Conventional radiography and correlated factors of enthesopathies of the Achilles tendon and plantar fascia in patients with axial spondyloarthritis

Ebru Yılmaz; Özge Pasin; Loiane Cristina de Souza; Guilherme Torres Vilarino; Alexandro Andrade; Camila Gusmão Vicente de Carvalho; Barbara Bayeh; Fernando Henrique Carlos de Souza; Renata Miossi; Pleiades Tiharu Inaoka; Takashi Matsushita; Naoki Mugii; Samuel Katsuyuki Shinjo

doi:10.4081/reumatismo.2024.1709

Vol. 77 No. s1 (2025): Abstract book of the 62th Conference of the Italian Society for Rheumatology, Rimini, 26-29 November 2025

376 articles Published 25 November 2025

62nd National Congress of the Italian Society of Rheumatology

376 articles

Welcome to the 62nd National Congress of the Italian Society of Rheumatology!

Andrea Doria

DOI https://doi.org/10.4081/reumatismo.2025.2231
- 703 abstract views
CO:01:1 | Efficacy and safety of rituximab across the four phenotypes of IgG4-related disease: a European multi-center cohort study of 115 patients

Marco Lanzillotta¹, Jens Vikse², Elisabetta Goni³, Veronica Batani¹, Jasmin Mahajne¹, Lorenzo Dagna¹, Emanuel Della Torre¹. | ¹Unit of Immunology, Rheumatology, Allergy, and Rare Disease, IRCCS Ospedale San Raffaele, Milano, Italy; ²Department of Rheumatology, Stavanger University Hospital, Norway; ³Department of Medicine II, University Hospital, Ludwig Maximilian University, Munich, Germany

Società Italiana di Reumatologia

DOI https://doi.org/10.4081/reumatismo.2025.1961
- 588 abstract views
CO:01:2 | BAG3 in systemic sclerosis: possible therapeutic target and biomarker for pulmonary fibrosis

Claudia Iannone^1|2, Margot De Marco³, Antonina Minniti¹, Paola Manzo³, Angela D'Ardia³, Antonia Falco³, Liberato Marzullo³, Angela Rosato³, Maria Caterina Turco³, Roberto Caporali^1|2, Nicoletta Del Papa^1|2. | ¹ASST G. Pini-CTO. UOC Clinica Reumatologica, Milano; ²Department of Clinical Sciences and Community Health, University of Milano; ³Department of Medicine, Surgery and Dentistry Schola Medica Salernitana, Baronissi (SA), Italy

Società Italiana di Reumatologia

DOI https://doi.org/10.4081/reumatismo.2025.1962
- 431 abstract views
CO:01:3 | Which PRO reflects remission best? Bridging the gap between patient and physician in systemic lupus erythematosus

Elena Ragusa¹, Elisabetta Chessa², Marta Paola Pireddu¹, Fabio Congiu¹, Giulia Rizzo¹, Marianna Salis¹, Alessandra Oliva¹, Mattia Congia², Alberto Cauli^1|2, Matteo Piga^1|2. | ¹SC Reumatologia, Dipartimento di Scienze Mediche e Salute Pubblica, Università di Cagliari; ²SC Reumatologia, AOU Cagliari, Italy

Società Italiana di Reumatologia

DOI https://doi.org/10.4081/reumatismo.2025.1963
- 442 abstract views
CO:01:4 | Identify predictors of relapse in idiopathic inflammatory myopathies: insights from an international cohort

Cristina Bochicchio^1|2, Maria Rosa Pellico^1|2, Claudia Iannone^1|2, Lekshmi Minikumari Rahulan³, Marco Fornaro⁴, Ilaria Cavazzana⁵, Edoardo Conticini⁶, Musataka Musataka⁷, Akira Yoshida⁷, Silvia Cavalli^1|2, Silvia Grazzini⁶, Giulio Fraticelli⁸, Alessia Gatti⁵, Giulio Lopinto⁴, Paolo Semeraro⁵, Veronica Batani⁸, Thomas Patric Sheeran⁹, Florenzo Iannone⁴, Giacomo De Luca⁸, Roberto Caporali^1|2, Latika Gupta^9|10|11, Nicoletta Del Papa². | ¹Department of Clinical Sciences and Community Health, University of Milano; ²Department of Rheumatology and Medical Sciences, ASST Gaetano Pini-CTO Institute, Milano, Italy; ³Rheumatology "Sanjay Gandhi" Postgraduate Institute of Medical Sciences, Lucknow, Uttar Pradesh, India; ⁴Unit of Rheumatology, Department of Precision and Regenerative Medicine, Area Jonica, University of Bari; ⁵Rheumatology and Clinical Immunology Unit, ASST Spedali Civili di Brescia; ⁶Rheumatology Unit, Department of Medicine, Surgery and Neurosciences, University of Siena, Italy; ⁷Department of Allergy and Rheumatology Nippon Medical School Graduate School of Medicine, Tokyo, Japan; ⁸Unit of Immunology, Rheumatology, Allergy and Rare Diseases, IRCCS San Raffaele Hospital, Milano, Italy; ⁹Department of Rheumatology, Royal Wolverhampton Hospitals NHS Trust, Wolverhampton, UK; ¹⁰Francis Crick Institute, London, UK; ¹¹School of Infection, Inflammation and Immunology, College of Medicine and Health, University of Birmingham, UK

Società Italiana di Reumatologia

DOI https://doi.org/10.4081/reumatismo.2025.1964
- 459 abstract views
CO:02:1 | Frequency and predictors of disease progression in contemporary seronegative undifferentiated arthritis in a treated-to-target early arthritis clinic

Elena Manna¹, Ludovico De Stefano^1|2, Domenico Sorace^1|2, Jacopo Pelizza^1|2, Blerina Xoxi^1|2, Antonio Manzo^1|2, Carlomaurizio Montecucco^1|2, Serena Bugatti^1|2. | ¹Department of Internal Medicine and Therapeutics, University of Pavia; ²Division of Rheumatology, IRCCS Policlinico San Matteo Foundation, Pavia, Italy

Società Italiana di Reumatologia

DOI https://doi.org/10.4081/reumatismo.2025.1965
- 396 abstract views
CO:02:2 | Effectiveness of tumor necrosis factor inhibitors in rheumatoid arthritis: real world data from an Italian National Registry

Valerio Fiorilli¹, Francesca Romana Spinelli¹, Florenzo Iannone², Chiara Bazzani³, Alberto Cauli⁴, Rosario Foti⁵, Marcello Govoni⁶, Francesco Paolo Cantatore⁷, Fabiola Atzeni⁸, Roberto Caporali⁹, Marco Sebastiani¹⁰, Roberta Ramonda¹¹, Serena Bugatti¹², Elisa Gremese¹³, Maria Sole Chimenti¹⁴, Bruno Frediani¹⁵, Maurizio Rossini¹⁶, Angelo Semeraro¹⁷, Leonardo Santo¹⁸, Gianfranco Ferraccioli¹⁹, Giovanni Lapadula²⁰, Fabrizio Conti¹. | ¹Dipartimento di Scienze Cliniche Internistiche, Anestesiologiche e Cardiovascolari, Sapienza Università di Roma; ²Dipartimento di Medicina di Precisione e Rigenerativa e Area Jonica, Università degli Studi Aldo Moro, Bari; ³ASST Spedali Civili di Brescia, Unità di Reumatologia ed Immunologia Clinica, Brescia; ⁴Dipartimento di Scienze Mediche e Sanità Pubblica, Università degli Studi di Cagliari; ⁵A.O.U. Policlinico S. Marco, UOS Reumatologia, Catania; ⁶Dipartimento di Scienze Mediche, Università di Ferrara; ⁷Unità di Reumatologia,Dipartimento di Medicina Specialistica, Università di Foggia; ⁸Dipartimento di Medicina Interna e Terapia Medica, UOC di Reumatologia, Università di Messina; ⁹Dipartimento di Scienze Cliniche e di Comunità, Università di Milano; ¹⁰Dipartimento di Medicina e Chirurgia, Università di Parma; ¹¹Unità di Reumatologia, Dipartimento di Medicina, Università di Padova; ¹²Dipartimento di Medicina Interna e Terapia Medica, Università di Pavia, ; ¹³IRCCS Istituto Clinico Humanitas, Dipartimento di Scienze Biomediche, Milano; ¹⁴Dipartimento di Medicina dei Sistemi, Università degli Studi di Roma-Tor Vergata, ; ¹⁵Dipartimento di Medicina Clinica e Scienze Immunologiche, Università di Siena; ¹⁶Dipartimento di Medicina, Università di Verona; ¹⁷Presidio Ospedaliero Valle d'Itria, Unità Operativa di Reumatologia, Martina Franca; ¹⁸Presidio Ospedaliero "Mons. Dimiccoli", Unità Operativa Semplice di Reumatologia, Barletta; ¹⁹Gruppo Italiano di Studio sulla Early Arthritis, GISEA, Roma; ²⁰Gruppo Italiano di Studio sulla early Arthritis, GISEA, Bari, Italy.

Società Italiana di Reumatologia

DOI https://doi.org/10.4081/reumatismo.2025.1966
- 375 abstract views
CO:02:4 | Whole blood hypercoagulable profiles in patients with rheumatoid arthritis

Lorenzo Di Luozzo¹, Alessandro Giollo¹, Mariangela Salvato¹, Francesca Frizzera¹, Kiren Khalid¹, Luca Spiezia², Andrea Benetti², Chiara Samà², Paolo Simioni², Andrea Doria¹. | ^1Unità di Reumatologia, Azienda Ospedaliera di Padova; ²Dipartimento di Medicina, Università di Padova, Italy

Società Italiana di Reumatologia

DOI https://doi.org/10.4081/reumatismo.2025.1967
- 403 abstract views
CO:03:1 | Distinct breath metabolomic signature in systemic sclerosis patients with pulmonary arterial hypertension

Martina Iacubino¹, Lorenzo Rocco¹, Marco Vicenzi^2|3, Chiara Bellocchi^2|4, Marta Mozzo⁴, Adriana Severino³, Monica Caronni³, Alessandro Santaniello³, Gaia Montanelli³, Barbara Vigone³, Liam Grimmett⁵, Matthew Kerr⁵, Lorenzo Beretta³. | ¹Scuola di specializzazione in Allergologia e Immunologia clinica, Università degli Studi di Milano; ²Dipartimento di Scienze Cliniche e Salute di Comunità, Dipartimento di Eccellenza 2023-2027, Università degli Studi di Milano; ³Dipartimento di Malattie Cardio-Toraciche-Vascolari, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milano; ⁴Dipartimento di Immunologia Clinica e Medicina Interna, Scleroderma Unit - Fondazione IRCCS Ca' Granda Ospedale Maggiore, Milano, Italy; ⁵Owlstone Medical, Cambridge, UK

Società Italiana di Reumatologia

DOI https://doi.org/10.4081/reumatismo.2025.1968
- 426 abstract views
CO:03:3 | Contribution of mitochondrial DNA to the onset and maintenance of inflammation in Systemic Sclerosis patients

Martina Orlandi¹, Giorgia Sinigaglia², Amelia Spinella¹, Isabella Martusciello², Marco De Pinto¹, Giorgia Roveta¹, Luca Keller¹, Marcello Pinti², Dilia Giuggioli¹ | ¹Dipartimento di scienze mediche e chirurgiche dei bambini e degli adulti, Università di Modena e Reggio Emilia, Italy; ²Università degli Studi di Modena e Reggio Emilia, Italy

Società Italiana di Reumatologia

DOI https://doi.org/10.4081/reumatismo.2025.2274
- 159 abstract views
CO:04:1 | Bone properties and biomechanics in patients with psoriatic disease: a cross-sectional study with high-resolution peripheral quantitative computed tomography

Anna Piccinelli¹, Francesco Bellinato², Francesco Pollastri¹, Francesco Giorgio¹, Martina Teoni¹, Angelo Fassio¹, Camilla Benini¹, Carmela Dartizio¹, Mattia Tugnolli¹, Davide Gatti¹, Maurizio Rossini¹, Ombretta Viapiana¹, Paolo Gisondi², Giovanni Adami¹. | ¹Rheumatology Unit, University of Verona; ²Dermatology Unit, University of Verona, Italy

Società Italiana di Reumatologia

DOI https://doi.org/10.4081/reumatismo.2025.1969
- 369 abstract views
CO:05:1 | Predicting one-year disease activity in systemic lupus erythematosus using machine learning and explainable AI

Pier Giacomo Cerasuolo¹, Augusta Ortolan¹, Livia Lilli², Laura Antenucci², Carlotta Maschiocchi², Jacopo Lenkowicz², Lucia Lanzo¹, Luca Petricca¹, Maria Rita Gigante¹, Vivianaantonella Pacucci¹, Pierluigi Rizzuti¹, Rebecca Ventura¹, Silvia Piunno¹, Cesare Gavotti¹, Marco Gorini³, Gabriella Castellino³, Alfredo Cesario², Stefano Patarnello², Silvia Laura Bosello¹, Maria Antonietta D'Agostino¹. | ¹UOC di Reumatologia ed Immunologia Clinica, Fondazione Policlinico A. Gemelli IRCCS, Università Cattolica del Sacro Cuore, Roma; ²Gemelli Generator, Fondazione Policlinico Universitario Agostino Gemelli IRCCS, Roma; ³AstraZeneca Italy, MIND, Milano, Italy

Società Italiana di Reumatologia

DOI https://doi.org/10.4081/reumatismo.2025.1970
- 409 abstract views
CO:05:2 | An OMERACT study for the development of an algorithm for automatic identification of calcium pyrophosphate deposition by ultrasound: the Crystal Artificial Intelligence Monitoring Study

Daniele Cirillo¹, Tito Bassani², Silvia Sirotti^1|2, Greta Pellegrino^1|2, Alessandro Lucia¹, Rodolfo Fabbri¹, Laura Pezzoni¹, Piercarlo Sarzi Puttini^1|2, Georgios Filippou^1|2. | ¹Università degli Studi di Milano; ²IRCCS Ospedale Galeazzi - Sant'Ambrogio, Milano, Italy

Società Italiana di Reumatologia

DOI https://doi.org/10.4081/reumatismo.2025.1971
- 417 abstract views
CO:05:3 | Radiomics and machine learning for differentiating rheumatoid arthritis-associated interstitial lung disease and idiopathic pulmonary fibrosis with usual interstitial pneumonia pattern

Vincenzo Venerito¹, Chiara Nani², Andreina Manfredi³, Marco Fornaro¹, Giuseppe Lopalco¹, Florenzo Iannone¹, Cecilia Burattini², Marco Sebastiani⁴. | ¹Rheumatology Unit, University of Bari; ²Respiratory Unit, Guglielmo da Saliceto Civil Hospital, Piacenza; ³Rheumatology Unit, Azienda Unità Sanitaria Locale-IRCCS di Reggio Emilia; ⁴Rheumatology Unit, AUSL Piacenza, University of Parma, Italy

Società Italiana di Reumatologia

DOI https://doi.org/10.4081/reumatismo.2025.1972
- 469 abstract views
CO:05:4 | Natural language processing reveals demographic features, comorbidities, and clinical domains to predict treatment longevity of b/tsDMARDs in psoriatic arthritis

Antonio Tonutti^1|2, Pierandrea Morandini³, Cosimo Faeti³, Nicoletta Luciano^1|2, Saverio D'Amico³, Victor Savevski³, Carlo Selmi^1|2 | ¹Department of Biomedical Sciences, Humanitas University Pieve Emanuele, Milan, Italy; ²Rheumatology and Clinical Immunology, IRCCS Humanitas Research Hospital Rozzano, Milan, Italy; ³Artificial Intelligence Unit, IRCCS Humanitas Research Hospital Rozzano, Milan, Italy

Società Italiana di Reumatologia

DOI https://doi.org/10.4081/reumatismo.2025.2275
- 170 abstract views
CO:06:1 | Predictors of damage accrual in a monocentric cohort of patients with Behçet’s syndrome (BS) evaluated with BS overall damage index in real-life clinical practice

Giulia Voltarel^1|2, Francesca Crisafulli^1|2, Alba Chiara Pozzi^1|2, Anita Melzani², Micol Frassi¹, Ilaria Cavazzana^1|2, Franco Franceschini^1|2, Paolo Airò¹. | ¹Rheumatology and Clinical Immunology Unit - ERN ReCONNET, ASST Spedali Civili of Brescia; ²Department of Clinical and Experimental Sciences, University of Brescia, Italy

Società Italiana di Reumatologia

DOI https://doi.org/10.4081/reumatismo.2025.1973
- 357 abstract views
CO:06:2 | Deep immunophenotyping in patients with juvenile localized scleroderma reveals two distinct immunological endophenotypes

Emiliano Marasco¹, Angela Aquilani¹, Rebecca Nicolai¹, Ivan Caiello¹, Fabrizio De Benedetti¹. | ¹Unità di Reumatologia, Ospdeale Pediatrico Bambino Gesù, Roma, Italy

Società Italiana di Reumatologia

DOI https://doi.org/10.4081/reumatismo.2025.1974
- 414 abstract views
CO:06:3 | Clinical and laboratory markers for distinguishing VEXAS from Schnitzler's syndrome in male patients with skin involvement: insights from the International AIDA Network Registries

Valeria Caggiano¹, Jessica Sbalchiero¹, Micol Frassi², Andrea Hinojosa-Azaola³, Francesca Crisafulli², Franco Franceschini², Paolo Sfriso⁴, Sara Bindoli⁴, José Hernández-Rodríguez⁵, Henrique A. Mayrink Giardini⁶, Giuseppe Lopalco⁷, Florenzo Iannone⁷, Ombretta Viapiana⁸, Amato De Paulis⁹, Lorenzo Dagna¹⁰, Antonio Gidaro¹¹, Serena Bugatti¹², Matteo Piga¹³, Fabrizio Conti¹⁴, Rosetta Vitetta¹⁵, Cecilia Chighizola¹⁶, Marcello Govoni¹⁷, Giacomo Emmi¹⁸, Paola Triggianese¹⁹, Carmelo Gurnari¹⁹, Bruno Frediani¹, Claudia Fabiani¹, Luca Cantarini¹, Antonio Vitale¹, for the AIDA Network¹ | ¹Department of Medical Sciences, Surgery and Neurosciences, University of Siena; ²University of Brescia, Italy; ³Department of Immunology and Rheumatology, Mexico City, Mexico; ⁴Rheumatology Unit, University of Padova, Italy; ⁵Clinical Unit of Autoinflammatory Diseases, Hospital Clínic of Barcelona, Spain; ⁶Rheumatology Division, Universidade de São Paulo, Brazil; ⁷University of Bari; ⁸Rheumatology Unit, University and Azienda Ospedaliera Universitaria Integrata of Verona; ⁹University of Napoli "Federico II"; ¹⁰Università Vita-Salute San Raffaele, Milano; ¹¹Luigi Sacco Hospital, University of Milano; ¹²Università di Pavia; ¹³University and AOU of Cagliari; ¹⁴AOU Policlinico Umberto I, Sapienza University of Rome; ¹⁵Unit of Rheumatology, ASL Sant' Andrea Hospital, Vercelli; ¹⁶University of Milano; ¹⁷Azienda Ospedaliero-Universitaria S. Anna, Ferrara; ¹⁸University of Trieste; ¹⁹University of Rome-Tor Vergata, Rome, Italy.

Società Italiana di Reumatologia

DOI https://doi.org/10.4081/reumatismo.2025.1975
- 475 abstract views
CO:07:1 | Assessing bone fragility in systemic sclerosis: results of the Sclerobone multicentric study

Giammarco De Mattia¹, Cristina Di Nicola², Davide Rozza², Manuel Sette³, Veronica Gerli³, Ludovica Pisapia¹, Chiara Sgorbini¹, Giulia Botticella⁴, Pamela Bernardini⁵, Francesca Bottazzi⁶, Francesca Lalli⁸, Luca Idolazzi⁷, Laura Bogliolo⁶, Monica Cesarotti⁸, Alessandra Rossi¹, Alessandra Della Rossa¹, Andrea Giusti⁴, Serena Guiducci⁵, Carlo Alberto Scirè², Addolorata Corrado⁹, Nicoletta Del Papa³, Marta Mosca¹, Chiara Crotti³, Maurizio Rossini⁷, Maurizio Mazzantini¹. | ¹UO Reumatologia, Dipartimento di Specialità Mediche e Chirurgiche, Azienda Ospedaliero-Universitaria Pisana, Pisa; ²Centro Studi SIR, Società Italiana di Reumatologia, Milano; ³UO Reumatologia, ASST Gaetano Pini-CTO, Milano; ⁴SC Reumatologia, Ospedale La Colletta, Azienda Sanitaria Locale 3 Liguria, Arenzano (GE); ⁵SOD Reumatologia, Azienda Ospedaliero-Universitaria Careggi, Firenze; ⁶SC Reumatologia, Fondazione IRCCS Policlinico San Matteo, Pavia; ⁷UOC Reumatologia, Azienda Ospedaliera Universitaria Integrata di Verona; ⁸SSD Reumatologia, Azienda Sanitaria Locale Perugia; ⁹Clinica Reumatologica Universitaria, Azienda Ospedaliero Universitaria di Foggia, Italy

Società Italiana di Reumatologia

DOI https://doi.org/10.4081/reumatismo.2025.1976
- 437 abstract views
CO:07:2 | Quantitative computed tomography analysis of pulmonary disease in systemic sclerosis: correlation between radiomics and pulmonary function tests

Francesco Pollastri¹, Loredana Carobene², Giovanni Adami¹, Michele Pernigotto³, Federico Aldegheri¹, Angela Ventura³, Claudio Micheletto², Susanna Baltieri³, Marco Sebastiani^4|6, Andreina Manfredi⁵, Davide Gatti¹, Maurizio Rossini¹, Angelo Fassio¹. | ¹UOC Reumatologia, Università degli Studi di Verona; ²UOC Pneumologia, Università degli Studi di Verona; ³ UOC Radiologia, Università degli Studi di Verona; ⁴Universita degli Studi di Parma; ⁵UUOC Reumatologia, Università degli Studi di Modena e Reggio Emilia; ⁶UOC Reumatologia, Azienda Unita' Sanitaria Locale, Piacenza, Italy

Società Italiana di Reumatologia

DOI https://doi.org/10.4081/reumatismo.2025.1977
- 382 abstract views
CO:07:3 | Does articular and entheseal structural damage drive pain and patient-driven reported outcomes in difficult-to-treat psoriatic arthrtis patients? Results from a cross-sectional study

Fabio Massimo Perrotta¹, Alen Zabotti², Mauro Fatica¹, Nicola Cabas², Andrea Guiotto², Nicoletta Franzolini³, Giovanni Striani², Maria De Martino⁴, Cristina De Nicola⁵, Miriam Isola⁴, Andrea Di Matteo⁶, Gabriele De Marco⁶, Denis McGonagle⁶, Ennio Lubrano¹, Luca Quartuccio⁴. | ¹Università degli studi del Molise, Campobasso; ²University Hospital Santa Maria della Misericordia, Udine; ³Presidio Ospedaliero S. Antonio, San Daniele del Friuli (UD); ⁴University of Udine; ⁵Epidemiology Unit, Italian Society for Rheumatology, Milano, Italy; ⁶University of Leeds, Leeds, UK

Società Italiana di Reumatologia

DOI https://doi.org/10.4081/reumatismo.2025.1978
- 340 abstract views
CO:07:4 | Clinical and psychosocial domains in fibromyalgia: a multidimensional questionnaire approach for personalized management. Results from an Italian monocentric study

Eleonora Pedretti¹, Francesca Regola¹, Giulia Fontana^1|2, Giulia Voltarel^1|2, Michela Riolfo^1|2, Anna Scalvini¹, Ilaria Cavazzana^1|2, Franco Franceschini^1|2, Roberto Gorla¹. | ¹Rheumatology and Clinical Immunology Unit - ERN ReCONNET, ASST Spedali Civili of Brescia; ²Department of Clinical and Experimental Sciences, University of Brescia, Italy

Società Italiana di Reumatologia

DOI https://doi.org/10.4081/reumatismo.2025.1979
- 422 abstract views
CO:07:5 | Enhanced fibroblast signatures in females with early rheumatoid arthritis highlights a potential basis for poorer treatment outcomes

Benedetta Monosi¹, James Perera², Alessandra Nerviani^2|3, Maria Sole Chimenti¹, Felice Rivellese^2|3, Costantino Pitzalis^2|3|4. | ¹Rheumatology, Allergology and Clinical Immunology, Department of Systems Medicine, University of Rome Tor Vergata, Rome, Italy; ²Centre for Experimental Medicine and Rheumatology, William Harvey Research Institute, Queen Mary University of London, London, UK; ³Barts Health NHS Trust and Barts Biomedical Research Centre, National Institute for Health and Care Research, London, UK; ⁴Department of Biomedical Sciences Humanitas University and IRCCS Humanitas Research Hospital, Milano, Italy

Società Italiana di Reumatologia

DOI https://doi.org/10.4081/reumatismo.2025.1980
- 4,004 abstract views
CO:07:6 | Hidden in plain sight: fibromyalgia prevalence and correlates in 3,000 non-clinical Italian subjects

Sergio Del Vescovo¹, Vincenzo Venerito¹, Maria Giannotta¹, Maria Grazia Anelli¹, Maria Morrone¹, Angelo Troiano¹, Marco Capodiferro¹, Marco Fornaro¹, Giuseppe Lopalco¹, Florenzo Iannone¹. | ¹UOC Reumatologia, DiMePre-J, Policlinico di Bari, Italy

Società Italiana di Reumatologia

DOI https://doi.org/10.4081/reumatismo.2025.1981
- 442 abstract views
CO:08:1 | Aquaporin-4 downregulation in dysphagic idiopathic inflammatory myopathies: association with Type 2 fiber damage and inflammation

Marco Fornaro¹, Margherita Giannini², Dario D'Abbicco³, Maria Luisa Fiorella⁴, Antonio Frigeri⁵, Francesco Girolamo⁶, Florenzo Iannone¹. | ¹Unit of Rheumatology, Department of Precision and Regenerative Medicine and Ionian Area, Bari, Italy; ²Physiologie et Explorations Fonctionnelles Musculaires, University Hospital of Strasbourg, Strasburgo, France; ³Institute of General Surgery G Marinaccio, Department of Precision and Regenerative Medicine and Ionian Area, Bari; ⁴Unit of Otolaryngology, Department of Translational Biomedicine and Neuroscience DiBraiN, Bari; ⁵Unit of Human Physiology, Department of Translational Biomedicine and Neuroscience DiBraiN, Bari; ⁶Unit of Human Anatomy and Histology, Department of Translational Biomedicine and Neuroscience DiBraiN, Bari, Italy

Società Italiana di Reumatologia

DOI https://doi.org/10.4081/reumatismo.2025.1982
- 303 abstract views
CO:08:2 | Impact of comorbidities on clinical-serological phenotype of primary Sjögren's disease: a retrospective analysis of a multicenter cohort

Roberto Dal Pozzolo¹, Maria Letizia Currò², Giacomo Cafaro¹, Valeria Manfrè³, Gaetano La Rocca⁴, Alessia Alunno⁵, Francesco Carubbi⁵, Nicoletta Del Papa⁶, Viktoriya Pavlych⁷, Ilenia Fischetti⁸, Letizia Pia Di Corcia⁹, Pamela Bernardini¹⁰, Luca Quartuccio³, Chiara Baldini⁴, Paola Cipriani⁷, Roberta Priori⁸, Onorina Berardicurti⁹, Serena Guiducci¹⁰, Serena ColaFrancesco¹¹, Fabiola Atzeni², Elena Bartoloni¹. | ¹SC Reumatologia. Università di Perugia; ²Unità di Reumatologia. Università di Messina; ³Unità di Reumatologia, Università di Udine; ⁴Unità di Reumatologia. Università di Pisa; ⁵Divisione di Medicina Interna e Nefrologia. Università di L'Aquila; ⁶Dipartimento di Reumatologia. Università di Milano; ⁷Unità di Reumatologia, Università di L'Aquila; ⁸UOC Reumatologia. Università Sapienza, Roma; ⁹Unità di Reumatologia. Università Campus Biomedico, Roma; ¹⁰Unità di Reumatologia. Università di Firenze; ¹¹Reumatologia e Immunologia Clinica. IRCCS Humanitas, Milano, Italy

Società Italiana di Reumatologia

DOI https://doi.org/10.4081/reumatismo.2025.1983
- 354 abstract views
CO:08:4 | Paraproteinemias in Sjögren’s disease: cryoglobulinemia and monoclonal component define distinct phenotypes with a synergistic lymphoproliferative risk

Maria Teresa Rizzo¹, Simone Longhino¹, Giacomo Cafaro², Valeria Manfrè¹, Francesco Carubbi³, Alessia Alunno³, Piera Altieri³, Nicoletta Del Papa⁴, Paola Cipriani⁵, Fabiola Atzeni⁶, Francesca Cracò⁶, Onorina Berardicurti⁷, Andrea Pilato⁷, Roberta Priori⁸, Angelica Gattamelata⁸, Serena Guiducci⁹, Chiara Baldini¹⁰, Beatrice Dei¹⁰, Pamela Bernardini⁹, Elena Bartoloni², Luca Quartuccio¹ | ¹Clinica di Reumatologia, Ospedale Santa Maria della Misericordia, Azienda Sanitaria Universitaria Friuli Centrale AS Udine; ²SC Reumatologia, Dipartimento di Medicina e Chirurgia, Università di Perugia; ³Unità operativa di Medicina Interna e Nefrologia, Dipartimento delle Scienze della Vita, della Salute e dell Ambiente L'Aquila; ⁴Unità operativa di Sclerodermia, Dipartimento di Reumatologia, ASST G. Pini-CTO, Università degli Studi di Milano; ⁵Unità operativa di Reumatologia, Dipartimento di Scienze Cliniche Applicate e Biotecnologiche, Università dell'Aquila; ⁶UOC di Reumatologia, Dipartimento di Medicina Interna e Sperimentale, Università di Messina; ⁷UOC di Immuno-Reumatologia, Dipartimento di Medicina e Chirurgia, Università Campus Bio-Medico di Roma; ⁸UOC Reumatologia, Sapienza Università di Roma; ⁹SOD Reumatologia, Dipartimento di Medicina Sperimentale e Clinica, Università degli Studi di Firenze; ¹⁰Clinica di Reumatologia, Dipartimento di Medicina Clinica e Sperimentale, Università di Pisa, Italy

Società Italiana di Reumatologia

DOI https://doi.org/10.4081/reumatismo.2025.2119
- 1,173 abstract views
CO:08:5 | Clinical impact of anti-Ro52 antibodies in idiopathic inflammatory myopathies: insights from a multicenter Italian cohort

Paola Bizioli¹, Cesare Tomasi², Francesca Bellisai³, Francesca Buzzulini⁴, Antonio Tonutti^5|6, Angela Ceribelli^5|6, Edoardo Conticini³, Anna Ghirardello⁷, Luca Iaccarino⁷, Danilo Villalta⁴, Franco Franceschini¹, Ilaria Cavazzana¹. | ¹Rheumatology and Clinical Immunology Unit - ERN ReCONNET, ASST Spedali Civili of Brescia; ²Department of Clinical and Experimental Sciences, University of Brescia; ³Department of Medicine, Surgery and Neurosciences, Rheumatology Unit, University of Siena; ⁴Department of Laboratory Immunology and Allergology, Santa Maria degli Angeli Hospital, Pordenone; ⁵Department of Biomedical Sciences, Humanitas University, Rozzano (MI); ⁶Rheumatology and Clinical Immunology, Istituti di Ricovero e Cura a Carattere Scientifico, Humanitas Research Hospital, Rozzano (MI); ⁷Division of Rheumatology, Department of Medical and Surgical Sciences, University of Padova, Italy

Società Italiana di Reumatologia

DOI https://doi.org/10.4081/reumatismo.2025.1984
- 357 abstract views
CO:08:6 | Prevalence, incidence and survival in interstitial lung disease secondary to primary Sjögren’s syndrome. Results from the “EMERGE” longitudinal study

Alessandra Rai¹, Caterina Vacchi², Stefania Cerri³, Roberta Eufrasia Ledda⁴, Giulia Cassone², Dario Andrisani³, Filippo Gozzi³, Lucia Dardani¹, Fabiola Atzeni⁵, Athina Patsoura³, Francesca Cozzini¹, Marco Sebastiani⁶, Andreina Manfredi¹. | ¹USL-IRCCS Reggio Emilia, University of Modena and Reggio Emilia; ²Azienda Ospedaliero Universitaria Policlinico di Modena; ³Pulmonology Unit, AOU Policlinico di Modena, University of Modena and Reggio Emilia; ⁴Radiology Unit, Azienda Ospedaliera di Parma, University of Parma; ⁵ Policlinico Gaetano Martino, University of Messina; ⁶Azienda Ospedaliera di Piacenza,University of Parma, Italy

Società Italiana di Reumatologia

DOI https://doi.org/10.4081/reumatismo.2025.1985
- 687 abstract views
CO:09:1 | The impact of sex and gender on fibromyalgia syndrome: data from the Italian Fibromyalgia Registry

Martina Favretti¹, Cristina Iannuccelli², Giulio Dolcini¹, Sonia Farah³, Marco Di Carlo³, Giuseppina Tramontano⁴, Giorgia Ferrari⁴, Fabiola Atzeni⁵, Greta Pellegrino^6|7, Piercarlo Sarzi-Puttini^6|7, Fausto Salaffi³, Manuela Di Franco⁸. | ¹Dipartimento di Medicina Molecolare, Sapienza Università di Roma; ²UOC Reumatologia, Policlinico Umberto I, Roma; ³Unità di Reumatologia, Dipartimento di Scienze Cliniche e Molecolari, Università Politecnica delle Marche, Jesi (AN); ⁴Unità di Reumatologia, Dipartimento di Specialità Mediche, Regional Health Trust 3, Genova; ⁵Unità di Reumatologia, Dipartimento di Medicina Interna, Università di Messina; ⁶Unità di Reumatologia, IRCCS Ospedale Galeazzi - Sant'Ambrogio, Milano; ⁷Dipartimento di Scienze Biomediche e Cliniche, Università degli studi di Milano; ⁸UOC Reumatologia, Dipartimento di Scienze Cliniche Internistiche Anestesiologiche e Cardiovascolari, La Sapienza, Roma, Italy

Società Italiana di Reumatologia

DOI https://doi.org/10.4081/reumatismo.2025.1986
- 390 abstract views
CO:09:2 | Mapping Emotional Function in Fibromyalgia: Integrating Alexithymia, Pain Catastrophizing and Self-Compassion

Francesca Trunfio¹, Damiano Currado^1|2, Rosa Bruni³, Barbara Biticchi¹, Francesca Saracino¹, Erika Corberi¹, Ludovica Lamberti¹, Annalisa Marino^1|2, Lyubomyra Kun¹, Leonardo Frasca'¹, Sebastiano Lorusso¹, Marta Vomero², Onorina Berardicurti^1|2, Roberto Giacomelli^1|2, Luca Navarini^1|2 | ¹Rheumatology and Clinical Immunology, Department of Medicine, University of Rome Campus Biomedico, School of Medicine, Rome, Italy; ²Clinical and Research Section of Rheumatology and Clinical Immunology, Fondazione Policlinico Campus Biomedico, Rome, Italy; ³Psychiatrist, Psychotherapist, certified Teacher Mindful Self-Compassion Program, contract Professor at University Campu Rome, Italy

Società Italiana di Reumatologia

DOI https://doi.org/10.4081/reumatismo.2025.2276
- 127 abstract views
CO:09:3 | Effectiveness and safety of nintedanib in autoimmune systemic diseases: real life data from an Italian multicentre study (Island group) of the Italian Society of Rheumatology

Corrado Campochiaro¹, Paola Conigliaro², Gianluca Sambataro³, Marco Matucci-Cerinic¹, Marco Sebastiani⁴, Gianluca Bajocchi⁵, Angelo Fassio⁶, Elena Treppo⁷, Elisabetta Zanatta⁸, Elena Bartolini⁹, Francesco Ferro¹⁰, Chiara Bazzini¹¹, Nicoletta Del Papa¹², Gemma Lepri¹³, Andrea Lo Monaco¹⁴, Marta Favero¹⁵, Annamaria Iuliano¹⁶, Francesca Li Gobbi¹⁷, Maria Sole Chimenti², Giuseppe Muscato¹⁸, Giacomo De Luca¹, Francesca Cozzini⁴, Lucia Dardani⁵, Francesco Pollastri⁶, Alessandro Gattron⁷, Beatrice Moccaldi⁸, Caterina Antonini⁹, Gaetano La Rocca¹⁰, Ilaria Cavazzana¹¹, Andreina Manfredi^5|19. | ¹IRCCS San Raffaele Hospital, Vita-Salute San Raffaele, Milano; ²U.O.C. Reumatologia Dipartimento di Medicina dei Sistemi Università di Roma-Tor Vergata, Roma; ³Università Kore, Enna; ⁴University of Parma, Azienda Ospedaliera di Piacenza; ⁵UOC Reumatologia, AUSL IRCCS Reggio Emilia; ⁶UOC Reumatologia Università degli Studi di Verona; ⁷Dipartimento di Medicina, Clinica di Reumatologia, Università degli Studi di Udine; ⁸UOC Reumatologia, Dipartimento di Medicina DIMED, Azienda Ospedale Università di Padova; ⁹SC Interaziendale di Reumatologia, Dipartimento di Medicina e Chirurgia, Università di Perugia, Azienda Integrata Università; ¹⁰Dipartimento di Medicina Clinica e Sperimentale UO Reumatologia-Universitaria AOU Pisa; ¹¹U.O. Reumatologia e Immunologia Clinica ASST Spedali Civili di Brescia; ¹²Clinica Reumatologica, Milano; ¹³S.O.D. di Reumatologia AOU Careggi, Firenze; ¹⁴UOC Reumatologia Azienda Ospedaliero-Universitaria Sant'Anna, Ferrara; ¹⁵Internal Medicine I, Department of Medicine, Ca' Foncello Hospital, AULSS2 Marca Trevigiana, Treviso; ¹⁶UOC Reumatologia, AO San Camillo Forlanini, Roma; ¹⁷Rheumatology Unit, S.Giovanni di Dio Hospital, Firenze; ¹⁸Department of Clinical and Experimental Medicine, Regional Referral Center for Rare Lung Disease, Policlinico, Catania; ¹⁹Università degli Studi di Modena e Reggio Emilia, Italy

Società Italiana di Reumatologia

DOI https://doi.org/10.4081/reumatismo.2025.1987
- 635 abstract views
CO:09:4 | Erosive hand osteoarthritis: the impact of comorbidities in the context of joint disease

Sara Bindoli¹, Clarissa Benvoluti¹, Giacomo Cozzi¹, Marta Favero¹, Mariagrazia Lorenzin¹, Andrea Doria¹, Paolo Sfriso¹, Roberta Ramonda¹. | ¹UOC Reumatologia, Dipartimento di Medicina, Università degli studi di Padova, Italy

Società Italiana di Reumatologia

DOI https://doi.org/10.4081/reumatismo.2025.1988
- 385 abstract views
CO:09:5 | LDL-cholesterol goal attainment with ezetimibe and bempedoic acid in patients with rheumatoid arthritis: a simulation study in the Italian CORDIS cohort

Alessandro Giollo¹, Kiren Khalid¹, Luca Bonanni², Nicola Ferri³, Gianluca Erre⁴, Matteo Piga⁵, Elena Bartoloni⁶, Andreina Manfredi⁷, Enno Giulio Favalli⁸, Maria Sole Chimenti⁹, Serena Guiducci¹⁰, Eleonora Celletti¹¹, Addolorata Corrado¹², Simone Parisi²⁰, Ivan Giovannini¹³, Elisa Gremese¹⁴, Garifallia Sakellariou¹⁵, Ombretta Viapiana¹⁶, Marco Fornaro¹⁹, Fabiola Atzeni¹⁷, Francesca Romana Spinelli¹⁸, Fabio Cacciapaglia¹⁹ | ¹Università di Padova Padova, Italy; ²UO Medicina Interna ULSS3 Mestre, Italy; ³Università di Padova, Department of Pharmaceutical and Pharmacological Sciences, University of Padova Padova, Italy; ⁴Università di Sassari Sassari, Italy; ⁵Università di Cagliari Cagliari, Italy; ⁶Univeristà degli studi di Perugia Perugia, Italy; ⁷Università di Modena e Reggio Emilia, UO di Reumatologia Ospedale Policlinico di Modena Reggio Emilia, Italy; ⁸IRCCS Humanitas Research Hospital, Rozzano Milano, Italy; ⁹Università Tor Vergata Roma, Italy; ¹⁰Università di Firenze Firenze, Italy; ¹¹Ospedale SS. Annunziata Chieti, Italy; ¹²Università degli studi di Foggia Foggia, Italy; ¹³Università di Udine, Clinica di Reumatologia Udine, Italy; ¹⁴Università degli studi di Milano Milano, Italy; ¹⁵Università degli Studi di Pavia Pavia, Italy; ¹⁶Università di Verona Verona, Italy; ¹⁷Università degli Studi di Messina Messina, Italy; ¹⁸Università La Sapienza Roma, Italy; ¹⁹Università di Bari, Reumatologia Universitaria Policlinico di Bari Bari, Italy; ²⁰S.C. di Reumatologia A.O.U. Città della Salute e della Scienza di Torino - Ospedale Molinette Torino, Italy

Società Italiana di Reumatologia

DOI https://doi.org/10.4081/reumatismo.2025.2277
- 104 abstract views
CO:09:6 | Risk of disease flare during pregnancy and postpartum in inflammatory arthritis: association with therapy discontinuation in the prospective P-RHEUM.it study

Dina Zucchi¹, Chiara Tani¹, Francesca Crisafulli², Alessia Gatti², Maria Gerosa³, Cecilia Chighizola³, Melissa Padovan⁴, Salvatore D'Angelo⁵, Florenzo Iannone⁶, Maria Sole Chimenti⁷, Claudia Lomater⁸, Francesca Serale⁹, Veronique Ramoni¹⁰, Oscar Epis¹¹, Bernd Raffeiner¹², Ariela Hoxha¹³, Andrea Doria¹⁴, Leonardo Santo¹⁵, Valentina Canti¹⁶, Francesca Bellisai¹⁷, Giovanna Cuomo¹⁸, on behalf of the P-Rheumit Investigators¹⁹, Greta Carrara²⁰, Cristina Di Nicola²⁰, Davide Rozza²⁰, Carlo Alberto Scirè²⁰, Maria Chiara Gerardi¹¹, Angela Tincani², Laura Andreoli², Marta Mosca¹. | ¹Rheumatology Unit, University of Pisa and Azienda Ospedaliero Universitaria Pisana; ²Rheumatology and Clinical Immunology Unit, ASST Spedali Civili, Brescia; ³Clinical Rheumatology Division, ASST Gaetano Pini-CTO and University of Milano; ⁴Rheumatology Unit, Azienda Ospedaliero-Universitaria S. Anna and University of Ferrara; ⁵Rheumatology Department of Lucania - San Carlo Hospital, Potenza; ⁶Rheumatology Unit, DiMePRE-J, University of Bari; ⁷Department of Systems Medicine, Rheumatology, Allergology and Clinical Immunology, University of Rome-Tor Vergata, Roma; ⁸Torino Academic Rheumatology Center, A.O. Mauriziano di Torino, University of Torino; ⁹Rheumatology Unit, ASL CN1 Cuneo; ¹⁰Internal Medicine Department, ASST Lodi - Ospedale Maggiore di Lodi; ¹¹Division of Rheumatology, Multispecialist Medical Department, Grande Ospedale Metropolitano Niguarda, Milano; ¹²Department of Rheumatology, Central Hospital of Bolzano SABES-ASDAA, Bolzano; ¹³General Medicine and Thrombosis and Hemorrhagic Unit, Department of Medicine, University of Padova; ¹⁴Rheumatology Unit, Department of Medicine, University of Padova; ¹⁵Rheumatology Unit, Mons. Dimiccoli Hospital, Barletta; ¹⁶Division of Immunology, Transplantation and Infectious Diseases, IRCCS Ospedale San Raffaele, Milano; ¹⁷Rheumatology Unit, Department of Medicine, Surgery and Neurosciences, University of Siena; ¹⁸Precision Medicine Department, University of Campania L. Vanvitelli, Napoli; ¹⁹The Italian Society for Rheumatology; ²⁰Epidemiology Research Unit of the Italian Society for Rheumatology, Milano, Italy

Società Italiana di Reumatologia

DOI https://doi.org/10.4081/reumatismo.2025.1989
- 424 abstract views
CO:10:1 | High-grade synovitis and histological pathotype distribution in patients with advanced osteoarthritis undergoing joint replacement: a more inflammatory disease than we thought?

