu³, Adele Del Giudice⁴, Elisabetta Olivi⁴, Caterina Ricordi⁴, Corrado Campochiaro¹, Elena Baldissera¹, Marco Matucci-Cerinic¹, Haner Direskeneli³, Carlo Salvarani⁴, Lorenzo Dagna¹ | ¹IRCCS Ospedale San Raffaele, Unità di Immunologia, Reumatologia, Allergologia e Malattie Rare Milano, Italy; ²Sanjay Gandhi Postgraduate Institute of Medical Sciences SGPGIMS, Clinical Immunology and Rheumatology Lucknow Country, India; ³Marmara University, School of Medicine, Department of Internal Medicine, Division of Rheumatology Istanbul, Turkey; ⁴Azienda USL-IRCCS di Reggio Emilia, Unità di Reumatologia Reggio Emilia, Italy

  Società Italiana di Reumatologia

  https://doi.org/10.4081/reumatismo.2025.2389

  24

• PO:36:253 | Lifestyle and Behçet's syndrome: a preliminary study on gender differences Pietro Leccese¹, Angela Anna Padula¹, Nancy Lascaro¹, Salvatore D'Angelo¹, Maria Carmela Padula¹ | ¹UOC Reumatologia AOR San Carlo, Potenza, Italy

  Società Italiana di Reumatologia

  https://doi.org/10.4081/reumatismo.2025.2217

  160

• PO:37:254 | Absence of ciliary artery occlusion does not exclude arteritic anterior ischemic optic neuropathy (A-AION): diagnostic and pathophysiologic implications Ruggiero Mascolo Mascolo¹, Stefano Erba², Alba Xhepa², Martina Martelli¹, Gabriella Marinaro¹, Giulia Dieguez¹, Giacomo Iacomelli¹, Chiara Facoetti¹, Michel Chevallard³, Bruno Lucchino³, Mariaeva Romano³, Andrea Locatelli³, Giuliana La Paglia³, Donatella Ventura³, Giovanna Randisi³, Alessandra Mutti³, Alessandro Invernizzi², Stefano De Angelis², Giovanni Staurenghi², Antonio Brucato⁴, Enrico Tombetti⁴ | ¹Dipartimento di Medicina Interna, ASST Fatebenefratelli-Sacco, Università degli studi di Milano, Italy; ²U.O. Oculistica, ASST Fatebenefratelli-Sacco Milano, Italy; ³U.O. Reumatologia, ASST Fatebenefratelli-Sacco Milano, Italy; ⁴Dipartimento di Scienze cliniche e biomediche, ASST Fatebenefratelli-Sacco, Università degli studi di Milano, Italy

  Società Italiana di Reumatologia

  https://doi.org/10.4081/reumatismo.2025.2390

  18

• PO:37:256 | Spontaneous renal artery dissection: a subtle presentation of a “vasculitis-mimicker” Federdo Nogarin¹, Alfonso Valerio Massara¹, Zairo Ferrante², Filippo Furicchia³, Riccardo Bertola¹, Elena Pollicelli¹, Ilaria Calciolari¹, Sopie Secka¹, Andrea Lo Monaco¹, Marcello Govoni¹ | ¹UOC Reumatologia; ²UOC Radiologia Ospedaliera; ³UOC Radiologia Vascolare e Interventistica, Arcispedale Sant'Anna, Ferrara, Italy

  Società Italiana di Reumatologia

  https://doi.org/10.4081/reumatismo.2025.2218

  152

• PO:37:257 | Giant cell arteritis debuting with aortic involvement: the importance of integrated diagnostics in fever of unknown origin Alessandro Gratton¹, Giovanni Striani¹, Luisa Occhipinti¹, Stefania Sacco¹, Enrico Pegolo², Luca Quartuccio¹ | ¹Rheumatology Clinic and ² Institute of Anatomical Pathology, Department of Laboratory Medicine, University of Udine, Hospital “Santa Maria della Misericordia”, Udine, Italy

  Società Italiana di Reumatologia

  https://doi.org/10.4081/reumatismo.2025.2219

  128

• PO:37:258 | Neutrophil and eosinophil extracellular traps in eosinophilic granulomatosis with polyangiitis: phenotype-based characterization and response to mepolizumab Michele Moretti¹, Francesco Ferro², Francesco Pisani¹, Elisa Ferrigno¹, Gaetano La Rocca¹, Federica Di Cianni³, Rosaria Talarico², Marta Mosca¹, Chiara Baldini¹, Ilaria Puxeddu¹. | ¹University of Pisa - Department of Clinical and Experimental Medicine, Pisa, Italy; ²Azienda Ospedaliero Universitaria Pisana - Rheumatology Unit, Pisa, Italy; ³University of Siena, Siena, Italy.

  Società Italiana di Reumatologia

  https://doi.org/10.4081/reumatismo.2025.2096

  138

• PO:37:259 | Is there a seasonal pattern in giant cell arteritis? Revisiting the evidence in a large monocentric cohort of 1203 patients Milena Bond¹, Philipp Bosch², Aaron Juche³, Hans Bastian³, Wolfgang Schmidt⁴. | ¹Department of Rheumatology, Hospital of Bruneck ASAA-SABES, Teaching Hospital of the Paracelsius Medical University Brunico Italy; ²Department of Rheumatology and Immunology, Medical University of Graz, Graz, Austria; ³Medical Centre for Rheumatology Berlin-Buch, Immanuel Krankenhaus Berlin Berlin Germany; ⁴Waldfriede Hospital, Rheumatology, Berlin, Germany.

  Società Italiana di Reumatologia

  https://doi.org/10.4081/reumatismo.2025.2097

  137

• PO:37:260 | Mepolizumab in the treatment of patients with eosinophilic granulomatosis with polyangiitis: real-life experience from a single-center cohort Eleonora Bruschi¹, Fabrizio Angeli¹, Alessandro Belotti Masserini¹, Stefania Bertocchi¹, Silvia Breda¹, Elide Lupi¹, Valeria Rossi¹, Tania Ubiali¹, Massimiliano Limonta¹ | ¹ASST Papa Giovanni XXIII Bergamo Italy

  Società Italiana di Reumatologia

  https://doi.org/10.4081/reumatismo.2025.2220

  147

• PO:37:263 | First non invasive visualization of vasculitis in the retinal arteries by high resolution optical coherence tomography in a patient with giant cell arteritis Ruggiero Mascolo¹, Chiara Facoetti¹, Claudia Nardi², Stefano Erba², Martina Martelli¹, Gabriella Marinaro¹, Giulia Dieguez¹, Giacomo Iacomelli¹, Chiara Carollo¹, Michel Chevallard³, Bruno Lucchino³, Mariaeva Romano³, Andrea Locatelli³, Donatella Ventura³, Giovanna Randisi³, Giuliana La Paglia³, Alessandra Mutti³, Alessandro Invernizzi², Stefano De Angelis², Giovanni Staurenghi², Antonio Brucato⁴, Enrico Tombetti⁴. | ¹Dipartimento di Medicina Interna, ASST Fatebenefratelli-Sacco, Università degli studi di Milano, Milano, Italy; ²U.O. Oftalmologia, ASST Fatebenefratelli-Sacco, Università degli studi di Milano, Milano, Italy; ³U.O. Reumatologia, ASST Fatebenefratelli-Sacco, Università degli studi di Milano, Milano, Italy; ⁴Dipartimento di scienze cliniche e biomediche, ASST Fatebenefratelli-Sacco, Università degli studi di Milano, Milano, Italy.