Jacopo Ciaffi¹, Lorenzo Bianchi¹, Luana Mancarella², Federica Pignatti², Veronica Brusi², Lucia Lisi², Simona Neri², Elisa Assirelli², Alberto Righi³, Marco Gambarotti³, Francesco Ursini¹. | ¹SSD Medicina e Reumatologia, IRCCS Istituto Ortopedico Rizzoli, Alma Mater Studiorum Università di Bologna; ²SSD Medicina e Reumatologia, IRCCS Istituto Ortopedico Rizzoli, Bologna; ³SSD di Anatomia e Istologia Patologica, IRCCS Istituto Ortopedico Rizzoli, Bologna, Italy

Società Italiana di Reumatologia

DOI https://doi.org/10.4081/reumatismo.2025.1990
- 355 abstract views
CO:10:2 | Common variable immunodeficiency patients complicated by autoimmune and inflammatory rheumatic manifestations reveal high frequency of genetic variants potentially linked to inborn errors of immunity

Paolo Semeraro¹, Micol Frassi¹, Silvia Clara Giliani², Franco Franceschini¹, Paolo Airò¹. | ¹Rheumatology and Clinical Immunology Unit, ERN ReCONNET, ASST Spedali Civili of Brescia and University of Brescia; ²Medical Genetic Laboratory, ASST Spedali Civili of Brescia and University of Brescia, Italy

Società Italiana di Reumatologia

DOI https://doi.org/10.4081/reumatismo.2025.1991
- 1,107 abstract views
CO:10:3 | Clinical response to JAK inhibitors or non-TNFi-targeted biologicals according to synovial tissue characteristics in patients with difficult-to-treat rheumatoid arthritis

Mariangela Salvato¹, Alessandro Giollo¹, Francesca Frizzera¹, Kiren Khalid¹, Lorenzo Di Luozzo¹, Maria Capita¹, Marianna Tamussin¹, Carlo Garaffoni², Marny Fedrigo³, Annalisa Angelini³, Ettore Silvagni², Andrea Doria¹. | ¹Rheumatology Unit, Department of Medicine - DIMED, University of Padova; ²Rheumatology Unit, Department of Medical Sciences, University of Ferrara and Azienda Ospedaliero-Universitaria S. Anna; ³Cardiovascular Pathology, Department of Cardiac, Thoracic, Vascular Sciences and Public Health, University of Padova, Italy

Società Italiana di Reumatologia

DOI https://doi.org/10.4081/reumatismo.2025.1992
- 382 abstract views
CO:10:4 | Lung vasculature quantification on computed tomography predicts new onset of interstitial lung disease in systemic sclerosis

Maria Iacovantuono^1|2, Nicholas Landini^2|3, Lisa Jungblut⁴, Gesa Sauer², Rucsandra Dobrota², Maria Sinziana Muraru-Carbune², Muriel Elhai², Carmen-Marina Mihai², Mike Oliver Becker², Maria Sole Chimenti¹, Thomas Frauenfelder⁴, Anna-Maria Hoffmann-Vold⁵, Oliver Distler², Cosimo Bruni². | ¹Rheumatology, Allergology and Clinical Immunology, Department of Systems Medicine, Tor Vergata University, Rome, Italy; ²Department of Rheumatology, University Hospital Zurich, University of Zurich, Switzerland; ³Department of Radiological Sciences, Oncology and Pathology, Sapienza University, Policlinico Umberto I, Rome, Italy; ⁴Institute for Diagnostic and Interventional Radiology, University Hospital Zurich, University Zurich, Switzerland; ⁵Department of Rheumatology, Oslo University Hospital, Norway

Società Italiana di Reumatologia

DOI https://doi.org/10.4081/reumatismo.2025.1993
- 319 abstract views
CO:10:5 | Beyond major glands: high-resolution ultrasound mapping of labial salivary and lacrimal gland involvement in Sjögren’s disease

Giovanni Fulvio¹, Rossana Izzetti², Valentina Donati³, Caterina Porciani⁴, Silvia Fonzetti¹, Gaetano La Rocca¹, Beatrice Dei¹, Francesco Ferro¹, Marta Mosca¹, Chiara Baldini¹. | ¹Rheumatology Unit, Department of Clinical and Experimental Medicine, University of Pisa; ²Unit of Dentist, Department of Surgical, Medical and Molecular Pathology and Critical Care Medicine University of Pisa; ³Azienda Ospedaliero-Universitaria Pisana, Unit of Pathological Anatomy, Pisa; ⁴Immunology and Allergology Unit, Department of Clinical and Experimental Medicine, Pisa, Italy

Società Italiana di Reumatologia

DOI https://doi.org/10.4081/reumatismo.2025.1994
- 329 abstract views
CO:10:6 | Impact of pregnancy on organ damage in systemic lupus erythematosus: a prospective multicenter study

Giancarlo Cascarano¹, Greta Hulej², Dina Zucchi¹, Antonia Calligaro², Elena Elefante¹, Luca Iaccarino², Sabrina Gori¹, Margherita Zen², Chiara Tani¹, Andrea Doria², Marta Mosca¹. | ¹Università degli Studi di Pisa; ²Università degli Studi di Padova, Italy

Società Italiana di Reumatologia

DOI https://doi.org/10.4081/reumatismo.2025.1995
- 391 abstract views
CO:11:2 | Systemic lupus erythematosus with major neuropsychiatric involvement treated with anifrolumab: literature review and a case report

Giulia Rizzo¹, Fabio Congiu¹, Elisabetta Chessa², Marta Paola Pireddu¹, Elena Ragusa¹, Alessandra Oliva¹, Marianna Salis¹, Alberto Cauli^1|2, Matteo Piga^1|2 | ¹SC Reumatologia, Dipartimento di Scienze Mediche e Salute Pubblica, Università di Cagliari Italy; ²SC Reumatologia, AOU Cagliari Italy

Società Italiana di Reumatologia

DOI https://doi.org/10.4081/reumatismo.2025.2120
- 638 abstract views
CO:11:3 | Belimumab for lupus nephritis patients with poor kidney function: a post-hoc analysis of the bliss-ln trial

Giacomo Emmi^1|2, Ersilia Lucenteforte³, Giorgio Limoncella³, Emanuele Chiara^1|2, Marta Calatroni^4|5, Gabriella Moroni^4|5 | ¹Clinical Medicine and Rheumatology Unit, Cattinara University Hospital, Trieste, Italy; ²Department of Medical, Surgical and Health Sciences, University of Trieste, Trieste, Italy; ³Department of Statistics, Informatics and Applications Giuseppe Parenti, University of Florence, Florence, Italy; ⁴Department of Biomedical Sciences, Humanitas University, Pieve Emanuele, Milan, Italy; ⁵Nephrology and Dialysis Division, IRCCS Humanitas Research Hospital, Milan, Italy

Società Italiana di Reumatologia

DOI https://doi.org/10.4081/reumatismo.2025.2278
- 206 abstract views
CO:11:4 | Unveiling frailty in active systemic lupus erythematosus in the modern era of rheumatology: first real-life use of the SLICC-FI in a cohort diagnosed after 2000

Angela Elia¹, Dina Zucchi², Michele Moretti¹, Elena Elefante², Chiara Cardelli¹, Linda Carli², Viola Signorini², Chiara Stagnaro², Chiara Tani¹, Marta Mosca¹. | ¹U.O. di Reumatologia, Dipartimento di Medicina Clinica e Sperimentale, Università di Pisa; ²U.O Reumatologia, Azienza Ospedaliero Universitaria Pisana, Pisa, Italy

Società Italiana di Reumatologia

DOI https://doi.org/10.4081/reumatismo.2025.1996
- 396 abstract views
CO:11:5 | Laboratory preliminary results from an open label, prospective, phase ii descriptive pilot trial of belimumab therapy for refractory and/or non criteria manifestations of antiphospholipid syndrome

Alice Barinotti¹, Massimo Radin¹, Irene Cecchi¹, Beatrice Ala¹, Chiara Raymondi¹, Elena Rubini¹, Silvia G. Foddai¹, Lois Ira Maniulit Capulong¹, Alessio Conti¹, Alessandro Morotti¹, Dario Roccatello¹, Roberta Fenoglio¹, Savino Sciascia¹. | ¹Università di Torino, Italy.

Società Italiana di Reumatologia

DOI https://doi.org/10.4081/reumatismo.2025.1997
- 406 abstract views
CO:11:6 | Off-therapy remission in systemic lupus erythematosus: the BLys lupus flare index (BLyFI) as a decision tool for immunosuppressive therapy withdrawal in remitted patients

Noemi Merra¹, Anna Giorgia Osele¹, Davide Ragno¹, Greta Hulej¹, Zahrà Rahmé¹, Ilenia Anna Gennaio¹, Filippo Vesentini¹, Margherita Zen¹, Luca Iaccarino¹, Andrea Doria¹ | Università degli Studi di Padova, Italy

Società Italiana di Reumatologia

DOI https://doi.org/10.4081/reumatismo.2025.2121
- 311 abstract views
CO:12:1 | Inside the Heterogeneity of Primary Central Nervous System Vasculitis: A single-centre 40-year experience

Carlo Salvarani¹, Gene G Hunder², Caterina Giannini², Teresa Jh Christianson², Robert D Brown² | ¹Azienda USL-IRCCS di Reggio Emilia e UNIMORE Reggio Emilia, Italy; ²Mayo Clinic Rochester, USA

Società Italiana di Reumatologia

DOI https://doi.org/10.4081/reumatismo.2025.2279
- 103 abstract views
CO:12:2 | Circulating cell signatures of disease activity in ANCA-associated vasculitis using automated hematologic profiling analysis with Sysmex XN-9000®: preliminary results from a monocentric cohort

Federica Davanzo¹, Luca Iorio¹, Veronica Davanzo², Michela Pelloso², Eleonora Fiorin¹, Roberta Prevedello¹, Francesca Tosato², Martina Montagnana³, Roberto Padoan¹, Andrea Doria¹ | ¹Rheumatology Unit, Department of Medicine DIMED, University of Padua Padova, Italy; ²Laboratory Medicine Unit, Biomedical Sciences Department-DSB, University of Padua Padova, Italy; ³Department of Medicine DIMED, University of Padua Padova, Italy

Società Italiana di Reumatologia

DOI https://doi.org/10.4081/reumatismo.2025.2280
- 124 abstract views
CO:12:4 | Predicting 12-month clinical relapse in Takayasu arteritis using ^[18F]FDG PET and convolutional neural networks

Alessandro Tomelleri¹, Carolina Bezzi², Sara Resta², Corrado Campochiaro¹, Federico Fallanca², Elena Baldissera¹, Samuele Ghezzo², Nicola Farina¹, Arturo Chiti², Paola Mapelli², Marco Matucci-Cerinic¹, Maria Picchio², Lorenzo Dagna¹. | ¹IRCCS Ospedale San Raffaele, Unità di Immunologia Reumatologia Allergologia e Malattie Rare, Milano; ²IRCCS Ospedale San Raffaele, Unità di Medicina Nucleare, Milano, Italy

Società Italiana di Reumatologia

DOI https://doi.org/10.4081/reumatismo.2025.1998
- 365 abstract views
CO:12:5 | Aortic inflammation and aneurysm risk in giant cell arteritis: a multicenter imaging study

Caterina Ricordi¹, Chiara Marvisi¹, Konstanze V. Guggenberger², Rudolf A. Werner³, Pamela Mancuso⁸, Giulia Besutti⁴, Sebastian E. Serfling⁵, Roberto Farì⁴, Matthias Frohlich⁶, Rexhep Durmo⁷, Michael Gernert⁶, Lucia Spaggiari⁴, Annibale Versari⁷, Paolo Giorgi Rossi⁸, Pierpaolo Pattacini⁴, Marc Schmalzing⁶, Carlo Salvarani¹, Thorsten Bley⁹, Francesco Muratore¹. | ¹Rheumatology Unit, AUSL IRCCS di Reggio Emilia and Università di Modena e Reggio Emilia, Italy; ²Department of Diagnostic and Interventional Neuroradiology, University Hospital Wuerzburg, Germany; ³Department of Nuclear Medicine, University of Frankfurt, Germany; ⁴Department of Radiology, AUSL IRCCS di Reggio Emilia, Italy; ⁵Department of Nuclear Medicine, University Hospital Wuerzburg, Germany; ⁶Rheumatology and Clinical Immunology, Department of Internal Medicine II, University Hospital Wuerzburg, Germany; ⁷Nuclear Medicine Unit, AUSL IRCCS di Reggio Emilia, Italy; ⁸Epidemiology Unit, AUSL-IRCCS di Reggio Emilia, Italy; ⁹Department of Diagnostic and Interventional Radiology, University Hospital Wuerzburg, Germany

Società Italiana di Reumatologia

DOI https://doi.org/10.4081/reumatismo.2025.1999
- 335 abstract views
PO:01:001 | Clinical and histopathological features of refractory psoriatic arthritis undergoing ultrasound-guided synovial biopsy: comparison between non-inflammatory and persistent inflammatory profiles

Marianna Tamussin¹, Carlo Garaffoni¹, Maria Capita¹, Serena Ceccato¹, Giovanni Lanza², Mariangela Salvato³, Kiren Khalid³, Francesca Frizzera³, Lorenzo Di Luozzo³, Annalisa Angelini⁴, Roberta Ramonda³, Alessandra Bortoluzzi¹, Andrea Doria³, Marcello Govoni¹, Alessadro Giollo³, Ettore Silvagni¹ | ¹Rheumatology Unit, Department of Medical Sciences, University of Ferrara and Azienda Ospedaliero-Universitaria S. Anna Ferrara, Italy; ²Pathology Unit, Department of Translational Medicine, University of Ferrara, Ferrara Ferrara, Italy; ³Rheumatology Unit, Department of Medicine , DIMED, University of Padua Padova, Italy; ⁴Cardiovascular Pathology, Department of Cardiac, Thoracic, Vascular Sciences and Pulic Health, University of Padua, Padova, Italy

Società Italiana di Reumatologia

DOI https://doi.org/10.4081/reumatismo.2025.2281
- 116 abstract views
PO:01:003 | Sex-based differences in 2 years treatment outcomes with b/ts-DMARDs in psoriatic arthritis: from real-world evidence to predictive modeling from the Gruppo Italiano Studio Early Arthritis (GISEA) prospective registry

Simone Perniola¹, Florenzo Iannone¹, Francesco Paolo Cantatore², Angelo Semeraro³, Leonardo Santo⁴, Roberto Gorla⁵, Alberto Cauli⁶, Roberto Felice Caporali⁷, Bruno Frediani⁸, Rosario Foti⁹, Fabrizio Conti¹⁰, Marco Sebastiani¹¹, Maria Sole Chimenti¹², Roberta Ramonda¹³, Fabiola Atzeni¹⁴, Maurizio Rossini¹⁵, Serena Bugatti¹⁶, Serena Guiducci¹⁷, Giovanni Lapadula¹, Gianfranco Ferraccioli¹⁸, Francesca Romana Spinelli¹⁰, Elisa Gremese¹⁹. | ¹Rheumatology Unit, DiMePReJ, University of Bari, Bari; ²Rheumatology Unit, Department of Medical and Surgical Sciences, Azienda Ospedaliero-Universitaria Policlinico Riuniti, Foggia; ³Rheumatology Unit, Martina Franca Hospital; ⁴Rheumatology Unit, ASL BT, P.O. Barletta; ⁵Rheumatology and Clinical Immunology Unit, ASST Spedali Civili of Brescia; ⁶Rheumatology Unit, Department of Medical Science and Public Health, University of Cagliari, Monserrato (CA); ⁷Rheumatology Unit, Dipartimento di Reumatologia e Scienze Mediche, ASST PINI-CTO, University of Milano, Milano; ⁸Rheumatology Unit, Azienda Ospedaliero Universitaria Senese, Siena; ⁹Rheumatology Unit, A.O.U. Policlinico S. Marco, Catania; ¹⁰Rheumatology Unit, Department of Clinical Internal, Anesthesiologic and CV Sciences, Sapienza University of Rome, Roma; ¹¹Rheumatology Unit, AUSL Piacenza, University of Parma, Parma; ¹²Rheumatology, Department of Systems Medicine, University of Rome Tor Vergata, Roma; ¹³Rheumatology Unit, DIMED, University of Padua, Padova; ¹⁴Rheumatology Unit, Department of Experimental and Internal Medicine, University of Messina, Messina; ¹⁵Rheumatology Unit, Department of Medicine, University of Verona, Verona; ¹⁶Division of Rheumatology, Dept. of Internal Medicine and Therapy, Fondazione IRCCS Policlinico S. Matteo, University of Pavia, Pavia; ¹⁷Division of Rheumatology, Department of Experimental and Clinical Medicine, University of Firenze, Firenze; ¹⁸Department of Medicine, Catholic University of the Sacred Heart, Fondazione Policlinico Gemelli IRCCS, Roma; ¹⁹Rheumatology and Clinical Immunology, IRCCS Humanitas Research Hospital, Humanitas University, Rozzano (MI), Italy

Società Italiana di Reumatologia

DOI https://doi.org/10.4081/reumatismo.2025.2000
- 379 abstract views
PO:01:004 | Real-world retention of IL-17 inhibitors in psoriatic arthritis: impact of prior IL-17 exposure across multiple treatment lines in the “BIRRA” multicentre cohort

Valentino Paci¹, Alarico Ariani², Eleonora Celletti³, Alberto Lo Gullo⁴, Camilla Mazzanti⁵, Valeria Nucera⁶, Natalia Mansueto⁷, Rosalba Caccavale⁸, Patrizia Del Medico⁹, Antonella Farina¹⁰, Palma Scolieri¹¹, Cecilia Giampietro¹², Olga Addimanda¹³, Riccardo Bixio¹⁴, Maddalena Larosa¹⁵, Viviana Ravagnani¹⁶, Federica Lumetti¹⁷, Aldo Biagio Molica Colella¹⁷, Elena Bravi¹⁷, Rosetta Vitetta¹⁷, Bernd Raffeiner¹⁷, Gilda Sandri¹⁸, Rosario Foti¹⁹, Simone Parisi²⁰, Michele Maria Luchetti Gentiloni¹, Gianluca Moroncini¹. | ¹Clinical Medicine, Department of Clinical and Molecular Sciences, Marche Polytechnic University, AOU delle Marche, Ancona, Italy; ²Internal Medicine and Rheumatology Unit, University Hospital of Parma, Parma, Italy; ³Rheumatology Unit, Clinica Medica Institute, Ospedale SS. Annunziata di Chieti, G.d'Annunzio University of Chieti, Chieti, Italy; ⁴Rheumatology Unit, ARNAS Garibaldi di Catania, Catania, Italy; ⁵Center for the Diagnosis and Therapy of Autoimmune Rheumagological Diseases, Ospedale Santa Rosa, ASL Viterbo Viterbo Italy; ⁶Rheumatology Outpatient Unit, ASL Novara, Novara, Italy; ⁷Ambulatori di Reumatologia ASL1 Liguria, Imperia Hospitall Imperia Italy; ⁸Department of Clinical, Anesthesiological and Cardiovascular Sciences, Sapienza University of Rome, Polo Pontino, Roma, Italy; ⁹Rheumatology outpatient clinic - Internal Medicine Unit, Civitanova Marche Hospital, Civitanova Marche, Italy; ¹⁰Internal Medicine Unit, Rheumatology outpatient clinic, Ospedale A. Murri di Fermo, Fermo, Italy; ¹¹Department of Medical Specialties, Nuovo Regina Margherita Hospital, Rome, Roma, Italy; ¹²Rheumatology Outpatient Clinic, Azienda ULSS 6 Euganea, Padova, Padova, Italy; ¹³Rheumatology Unit, Azienda Unità Sanitaria Locale di Bologna -- Policlinico S.Orsola- AOU di Bologna, Bologna, Italy; ¹⁴Rheumatology Unit, IRCCS Sacro Cuore Don Calabria Hospital, Negrar di Valpolicella, Verona, Italy; ¹⁵Division of Rheumatology - Medical Specialties Department, Ospedale La Colletta-Azienda Sanitaria Locale 3, Genova, Italy; ¹⁶Rheumatology Unit, Santa Chiara Hospital APSS Trento Italy; ¹⁷BIRRA - BIologic Retention Rate in chronic Arthritis - study group, Parma, Italy; ¹⁸Rheumatology Unit, University of Modena and Reggio Emilia, Modena, Italy; ¹⁹Rheumatology Unit, Policlinico San Marco Hospital, Catania, Italy; ²⁰Rheumatology Department, Azienda Ospedaliera Universitaria Città della Salute e della Scienza di Torino, Torino, Italy.

Società Italiana di Reumatologia

DOI https://doi.org/10.4081/reumatismo.2025.2001
- 420 abstract views
PO:01:005 | Exploring the relationship between alexithymia, pain perception, and disease burden in a cohort of patients with psoriatic arthritis

Michelina Turri¹, Eugenio Capparelli¹, Sergio Del Vescovo², Maria Iacovantuono¹, Benedetta Monosi¹, Giulia Mori¹, Ilaria Cristiano¹, Paola Conigliaro¹, Elisabetta Greco¹, Giuseppe Lopalco², Maria Sole Chimenti¹. | ¹Reumatologia, Allergologia e Immunologia Clinica, Dipartimento di Medicina dei Sistemi, Università di, Roma, Tor Vergata, Roma, Italy; ²Dipartimento di Medicina di Precisione e Rigenerativa e Area Ionica ^DiMePRe-J, Università di Bari, Bari, Italy.

Società Italiana di Reumatologia

DOI https://doi.org/10.4081/reumatismo.2025.2002
- 321 abstract views
PO:01:006 | Increased risk of cancer recurrence or mortality associated with DMARDs?

Laura Scagnellato¹, Giacomo Cozzi¹, Mariagrazia Lorenzin¹, Mariangela Salvato¹, Alessandro Giollo¹, Bernd Raffeiner¹, Antonia Calligaro¹, Teresa Del Ross¹, Sara Bindoli¹, Margherita Zen¹, Paolo Sfriso¹, Andrea Doria¹, Roberta Ramonda¹. | ¹UOC Reumatologia, Dipartimento di Medicina dei Sistemi DIMED, Ospedale Università di Padova, Padova, Italy.

Società Italiana di Reumatologia

DOI https://doi.org/10.4081/reumatismo.2025.2003
- 360 abstract views
PO:01:007 | Modulation of cellular senescence in psoriatic arthritis: exploring the potential impact of b/tsDMARDs treatment on telomere length, mtDNA copy number, and oxidative damage

Eneida Cela¹, Giada De Benedittis², Arianna D'Antonio¹, Andrea Latini³, Chiara Morgante², Cinzia Cicacci³, Paola Conigliaro¹, Mauro Fatica¹, Giulia Mori¹, Giuseppe Novelli², Paola Borgiani², Maria Sole Chimenti¹. | ¹Rheumatology, Allergology and Clinical Immunology, Department of System Medicine, University of Rome Tor Vergata, Rome, Italy; ²Department of Biomedicine and Prevention, Section of Genetics, University of Rome Tor Vergata, Rome, Italy; ³UniCamillus Saint Camillus International University of Health Sciences, Rome, Italy.

Società Italiana di Reumatologia

DOI https://doi.org/10.4081/reumatismo.2025.2004
- 317 abstract views
PO:01:008 | Active sacroiliitis at magnetic resonance enterography increases the risk of axial spondyloarthritis in Crohn’s disease patients, while greater age and disease duration are protective factors: a monocentric retrospective cohort study

Gabriele Amati¹, Gilda Sandri^1|2, Giovanni Ciancio², Benedetta Bongiovanni^1|2, Martina Orlandi^1|2, Ottavio Secchi^1|2, Davide Vaccari³, Annarita Pecchi⁴, Angela Bertani⁵, Maddalena Pecchini⁵, Pietro Torricelli⁴, Antonio Colecchia⁵, Dilia Giuggioli^1|2. | ¹Struttura Complessa di Reumatologia, Azienda Ospedaliero-Universitaria Policlinico di Modena, Modena, Italy; ²Cattedra di Reumatologia, Università degli studi di Modena e Reggio Emilia, Modena, Italy; ³Unità Operativa di Radiologia, Ospedale di Pavullo, AUSL di Modena, Modena, Italy; ⁴Struttura Complessa di Radiologia, Azienda Ospedaliero-Universitaria Policlinico di Modena, Modena, Italy; ⁵Struttura Complessa di Gastroenterologia, Azienda Ospedaliero-Universitaria Policlinico di Modena, Modena, Italy.

Società Italiana di Reumatologia

DOI https://doi.org/10.4081/reumatismo.2025.2005
- 346 abstract views
PO:01:010 | Survival of second-line treatment with TNF inhibitors vs. IL-23 inhibitors after failure of a first TNF inhibitor: a real-life observational study from the Italian multicenter BIRRA cohort in patients with psoriatic arthritis

Francesca Ometto¹, Olga Addimanda², Bernd Raffeiner³, Alberto Lo Gullo⁴, Elisa Visalli⁵, Eleonora Celletti⁶, Antonella Farina⁷, Maddalena Larosa⁸, Romina Andracco⁹, Marino Paroli¹⁰, Patrizia Del Medico¹¹, Aldo Biagio Molica Collella¹², Federica Lumetti¹³, Gilda Sandri¹⁴, Marta Priora¹⁵, Aurora Ianiello¹⁶, Elena Bravi¹⁷, Alessandra Bezzi¹⁸, Palma Scolieri¹⁹, Simone Parisi²⁰, Viviana Ravagnani²⁰, Rosetta Vitetta²⁰, Luca Idolazzi²⁰, Riccardo Bixio²⁰, Gianluca Santoboni²⁰, Francesco Girelli²⁰, Alarico Ariani²⁰ | ¹Azienda ULSS 6 Euganea, Padova; ²UOC Interaziendale di Medicina Interna ad Indirizzo Reumatologico, AUSL BO - IRCCS AOU Bologna; ³Unità di Reumatologia, Teaching Hospital of the Paracelsius Medical University, Central Hospital of Bolzano (ASAA-SABES) Bolzano; ⁴UOD Reumatologia, ARNAS Garibaldi Catania; ⁵UO Reumatologia, Policlinico San Marco Hospital Catania; ⁶UOS Reumatologia, Ospedale SS. Annunziata, Università G. d'Annunzio, Chieti; ⁷UOC Medicina Interna- Ambulatorio Reumatologico, Ospedale A. Murri, Fermo; ⁸S.C. Reumatologia, Dipartimento Specialità Mediche, Ospedale La Colletta-Azienda Sanitaria Locale 3 Genova; ⁹Ambulatorio Reumatologia, Ospedale di Imperia; ¹⁰Sapienza Università Polo Pontino, Latina; ¹¹Ambulatorio di Reumatologia, UO Medicina Interna, Civitanova Marche Hospital, Civitanova (MC); ¹²UOSD di Reumatologia, Azienda Ospedaliera Papardo Messina; ¹³Unità di Reumatologia, Azienda USL di Modena e Ospedale Universitario Policlinico di Modena; ¹⁴Unità di Reumatologia, Università di Modena e Reggio Emilia Modena; ¹⁵Ambulatorio e Day Hospital di Reumatologia, ASL CN1, Mondovì (CN); ¹⁶Poliambulatorio specialistico di reumatologia e Day Hospital multidisciplinare di area Medica, ASL Novara; ¹⁷UOSD Reumatologia, Ospedale G. Da Saliceto, Piacenza; ¹⁸UO Medicina Interna e Reumatologia, SS Reumatologia, ASL Romagna, Rimini; ¹⁹UOC Medicina Interna e Reumatologia, Ospedale Nuovo Regina Margherita, Roma; ²⁰Gruppo BIRRA Italy

Società Italiana di Reumatologia

DOI https://doi.org/10.4081/reumatismo.2025.2122
- 432 abstract views
PO:01:011 | Achievement of Remission Defined by Absence of Objective Signs of Inflammation Versus ASDAS ID in Patients with Active Axial Spondyloarthritis Treated with Bimekizumab: 52-Week Results from Two Phase 3 Studies

Lianne S Gensler¹, Helena Marzo-Ortega², Vanessa Taieb³, Diana Voiniciuc⁴, Alexander Marten⁵, George Stojan⁶, Mindy Kim⁶, Paolo Marsico⁷, Martin Rudwaleit⁸ | ¹Department of Medicine/Rheumatology, University of California San Francisco, USA; ²NIHR Leeds Biomedical Research Centre, University of Leeds Leeds, United Kingdom; ³UCB Colombes, France; ⁴UCB Slough, United Kingdom; ⁵UCB Monheim am Rhein Germany; ⁶UCB Atlanta, USA; ⁷UCB Milan, Italy; ⁸University of Bielefeld, Klinikum Bielefeld Bielefeld Germany

Società Italiana di Reumatologia

DOI https://doi.org/10.4081/reumatismo.2025.2282
- 121 abstract views
PO:01:014 | Differential inflammatory responses of CD14+ and CD14– synoviocytes in psoriatic arthritis: implications for pathogenesis and targeted therapies

Monia Maccaferri¹, Monica Montanari², Francesco Zambianchi^3|4, Carlo Salvarani^1|5, Elisa Pignatti^1|4 | ¹Dipartimento CHIMOMO; ²Dipartimento di Scienze e Vita; ³Dipartimento SMECHIMAI Università di Modena e Reggio Emilia; ⁴Azienda Ospedaliero Universitaria di Modena; ⁵Struttura Complessa di Reumatologia, Azienda Unità Sanitaria Locale di Reggio Emilia-IRCCS, Italy

Società Italiana di Reumatologia

DOI https://doi.org/10.4081/reumatismo.2025.2123
- 298 abstract views
PO:01:015 | Assessment of the impact of the co-occurrence of psoriasis on the clinical and therapeutic pattern of a single-centre cohort of patients with spondyloarthritis associated with chronic inflammatory bowel disease

Andrea Pace¹, Marcella Falconi¹, Alberto Floris^1|2, Leonardo Sichi¹, Francesca Onnis³, Lorenzo Meli³, Raffaela Piras³, Nicola Lutzu³, Federica Olla³, Agnese Favale³, Sara Onali³, Massimo Claudio Fantini³, Matteo Piga^1|2, Alberto Cauli^1|2. | ¹SC Reumatologia, Dipartimento di Scienze Mediche e Salute Pubblica, Università di Cagliari, Cagliari, Italy; ²SC Reumatologia, AOU Cagliari, Cagliari, Italy; ³SC Gastroenterologia, AOU Cagliari, Cagliari, Italy.

Società Italiana di Reumatologia

DOI https://doi.org/10.4081/reumatismo.2025.2006
- 365 abstract views
PO:01:015 | Evaluation of the impact of concomitant psoriasis on the clinical and therapeutic pattern of a monocentric cohort of patients affected by spondyloarthritis associated with inflammatory bowel diseases

Andrea Pace¹, Marcella Falconi¹, Alberto Floris^1|2, Leonardo Sichi¹, Francesca Onnis³, Lorenzo Meli³, Raffaela Piras³, Nicola Lutzu³, Federica Olla³, Agnese Favale³, Sara Onali³, Massimo Claudio Fantini³, Matteo Piga^1|2, Alberto Cauli^1|2 | ¹SC Reumatologia, Dipartimento di Scienze Mediche e Salute Pubblica, Università di Cagliari; ²SC Reumatologia, AOU Cagliari; ³SC Gastroenterologia, AOU Cagliari, Italy

Società Italiana di Reumatologia

DOI https://doi.org/10.4081/reumatismo.2025.2124
- 278 abstract views
PO:02:016 | Real-world evidence of upadacitinib over two years in Italian patients with axial spondyloarthritis

Mariagrazia Lorenzin¹, Giacomo Cozzi¹, Stefano Gentileschi², Michele Maria Luchetti Gentiloni³, Antonio Carletto⁴, Maria Sole Chimenti⁵, Maria Manara⁶, Luca Quartuccio⁷, Rosario Foti⁸, Salvatore D'Angelo⁹, Ariela Hoxha¹⁰, Carlo Selmi¹¹, Bernd Raffeiner¹², Alessandro Giollo¹, Alberto Cauli¹³, Carlo Salvarani¹⁴, Fabiola Atzeni¹⁵, Roberta Ramonda¹, Sir Study Group Spa E Psa Antonio Spadaro¹⁶. | ¹Rheumatology Unit, Department of Medicine DIMED, University of Padova, Padova, Italy; ²Rheumatology Unit, Department of Medicine, Surgery and Neurosciences, University of Siena, Siena, Italy; ³Clinica Medica, Ospedali Riuniti Ancona University Hospital, Ancona; Department of Clinical and Molecular Sciences, Ancona, Italy; ⁴Rheumatology Unit, Department of Medicine, AOUI University of Verona, Verona, Italy; ⁵Rheumatology, allergology and clinical Immunology, Department of Systems Medicine, University of Rome Tor Vergata, Roma, Italy; ⁶Humanitas San Pio X, Milano, Italy; ⁷University of Udine, Academic Hospital Santa Maria della Misericordia, Udine, Italy; ⁸Rheumatology Unit, A.O.U. Policlinico S. Marco, Catania, Italy; ⁹Rheumatology Department of Lucania, San Carlo Hospital of Potenza and Madonna delle Grazie Hospital of Matera, Potenza, Italy; ¹⁰Internal Medicine Unit, Thrombotic and Hemorrhagic Center, Department of Medicine-DIMED, University of Padua, Padova, Italy; ¹¹Department of Rheumatology and Clinical Immunology, IRCCS Humanitas Research Hospital, Rozzano, Milano, Italy; ¹²Department of Rheumatology, Teaching Hospital of the Paracelsius Medical Hospital of Bolzano ASAA-SABES, Bolzano, Italy; ¹³Rheumatology Unit, Department of Medical Sciences, AOU and University of Cagliari, Monserrato, Cagliari, Italy; ¹⁴Department of Rheumatology, Azienda USL-IRCCS di Reggio Emilia and Università di Modena and Reggio Emilia, Reggio Emilia, Italy; ¹⁵Rheumatology Unit, University of Messina, Messina, Italy; ¹⁶Società Italiana di Reumatologia, Milano, Italy.

Società Italiana di Reumatologia

DOI https://doi.org/10.4081/reumatismo.2025.2007
- 352 abstract views
PO:02:017 | Difficult-to-treat psoriatic arthritis: clinical and ultrasonographic predictors in a real-life cohort

Federico Favaro¹, Elisa Bellis¹, Claudio Cruciani¹, Gloria Crepaldi¹, Valeria Data¹, Claudia Garulli¹, Claudia Lomater¹, Elena Marucco¹, Marta Saracco¹, Mariele Gatto¹, Annamaria Iagnocco¹. | ¹Academic Rheumatology Centre, Departement of Clinical and Biological Sciences, University of Turin, AO Mauriziano, Torino, Italy.

Società Italiana di Reumatologia

DOI https://doi.org/10.4081/reumatismo.2025.2008
- 304 abstract views
PO:02:018 | After-SECs: clinical predictors of secukinumab retention in psoriatic arthritis patients with inadequate response to anti-tumor necrosis factor therapy

Francesco Cristiano¹, Davide Gaspare Patti¹, Valentina Boni¹, Stefano Di Murro¹, Cesare Gavotti¹, Roberta Masnata¹, Giulia Calabrese², Gerlando Natalello², Giusy Peluso², Augusta Ortolan^1|2, Enrico De Lorenzis^1|2, Maria Antonietta D'Agostino^1|2. | ¹Università Cattolica del Sacro Cuore, Roma, Italy; ²Divisione di Reumatologia ed Immunologia clinica, Fondazione Policlinico Universitario A. Gemelli IRCCS, Roma, Italy.

Società Italiana di Reumatologia

DOI https://doi.org/10.4081/reumatismo.2025.2009
- 358 abstract views
PO:02:019 | Incidence of Spondyloarthritis in a Cohort of Italian patients presenting with Acute Non-granulomatous Anterior Uveitis during a five-years follow-up period

Alessandra Rai¹, Niccolò Possemato^1|2, Giorgia Citriniti², Filippo Crescentiini², Marianna Oliva², Elena Bolletta³, Pietro Gentile³, Luca De Simone³, Fabrizio Gozzi³, Luca Cimino^1|3, Pierluigi Macchioni², Carlo Salvarani^1|2 | ¹Università di Modena e Reggio Emilia Modena, Italy; ²Unità di Reumatologia, Azienda USL-IRCCS Reggio Emilia, Reggio Emilia, Italy; ³Unità di Immunologia Oculare, Azienda USL-IRCCS Reggio Emilia, Reggio Emilia, Italy

Società Italiana di Reumatologia

DOI https://doi.org/10.4081/reumatismo.2025.2283
- 114 abstract views
PO:02:021 | Sustained Improvements with Bimekizumab in Pain, Morning Stiffness, Fatigue, Physical Function and Health-Related Quality of Life in Patients with Axial Spondyloarthritis: 3-Year Results from Two Phase 3 Studies

Victoria Navarro-Compán¹, Uta Kiltz^2|3, Philip J Mease⁴, Maureen Dubreuil⁵, Karl Gaffney⁶, Atul Deodhar⁷, Christine De La Loge⁸, Diana Voiniciuc⁹, Jason Coarse¹⁰, Ilaria Spadafora¹¹, Helena Marzo-Ortega¹² | ¹La Paz University Hospital, IdiPaz, Department of Rheumatology Madrid Spain; ²Ruhr-University Bochum Bochum Germany; ³Rheumazentrum Ruhrgebiet Herne, Germany; ⁴Department of Rheumatology, Swedish Medical Center and Providence St. Joseph Health and University of Washington Seattle, USA; ⁵Boston University School of Medicine, Department of Rheumatology Boston, USA; ⁶Norfolk and Norwich University Hospital NHS Trust, Department of Rheumatology Norfolk, United Kingdom; ⁷Oregon Health and Science University, Division of Arthritis and Rheumatic Diseases Portland, USA; ⁸UCB Brussels, Belgium; ⁹UCB Slough, United Kingdom; ¹⁰UCB Morrisville, USA; ¹¹UCB Milan, Italy; ¹²NIHR Leeds Biomedical Research Centre, University of Leeds Leeds, United Kingdom

Società Italiana di Reumatologia

DOI https://doi.org/10.4081/reumatismo.2025.2284
- 129 abstract views
PO:02:022 | Bimekizumab Maintained Stringent Clinical Responses over 2 Years in Patients with Axial Spondyloarthritis: Results from Two Phase 3 Studies

Fabian Proft¹, Désirée Van Der Heijde², Sergio Schwartzman^3|4|5, Joerg Ermann⁶, Alexander Marten⁷, Ute Massow⁷, George Stojan⁸, Vanessa Taieb⁹, Diana Voiniciuc¹⁰, Astrid Van Tubergen¹¹, Victoria Navarro-Compán¹², Simone Angioni¹³, Xenofon Baraliakos¹⁴ | ¹Charité-Universitätsmedizin Berlin; Freie Universität Berlin and Humboldt-Universität zu Berlin, Berlin, Germany; ²Department of Rheumatology, Leiden University Medical Center Leiden, The Netherlands; ³Weill Cornell Medical Center New York, USA; ⁴New York Presbyterian Hospital New York, USA; ⁵Hospital for Special Surgery New York, USA; ⁶Division of Rheumatology, Inflammation and Immunity, Brigham and Women's Hospital and Harvard Medical School Boston, USA; ⁷UCB Monheim am Rhein Germany; ⁸UCB Atlanta, USA; ⁹UCB Colombes, France; ¹⁰UCB Slough, United Kingdom; ¹¹Department of Medicine, Division of Rheumatology, Maastricht University Medical Center Maastricht, The Netherlands; ¹²Department of Rheumatology, La Paz University Hospital, IdiPaz Madrid, Spain; ¹³UCB Milan, Italy; ¹⁴Rheumazentrum Ruhrgebiet Herne, Ruhr-University Bochum, Germany

Società Italiana di Reumatologia

DOI https://doi.org/10.4081/reumatismo.2025.2285
- 144 abstract views
PO:02:023 | Monocentric analysis of systemic glucocorticoids in PsA: the art of balancing prescriptive appropriateness and risk factor management

Chiara Crotti^{1 2}, Gilberto Cincinelli¹, Giorgia Trignani¹³, Luca Ingrao¹³, Miriam Perino¹³, Roberto Caporali¹³ | ¹Dipartimento di Reumatologia e Scienze Mediche - UOC Clinica Reumatologica, ASST Pini-CTO, Milano; ²Dipartimento di Reumatologia e Scienze Mediche - UOC Osteoporosi e Malattie Metaboliche dell Osso - ASST Pini-CTO, Milano; ³Dipartimento di Scienze Cliniche e di Comunità - Università degli Studi di Milano, Italy

Società Italiana di Reumatologia

DOI https://doi.org/10.4081/reumatismo.2025.2125
- 309 abstract views
PO:02:024 | Development of anti-drug antibodies in patients with peripheral and/or axial spondyloarthritis treated with infliximab or adalimumab: a monocentric cross-sectional study

Gabriele Amati¹, Gilda Sandri^1|2, Alessandra Melegari³, Benedetta Bongiovanni^1|2, Giovanni Ciancio², Martina Orlandi^1|2, Ottavio Secchi¹, Dilia Giuggioli^1|2 | ¹Struttura complessa di Reumatologia, Azienda Ospedaliero-Universitaria Policlinico di Modena; ²Cattedra di Reumatologia, Università degli studi di Modena e Reggio Emilia; ³Dipartimento di medicina di laboratorio, Ospedale di Baggiovara, AUSL di Modena, Italy

Società Italiana di Reumatologia

DOI https://doi.org/10.4081/reumatismo.2025.2126
- 360 abstract views
PO:02:025 | Real-World Comparative Effectiveness of Upadacitinib in Psoriatic Arthritis: Evaluation of Switching to Upadacitinib Versus Tumor Necrosis Factor Inhibitors or Interleukin-17 Inhibitors After First-Line Tumor Necrosis Factor Inhibitors

Valentina Carlini¹, Philip Mease², William Tillett³, Xiaolan Ye⁴, Christopher Saffore⁴, Molly Edwards⁵, Isabel Truman⁵, Sophie Barlow⁵, Jayne Stigler⁴, Bhumik Parikh⁴, Daniel Aletaha⁶ | ¹Abbvie srl Roma, Italy; ²University of Washington School of Medicine Seattle, United States Minor Outlying Islands; ³Department of Rheumatology, Royal National Hospital for Rheumatic Diseases Bath, United Kingdom; ⁴Abbvie Inc. North Chicago, United States Minor Outlying Islands; ⁵Adelphi Real World Bollington, United Kingdom; ⁶Division of Rheumatology, Department of Medicine, Medical University of Vienna, Vienna, Austria

Società Italiana di Reumatologia

DOI https://doi.org/10.4081/reumatismo.2025.2286
- 179 abstract views
PO:02:027 | Fast food, slow damage: ultra-processed foods, Western diet and inflammatory arthritis. A systematic scoping review

Gianluca Poncina¹, Federica Gardin², Giacomo Cozzi¹, Laura Scagnellato¹, Mariagrazia Lorenzin¹, Stefano Rizzetto¹, Caterina Robusto¹, Francesca Oliviero¹, Valérie Tikhonoff², Roberta Ramonda¹. | ¹Rheumatology Unit, Department of Medicine-DIMED, University - Padova University Hospital, Padova, Italy; ²Department of Medicine-DIMED, University - Padova University Hospital, Padova, Italy.

Società Italiana di Reumatologia

DOI https://doi.org/10.4081/reumatismo.2025.2010
- 671 abstract views
PO:02:028 | Dal Pain Catastrophizing al Distress Psicologico Multidimensionale: esplorando la complessità dell’Artrite Psoriasica Difficult- to-Treat

Francesca Saracino¹, Damiano Currado^1|2, Francesco De Vincenzo³, Francesca Trunfio¹, Annalisa Marino¹, Lyubomyra Kun¹, Erika Corberi¹, Ludovica Lamberti¹, Leonardo Frascà¹, Onorina Berardicurti^1|2, Marta Gatti¹, Marta Vomero^1|2, Roberto Giacomelli^1|2, Luca Navarini^1|2 | ¹Reumatologia e Immunologia Clinica, Dipartimento di Medicina, Università Campus Bio-Medico di Roma, Facoltà di Medicina Roma, Italy; ²Sezione Clinica e di Ricerca di Reumatologia e Immunologia Clinica, Fondazione Policlinico Campus Bio-Medico Roma, Italy; ³Dipartimento di Scienze Umane, Università Europea di Roma Roma, Italy

Società Italiana di Reumatologia

DOI https://doi.org/10.4081/reumatismo.2025.2287
- 116 abstract views
PO:02:030 | Retention Rate of Non-anti-TNF Therapies and primary failure in monocentric cohort of patients with Psoriatic Arthritis

Alba Chiara Pozzi¹, Sofia Barezzani², Andrea Galli², Cesare Tomasi¹, Micol Frassi¹, Ilaria Cavazzana¹, Franco Franceschini¹ | ¹Rheumatology and Clinical Immunology Unit ERN-ReCONNECT, ASST Spedali Civili, University of Brescia Brescia, Italy; ²Facoltà di Medicina e Chirurgia, University of Brescia Brescia, Italy

Società Italiana di Reumatologia

DOI https://doi.org/10.4081/reumatismo.2025.2288
- 159 abstract views
PO:03:033 | Low Uveitis Rates in Patients with Axial Spondyloarthritis or Psoriatic Arthritis Treated with Bimekizumab: Long-Term Results from Phase 2b/3 Trials

Irene E Van Der Horst-Bruinsma¹, Matthew A Brown², Floris A Van Gaalen³, Nigil Haroon⁴, Lianne S Gensler⁵, Alexander Marten⁶, Myriam Manente⁷, George Stojan⁸, Thomas Vaux⁹, Katy White⁹, Atul Deodhar¹⁰, Nicola Boffini¹¹, Martin Rudwaleit¹² | ¹Department of Rheumatology, Radboud University Medical Centre Nijmegen, The Netherlands; ²Genomics England London, United Kingdom; ³Department of Rheumatology, Leiden University Medical Center Leiden, The Netherlands; ⁴Department of Medicine/Rheumatology, University Health Network, Schroeder Arthritis Institute, University of Toronto Toronto, Canada; ⁵Department of Medicine/Rheumatology, University of California San Francisco, USA; ⁶UCB Monheim am Rhein Germany; ⁷UCB Braine-lAlleud, Belgium; ⁸UCB Atlanta, USA; ⁹UCB Slough, United Kingdom; ¹⁰Division of Arthritis and Rheumatic Diseases, Oregon Health and Science University Portland, USA; ¹¹IRCCS Ospedale San Raffaele Milan, Italy; ¹²Klinikum Bielefeld, University of Bielefeld, Bielefeld, Germany

Società Italiana di Reumatologia

DOI https://doi.org/10.4081/reumatismo.2025.2289
- 163 abstract views
PO:03:034 | Inhibition of Radiographic Progression with Bimekizumab Treatment Observed in bDMARD-Naïve Patients with Active Psoriatic Arthritis at 2 Years: Results from a Phase 3 Study and its Open-Label Extension

Laura C Coates¹, M Elaine Husni², Mitsumasa Kishimoto³, Proton Rahman⁴, Philipp Sewerin⁵, Enrique R Soriano⁶, Barbara Ink⁷, Rajan Bajracharya⁷, Jason Coarse⁸, Philip J Mease⁹, Emanuela Mazzola¹⁰, Peter Nash¹¹ | ¹NDORMS, University of Oxford and Oxford Biomedical Research Centre, Oxford University Hospitals NHS Trust Oxford, United Kingdom; ²Department of Rheumatic and Immunologic Diseases, Cleveland Clinic Cleveland, USA; ³Department of Nephrology and Rheumatology, Kyorin University School of Medicine Tokyo, Japan; ⁴Division of Rheumatology, Craig L. Dobbin Genetics Research Centre, Memorial University of Newfoundland St. Johns, Canada; ⁵Rheumazentrum Ruhrgebiet, University Hospital of the Ruhr University Bochum Herne Germany; ⁶Hospital Italiano de Buenos Aires and University Institute Hospital Italiano de Buenos Aires Buenos Aires, Argentina; ⁷UCB Slough, United Kingdom; ⁸UCB Morrisville, USA; ⁹Department of Rheumatology, Providence-Swedish Medical Center and University of Washington Seattle, USA; ¹⁰UCB Milan, Italy; ¹¹School of Medicine, Griffith University, Brisbane, Australia

Società Italiana di Reumatologia

DOI https://doi.org/10.4081/reumatismo.2025.2290
- 230 abstract views
PO:03:035 | Biomarkers of Gut Epithelial Damage, Microbial Translocation, and Innate Immune Activation Characterize Patients with Axial Psoriatic Arthritis from Psoriasis Patients: Soluble Biomarker Analysis Insights from the ATTRACT Study

Giulia Marchionni¹, Valentino Paci¹, Silvia Svegliati¹, Raffaella Sordillo¹, Federico Fiorini¹, Melania Giannoni¹, Anna Campanati¹, Raissa Di Zio¹, Devis Benfaremo¹, Giuseppe Lopalco², Florenzo Iannone², Ennio Lubrano³, Alberto Cauli⁴, Gianluca Moroncini¹, Dennis Poddubnyy⁵, Fabian Proft⁶, Michele M Luchetti Gentiloni¹ | ¹Marche Polytechnic University and Azienda Ospedaliero-Universitaria delle Marche, Ancona, Italy; ²University of Bari, Bari, Italy; ³Molise University, Campobasso, Italy; ⁴University of Cagliari, Azienda Ospedaliero Universitaria di Cagliari, Monserrato, Italy; ⁵University of Toronto, Toronto, Canada; ⁶Charité-Universitätsmedizin, Berlino, Germany

Società Italiana di Reumatologia

DOI https://doi.org/10.4081/reumatismo.2025.2291
- 122 abstract views
PO:03:036 | Psoriatic arthritis: does pre-existing treatment with cs/bDMARDs for psoriasis influence the characteristics and outcomes of joint disease?

Ilenia Marchesini¹, Alberto Floris¹, Cristina Mugheddu², Laura Li Volsi¹, Maria Teresa Paladino¹, Roberta Origa¹, Jessica Sorgia¹, Mattia Congia¹, Elisabetta Chessa¹, Matteo Piga¹, Caterina Ferreli², Laura Atzori², Alberto Cauli¹ | ¹Unità di Reumatologia, AOU e Università di Cagliari-Monserrato; ²Unità di Dermatologia, AOU e Università di Cagliari, Italy

Società Italiana di Reumatologia

DOI https://doi.org/10.4081/reumatismo.2025.2127
- 357 abstract views
PO:03:037 | The Impact of Peripheral Joint Involvement, Pain, and Inflammatory Bowel Diseases on Drug Persistence in Axial Psoriatic Arthritis

Giuseppe Lopalco¹, Sergio Del Vescovo¹, Maria Sole Chimenti², Giuliana Guggino³, Serena Guiducci⁴, Eleonora Celletti⁵, Alberto Cauli⁶, Luca Cantarini⁷, Valentino Paci⁸, Eneida Cela², Lidia La Barbera³, Gemma Lepri⁴, Myriam Di Penta⁵, Alberto Floris⁶, Alice Agostinelli⁸, Vincenzo Venerito¹, Michele Maria Luchetti⁸, Florenzo Iannone¹ | ¹Rheumatology Unit, Department of Precision and Regenerative Medicine and Ionian Area, Bari, Italy; ²Reumatology, Allergology and Clinical Immunology University of Rome Tor Vergata, Roma, Italy; ³Department of Health Promotion Sciences, Maternal and Infant Care, Internal Medicine and Medical Specialties, Palermo, Italy; ⁴Divisions of Internal Medicine and Rheumatology AOUC, Department of Experimental and Clinical Medicine, Firenze, Italy; ⁵Rheumatology Unit, SS. Annunziata Hospital of Chieti, G. D'Annunzio, Chieti, Italy; ⁶Department of Medical Science and Public Health, Cagliari, Italy; ⁷Policlinico Le Scotte, Siena, Italy; ⁸Clinical Medicine, Dipartimento di Scienze Cliniche e Molecolari, Università Politecnica delle Marche, Ancona, Italy

Società Italiana di Reumatologia

DOI https://doi.org/10.4081/reumatismo.2025.2292
- 97 abstract views
PO:03:039 | Extraintestinal manifestations of enteropathic arthritis vary in relation to inflammatory bowel disease behaviour, localization, and extent

Bernardo D'Onofrio¹, Nicoletta Luciano^2|3, Simone Parisi¹, Maria Chiara Ditto¹, Cristina Bezzio^2|4, Enrico Fusaro¹, Alessandro Armuzzi^2|4, Carlo Selmi^2|3 | ¹Division of Rheumatology, AOU Città della Salute e della Scienza, Torino, Italy; ²Department of Biomedical Sciences, Humanitas University, Pieve Emanuele, Italy; ³Rheumatology and Clinical Immunology, IRCCS Humanitas Research Hospital, Rozzano, Italy; ⁴Inflammatory Bowel Disease Unit, IRCCS Humanitas Research Hospital, Rozzano, Italy

Società Italiana di Reumatologia

DOI https://doi.org/10.4081/reumatismo.2025.2293
- 91 abstract views
PO:03:044 | Impact of Inflammatory Bowel Disease on Clinical Phenotype and Treatment Response in Patients with Psoriatic Arthritis

Maria Morrone¹, Maria Giannotta¹, Vincenzo Venerito¹, Greta Giulia Dipietrangelo¹, Stefano Stano¹, Florenzo Iannone¹, Giuseppe Lopalco¹ | ¹Department of Precision and Regenerative Medicine and Ionian Area DiMePRe-J University of Bari, Bari, Italy

Società Italiana di Reumatologia

DOI https://doi.org/10.4081/reumatismo.2025.2294
- 132 abstract views
PO:04:046 | Achieving Early Clinical Response was Associated with Cumulative Benefits on Disease Impact up to 2 Years in Patients with Active Psoriatic Arthritis Treated with Bimekizumab

William Tillett^1|2, Joseph F Merola³, Iain B Mcinnes⁴, Kenneth B Gordon⁵, Richard B Warren⁶, Patrick Healy⁷, Jérémy Lambert⁸, Heather Edens⁹, Barbara Ink¹⁰, Paola Volpe¹¹, Laure Gossec¹² | ¹Royal National Hospital of Rheumatic Diseases Bath, United Kingdom; ²Department of Life Sciences, Centre for Therapeutic Innovation, University of Bath Bath, United Kingdom; ³Department of Dermatology and Department of Medicine, Division of Rheumatology, Utah Southwestern Medical Center Dallas, USA; ⁴College of Medical Veterinary and Life Sciences, University of Glasgow Glasgow, United Kingdom; ⁵Department of Dermatology, Medical College of Wisconsin Milwaukee, USA; ⁶Northern Care Alliance, NHS Foundation Trust and Manchester Academic Health Science Centre, University of Manchester Manchester, United Kingdom; ⁷UCB Morrisville, USA; ⁸UCB Colombes, France; ⁹UCB Smyrna, USA; ¹⁰UCB Slough, United Kingdom; ¹¹UOC Reumatologia, P.O. Spirito Santo Pescara, Italy; ¹²Sorbonne Universite and Pitie-Salpetriere Hospital Paris, France

Società Italiana di Reumatologia

DOI https://doi.org/10.4081/reumatismo.2025.2295
- 198 abstract views
PO:04:048 | Assessment of chronic and residual pain in axial spondyloarthritis in a single-center cohort of patients treated with anti-tnf agents

Valentina Fornero^1|2, Niccolò Melis¹, Emanuela Salustro¹, Mattia Congia¹, Elisabetta Chessa¹, Alberto Floris¹, Matteo Piga¹, Alberto Cauli¹ | ¹Rheumatology unit, AOU e Università di Cagliari; ²Asl Biella, Ospedale degli Infermi, Ponderano (BI), Italy

Società Italiana di Reumatologia

DOI https://doi.org/10.4081/reumatismo.2025.2128
- 316 abstract views
PO:04:050 | Cluster-Based Endotyping of Psoriatic Arthritis in a Monocentric Italian Cohort: A Real-World study

Eneida Cela¹, Arianna D'Antonio¹, Luigi Fiannacca¹, Alberto Bergamini¹, Maxime Breban², Felicie Costantino², Maria Sole Chimenti¹ | ¹Rheumatology, Allergology and Clinical Immunology, Department of System Medicine, University of Rome Tor Vergata Rome, Italy; ²Rheumatology Department, AP-HP, Ambroise-Paré Hospital Paris, France

Società Italiana di Reumatologia

DOI https://doi.org/10.4081/reumatismo.2025.2296
- 101 abstract views
PO:04:051 | Application of REMS in the assessment of fragility score and bone mineral density in axial spondyloarthritis and psoriatic arthritis with axial involvement

Silvia Valentini¹, Stefano Gentileschi¹, Pamela Bernardini², Jurgen Sota¹, Caterina Baldi¹, Sara Torracchi², Daniela Melchiorre², Sabrina Aliberti², Emilio D'Ignazio¹, Carla Caffarelli³, Luca Cantarini¹, Serena Guiducci², Bruno Frediani¹ | ¹UOC Reumatologia, Dipartimento di Scienze mediche, chirurgiche e neuroscienze, Università degli Studi di Siena; ²SOD Reumatologia, Dipartimento di Medicina Sperimentale e clinica, Università degli studi di Firenze, AOU Careggi; ³UOC Medicina Interna e della Complessità, Dipartimento di Scienze Mediche, chirurgiche e neuroscienze, Università degli Studi di Siena, Italy

Società Italiana di Reumatologia

DOI https://doi.org/10.4081/reumatismo.2025.2129
- 309 abstract views
PO:04:054 | Clinical efficacy and drug retention rate of upadacitinib in patients with axial spondyloarthritis: results from a single-center observational study

Simona Buonanno¹, Carla Gaggiano¹, Caterina Baldi¹, Marco Bardelli¹, Cristiana Barreca¹, Francesca Bellisai¹, Marta Fabbroni¹, Paolo Falsetti¹, Anna Paola Pata¹, Enrico Selvi¹, Jurgen Sota¹, Antonio Vitale¹, Luca Cantarini¹, Bruno Frediani¹, Stefano Gentileschi¹ | U.O.C. Reumatologia, Dipartimento di Scienze Mediche, Chirurgiche e Neuroscienze, Università di Siena, A.O.U. Senese, Italy

Società Italiana di Reumatologia

DOI https://doi.org/10.4081/reumatismo.2025.2130
- 314 abstract views
PO:04:056 | Willingness of patients with psoriatic arthritis to participate in pharmacological and nutritional clinical trials: a cross-sectional study

Miriam Perino^1|2, Francesca Ingegnoli^1|2, Luca Ingrao^1|2, Debora Piredu^1|2, Antonio Varvaro^1|2, Camilla Riboldi^1|2, Gilberto Cincinelli², Francesca Desiati², Martina Biggioggero², Orazio De Lucia², Silvia Casari², Maria Manara², Ennio Giulio Favalli^1|2, Roberto Caporali^1|2 | ¹Università degli Studi di Milano, Dipartimento di Scienze Cliniche e di Comunità, Milano; ²ASST G. Pini-CTO, UOC di Clinica Reumatologica, Milano, Italy

Società Italiana di Reumatologia

DOI https://doi.org/10.4081/reumatismo.2025.2131
- 325 abstract views
PO:04:061 | Higher prevalence of baseline comorbidities in patients developing difficult to treat psoriatic arthritis

Mario Ferraioli¹, Michelina Turri¹, Eneida Çela¹, Mauro Fatica¹, Paola Conigliaro¹, Elisabetta Greco¹, Alberto Bergamini¹, Maria Sole Chimenti¹. | ¹Rheumatology, Allergology and Clinical Immunology, Department of Systems Medicine, University of Rome, Tor Vergata, Rome, Italy.

Società Italiana di Reumatologia

DOI https://doi.org/10.4081/reumatismo.2025.2011
- 300 abstract views
PO:05:066 | Atypical diagnosis and manifestation of spondyloarthritis: a case report

Adele Del Giudice¹, Filippo Crescentini², Giorgia Citriniti², Luca Cimino^1|3, Carlo Salvarani^1|2 | ¹Department of Rheumatology, Università Cattolica del Sacro Cuore, Fondazione Policlinico Universitario A. Gemelli IRCCS, Roma, Italy; ²Department of Medicine, University of Melbourne at St Vincent's Hospital Melbourne, Australia; ³Department of Rheumatology, Division of Medicine, University College, London, UK

Società Italiana di Reumatologia

DOI https://doi.org/10.4081/reumatismo.2025.2132
- 322 abstract views
PO:05:069 | Risankizumab efficacy in peripheral and axial involvement: monocentric experience

Roberta Foti¹, Ylenia Dal Bosco¹, Giorgio Amato¹, Elisa Visalli¹, Francesco De Lucia¹, Gabriella Paolí¹, Rosario Foti¹. | ¹UOSD Reumatologia AOU Policlinico G. Rodolico-S. Marco, Catania, Italy.

Società Italiana di Reumatologia

DOI https://doi.org/10.4081/reumatismo.2025.2012
- 420 abstract views
PO:05:071 | Impact of age at onset on Spondyloarthritis clinical profile and quality of life: a monocentric cohort analysis

Federico Fattorini¹, Marco Di Battista¹, Lorenzo Esti¹, Cosimo Cigolini², Andrea Delle Sedie², Marta Mosca^1|2, Linda Carli¹ | ¹Rheumatology Unit, Department of Clinical and Experimental Medicine, University of Pisa, Pisa, Italy; ²Rheumatology Unit, AOUP, Pisa, Italy

Società Italiana di Reumatologia

DOI https://doi.org/10.4081/reumatismo.2025.2297
- 170 abstract views
PO:05:074 | A clinical case of a patient affected by long-standing psoriatic arthritis and multiple comorbidities treated with an anti-IL-23 therapy

Maria Letizia Currò¹, Angelo Tropea¹, Alessandra Burgio¹, Francesca Cracò¹, Antonio Pezzano¹, Federica Rapisarda¹, Antonino Palumbo¹, Valeria D'Amico¹, Fabiola Atzeni¹ | ¹Clinica Reumatologica di Udine, Dipartimento di Medicina, ASUFC, Udine, Italy

Società Italiana di Reumatologia

DOI https://doi.org/10.4081/reumatismo.2025.2133
- 308 abstract views
PO:06:078 | Is difficult-to-treat rheumatoid arthritis less severe in patients with autoantibody-negative disease? retrospective analysis from a monocentric cohort.

Bernardo D'Onofrio¹, Maria Chiara Ditto¹, Francesco Ghellere¹, Giacomo Tanti¹, Salvatore Panaro¹, Enrico Fusaro¹, Simone Parisi¹. | ¹AOU Città della Salute e della Scienza, Torino, Italy.

Società Italiana di Reumatologia

DOI https://doi.org/10.4081/reumatismo.2025.2013
- 282 abstract views
PO:06:079 | Weighing the burden: how body mass index shapes clinical outcomes in rheumatoid arthritis. Insights from a large Italian cohort

Marco Capodiferro¹, Marco Fornaro¹, Gian Luca Erre², Matteo Piga³, Elena Bartoloni Bocci⁴, Andreina Manfredi⁵, Ennio Giulio Favalli⁶, Maria Sole Chimenti⁷, Serena Guiducci⁸, Eleonora Celletti⁹, Addolorata Corrado¹⁰, Alessandro Giollo¹¹, Simone Parisi¹², Ivan Giovannini¹³, Elisa Gremese¹⁴, Garifallia Sakellariou¹⁵, Ombretta Viapiana¹⁶, Fabiola Atzeni¹⁷, Francesca Romana Spinelli¹⁸, Fabio Cacciapaglia^1|19. | ¹Rheumatology Unit, Department of Precision and Regenerative Medicine and Ionian Area DiMePRe-J University of Bari, Bari, Italy; ²Dipartimento di Scienze Mediche, Chirurgiche e Sperimentali, Università degli Studi di Sassari, Sassari, Italy; ³Rheumatology Unit, AOU Cagliari, Department of Medical Sciences and Public Health, University of Cagliari, Cagliari, Italy; ⁴Rheumatology Unit, Department of Medicine and Surgery, University of Perugia, Perugia, Italy; ⁵Rheumatology Unit, Azienda Ospedaliera Universitaria Policlinico of Modena, Modena, Italy; ⁶Dpt of Rheumatology, G. Pini Institute, Milano, Italy; ⁷Rheumatology, Allergology and Clinical Immunology, Department of Systems Medicine, University of Rome Tor Vergata, Rome, Italy; ⁸Department of Experimental and Clinical Medicine, Division of Rheumatology, University of Florence, Firenze, Italy; ⁹Rheumatology Unit, SS Annunziata Hospital, Chieti, Italy; ¹⁰Rheumatology Unit, Department of Medical and Surgical Sciences, University of Foggia, Foggia, Italy; ¹¹Rheumatology Unit, Department of Medicine, University of Padova Hospital Trust, Padova, Italy; ¹²Rheumatology Department, A.O.U. Città della Salute e della Scienza, Torino, Italy; ¹³Rheumatology Department, Santa Maria della Misericordia Hospital, Udine, Italy; ¹⁴Rheumatology and Clinical Immunology, IRCCS Humanitas Research Hospital, Rozzano (MI), Italy; ¹⁵Department of Internal Medicine and Therapeutics, University of Pavia, Istituti Clinici Scientifici Maugeri, Pavia, Italy; ¹⁶Rheumatology Unit, Department of Medicine, University and Azienda Ospedaliera Universitaria Integrata of Verona, Verona, Italy; ¹⁷Rheumatology Unit, Department of Experimental and Internal Medicine, University of Messina, Messina, Italy; ¹⁸Reumatology Unit, Department of Internal, Anesthesiological, and Cardiovascular Clinical Sciences, Sapienza University, Roma, Italy; ¹⁹Miulli General Hospital Acquaviva - Department of Medicine and Surgery, LUM F. De Gennaro University, Casamassima (BA), Acquaviva delle Fonti (BA), Italy.

Società Italiana di Reumatologia

DOI https://doi.org/10.4081/reumatismo.2025.2014
- 341 abstract views
PO:06:081 | Safety of JAK inhibitors compared to non-TNF-targeted biologic therapies in rheumatoid arthritis patients who are inadequate responders to TNF inhibitors

Lorenzo Di Luozzo¹, Alessandro Giollo¹, Mariangela Salvato¹, Francesca Frizzera¹, Kiren Khalid¹, Margherita Zen¹, Andrea Doria¹ | ¹Azienda ospedaliera universitaria di Padova, unità di Reumatologia, Padova, Italy

Società Italiana di Reumatologia

DOI https://doi.org/10.4081/reumatismo.2025.2298
- 189 abstract views
PO:06:082 | Correlation between ultrasonographic parameters and the Krenn synovitis score in patients with chronic infiammatory arthropathy undergoing ultrasound-guided synovial biopsy: a prospective cohort study

Maria Capita¹, Carlo Garaffoni¹, Marianna Tamussin¹, Serena Ceccato¹, Giovanni Lanza², Alessandra Bortoluzzi¹, Marcello Govoni¹, Ettore Silvagni¹ | ¹Unità di Reumatologia, Azienda Ospedaliero - Universitaria S. Anna, Cona (FE); ²Anatomia Patologica, Dipartimento di Medicina Traslazionale Università di Ferrara, Cona (FE), Italy

Società Italiana di Reumatologia

DOI https://doi.org/10.4081/reumatismo.2025.2134
- 286 abstract views
PO:06:083 | Clinical characteristics and outcomes of late- and young-onset rheumatoid arthritis in relation to autoantibody status

Federica Sabatelli^1|2, Ludovico De Stefano^1|2, Clelia Zampaglione^1|2, Lisa Bergianti^1|2, Blerina Xoxi^1|2, Antonio Manzo^1|2, Carlomaurizio Montecucco^1|2, Serena Bugatti^1|2. | ¹Department of Internal Medicine and Therapeutics, University of Pavia, Pavia; ²Division of Rheumatology, IRCCS Policlinico San Matteo Foundation, Pavia, Italy.

Società Italiana di Reumatologia

DOI https://doi.org/10.4081/reumatismo.2025.2015
- 327 abstract views
PO:06:084 | Interstitial lung involvement in rheumatoid arthritis patients treated with abatacept: a prospective observational study

Francesca Cozzini^1|2, Andreina Manfredi^2|3, Antonio Carletto⁴, Elisa Bellis⁵, Laura Cometi⁶, Vincenzo Venerito⁷, Caterina Vacchi⁸, Fabiola Atzeni⁹, Antonio Carriero¹⁰, Rosaria Foti¹¹, Mariagrazia Catanoso³, Ennio Favalli¹², Chiara Bazzani¹³, Arianna Belvedere³, Cecilia Burattini¹, Andrea Morciano⁴, Annamaria Iagnocco⁵, Gemma Lepri⁶, Florenzo Iannone⁷, Antonio Pezzano⁹, Salvatore D'Angelo¹⁰, Valentina Cateni⁴, Serena Guiducci⁶, Marco Sebastiani^1|14. | ¹Ospedale Guglielmo da Saliceto, Piacenza, Italy; ²Università degli studi di Modena e Reggio Emilia, Modena, Italy; ³IRCCS Arcispedale Santa Maria Nuova, Reggio Emilia, Italy; ⁴AOUI, Università degli studi di Verona, Verona, Italy; ⁵A.O. Mauriziano di Torino, Università degli studi di Torino, Torino, Italy; ⁶AOU di Careggi, Università degli studi di Firenze, Firenze, Italy; ⁷AOU Policlinico di Bari, università degli studi di Bari Aldo Moro, Bari, Italy; ⁸AOU Policlinico di Modena, Modena, Italy; ⁹AOU Gaetano Martino, Università degli studi di Messina, Messina, Italy; ¹⁰Azienda Ospedaliera Regionale San Carlo, Potenza, Italy; ¹¹AO Vittorio Emanuele, Catania, Italy; ¹²ASST Gaetano Pini, Milano, Italy; ¹³ASST Spedali Civili, Brescia, Italy; ¹⁴Università degli studi di Parma, Parma, Italy.

Società Italiana di Reumatologia

DOI https://doi.org/10.4081/reumatismo.2025.2016
- 328 abstract views
PO:06:086 | Updated Systematic Literature Review and meta-analysis to Inform the Italian Society of Rheumatology Recommendations on the Treatment of Rheumatoid Arthritis-Associated Interstitial Lung Disease

Angelo Fassio¹, Marco Sebastiani^9|10, Francesco Pollastri¹, Chiara Crotti⁴, Nicola Ughi⁵, Enrico De Lorenzis⁶, Silvia Mancuso⁷, Massimo Radin⁸, Francesca Cozzini⁹, Greta Carrara¹¹, Gianpiero Landolfi¹¹, Roberto Rozza¹¹, Andreina Manfredi^2|3 | ¹Rheumatology Unit, University of Verona, Verona, Italy; ²University of Modena and Reggio Emilia, Reggio Emilia, Italy; ³Rheumatology Unit, AUSL-IRCCS, Reggio Emilia, Italy; ⁴Bone Disease Unit, Department of Rheumatology and Medical Science, ASST-G.Pini-CTO, Milan, Italy; ⁵Division of Rheumatology, Multispecialist Medical Department, ASST Grande Ospedale Metropolitano Niguarda, Milano, Italy; ⁶Department of Aging Diseases, Orthopedic and Rheumatology, Rheumatology Division, P. Gemelli, Roma, Italy; ⁷Rheumatology Unit, Department of Clinical, Internal, Anaesthesiologic and Cardiovascular, Sciences, Sapienza, Roma, Italy; ⁸CMID, San Giovanni Bosco Hub Hospital ASL Città di Torino and Department of Clinical and Biological Sciences, Turin, Italy; ⁹Department of Medicine and Surgery, University of Parma, Parma, Italy; ¹⁰Rheumatology Unit, AUSL Piacenza, Piacenza, Italy; ¹¹Unità Epidemiologica, SIR, Società Italiana di Reumatologia, Milano, Italy

Società Italiana di Reumatologia

DOI https://doi.org/10.4081/reumatismo.2025.2299
- 243 abstract views
PO:06:088 | Are all Difficult-To-Treat RA patients the same? Insights into clinical features and drug discontinuation

Silvia Di Noto¹, Cristina Garufi¹, Letizia Caruso¹, Fulvia Ceccarelli¹, Cristiano Alessandri¹, Federica Ucci¹, Valerio Fiorilli¹, Fabrizio Conti¹, Francesca Romana Spinelli¹ | ¹Sapienza University of Rome, Dipartimento di Scienze Cliniche Internistiche, Anestesiologiche e Cardiovascolari, Roma, Italy

Società Italiana di Reumatologia

DOI https://doi.org/10.4081/reumatismo.2025.2300
- 204 abstract views
PO:06:089 | Heat-not-burn cigarettes induce protein post-translational modifications (PTM): possible role in the pathogenesis of rheumatoid arthritis

Claudia Ciancarella¹, Federica Maria Ucci¹, Valeria Manganelli², Elena Fasciolo², Roberta Priori¹, Fulvia Ceccarelli¹, Manuel Sergi³, Camilla Montesano³, Francesco Bartolini³, Maurizio Sorice², Cristiano Alessandri¹, Fabrizio Conti¹ | ¹Rheumatology Unit, Department of Internal Medicine, Anesthesiology and Cardiovascular Sciences, La Sapienza, Roma, Italy; ²Department of Experimental Medicine, La Sapienza University of Rome, Italy; ³Department of Chemistry, La Sapienza University Of Rome, Italy

Società Italiana di Reumatologia

DOI https://doi.org/10.4081/reumatismo.2025.2301
- 161 abstract views
PO:06:090 | Validation of 'Clinical Red Flags' for RA-ILD in an Italian cohort: the role fo Dyspnea, Cough and Crackles

Eneida Cela¹, Chiara Bonini¹, Francesco Cavalli², Alessandra Luciano³, Barbara Kroegler¹, Josuel Ora², Alberto Bergamini¹, Marcello Chiocchi³, Paola Rogliani², Paola Conigliaro¹, Maria Sole Chimenti¹ | ¹Rheumatology, Allergology and Clinical Immunology, Department of System Medicine, University of Rome Tor Vergata, Rome, Italy; ²Division of Respiratory Medicine, University Hospital Policlinico Tor Vergata, Rome, Italy; ³Department of Diagnostic Imaging and Interventional Radiology, University of Rome, Tor Vergata, Rome, Italy

Società Italiana di Reumatologia

DOI https://doi.org/10.4081/reumatismo.2025.2302
- 116 abstract views
PO:06:092 | Early achievement of remission confers better outcomes than low disease activity in both seropositive and seronegative patients with new-onset rheumatoid arthritis

Clelia Zampaglione^1|2, Ludovico De Stefano^1|2, Federica Sabatelli^1|2, Alessio D'Isanto^1|2, Blerina Xoxi^1|2, Antonio Manzo^1|2, Carlomaurizio Montecucco^1|2, Serena Bugatti^1|2. | ¹Department of Internal Medicine and Therapeutics, University of Pavia, Pavia; ²Division of Rheumatology, IRCCS Policlinico San Matteo Foundation, Pavia, Italy.

Società Italiana di Reumatologia

DOI https://doi.org/10.4081/reumatismo.2025.2017
- 310 abstract views
PO:06:093 | Clinical and ultrasound phenotyping comparison between Difficult-To-Treat Rheumatoid Arthritis (D2TRA) and non-D2TRA patients: experience from a monocentric cohort

Silvia Perrone¹, Claudio Cruciani¹, Silvia Mascolo¹, Elisa Bellis¹, Gloria Crepaldi¹, Valeria Data¹, Claudia Garulli¹, Claudia Lomater¹, Elena Marucco¹, Marta Saracco¹, Mariele Gatto¹, Annamaria Iagnocco¹. | ¹Academic Rheumatology Centre, Department of Clinical and Biological Sciences, University of Turin, AO Mauriziano, Turin, Italy.

Società Italiana di Reumatologia

DOI https://doi.org/10.4081/reumatismo.2025.2018
- 308 abstract views
PO:06:094 | Exploring the relationship between inflammation and collagen deposition in synovial tissue and clinical outcomes in active arthritis: insights from a monocentric pilot study

Dario Bruno¹, Barbara Tolusso¹, Daniela Renna¹, Mohamed Hegazi², Fabio Pasqualini², Marta Caprioli¹, Giacomo Maria Guidelli¹, Tommaso Hubert³, Nicoletta Luciano^1|3, Marzia Monferini³, Natasa Isailovic³, Fabio Grizzi^2|3, Salvatorelorenzo Renne³, Costantino Pitzalis^1|3|4, Elisa Gremese^1|3. | ¹Rheumatology and Clinical Immunology, IRCCS Humanitas Research Hospital, Rozzano (MI); ²Department of Immunology and Inflammation, IRCCS Humanitas Research Hospital, Milano; ³Department of Biomedical Sciences, Humanitas University, Rozzano (MI), Italy; ⁴Centre for Experimental Medicine and Rheumatology, Queen Mary University of London, London, UK

Società Italiana di Reumatologia

DOI https://doi.org/10.4081/reumatismo.2025.2019
- 285 abstract views
PO:07:095 | Clinical impact of therapeutic modification following changes in AIFA reimbursement criteria for JAK inhibitors in patients with RA in remission/low disease activity: analysis of the multicenter JAK-SWAP RER study in Emilia-Romagna

Marta Raschella¹, Giulia Furia¹, Martina Di Nunzio¹, Francesco Luca Renzullo², Francesco Girelli², Federica Pignatti³, Francesco Ursini³, Licia Vultaggio⁴, Pierluigi Cataleta⁴, Elena Bravi⁵, Eugenio Arrigoni⁵, Francesca Bergossi⁶, Enrica Vandelli⁷, Massimo Reta^6|7, Viola Magnani⁸, Andreina Manfredi^8|9, Giuseppe Germanò⁸, Alessandra Bortoluzzi¹, Marcello Govoni¹, Ettore Silvagni¹ | ¹Unità Operativa Complessa di Reumatologia, Dipartimento di Scienze Mediche, Università degli Studi di Ferrara e Azienda Ferrara; ²UOS Reumatologia, Ospedale GB Morgagni, Forlì; ³UOC Reumatologia, Istituto ortopedico Rizzoli, Bologna; ⁴UO Reumatologia, AUSL Romagna Ospedale di Ravenna; ⁵UO Reumatologia, Azienda USL di Piacenza; ⁶Reumatologia Osp. Maggiore, Bologna; ⁷UO Medicina Interna ad Indirizzo Reumatologico Interaziendale ^SC AUSL Bologna, IRCCS Policlinico di SantOrsola, Bologna; ⁸U.O Reumatologia, Santa Maria Nuova di Reggio Emilia; ⁹Università degli studi di Modena e Reggio Emilia, Italy

Società Italiana di Reumatologia

DOI https://doi.org/10.4081/reumatismo.2025.2135
- 323 abstract views
PO:07:096 | Safety of filgotinib in the treatment of rheumatoid arthritis: results from the multicentre SOFIA study

Anna Giorgia Osele¹, Matteo Filippini², Eugenio Capparelli³, Eleonora Bruschi⁴, Bernd Raffeiner⁵, Silvano Bettio⁶, Mariangela Salvato¹, Federico Arru⁷, Massimiliano Limonta⁴, Paola Faggioli³, Elda Piovani², Eleonora Zaccara³, Alessandro Giollo¹, Margherita Zen¹ | ¹UOC Reumatologia, Azienda Ospedale-Università di Padova; ²UO Reumatologia e Immunologia Clinica, ASST Spedali Civili, Brescia; ³UOC Ruematologia, ASST Ovest Milanese, Legnano ^MI; ⁴SSD Reumatologia, ASST Papa Giovanni XXIII, Bergamo; ⁵Dipartimento di Reumatologia, Ospedale di Formazione Paracelsus ^ASDAA-SABES, Bolzano; ⁶Medicina Generale Unità 1^, Centro Regionale per le Malattie Rare Immunologiche e Reumatologiche, Ospedale Universitario Treviso; ⁷UO Medicina, ASL 3 Nuoro, Italy

Società Italiana di Reumatologia

DOI https://doi.org/10.4081/reumatismo.2025.2136
- 302 abstract views
PO:07:097 | CGRP and CALCRL localization supports the role of fibroblast-like synoviocytes in rheumatoid arthritis pain pathways

Giada La Spina¹, Cristina Garufi², Mattia Caliste², Martina Leopizzi³, Valeria Di Maio³, Cristiano Alessandri², Fabrizio Conti², Francesca Romana Spinelli² | ¹Sapienza University of Rome, Dipartimento di Medicina Molecolare, Roma, Italy; ²Sapienza University of Rome, Dipartimento di Scienze Cliniche Internistiche, Anestesiologiche e Cardiovascolari, Roma, Italy; ³Sapienza University of Rome, Dipartimento di Scienze e Biotecnologie Medico-Chirurgiche, Roma, Italy

Società Italiana di Reumatologia

DOI https://doi.org/10.4081/reumatismo.2025.2303
- 122 abstract views
PO:07:098 | Reasons for treatment failure and their synovial correlate among patients with difficult-to-treat rheumatoid arthritis

Alessandro Giollo¹, Mariangela Salvato¹, Francesca Frizzera¹, Kiren Khalid¹, Lorenzo Di Luozzo¹, Carlo Garaffoni², Maria Capita², Marianna Tamussin², Giovanni Lanza², Marny Fedrigo³, Annalisa Angelini³, Roberta Ramonda¹, Ettore Silvagni², Andrea Doria¹ | ¹UOC Reumatologia Padova, Italy; ²UOC Reumatologia Ferrara, Italy; ³UOC Patologia cardiovascolare Padova, Italy; ⁴UOC Anatomia Patologica Ferrara, Italy

Società Italiana di Reumatologia

DOI https://doi.org/10.4081/reumatismo.2025.2304
- 127 abstract views
PO:07:099 | Survival on therapy of certolizumab pegol in rheumatoid arthritis, psoriatic arthritis, and spondyloarthritis: 8-year data from an Italian multicenter register

Maria Manara¹, Gilberto Cincinelli^1|2, Marco Fornaro³, Simone Perniola⁴, Elisa Gremese⁵, Chiara Bazzani⁶, Serena Bugatti⁷, Francesca Romana Spinelli⁸, Rosario Foti⁹, Marco Sebastiani¹⁰, Alberto Cauli¹¹, Fabiola Atzeni¹², Giovanni Lapadula¹³, Gianfranco Ferraccioli¹⁴, Fabrizio Conti⁸, Florenzo Iannone³, Roberto Caporali^1|2 | ¹Department of Rheumatology and Medical Sciences, ASST G. Pini-CTO Milano; ²Department of Clinical Sciences and Community Health, University of Milan; ³Department of Precision and Regenerative Medicine and Ionian Area, University of Bari; ⁴Clinical Immunology Division, Fondazione Policlinico Universitario A. Gemelli IRCCS, Roma; ⁵Rheumatology and Clinical Immunology, IRCCS Humanitas Research Hospital, Rozzano (MI); ⁶Unit of Rheumatology and Clinical Immunology, ASST Spedali Civili Brescia; ⁷Department of Internal Medicine and Therapeutics, Università di Pavia; ⁸Rheumatology Unit, Dipartimento Scienze Cliniche Internistiche, Anestesiologiche e Cardiovascolari, Sapienza University, Roma; ⁹Rheumatology Unit, San Marco Hospital, Policlinico University of Catania; ¹⁰Rheumatology Unit, AUSL Piacenza, University of Parma; ¹¹UOC di Reumatologia, Dipartimento di Scienze Mediche e Sanità Pubblica, Azienda Ospedaliero-Universitaria di Cagliari; ¹²Rheumatology Unit, Department of Experimental and Internal Medicine, University of Messina; ¹³Gruppo Italiano di Studio sulla Early Arthritis, GISEA, Bari; ¹⁴Department of Medicine, Università Cattolica del Sacro Cuore, Fondazione IRCCS Policlinico Gemelli, Roma, Italy

Società Italiana di Reumatologia

DOI https://doi.org/10.4081/reumatismo.2025.2137
- 422 abstract views
PO:07:101 | Efficacy and safety of methotrexate in a cohort of patients affected by early-onset rheumatoid arthritis: a monocentric real-life study

Carlo Cauli¹, Martina Favretti², Giulio Dolcini², Vincenzo Ferraro¹, Cristina Iannuccelli³, Fabrizio Conti¹, Manuela Di Franco¹ | ¹UOC Reumatologia, Dipartimento di scienze cliniche internistiche anestesiologiche e cardiovascolari, Sapienza, Roma; ²Dipartimento di Medicina Molecolare, La Sapienza, Roma; ³UOC Reumatologia, AOU Policlinico Umberto I, La Sapienza, Roma, Italy

Società Italiana di Reumatologia

DOI https://doi.org/10.4081/reumatismo.2025.2138
- 366 abstract views
PO:07:102 | Predicting success with baricitinib in rheumatoid arthritis: efficacy across ages and serological profiles

Daniele Lini¹, Matteo Colina², Romina Andracco³, Francesca Ometto⁴, Viviana Ravagnani⁵, Alberto Lo Gullo⁶, Simone Parisi⁷, Antonella Farina⁸, Patrizia Del Medico⁹, Marino Paroli¹⁰, Olga Addimanda¹, Alessandra Bezzi¹¹, Federica Lumetti¹², Aldo Biagio Molica Colella¹³, Davide Murgia¹⁴, Maddalena Larosa¹⁵, Aurora Ianniello¹⁶, Elena Bravi¹⁷, Marta Priora¹⁸, Palma Scolieri¹⁹, Alessandro Volpe²⁰. | ¹Azienda Unità Sanitaria Locale di Bologna -- Policlinico S.Orsola- Azienda Ospedaliera Universitaria-IRCCS di Bologna, Bologna; ²Rheumatology Service. Department of Medicine and Oncology, Ospedale Santa Maria della Scaletta, Imola; ³Imperia Hospital, Internal Medicine Unit, Rheumatology outpatient clinic, Imperia; ⁴Azienda ULSS 6 Euganea, Rheumatology Outpatient Clinic, Padova; ⁵Santa Chiara Hospital APSS Trento, Rheumatology Unit, Trento; ⁶ARNAS Garibaldi di Catania, Rheumatology Unit, Catania; ⁷Azienda Ospedaliera Universitaria Città della Salute e della Scienza di Torino, Rheumatology Department, Torino; ⁸Ospedale A. Murri di Fermo, Internal Medicine Unit, Rheumatology outpatient clinic, Fermo; ⁹Civitanova Marche Hospital, Rheumatology outpatient clinic - Internal Medicine Unit, Civitanova Marche; ¹⁰Sapienza University of Rome, Polo Pontino, Department of Clinical, Anesthesiological and Cardiovascular Sciences, Latina; ¹¹ASL Romagna Rimini, Internal Medicine and Rheumatology Unit, Rimini; ¹²Azienda USL of Modena and University Hospital Policlinico di Modena, Rheumatology Unit, Modena; ¹³Rheumatology Unit, Azienda Ospedaliera Papardo, Messina; ¹⁴ASL VC Ospedale S. Andrea, Unit of Rheumatology, Vercelli; ¹⁵Azienda Sanitaria Locale 3 Genova, Division of Rheumatology - Medical Specialties Department, Genova; ¹⁶ASL Novara, Rheumatology Outpatient Unit, Novara; ¹⁷Ospedale G. Da Saliceto, Rheumatology Unit, Piacenza; ¹⁸ASL CN1, Rheumatology Day Hospital and outpatient clinic, Mondovì (CN); ¹⁹Nuovo Regina Margherita Hospital, Department of Medical Specialties, Roma; ²⁰IRCCS Sacro Cuore Don Calabria Hospital, Unit of Rheumatology, Negrar, Italy.