  Società Italiana di Reumatologia

  https://doi.org/10.4081/reumatismo.2025.2098

  178

• PO:37:266 | Long-term manifestation of graft-versus-host disease presenting as a vasculitic-like syndrome: a rare case report Camilla Mazzanti¹, Gianluca Santoboni¹, Claudio Angrisani¹, Massimiliano De Simone¹, Giuliana Marciani¹, Alessandra Fiorentini¹ | ¹Ospedale Santa Rosa Viterbo, Italy

  Società Italiana di Reumatologia

  https://doi.org/10.4081/reumatismo.2025.2391

  20

• PO:37:267 | Mimickers of polyarteritis nodosa: a case of segmental arteriolar mediolysis Filippo Santoro¹, Caterina Vacchi², Giulia Cassone², Maria Grazia Malandra¹, Dilia Giuggioli^1|2 | ¹UOSD Reumatologia, Ospedale San Camillo De Lellis, Rieti; ²UOC Igiene e Sanità Pubblica, ASL Rieti; ³Direzione Sanitaria, ASL Rieti, Italy

  Società Italiana di Reumatologia

  https://doi.org/10.4081/reumatismo.2025.2221

  167

• PO:37:268 | Antineutrophil cytoplasmic antibodies-associated vasculitis mimicking giant cell arteritis: a diagnostic dilemma Bruno Biasi¹, Elena Vanni¹, Marco De Pinto², Giulia Cassone², Dilia Giuggioli^1|2. | ¹Rheumatology Unit, School of Medicine, University of Modena and Reggio Emilia, Modena, Modena, Italy; ²Rheumatology Unit, Azienda Ospedaliera-Universitaria Policlinico di Modena, Modena, Italy, Modena, Italy.

  Società Italiana di Reumatologia

  https://doi.org/10.4081/reumatismo.2025.2099

  139

• PO:37:269 | Intensive therapeutic plasma exchange in life-threatening ANCA-associated vasculitis Davide Bertelle, Riccardo Bixio, Francesco Pollastri, Maurizio Rossini, Angelo Fassio, Alessandro Giollo | Unità di Reumatologia, Dipartimento di Medicina Clinica e Sperimentale, Università di Pisa

  Società Italiana di Reumatologia

  https://doi.org/10.4081/reumatismo.2025.2222

  147

• PO:37:270 | Efficacy of iloprost as a therapy for skin ulcers in cryofibrinogenemia and cryoglobulinemia: a complex case in a fragile patient Luca Keller Sarmiento¹, Amelia Spinella², Marco De Pinto², Giorgia Roveta¹, Dilia Giuggioli^1|2. | ¹Università degli Studi di Modena e Reggio Emilia, Modena, Italy; ²Unità di Reumatologia del Policlinico di Modena, Modena, Italy.

  Società Italiana di Reumatologia

  https://doi.org/10.4081/reumatismo.2025.2100

  141

• PO:38:278 | Cognitive behavioural therapy vs. physical therapy for chronic primary low back pain: a systematic review with meta-analysis of randomised controlled trials Luca Castioni¹, Stefano Salvioli² | ¹Università degli studi di Ferrara; ²Scuola di fisioterapia Claudiana, Bolzano, Italy

  Società Italiana di Reumatologia

  https://doi.org/10.4081/reumatismo.2025.2223

  151

• PO:38:280 | Accuracy of generative artificial intelligence in risk of bias assessment using RoB 2.0 tool and extracting data in exercise therapy for chronic low back pain randomised controlled trials Luca Carrer¹, Marco Pozzati², Dario Taborelli¹, Niccolò Maschi¹, Tiziano Innocenti^1|3, Stefano Salvioli¹ | ¹DINOGMI, Università di Genova, Savona; ²Dipartimento di Neuroscienze e Riabilitazione, Università di Ferrara; ³GIMBE Foundation, Bologna, Italy

  Società Italiana di Reumatologia

  https://doi.org/10.4081/reumatismo.2025.2224

  144

• PO:38:281 | Therapeutic exercise in temporomandibular disorders: a scoping review of the literature Federico Amateis¹, Gabriele Aimini¹, Paolo Mastromarchi¹, Lorenzo Lo Russo¹, Marco Chiodini¹, Roberta Giova Bazzacchi¹, Noemi Corbetta¹, Stefano Salvioli¹.   | <i> ¹Department of Neurosciences, Rehabilitation, Opthalmology, Genetics, Maternal and Child Health, University of Genoa Italy; ³Scuola Universitaria per la Svizzera Italiana, DEASS Manno Switzerland; ⁶Department of Maxillo-Facial Surgery, Santi Paolo e Carlo Hospital, University of Milan Italy; ⁷Department of Neurosciences, Rehabilitation, Opthalmology , Genetics, Maternal and Child Health, University of Genoa Italy; ⁸Department of Neurosciences, Rehabilitation, Opthalmology , Genetics, Maternal and Child Health, University of Genoa Italy. </i>

  Società Italiana di Reumatologia

  https://doi.org/10.4081/reumatismo.2025.2225

  141

• PO:38:283 | Accuracy of chatgpt 4 omni in providing clinical recommendations in musculoskeletal care: a valuable support for clinicians and patients? Dario Taborelli¹, Silvia Negro¹, Federico Padovani², Tiziano Innocenti^1|3, Stefano Salvioli¹ | ¹DINOGMI, Università di Genova, Savona; ²Dipartimento di Neuroscienze e Riabilitazione, Università di Ferrara; ³GIMBE Foundation, Bologna, Italy

  Società Italiana di Reumatologia

  https://doi.org/10.4081/reumatismo.2025.2226

  139

• PO:38:285 | Cross-sectional analysis: interpretation of nonstatistically significant results in randomised controlled clinical trials in rehabilitation Caterina Mugnai¹, Luca Falsiroli Maistrello^2|3|4, Giacomo Fiacca³, Michele Perrucchini³, Noemi Corbetta³, Federico Amateis³, Stefano Salvioli³ | ¹University of Ferrara; ²ULSS 9 Scaligera, Department of Physical Medicine and Rehabilitation, G. Fracastoro Hospital, San Bonifacio ^VR; ³Department of Neurosciences, Rehabilitation, Ophthalmology, Genetics, Maternal and Child Health, University of Genoa; ⁴School of Physiotherapy, Department of Neuroscience, Biomedicine and Movement, University of Verona, Italy

  Società Italiana di Reumatologia

  https://doi.org/10.4081/reumatismo.2025.2227

  121

• S02:5 | Combined anti-IL-5/IL-5r and dupilumab therapy in eosinophilic granulomatosis with polyangiitis: a European retrospective study Miriam Guerini¹, Pavel Novikov², Roberto Padoan³, Georgina Espigol Frigolé⁴, Jan Willem Cohen Tervaert⁵, Vincent Grobost⁶, Laurent Guilleminault⁷, Jan Walter Schroeder⁸, Bernhard Hellmich⁹, Joana Martins Martinho¹⁰, Camillo Ribi¹¹, Matthieu Groh¹², Benjamin Terrier¹³. | ¹IRCCS Policlinico S. Matteo, University of Pavia, Pavia, Italy; ²Sechenov University, Moscow, Russia; ³University of Padova, Padova, Italy; ⁴Hospital Clinic, University of Barcelona, Barcelona, Spain; ⁵University of Alberta, Edmonton, Canada; ⁶CHU Estaing Clermont-Ferrand France; ⁷Toulouse University Toulouse France; ⁸ASST Grande Ospedale Metropolitano Niguarda, Milano, Italy; ⁹Medius Kliniken Kirchheim-Teck Germany; ¹⁰ULS Santa Maria, Lisbon, Portugal; ¹¹Centre Hospitalier Universitaire Vaudois, Lausanne, Switzerland; ¹²Hopital Foch, Suresnes, France; ¹³Service de Medecine interne, Hopital Cochin, AP-HP, Paris, France.