Società Italiana di Reumatologia

DOI https://doi.org/10.4081/reumatismo.2025.2020
- 367 abstract views
PO:07:103 | Tocilizumab use in patients with rheumatoid arthritis and malignancy: a monocentric experience

Vittorio Dibenedetto^1|2|3, Nicola Farina^1|2, Nicola Boffini^1|2, Alessandro Tomelleri^1|2, Adriana Cariddi^1|2, Elena Baldissera^1|2, Marco Matucci-Cerinic^1|2|3, Lorenzo Dagna^1|2|3. | ¹Unit of Immunology, Rheumatology, Allergy and Rare Diseases, IRCCS San Raffaele Hospital, Milano, Italy; ²Inflammation, Fibrosis and Ageing Intitiative ^INFLAGE, IRCCS San Raffaele Hospital, Milano, Italy; ³Vita-Salute San Raffaele University, Milano, Italy.

Società Italiana di Reumatologia

DOI https://doi.org/10.4081/reumatismo.2025.2021
- 362 abstract views
PO:07:107 | Performance of the 2010 ACR/EULAR classification criteria for Rheumatoid Arthritis in a group of elderly onset patients

Alessandra Rai¹, Pierluigi Macchioni¹, Giovanni Barausse², Luigi Boiardi¹, Giuseppe Paolazzi², Carlo Salvarani¹, Andreina Manfredi¹ | ¹University of Modena and Reggio Emilia, USL-IRCCS Reggio Emilia, Italy; ²Rheumatology Unit, Ospedale di Trento, Italy

Società Italiana di Reumatologia

DOI https://doi.org/10.4081/reumatismo.2025.2305
- 191 abstract views
PO:07:108 | Achievement of Treatment Targets and Maintenance of Response with Upadacitinib in Patients with Moderate-to-Severe Rheumatoid Arthritis in a Real-world Setting: Final 2-year Outcomes from the UPHOLD Study

Enrico Marchetta¹, Andrew Östör^2|8, Eugen Feist³, Prodromos Sidiropoulos⁴, Jérôme Avouac⁵, Martin Rebella^6|7, Rajaie Namas⁹, Erin Mcdearmon Blondell¹⁰, Ivan Lagunes¹⁰, Tianming Gao¹⁰, Tim Shaw¹⁰, Suzan Attar¹¹ | ¹AbbVie Srl Roma, Italy; ²Monash University and Emeritus Research, Melbourne, Victoria, Melbourne, Australia; ³Helios Department of Rheumatology and Clinical Immunology, Vogelsang-Gommern, Vogelsang Gommern, Germany; ⁴Faculty of Medicine, University of Crete, Heraklion, Heraklion, Greece; ⁵Service de Rhumatologie, Hôpital Cochin, AP HP Centre Université Paris Cité, Parigi, France; ⁶Departamento de Medicina, Facultad de Medicina, Universidad de la República, Montevideo, Montevideo, Uruguay; ⁷Unidad de Enfermedades Autoinmunes Sistémicas, MUCAM, Montevideo, Montevideo, Uruguay; ⁸Australian National University, Camberra, Australia; ⁹Medical Subspecialties Institute, Division of Rheumatology, Cleveland Clinic Abu Dhabi, United Arab Emirates; ¹⁰AbbVie Inc., North Chicago, Illinois, United States of America Chicago, USA; ¹¹King Abdulaziz University, Jeddah, Saudi Arabia

Società Italiana di Reumatologia

DOI https://doi.org/10.4081/reumatismo.2025.2306
- 142 abstract views
PO:07:111 | Worsening of patient-reported outcomes is an early predictor of disease flare in patients with rheumatoid arthritis in course of treatment with conventional synthetic disease modifying anti-rheumatic drugs

Ludovico De Stefano^1|2, Federica Sabatelli^1|2, Clelia Zampaglione^1|2, Blerina Xoxi², Antonio Manzo^1|2, Carlomaurizio Montecucco^1|2, Serena Bugatti^1|2. | ¹Department of Internal Medicine and Therapeutics, University of Pavia, Pavia, Italy; ²Division of Rheumatology, IRCCS Policlinico San Matteo Foundation, Pavia, Italy.

Società Italiana di Reumatologia

DOI https://doi.org/10.4081/reumatismo.2025.2022
- 325 abstract views
PO:08:113 | Shaping rheumatoid arthritis treatment: clinical and demographic drivers of tsDMARDs versus bDMARDs prescription post-EMA pronouncement on JAK inhibitors - insights from the AMBI-RA study

Riccardo Bertola¹, Beatrice Maranini¹, Carlo Garaffoni¹, Maria Pozzuto¹, Anna Laura Riva Cambrino¹, Alessandro Spinelli¹, Letizia Mamprin¹, Federico Agostini¹, Martina Di Nunzio¹, Marcello Govoni¹, Alessandra Bortoluzzi¹, Ettore Silvagni¹ | ¹Rheumatology Unit, Department of Medical Sciences, University of Ferrara and Azienda Ospedaliero-Universitaria S. Anna, Italy

Società Italiana di Reumatologia

DOI https://doi.org/10.4081/reumatismo.2025.2139
- 358 abstract views
PO:08:114 | The adjuvanted recombinant zoster vaccine is effective in preventing herpes zoster among patients ≥50 years of age with selected autoimmune diseases in the united states: a real-world database analysis (2018–2021)

Rosaria Silvestri¹, Dagna Constenla², Germain Lonnet³, Emmanuel Aris³, Nathalie Servotte³, Ramsanjay Rk⁴, Agnes Mwakingwe-Omari², Huifeng Yun² | ¹GSK Verona, Italy; ²GSK Rockville, USA; ³GSK Wavre, Belgium; ⁴GSK Bengaluru, India

Società Italiana di Reumatologia

DOI https://doi.org/10.4081/reumatismo.2025.2140
- 371 abstract views
PO:08:116 | Rheumatoid nodulosis: incidence, clinical/instrumental description, and phenotypic correlations in patients with rheumatoid arthritis treated with b-DMARDs. A real-life analysis from a monocentric cohort

Stefano Ruggiero¹, Elisa Montebelli³, Simone Bernardi², Marcello Natali⁴, Francesca Martelli¹, Alessandra Caula¹, Federica Landolfini¹, Gabriella Cucinotta¹, Sofia Giulianelli¹, Francesco Girelli² | ¹UOC Medicina Interna, Ospedale Morgagni-Pierantoni; Dipartimento di scienze Mediche e Chirurgiche Università di Bologna; ²UOS Reumatologia, Ospedale Morgagni-Pierantoni, Forlì; ³Università degli Studi di Bologna; ⁴UOC Radiologia, Ospedale Morgagni-Pierantoni, Forlì, Italy

Società Italiana di Reumatologia

DOI https://doi.org/10.4081/reumatismo.2025.2141
- 331 abstract views
PO:08:117 | Association between the use of oral contraceptives and the development of rheumatoid arthritis: a systematic review and meta-analysis

Annalisa Marino¹, Damiano Currado^1|2, Onorina Berardicurti^1|2, Marta Vomero², Lyubomyra Kun¹, Letizia Pia Di Corcia², Erika Corberi², Francesca Trunfio², Francesca Saracino², Ludovica Lamberti², Leonardo Frasca², Angelo Battista³, Marta Alfano⁴, Silvia Schiavone⁵, Roberto Giacomelli^1|2, Luca Navarini^1|2. | ¹Clinical and Research Section of Rheumatology and Clinical Immunology, Fondazione Campus Bio-Medico, Roma; ²Rheumatology and Clinical Immunology, Department of Medicine, University of Rome Campus Biomedico, School of Medicine, Roma; ³Department of Maternal Science, Paediatric Emergency Service, Sapienza University of Rome, Roma; ⁴Department of Experimental Medicine, Sapienza University of Rome, Roma; ⁵Department of Orthopaedics and Traumatology, Policlinico Tor Vergata Foundation, Roma, Italy

Società Italiana di Reumatologia

DOI https://doi.org/10.4081/reumatismo.2025.2023
- 284 abstract views
PO:08:118 | “Posting Arthritis”: rheumatoid arthritis vs. juvenile idiopathic arthritis contents on social media

Daniele Domanico¹, Saverio La Bella^2|3, Angelica Napoletano¹, Teresa Caferri¹, Angela Carenza¹, Armando Di Ludovico², Marta Rinaldi⁴, Simone Perniola¹, Vincenzo Venerito¹, Giuseppe Lopalco¹, Florenzo Iannone¹. | ¹Rheumatology Unit Department of Precision and Regenerative Medicine Jonian Area, Bari; ²Pediatric Rheumatology Unit University of Chieti-Pescara, Chieti; ³UOC Rheumatology and Autoinflammatory Diseases, IRCCS Istituto Giannina Gaslini, Genova, Italy; ⁴Paediatric Department, John Radcliffe Hospital Oxford University Hospitalsù, Oxford, UK

Società Italiana di Reumatologia

DOI https://doi.org/10.4081/reumatismo.2025.2024
- 350 abstract views
PO:08:119 | Infusional Advantage: Rituximab’s Role in Enhancing Adherence in Multimorbid Rheumatoid Arthritis

Marco Capodiferro¹, Daniele Domanico¹, Angelica Napoletano¹, Giulia Righetti², Patrizia Suppressa², Vincenzo Venerito¹, Giuseppe Lopalco¹, Florenzo Iannone¹, Fabio Cacciapaglia^1|2 | ¹Rheumatology Unit, Department of Precision and Regenerative Medicine and Jonian Area DiMePRe-J University of Bari, Italy; ²Department of Medicine and Surgery, Miulli General Hospital Acquaviva delle Fonti - LUM University Casamassima Bari Acquaviva delle Fonti, Bari, Italy

Società Italiana di Reumatologia

DOI https://doi.org/10.4081/reumatismo.2025.2307
- 163 abstract views
PO:08:121 | Correlation between SENS score and perceived disability in a monocentric cohort of patients affected by rheumatoid arthritis: preliminary analysis of 209 patients

Francesco Angius¹, Nicoleta Anamari Costin¹, Mattia Fadda¹, Davide Corradini², Mattia Congia², Elisabetta Chessa², Alberto Floris¹, Matteo Piga^{1 -2}, Alberto Cauli^{1 -2} | ¹SC Reumatologia, Dipartimento di Scienze Mediche e Salute Pubblica, Università di Cagliari; ²SC Reumatologia, AOU Cagliari, Italy

Società Italiana di Reumatologia

DOI https://doi.org/10.4081/reumatismo.2025.2142
- 255 abstract views
PO:08:124 | An exploratory analysis of risk factors for methotrexate-associated osteopathy: a retrospective study

Federico Aldegheri¹, Francesca Ruzzon¹, Matteo Appoloni¹, Maurizio Rossini¹, Giovanni Adami¹, Davide Gatti¹, Ombretta Viapiana¹, Angelo Fassio¹ | ¹Università di Verona, Italy

Società Italiana di Reumatologia

DOI https://doi.org/10.4081/reumatismo.2025.2308
- 192 abstract views
PO:08:126 | Use of upadacitinib in real-life: the experience of Calabrian rheumatology

Vincenzo Raimondo¹, Maurizio Caminiti², Pietro Gigliotti³, Giuseppe Varcasia⁴, Massimo L'Andolina⁵, Domenico Olivo⁶, Roberta Pellegrini⁷, Pietro Muto⁸, Marilena Calabria⁹, Laura Massaro¹⁰, Jessica Maria El Luppino¹¹, Salvatore De Bonis¹², Giuseppa Pagano Mariano², Stefania Sorbara³, Virginia Caira⁴, Mariateresa Cirillo⁵, Caterina Bruno⁹, Clodoveo Ferri¹¹ | ¹UOC di Reumatologia, Dipartimento SCIAC, Sapienza Università di Roma; ²Dipartimento di Medicina, Clinica di Reumatologia, Università degli Studi di Udine; ³UOC Medicina Interna e Nefrologia, Dipartimento MeSVA, Università degli Studi di L'Aquila; ⁴UniCamillus, San Camillo Università Internazionale di Scienze della Salute di Roma, Italy; ⁵Ambulatorio di Reumatologia, Ospedale di Tropea, Tropea, Italy; ⁶ASP Crotone, Ambulatorio di Reumatologia, Crotone, Italy; ⁷Ambulatorio di Reumatologia, Ospedale Annunziata di Cosenza, Cosenza, Italy; ⁸Ambulatorio di Reumatologia, Ospedale di Paola, Paola, Italy; ⁹Ambulatorio di Reumatologia, SOC di Medicina Interna, AOU Dulbecco, Catanzaro, Italy; ¹⁰Ambulatorio di Reumatologia, Ospedale di Praia a Mare, Praia a Mare, Italy; ¹¹Casa di Cura Madonna dello Scoglio, Reparto di Reumatologia, Cotronei, Italy - Affiliazione 12: Ambulatorio di Reumatologia, ospedale di Acri, Acri, Italy

Società Italiana di Reumatologia

DOI https://doi.org/10.4081/reumatismo.2025.2143
- 300 abstract views
PO:09:134 | The impact of intra-articular hyaluronic acid injections on osteoarthritis synovitis: a study on synovial tissue of total knee arthroplasty patients

Orazio De Lucia¹, Laura Giudice^1|2, Carolina Artusi¹, Luca Ingrao^1|2, Giorgia Trignani^1|2, Matteo Ferrito¹, Andrea Amati^1|2, Marta Arese^1|2, Camilla Riboldi^1|2, Isabella Scotti¹, Antonella Murgo¹, Ennio Giulio Favalli^1|2, Antonina Parafioriti³, Elisabetta Armiraglio³, Andrea Di Bernardo³, Filippo Calanna⁴, Chiara Fossati⁴, Pietro Simone Randelli^4|5, Roberto Felice Caporali^1|2 | ¹Dipartimento di Reumatologia e Scienze Mediche,ʁSST Centro Specialistico Ortopedico Traumatologico Gaetano Pini-CTO, Milano; ²Dipartimento di Scienze Cliniche e di Comunità, Università degli Studi di Milano; ³UOC Anatomia Patologica, ASST Centro Specialistico Ortopedico Traumatologico Gaetano Pini-CTO, Milano; ⁴UOC 1° Clinica Ortopedica, ASST Centro Specialistico Ortopedico Traumatologico Gaetano Pini-CTO, Milano; ⁵Università degli Studi di Milano, Dipartimento di Scienze Biomediche per la Salute, Milano, Italy

Società Italiana di Reumatologia

DOI https://doi.org/10.4081/reumatismo.2025.2144
- 293 abstract views
PO:09:139 | Comparative evaluation of GPT-4.0, Claude 4, and MedGEMMA in automatic Kellgren-Lawrence grading of knee osteoarthritis

Teresa Caferri¹, Vincenzo Venerito¹, Angela Carenza¹, Daniele Catamerò¹, Daniele Domanico¹, Sergio Del Vescovo¹, Lucia Cristiana Colaprico¹, Lavista Marlea¹, Maria Giannotta¹, Giuseppe Lopalco¹, Florenzo Iannone¹. | ¹Rheumatology Unit, Department of Precision and Regenerative Medicine and Jonian Area, University of Bari, Bari, Italy.

Società Italiana di Reumatologia

DOI https://doi.org/10.4081/reumatismo.2025.2025
- 408 abstract views
PO:10:141 | A Case Study: Navigating the VEXAS Syndrome Mimickers

Erika Montabone¹, Richard Borrelli¹, Nicolò Rashidy¹, Fabiana Giannoccaro², Giuseppe Guida², Federico Itri³, Renato Carignola⁴, Simone Negrini¹, Stefania Nicola¹, Luca Lo Sardo¹, Iuliana Badiu¹, Federica Corradi¹, Ambra Bonvicino⁵, Maurizio Balbi⁶, Luisa Brussino¹ | ¹SCDU Immunologia e Allergologia, AO Mauriziano, Dipartimento di Scienze Mediche, Università degli Studi di Torino Torino, Italy; ²SSD Asma grave, malattie rare del polmone e fisiopatologia respiratoria, AOU San Luigi Gonzaga Orbassano, Italy; ³SCDU Medicina Interna ad indirizzo Ematologico, AOU San Luigi Gonzaga Orbassano, Italy; ⁴SCDU Medicina Interna, Scleroderma Unit, AOU San Luigi Gonzaga Orbassano, Italy; ⁵SCDU Dermatologia, Città della Salute e della Scienza di Torino Torino, Italy; ⁶SCDU Radiodiagnostica, AOU San Luigi Gonzaga, Dipartimento di Oncologia Orbassano, Italy

Società Italiana di Reumatologia

DOI https://doi.org/10.4081/reumatismo.2025.2309
- 211 abstract views
PO:10:144 | Management of pure red cell aplasia as the onset of systemic lupus erythematosus: a case report

Chrystel Carolin Navarrete Cadena¹, Marika Tardella¹ | ¹Università Politecnica delle Marche Jesi, Ancona, Italy

Società Italiana di Reumatologia

DOI https://doi.org/10.4081/reumatismo.2025.2310
- 264 abstract views
PO:10:146 | Dorsal myelopathy in a patient with radiographic axial spondyloarthritis

Chiara Nobili¹, Siria Ripiccini¹, Marco Panetta¹, Elisabetta Greco¹, Barbara Kroegler¹, Paola Conigliaro¹, Alberto Bergamini¹, Maria Sole Chimenti¹ | ¹Università degli Studi di Roma-Tor Vergata, Italy

Società Italiana di Reumatologia

DOI https://doi.org/10.4081/reumatismo.2025.2145
- 256 abstract views
PO:10:149 | Efficacy of anifrolumab in a case of systemic lupus erythematosus with pulmonary involvement

Fabio Brandolino¹, Giulia Pazzola¹, Luca Ronzoni³, Andreina Teresa Manfredi^1|2, Carlo Salvarani^1|2 | ¹SC Reumatologia, IRCCS Arcispedale Santa Maria Nuova, AUSL Reggio Emilia; ²Università di Modena e Reggio Emilia, Scuola di specializzazione in Reumatologia, Modena; ³SC Malattie dell'Apparato Respiratorio, IRCCS Arcispedale Santa Maria Nuova, AUSL Reggio Emilia, Italy

Società Italiana di Reumatologia

DOI https://doi.org/10.4081/reumatismo.2025.2146
- 479 abstract views
PO:10:150 | A case of pulmonary hypertension in Whipple's disease

Alba Chiara Pozzi^1|2, Giulia Fontana^1|2, Francesca Crisafulli^1|2, Guarino Daniele³, Monica Salvi³, Massimiliano Palazzini³, Francesco Biagi^4|5, Ilaria Cavazzana^1|2, Franco Franceschini^1|2, Micol Frassi¹. | ¹Rheumatology and Clinical Immunology Unit ERN-ReCONNECT, ASST Spedali Civili, Brescia, Italy; ²Department of Clinical Experimental Sciences, University of Brescia, Brescia; ³IRCCS Azienda Ospedaliero-Universitaria di Bologna, University of Bologna, Cardiology Unit, DIMEC, Bologna; ⁴University of Pavia, Department of Internal Medicine and Therapeutics, Pavia; ⁵Istituti Clinici Scientifici Maugeri IRCCS, Gastroenterology Unit of Pavia Institute, Pavia, Italy.

Società Italiana di Reumatologia

DOI https://doi.org/10.4081/reumatismo.2025.2026
- 332 abstract views
PO:10:153 | Isolated sarcoidosis of the parotid gland: a rare case of unilateral presentation

Irene Carlino¹, Giorgio Carlino², Silvia Lombardo³, Luigi Gennari¹ | ¹Internal Medicine Unit, Department of Medicine Surgery and Neuroscience, University of Siena; ²ASL Lecce, Rheumatology Service DSS Casarano-Gallipoli-Gagliano del Capo, Gallipoli (LE); ³ASL Lecce, DSS Gagliano del Capo, Ugento (LE); Italy

Società Italiana di Reumatologia

DOI https://doi.org/10.4081/reumatismo.2025.2147
- 303 abstract views
PO:10:154 | Pudendal nevralgia as an unusual presenting symptom of axial spondyloarthritis

Benedetta Bongiovanni¹, Gabriele Amati¹, Gilda Sandri^1|2, Giovanni Ciancio², Dilia Giuggioli^1|2 | ¹Struttura complessa di Reumatologia, azienda ospedaliera universitaria Policlinico di Modena; ²Cattedra di Reumatologia, università degli studi di Modena e Reggio Emilia, Modena, Italy

Società Italiana di Reumatologia

DOI https://doi.org/10.4081/reumatismo.2025.2148
- 458 abstract views
PO:10:155 | Etanercept-induced lupus in a patient with rheumatoid arthritis: diagnostic challenges and multidisciplinary therapeutic approach

Camilla Riboldi^1|2, Claudia Iannone^1|2, Maria Gerosa^1|2, Roberto Felice Caporali^1|2 | ¹ASST G. Pini-CTO, U.O.C. di Clinica Reumatologica, Milano; ²Dipartimento di Scienze Cliniche e di Comunità, Università degli Studi di Milano, Italy

Società Italiana di Reumatologia

DOI https://doi.org/10.4081/reumatismo.2025.2149
- 404 abstract views
PO:10:157 | Sjögren’s syndrome with cryoglobulinemia associated with POEMS syndrome

Andrea Mazzon¹, Elena Bianchi¹, Virginia Berlengiero¹, Luca Cantarini¹, Bruno Frediani¹, Enrico Selvi¹ | ¹Azienda Ospedaliera Universitaria Senese Le Scotte, Siena, Italy

Società Italiana di Reumatologia

DOI https://doi.org/10.4081/reumatismo.2025.2150
- 347 abstract views
PO:11:158 | Osteomyelitis of the jaw: a rare mimick of giant cell arteritis

Laura Gigante¹, Giovanni B. Canestrari¹, Olga Addimanda¹, Francesca Bergossi¹, Angela Buffa¹, Francesco Cianci¹, Daniela Chiarini¹, Niccolò Girolimetto¹, Daniele Lini¹, Luca Magnani¹, Mirco Magnani¹, Erika Meleddu¹, Francesca Pignataro¹, Sofia Testoni¹, Alarico Ariani¹, Rita Mulè¹, Elisa Rossi¹, Enrica Vandelli¹, Gentiana Vukatana¹, Antonella Gamberini¹, Massimo Reta¹ | ¹UO interaziendale Medicina Interna ad Indirizzo Reumatologico - AUSL Bologna - AOSP Sant'Orsola Bologna, Italy

Società Italiana di Reumatologia

DOI https://doi.org/10.4081/reumatismo.2025.2151
- 457 abstract views
PO:11:162 | DRESS syndrome: a case treated with mepolizumab

Alessandro Belotti Masserini¹, Stefania Bertocchi¹, Eleonora Bruschi¹, Silvia Breda¹, Valeria Rossi¹, Elide Lupi¹, Tania Ubiali¹, Fabrizio Angeli¹, Massimiliano Limonta¹ | ¹ASST Papa Giovanni XXIII, Bergamo, Italy

Società Italiana di Reumatologia

DOI https://doi.org/10.4081/reumatismo.2025.2152
- 445 abstract views
PO:11:165 | Clinical mimicry and therapeutic challenge: A Case of Rapidly Progressive Mixed Connective Tissue Disease

Elena Maria Di Virgilio¹, Elisabetta Chessa², Valentina Ibba², Cosimina Matulli², Jessica Sorgia¹, Andrea Pace¹, Matteo Piga^1|2, Alberto Cauli^1|2 | ¹Università degli studi di Cagliari-Reumatologia, Cagliari, Italy; ²Struttura complessa di Reumatologia- AOU Cagliari, Cagliari, Italy

Società Italiana di Reumatologia

DOI https://doi.org/10.4081/reumatismo.2025.2311
- 258 abstract views
PO:11:167 | Subtle symptoms masking a challenging diagnosis: a clinical case of intestinal vasculitis in systemic lupus erythematosus

Ilaria Pace¹, Giulia Rizzo¹, Elisabetta Chessa², Davide Corradini¹, Roberta Origa¹, Valentina Ibba², Alberto Floris^1|2, Alberto Cauli^1|2, Matteo Piga^1|2 | ¹Sapienza Università di Roma; ²SC Reumatologia, AOU Cagliari, Cagliari, Italy

Società Italiana di Reumatologia

DOI https://doi.org/10.4081/reumatismo.2025.2153
- 765 abstract views
PO:11:170 | When Paget Meets Inflammatory Back Pain: A Diagnostic Dilemma Between Bone Remodeling and Spondyloarthritis

Marco Capodiferro¹, Giuseppe Lopalco¹, Giulia Righetti², Gianluigi Della Corte², Patrizia Suppressa², Florenzo Iannone¹, Fabio Cacciapaglia^1|2 | ¹Unit of Rheumatology, Department of Precision and Regenerative Medicine, Area Jonica DiMePRe-J, University of Bari, Italy; ²Miulli General Hospital Acquaviva - Department of Medicine and Surgery, LUM F. De Gennaro University, Casamassima, Bari, Acquaviva delle Fonti, Italy

Società Italiana di Reumatologia

DOI https://doi.org/10.4081/reumatismo.2025.2312
- 262 abstract views
PO:11:171 | Subcutaneous tocilizumab use in a young-onset mixed connective tissue disease patient with multiple treatment failures

Rhaysa Araujo Mousinho¹, Elide Lupi², Massimiliano Limonta² | ¹Clinica di Reumatologia, Dipartimento di Medicina and ²Istituto di Anatomia Patologica, Dipartimento di Medicina di Laboratorio, Osp. S. M. della Misericordia, Università di Udine, Italy

Società Italiana di Reumatologia

DOI https://doi.org/10.4081/reumatismo.2025.2154
- 374 abstract views
PO:11:172 | Not all vasculitis look the same: a difficult diagnosis

Marta Arese^1|2, Miriam Perino^1|2, Sofia Aliprandi^1|2, Antonella Murgo², Maria Gerosa^1|2, Roberto Felice Caporali^1|2 | ¹UOC Reumatologia AOR San Carlo, Potenza; ²Reumatologia Clinica, ASST Gaetano Pini-CTO, Milano, Italy

Società Italiana di Reumatologia

DOI https://doi.org/10.4081/reumatismo.2025.2155
- 305 abstract views
PO:11:175 | Dermatomyositis and immunosuppressant treatment: a case of Staphylococcus aureus pneumonia in a hospitalized patient

Simona Fichera¹, Andrea Cito¹, Martina Vigilia¹, Maria Morrone¹, Teresa Caferri¹, Crescenzio Scioscia¹, Simone Perniola¹, Giuseppe Lopalco¹, Florenzo Iannone¹. | ¹Unit of Rheumatology, Department of Precision and Regenerative Medicine, Area Jonica, University of Bari, Bari, Italy.

Società Italiana di Reumatologia

DOI https://doi.org/10.4081/reumatismo.2025.2027
- 383 abstract views
PO:12:177 | Systemic inflammation and QTc interval prolongation in new-onset polymyalgia rheumatica: the effect of corticosteroid therapy

Anna Colangelo¹, Riccardo Accioli², Viola Salvini², Francesco Tromby¹, Giulia Cruciani¹, Martina Nicchi¹, Biancamaria Pianese¹, Francesca Lalli¹, Anna Cantore², Caterina Antonini¹, Decoroso Verrengia², Andrea Castellucci¹, Giacomo Cafaro¹, Carlo Perricone¹, Roberto Gerli¹, Pietro Enea Lazzerini², Elena Bartoloni¹ | ¹SC Reumatologia. Università di Perugia, Italy; ²Dipartimento di Scienze Mediche, Università di Siena, Italy

Società Italiana di Reumatologia

DOI https://doi.org/10.4081/reumatismo.2025.2313
- 231 abstract views
PO:12:178 | Don't count your chickens before they hatch! Analysis of cardiovascular definitions in studies on rheumatic diseases: a systematic literature review

Laura Pezzoni¹, Silvia Sirotti^1|2, Georgios Filippou^1|2, Piercarlo Sarzi Puttini^1|2, Greta Pellegrino^1|2. | ¹Università degli Studi di Milano, Milano; ²IRCCS Ospedale Galeazzi Sant'Ambrogio, Milano, Italy.

Società Italiana di Reumatologia

DOI https://doi.org/10.4081/reumatismo.2025.2028
- 297 abstract views
PO:12:179 | Cardiovascular outcomes of treat-to-target urate-lowering therapy in gout: emulated target trials

Edoardo Cipolletta¹, Davide Rozza², Abhishek Abhishek³ | ¹Azienda Ospedaliero Universitaria delle Marche, Ancona, Italy; ²Società Italiana di Reumatologia, Milano, Italy; ³University of Nottingham Nottingham, United Kingdom

Società Italiana di Reumatologia

DOI https://doi.org/10.4081/reumatismo.2025.2314
- 206 abstract views
PO:12:180 | Echocardiographic screening of pulmonary hypertension in a multidisciplinary cohort of patients with interstitial lung disease

Lorenzo Mattia Bianchessi¹, Veronica Piccin¹, Federica Sabatelli¹, Lorenzo Cavagna¹, Giovanni Zanframundo¹, Domenicafederica Briganti², Mauro Acquaro³, Stefano Ghio³, Domenico Sorace¹, Valentina Vertui², Ilaria Giana², Andrea Patanè³, Veronica Codullo¹ | ¹UOC Reumatologia, Fondazione IRCCS Policlinico S. Matteo, Pavia; ²Centro Trapianti, Fondazione IRCCS Policlinico San Matteo, Pavia; ³UOC Cardiologia, Fondazione IRCCS Policlinico San Matteo, Pavia, Italy

Società Italiana di Reumatologia

DOI https://doi.org/10.4081/reumatismo.2025.2156
- 322 abstract views
PO:12:183 | Acute effect of anti-TNF therapy on atrioventricular conduction in chronic inflammatory arthritis: a prospective cohort study

Viola Salvini¹, Riccardo Accioli¹, Anna Cantore¹, Fabio Salvadori¹, Enrico Selvi², Virgina Berlengerio², Maurizio Acampa³, Alessandra Cartocci¹, Decoroso Verrengia¹, Kateryna Miedviedieva¹, Sciaila Bernardini¹, Michele Voglino¹, Maurizio Bicchi¹, Daniela Merlotti¹, Stefania Bisogno¹, Pier Leopoldo Capecchi¹, Pietro Enea Lazzerini¹ | ¹Division of Internal Medicine, Electroimmunology Unit, University Hospital of Siena, Italy; ²Division of Rheumatology, University Hospital of Siena, Italy; ³Stroke Unit, University Hospital of Siena, Italy

Società Italiana di Reumatologia

DOI https://doi.org/10.4081/reumatismo.2025.2315
- 222 abstract views
PO:12:184 | Atrioventricular conduction in chronic inflammatory arthritis: enhanced assessment by new electrocardiographic parameters

Riccardo Accioli¹, Viola Salvini¹, Anna Cantore¹, Fabio Salvadori¹, Enrico Selvi², Virgina Berlengiero², Maurizio Acampa³, Alessandra Cartocci¹, Kateryna Miedviedieva¹, Decoroso Verrengia¹, Sciaila Bernardini¹, Michele Voglino¹, Giovanni Donati¹, Silvia Petri¹, Severino Gallo¹, Stefania Bisogno¹, Pier Leopoldo Capecchi¹, Pietro Enea Lazzerini¹ | ¹Division of Internal Medicine, Electroimmunology Unit, University Hospital of Siena, Italy; ²Division of Rheumatology, University Hospital of Siena, Italy; ³Stroke Unit, University Hospital of Siena, Italy

Società Italiana di Reumatologia

DOI https://doi.org/10.4081/reumatismo.2025.2316
- 178 abstract views
PO:12:186 | Clinical, functional, and microvascular features in the early diagnosis and management of pulmonary hypertension in systemic sclerosis: the importance of multimodal screening strategies

Irene Carlino¹, Stefania Bisogno¹, Alberto Palazzuoli², Luigi Gennari¹ | ¹U.O.C. Reumatologia, Dipartimento di Scienze Mediche, Chirurgiche e Neuroscienze, Università di Siena, A.O.U. Senese; ²Azienda Sanitaria Locale, Novara, Italy

Società Italiana di Reumatologia

DOI https://doi.org/10.4081/reumatismo.2025.2157
- 322 abstract views
PO:12:187 | Maternal Hypertensive Disorders in Pregnant Women with Rheumatic Diseases and long-term Cardiovascular Outcomes: preliminary data of a single centre experience

Margherita Rinaldi¹, Paolo Semeraro¹, Francesca Crisafulli¹, Matteo Filippini², Maria Grazia Lazzaroni¹, Cecilia Nalli¹, Liala Moschetti¹, Marco Taglietti², Chiara Loardi³, Rossana Orabona³, Francesca Ramazzotto³, Sonia Zatti³, Laura Andreoli¹, Angela Tincani¹, Micaela Fredi¹, Ilaria Cavazzana¹, Franco Franceschini¹ | ¹Department of Clinical and Experimental Sciences, University of Brescia, Italy; ²Rheumatology and Clinical Immunology, ASST Spedali Civili of Brescia, ERN-ReCONNET Center Brescia, Italy; ³Gynaecology and Obstetrics Unit ASST Spedali Civili di Brescia, Italy

Società Italiana di Reumatologia

DOI https://doi.org/10.4081/reumatismo.2025.2317
- 221 abstract views
PO:13:188 | Menstrual alterations among women with rheumatoid arthritis: a comparative study across treatment modalities with focus on JAK inhibitors

Angelica Napoletano¹, Francesca Arezzo², Marco Fornaro¹, Giuseppe Lopalco¹, Gennaro Cormio², Vincenzo Venerito¹, Florenzo Iannone¹. | ¹University of Bari, Rheumatology Unit Department of Precision and Regenerative Medicine, Jonica Area, Bari; ²Gynecologic Oncology, IRCCS Istituto Tumori Giovanni Paolo II, Bari, Italy.

Società Italiana di Reumatologia

DOI https://doi.org/10.4081/reumatismo.2025.2029
- 773 abstract views
PO:13:189 | Greater impact of psoriatic arthritis in females: is this mediated primarily by disease activity?

Roberta Masnata¹, Valentina Boni¹, Giusy Peluso¹, Giulia Calabrese¹, Enrico De Lorenzis¹, Gerlando Natalello¹, Maria Antonietta D'Agostino¹, Augusta Ortolan¹. | ¹UOC Reumatologia e Immunologia Clinica- Fondazione Policlinico Agostino Gemelli IRCCS-Università Cattolica Sacro Cuore, Roma, Italy.

Società Italiana di Reumatologia

DOI https://doi.org/10.4081/reumatismo.2025.2030
- 338 abstract views
PO:14:193 | Dapirolizumab Pegol Demonstrated Significant Improvement in Systemic Lupus Erythematosus Disease Activity: Efficacy and Safety Results of a Phase 3 Trial

Megan EB Clowse¹, Marta Mosca², David A Isenberg³, Joan T Merrill⁴, Thomas Dörner⁵, Michelle Petri⁶, Edward M Vital^7|8, Eric F Morand⁹, Teri Jimenez¹⁰, Stephen Brookes¹¹, Janine Gaiha-Rohrbach¹², Christophe Martin¹³, Annette Nelde¹⁴, Christian Stach¹⁵ | ¹Duke University - Division of Rheumatology and Immunology Durham, USA; ²University of Pisa - Rheumatology Unit, Department of Clinical and Experimental Medicine Pisa, Italy; ³University College London - Department of Ageing, Rheumatology and Regenerative Medicine, Division of Medicine London, United Kingdom; ⁴Oklahoma Medical Research Foundation Oklahoma City, USA; ⁵Charité Universitätsmedizin Berlin - Department of Medicine/Rheumatology and Clinical Immunology Berlin Germany; ⁶Johns Hopkins University School of Medicine Baltimore, USA; ⁷University of Leeds - Leeds Institute of Rheumatic and Musculoskeletal Medicine Leeds, United Kingdom; ⁸Leeds Teaching Hospitals NHS Trust - NIHR Leeds Biomedical Research Centre Leeds, United Kingdom; ⁹Monash University - Centre for Inflammatory Diseases Melbourne, Australia; ¹⁰UCB Raleigh, USA; ¹¹Biogen Maidenhead, United Kingdom; ¹²Biogen Cambridge, USA; ¹³UCB Slough, United Kingdom; ¹⁴Biogen Baar, Switzerland; ¹⁵UCB Monheim am Rhein, Germany

Società Italiana di Reumatologia

DOI https://doi.org/10.4081/reumatismo.2025.2318
- 228 abstract views
PO:14:194 | The CORAL Study: Complement levels during pregnancy in prospectively followed systemic Lupus erythematosus patients

Irene Cecchi¹, Massimo Radin¹, Alice Barinotti¹, Francesca Crisafulli², Laura Andreoli², Cecilia Beatrice Chighizola³, Savino Sciascia¹, On Behalf Of The Coral Study Group¹ | ¹Università di Torino, Italy; ²Università di Brescia, Italy; ³Università di Milano, Italy

Società Italiana di Reumatologia

DOI https://doi.org/10.4081/reumatismo.2025.2319
- 127 abstract views
PO:14:195 | Real-world effectiveness of anifrolumab in achieving treatment targets and reducing systemic lupus erythematosus disease burden: 6-month interim analysis of the REVEAL study

Chiara Cardelli^1|2, Chiara Tani¹, Luca Moroni³, Filippo Vesentini⁴, Francesca Bottazzi⁵, Micaela Fredi⁶, Ettore Silvagni⁷, Matteo Piga⁸, Flavia Riccio⁹, Fulvia Ceccarelli¹⁰, Ginevra De Marchi¹¹, Edoardo Biancalana¹², Gianluca Moroncini¹³, Rita Mulè¹⁴, Mariele Gatto¹⁵, Laura Coladonato¹⁶, Paola Conigliaro¹⁷, Maria Gerosa¹⁸, Andrea Picchianti Diamanti¹⁹, Benedetta Bianchi²⁰, Federica Maiolini²⁰, Michela Gasparotto²⁰, Serena Guiducci²⁰, Maria Ilenia De Andres²⁰, Alberto Lo Gullo²⁰, Silvia Noviello²⁰, On Behalf Of The Reveal Investigators²⁰, Marta Mosca¹. | ¹Rheumatology Unit, Department of Clinical and Experimental Medicine, University of Pisa, Pisa; ²Department of Medical Biotechnologies, University of Siena, Siena; ³Unit of Immunology, Rheumatology, Allergy and Rare Diseases, IRCCS San Raffaele Hospital, Milano; ⁴Rheumatology Unit, Department of Medicine, University of Padua, Padova; ⁵Department of Internal Medicine and Therapeutics, University of Pavia, Pavia; ⁶Rheumatology and Clinical Immunology, Department of Clinical and Experimental Sciences, University of Brescia, Brescia; ⁷Section of Rheumatology, Department of Medical Sciences, University of Ferrara; AOU Sant'Anna, Ferrara; ⁸Rheumatology Unit, Department of Medical Sciences and Public Health, University of Cagliari, Cagliari; ⁹Department of Precision Medicine, University of Campania Luigi Vanvitelli, Napoli; ¹⁰Rheumatology Unit, Dept. of Clinical Internal, Anesthesiological and Cardiovascular Sciences, Sapienza University of Rome, Roma; ¹¹Division of Rheumatology, Department of Medicine, Azienda Sanitaria Universitaria del Friuli Centrale, Udine; ¹²Internal Interdisciplinary Medicine Unit, Department of Experimental and Clinical Medicine, University of Florence, Firenze; ¹³Department of Clinical and Molecular Sciences, Marche Polytechnic University, Ancona; ¹⁴Azienda Ospedaliero-Universitaria di Bologna, Internal Medicine and Rheumatology, IRCCS S. Orsola Malpighi, Bologna; ¹⁵Academic Rheumatology Centre, Department of Clinical and Biological Sciences, University of Turin; AO Mauriziano, Torino; ¹⁶Rheumatology Unit, Department of Precision and Regenerative Medicine and Ionian Area, University of Bari, Bari; ¹⁷Rheumatology, Allergology and Clinical Immunology, Department of Systems Medicine, Tor Vergata University of Rome, Roma; ¹⁸Clinical Rheumatology, ASST Gaetano Pini CTO; Department of Clinical Sciences and Community Health, University of Milano, Milano; ¹⁹Department of Clinical and Molecular Medicine, Sapienza University of Rome; AOU Sant'Andrea, Roma, Italy; ²⁰Italian REVEAL Study Group Italy, Italy

Società Italiana di Reumatologia

DOI https://doi.org/10.4081/reumatismo.2025.2031
- 416 abstract views
PO:14:196 | Photosensitivity in Lupus Erythematosus: The Patients' Perspective in a National Survey

Marianna Salis¹, Elisabetta Chessa², Alessandra Oliva¹, Marta Paola Pireddu¹, Fabio Congiu¹, Giulia Rizzo¹, Elena Ragusa¹, Alberto Cauli^1|2, Laurent Arnaud³, Matteo Piga^1|2 | ¹Università degli Studi di Cagliari, Italy; ²Azienda Ospedaliera Universitaria di Cagliari, Unità Operativa Complessa di Reumatologia Cagliari, Italy; ³Strasbourg University and Academic Hospitals Strasbourg, France

Società Italiana di Reumatologia

DOI https://doi.org/10.4081/reumatismo.2025.2320
- 157 abstract views
PO:14:197 | Safety of biologic and conventional immunosuppressants in an Italian cohort of patients with systemic lupus erythematosus: a longitudinal analysis from the Lupus Italian Registry pharmacoepidemiologic study promoted by the Italian Society of Rheumatology

Davide Rozza¹, Carlo Alberto Scirè^1|2, Paola Conigliaro³, Giacomo Emmi⁴, Laura Coladonato⁶, Salvatore Scarpato⁷, Luca Iaccarino⁸, Serena Guiducci⁹, Giulia Pazzola¹⁰, Francesca Romana Spinelli¹¹, Micol Frassi¹², Ilaria Cavazzana¹², Chiara Scirocco¹³, Valeria Orefice¹³, Immacolata Prevete¹³, Alessandra Bortoluzzi¹⁴, Marcello Govoni¹⁴, Elena Bartoloni¹⁵, Luca Moroni¹⁶, Giuseppe Alvise Ramirez¹⁶, Valentina Canti¹⁶, Giorgio Pettiti¹⁷, Maria Chiara Ditto¹⁸, Enrico Fusaro¹⁸, Marta Mosca¹⁹, Lorenzo Cavagna²⁰, Fabrizio Conti¹¹, Andrea Doria⁸, Gian Domenico Sebastiani¹³, Sperimentatori Gruppo Lire⁵ | ¹Centro Studi della Società Italiana di Reumatologia, Milano; ²Dipartimento di Medicina e Chirurgia, Università degli Studi di Milano-Bicocca, Monza; ³Università di Roma Tor Vergata; ⁴Dipartimento di Scienze Mediche, Chirurgiche e della Salute, Università di Trieste; ⁵https://redcap.reumatologia.it/surveys/?s=LWL7WJM4KHDR97CC; ⁶Dip di Medicina di Precisione e Rigenerativa e area Jonica, Bari; ⁷Azienda Sanitaria Locale ^ASL Salerno; ⁸Università degli Studi di Padova; ⁹SOD Reumatologia, Dipartimento di Medicina Sperimentale e Clinica, Università degli Studi di Firenze; ¹⁰Arcispedale Santa Maria Nuova Reggio Emilia; ¹¹Università degli Studi di Roma La Sapienza; ¹²Spedali Civili di Brescia; ¹³Azienda Ospedaliera San Camillo Forlanini, Roma; ¹⁴Azienda Ospedaliera Universitaria Sant'Anna, Ferrara; ¹⁵SC Reumatologia, Dipartimento di Medicina e Chirurgia, Università di Perugia; ¹⁶IRCCS Ospedale San Raffaele, Milano; ¹⁷Azienda Ospedaliera S. Croce e Carle, Cuneo; ¹⁸AOU Citta' della Salute e della Scienza di Torino; ¹⁹AOU Santa Chiara, Pisa; ²⁰Università di Pavia, Italy

Società Italiana di Reumatologia

DOI https://doi.org/10.4081/reumatismo.2025.2158
- 347 abstract views
PO:14:198 | Temporal Trends in LLDAS and DORIS Achievement in SLE: Impact of Evolving International Recommendations

Laura Coladonato¹, Marco Fornaro¹, Angelica Napoletano¹, Daniele Catamerò¹, Giuseppe Lopalco¹, Florenzo Iannone¹ | ¹UOC Reumatologia, Policlinico di Bari, DiMePre-J Bari, Italy

Società Italiana di Reumatologia

DOI https://doi.org/10.4081/reumatismo.2025.2321
- 169 abstract views
PO:14:199 | Preliminary data of a multicentric study on safety and efficacy of assisted reproductive techniques in pregnant women with systemic autoimmune diseases

Valentina Canti¹, Maria Bernadette Cilona¹, Giuditta Gorgone¹, Federica Pasi¹, Antonia Calligaro², Francesca Ruffilli³, Francesca Crisafulli⁶, Maria Tonello², Eleonora Giacobbe⁴, Alba Chiara Pozzi⁶, Maria Chiara Gerardi⁴, Melissa Padovan³, Emanuele Bizzi⁵, Enrico Papaleo¹, Beatrice Maranini³, Marcello Govoni³, Massimiliano Epis⁴, Angela Tincani⁶, Andrea Doria², Patrizia Rovere Querini¹ | ¹IRCCS Ospedale San Raffaele and VitaSalute San Raffaele Milano, Italy; ²Rheumatology Unit, Departement of Medicine, University Hospital of Padua Padova, Italy; ³Rheumatology Unit, Azienda Ospedaliero Universitaria S. Anna Ferrara, Department of Medical Sciences, University of Fe Ferrara, Italy; ⁴ASST Grande Ospedale Metropolitano Niguarda Milano, Italy; ⁵Internal Medicine, Fatebenefratelli Hospital Milano, Italy; ⁶Rheumatology and Immunology Unit, ASST Spedali Civili Brescia e Università degli Studi di Brescia, Italy

Società Italiana di Reumatologia

DOI https://doi.org/10.4081/reumatismo.2025.2322
- 133 abstract views
PO:14:200 | Placental markers of angiogenesis in pregnant women with antiphospholipid syndrome: predictive role of SFLT-1, PLGF, and uterine artery doppler in preeclampsia

Maria Bernadette Cilona¹, Valentina Canti¹, Martina Beschi², Federica Pasi³, Serena Girardelli³, Mirko Pozzoni³, Maria Teresa Castiglioni³, Paolo Cavoretto³, Patrizia Rovere-Querini^1|2 | ¹Unit of Internal Medicine and Division of Immunology, Transplantation and Infectious diseases, IRCCS San Raffaele Hospital Milan, Italy; ²Vita-Salute San Raffaele University Milan, Italy; ³Department of Obstetrics and Gynecology, IRCCS San Raffaele Scientific Institute Milan, Italy

Società Italiana di Reumatologia

DOI https://doi.org/10.4081/reumatismo.2025.2323
- 141 abstract views
PO:14:201 | Olfactory Assessment in Patients with Systemic Lupus Erythematosus: Correlation with Clinical, Serological, and Imaging Markers

Lorenza Bruno¹, Giacomo Cafaro¹, Marta Di Berardino¹, Roberto Dal Pozzolo¹, Anna Colangelo¹, Francesco Tromby¹, Martina Nicchi¹, Giulia Cruciani¹, Biancamaria Pianese¹, Roberto Gerli¹, Elena Bartoloni Bocci¹, Carlo Perricone¹ | ¹Università degli Studi di Perugia, Italy

Società Italiana di Reumatologia

DOI https://doi.org/10.4081/reumatismo.2025.2324
- 298 abstract views
PO:14:202 | Use of anifrolumab in the treatment of the hematological manifestations of systemic lupus erythematosus: a single-centre case series

Gaia Ferracane^1|2, Jessika Dichiara^1|2, Elena Manna^1|2, Lorenzo Mattia Bianchessi^1|2, Giovanni Zanframundo^1|2, Serena Bugatti^1|2, Veronica Codullo^1|2, Lorenzo Cavagna^1|2, Francesca Bottazzi^1|2 | ¹Department of Internal Medicine and Therapeutics, Università di Pavia; ²Division of Rheumatology, IRCCS Policlinico San Matteo, Pavia, Italy

Società Italiana di Reumatologia

DOI https://doi.org/10.4081/reumatismo.2025.2159
- 567 abstract views
PO:14:203 | Impact of anifrolumab on depressive symptoms in systemic lupus erythematosus: results from a single-centre prospective observational study

Luca Moroni¹, Biancamaria Venerandi¹, Maria Cilona¹, Anna Vivona¹, Gabriele Gallina¹, Giovanni Benanti¹, Enrica Bozzolo¹, Giuseppe Ramirez¹, Marco Matucci-Cerinic¹, Lorenzo Dagna¹. | ¹U.O. di Immunologia, Reumatologia, Allergologia e Malattie Rare - IRCCS Ospedale San Raffaele, Milano, Italy.

Società Italiana di Reumatologia

DOI https://doi.org/10.4081/reumatismo.2025.2032
- 306 abstract views
PO:14:204 | Risk stratification in systemic lupus erythematosus patients: improving the performances of a prediction model

Lucia Lanzo¹, Silvia Laura Bosello¹, Livia Lilli², Laura Antenucci², Carlotta Masciocchi², Marco Gorini³, Gabriella Castellino³, Luca Petricca¹, Maria Rita Gigante¹, Vivianaantonella Pacucci¹, Pier Giacomo Cerasuolo¹, Silvia Piunno¹, Francesco Cristiano¹, Cesare Gavotti¹, Pier Luigi Rizzuti¹, Rebecca Ventura¹, Jacopo Lenkowicz², Alfredo Cesario², Stefano Patarnello², Maria Antonietta D'Agostino¹. | ¹UOC di Reumatologia e Immunologia clinica - Fondazione Policlinico Universitario A. Gemelli IRCSS, UCSC, Roma, Italy; ²Fondazione Policlinico Universitario Agostino Gemelli IRCSS, Roma, Italy; ³AstraZeneca MIND, Milano, Italy.

Società Italiana di Reumatologia

DOI https://doi.org/10.4081/reumatismo.2025.2033
- 321 abstract views
PO:14:205 | Primary antiphospholipid antibody syndrome: association between new classification criteria manifestations and a higher-risk disease phenotype

Sara Ferrigno¹, Vittorio Forte², Marco Panetta¹, Sergio Lisena¹, Giorgia Ranucci², Luigi De Marco¹, Elisabetta Greco¹, Alberto Bergamini¹, Maria Sole Chimenti¹, Paola Conigliaro¹. | ¹Rheumatology, allergology and clinical immunology, Department of Systems Medicine, University of Rome Tor Vergata, Rome, Italy; ²Hematology, Department of Biomedicine and Prevention, University of Rome Tor Vergata, Rome, Italy.

Società Italiana di Reumatologia

DOI https://doi.org/10.4081/reumatismo.2025.2034
- 337 abstract views
PO:14:206 | Factors impacting subjective cognitive impairment in systemic lupus erythematosus patients: clearing away the lupus brain fog

Elisabetta Chessa¹, Marta Paola Pireddu², Fabio Congiu², Giulia Rizzo², Cristina Serafini³, Elena Ragusa², Alberto Cauli^1|2, Matteo Piga^1|2. | ¹SC Reumatologia- AOU Cagliari, Cagliari, Italy; ²Dipartimento di Scienze Mediche e Sanità Pubblica, Università di Cagliari, Cagliari, Italy; ³PO Sirai - Unità di Nefrologia e Dialisi, Carbonia (CA), Italy.

Società Italiana di Reumatologia

DOI https://doi.org/10.4081/reumatismo.2025.2035
- 406 abstract views
PO:14:207 | Nailfold capillaroscopy in systemic lupus erythematosus: microvascular alterations and their clinical relevance

Giulia Cassone¹, Filippo Santoro², Maria Grazia Malandra², Bruno Biasi², Elena Vanni², Caterina Vacchi¹, Alesandra Carobbio³, Dilia Giuggioli^1|2. | ¹Reumatologia, Azienda Ospedaliero-Universitaria Policlinico di Modena, Modena, Italy; ²Università di Modena e Reggio Emilia, Modena, Italy; ³Dipartimento di Scienze Mediche e Chirurgiche Materno-Infantili e dell'Adulto, Univeristà di Modena e Reggio Emilia, Modena, Italy.

Società Italiana di Reumatologia

DOI https://doi.org/10.4081/reumatismo.2025.2036
- 329 abstract views
PO:15:208 | Impact of disease control on organ damage accrual in patients with systemic lupus erythematosus with and extra-renal flares: a 12-month single-center longitudinal study

Giorgia Capozzo¹, Marco Oliva¹, Giancarlo Cascarano¹, Chiara Cardelli¹, Dina Zucchi¹, Chiara Stagnaro², Viola Signorini², Elena Elefante², Chiara Tani¹, Marta Mosca¹. | ¹Università di Pisa, Dipartimento di Medicina Clinica e Sperimentale, Pisa, Italy; ²Azienda Ospedaliero Universitaria Pisana, U.O. Reumatologia, Pisa, Italy.

Società Italiana di Reumatologia

DOI https://doi.org/10.4081/reumatismo.2025.2037
- 321 abstract views
PO:15:209 | Attainment of remission or lupus low disease activity state in single center Lupus Clinic

Paola Tedoldi^1|2, Silvia Ebe Lucia Della Pina^1|2, Claudia Barison^1|2, Chiara Orlandi^1|2, Cecilia Nalli¹, Micaela Fredi², Ilaria Cavazzana^1|2, Franco Franceschini^1|2 | ¹Rheumatology and Clinical Immunology Unit- ERN ReCONNET, ASST Spedali Civili of Brescia Brescia, Italy; ²Department of Clinical and Experimental Sciences, University of Brescia Brescia, Italy

Società Italiana di Reumatologia

DOI https://doi.org/10.4081/reumatismo.2025.2325
- 191 abstract views
PO:15:212 | Anifrolumab induces a rapid improvement in joint inflammation in Systemic Lupus Erythematosus patients: an ultrasonographic study

Valeria Moretti, Fulvia Ceccarelli, Claudia Ciancarella, Valerio Fiorilli, Francesca Romana Spinelli, Fabrizio Conti | Sapienza Università di Roma, Italy

Società Italiana di Reumatologia

DOI https://doi.org/10.4081/reumatismo.2025.2326
- 114 abstract views
PO:15:214 | Identification of SLE patients with high-levels Type 2 SLE through the polysymptomatic distress scale (PSD): correlations with other PROs and differences in clinical phenotypes in a multicentric cohort

Micaela Fredi^1|2, Giorgia Gozzoli^1|2, Federica Bonaso^1|2, Silvia Ebe Della Pina^1|2, Claudia Barison^1|2, Irene Lorenzini², Anna Mattiuzzo², Raffaele Pericotti², Marcelo Neto³, Sofia Avedo⁴, Clàudia Oliveira⁴, Luis Sousa Ines³, Franco Franceschini^1|2 | ¹Rheumatology and Clinical Immunology, ASST Spedali Civili of Brescia, ERN-ReCONNET Center, Brescia, Italy; ²Department of Clinical and Experimental Sciences, University of Brescia, Brescia, Italy; ³Rheumatology Department, Centro Hospitalar Universitário de Coimbra - ULS Coimbra, Coimbra, Portugal; ⁴Rheumatology Department, ULS Aveiro, Aveiro, Portugal

Società Italiana di Reumatologia

DOI https://doi.org/10.4081/reumatismo.2025.2327
- 113 abstract views
PO:15:215 | Evaluating the Prognostic Value of Modified NIH Indices and Total Renal Chronicity Score in Lupus Nephritis: a single center retrospective analysis

Alessandra Ida Celia¹, Andrea Ascione², Bruna Cerebelli², Martina Leopizzi², Cristiano Alessandri¹, Francesca Romana Spinelli¹, Fabrizio Conti¹ | ¹Reumaologia, Scienze Cliniche internistiche, anestesiologiche e cardiovascolari, Università La Sapienza di Roma, Italy; ²Anatomia patologica, Dipartimento di Scienze biotecnologiche medico-chirurgiche, Università La Sapienza di Roma, Italy

Società Italiana di Reumatologia

DOI https://doi.org/10.4081/reumatismo.2025.2328
- 105 abstract views
PO:15:216 | Safety and Efficacy of a single dose of Rituximab to manage Pregnancy-Related Severe Flare of Systemic Lupus Erythematosus: A Case Report

Eugenio Capparelli¹, Daniela Bompane¹, Eleonora Zaccara¹, Laura Castelnovo¹, Antonio Tamburello¹, Antonino Mazzone², Paola Faggioli¹ | ¹UOC Reumatologia, ASST Ovest Milanese, Legnano, Milano, Italy; ²UOC Medicina Interna, ASST Ovest Milanese, Legnano, Milano, Italy

Società Italiana di Reumatologia

DOI https://doi.org/10.4081/reumatismo.2025.2329
- 243 abstract views
PO:15:217 | Improved efficacy and safety outcomes in patients with systemic lupus erythematosus treated with belimumab vs. immunosuppressants, in addition to antimalarials and glucocorticoids: a post-hoc summary of five phase 3 trials

Mariele Gatto¹, Karen H. Costenbader², Andreas Schwarting³, Julia Hn Harris⁴, Ciara O'Shea⁵, Roger A. Levy⁶, Andrea Doria⁷ | ¹Centro Accademico Reumatologia, Dipartimento Scienze Cliniche Biologiche, Università degli Studi Torino, Osp. Mauriziano, Italy; ²Brigham and Women's Hospital, Divisione di Reumatologia, Infiammazione e Immunità, Harvard Medical School, Boston, MA, USA; ³Università Johannes Gutenberg di Mainz, Centro medico universitario, Germany; ⁴GSK, Immunologia Biostatistica London, UK; ⁵GSK, Global Medical Affairs Reumatologia, Dublin, Ireland; ⁶GSK, Global Medical Affairs Collegeville, PA, USA; ⁷Divisione di Reumatologia, Dipartimento di Medicina, Università di Padova, Italy

Società Italiana di Reumatologia

DOI https://doi.org/10.4081/reumatismo.2025.2160
- 328 abstract views
PO:15:218 | Evaluation of leukocyte expression of ecto-nucleotidase in patients with systemic lupus erythematosus

Luca Rapino¹, Simona Truglia¹, Fulvia Ceccarelli¹, Francesca Romana Spinelli¹, Silvia Mancuso¹, Giada La Spina¹, Hector Rincon Arvalo², Thomas Doerner², Ana Luisa Stefanski², Fabrizio Conti¹. | ¹La Sapienza Università di, Roma, - Dipartimento di Scienze Cliniche Internistiche Anestesiologiche e Cardiovascolare, Roma, Italy; ²Charité Universitätsmedizin - Department of Rheumatology and Clinical Immunology, Berlino, Germany.

Società Italiana di Reumatologia

DOI https://doi.org/10.4081/reumatismo.2025.2038
- 274 abstract views
PO:15:219 | Nailfold capillaroscopic abnormalities in systemic lupus erythematosus: comparison with healthy controls and clinical-immunological correlations. Preliminary data

Chiara Orlandi^1|2, Alessia Loda², Cesare Tomasi^1|2, Silvia Ebe Lucia Della Pina^1|2, Claudia Barison^1|2, Cecilia Nalli¹, Ilaria Cavazzana^1|2, Micaela Fredi^1|2, Franco Franceschini^1|2. | ¹Rheumatology and Clinical Immunology Unit - ERN ReCONNET , ASST Spedali Civili of Brescia, Brescia, Italy; ²Department of Clinical and Experimental Sciences, University of Brescia, Brescia, Italy.

Società Italiana di Reumatologia

DOI https://doi.org/10.4081/reumatismo.2025.2039
- 298 abstract views
PO:15:220 | Outcomes of extra renal flares in systemic lupus erythematosus: longitudinal analysis of a monocentric cohort

Marco Oliva¹, Giorgia Capozzo¹, Giancarlo Cascarano¹, Chiara Cardelli¹, Dina Zucchi¹, Angela Elia¹, Elena Elefante², Viola Signorini², Chiara Stagnaro², Chiara Tani¹, Marta Mosca¹. | ¹Rheumatology Unit, Department of Clinical and Experimental Medicine, University of Pisa, Pisa, Italy; ²Rheumatology Unit, AOUP, Pisa, Italy.

Società Italiana di Reumatologia

DOI https://doi.org/10.4081/reumatismo.2025.2040
- 323 abstract views
PO:15:221 | Proteins upregulated in thrombotic antiphospholipid syndrome link to platelet function in contrast with non-antiphospholipid-related thrombosis: insights from two systematic reviews

Silvia Mancuso¹, Claudia Ciancarella¹, Luca Rapino¹, Simona Truglia¹, Cristiano Alessandri¹, Fabrizio Conti¹. | ¹Dipartimento di Scienze Cliniche Internistiche, Anestesiologiche e Cardiovascolari - Rheumatology Unit, Sapienza Univers, Roma, Italy.

Società Italiana di Reumatologia

DOI https://doi.org/10.4081/reumatismo.2025.2041
- 309 abstract views
PO:15:222 | Post-hoc analysis of the BeRLiSS-JS registry: efficacy of belimumab on thrombocytopenia

Greta Hulej¹, Margherita Zen¹, Marisol Bracalenti¹, Francesca Bottazzi², Rossella De Angelis³, Giacomo Emmi⁴, Roberto Gerli⁵, Marcello Govoni⁶, Renato Lo Gullo⁷, Simone Negrini⁸, Luca Quartuccio⁹, Maurizio Rossini¹⁰, Carlo Salvarani¹¹, Paola Tomietto⁴, Angelo Vacca¹², Andrea Doria¹, Luca Iaccarino¹. | ¹Università degli Studi di Padova, Padova, Italy; ²Università degli Studi di Pavia, Pavia, Italy; ³Università Politecnica delle Marche, Ancona, Italy; ⁴Università degli Studi di Trieste, Trieste, Italy; ⁵Università degli Studi Perugia, Perugia, Italy; ⁶Università degli Studi di Ferrara, Ferrara, Italy; ⁷Università degli Studi di Catania, Catania, Italy; ⁸Università degli Studi di Torino, Torino, Italy; ⁹Università degli Studi di Udine, Udine, Italy; ¹⁰Università degli Studi di Verona, Verona, Italy; ¹¹Università degli Studi di Modena e Reggio Emilia, Modena, Italy; ¹²Università degli Studi di Bari .

Società Italiana di Reumatologia

DOI https://doi.org/10.4081/reumatismo.2025.2042
- 305 abstract views
PO:15:224 | Measuring disease activity in Systemic Lupus Erythematosus patients: SLE-DAS usefulness in real-life setting

Valeria Moretti, Fulvia Ceccarelli, Claudia Ciancarella, Cristina Garufi, Alessandra Ida Celia, Silvia Mancuso, Angelica Gattamelata, Simona Truglia, Francesca Romana Spinelli, Cristiano Alessandri, Fabrizio Conti | La sapienza Università di Roma, Italy

Società Italiana di Reumatologia

DOI https://doi.org/10.4081/reumatismo.2025.2330
- 106 abstract views
PO:16:225 | Belimumab in refractory and/or non-criteria manifestations of antiphospholipid syndrome: ad interim analysis on Quality-of-Life changes from the BLAST trial

Alessio Conti¹, Lois Ira Capulong¹, Irene Cecchi¹, Elena Rubini¹, Chiara Bova¹, Massimo Radin¹, Alice Barinotti¹, Beatrice Ala¹, Silvia Grazietta Foddai¹, Daniela Rossi¹, Roberta Fenoglio¹, Savino Sciascia¹ | ¹Centro di Eccellenza Universitario per le Malattie Nefrologiche, Reumatologiche e Rare, S.G.Bosco -ASL Città di Torino, Italy

Società Italiana di Reumatologia

DOI https://doi.org/10.4081/reumatismo.2025.2331
- 132 abstract views
PO:16:226 | Clinical Phenotypes of Systemic Lupus Erythematosus: An Exploratory Cluster Analysis in a Monocentric Cohort

Richard Borrelli¹, Stefania Nicola¹, Federica Corradi¹, Iuliana Badiu¹, Luca Lo Sardo¹, Marzia Boem¹, Valentina Marmora¹, Simone Negrini¹, Luisa Brussino¹ | ¹SCDU Immunologia e Allergologia, AO Mauriziano, Dipartimento di Scienze Mediche, Università degli Studi di Torino, Italy

Società Italiana di Reumatologia

DOI https://doi.org/10.4081/reumatismo.2025.2332
- 114 abstract views
PO:16:227 | Anifrolumab for Systemic Lupus Erythematosus: Preliminary Safety and Efficacy Findings from the Italian Experience

Paola Bizioli^1|2, Chiara Orlandi^1|2, Claudia Barison^1|2, Cesare Tomasi³, Alessia Caproli¹, Silvia Piantoni^1|2, Simona Signorini⁴, Emirena Garrafa⁴, Cecilia Nalli¹, Micol Frassi¹, Ilaria Cavazzana^1|2, Micaela Fredi^1|2, Franco Franceschini^1|2 | ¹Rheumatology and Clinical Immunology Unit - ERN ReCONNET, ASST Spedali Civili of Brescia, Italy; ²Department of Clinical and Experimental Sciences, University of Brescia, Italy; ³Department of Clinical and Experimental Sciences, University of Brescia, Italy; ⁴Laboratory of Clinical Chemistry, Department of Molecular and Translational Medicine, University of Brescia, Italy

Società Italiana di Reumatologia

DOI https://doi.org/10.4081/reumatismo.2025.2333
- 309 abstract views
PO:16:231 | Differential clinical features of systemic lupus erythematosus patients on biological therapies: insights from a monocentric cohort

Pietro Francesco Pilo, Elisa Bellis, Claudia Garulli, Claudio Cruciani, Marta Saracco, Claudia Lomater, Elena Marucco, Gloria Crepaldi, Valeria Data, Annamaria Iagnocco, Mariele Gatto. | Academic Rheumatology Centre, Department of Clinical and Biological Sciences, University of Turin, AO Mauriziano, Torino, Italy.

Società Italiana di Reumatologia

DOI https://doi.org/10.4081/reumatismo.2025.2043
- 317 abstract views
PO:16:232 | Belimumab step-down dose spacing in patients with systemic lupus erythematosus in persistent clinical remission: experience from a multicentric cohort

Alice Bartoletti¹, Laura Giudice¹, Lorenza Maria Argolini^1|2, Giuseppe Alvise Ramirez³, Luca Moroni³, Tommaso Schioppo⁴, Chiara Bellocchi^5|6, Annalaura Fasiello⁶, Lorenzo Beretta⁶, Lorenzo Dagna³, Roberto Caporali¹, Maria Gerosa¹. | ¹UO Clinica Reumatologica, ASST Gaetano Pini CTO, Milano, Italy; ²UOC Medicina fisica e riabilitazione specialistica, ASST Gaetano Pini CTO, Milano, Italy; ³Unit of Immunology, Rheumatology, Allergy and Rare Diseases, IRCCS San Raffaele Hospital, Vita-Salute San Raffa Milano Italy; ⁴Medicina Generale II, Servizio di Reumatologia, Ospedale San Paolo, ASST Santi Paolo Carlo, Milano, Italy; ⁵Department of Clinical Sciences and Community Health, University of Milan, Dipartimeto di Eccellenza 2023-2027, Milano, Italy; ⁶Referral Centre for Systemic Autoimmune DIseases, Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico, Milano, Italy

Società Italiana di Reumatologia

DOI https://doi.org/10.4081/reumatismo.2025.2044
- 443 abstract views
PO:16:233 | Efficacy of voclosporin on nephritis in patients with variable gain of function of TLR7 affected by lupus: clinical case

Veronica Spedicato¹, Laura Coladonato¹, Marco Fornaro¹, Marlea Lavista¹, Daniele Sabella¹, Marco Capodiferro¹, Maria Morrone¹, Crescenzio Scioscia¹, Giuseppe Lopalco¹, Florenzo Iannone¹ | ¹Unit of Rheumathology, Department of Precision and Regenerative Medicina, Area Jonica^J, University of Bari, Italy

Società Italiana di Reumatologia

DOI https://doi.org/10.4081/reumatismo.2025.2161
- 335 abstract views
PO:16:234 | Differential efficacy of induction treatments for lupus nephritis at onset and relapses: an observational study

Giuseppe Alvise Ramirez^1|2, Gabriele D Gallina¹, Chiara Calabrese^1|2, Serena Nannipieri^1|2, Marta Calatroni^3|4, Francesco Reggiani^3|4, Giovanni Benanti¹, Enrica Paola Bozzolo¹, Raffaele Ceniccola², Luca Moroni^1|2, Marco Matucci-Cerinic^1|2, Gabriella Moroni^3|4, Lorenzo Dagna^1|2 | ¹IRCCS San Raffaele Hospital, Unit of Immunology, Rheumatology, Allergy and Rare Diseases Milan, Italy; ²Vita- Salute San Raffaele University Milan, Italy; ³IRCCS Humanitas Research Hospital, Nephrology and Dialysis Division Rozzano, Milan, Italy; ⁴Humanitas University, Department of Biomedical Sciences Rozzano, Milan, Italy

Società Italiana di Reumatologia

DOI https://doi.org/10.4081/reumatismo.2025.2334
- 193 abstract views
PO:16:235 | Anifrolumab in systemic lupus erythematosus: real-life experience of a single-center cohort

Filippo Vesentini¹, Luca Iaccarino¹, Federico Arru², Greta Hulej¹, Anna Giorgia Osele¹, Noemi Merra¹, Davide Ragno¹, Andrea Doria¹, Margherita Zen¹ | ¹UOC Reumatologia, Dipartimento di Medicina DIMED, Università degli Studi di Padova; ²UO Medicina, ASL 3 Nuoro, Italy

Società Italiana di Reumatologia

DOI https://doi.org/10.4081/reumatismo.2025.2162
- 546 abstract views
PO:16:236 | Achieving a low disease activity state with a corticosteroid dose of 5 mg or less: observational study with anifrolumab in patients with systemic lupus erythematosus in Italy

Alessandra Bortoluzzi¹, Fulvia Ceccarelli², Fabio Leo³, Paola Roccatagliata³, Chiara Tani⁴, Margherita Zen⁵ | ¹Azienda Ospedaliera Universitaria Sant' Anna di Cona, Università di Ferrara Italy; ²Unità di Reumatologia, Università Sapienza Roma Italy; ³AstraZeneca S.p.a. Milano Italy; ⁴Università di Pisa e Azienda Ospedaliero Universitaria Pisana, Pisa Italy; ⁵Dipartimento di Medicina DIMED , Divisione di Reumatologia, Università di Padova, Italy

Società Italiana di Reumatologia

DOI https://doi.org/10.4081/reumatismo.2025.2163
- 284 abstract views
PO:16:238 | Cardiovascular risk in systemic lupus erythematosus patients: comparison among Framingham Score, QRISK3, and SLECRE

Francesca Vignoni^1|2, Serena Iodice², Cesare Tomasi², Chiara Orlandi^1|2, Eleonora Pedretti¹, Micaela Fredi², Franco Franceschini^1|2, Ilaria Cavazzana^1|2. | ¹Rheumatology and Clinical Immunology Unit - ERN ReCONNET, ASST Spedali Civili of Brescia, Brescia, Italy; ²Department of Clinical and Experimental Sciences, University of Brescia, Brescia, Italy.

Società Italiana di Reumatologia

DOI https://doi.org/10.4081/reumatismo.2025.2045
- 305 abstract views
PO:16:240 | Systemic Lupus Erythematosus Presenting as End-Stage Liver Disease: A Case Report and Literature Review

Annamaria Tiso¹, Stefania Caccavelli¹, Giuseppina Caroppi¹, Candida Tarullo¹, Gaetano Serviddio¹ | ¹Policlinico Riuniti Foggia, Italy

Società Italiana di Reumatologia

DOI https://doi.org/10.4081/reumatismo.2025.2335
- 261 abstract views
PO:16:241 | Prevalence and associated factors of premature ovarian insufficiency in women with systemic lupus erythematosus: the role of human herpesviruses HHV-7 and HHV-8

Margherita Rizzo¹, Francesca Ruffilli¹, Silvia Beltrami², Daria Bortolotti², Roberta Rizzo², Carlo Garaffoni¹, Ettore Silvagni¹, Marcello Govoni¹, Alessandra Bortoluzzi¹ | ¹UOC Reumatologia, Dipartimento di Scienze Mediche, Università di Ferrara e Azienda Ospedaliero-Universitaria S. Anna, Ferrara; ²Dipartimento di Scienze Chimiche, Farmaceutiche e Agrarie, Ferrara Italy

Società Italiana di Reumatologia

DOI https://doi.org/10.4081/reumatismo.2025.2164
- 331 abstract views
PO:17:248 | Prevention of human papillomavirus infection in women with systemic lupus erythematosus: a single-center cross-sectional study

Clizia Gagliardi¹, Maria Chiara Gerardi¹, Bianca Lucia Palermo¹, Giulia Carrea¹, Maria Di Cicco¹, Elena Manna¹, Giulia Segatto¹, Antonella Adinolfi¹, Laura Belloli¹, Cinzia Casu¹, Silvia Cavalli¹, Davide Antonio Filippini¹, Matteo Longhi¹, Gabriella Maioli¹, Martina Schettino¹, Nicola Ughi¹, Elisa Verduci¹, Arianna Bertolucci¹, Lara Buffa¹, Giulia Buonsante¹, Claudia Cordini¹, Eleonora Giacobbe¹, Francesco Molica Colella¹, Oscar Epis¹ | ¹ASST Grande Ospedale Metropolitano Niguarda, Milano, Italy

Società Italiana di Reumatologia

DOI https://doi.org/10.4081/reumatismo.2025.2165
- 352 abstract views
PO:17:250 | Effectiveness and safety of the recombinant zoster vaccine in patients ≥18 years of age with systemic lupus

Giulia Boschi¹, Sheryl A. Kluberg², Sophie E. Mayer², O'Mareen Spence³, Driss Oraichi³, Harry Seifert³, Omar Ali³, Huifeng Yun³, Andrew L. Simon⁴, Jenice S. Ko⁴, Caroline Hugh⁴, Meg Her⁴, Kathleen Shattuck⁴, Richard Platt², Aziza Jamal-Allial⁵, Djeneba Audrey Djibo⁶, Kimberly Daniels⁵, Qianli Ma⁷, Cheryl N. Mcmahill-Walraven⁶, Rachel P. Ogilvie⁸, Kristin Palmsten⁹, Mano Selvan⁷, Najat Ziyadeh⁸, Alexis Ogdie¹⁰, Michael George¹⁰ | ¹GSK Verona Italy; ²Harvard Medical School and the Department of Population Medicine, Harvard Pilgrim Health Care Institute, Boston; ³GSK Rockville; ⁴Department of Population Medicine, Harvard Pilgrim Health Care Institute, Boston; ⁵Carelon Research, Wilmington; ⁶CVS Health, Blue Bell; ⁷Humana Healthcare Research, Louisville; ⁸OptumInsight Life Sciences, Boston; ⁹HealthPartners Institute, Bloomington; ¹⁰University of Pennsylvania, Philadelphia, USA

Società Italiana di Reumatologia

DOI https://doi.org/10.4081/reumatismo.2025.2166
- 319 abstract views
PO:17:252 | The choice between belimumab and anifrolumab: analysis of a monocentric cohort

Fabio Congiu¹, Elisabetta Chessa², Giulia Rizzo¹, Elena Ragusa¹, Marta Paola Pireddu¹, Alessandra Oliva¹, Marianna Salis¹, Mattia Congia², Maria Maddalena Angioni¹, Micaela Rita Naitza¹, Alberto Floris², Alberto Cauli^1|2, Matteo Piga^1|2 | ¹AOU e Università degli studi di Cagliari; ²SC Reumatologia PO Duilio Casula, Cagliari, Italy

Società Italiana di Reumatologia

DOI https://doi.org/10.4081/reumatismo.2025.2167
- 342 abstract views
PO:17:253 | Unveiling the gap: a multicenter study on factors driving patient-physician discrepancies in assessing disease activity in systemic lupus erythematosus

Giorgia Ingrid Gozzoli¹, Micaela Fredi¹, Federica Bonaso¹, Silvia Ebe Lucia Della Pina¹, Claudia Barison¹, Irene Lorenzini⁴, Raffaele Pericotti⁴, Anna Mattiuzzo⁴, Marcelo Neto², Sofia Azevedo³, Cláudia Oliveira³, Cesare Tomasi⁴, Luís Sousa Inês², Franco Franceschini¹. | ¹Rheumatology and Clinical Immunology Unit, ASST Spedali Civili of Brescia, Brescia, Italy; ²Rheumatology Department, Centro Hospitalar Universitário de Coimbra - ULS Coimbra, Coimbra, Portugal; ³Rheumatology Department, ULS Aveiro, Aveiro, Portugal; ⁴Department of Clinical and Experimental Sciences, University of Brescia, Brescia, Italy.

Società Italiana di Reumatologia

DOI https://doi.org/10.4081/reumatismo.2025.2046
- 341 abstract views
PO:17:254 | Systemic lupus erythematosus with pulmonary involvement: clinical insights from an Albanian cohort

Arbi Pecani¹, Arian Mezini², Loreta Karaulli², Laert Gjati², Silvana Bala² | ¹Reumatologia, Dipartimento di Medicina Interna, Università di Medicina di Tirana, Ospedale Universitario Shefqet Ndroqi, Tirana; ²Pneumologia, Dipartimento di Medicina Respiratoria, Ospedale Universitario Shefqet Ndroqi, Tirana, Albania

Società Italiana di Reumatologia

DOI https://doi.org/10.4081/reumatismo.2025.2168
- 350 abstract views
PO:17:255 | Efficacy and safety of voclosporin in the management of lupus nephritis: a case series

Alessandra Oliva¹, Elisabetta Chessa², Marta Paola Pireddu¹, Marianna Salis¹, Giulia Rizzo¹, Fabio Congiu¹, Elena Ragusa¹, Antonello Pani^3|4, Alberto Cauli^1|2, Nicola Lepori^3|4, Matteo Piga^1|2 | ¹UOC Reumatologia, Dipartimento di Scienze Mediche e Salute Pubblica, Università degli Studi di Cagliari; ²UOC Reumatologia, AOU Cagliari; ³SC Nefrologia e Dialisi, Università degli Studi di Cagliari; ⁴SC Nefrologia e Dialisi, Azienda Ospedaliera Brotzu, Cagliari, Italy

Società Italiana di Reumatologia

DOI https://doi.org/10.4081/reumatismo.2025.2169
- 340 abstract views
PO:17:259 | Anifrolumab: a new management of SLE

Giorgia Montozzi¹, Chiara Cocco¹, Ramona Santangeli¹, Lucia Gamba¹, Paola Fioretti¹, Letizia Curina¹, Chiara Guidoni¹, Edoardo Cipolletta³, Gianluca Moroncini² | ¹Scuola di Specializzazione in Medicina Interna, Università Politecnica delle Marche Ancona, Italy; ²Department of Clinical and Molecular Sciences, Università Politecnica delle Marche Ancona, Italy; ³Rheumatology Unit, Department of Clinical and Molecular Sciences , Università Politecnica delle Marche Ancona, Italy

Società Italiana di Reumatologia

DOI https://doi.org/10.4081/reumatismo.2025.2336
- 252 abstract views
PO:18:264 | Anifrolumab in Systemic Lupus Erythematosus: Bridging Clinical Trial Data with Real-World Evidence

Giulia Cassone², Filippo Santoro¹, Caterina Vacchi², Dilia Giuggioli², Chiara Cabassi¹ | ¹UOC Reumatologia, AOU Policlinico di Modena, Università degli studi di Modena e Reggio Emilia Modena e Reggio Emilia, Italy; ²UOC Reumatologia, AOU Policlinico di Modena Modena, Italy

Società Italiana di Reumatologia

DOI https://doi.org/10.4081/reumatismo.2025.2337
- 247 abstract views
PO:18:268 | Voclosporin as a Steroid-Sparing Agent in Lupus Nephritis Complicated by Central Serous Chorioretinopathy: A Case Report

Irene Genovali^1|2, Sebastiano Lorusso², Damiano Currado^1|2, Letizia Pia Di Corcia¹, Ludovica Lamberti¹, Annalisa Marino², Antonio Orlando¹, Maria Quadrini¹, Marta Vadacca², Marta Vomero¹, Luca Navarini^1|2, Roberto Giacomelli^1|2 | ¹Rheumatology and Clinical Immunology, Department of Medicine, University of Rome Campus Biomedico, School of Medicine Rome, Italy; ²Clinical and Research Section of Rheumatology and Clinical Immunology Fondazione Policlinico Campus Biomedico Rome, Italy

Società Italiana di Reumatologia

DOI https://doi.org/10.4081/reumatismo.2025.2338
- 252 abstract views
PO:18:271 | Managing concomitant sle and psoriasis: the role of anifrolumab in a clinical case

Angela Carenza¹, Liliana Dinoia², Sergio De Gioia², Federica Gatti¹, Teresa Caferri¹, Lucia Cristiana Colaprico¹, Angelica Napoletano¹, Giuseppe Lopalco¹, Florenzo Iannone¹. | ¹Rheumatology Unit, University of Bari, Department of Precision and Regenerative Medicine, Jonian area ^DiMePRe-J, Bari, Italy; ²Azienda Sanitaria Locale di Taranto, presidio ospedaliero SS. Annunziata, Unità Operativa di Reumatologia, Taranto, Italy.

Società Italiana di Reumatologia

DOI https://doi.org/10.4081/reumatismo.2025.2047
- 529 abstract views
PO:18:276 | Use of anifrolumab in the treatment of difficult-to-treat manifestations in systemic lupus erythematosus

Antonella Grimaldi¹, Giuseppe Alessandrini², Laura Quarta¹, Maria Rita Ricciardi¹, Daniela Costanza¹, Clara Minerba¹, Eugenio Quarta¹ | ¹UOC Reumatologia Verona; ²Specialista Dermatologo in Libera Professione, Italy

Società Italiana di Reumatologia

DOI https://doi.org/10.4081/reumatismo.2025.2170
- 368 abstract views
PO:18:277 | Clinical case report of the management of a patient suffering from systemic lupus erythematosus and associated polyneuropathy

Davide Murgia¹, Elena Marazzi¹, Rosetta Vitetta¹, Guido Rovera¹. | ¹ASLVC SSD reumatologia, Ospedale sant'Andrea Vercelli, Vercelli, Italy.