  Società Italiana di Reumatologia

  https://doi.org/10.4081/reumatismo.2025.2101

  186

• S02:6 | Monocyte-Driven Inflammation and Inflammasome Activation in ANCA-Positive EGPA: Evidence of Persistent Immune Activation During Remission Chiara Baggio¹, Luca Iorio¹, Carlotta Boscaro^2|3, Federica Davanzo¹, Marta Tonello¹, Mattia Albiero⁴, Andrea Doria¹, Paolo Sfriso¹, Roberto Padoan¹, Francesca Oliviero¹ | ¹Rheumatology Unit, Department of Medicine, University of Padova, Italy; ²Department of Medicine, University of Padova, Italy; ³Veneto Institute of Molecular Medicine, Laboratory of Experimental Diabetology, Italy; ⁴Department of Surgery, Oncology, and Gastroenterology, University of Padova, Italy

  Società Italiana di Reumatologia

  https://doi.org/10.4081/reumatismo.2025.2392

  19

• S05:5 | Romosozumab in Post-Menopausal Women with Multiple Myeloma, a Prospective 12-Month Study Giovanni Adami¹, Mariana Diz Lopes¹, Camilla Benini¹, Davide Gatti¹, Ombretta Viapana¹, Elena Marchetti², Martina Tinelli², Maurizio Rossini¹ | ¹UOC Reumatologia, Università degli Studi di Verona Verona, Italy; ²UOC Ematologia, Università degli Studi di Verona Verona, Italy

  Società Italiana di Reumatologia

  https://doi.org/10.4081/reumatismo.2025.2393

  18

• S05:6 | Prevalence of osteoporosis and bone mineral metabolism disorders in an Italian cohort of patients with microcrystalline arthritis: results from the PREMIA observational study of the Italian Society of Rheumatology Silvia Grignaschi¹, Sonia Farah², Silvia Balduzzi¹, Bernd Raffeiner³, Carlomaurizio Montecucco⁴, Fausto Salaffi², Enrico Selvi⁵, Annamaria Iagnocco⁶, Fabiola Atzeni⁷, Serena Guiducci⁸, Rosario Foti⁹, Maria Manara¹⁰, Marcello Govoni¹¹, Carlo Selmi¹², Francesca Oliviero¹³, Roberta Ramonda¹³ | ¹ASST Pavia; ²Ospedale Carlo Urbani Jesi Italy; ³Azienda Sanitaria dell'Alto Adige, Bolzano; ⁴IRCCS Fondazione Policlinico San Matte, Pavia; ⁵AOU Senese, Siena; ⁶Ospedale MAuriziano, Torino; ⁷Università di Messina; ⁸AOU Careggi, Firenze; ⁹AOU Policlinico G. Rodolico, Catania; ¹⁰ASST Gaetano Pini-CTO Milano; ¹¹AUSL Ferrara; ¹²Humanitas San Pio X, Milano; ¹³AOU Padova, Italy

  Società Italiana di Reumatologia

  https://doi.org/10.4081/reumatismo.2025.2228

  139

• S07:5 | Ankle ultrasound patterns may in the identification of Löfgren’s syndrome in patients with acute-onset erythema nodosum Davide Corradini¹, Alberto Floris¹, Andrea Carta², Mattia Congia¹, Elisabetta Chessa¹, Matteo Piga¹, Alberto Cauli¹. | ¹Rheumatology Unit, AOU and University of Cagliari, Cagliari, Italy; ²Department Economics and Business, University of Cagliari, Cagliari, Italy.