Società Italiana di Reumatologia

DOI https://doi.org/10.4081/reumatismo.2025.2048
- 295 abstract views
PO:19:279 | Predictors of proteinuria, amyloidosis and kidney failure in familial Mediterranean fever: data from the International AIDA Network Registry

Jessica Sbalchiero¹, Antonio Vitale¹, Valeria Caggiano¹, Abdurrahman Tufan², Ezgi Batu³, Gaafar Ragab⁴, Seza Ozen³, Jurgen Sota¹, Carla Gaggiano¹, Ali Sahin⁵, Petros Sfikakis⁶, Francesca Li Gobbi⁷, Giacomo Emmi⁸, Jose Rodriguez⁹, Piero Ruscitti¹⁰, Paolo Sfriso¹¹, Ewa Szewczyk¹², Giuseppe Lopalco¹³, Alberto Balistreri¹⁴, Claudia Fabiani¹⁵, Bruno Frediani¹, Luca Cantarini¹ | ¹Department of Medical Sciences, Surgery and Neurosciences, University of Siena, Siena, Italy; ²Department of Internal Medicine, Division of Rheumatology, Gazi University Hospital Ankara, Turkey; ³Division of Pediatric Rheumatology, Department of Pediatrics, Hacettepe University School of Medicine Ankara, Turkey; ⁴Internal Medicine Department, Rheumatology and Clinical Immunology Unit, Faculty of Medicine, Cairo University Giza, Egypt; ⁵Division of Rheumatology, Department of Internal Medicine, Sivas Cumhuriyet University Medical Faculty Sivas, Turkey; ⁶Joint Academic Rheumatology Program, Medical School, National and Kapodistrian University of Athens Athens, Greece; ⁷Rheumatology Unit, Hospital S. Giovanni di Dio, Azienda USL-Toscana Centro Florence, Italy; ⁸Clinical Medicine and Rheumatology Unit, Cattinara University Hospital Trieste, Italy; ⁹Department of Autoimmune Diseases, Institut Investigacions Biomediques August Pi I Sunyer, University of Barcelona Barcelona Spain; ¹⁰Rheumatology Unit, Department of Biotechnological and Applied Clinical Sciences, University of L'Aquila, L'Aquila, Italy; ¹¹Rheumatology Unit, Department of Medicine, University of Padua Padua, Italy; ¹²7Department of Internal Medicine, Pneumonology, Allergology, Clinical Immunology and Rare Diseases, Military Institute o Warsaw, Poland; ¹³Department of Precision and Regenerative Medicine and Ionian Area DiMePRe-J Policlinic Hospital, University of Bari Bari, Italy; ¹⁴Bioengineering and Biomedical Data Science Lab, Department of Medical Biotechnologies, University of Siena Siena, Italy; ¹⁵Ophthalmology Unit, Department of Medicine, Surgery and Neurosciences, University of Siena Siena, Italy

Società Italiana di Reumatologia

DOI https://doi.org/10.4081/reumatismo.2025.2339
- 207 abstract views
PO:19:281 | Mitochondrial dysfunction in Still’s disease: a preliminary analysis of mtDNA copy number and TFAM expression

Ludovica Manisera¹, Francesca Giansanti², Andrea Latini³, Francesca Lotito⁴, Serena Colafrancesco⁵, Angelica Gattamelata⁶, Fabrizio Conti⁷, Cinzia Ciccacci⁸, Roberta Priori⁹ | ^1|6|7|9La Sapienza, Roma; ^2|3|4|8Unicamillus, Roma; ⁵Humanitas, Milano, Italy

Società Italiana di Reumatologia

DOI https://doi.org/10.4081/reumatismo.2025.2171
- 312 abstract views
PO:19:283 | Hospitalization profile and complications in patients with adult-onset Still’s disease: results from a retrospective study of 74 cases

Chiara Calabrese¹, Alessandro Tomelleri^1|2, Corrado Campochiaro^1|2, Nicola Farina², Elena Baldissera², Marco Matucci-Cerinic^1|2, Lorenzo Dagna^1|2 | ¹Libera Università Vita-Salute San Raffaele, Milano; ²Unità di Immunologia, Allergologia e malattie rare, IRCCS San Raffaele, Milano, Italy

Società Italiana di Reumatologia

DOI https://doi.org/10.4081/reumatismo.2025.2172
- 390 abstract views
PO:19:284 | Use of anakinra during pregnancy and breastfeeding in women with recurrent pericarditis: a case series

Lucia Trotta¹, Marco Quartarone¹, Francesco Cavaleri¹, Ruggiero Mascolo¹, Massimo Imazio³, Vartan Mardygan², Andreja Cerne Cercek⁴, Anne-Marie Claveau², Ludovico Luca Sicignano⁵, Massimo Pancrazi¹, Alida Caforio⁶, Andrea Silvio Giordani⁶, Serdal Ugurlu⁷, Alessandro Andreis⁸, Valentino Collini³, Enrico Tombetti⁹, Antonio Brucato⁹ | ¹Department of Internal Medicine, ASST Fatebenefratelli-Sacco, Milan, Italy; ²Division of Cardiology, Department of Medicine, Jewish General Hospital, Montréal, Québec, Canada; ³Cardiology, Cardiothoracic Department, University Hospital Santa Maria della Misericordia, Udine, Italy; ⁴Department of Cardiology, University Medical Centre Ljubljana, Ljubljana, Slovenia; ⁵Fondazione Policlinico Universitario Agostino Gemelli IRCCS, Rome, Italy; ⁶Division of Cardiology, Centro Gallucci, University of Padova-Policlinico, Padova, Italy; ⁷Division of Rheumatology, Department of Internal Medicine, Istanbul University-Cerrahpasa, Istanbul, Turkey; ⁸University Cardiology, A.O.U. Città della Salute e della Scienza di Torino, Torino, Italy; ⁹Department of Biomedical and Clinical Sciences, Fatebenefratelli Hospital, University of Milan, Milan, Italy

Società Italiana di Reumatologia

DOI https://doi.org/10.4081/reumatismo.2025.2340
- 215 abstract views
PO:19:286 | Genetic testing reveals an unexpected case of mevalonate kinase deficiency in a 37-year-old patient with AA renal amyloidosis and good response to colchicine

Francesca Crisafulli¹, Paolo Airò², Federica Mescia³, Gianmarco Lugli³, Gianfranco Savoldi⁴, Claudia Izzi^3|5, Federico Alberici³, Marco Cattalini⁶, Franco Franceschini¹, Micol Frassi². | ¹Rheumatology and Clinical Immunology Unit, ASST Spedali Civili and University of Brescia, Brescia, Italy; ²Rheumatology and Clinical Immunology Unit, ASST Spedali Civili of Brescia, Brescia, Italy; ³U.O Nefrologia, ASST Spedali Civili di Brescia e Università degli Studi di Brescia, Brescia, Italy; ⁴Medical genetics Laboratory, Laboratory Department ASST Spedali Civili di Brescia, Brescia, Italy; ⁵Struttura Complessa di Genetica Clinica, ASST Spedali Civili di Brescia, Brescia, Italy; ⁶Pediatrics Clinic, University of Brescia and ASST Spedali Civili of Brescia, Brescia, Italy.

Società Italiana di Reumatologia

DOI https://doi.org/10.4081/reumatismo.2025.2049
- 340 abstract views
PO:19:287 | Cardiac involvement in Still’s disease: a challenge in differential diagnosis

Ludovica Manisera¹, Martina Dodaro², Giuseppe Norcia³, Angelica Gattamelata⁴, Nicola Galea⁵, Concetta Torromeo⁶, Gaetano Tanzilli⁷, Fabrizio Conti⁸, Roberta Priori⁹ | ¹Dipartimento di Scienze Cliniche, Internistiche, Anestesiologiche e Cardiovascolari, Università degli Studi di Roma La Sapienza, Roma; ²Dipartimento di Medicina Traslazionale e di Precisione, Università degli Studi di Roma La Sapienza, Roma; ³Dipartimento di Medicina Molecolare, Università degli Studi di Roma La Sapienza, Roma, Italy

Società Italiana di Reumatologia

DOI https://doi.org/10.4081/reumatismo.2025.2173
- 330 abstract views
PO:20:002 | Respiratory function tests predict bone mineral density in autoimmune rheumatic disease patients

Andrea Zoli¹, Panagiotis Garantziotis², Sebastian Böltz², Janina Auth², Sara Bayat², Jule Taubmann², Anna-Maria Liphardt², Maria Antonietta D'Agostino¹, Christina Bergmann², Georg Schett². | ¹Division of Rheumatology, Fondazione Policlinico Universitario A. Gemelli, IRCCS, Università Cattolica del Sacro Cuore, Roma, Italy; ²Department of Medicine 3, Rheumatology and Immunology, Friedrich Alexander Universität FAU, Erlangen, Germany.

Società Italiana di Reumatologia

DOI https://doi.org/10.4081/reumatismo.2025.2050
- 299 abstract views
PO:20:003 | Romosozumab effect on neutrophil-to-lymphocyte ratio in post-menopausal women at high risk of fracture

Giorgia Scagliosi¹, Mariana Diaz Lopez¹, Martina Teoni¹, Francesco Pollastri¹, Anna Piccinelli¹, Camilla Benini¹, Valeria Messina¹, Emma Pasetto¹, Davide Gatti¹, Ombretta Viapiana¹, Maurizio Rossini¹, Giovanni Adami¹. | ¹Università di Verona, Dipartimento di Medicina, Verona, Italy; ²Università di Verona, Dipartimento di Medicina, Verona, Italy; ³Università di Verona, Dipartimento di Medicina, Verona, Italy; ⁴Università di Verona, Dipartimento di Medicina, Verona, Italy; ⁵Università di Verona, Dipartimento di Medicina, Verona, Italy; ⁶Università di Verona, Dipartimento di Medicina, Verona, Italy; ⁷Università di Verona, Dipartimento di Medicina, Verona, Italy; ⁸Università di Verona, Dipartimento di Medicina, Verona, Italy; ⁹Università di Verona, Dipartimento di Medicina, Verona, Italy; ¹⁰Università di Verona, Dipartimento di Medicina, Verona, Italy; ¹¹Università di Verona, Dipartimento di Medicina, Verona, Italy; ¹²Università di Verona, Dipartimento di Medicina, Verona, Italy.

Società Italiana di Reumatologia

DOI https://doi.org/10.4081/reumatismo.2025.2051
- 331 abstract views
PO:20:004 | Increase in serum Dkk1 levels attenuates the anabolic response to romosozumab in postmenopausal osteoporosis

Giovanni Adami¹, Filippo Montanari¹, Angelo Fassio¹, Francesco Pollastri¹, Anna Piccinelli¹, Davide Gatti¹, Ombretta Viapiana¹, Maurizio Rossini¹. | ¹Università degli Studi di Verona, Verona, Italy.

Società Italiana di Reumatologia

DOI https://doi.org/10.4081/reumatismo.2025.2052
- 293 abstract views
PO:20:005 | Sarcopenia and fracture risk in rheumatoid arthritis: correlation between SACR-F and fragility score measured by radiofrequency echographic multi-spectrometry

Sara Torracchi¹, Pamela Bernardini¹, Daniela Melchiorre¹, Bianca Bossi¹, Dorilda Zeka¹, Francesca Nacci¹, Lorenzo Tofani¹, Serena Guiducci¹ | ¹SOD Reumatologia, Dipartimento di Medicina Sperimentale e Clinica, Università degli Studi di Firenze, Italy

Società Italiana di Reumatologia

DOI https://doi.org/10.4081/reumatismo.2025.2174
- 330 abstract views
PO:20:006 | Efficacy of denosumab in glucocorticoid-induced osteoporosis patients with prior exposure to intravenous aminobisphosphonates

Kiren Khalid¹, Alessandro Giollo¹, Mariangela Salvato¹, Francesca Frizzera¹, Lorenzo Di Luozzo¹, Bernd Raffeiner², Andrea Doria¹ | ¹Rheumatology Unit, Department of Medicine - DIMED, University of Padova, Padova, Italy; ²Department of Rheumatology, Bolzano Central Hospital, Bolzano, Italy

Società Italiana di Reumatologia

DOI https://doi.org/10.4081/reumatismo.2025.2341
- 140 abstract views
PO:20:007 | Mind the rebound: ctx dynamics after denosumab discontinuation and zoledronate rescue in patients with postmenopausal osteoporosis or with cancer treatment-induced bone loss

Federico Aldegheri¹, Francesca Ruzzon¹, Matteo Appoloni¹, Giovanni Adami¹, Davide Gatti¹, Maurizio Rossini¹, Angelo Fassio¹, Ombretta Viapiana¹ | ¹Università di Verona, Italy

Società Italiana di Reumatologia

DOI https://doi.org/10.4081/reumatismo.2025.2342
- 257 abstract views
PO:20:010 | Coordinated outpatient pathway for osteoporosis: a new organizational model for osteoporosis management

Domenico Birra¹, Ornella Romano², Vincenza Sara Suppa², Mariavittoria Guerra¹, Carmine Fierarossa¹, Benedetta Tartaglia¹, Antonietta De Sena¹, Fabio Granato Corigliano¹, Serena Ippolito², Vincenzo Nuzzo¹ | ¹UOC Medicina Generale, P.O. Ospedale del Mare, Asl Napoli 1 Centro; ²U.O.S.D. Malattie Endocrine del ricambio e della nutrizione, P.O. Ospedale del Mare, Asl Napoli 1 Centro, Italy

Società Italiana di Reumatologia

DOI https://doi.org/10.4081/reumatismo.2025.2175
- 311 abstract views
PO:20:011 | Suspected tumor-induced osteomalacia in a patient with polymyalgia rheumatica and persistent hyperphosphaturic hypophosphatemia

Andrea Faggiano^1|2, Francesco Goatelli^1|2, Lucia Dardani², Carlo Salvarani³ | ¹Unit of Rheumathology, Department of Precision and Regenerative Medicina, Area Jonica, University of Bari; ²Scuola di Specializzaione in Reumatologia, Università degli Studi di Modena e Reggio Emilia, Modena, Italy; ³Direttore SOC Reumatologia, IRCCS Arcispedale Santa Maria Nuova, AUSL REGGIO EMILIA, Italy

Società Italiana di Reumatologia

DOI https://doi.org/10.4081/reumatismo.2025.2176
- 368 abstract views
PO:20:012 | Inflammatory markers and nutritional status in patients with osteoporotic fractures: preliminary analysis of a pilot study

Domenico Birra¹, Manuela Maione², Carolina Bologna¹, Carmela Pierce², Paolo Tirelli¹, Gianluigi Cuomo¹, Carolina Sepe², Pasquale Madonna¹, Claudio De Luca¹, Federica Coretti², Vincenzo Nuzzo¹ | ¹S.C. Reumatologia, ASST Grande Ospedale Metropolitano Niguarda, Milano, Italy; ²U.O.S.D. Malattie Endocrine del ricambio e della nutrizione - P. O. Ospedale del Mare - Asl Napoli 1 centro, Napoli, Italy

Società Italiana di Reumatologia

DOI https://doi.org/10.4081/reumatismo.2025.2177
- 301 abstract views
PO:20:014 | Post-partum osteoporosis: severe clinical presentation in absence of known risk factors

Domenico Birra¹, Ludovica Frances Grasso², Vittoria Gammaldi¹, Antonietta De Sena¹, Carmine Pio Petrosino², Rosalia Boccia², Gabriella Oliva¹, Vincenzo Nuzzo¹ | ¹Dipartimento di Scienze Cliniche Internistiche, Anestesiologiche e Cardiovascolari, Sapienza Università di Roma; ²Istituto Superiore di Sanità, Roma

Società Italiana di Reumatologia

DOI https://doi.org/10.4081/reumatismo.2025.2178
- 325 abstract views
PO:21:018 | The role of rheumatologists in the diagnosis and monitoring of Whipple's disease

Mariangela Salvato¹, Alessandro Giollo¹, Marco Cola², Francesca Frizzera¹, Kiren Khalid¹, Lorenzo Di Luozzo¹, Annamaria Cattelan², Andrea Doria¹ | ¹UOC Reumatologia, AOUI Padova, Italy; ²UOC Malattie infettive, AOUI Padova, Italy

Società Italiana di Reumatologia

DOI https://doi.org/10.4081/reumatismo.2025.2343
- 209 abstract views
PO:21:019 | Clinical phenotypes in IgG4-related disease: ACR/EULAR classification and practical limitations

Mattia Caliste¹, Flavia D'Auria², Linda Mastromanno¹, Francesca Carfora², Carla Giordano³, Cristiano Alessandri¹, Marcella Visentini², Fabrizio Conti¹, Roberta Priori^1|4 | ¹Dipartimento Scienze Cliniche Internistiche, Anestesiologiche e Cardiovascolari, Sapienza Università di Roma; ²Dipartimento Medicina Traslazionale e di Precisione, Sapienza Università di Roma; ³Dipartimento Scienze Radiologiche, Oncologiche e Anatomo-patologiche, Sapienza Università di Roma; ⁴Saint Camillus International University of Health Science, UniCamillus, Roma, Italy

Società Italiana di Reumatologia

DOI https://doi.org/10.4081/reumatismo.2025.2179
- 347 abstract views
PO:21:021 | The eyes tell the story: a clinical case of Rosah syndrome

Nicolò Sabbion¹, Sofia Vitale¹, Claudia Balicchia¹, Barbara Troise¹, Francesca Mascia¹, Eleonora Bassanello², Jacopo Croce², Federica Maiolini², Filippo Mazzi², Elisa Tinazzi², Francesca Bosello¹, Simonetta Friso¹, Lucia De Franceschi¹ | ¹Università degli Studi di Verona; ²Azienda Ospedaliera Universitaria Integrata, Verona, Italy

Società Italiana di Reumatologia

DOI https://doi.org/10.4081/reumatismo.2025.2180
- 522 abstract views
PO:21:026 | Identifying patient profiles to personalize care and improve quality of life in italian EGPA patients

Francesca Torracca¹, Roberto Padoan², Giacomo Emmi^3|4, Lara Bernardi⁵, Maria Rosaria Mollo⁵, Omar Shalby⁵, Fabio Tedone⁶, Davide Cafiero⁶, Eugenia Durante¹ | ¹APACS APS ETS - Associazione Pazienti Sindrome di Churg Strauss EGPA Arosio, Italy; ²Rheumatology Unit, Department of Medicine DIMED, University of Padua, Italy; ³Department of Medical, Surgical and Health Sciences, University of Trieste, Italy; ⁴Clinical Medicine Rheumatology Unit, Cattinara University Hospital, Trieste, Italy; ⁵GlaxoSmithKline Medical Department Verona, Italy; ⁶Helaglobe SRL Firenze, Italy

Società Italiana di Reumatologia

DOI https://doi.org/10.4081/reumatismo.2025.2344
- 138 abstract views
PO:21:028 | A difficult case of VEXAS syndrome: management of myelodysplastic syndrome associated with systemic inflammation and infectious complications

Sandra Lombardi¹, Monica Regis¹, Stefano De Luca¹, Monica Poiani², Rossella Stella², Elisa Lucchini², Francesco Zaja², Fabio Fiammengo¹ | ¹SC Medicina Interna, Azienda Sanitaria Universitaria Giuliano Isontina, Gorizia; ²SC Ematologia, Azienda Sanitaria Universitaria Giuliano Isontina, Trieste, Italy

Società Italiana di Reumatologia

DOI https://doi.org/10.4081/reumatismo.2025.2181
- 341 abstract views
PO:22:029 | Impact of mepolizumab on idiopathic hypereosinophilic syndromes: analysis of a monocentric retrospective cohort

Jacopo Mora¹, Francesca Regola¹, Paola Toniati², Ilaria Cavazzana¹, Franco Franceschini¹. | ¹ASST Spedali Civili e Università degli Studi di Brescia, Brescia, Italy; ²ASST Spedali Civili di Brescia, Brescia, Italy.

Società Italiana di Reumatologia

DOI https://doi.org/10.4081/reumatismo.2025.2053
- 281 abstract views
PO:22:032 | Beyond the joints: a rare case of subcorneal pustular dermatosis in Rheumatoid Arthritis

Sara Casella^1|2, Carlo Smirne^1|2, Roberta Zaira Pedrazzoli³, Mattia Perazzi^1|3, Edoardo Cammarata⁴, Francesca Zottarelli⁴, Paola Savoia⁵, Renzo Boldorini⁶, Mario Pirisi^1|2, Pier Paolo Sainaghi^1|3 | ¹Dipartimento di Medicina Traslazionale, Università del Piemonte Orientale Novara, Italy; ²Unità di Medicina Interna, Azienda Ospedaliera Maggiore della Carità Novara, Italy; ³Unità di Medicina Interna e Reumatologia, Azienda Ospedaliera Maggiore della Carità Novara, Italy; ⁴Unità di Dermatologia, Azienda Ospedaliera Maggiore della Carità Novara, Italy; ⁵Dipartimento di Scienze della salute, Università del Piemonte Orientale Novara, Italy; ⁶Unità di Anatomia Patologica, Azienda Ospedaliera Maggiore della Carità Novara, Italy

Società Italiana di Reumatologia

DOI https://doi.org/10.4081/reumatismo.2025.2345
- 243 abstract views
PO:22:033 | Unraveling VEXAS syndrome: when skin manifestations and monoclonal gammopathy precede hematological myeloid alterations

Laura Di Centa¹, Simone Longhino¹, Valeria Manfrè¹, Stefania Sacco¹, Luca Quartuccio¹ | ¹ASST Papa Giovanni XXIII, Bergamo, Italy

Società Italiana di Reumatologia

DOI https://doi.org/10.4081/reumatismo.2025.2182
- 333 abstract views
PO:22:038 | Recurrent Pneumonias and Persistent Inflammation in VEXAS Syndrome: The Role of BAL in Differential Diagnosis

Francesco Ghellere¹, Bernardo D'Onofrio¹, Maria Chiara Ditto¹, Salvatore Panaro¹, Francesca Piccione^1|2, Giacomo Tanti¹, Enrico Fusaro¹, Simone Parisi¹ | ¹SC Reumatologia, Città della Salute e della Scienza Torino, Italy; ²Fondazione Ricerca Molinette Torino, Italy

Società Italiana di Reumatologia

DOI https://doi.org/10.4081/reumatismo.2025.2346
- 151 abstract views
PO:22:039 | A rare form of interstitial lung disease: granulomatous and lymphocytic interstitial lung disease

Francesca Cozzini^1|2, Francesco Falco¹, Alberto Cavazza¹, Lucia Spaggiari³, Chiara Marvisi¹, Francesca Petrillo^1|2, Caterina Ricordi^1|2, Francesco Muratore^1|2, Fabio Brandolino¹, Ilaria Chiapparoli¹, Carlo Salvarani^1|2, Andreina Manfredi^1|2 | ¹IRCCS Policlinico San Matteo, UO di Reumatologia, Pavia; ²Università degli studi di Modena e Reggio Emilia, Modena, Italy

Società Italiana di Reumatologia

DOI https://doi.org/10.4081/reumatismo.2025.2183
- 291 abstract views
PO:23:044 | Understanding fatigue through patients' eyes: development of a novel questionnaire capturing the complexity of real-life fatigue in Sjögren's disease

Flavia Riccio¹, Mariachiara Visconti¹, Corrado Parlati¹, Nicola Della Rossa¹, Sabrina Marrone¹, Enrico Tirri², Francesco Ciccia¹, Saviana Gandolfo². | ¹UOC di Reumatologia, Università degli Studi della Campania Luigi Vanvitelli, Napoli, Italy; ²UO di Reumatologia, Ospedale del Mare, Napoli, Italy.

Società Italiana di Reumatologia

DOI https://doi.org/10.4081/reumatismo.2025.2054
- 311 abstract views
PO:23:046 | Histopathological comparison between minor salivary gland biopsies from pediatric and adult patients with Sjögren’s disease: evidence of a more severe inflammatory profile in early-onset cases

Flavia Riccio¹, Mattia Neri², Martina Mellone¹, Immacolata Cozzolino³, Jacopo Ferro⁴, Valerio Gaetano Vellone⁴, Ciro Emiliano Boschetti⁵, Giuseppe Colella⁵, Nicola Laffi⁶, Pietro Buono⁷, Enrico Tirri⁸, Renato Franco³, Marco Gattorno², Francesco Ciccia¹, Clara Malattia², Saviana Gandolfo⁸ | ¹UOC di Reumatologia, Università degli Studi della Campania Luigi Vanvitelli, Napoli; ²UOC di Reumatologia e Malattie Autoinfiammatorie, Istituto Giannina Gaslini, Genova; ³UO di Anatomia Patologica, Università degli Studi della Campania Luigi Vanvitelli, Napoli; ⁴UOC di Anatomia Patologica, Istituto Giannina Gaslini Genova; ⁵UOC di Chirurgia Maxillo-facciale, Università degli Studi della Campania Luigi Vanvitelli, Napoli; ⁶UO di Odontoiatria, Istituto Giannina Gaslini, Genova; ⁷UOD Attività consultoriali e assistenza materno-infantile, Direttorato Generale per la Salute, Regione Campania, Napoli; ⁸UO di Reumatologia, Ospedale del Mare, Napoli, Italy

Società Italiana di Reumatologia

DOI https://doi.org/10.4081/reumatismo.2025.2184
- 315 abstract views
PO:23:048 | Clinical and serological differences of an Italian Sjögren’s disease cohort according to three geographic macro-area localization

Maria Letizia Currò¹, Roberto Dal Pozzolo², Giacomo Cafaro², Valeria Manfrè³, Gaetano La Rocca⁴, Alessia Alunno⁵, Francesco Carubbi⁵, Nicoletta Del Papa⁶, Viktoriya Pavlych⁷, Angelica Gattamelata⁸, Letizia Pia Di Corcia⁹, Pamela Bernardini¹⁰, Luca Quartuccio³, Chiara Baldini⁴, Paola Cipriani⁷, Roberta Priori⁸, Onorina Berardicurti⁹, Serena Guiducci¹⁰, Fabiola Atzeni¹, Elena Bartoloni² | ¹Unità di Reumatologia. Università di Messina, Italy; ²SC Reumatologia. Università di Perugia, Italy; ³Unità di Reumatologia. Università di Udine, Italy; ⁴Unità di Reumatologia. Università di Pisa, Italy; ⁵Divisione di Medicina Interna e Nefrologia. Università di L'Aquila, Italy; ⁶Dipartimento di Reumatologia. Università di Milano, Italy; ⁷Unità di Reumatologia. Università di L'Aquila, Italy; ⁸UOC Reumatologia. Università Sapienza Roma, Italy; ⁹Unità di Reumatologia. Università Campus Biomedico Roma, Italy; ¹⁰Unità di Reumatologia. Università di Firenze, Italy

Società Italiana di Reumatologia

DOI https://doi.org/10.4081/reumatismo.2025.2347
- 128 abstract views
PO:23:051 | Quantitative high-resolution computed tomography analysis in Sjögren’s disease-associated interstitial lung disease: CALIPER-derived imaging biomarkers for prognostic assessment

Gaetano La Rocca¹, Francesco Ferro¹, Vincenzo Uggenti², Beatrice Dei¹, Giovanni Fulvio¹, Michele Moretti¹, Chiara Romei², Marta Mosca¹, Chiara Baldini¹. | ¹University of Pisa, Rheumatology Unit, Clinical and Experimental Medicine Department, Pisa, Italy; ²Department of Diagnostic Imaging, Pisa University Hospital, Pisa, Italy.

Società Italiana di Reumatologia

DOI https://doi.org/10.4081/reumatismo.2025.2055
- 317 abstract views
PO:23:052 | Muscular and myocardial involvement in antisynthetase syndrome: a retrospective real-life study

Giulia Buonsante^1|2|3, Giacomo De Luca^1|2|3, Veronica Batani^1|2, Daniele Scaramuzzi^1|2|3, Lorenzo Dagna^1|2|3, Marco Matucci-Cerinic^1|2|3, Corrado Campochiaro^1|2|3. | ¹Unit of Immunology, Rheumatology, Allergy and Rare Diseases UNIRAR, IRCCS San Raffaele Hospital, Milano, Italy; ²Inflammation, Fibrosis and aging Initiative INFLAGE, IRCCS San Raffaele Hospital, Milano, Italy; ³Vita-Salute San Raffaele University, Milan, Italy, Milano, Italy.

Società Italiana di Reumatologia

DOI https://doi.org/10.4081/reumatismo.2025.2056
- 319 abstract views
PO:23:055 | Overlap of systemic sclerosis and Sjögren’s disease: insights from an Italian case-control study

Stefano Stano¹, Fabio Cacciapaglia^1|2, Maria Morrone¹, Simone Perniola¹, Marco Capodiferro¹, Marco Fornaro¹, Laura Coladonato¹, Giuseppe Lopalco¹, Florenzo Iannone¹. | ¹Rheumatology Unit - Department of Precision and Regenerative Medicine, Jonian Area DiPReMeJ, University of Bari, Bari, Italy; ²Rheumatology Service, Internal Medicine Unit F. Miulli General Hospital, Department of Medicine and Surgery, LUM Casamassima Italy.

Società Italiana di Reumatologia

DOI https://doi.org/10.4081/reumatismo.2025.2057
- 515 abstract views
PO:24:056 | Major salivary gland ultrasonographic features of lymphoma and high lymphoproliferative risk lesions in Sjögren’s disease: a systematic review

Alessia Nano¹, Valeria Manfrè¹, Maria Teresa Rizzo¹, Garifallia Sakellariou², Alen Zabotti¹, Luca Quartuccio¹. | ¹Division of Rheumatology, Department of Medicine DMED, ASUFC, University of Udine, Udine, Italy; ²Department of Internal Medicine and Therapeutics, University of Pavia, Pavia, Italy.

Società Italiana di Reumatologia

DOI https://doi.org/10.4081/reumatismo.2025.2058
- 296 abstract views
PO:24:057 | Qualitative and quantitative analysis of nailfold videocapillaroscopy in patients with idiopathic inflammatory myopathies: focus on muscle histology

Jacopo Landro¹, Marius Cadar¹, Davide Mohammad Reza Beigi^1|2, Ilaria Bisconti¹, Francesca Romana Di Ciommo¹, Elena Platania¹, Martina Salerno¹, Beatrice De Girolamo¹, Annalisa Villa¹, Angelica Gattamelata¹, Simona Truglia¹, Cristiano Alessandri¹, Fabrizio Conti¹, Valeria Riccieri¹. | ¹Policlinico Umberto I, Roma, Italy; ²Clinica Reumatologica Madonna dello Scoglio, Cotronei, Italy.

Società Italiana di Reumatologia

DOI https://doi.org/10.4081/reumatismo.2025.2059
- 346 abstract views
PO:24:058 | Serum ferritin as a biomarker in idiopathic inflammatory myopathies with interstitial lung disease: baseline levels and longitudinal trends

Silvia Grazzini¹, Edoardo Conticini¹, Marco Fornaro², Chiara Rizzo³, Federica Camarda³, Paolo Cameli⁴, Miriana D'Alessandro⁴, Lidia La Barbera³, Stefano Stano², Maria Rosa Pellico⁵, Latika Gupta⁶, Florenzo Iannone², Giuliana Guggino³, Elena Bargagli⁴, Nicoletta Del Papa⁵, Luca Cantarini¹, Bruno Frediani¹. | ¹Reumatologia, Dipartimento di Scienze Mediche, Chirugiche e Neuroscienze, Università di Siena, Siena, Italy; ²Reumatologia, Dipartimento di Emergenza e Trapianto d'Organo, Università di Bari, Bari, Italy; ³Reumatologia, Promozione della Salute, Materno-Infantile, di Medicina Interna e Specialistica, Università di Palermo, Palermo, Italy; ⁴Pneumologia, Dipartimento di Scienze Mediche, Chirugiche e Neuroscienze, Università di Siena, Siena, Italy; ⁵Reumatologia Clinica e Scienze Mediche, ASST Gaetano Pini CTO, Milano, Italy; ⁶University of Manchester, Manchester, United Kingdom.

Società Italiana di Reumatologia

DOI https://doi.org/10.4081/reumatismo.2025.2060
- 314 abstract views
PO:24:059 | Sjögren's disease-associated Fibromyalgia: pitfalls in disease assessment using ESSDAI and ESSPRI

Lucia Cristiana Colaprico¹, Stefano Stano¹, Daniele Domanico¹, Maria Iacovantuono², Eduardo Urgesi³, Fabio Cacciapaglia^1|4, Maria Giannotta¹, Paola Conigliaro², Vincenzo Venerito¹, Maria Sole Chimenti², Giuseppe Lopalco¹, Florenzo Iannone¹ | ¹Rheumatology Unit - Department of Precision and Regenerative Medicine, Jonian Area DiPReMeJ, University of Bari, Bari, Italy; ²University of Rome Tor Vergata, Rheumatology, Allergology and Clinical Immunology, Department of Systems Medicine, Roma, Italy; ³University Cardiologic Unit - Interdisciplinary Department of Medicine - Policlinico University Hospital, University Bari, Italy; ⁴Rheumatology Service, Internal Medicine Unit F. Miulli General Hospital, Department of Medicine and Surgery, LUM Casamassima, Italy

Società Italiana di Reumatologia

DOI https://doi.org/10.4081/reumatismo.2025.2348
- 174 abstract views
PO:24:060 | Evaluation of a Large Language Model Performance in Rating Cutaneous Manifestations of Dermatomyositis: A Comparison with Expert Assessors

Gianmarco Roselli¹, Marco Fornaro¹, Swapnasha Panigrahi², Sara Sabbagh³, Florenzo Iannone¹, Vincenzo Venerito¹, Latika Gupta⁴ | ¹Università degli Studi di Bari, Unità di Reumatologia, DiMePRe-J Bari, Italy; ²University of Birmingham Birmingham, United Kingdom; ³Medical College of Wisconsin, Unit of Rheumatology, Department of Paediatrics Milwaukee, USA; ⁴University of Manchester, Manchester Academic Health Centre, Division of muscoloskeletal and deramatological sciences Manchester, United Kingdom

Società Italiana di Reumatologia

DOI https://doi.org/10.4081/reumatismo.2025.2349
- 121 abstract views
PO:24:061 | Allodynia is highly prevalent in patients with Sjögren’s disease and correlates with immunobiological disease markers: preliminary results from the sjnapse project

Flavia Riccio¹, Maria Chiara Visconti¹, Corrado Parlati¹, Nicola Della Rossa¹, Sabrina Marrone¹, Enrico Tirri², Francesco Ciccia¹, Saviana Gandolfo² | ¹UOC di Reumatologia, Università degli Studi della Campania Luigi Vanvitelli, Napoli; ²UO di Reumatologia, Ospedale del Mare, Napoli, Italy

Società Italiana di Reumatologia

DOI https://doi.org/10.4081/reumatismo.2025.2185
- 344 abstract views
PO:24:062 | Transcriptomic profile of salivary glands in patients with primary Sjögren’s syndrome and interstitial lung disease: implications for pathogenesis and risk stratification

Elisa Pignatti¹, Monia Maccaferri¹, Alessandra Bisagni², Alberto Cavazza², Marco Sebastiani^3|4, Luca Keller², Luca Magnani⁵, Claudio Galluzzo², Tommaso Fasano⁶, Lucia Nota⁶, Giulia Canu⁶, Andreina Manfredi^1|2, Carlo Salvarani^1|2 | ¹Dipartimento Chimomo, Università di Modena e Reggio Emilia Modena; ²Struttura Complessa di Reumatologia, Azienda Unità Sanitaria Locale di Reggio Emilia-IRCCS; ³Dipartimento di Medicina e Chirurgia, Università degli Studi di Parma; ⁴Divisione di Reumatologia, AUSL di Piacenza; ⁵UOC Medicina Interna ind. reumatologico, AUSL di Bologna, Ospedale Maggiore, Bologna; ⁶Dipartimento Interaziendale ad Attività Integrata Medicina di Laboratorio ed Anatomia Patologica AUSL di Modena, Italy

Società Italiana di Reumatologia

DOI https://doi.org/10.4081/reumatismo.2025.2186
- 314 abstract views
PO:24:063 | Interstitial lung disease in idiopathic inflammatory myopathy patients: efficacy and safety of nintedanib

Giulia Buonsante^1|2|3, Giacomo De Luca^1|2|3, Veronica Batani^1|2, Lorenzo Dagna^1|2|3, Marco Matucci-Cerinic^1|2|3, Corrado Campochiaro^1|2|3 | ¹Unit of Immunology, Rheumatology, Allergy and Rare Diseases UNIRAR, IRCCS San Raffaele Hospital Milano, Italy; ²Inflammation, Fibrosis and aging Initiative INFLAGE, IRCCS San Raffaele Hospital Milano, Italy; ³Vita-Salute San Raffaele University, Milano, Italy

Società Italiana di Reumatologia

DOI https://doi.org/10.4081/reumatismo.2025.2350
- 235 abstract views
PO:24:064 | IPF vs CTD-ILD: Survival and Lung Function from an Italian Real-World Cohort

Marco Fornaro¹, Donato Lacedonia², Lorenzo Cavagna³, Paolo Airò⁴, Marco Sebastiani⁵, Gianluca Sambataro⁶, Fabio Cacciapaglia⁷, Angelica Napoletano¹, Cosimo De Pace², Pasquale Tondo², Giulia Scioscia², Eleonora Pedretti⁴, Maria Grazia Lazzaroni⁴, Carlo Vancheri⁸, Andreina Manfredi⁹, Lorenzo Binchessi³, Rocco Capece³, Michele De Ceglie¹⁰, Massimo Giotta¹¹, Florenzo Iannone¹ | ¹Unit of Rheumatology, Department of Precision and Regenerative Medicine - Area Jonica DiMePRe-J, University of Bari, Bari, Italy; ²Department of Medical and Surgical Sciences, University of Foggia Foggia, Italy; ³Department of Internal Medicine and Therapeutics, University of Pavia, Division of Rheumatology, Fondazione IRCCS, Pavia, Italy; ⁴Rheumatology and Clinical Immunology Unit, Department of Clinical and Experimental Sciences, ASST Spedali Civili Brescia, Italy; ⁵Rheumatology Unit, AUSL Piacenza, Department of Medicine and Surgery, University of Parma, Parma, Italy; ⁶Department of Medicine and Surgery, University of Enna Kore, Enna, Italy; ⁷Rheumatology Service, F. Miulli Hospital and Department of Medicine and Surgery, LUM University, Casamassima, Italy; ⁸Department of Clinical and Experimental Medicine, Regional Referral Center for Rare Lung Diseases, Catania, Italy; ⁹Rheumatology Unit, IRCCS Santa Maria Nuova Reggio Emilia, University of Modena, Modena, Italy; ¹⁰DIM, Interdisciplinary Department of Medicine, Section of Diagnostic Imaging, University of Bari, Bari, Italy; ¹¹Health Prevention Department, Local Health Authority of Brindisi, Brindisi, Italy

Società Italiana di Reumatologia

DOI https://doi.org/10.4081/reumatismo.2025.2351
- 257 abstract views
PO:24:065 | Nailfold capillaroscopic in primary Sjögren's syndrome, clinical and serological correlations; a preliminary report from a reference center

Caterina Vacchi¹, Filippo Santoro¹, Maria Grazia Malandra¹, Giulia Cassone¹, Alessandra Carobbio², Martina Orlandi¹, Dilia Giuggioli¹ | ¹Reumatologia Modena, Italy; ²Statistica Medica Modena, Italy

Società Italiana di Reumatologia

DOI https://doi.org/10.4081/reumatismo.2025.2352
- 120 abstract views
PO:24:066 | Antibody profile in myositis and early risk of interstitial lung disease: clinical and laboratory correlations in patients with suspected rheumatologic disease

Lindsay Brooke Boling¹, Gaia Deleonardi², Alarico Ariani³, Tania Silvestri², Ana Gabriela Grondona², Marica Trevisani³, Rita Mulè³, Enrica Vandelli³, Gentiana Vukatana³, Elisa Rossi³, Olga Addimanda³, Francesca Bergossi³, Angela Buffa³, Giovanni B. Canestrari³, Francesco Cianci³, Daniela Chiarini³, Laura Gigante³, Nicolò Girolimetto³, Daniele Lini³, Luca Magnani³, Mirco Magnani³, Erika Meleddu³, Francesca Pignataro³, Sofia Testoni³, Massimo Reta³ | ¹Scuola di Allergologia ed Immunologia Clinica-Università di Bologna; ²LUM Laboratorio Unico Metropolitano - Immunologia Clinica, Ospedale Maggiore, Bologna; ³UO Medicina Interna ad indirizzo reumatologico SC interaziendale - IRCCS AOU, AUSL Bologna, Italy

Società Italiana di Reumatologia

DOI https://doi.org/10.4081/reumatismo.2025.2187
- 343 abstract views
PO:24:068 | Case Report: ‘Spontaneous Pneumomediastinum in a Patient with MDA5-Positive Dermatomyositis and Severe Pulmonary Fibrosis’

Carlotta Braga¹, Margherita Rizzo¹, Marta Raschellà¹, Beatrice Maranini¹, Gioacchino Schifino², Aldo Carnevale³, Marcello Govoni¹, Andrea Lo Monaco¹ | ¹Rheumatology Unit, Department of Medical Sciences, University of Ferrara and Azienda Ospedaliero-Universitaria S. Anna Ferrara, Italy; ²Respiratory Medicine Unit, Department of Cardio-Thoracic-Vascular Pathologies, Arcispedale Sant'Anna, Ferrara, Italy; ³Radiology Unit, Department of Translational Medicine, University of Ferrara, Italy

Società Italiana di Reumatologia

DOI https://doi.org/10.4081/reumatismo.2025.2353
- 191 abstract views
PO:24:070 | Preliminary descriptive data from a single-centre cohort of patients with idiopathic inflammatory myopathy: focus on paraneoplastic and non-paraneoplastic patients

Silvia Ebe Lucia Della Pina¹, Paola Bizioli¹, Samantha Mazza², Caproli Alessia¹, Cesare Tomasi¹, Ilaria Cavazzana¹, Franco Franceschini¹. | ¹S.C.O. Reumatologia ed Immunologia Clinica, ASST Spedali Civili di Brescia, Università degli Studi di Brescia, Brescia, Italy; ²Università degli Studi di Brescia, Brescia, Italy.

Società Italiana di Reumatologia

DOI https://doi.org/10.4081/reumatismo.2025.2061
- 267 abstract views
PO:25:071 | Gender differences in Sjögren’s disease: clinical activity, illness perception, and emotional impact

Ilenia Fischetti¹, Martina Salerno¹, Linda Mastromanno¹, Angelica Gattamelata¹, Martina Villa¹, Ludovica Manisera¹, Emanuele Grilli¹, Luca Quartuccio², Valeria Manfrè², Francesco Carubbi³, Evy Di Ruscio³, Fabrizio Conti¹, Roberta Priori^1|4 | ¹UOC di Reumatologia, Dipartimento SCIAC, Sapienza Università di Roma; ²Dipartimento di Medicina, Clinica di Reumatologia, Università degli Studi di Udine; ³UOC Medicina Interna e Nefrologia, Dipartimento MeSVA, Università degli Studi di L'Aquila; ⁴UniCamillus, San Camillo Università Internazionale di Scienze della Salute di Roma, Italy

Società Italiana di Reumatologia

DOI https://doi.org/10.4081/reumatismo.2025.2188
- 312 abstract views
PO:25:073 | Pulmonary involvement and progressive interstitial lung disease in anti-synthetase syndrome: a single-center retrospective study

Daniele Scaramuzzi^1|3, Giacomo De Luca^1|3, Veronica Batani¹, Giulia Buonsante^1|3, Lorenzo Dagna^1|3, Marco Matucci-Cerinic^1|2|3, Corrado Campochiaro^1|2|3 | ¹Unità di Immunologia, Reumatologia, Allergologia e Malattie Rare, IRCCS Ospedale San Raffaele, Milano; ²Inflammation, Fibrosis and Ageing Initiative INFLAGE, IRCCS San Raffaele Hospital, Milano; ³Università Vita-Salute San Raffaele, Milano, Italy

Società Italiana di Reumatologia

DOI https://doi.org/10.4081/reumatismo.2025.2189
- 313 abstract views
PO:25:074 | Capillaroscopic assessment in interstitial lung disease: a comparative study between connective tissue disease-associated interstitial lung disease, interstitial pneumonia with autoimmune features, and idiopathic pulmonary fibrosis

Daniele Vito Andrea Sabella¹, Marco Fornaro¹, Laura Coladonato¹, Marlea Lavista¹, Veronica Spedicato¹, Giuseppe Lopalco¹, Florenzo Iannone¹. | ¹University of Bari, Rheumatology Unit Department of Precision and Regenerative Medicine - Jonica Area DiMePRe-J, Bari, Italy.

Società Italiana di Reumatologia

DOI https://doi.org/10.4081/reumatismo.2025.2062
- 294 abstract views
PO:25:075 | Cancer occurence in patients with idiopathic inflammatory myopathies: new insights from the analysis of a monocentric cohort

Michele Diomedi¹, Federico Fattorini¹, Simone Barsotti², Chiara Cardelli^1|3, Elenia Laurino⁴, Alessandra Tripoli⁴, Linda Carli⁴, Marta Mosca^1|4. | ¹Rheumatology Unit, Department of Clinical and Experimental Medicine, University of Pisa, Pisa, Italy; ²Rheumatology, Versilia Hospital, Viareggio, Italy; ³Department of Medical Biotechnologies, University of Siena, Siena, Italy; ⁴Rheumatology Unit, AOUP, Pisa, Italy.

Società Italiana di Reumatologia

DOI https://doi.org/10.4081/reumatismo.2025.2063
- 309 abstract views
PO:25:079 | Anifrolumab in refractory dermatomyositis: a case report

Chiara Calabrese¹, Corrado Campochiaro^1|2, Giacomo De Luca ^1|2, Veronica Batani¹, Marco Matucci-Cerinic^1|2, Lorenzo Dagna ^1|2 | ¹Dipartimento di Reumatologia e Scienze Mediche, ASST Centro Specialistico Ortopedico Traumatologico Gaetano Pini-CTO Milano; ²Università degli Studi di Milano, Dipartimento di Fisiopatologia Medico-Chirurgica e Trapianti, Milano, Italy

Società Italiana di Reumatologia

DOI https://doi.org/10.4081/reumatismo.2025.2190
- 357 abstract views
PO:25:081 | Atypical onset of anti-SAE-1 positive dermatomyositis: paraneoplastic flame hemorrhages in urothelial carcinoma

Valentina Morandi¹, Alessandro Biglia², Francesco Maggiore¹, Sofia Chiricolo¹, Silvia Sammorì¹, Maria Cristina Sacchi^3|4, Edoardo Cammarata⁵, Maria Rosa Pellico⁶, Luigi Mario Castello^2|3|7. | ¹Dipartimento di Medicina Interna, SSD Reumatologia, AOUAL Santi Antonio e Biagio e Cesare Arrigo, Alessandria, Italy; ²Dipartimento di Medicina Interna, AOUAL Santi Antonio e Biagio e Cesare Arrigo, Alessandria, Italy; ³Dipartimento di laboratorio di tecnologia, ricerca e innovazione DAIRI, AOUAL Santi Antonio e Biagio e Cesare Arrigo, Alessandria, Italy; ⁴AOUAL Santi Antonio e Biagio e Cesare Arrigo, Laboratorio Analisi, Alessandria, Italy; ⁵AOUAL Santi Antonio e Biagio e Cesare Arrigo, Dipartimento di Medicina Interna, SSD Dermatologia, Alessandria, Italy; ⁶ASST Gaetano Pini, divisione di Reumatologia Clinica, Milano, Italy; ⁷Università del Piemonte orientale, dipartimento di Medicina Traslazione, Novara, Italy.

Società Italiana di Reumatologia

DOI https://doi.org/10.4081/reumatismo.2025.2064
- 470 abstract views
PO:25:082 | Progressive interstitial lung disease secondary to Sjögren's disease in a patient with inclusion body myositis complicated by dysphagia: a multidisciplinary approach and therapeutic challenges

Emanule Cocchiara¹, Francesco Falco¹, Lucia Spaggiari³, Francesca Cozzini^1|2, Lucia Dardani¹, Gianluigi Bajocchi¹, Andreina Manfredi^1|2, Carlo Salvarani^1|2 | ¹Dipartimento di Medicina, Clinica Reumatologica, Udine; ²Università degli studi di Modena e Reggio Emilia, Modena; ³AUSL area NORD, Guastalla-Montecchio, Italy

Società Italiana di Reumatologia

DOI https://doi.org/10.4081/reumatismo.2025.2191
- 329 abstract views
PO:25:083 | Overlap between Sjögren’s syndrome and lichen sclerosus: beyond coincidence?

Emanuele Giovanni Grilli¹, Ludovica Manisera¹, Ilenia Fischetti¹, Linda Mastromanno¹, Martina Villa¹, Angelica Gattamelata¹, Fabrizio Conti¹, Roberta Priori^1|2, Serena Colafrancesco^3|4 | ¹Dipartimento di Medicina e Chirurgia, Università Milano-Bicocca; ²U.O. Reumatologia, IRCCS Fondazione San Gerardo dei Tintori, Monza; ³U.O. Pneumologia, IRCCS Fondazione San Gerardo dei Tintori, Monza; ⁴Rheumatology and Clinical Immunology, Istituto di Ricovero e Cura a Carattere Scientifico, IRCCS Humanitas Research Hosp, Rozzano, Milano, Italy

Società Italiana di Reumatologia

DOI https://doi.org/10.4081/reumatismo.2025.2192
- 445 abstract views
PO:25:085 | Anti-MDA5 antibody syndrome, a life-threatening condition for rheumatologist and pulmonologist A case series

Francesca Cozzini^1|2, Cecilia Burattini¹, Elena Bravi¹, Chiara Nani¹, Eugenio Arrigoni¹, Fabia Cavallotti¹, Ilaria Platè¹, Marco Sebastiani^1|3 | ¹Ospedale Guglielmo da Saliceto Piacenza, Italy; ²Università degli studi di Modena e Reggio Emilia, Italy; ³Università degli Studi di Parma, Italy

Società Italiana di Reumatologia

DOI https://doi.org/10.4081/reumatismo.2025.2354
- 194 abstract views
PO:26:087 | Rituximab versus glucocorticoids for IgG4-related disease: a European retrospective multi-center study of 167 patients

Marco Lanzillotta¹, Jens Vikse², Elisabetta Goni³, Jasmin Mahajne¹, Veronica Batani¹, Lorenzo Dagna¹, Emanuel Della-Torre¹ | ¹Unit of Immunology, Rheumatology, Allergy, and Rare Disease, IRCCS Ospedale san Raffaele Milano, Italy; ²Department of Rheumatology, Stavanger University Hospital, Stavanger, Norway; ³Department of Medicine II, University Hospital, Ludwig Maximilian University Munich, Munich Germany

Società Italiana di Reumatologia

DOI https://doi.org/10.4081/reumatismo.2025.2355
- 271 abstract views
PO:26:088 | Rheumatologic immune-related adverse events from immune checkpoint inhibitors: a monocentric retrospective study

Giulio Fraticelli^1|2, Nicola Farina^1|2, Alessandro Tomelleri^1|2, Marco Matucci Cerinic^1|2, Corrado Campochiaro^1|2, Lorenzo Dagna^1|2. | ¹Unit of Immunology, Rheumatology, Allergy and Rare Diseases UNIRAR, IRCCS San Raffaele Hospital, Milano, Italy; ²Inflammation, Fibrosis and Ageing Initiative INFLAGE, IRCCS San Raffaele Hospital, Milano, Italy.

Società Italiana di Reumatologia

DOI https://doi.org/10.4081/reumatismo.2025.2065
- 327 abstract views
PO:26:092 | Early antiproteinuric effect of voclosporine in patients with lupus nephritis in real life setting: preliminary results from the VoRLiSS (Voclosporine in Real Life Setting Study)

Aurora Di Gregorio¹, Marta Calatroni², Marco Allinovi³, Alessandra Bortoluzzi⁴, Giorgio Buscetta⁵, Rossella De Angelis⁶, Ginevra De Marchi⁷, Giacomo Emmi⁸, Pasquale Esposito⁹, Paride Fenaroli¹⁰, Micaela Fredi¹¹, Giovanni Orsolini¹², Giulia Pazzola¹³, Domenico Santoro¹⁴, Andrea Doria¹, Gabriella Moroni², Luca Iaccarino¹ | ¹Azienda Ospedaliera Universitaria Padova, Italy; ²Ospedale IRCCS Humanitas Milano, Italy; ³Azienda Ospedaliero Universitaria Careggi Firenze, Italy; ⁴Azienda Ospedaliero Universitaria di Ferrara, Italy; ⁵Policlinico Universitario Paolo Giaccone Palermo, Italy; ⁶Università Politecnica delle Marche Ancona, Italy; ⁷Università di Udine, Italy; ⁸Università di Trieste, Italy; ⁹Università di Genova, Italy; ¹⁰Unità di Nefrologia AUSL IRCCS di Reggio Emilia, Italy; ¹¹Università di Brescia, Italy; ¹²Università di Verona Verona, Italy; ¹³Università di Reggio Emilia, Italy; ¹⁴Azienda Ospedaliera Universitaria G. Martino di Messina, Italy

Società Italiana di Reumatologia

DOI https://doi.org/10.4081/reumatismo.2025.2356
- 190 abstract views
PO:26:095 | Educational online webinars of European Reference Network on rare and complex connective tissue and musculoskeletal diseases for patients, caregivers and healthcare professionals: six years' experience

Emanuele Gotelli^1|2, Rosanna Campitiello^1|3, Eric Hachulla^4|5|6, Vanessa Smith^7|8|9, Joao Eurico Fonseca^10|11, Tadej Avcin^12|13, Gabriele Simonini^14|15, Silvia Aguilera¹⁶, Lisa Matthews¹⁷, Charissa Frank¹⁸, Wiebke Lautré¹⁹, Monica Testoni²⁰, Diana Marinello²⁰, Rosaria Talarico²⁰, Marta Mosca²⁰, Maurizio Cutolo^1|2. | ¹Department of Internal Medicine and Specialties, University of Genova, Genova, Italy; ²IRCCS Ospedale Policlinico San Martino, Genova, Italy; ³Department of Experimental Medicine DIMES, University of Genova, Genova, Italy; ⁴Institute for Translational Research in Inflammation INFINITE, Université de Lille, Lille, France; ⁵INSERM, Lille, France; ⁶Centre de référence des maladies autoimmunes systemiques rares du Nord et Nord-Ouest de France CeRAINO, Lille, France; ⁷Department of Internal Medicine, University of Ghent, Ghent University Hospital, Ghent, Belgium; ⁸Department of Rheumatology, University of Ghent, Ghent University Hospital, Ghent, Belgium; ⁹Unit for Molecular Immunology and Inflammation, Flemish Institute for Biotechnology, Inflammation Research Center, Ghent, Belgium; ¹⁰Centro Hospitalar Universitário Lisboa Norte EPE, Serviço de Reumatologia e Doenças Ósseas Metabólicas Lisboa Portugal; ¹¹Universidade de Lisboa, Unidade de Investigação em Reumatologia, Instituto de Medicina Molecular João Lobo Antunes Lisboa Portugal; ¹²University Children Hospital, University Medical Center Ljubljana, Ljubljana, Slovenia; ¹³University of Ljubljana, Department of Paediatrics, Ljubljana, Slovenia; ¹⁴University of Florence, NEUROFARBA Department, Firenze, Italy; ¹⁵Meyer Children Hospital IRCCS, Rheumatology Unit, Firenze, Italy; ¹⁶Spanish Association for Antiphospholipid Syndrome, Elche, Spain; ¹⁷Relapsing Polychondritis Awareness and Support, Worcester, United Kingdom; ¹⁸Flemish Association for Hereditary Connective Tissue Disorders, Koersel, Belgium; ¹⁹CHU Bordeaux Pellegrin, Centre de Références Maladies Auto-Immunes Systémiques Rares, Bordeaux, France; ²⁰Azienda Ospedaliero Universitaria Pisana, Pisa, Italy.

Società Italiana di Reumatologia

DOI https://doi.org/10.4081/reumatismo.2025.2066
- 317 abstract views
PO:26:096 | From free text to diagnosis: a Natural Language Processing approach for identifying rheumatoid and psoriatic arthritis in the Emergency Department

Antonio Tonutti^1|2, Pierandrea Morandini³, Cosimo Faeti³, Nicoletta Luciano^1|2, Saverio D'Amico³, Antonio Voza^1|4, Victor Savevski³, Carlo Selmi^1|2 | ¹Department of Biomedical Sciences, Humanitas University Pieve Emanuele, Milan, Italy; ²Rheumatology and Clinical Immunology, IRCCS Humanitas Research Hospital Rozzano, Milan, Italy; ³Artificial Intelligence Unit, IRCCS Humanitas Research Hospital Rozzano, Milan, Italy; ⁴Emergency Department, IRCCS Humanitas Research Hospital Rozzano, Milan, Italy

Società Italiana di Reumatologia

DOI https://doi.org/10.4081/reumatismo.2025.2357
- 219 abstract views
PO:26:097 | Ultrasound evaluation of temporomandibular disorders: comparative analysis between inflammatory and degenerative patterns in patients with and without rheumatological pathologies

Beatrice Maranini¹, Stefano Mandrioli², Fabio Fabbian³, Tommaso Bianchi¹, Manlio Galiè², Marcello Govoni¹ | ¹UO di Reumatologia, Dipartimento di Scienze Mediche, Università di Ferrara; ²UO di Chirurgia Maxillo-Facciale, Dipartimento Testa-Collo, Università di Ferrara; ³Dipartimento di Scienze Mediche, Università di Ferrara, Italy

Società Italiana di Reumatologia

DOI https://doi.org/10.4081/reumatismo.2025.2193
- 312 abstract views
PO:27:105 | Sleep disturbances in patients with polymyalgia rheumatica: correlations with disease activity, fatigue, and glucocorticoid dosage

Ilaria Franch¹, Lorenzo Di Sanzo¹, Chiara Castellani², Giulia Bevignani¹, Lucia Colella¹, Veronica Alò¹, Fabrizio Conti¹, Rossana Scrivo¹ | ¹Università La Sapienza, Roma; ²Ospedale San Camillo De Lellis, Rieti, Italy

Società Italiana di Reumatologia

DOI https://doi.org/10.4081/reumatismo.2025.2194
- 553 abstract views
PO:27:106 | Role of histology in interstitial lung involvement of rheumatic diseases in real life scenario

Francesca Cozzini^1|2, Francesco Falco¹, Lucia Spaggiari^1|3, Alberto Cavazza¹, Adele Del Giudice^1|2, Lucia Dardani¹, Fabio Brandolino¹, Emanuele Cocchiara¹, Ilaria Chiapparoli¹, Luca Magnani⁴, Gianluigi Bajocchi¹, Carlo Salvarani^1|2, Andreina Manfredi^1|2 | ¹IRCCS Arcispedale Santa Maria Nuova Reggio Emilia, Italy; ²Università degli Studi di Modena e Reggio Emilia Modena, Italy; ³AUSL area NORD Montecchio-Guastalla, Italy; ⁴UOC di Medicina Interna ad Indirizzo Reumatologico, Azienda USL Bologna, Ospedale Maggiore Bologna, Italy

Società Italiana di Reumatologia

DOI https://doi.org/10.4081/reumatismo.2025.2358
- 219 abstract views
PO:27:108 | Delphi consensus on the shared management of patients with rheumatologic and oncologic diseases

Luigi De Marco¹, Augusta Ortolan², Antonio Carletto³, Fulvia Ceccarelli⁴, Lorenzo Dagna⁵, Ginevra De Marchi⁶, Ennio Giulio Favalli⁷, Alessandro Inno⁸, Giuseppe Lopalco⁹, Francesco Ciccia¹⁰, Ennio Lubrano¹¹, Luca Quartuccio¹², Immacolata Prevete¹³, Roberta Ramonda¹⁴, Nicola Silvestris¹⁵, Marcello Tiseo¹⁶, Michelina Turri¹, Maria Sole Chimenti¹ | ¹Reumatologia, allergologia e immunologia clinica, dipartimento di medicina dei sistemi, Università di Roma Tor Vergata; ²UOC Reumatologia e immunologia clinica, Fondazione Policlinico Universitario Agostino Gemelli IRCSS, Roma; ³Unità di Reumatologia, Dipartimento di medicina, AOUI università di Verona; ⁴Reumatologia, Dipartimento di Scienze Cliniche, Anestesiologiche Internistiche e Cardiovascolari, Sapienza Università di Roma; ⁵Unità di Immunologia, Reumatologia, Allergologia e malattie rare UnIRar, IRCSS San Raffaele, Milano; ⁶Unità di Reumatologia, Dipartimento di medicina, Azienda Sanitaria Universitaria Integrata, Università di Udine; ⁷Dipartimento di Reumatologia e scienze mediche, Istituto Gaetano Pini, Università di Milano; ⁸Oncologia Medica, IRCCS Ospedale Sacro Cuore Don Calabria, Negrar di Valpolicella (VR); ⁹UOC Reumatologia, Dipartimento di Medicina di Precisione e Rigenerativa e Area Ionica, Università di Bari "Aldo Moro"; ¹⁰Unità di Reumatologia, Dipartimento di Medicina di Precisione, Università della Campania L. Vanvitelli, Napoli; ¹¹Unità di Reumatologia, Università degli Studi del Molise, Campobasso; ¹²SOC Clinica Reumatologica - ASUFC, Dipartimento di Medicina, Università degli Studi di Udine; ¹³UOC Reumatologia Azienda Ospedaliera San Camillo-Forlanini, Roma; ¹⁴UOC di Reumatologia, Dipartimento di Medicina DIMED, Azienda Ospedale Università di Padova; ¹⁵UOC Oncologia Medica e Dipartimento Area Medica - IRCCS Istituto Tumori Giovanni Paolo II, Bari; ¹⁶UOC di Oncologia Medica, Azienda Ospedaliero-Universitaria di Parma, Italy

Società Italiana di Reumatologia

DOI https://doi.org/10.4081/reumatismo.2025.2195
- 334 abstract views
PO:27:112 | The impact of rurality in chronic inflammatory rheumatic diseases in the province of Udine (2014-2023): analysis of clinical outcomes and potential complications

Simone Longhino¹, Luigi Castrista², Yvonne Beorchia², Marco Driutti², Elena Treppo¹, Silvio Brusaferro³, Luca Quartuccio¹ | ¹Clinica di Reumatologia, Dipartimento di Medicina Specialistica; ²Istituto di Igiene ed Epidemiologia Valutativa; ³Accreditamento, Gestione del Rischio Clinico e Valutazione delle Performance Sanitarie, ASUFC, Udine, Italy

Società Italiana di Reumatologia

DOI https://doi.org/10.4081/reumatismo.2025.2196
- 354 abstract views
PO:28:116 | Glandular involvement in autoimmune diseases: a spectrum of differential diagnosis

Francesca Petrillo¹, Caterina Ricordi¹, Caterina Tomassini¹, Luca Cimino³, Giorgia Citriniti², Fabio Brandolino², Chiara Marvisi¹, Carlo Salvarani¹ | ¹S.C. Reumatologia; ²S.C. Reumatologia; ³S.S.D. Immunologia Oculare, Università di Modena e Reggio Emilia, Arcispedale Santa Maria Nuova, Reggio Emilia, Italy

Società Italiana di Reumatologia

DOI https://doi.org/10.4081/reumatismo.2025.2197
- 340 abstract views
PO:28:126 | Effectiveness of the new AMEL system in the treatment of simple painful shoulder syndrome

Antonietta Albanese¹, Emilio Battisti¹, Federico Filippi² | ¹Dipartimento SFTA, Università di Siena, Siena; ²Sanimed, Fisiomed, Vicenza, Italy

Società Italiana di Reumatologia

DOI https://doi.org/10.4081/reumatismo.2025.2198
- 441 abstract views
PO:28:127 | Efficacy of b/ts-DMARDS therapy on depressive and anxiety symptoms in patients with chronic inflammatory joint diseases: preliminary results of a prospective study

Nikita Pecani¹, Christian D'Elia¹, Francesca Bartoli¹, Sabrina Aliberti¹, Francesco Rotella², Arianna Ida Altomare², Francesco Vinci², Lorenzo Cortoni², Davide Benedetti³, Camilla Ferrari⁴, Gemma Lepri¹, Silvia Bellando Randone¹, Serena Guiducci¹ | ¹SOD Reumatologia, Dipartimento di Medicina Sperimentale e Clinica, Università degli Studi di Firenze; ²Unità di Psichiatria, Dipartimento di Scienze della Salute, Università degli Studi di Firenze; ³Dipartimento Salute Mentale, USL Umbria, Città di Castello (PG); ⁴Scuola di Scienze della Salute Umana - Università degli Studi di Firenze, Italy

Società Italiana di Reumatologia

DOI https://doi.org/10.4081/reumatismo.2025.2199
- 341 abstract views
PO:28:128 | Rheumatic fever: an atypical case

Giovanni Italiano¹, Melania Coscia¹, Arianna Monteforte¹ | ¹AORN S. Anna e S. Sebastiano Caserta, Italy

Società Italiana di Reumatologia

DOI https://doi.org/10.4081/reumatismo.2025.2359
- 185 abstract views
PO:29:131 | Early effect of auricular acupuncture on pain modulation in patients with fibromyalgia: findings from a real-life experience

Benedetta Bianchi¹, Edoardo Cipolletta¹, Sonia Farah¹, Fausto Salaffi¹, Marco Di Carlo¹ | ¹Clinica Reumatologica, Università Politecnica delle Marche, ospedale Carlo Urbani Jesi, Ancona, Italy

Società Italiana di Reumatologia

DOI https://doi.org/10.4081/reumatismo.2025.2360
- 193 abstract views
PO:29:132 | Autonomic Dysfunction in Fibromyalgia: A Cross-Sectional Study and Cluster Analysis of Clinical Phenotypes

Sergio Del Vescovo¹, Vincenzo Venerito¹, Maria Giannotta¹, Marco Fornaro¹, Greta Giulia Dipietrangelo¹, Andrea Cito¹, Maria Morrone¹, Giuseppe Lopalco¹, Florenzo Iannone¹ | ¹UOC Reumatologia, Policlinico di Bari, DiMePre-J Bari, Italy

Società Italiana di Reumatologia

DOI https://doi.org/10.4081/reumatismo.2025.2361
- 268 abstract views
PO:29:138 | Cetylated fatty acids and fibromyalgia: efficacy and tolerability in a prospective study

Anna Capogna¹, Marco Bardelli¹, Luca Cantarini¹, Bruno Frediani¹ | ¹UOC Reumatologia, Dipartimento di Scienze mediche, chirurgiche e neuroscienze, Università degli Studi di Siena, Italy

Società Italiana di Reumatologia

DOI https://doi.org/10.4081/reumatismo.2025.2200
- 344 abstract views
PO:29:139 | Modulation of autonomic dysfunction in fibromyalgia through auricular vagal nerve stimulation: preliminary results

Sonia Farah¹, Marco Di Carlo¹, Maria Giovanna Lommano¹, Benedetta Bianchi¹, Piercarlo Sarzi Puttini², Fausto Salaffi¹. | ¹Rheumatology Clinic, Università Politecnica delle Marche, Ospedale Carlo Urbani, Jesi, Italy; ²Rheumatology Unit, IRCCS Galeazzi-Sant Ambrogio Hospital, Milano State University School of Medicine, Milano, Italy.

Società Italiana di Reumatologia

DOI https://doi.org/10.4081/reumatismo.2025.2067
- 334 abstract views
PO:29:141 | Assessing psychosomatic diagnoses and psychological distress in patients with fibromyalgia. The clinical utility of a multidisciplinary approach

Sara Ceccatelli¹, Francesca Nacci², Ginevra Fiori², Gemma Lepri², Fiammetta Cosci³, Serena Guiducci² | ¹Dipartimento di Medicina Sperimentale e Clinica; ²Divisione di Reumatologia, Dipartimento di Medicina Sperimentale e Clinica; ³Dipartimento di Scienze della Salute, Università di Firenze, Italy

Società Italiana di Reumatologia

DOI https://doi.org/10.4081/reumatismo.2025.2201
- 287 abstract views
PO:29:144 | Refractory localized pain in fibromyalgia and the importance of differential diagnosis: two cases of Bertolotti’s syndrome and avascular necrosis successfully treated with targeted therapy

Andrea Lacarpia¹, Riccardo Terribili¹, Silvia Valentini¹, Marta Fabbroni¹, Stefano Barbagli¹, Stefano Gentileschi¹, Caterina Baldi¹, Luca Cantarini¹, Bruno Frediani¹ | ¹Azienda Ospedaliera Universitaria Senese, Università degli Studi di Siena, Italy

Società Italiana di Reumatologia

DOI https://doi.org/10.4081/reumatismo.2025.2202
- 324 abstract views
PO:29:145 | Fibromyalgia in idiopathic inflammatory myopathies: is it time for rheumatologists to investigate it?

Federico Fattorini¹, Michele Diomedi¹, Simone Barsotti², Elenia Laurino³, Chiara Cardelli^1|4, Alessandra Tripoli³, Linda Carli³, Marta Mosca^1|3. | ¹Rheumatology Unit, Department of Clinical and Experimental Medicine, University of Pisa, Pisa, Italy; ²Rheumatology, Versilia Hospital, Viareggio, Italy; ³Rheumatology Unit, AOUP, Pisa, Pisa, Italy; ⁴Department of Medical Biotechnologies, University of Siena, Siena, Italy.

Società Italiana di Reumatologia

DOI https://doi.org/10.4081/reumatismo.2025.2068
- 329 abstract views
PO:30:151 | Clinical characteristics and evolution of juvenile undifferentiated connective tissue diseases: results of a single-center study

Nicoletta D'Angelo^1|2, Stefania Costi³, Achille Marino³, Francesco Baldo³, Cecilia Beatrice Chighizola^1|3, Roberto Felice Caporali^1|2|3. | ¹Università degli Studi di Milano, Dipartimento di Scienze Cliniche e di Comunità, Milano, Italy; ²ASST G. Pini-CTO, UOC di Clinica Reumatologica, Milano, Italy; ³ASST G. Pini-CTO, UOC di Clinica Reumatologica Pediatrica, Milano, Italy

Società Italiana di Reumatologia

DOI https://doi.org/10.4081/reumatismo.2025.2069
- 490 abstract views
PO:30:152 | An altered immunometabolic profile characterizes B cells of patients with oligoarticular- and polyarticular- juvenile idiopathic arthritis

Emiliano Marasco¹, Angela Aquilani¹, Rebecca Nicolai¹, Maria Isabella Petrone¹, Giusyda Tarantino¹, Ivan Caiello¹, Sabina Barresi², Silvia Magni Manzoni¹, Fabrizio De Benedetti¹ | ¹Unità di Reumatologia, Ospedale Pediatrico Bambino Gesù Roma, Italy; ²UO di Anatomia Patologica, Ospedale Pediatrico Bambino Gesù Roma, Italy

Società Italiana di Reumatologia

DOI https://doi.org/10.4081/reumatismo.2025.2362
- 183 abstract views
PO:30:153 | Long-term outcomes of JIA-associated uveitis: a systematic review and meta-analysis

Laura Scagnellato¹, Giacomo Cozzi¹, Matteo Molfese¹, Mariagrazia Lorenzin¹, Jamie Alexander King¹, Gianluca Poncina¹, Stefano Rizzetto¹, Roberta Ramonda¹ | ¹UOC Reumatologia, Dipartimento di Medicina dei Sistemi DIMED, Ospedale Università di Padova, Italy

Società Italiana di Reumatologia

DOI https://doi.org/10.4081/reumatismo.2025.2363
- 230 abstract views
PO:30:155 | The role of nailfold videocapillaroscopy in the assessment of juvenile connective tissue diseases

Marco Binda¹, Beatrice Moccaldi¹, Francesca Tirelli², Anna Cuberli¹, Andrea Benini¹, Meneghel Alessandra², Andrea Doria¹, Francesco Zulian², Elisabetta Zanatta¹ | ¹U.O.C. Reumatologia, Dipartimento di Medicina DIMED, Università degli Studi di Padova Padova, Italy; ²U.O.S.D. Reumatologia Pediatrica, Dipartimento per la Salute della Donna e del Bambino, Azienda Ospedaliera di Padova, Italy

Società Italiana di Reumatologia

DOI https://doi.org/10.4081/reumatismo.2025.2364
- 192 abstract views
PO:30:157 | Radiographic assessment of measurable osteoarticular damage in juvenile idiopathic arthritis (JIA) patients transitioning to adult care

Serena Pastore⁴, Marta Klanmjsceck³, Andrea Guiotto¹, Laura De Nardi^5|6, Alessia Pin⁴, Lorenzo Cereser^1|2, Andrea Taddio^3|4, Luisa Occhipinti¹, Luca Quartuccio^1|2, Alberto Tommasini^3|4, Alen Zabotti² | ¹Università degli Studi di Udine Udine, Italy; ²Ospedale Santa Maria della Misericordia Udine, Italy; ³Università degli Studi di Trieste Trieste, Italy; ⁴IRCCS Materno Infantile Burlo Garofolo Trieste, Italy; ⁵Università Tor Vergata Roma, Italy; ⁶Ospedale Pediatrico Bambino Gesù Roma, Italy

Società Italiana di Reumatologia

DOI https://doi.org/10.4081/reumatismo.2025.2365
- 246 abstract views
PO:30:160 | A rare case of juvenile systemic sclerosis

Marta Arese^1|2, Francesco Baldo³, Stefania Costi³, Achille Marino³, Cecilia Chighizola^1|3, Roberto Felice Caporali^1|2 | ¹Azienda Ospedaliera Universitaria Senese, Università degli Studi di Siena; ²Reumatologia Clinica, ASST Gaetano Pini-CTO, Milano, Italy

Società Italiana di Reumatologia

DOI https://doi.org/10.4081/reumatismo.2025.2203
- 406 abstract views
PO:31:161 | First-line diagnostic tests to intercept primary heart involvement in systemic sclerosis: clinical associations from the SPRING-SIR registry

Antonio Tonutti^1|2, Francesca Motta^1|2, Rossella De Angelis³, Valeria Riccieri⁴, Silvia Laura Bosello⁵, Fabio Cacciapaglia⁶, Veronica Codullo⁷, Giacomo De Luca⁸, Francesca Ingegnoli⁹, Dilia Giuggioli¹⁰, Clodoveo Ferri¹⁰, Marco Matucci-Cerinic⁸, Carlo Selmi^1|2, Maria De Santis^1|2 | ¹Department of Biomedical Sciences, Humanitas University Pieve Emanuele, Milan, Italy; ²Rheumatology and Clinical Immunology, IRCCS Humanitas Research Hospital Rozzano, Milan, Italy; ³Università Politecnica delle Marche Ancona, Italy; ⁴Università degli Studi di Roma La Sapienza Roma, Italy; ⁵Università Cattolica del Sacro Cuore Roma, Italy; ⁶Università degli Studi di Bari Aldo Moro Bari, Italy; ⁷Reumatologia, Fondazione IRCCS Policlinico San Matteo Pavia, Italy; ⁸Università Vita-Salute San Raffaele Milano, Italy; ⁹Università degli Studi di Milano, Italy; ¹⁰Università degli Studi di Modena e Reggio Emilia, Italy

Società Italiana di Reumatologia

DOI https://doi.org/10.4081/reumatismo.2025.2366
- 189 abstract views
PO:31:163 | Safety and tolerability of home-based prostacyclin analogue therapy in vascular manifestations of the scleroderma spectrum: results of a monocentric study

Alice Dionisi¹, Lucrezia Verardi², Annacarla Finucci², Paola Volpe², Anna Cinzia Raspa², Paola Cipriani¹, Raffaele Zicolella² | ¹Reumatologia,Dipartimento di Sscienze Cliniche Applicate e Biotecnologiche, Università degli Studi dell'Aquila; ²UOC Reumatologia, Ospedale Civile di Pescara, Italy

Società Italiana di Reumatologia

DOI https://doi.org/10.4081/reumatismo.2025.2204
- 358 abstract views
PO:31:165 | Prevalence and incidence of skin telangectasia and their association with clinical features: analysis of the European Scleroderma Trials and Research cohort

Gemma Lepri¹, Lorenzo Tofani², Silvia Bellando Randone¹, Veronica Batani³, Paolo Airò⁴, Patricia Carreira⁵, Joerg Henes⁶, Alexandra Balbir Gurman⁷, Florenzo Iannone⁸, Antonella Marcoccia⁹, Luc Mouthon¹⁰, Branimir Anic¹¹, Carolina De Souza Müller¹², Armine Haroyan¹³, Ana Cristina Cordeiro¹⁴, Serena Guiducci And Eustar Coll¹. | ¹University of Florence, Dept of Experimental and Clinical Medicine, AOU Careggi, Division of Rheumatology Florence Italy; ²University of Florence, Dept of Statistics, Informatics, Applications, Florence, Italy; ³Unit of Immunology, Rheumatology, Allergy and Rare Diseases ^UnIRAR, IRCCS San Raffaele, Milano, Italy; ⁴Scleroderma Unit, UOC Rheumatology and Clinical Immunology, ASST Spedali Civili, Brescia, Italy; ⁵Dept of Rheumatology, 12 de Octubre University Hospital, Madrid, Spain; ⁶Centre for Interdisciplinary Rheumatology, Immunology and autoimmune diseases INDIRA, University Hospital Tuebingen, Tuebingen, Germany; ⁷Rheumatology Institute, Rambam Health Care Campus Haifa Israel; ⁸Dept of Precision and Regenerative Medicine and Ionian Area, University of Bari, Bari, Italy; ⁹Interdisciplinary Reference Center for Systemic Sclerosis ^CRIIS Sandro Pertini Hospital, Rome, Italy; ¹⁰Dept of Internal Medicine, Cochin Hospital, Paris Cité University, Paris, France; ¹¹Div Clinical Immunology and Rheumatology, Dept Internal Medicine, School of Medicine, University Hospital Center Zagreb, Zagreb, Croatia; ¹²Rheumatology Division, Hospital de Clínicas da Universidade Federal do Parana, Curitiba, Brazil; ¹³Dept of Rheumatology, Yerevan State Medical University of Armenia, Yerevan, Armenia; ¹⁴Servico Reumatologia Hospital Garcia de Orta Almada, Almada, Portugal.

Società Italiana di Reumatologia

DOI https://doi.org/10.4081/reumatismo.2025.2070
- 320 abstract views
PO:31:166 | S'/PAPs ratio in systemic sclerosis: a promising non-invasive index for early detection and prognosis of pulmonary hypertension. A step toward more accurate screening?

Marco De Pinto¹, Amelia Spinella¹, Pierluca Macripò², Alessia Laneri¹, Benedetta Bongiovanni¹, Maria Grazia Malandra¹, Martina Orlandi^1-3, Gianluca Pagnoni², Arianna Maini², Rosario Rossi^2-4, Clodoveo Ferri¹, Francesca Coppi^2-3, Dilia Giuggioli^1-3. | ¹Rheumatology Unit, Azienda Ospedaliero-Universitaria Policlinico di Modena, University of Modena and Reggio Emilia, Modena, Italy; ²Cardiology Division, Azienda Ospedaliero-Universitaria Policlinico di Modena, Modena, Italy; ³Department of Medical and Surgical Sciences for Children and Adults, University of Modena and Reggio Emilia, Modena, Italy; ⁴Department of Biomedical, Metabolic and Neural Sciences, University of Modena and Reggio Emilia, Modena, Italy.

Società Italiana di Reumatologia

DOI https://doi.org/10.4081/reumatismo.2025.2071
- 345 abstract views
PO:31:167 | Increased M2 pro-fibrotic marker expression in circulating monocytes and cultured monocyte-derived macrophages in systemic sclerosis patients with progressive interstitial lung disease

Vanessa Smith^1|2, Stefano Soldano³, Rosanna Campitiello^3|5, Emanuele Gotelli^3|4, Paola Montagna³, Elvis Hysa^3|5, Tamara Vojinovic^3|4, Carmen Pizzorni^3|4, Sabrina Paolino^3|4, Alberto Sulli^3|4, Maurizio Cutolo^3|4. | ¹Department of Internal Medicine and Department of Rheumatology, Ghent University Hospital, Ghent, Belgium; ²Unit for Molecular Immunology and Inflammation, VIB Inflammation Research Centre, Ghent, Belgium; ³Laboratory of Experimental Rheumatology and Academic Division of Clinical Rheumatology, Department of Internal Medicine, Genova, Italy; ⁴IRCCS Ospedale Policlinico San Martino, Genova, Italy; ⁵Department of Experimental Medicine DIMES, University of Genova, Genova, Italy.

Società Italiana di Reumatologia

DOI https://doi.org/10.4081/reumatismo.2025.2072
- 329 abstract views
PO:31:168 | Risk factors for cancer in systemic sclerosis, impact on disease phenotype and prognosis, and proposal of machine learning-based personalized screening strategies: insights from an EUSTAR study

Antonio Tonutti^1|2, Francesca Motta^1|2, Stefano Erba^1|2, Britta Maurer³, Cristiana Sieiro Santos³, Duygu Temiz Karadag³, Elena Rezus³, Elisabetta Zanatta³, Fabiola Atzeni³, Francesco Benvenuti³, Gabor Kumanovics³, Gabriella Szucs³, Gianluca Moroncini³, Gonçalo Boleto³, Leila Caillault³, Lilian Maria Lopez Nunez³, Masataka Kuwana³, Massimiliano Limonta³, Maurizio Cutolo³, Oliver Distler³, Radim Bevcar³, Roberto Giacomelli³, Rossella De Angelis³, Serena Guiducci³, Stefano Stano³, Valeria Riccieri³, Yasser El Miedany³, Sophie Blaise³, Carlo Selmi^1|2, Maria De Santis^1|2 | ¹Department of Biomedical Sciences, Humanitas University Pieve Emanuele, Milan, Italy; ²Rheumatology and Clinical Immunology, IRCCS Humanitas Research Hospital Rozzano, Milan, Italy; ³EUSTAR collaborators EUSTAR * OTHER

Società Italiana di Reumatologia

DOI https://doi.org/10.4081/reumatismo.2025.2367
- 107 abstract views
PO:31:169 | From Crisis to Chronicity: A Real-World Study of Renal Dysfunction in Systemic Sclerosis

Stefano Stano¹, Fabio Cacciapaglia^1|2, Giorgia Campanale¹, Simone Perniola¹, Maria Morrone¹, Andrea Cito¹, Vincenzo Venerito¹, Maria Grazia Anelli¹, Giuseppe Lopalco¹, Florenzo Iannone¹ | ¹Rheumatology Unit - Department of Precision and Regenerative Medicine, Jonian Area DiPReMeJ, University of Bari Bari, Italy; ²Rheumatology Service, Internal Medicine Unit F. Miulli General Hospital, Department of Medicine and Surgery, LUM Casamassima, Italy

Società Italiana di Reumatologia

DOI https://doi.org/10.4081/reumatismo.2025.2368
- 116 abstract views
PO:31:171 | Uncovering subclinical cardiac involvement in VEDOSS: An echocardiographic driven study

Eugenio Capparelli¹, Eleonora Zaccara¹, Irene Rota², Sara Facetti², Daniela Bompane¹, Laura Castelnovo¹, Antonino Mazzone³, Paola Faggioli¹ | ¹UOC Reumatologia, ASST Ovest-Milanese, Legnano Milano Italy; ²UOC Cardiologia, ASST Ovest-Milanese, Legnano Milano, Italy; ³UOC Medicina Interna, ASST Ovest-Milanese, Legnano, Milano, Italy

Società Italiana di Reumatologia

DOI https://doi.org/10.4081/reumatismo.2025.2369
- 99 abstract views
PO:31:172 | Age and timing of onset of Raynaud's phenomenon and first non-Raynaud sign/symptom as prognostic factors in systemic sclerosis: a retrospective analysis from the systemic sclerosis progression investigation registry of the Italian Society for Rheumatology

Silvia Peretti¹, Cosimo Bruni², Silvia Laura Bosello³, Fabio Cacciapaglia^4-5, Corrado Campochiaro^6-7, Veronica Codullo⁸, Lorenzo Dagna^6-7, Rossella De Angelis⁹, Giacomo De Luca^6-7, Dilia Giuggioli¹⁰, Serena Guiducci¹, Florenzo Iannone⁴, Francesca Ingegnoli¹¹, Valeria Riccieri¹², Marco Matucci Cerinic^6-7, Clodoveo Ferri^10-13, Silvia Bellando Randone¹. | ¹Division of Rheumatology, Scleroderma Unit, Department of Experimental and Clinical Medicine, University of Florence, AO, Firenze, Italy; ²Division of Rheumatology, University Hospital Zurich, University of Zurich, Zurich, Switzerland; ³Rheumatology Division, Catholic University of the Sacred Heart, Fondazione Policlinico Universitario A. Gemelli- IRCCS, Roma, Italy; ⁴Rheumatology Unit, Department of Precision and Regenerative Medicine-Ionian Area, University of Bari Aldo Moro, Bari, Italy; ⁵Reumatology Service, Internal Medicine Unit F.Miulli General Hospital, Acquaviva delle Fonti -Department of Medicine a, Bari, Italy; ⁶Unit of Immunology, Rheumatology, Allergy and Rare Diseases UnIRAR, Inflammation, Fibrosis and Ageing initiative INFL, Milano, Italy; ⁷Vita-Salute San Raffaele University, Milano, Italy; ⁸Department of Internal Medicine and Therapeutics, Università di Pavia, Italy; Division of Rheumatology, Fondazione IRCCS, Pavia, Italy; ⁹Rheumatology Unit, Department of Clinical and Molecular Sciences, Polytechnic University of Marche, Ancona, Italy; ¹⁰Rheumatology Unit, School of Medicine, University of Modena and Reggio Emilia, Modena, Italy; ¹¹Division of Clinical Rheumatology, ASST Pini, Dept. of Clinical Sciences and Community Health, Research Center for Adul, Milano, Italy; ¹²Department of Rheumatology, Sapienza University of Rome, Roma, Italy; ¹³Rheumatology Clinic Madonna dello Scoglio Crotonei, Crotone, Italy.

Società Italiana di Reumatologia

DOI https://doi.org/10.4081/reumatismo.2025.2073
- 511 abstract views
PO:31:173 | Methotrexate monotherapy in early systemic sclerosis: a real-life monocentric Italian experience

Claudia Iannone^1|2, Ilaria Magi^1|2, Antonina Minniti², Giuseppe Armentaro², Silvia Cavalli^1|2, Manuel Sette^1|2, Laura Giudice^1|2, Maria Rosa Pellico^1|2, Cristina Bochicchio^1|2, Roberto Felice Caporali^1|2, Nicoletta Del Papa^1|2. | ¹Dipartimento di Scienze Cliniche e di Comunità, Università degli Studi di Milano, Milano, Italy; ²Dipartimento di Reumatologia e Scienze Mediche, ASST G. Pini-CTO, Milano, Italy.

Società Italiana di Reumatologia

DOI https://doi.org/10.4081/reumatismo.2025.2074
- 367 abstract views
PO:31:174 | Increased frequency of anti-RNA polymerase 3 antibodies in patients with systemic sclerosis and silicone breast implants: a multicentre study from the international European Scleroderma Trials and Research cohort

Maria Grazia Lazzaroni¹, Yolanda Braun-Moscovici², Elda Piovani¹, Claudia Barison¹, Liala Moschetti¹, Veronica Batani³, Corrado Campochiaro³, Michal Tomcik⁴, Francesca Motta⁵, Maria De Santis⁵, Petros P. Sfikaki⁶, Masataka Kuwana⁷, Brigitte Granel⁸, Roberta Foti⁹, Virginia Berlingiero¹⁰, Joana Caetano¹¹, Yannick Allanore¹², Alexandra Balbir-Gurman², Marco Matucci Cerinic³, Franco Franceschini¹, Paolo Airò¹. | ¹ASST Spedali Civili of Brescia, University of Brescia, Brescia, Italy; ²Rambam Health Care Campus, Rappaport Faculty of Medicine, Technion-Israeli Institute of Tecnology, Haifa, Israel; ³Vita-Salute San Raffaele University, San Raffaele Hospital, Milano, Italy; ⁴Institute of Rheumatology, Praga, Czech Republic; ⁵IRCCS Humanitas Research Hospital; Humanitas University, Milano, Italy; ⁶Joint Rheumatology Program, Medical School, National Kapodistrian University of Athens Atene GREECE; ⁷Nippon Medical School Hospital Tokyo Japan; ⁸Hôpital Nord de Marseille; Aix-Marseille Université Marsiglia France; ⁹AOU Policlinico G. Rodolico San Marco, Catania, Italy; ¹⁰Azienda Ospedaliera Universitaria Senese, Siena, Italy; ¹¹Fernando Fonseca Hospital, Amadora, Portugal; ¹²Université Paris Cité, Cochin Hospital, Parigi, France.