  Società Italiana di Reumatologia

  https://doi.org/10.4081/reumatismo.2025.2102

  150

• S13:5 | Association between vasoactive-vasodilating therapy and reduced detection of pulmonary arterial hypertension in systemic sclerosis: evidence from a European Scleroderma Trials and Research study Nicola Farina¹, Silvia Bellando-Randone¹, Sebastien Sanges², Hilde Jenssen Bjørkekjær³, Lorenzo Tofani⁴, Marie-Elise Truchetet⁵, Vanessa Smith⁶, Andra Balanescu⁷, Christina Bergmann⁸, Yannick Allanore⁹, Philipp Klemm¹⁰, Simona Truglia¹¹, Luca Idolazzi¹², Christopher Denton¹³, Roberta Foti¹⁴, Anna Wojteczek¹⁵, Emmanuel Chatelus¹⁶, Madelon Vonk¹⁷, Serena Guiducci¹, David Launay², Eric Hachulla², Jeska De Vries-Bouwstra¹⁸, Anna-Maria Hoffmann-Vold¹⁹, Oliver Distler²⁰, Marco Matucci-Cerinic¹, Cosimo Bruni¹. | ¹Department of Experimental and Clinical Medicine, Scleroderma Unit, Division of Rheumatology, University of Florence, Az, Firenze, Italy; ²Univ. Lille, Inserm, CHU Lille, Department of Internal Medicine and Clinical Immunology, Reference Center for Rare Autoi, Lille, France; ³Department of Rheumatology, Hospital of Southern Norway, Kristiansand, Norway; ⁴Department of Statistics, Informatics and Applications, University of Florence, Firenze, Italy; ⁵Rheumatology department, CHU de Bordeaux, Bordeaux, France; ⁶University of Ghent, Department of Rheumatology, Gent, Belgium; ⁷Department of Rheumatology, St. Maria Hospital, Carol Davila, University of Medicine and Pharmacy Bucharest Romania; ⁸Department Internal Medicine 3, University Hospital Erlangen, Erlangen, Germany; ⁹Rheumatology Department, Université Paris Cité, Cochin Hospital, Paris, France; ¹⁰Department of Rheumatology and Clinical Immunology Center, JLU Giessen, Campus Kerckhoff Bad Nauheim Germany; ¹¹Reumatologia, Azienda Ospedaliero-Universitaria Policlinico Umberto I, Roma, Italy; ¹²Section of Rheumatology, Department of Medicine, University of Verona, Verona, Italy; ¹³Centre for Rheumatology, Royal Free London and University College London Medical School, London, United Kingdom; ¹⁴Division of Rheumatology, A.O.U. Policlinico-San Marco, Catania, Italy; ¹⁵Department of Rheumatology, Clinical Immunology, Geriatrics and Internal Medicine, Medical University of Gdansk, Univers Gdansk Poland; ¹⁶Department of Rheumatology, University Hospital Strasbourg Strasbourg France; ¹⁷Department of rheumatology, Radboud University Nijmegen Medical Center Nijmegen The Netherlands; ¹⁸Department of Rheumatology, Leiden University Medical Center Leiden The Netherlands; ¹⁹Department of Rheumatology, Oslo University Hospital, Oslo, Norway; ²⁰Department of Rheumatology, University Hospital Zurich, University of Zurich, Zurich, Switzerland.

  Società Italiana di Reumatologia

  https://doi.org/10.4081/reumatismo.2025.2103

  123

• S13:6 | Investigating the intricate interplay between pulmonary functionality and advanced microangiopathy in very early diagnosis of systemic sclerosis Eugenio Capparelli¹, Eleonora Zaccara¹, Daniela Bompane¹, Elisabetta Ricchiuto², Giorgio Bonardi², Laura Castelnovo¹, Antonio Tamburello¹, Antonino Mazzone³, Paola Faggioli¹. | ¹Rheumatology Unit; ²Pneumology Unit; ³Internal Medicine Unit, ASST Ovest Milanese, Legnano, Italy.

  Società Italiana di Reumatologia

  https://doi.org/10.4081/reumatismo.2025.2104

  120

• S14:5 | Erosive hand osteoarthritis: premenopausal onset and more severe disease progression Marta Favero¹, Giacomo Cozzi¹, Clarissa Benvoluti¹, Laura Scagnellato¹, Gianluca Poncina¹, Stefano Rizzetto¹, Mariagrazia Lorenzin¹, Roberta Ramonda¹ | ¹UOC di Reumatologia, Dipartimento di Medicina-DIMED, Università di Padova, Italy

  Società Italiana di Reumatologia

  https://doi.org/10.4081/reumatismo.2025.2229

  140