Società Italiana di Reumatologia

DOI https://doi.org/10.4081/reumatismo.2025.2075
- 328 abstract views
PO:31:175 | Characterizing gastrointestinal involvement in systemic sclerosis: insights from the national systemic sclerosis progression investigation registry of the Italian Society of Rheumatology

Francesco Bonomi¹, Cosimo Bruni^1|2, Silvia Laura Bosello³, Fabio Cacciapaglia^4|5, Corrado Campochiaro⁶, Roberto Caporali⁷, Veronica Codullo⁸, Maria Antonietta D'Agostino³, Lorenzo Dagna⁶, Rossella De Angelis⁹, Giacomo De Luca⁶, Dilia Giuggioli¹⁰, Serena Guiducci¹, Florenzo Iannone⁴, Francesca Ingegnoli⁷, Carlomaurizio Montecucco⁸, Valeria Riccieri¹¹, Clodoveo Ferri¹⁰, Marco Matucci Cerinic⁶, Silvia Bellando Randone¹. | ¹Scleroderma Unit, Division of Rheumatology AOUC, and Department of Experimental and Clinical Medicine, Uni. of Florence, Firenze, Italy; ²Department of Rheumatology, University Hospital Zurich, University of Zurich Zurigo Switzerland; ³UOC of Rheumatology and Clinical Immunology, Catholic University of the Sacred Heart, Fondazione Policlinico A. Gemelli, Roma, Italy; ⁴Rheumatology Unit, Department of Emergency Surgery and Organ Transplantations, University of Bari, Bari, Italy; ⁵Rheumatology Service, F. Miulli General Hospital - Department of Medicine and Surgery, LUM 'G. De Gennaro', Casamassima, Italy; ⁶Unit of Immunology, Rheumatology, Allergy and Rare Diseases and Inflammation, fibrosis and ageing initiative, UniSR, Milano, Italy; ⁷Division of Clinical Rheumatology, ASST Pini and Università degli studi di Milano, Milano, Italy; ⁸Department of Rheumatology, Policlinico San Matteo, Pavia, Italy; ⁹Rheumatology Unit, Department of Clinical and Molecular Sciences, Polytechnic University of Marche, Ancona, Italy; ¹⁰Rheumatology Unit, School of Medicine, University of Modena and Reggio Emilia, Modena, Italy; ¹¹Department of Rheumatology, Sapienza University of Rome, Roma, Italy.

Società Italiana di Reumatologia

DOI https://doi.org/10.4081/reumatismo.2025.2076
- 499 abstract views
PO:32:176 | Outcomes of upfront combination vs monotherapy with rituximab or mycophenolate mofetil for systemic sclerosis interstitial lung disease: results from a European Scleroderma Trials and Research cohort study

Devis Benfaremo¹, Corrado Campochiaro², Gábor Kumánovics³, Christina Bergmann⁴, Elisabetta Zanatta⁵, David Launay⁶, Serena Guiducci⁷, Mickael Martin⁸, Carolina De Souza Müller⁹, Carlomaurizio Montecucco¹⁰, Luc Mouthon¹¹, Gabriella Szucs¹², Kastriot Kastrati¹³, Marie-Elise Truchetet¹⁴, Madelon Vonk¹⁵, Francesco Del Galdo¹⁶, Marco Matucci-Cerinic², Gianluca Moroncini¹, Yannick Allanore¹⁷. | ¹Department of Clinical and Molecular Sciences, Marche Polytechnic University, Marche University Hospital, Ancona, Italy; ²Vita-Salute San Raffaele University, San Raffaele Hospital, Milano, Italy; ³University of Pécs, Department Of Rheumatology And Immunology, Pécs, Hungary; ⁴University Hospital Erlangen, Department Internal Medicine 3, Erlangen, Germany; ⁵Padova University Hospital, Rheumatology Unit, Padova, Italy; ⁶Univ. Lille, Inserm, CHU Lille, Department of Internal Medicine and Clinical Immunology, Lille, France; ⁷University of Florence, Azienda Ospedaliera Universitaria Careggi, Firenze, Italy; ⁸Poitiers University Hospital, Department of Internal Medicine Poitiers France; ⁹Hospital de Clinicas da Universidade Federal do Parana Curitiba Brazil; ¹⁰Università di Pavia e IRCCS Fondazione Policlinico S. Matteo, Pavia, Italy; ¹¹Hôpital Cochin, Department of Internal Medicine, Paris, France; ¹²University of Debrecen, Faculty of Medicine, Department of Rheumatology, Debrecen, Hungary; ¹³Medical University of Vienna, Department of Medicine III, Division of Rheumatology, Vienna, Austria; ¹⁴CHU de Bordeaux, Rheumatology department, Bordeaux, France; ¹⁵Radboudumc, Department of Rheumatology Nijmegen The Netherlands; ¹⁶Leeds Raynauds and Scleroderma Program, NIHR Biomedical Research Centre, Leeds, United Kingdom; ¹⁷Université Paris Cité, Cochin Hospital, Rheumatology Department, Paris, France.

Società Italiana di Reumatologia

DOI https://doi.org/10.4081/reumatismo.2025.2077
- 434 abstract views
PO:32:178 | Effectiveness of oral anticoagulants in precapillary pulmonary hypertension associated with systemic sclerosis: a EUSTAR cohort study

Nicola Farina¹, Silvia Bellando-Randone¹, Hilde Jenssen-Bjørkekjær², David Launay³, Patricia Carreira⁴, Paolo Airò⁵, Serena Guiducci¹, Dilia Giuggioli⁶, Gabriela Riemekasten⁷, Carmen-Pilar Simeón Aznar⁸, Christina Bergmann⁹, Elise Siegart¹⁰, Ivan Castellví¹¹, Lesley Ann Saketkoo¹², Jeska De Vries-Bouwstra¹³, Philipp Klemm¹⁴, Ulf Müller-Ladner¹⁴, Alexandra Balbir-Gurman¹⁵, Vanessa Smith¹⁶, Florenzo Iannone¹⁷, Luca Idolazzi¹⁸, Christopher Denton¹⁹, Edoardo Rosato²⁰, Britta Maurer¹, Yannick Allanore¹, Yoshiya Tanaka¹, Elisabetta Zanatta¹, Oliver Distler¹, Marco Matucci-Cerinic¹, Cosimo Bruni¹ | ¹Department of Experimental and Clinical Medicine, Scleroderma Unit, Division of Rheumatology, University of Florence, Az Firenze, Italy; ²Department of Rheumatology, Hospital of Southern Norway Kristiansand, Norway; ³National Reference Center for Pulmonary Arterial Hypertension Pulmotension Lille, France; ⁴Hospital Universitario 12 de Octubre, Rheumatology Department Madrid Spain; ⁵ASST Spedali Civili of Brescia, University of Brescia, Rheumatology and Clinical Immunology Unit Brescia, Italy; ⁶Scleroderma Unit, Rheumatology Unit, University Hospital of Modena and Reggio Emilia Modena, Italy; ⁷Universitätsklinikum Schleswig-Holstein, Klinik für Rheumatologie und klinische Immunologie Lübeck Germany; ⁸Hospital Universitario Vall d'Hebron, Department of Internal Medicine, Systemic Autoimmune Diseases Unit Barcelona Spain; ⁹University Hospital Erlangen, Department Internal Medicine 3 Erlangen Germany; ¹⁰Charité University Hospital, Department of Rheumatology Berlin Germany; ¹¹Hospital de la Santa Creu i Sant Pau Baercelona Spain; ¹²New Orleans Scleroderma and Sarcoidosis Patient Care and Research Center New Orleans, USA; ¹³Leiden University Medical Center, Department of Rheumatology Leiden, The Netherlands; ¹⁴JLU Giessen, Campus Kerckhoff, Department of Rheumatology and Clinical Immunology Center Bad Nauheim Germany; ¹⁵Rambam Health Care Campus, Rheumatology Institute Haifa, Israel; ¹⁶University of Ghent, Department of Rheumatology Ghent, Belgium; ¹⁷Rheumatology DiMePReJ, University of Bari, School of Medicine Bari, Italy; ¹⁸University of Verona, Section of Rheumatology, Department of Medicine Verona, Italy; ¹⁹Royal Free London and University College London Medical School, Centre for Rheumatology London, United Kingdom; ²⁰Sapienza University of Rome, Department of Translational and Precision Medicine Azienda Ospedaliero-Universitaria Policl Roma, Italy

Società Italiana di Reumatologia

DOI https://doi.org/10.4081/reumatismo.2025.2370
- 136 abstract views
PO:32:180 | Clinical and hemodynamic profile of patients with SSC-PAH with and without pulmonary veno-occlusive disease: a single-center study

Anna Cuberli¹, Michele Strosio², Alessandro Magi², Beatrice Moccaldi¹, Marco Binda¹, Andrea Benini¹, Andrea Doria¹, Martina Perazzolo Marra², Giulia Famoso², Laura De Michieli², Elisabetta Zanatta^1|2 | ¹UOC Reumatologia, DIDAS Medicina Dei SIstemi, Azienda Ospedale Università di Padova; ²UOC Cardiologia, DIDAS Medicina Dei Sistemi, Azienda Ospedale Università di Padova, Italy

Società Italiana di Reumatologia

DOI https://doi.org/10.4081/reumatismo.2025.2205
- 284 abstract views
PO:32:181 | Digital ulcers predict enhanced Peak Systolic Velocities at internal and external Carotid in Systemic Sclerosis Patients

Eugenio Capparelli¹, Francesco Lapia², Luca Clerici², Eleonora Zaccara¹, Giusy Cinzia Moltisanti², Francesca Capelli², Daniela Bompane¹, Paola Faggioli¹, Antonino Mazzone² | ¹UOC Reumatologia, ASST Ovest Milanese, Legnano, Milano, Italy; ²UOC Medicina Interna, ASST Ovest Milanese, Legnano, Milano, Italy

Società Italiana di Reumatologia

DOI https://doi.org/10.4081/reumatismo.2025.2371
- 95 abstract views
PO:32:182 | Disease characteristics of anti-centromere positive systemic sclerosis patients and risk factors for organ involvement: data from the EUSTAR cohort

Corrado Campochiaro¹, Jelena Colic², Del Papa Nicoletta³, Oliver Distler⁴, Serena Guiducci⁵, Florenzo Iannone⁶, David Launay⁷, Yair Levy⁸, Britta Maurer⁹, Arsene Mekinian¹⁰, Predrag Ostojic², Gabriela Riemekasten¹¹, Petros Sfikakis¹², Bojana Stamenkov¹³, Ulrich Walker¹⁴, Marie Elise Truchetet¹⁵, Madelon Vonk¹⁶, Francesco Del Galdo¹⁷, Giacomo De Luca¹, Lorenzo Dagna¹, Marco Matucci Cerinic¹, Yannick Allanore¹⁸ | ¹IRCCS San Raffaele Hospital; Vita Salute San Raffaele University Milan, Italy; ²University of Belgrade Belgrade, Serbia; ³UOC Reumatologia Clinica, ASST G. Pini CTO Milan, Italy; ⁴University Hospital Zurich Zurich, Switzerland; ⁵Department of Rheumatology, University of Florence Florence, Italy; ⁶Rheumatology Unit Bari, Italy; ⁷CHU Lille Lille, France; ⁸Department of Medicine Kfar Saba, Israel; ⁹Department for BioMedical Research, University of Bern Bern, Switzerland; ¹⁰Service de medecine interne Paris, France; ¹¹Department of Rheumatology University of Lubeck Lubeck Germany; ¹²National and Kapodistrian University of Athens Athens, Greece; ¹³University School of Medicine, Nis Nis, Serbia; ¹⁴University Hospital Basel, Basel Basel, Switzerland; ¹⁵Bordeaux Hospital and University Bordeaux, France; ¹⁶Radboud University Nijmegen Medical Centre, Nijmegen, The Netherlands; ¹⁷Leeds Institute of Rheumatic and Muskuloskeletal Medicine Leeds, United Kingdom; ¹⁸Cochin Hospital Paris, France

Società Italiana di Reumatologia

DOI https://doi.org/10.4081/reumatismo.2025.2372
- 343 abstract views
PO:32:183 | Innovative use of integra dermal regeneration template on systemic sclerosis digital ulcers: a case report

Elena Vanni¹, Martina Orlandi^1|2, Amelia Spinella², Valentina Pinto³, Massimo Pinelli³, Dilia Giuggioli^1|2 | ¹Reumatologia, Università di Modena e Reggio Emilia; ²Reumatologia, Azienda Ospedaliero-Universitaria Policlinico di Modena; ³Chirurgia Plastica, Università di Modena e Reggio Emilia e Azienda Ospedaliero-Universitaria, Policlinico di Modena, Italy

Società Italiana di Reumatologia

DOI https://doi.org/10.4081/reumatismo.2025.2206
- 320 abstract views
PO:32:184 | Assessing the burden of Sars-Cov2 in systemic sclerosis-related interstitial lung disease patients: functional, clinical and therapeutic outcomes from an Italian cohort, a retrospective study

Andrea Cito¹, Greta Giulia Dipietrangelo¹, Daniele V. A. Sabella¹, Marco Fornaro¹, Fabio Cacciapaglia¹, Giuseppe Lopalco¹, Florenzo Iannone¹. | ¹AOUC Policlinico di Bari - Reumatologia Universitaria, Bari, Italy.

Società Italiana di Reumatologia

DOI https://doi.org/10.4081/reumatismo.2025.2078
- 324 abstract views
PO:32:185 | Deep-learning analysis of high-resolution computed tomography images predicts progression and mortality in systemic sclerosis related interstitial lung disease

Valentina Boni¹, Rosa D'Abronzo², Piergiacomo Cerasuolo¹, Lucio Calandriello², Giuseppe Cicchetti², Gerlando Natalello¹, Bruno Iovene⁵, Francesco Varone⁵, Giacomo Sgalla⁵, Luca Richeldi⁵, Anna Rita Larici^2|4, Maria Antonietta D'Agostino^1|3, Silvia Laura Bosello^1|3, Enrico De Lorenzis¹. | ¹Division of Rheumatology and Clinical Immunology Catholic Univeristy of the Sacred Heart, Rome, Italy; ²Department of Diagnostic Imaging, Oncological Radiotherapy and Hematology, Diagnostic Imaging Area, Catholic University, Rome, Italy; ³Department of Geriatric and Orthopaedic Sciences, Catholic Univeristy of the Sacred Heart, Rome, Italy; ⁴Department of Radiological and Hematological Sciences, Section of Radiology, Catholic Univeristy of the Sacred Heart, Rome, Italy; ⁵Division of Pulmonary Medicine, Catholic University of the Sacred Heart, Roma, Italy.

Società Italiana di Reumatologia

DOI https://doi.org/10.4081/reumatismo.2025.2079
- 295 abstract views
PO:32:187 | AI-assisted reading outperforms visual scoring of pulmonary CT scans to predict interstitial lung disease progression in systemic sclerosis

Francesca Motta¹, Antonio Tonutti¹, Federica Catapano², Gianluca Sellaro², Francesco Amati³, Anna Stainer³, Calogero Messana², Stefano Erba¹, Stefano Aliberti³, Marco Francone², Carlo Selmi¹, Maria De Santis¹ | ¹Humanitas University and IRCCS Humanitas Research Hospital, Department of Rheumatology and Clinical Immunology Rozzano, Milan, Italy; ²IRCCS Humanitas Research Hospital, Department of Radiology Rozzano, Milan, Italy; ³IRCCS Humanitas Research Hospital, Respiratory Unit Rozzano, Milan, Italy

Società Italiana di Reumatologia

DOI https://doi.org/10.4081/reumatismo.2025.2373
- 129 abstract views
PO:32:189 | Salivary gland alterations in systemic sclerosis: a comprehensive ultrasound study and autoantibody correlation

Bixio Riccardo¹, Francesca Pistillo¹, Luca Idolazzi¹, Francesca Nava¹, Beatrice Gabrielli¹, Emanuela Perrucchini², Ombretta Viapiana¹, Maurizio Rossini¹. | ¹Rheumatology Unit, University of Verona VERONA Italy; ²WellAgeing DESENZANO DEL GARDA Italy.

Società Italiana di Reumatologia

DOI https://doi.org/10.4081/reumatismo.2025.2080
- 354 abstract views
PO:33:190 | Travel distance to tertiary healthcare reflects disease severity and medication access in systemic sclerosis patients: insights from the Italian systemic sclerosis progression investigation registry of the Italian Society of Rheumatology

Camilla Teresa Magnanimi¹, Enrico De Lorenzis¹, Gerlando Natalello¹, Fabio Cacciapaglia², Rossella De Angelis³, Edoardo Cipolletta³, Maria Antonietta D'Agostino¹, Veronica Cudullo⁴, Giacomo De Luca⁵, Dilia Giuggioli⁶, Francesca Ingegnoli⁷, Valeria Riccieri⁸, Lorenzo Dagna⁵, Fiorenzo Iannone⁹, Clodoveo Ferri⁶, Marco Matucci Cerinic⁵, Silvia Laura Bosello¹. | ¹Division of Rheumatology and Clinical Immunology, Catholic University of the Sacred Heart, Fondazione Policlinico Univer, Roma, Italy; ²Department of Medicine and Surgery, LUM University Giuseppe De Gennaro Casamassima e Rheumatology Service Miulli Ge, Bari, Italy; ³Rheumatology Unit - Department of Clinical and Molecular Sciences, Polytechnic University of Marche, Ancona, Italy; ⁴Department of Rheumatology, Policlinico San Matteo, Pavia, Italy; ⁵Unit of Immunology, Rheumatology, Allergy and Rare Diseases ^UnIRAR, IRCCS San Raffaele Scientific Institute, Vita-Salu, Milano, Italy; ⁶Rheumatology Unit, School of Medicine, University of Modena and Reggio Emilia, Modena, Italy; ⁷Division of Clinical Rheumatology, ASST Pini, Dept. of Clinical Sciences e Community Health, Research Center for Adult a, Milano, Italy; ⁸Department of Rheumatology, La Sapienza University of Rome, Roma, Italy; ⁹Rheumatology Unit, Department of Precision and Regenerative Medicine and Ionian Area, University of Bari, Bari, Italy.

Società Italiana di Reumatologia

DOI https://doi.org/10.4081/reumatismo.2025.2081
- 392 abstract views
PO:33:191 | Evaluation of the living with pulmonary fibrosis questionnaire in patients with systemic sclerosis associated interstitial lung disease: monocentric results

Claudia Barison¹, Elda Piovani¹, Eleonora Pedretti¹, Eleonora Pazzi¹, Liala Moschetti¹, Ilaria Cavazzana¹, Franco Franceschini¹, Maria Grazia Lazzaroni¹, Paolo Airò¹. | ¹Rheumatology and Clinical Immunology, Scleroderma Unit, ASST Spedali Civili of Brescia, University of Brescia, Brescia, Italy.

Società Italiana di Reumatologia

DOI https://doi.org/10.4081/reumatismo.2025.2082
- 439 abstract views
PO:33:192 | Hand Microvascular Damage Is Associated with Hand Bone Loss in Systemic Sclerosis

Rosanna Campitiello^1|3, Sabrina Paolino^1|2, Andrea Casabella^1|2, Giulia Davoli^1|2, Elisa Caratto^1|2, Emanuele Gotelli^1|2, Elvis Hysa^1|2, Carmen Pizzorni^1|2, Vanessa Smith^4|5, Alberto Sulli^1|2, Maurizio Cutolo^1|2 | ¹1. Laboratory of Experimental Rheumatology and Academic Division of Clinical Rheumatology, Department of Internal Medic Genova, Italy; ²IRCCS Ospedale Policlinico San Martino Genova, Italy; ³Department of Experimental Medicine DIMES, University of Genova Genova, Italy; ⁴Department of Internal Medicine and Department of Rheumatology, Ghent University ^Hospital Ghent, Belgium; ⁵Unit for Molecular Immunology and Inflammation, VIB Inflammation Research Centre, Ghent, Belgium

Società Italiana di Reumatologia

DOI https://doi.org/10.4081/reumatismo.2025.2374
- 139 abstract views
PO:33:193 | Self-reported oropharyngeal dysphagia and swallowing-related quality of life in people with systemic sclerosis: preliminary results of a cross-sectional study

Nikla Pacenti¹, Devis Benfaremo², Federica Lucia Galli², Andrea Colangelo³, Gianluca Moroncini² | ¹Internal Medicine Residency Program, Marche Polytechnic University Ancona, Italy; ²Department of Clinical and Molecular Sciences, Marche Polytechnic University Ancona, Italy; ³Medical student, Marche Polytechnic University Ancona, Italy

Società Italiana di Reumatologia

DOI https://doi.org/10.4081/reumatismo.2025.2375
- 113 abstract views
PO:33:194 | The role of anti-g protein-coupled receptors antibodies in the assessment of systemic sclerosis-primary heart involvement

Beatrice Moccaldi¹, Giovanni Civieri², Annagrazia Cecere², Marco Binda¹, Marta Vadori², Laura Iop², Marta Tonello¹, Anna Cuberli¹, Andrea Benini¹, Emanuele Cozzi², Andrea Doria¹, Francesco Tona², Elisabetta Zanatta^1|2. | ¹Unità di Reumatologia, Dipartimento di Medicina ^DIMED, Università di Padova, Padova, Italy; ²Dipartimento di Scienze Cardio-Toraco-Vascolari e Sanità Pubblica, Università di Padova, Padova, Italy.

Società Italiana di Reumatologia

DOI https://doi.org/10.4081/reumatismo.2025.2083
- 310 abstract views
PO:33:195 | Evaluation of prevalence and role of anti-endothelin type a-receptor and anti-angiotensin ii type 1-receptor antibodies in a cohort of systemic sclerosis patients

Clara Minerba¹, Sara Ferrigno¹, Antonella Grimaldi², Noemi Aprile³, Daniela Costanza², Laura Quarta², Maria Rita Ricciardi², Daniela Stasi³, Paola Conigliaro¹, Alberto Bergamini¹, Eugenio Quarta², Maria Sole Chimenti¹. | ¹U.O.C. Reumatologia, Dipartimento di Medicina dei Sistemi, Università di, Roma, Tor Vergata, Roma, Italy; ²U.O.S.D. Reumatologia, P.O. Vito Fazzi Lecce Italy; ³U.O.C. Patologia clinica e Microbiologia, P.O. Vito Fazzi Lecce Italy.

Società Italiana di Reumatologia

DOI https://doi.org/10.4081/reumatismo.2025.2084
- 323 abstract views
PO:33:197 | Systemic sclerosis and endothelial dysfunction: the passive leg movement technique in the assessment of no-mediated vascular impairment

Silvia Guella¹, Giovanni Baldassarre³, Alessandro Gratton^2|3, Lucrezia Zuccarelli³, Elena Treppo², Emma Di Poi², Bruno Grassi³, Luca Quartuccio^2|3 | ¹SS Reumatologia-CMID Ospedale San Giovanni Bosco, Torino; ²Clinica di Reumatologia Ospedale Santa Maria della Misericordia, ASUFC, Udine; ³Dipartimento di Medicina, Università di Udine, Italy

Società Italiana di Reumatologia

DOI https://doi.org/10.4081/reumatismo.2025.2207
- 353 abstract views
PO:33:199 | Prevalence and clinical associations of antiphospholipid antibodies in patients with systemic sclerosis in the SPRING-SIR registry

Antonio Tonutti^1|2, Ilaria Cavazzana³, Angela Ceribelli^1|2, Maria De Santis^1|2, Giacomo De Luca^4|5, Maria Grazia Lazzaroni³, Franco Franceschini³, Carlo Selmi^1|2, Valeria Riccieri⁶, Silvia Laura Bosello⁷, Fabio Cacciapaglia⁸, Veronica Codullo⁹, Francesca Ingegnoli¹⁰, Dilia Giuggioli¹¹, Rossella De Angelis¹², Clodoveo Ferri¹¹, Marco Matucci-Cerinic^4|5 | ¹Department of Biomedical Sciences, Humanitas Universityce Pieve Emanuele, Milan, Italy; ²Rheumatology and Clinical Immunology, IRCCS Humanitas Research Hospital Rozzano, Milan, Italy; ³Rheumatology and Clinical Immunology - ASST Spedali Civili Brescia - Department of Clinical and Experimental Sciences - Brescia, Italy; ⁴Vita-Salute San Raffaele University Milan, Italy; ⁵Unit of Immunology, Rheumatology, Allergy and Rare Diseases UnIRAR and INFLAGE Initiative, IRCCS San Raffaele Hospital Milan, Italy; ⁶University of Rome La Sapienza Rome, Italy; ⁷Catholic University of Sacred Heart Rome, Italy; ⁸LUM University Bari, Italy; ⁹Rheumatology Unit, Fondazione IRCCS Policlinico San Matteo Pavia, Italy; ¹⁰University of Milan Milan, Italy; ¹¹University of Modena and Reggio Emilia Modena, Italy; ¹²Politechnic University of Marche Ancona, Italy

Società Italiana di Reumatologia

DOI https://doi.org/10.4081/reumatismo.2025.2376
- 113 abstract views
PO:33:200 | Analysis of risk factors associated with vertebral fractures in systemic sclerosis: evidence from the "Sclero-RER" study group

Alessandra Bezzi¹, Federica Lumetti², Martina Orlandi³, Fabio Mascella¹, Maria Cristina Focherini¹, Eugenio Arrigoni⁴, Elena Bravi⁴, Andrea Lo Monaco⁵, Amelia Spinella³, Ottavio Secchi³, Gianluigi Bajocchi⁶, Francesco Girelli⁷, Francesco Ursini⁸, Pierluigi Cataleta⁹, Massimo Reta¹⁰, Alarico Ariani^11|12, Dilia Giuggioli³ | ¹Internal Medicine and Rheumatology Unit, AUSL Romagna, Rimini ²AUSL of Modena and Rheumatology Unit, University Hospital Policlinico of Modena; ³Rheumatology Unit, University of Modena and Reggio Emilia; ⁴Rheumatology Unit, Guglielmo da Saliceto Hospital, Piacenza; ⁵Rheumatology, department of medical sciences, University of Ferrara; ⁶Rheumatology Unit, IRCCS Arcispedale Santa Maria Nuova Reggio Emilia; ⁷Rheumatology Unit, G.B. Morgagni - L. Pierantoni Hospital, Forlì; ⁸Rizzoli Orthopedic Institute, Rheumatology Unit, Department of Biomedical and Neuromotor Sciences, Alma Mater Studiorum Bologna; ⁹Hospital Santa Maria delle Croci, Rheumatology Unit, Department of Internal medicine, AUSL-Romagna Ravenna; ¹⁰Rheumatology Unit, AUSL of Bologna, Sant'Orsola Polyclinic Hospital, AOU IRCCS of Bologna; ¹¹Internal Medicine and Rheumatology Unit, University Hospital of Parma; ¹²AUSL Bologna and University of Bologna, IRCCS Policlinico Sant'Orsola, Bologna, Italy

Società Italiana di Reumatologia

DOI https://doi.org/10.4081/reumatismo.2025.2208
- 260 abstract views
PO:33:201 | Metabolic and functional state of circulating platelets in patients with systemic sclerosis

Annalisa Villa¹, Simona Truglia¹, Francesca Maiorca², Annamaria Sabetta², Ludovica Lombardi², Silvia D'Orso², Lucia Stefanini², Fabrizio Conti¹, Marcella Visentini², Valeria Riccieri¹ | ¹Dipartimento di Scienze Cliniche, Internistiche, Anestesiologiche e Cardiovascolari, Università degli Studi di Roma La Sapienza; ²Dipartimento di Medicina Traslazionale e di Precisione, Università degli Studi di Roma La Sapienza

Società Italiana di Reumatologia

DOI https://doi.org/10.4081/reumatismo.2025.2209
- 292 abstract views
PO:33:202 | Assessment of Retinal Arteriolar Wall-to-Lumen Ratio and Renal Resistive Index in patients with Systemic Sclerosis

Eleonora Pazzi^1|2, Elda Piovani^1|2, Claudia Barison^1|2, Liala Moschetti^1|2, Eleonora Pedretti^1|2, Mariagrazia Lazzaroni^1|2, Carolina De Ciuceis³, Claudia Agabiti-Rosei³, Giacomo Buso^3|4, Paolo Baggi³, Claudia Rossini³, Cristina Bevacqua³, Maria Lorenza Muiesan³, Ilaria Cavazzana¹, Franco Franceschini¹, Paolo Airò² | ¹Rheumatology and Clinical Immunology, ASST Spedali Civili of Brescia, University of Brescia, Brescia, Italy; ²Scleroderma Unit, ASST Spedali Civili of Brescia, Brescia, Italy; ³Department of Clinical and Experimental Sciences, Division of Internal Medicine, ASST Spedali Civili of Brescia, Univers Brescia, Italy; ⁴University of Lausanne, Lausanne Switzerland

Società Italiana di Reumatologia

DOI https://doi.org/10.4081/reumatismo.2025.2377
- 123 abstract views
PO:33:203 | Efficacy and safety of rituximab in eosinophilic fasciitis: report of three cases and systematic literature review

Andrea Benini¹, Beatrice Moccaldi¹, Marco Binda¹, Anna Cuberli¹, Mariangela Favaro¹, Andrea Doria¹, Elisabetta Zanatta¹ | ¹UOC Reumatologia, Azienda Ospedale, Università di Padova, Italy

Società Italiana di Reumatologia

DOI https://doi.org/10.4081/reumatismo.2025.2210
- 435 abstract views
PO:34:204 | Impact of anti-centromere antibodies on immunosuppressive therapy persistence in systemic sclerosis: a single-center case-control study

Martina Salerno¹, Marius Cadar¹, Ilaria Bisconti¹, Francesca Romana Di Ciommo¹, Elena Platania¹, Jacopo Landro¹, Beatrice De Girolamo¹, Davide Mohammad Reza Beigi^1|2, Simona Truglia¹, Fabrizio Conti¹, Valeria Riccieri¹ | ¹Rheumatology unit, AOU and Università di Cagliari; ²Asl Biella, Ospedale degli Infermi, Ponderano (BI), Italy

Società Italiana di Reumatologia

DOI https://doi.org/10.4081/reumatismo.2025.2211
- 338 abstract views
PO:34:205 | Optical coherence tomography angiography: a window on systemic sclerosis microangiopathy

Martina Orlandi¹, Tommaso Verdina², Filippo Santoro¹, Alessandra Carobbio³, Amelia Spinella¹, Marco De Pinto¹, Giorgia Roveta¹, Dilia Giuggioli¹ | ¹Internal Medicine Residency Program, Marche Polytechnic University, Ancona; ²Department of Clinical and Molecular Sciences, Marche Polytechnic University, Ancona; ³Department of Interna, Ancona, Italy

Società Italiana di Reumatologia

DOI https://doi.org/10.4081/reumatismo.2025.2212
- 318 abstract views
PO:34:207 | When the Lungs Speak in Squeaks: Chronic Bird-Related HP in SSc-ILD with Incidental Lymphoma

Mariagrazia Nuara¹, Marco De Pinto², Amelia Spinella², Stefania Cerri^1|2, Enrico Clini^1|2, Dilia Giuggioli^1|2 | ¹Università degli Studi di Modena e Reggio Emilia, Italy; ²AOU, Policlinico di Modena, Italy

Società Italiana di Reumatologia

DOI https://doi.org/10.4081/reumatismo.2025.2378
- 132 abstract views
PO:34:209 | Increased liver stiffness and fibrosis in systemic sclerosis: a single-center transient elastography cohort study.

Nicola Ortalli^1|2, Simone Aldo Lari^1|2, Alessandra Vacca³, Erika Meleddu^1|2, Alberto Civolani⁴, Emanuela Vargiu⁴, Alberto Floris^1|2, Massimo Claudio Fantini⁴, Alberto Cauli^1|2. | ¹Rheumatology Unit, Azienda Ospedaliero Universitaria di Cagliari, Cagliari, Italy; ²Department of Medical Sciences and Public Health, University of Cagliari, Cagliari, Italy; ³Rheumatology Unit, Presidio Ospedaliero CTO di Iglesias Iglesias Italy; ⁴Gastroenterology Unit, Azienda Ospedaliero Universitaria di Cagliari, Cagliari, Italy.

Società Italiana di Reumatologia

DOI https://doi.org/10.4081/reumatismo.2025.2085
- 315 abstract views
PO:34:211 | Gynecological health and ultrasound evaluation among fertile women affected by Systemic sclerosis: an observational study

Martina Orlandi¹, Sofia Gambigliani Zoccoli², Mariagrazia Nuara¹, Riccardo Cuoghi Costantini², Amelia Spinella¹, Marco De Pinto¹, Antonio La Marca², Dilia Giuggioli¹ | ¹Dipartimento di Scienze Mediche e Chirurgiche, Università di Modena e Reggio Emilia, Italy; ²Dipartimento Materno Infantile. Università di Modena e Reggio Emilia, Italy

Società Italiana di Reumatologia

DOI https://doi.org/10.4081/reumatismo.2025.2379
- 138 abstract views
PO:34:212 | Orofacial manifestations in systemic sclerosis: preliminary observational study and update of a single-center experience

Amelia Spinella¹, Marco De Pinto¹, Giacomo Setti², Martina Orlandi^1|3, Samuele Veronesi², Federica Lumetti¹, Alessia Laneri¹, Luca Keller Sarmiento¹, Giorgia Roveta¹, Gilda Sandri^1|3, Pierantonio Bellini², Ugo Consolo², Dilia Giuggioli^1|3 | ¹Università degli Studi di Milano, Dipartimento di Scienze Cliniche e di Comunità, Milano; ²ASST G. Pini-CTO, UOC di Clinica Reumatologica, Milano; ³UOC di Reumatologia Clinica Pediatrica, ASST Gaetano Pini-CTO, Milano, Italy

Società Italiana di Reumatologia

DOI https://doi.org/10.4081/reumatismo.2025.2213
- 291 abstract views
PO:34:214 | Autonomic Symptoms Are Associated with Neuropathic Pain Features and Disease Impact in Systemic Sclerosis: Results From a Cross-Sectional Study

Benedetta Bianchi¹, Francesca Francioso¹, Mariachiara Mangiafico¹, Fausto Salaffi¹, Rossella De Angelis¹, Marco Di Carlo¹ | ¹U.O. Reumatologia, Ospedale Carlo Urbani, Università Politecnica delle Marche Jesi, Italy

Società Italiana di Reumatologia

DOI https://doi.org/10.4081/reumatismo.2025.2380
- 153 abstract views
PO:34:217 | Possible role of phosphodiesterase type 5 inhibitors in the prevention of digital ulcers and videocapillaroscopic changes in patients with systemic sclerosis

Elena Platania¹, Marius Cadar¹, Ilaria Bisconti¹, Davide Mohammad Reza Beigi^1|2, Francesca Romana Di Ciommo¹, Jacopo Landro¹, Martina Salerno¹, Beatrice De Girolamo¹, Simona Truglia¹, Fabrizio Conti¹, Valeria Riccieri¹ | ¹S.C. Reumatologia; ²S.C. Reumatologia

Società Italiana di Reumatologia

DOI https://doi.org/10.4081/reumatismo.2025.2214
- 428 abstract views
PO:35:218 | Switching the dose of mepolizumab in patients with Eosinophilic Granulomatosis with Polyangiitis (EGPA): a European retrospective multicentre real-world study

Edoardo Biancalana¹, Irene Mattioli¹, Emanuele Chiara², Danilo Malandrino¹, Maria Canfora¹, Palmerini Miki¹, Maria Paola Lisi¹, Michela Gasparotto³, Paola Tomietto³, Maria Letizia Urban¹, Giacomo Bagni¹, Elena Silvestri¹, Alessandra Bettiol³, Augusto Vaglio³, Giacomo Emmi² | ¹Department of Experimental and Clinical Medicine, University of Florence Firenze, Italy; ²Department of Medical, Surgery and Health Sciences, University of Trieste Trieste, Italy; ³Clinical Medicine and Rheumatology Unit, Cattinara University Hospital, Trieste, Trieste, Italy; ⁴Department of Biomedical, Experimental and Clinical Sciences Mario Serio, University of Florence Firenze, Italy

Società Italiana di Reumatologia

DOI https://doi.org/10.4081/reumatismo.2025.2381
- 186 abstract views
PO:35:219 | Real-world effectiveness of mepolizumab on gastrointestinal involvement in eosinophilic granulomatosis with polyangiitis and hypereosinophilic syndrome: a multicentre retrospective study

Alessia Gatti¹, Francesca Regola¹, Giulia Fontana¹, Mario Addrea Piga², Gianluca Moroncini², Palma Carlucci³, Angelo Vacca³, Paolo Delvino⁴, Enrico Heffler⁵, Emanuele Nappi⁵, Jakub Moll⁶, Laura Losappio⁶, Jan Schroeder⁶, Federica Davanzo⁷, Roberto Padoan⁷, Edoardo Conticini⁸, Paolo Cameli⁸, Greta Pacini⁹, Alvise Berti⁹, Lorenzo Vrola¹⁰, Paola Tomietto¹⁰, Luca Quartuccio¹¹, Jan Willem Cohen Tervaert¹², Sabrina Arnold¹³, Peter Lamprecht¹³, Florence Roufosse¹⁴, Ilaria Cavazzana¹, Franco Franceschini¹, Giacomo Emmi¹⁵, Paola Toniati¹. | ¹Rheumatology and Clinical Immunology Unit, ERN ReCONNET, ASST Spedali Civili of Brescia and University of Brescia, Italy, Brescia, Italy; ²Università Politecnica delle Marche and Azienda Ospedaliero Universitaria delle Marche, Ancona, Italy, Ancona, Italy; ³Section of Internal Medicine 'Guido Baccelli', DiMePRe-J, University of Bari 'Aldo Moro', Bari, Italy, Bari, Italy; ⁴Rheumatology Unit, IRCCS San Gerardo dei Tintori, Monza, Italy Monza Italy; ⁵Department of Biomedical Sciences, Humanitas University and Personalized Medicine, Asthma and Allergy IRCCS Humanitas, Milano, Italy; ⁶Division of Allergy and Clinical Immunology, ASST GOM Niguarda, Milan, Italy, Milano, Italy; ⁷Rheumatology Unit, Department of Medicine DIMED, University of Padua, Padova, Italy, Padova, Italy; ⁸University of Siena, Siena, Italy, Siena, Italy; ⁹Santa Chiara Hospital and University of Trento, Unit of Rheumatology, Trento, Italy Trento Italy; ¹⁰UCO Medicina Clinica, ASUGI, Cattinara Teaching Hospital, Trieste, Italy, Trieste, Italy; ¹¹Division of Rheumatology, Department of Medicine ^DMED, University of Udine, Udine, Italy, Udine, Italy; ¹²University of Alberta, Edmonton, Alberta, Canada and Maastricht University, Maastricht, The Netherlands Maastricht The Netherlands; ¹³Department of Rheumatology and Clinical Immunology, University of Lübeck, Lübeck, Germany Lubeck Germany; ¹⁴Department of Internal Medicine, Hôpital Universitaire de Bruxelles - Erasme, Université Libre de Bruxelles, Belgium Brussels Belgium; ¹⁵Clinical Medicine and Clinical Immunology and Rheumatology Unit Cattinara University Hospital and University of Trieste, Trieste, Italy.

Società Italiana di Reumatologia

DOI https://doi.org/10.4081/reumatismo.2025.2086
- 442 abstract views
PO:35:220 | IgG anti-pentraxin 3 autoantibodies distinguish eosinophilic granulomatosis with polyangiitis from severe eosinophilic asthma and chronic rhinosinusitis with nasal polyps

Eleonora Fiorin¹, Anna Ghirardello¹, Federica Davanzo¹, Luca Iorio¹, Marta Codirenzi¹, Roberta Prevedello¹, Roberto Padoan¹, Andrea Doria¹. | ¹Università di Padova, Dipartimento di Medicina DIMED, UOC di Reumatologia, Padova, Italy.

Società Italiana di Reumatologia

DOI https://doi.org/10.4081/reumatismo.2025.2087
- 285 abstract views
PO:35:221 | Cryofibrinogen: a cold case. Characteristics and clinical outcomes from a cryofibrinogen positive cohort

Daniele Catameró¹, Andrea Cito¹, Cristiana Colaprico¹, Teresa Caferri¹, Teresa Troiano¹, Anna Marinaccio¹, Marco Fornaro¹, Giuseppe Lopalco¹, Florenzo Iannone¹. | ¹Unit of Rheumatology , Department of Precision and Regenerative Medicine, Area Jonica DiMePRe-J, University of Bari, Bari, Italy.

Società Italiana di Reumatologia

DOI https://doi.org/10.4081/reumatismo.2025.2088
- 290 abstract views
PO:35:222 | Distinctive Features of Localized Vasculitis of the Gastrointestinal Tract Compared to Takayasu Arteritis: Insights from a Multicenter Cohort Study

Vittorio Dibenedetto^1|2|3, Alessandro Tomelleri^1|2, Corrado Campochiaro^1|2, Elena Baldissera^1|2, Luca Moroni^1|2, Padoan Roberto⁴, Marco Matucci-Cerinic^1|2|3, Lorenzo Dagna^1|2|3 | ¹Unit of Immunology, Rheumatology, Allergy and Rare Diseases UNIRAR, IRCCS San Raffaele Hospital Milan, Italy; ²Inflammation, Fibrosis and Ageing Intitiative INFLAGE, IRCCS San Raffaele Hospital Milan, Italy; ³Vita-Salute San Raffaele University, Milan, Italy Milan, Italy; ⁴University Hospital of Padova, Department of Internal Medicine and Rheumatology Padova, Italy

Società Italiana di Reumatologia

DOI https://doi.org/10.4081/reumatismo.2025.2382
- 127 abstract views
PO:35:223 | Biologic therapy for sustained remission in eosinophilic myocarditis: real-world evidence from a tertiary center experience

Federica Davanzo¹, Caterina Menghi², Andrea Silvio Giordani², Anna Baritussio², Federico Scognamiglio², Cristina Vicenzetto², Luca Iorio¹, Renzo Marcolongo², Cristina Basso³, Andrea Doria¹, Roberto Padoan¹, Alida Linda Patr Caforio² | ¹Rheumatology Unit, Department of Medicine, University of Padua Padova, Italy; ²Cardiology Unit, Department of Cardiac, Vascular, Thoracic Sciences and Public Health, University of Padua Padova, Italy; ³Cardiovascular Pathology, Department of Cardiac, Thoracic and Vascular Sciences and Public Health, University of Padua Padova, Italy

Società Italiana di Reumatologia

DOI https://doi.org/10.4081/reumatismo.2025.2383
- 184 abstract views
PO:35:224 | Capturing What BVAS Misses: Patient-Reported Outcomes Reflect Disease Activity and Burden in EGPA

Marta Codirenzi¹, Federica Davanzo¹, Luca Iorio¹, Eleonora Fiorin¹, Roberta Prevedello¹, Roberto Padoan¹, Andrea Doria¹ | ¹Unità di reumatologia, dipartimento di medicina DIMED,Università degli studi di Padova, Italy

Società Italiana di Reumatologia

DOI https://doi.org/10.4081/reumatismo.2025.2384
- 127 abstract views
PO:35:226 | Red flags raising suspicion of Eosinophilic Granulomatosis with Polyangiitis (EGPA): results from the European EGPAware Delphi study

Gabriele Brembilla¹, Bernhard Hellmich^2|3, Apostolos Bossios^4|5, Chistian Domingo-Ribas^6|7, Giacomo Emmi⁸, Cristina Ponte^9|10, Maria Roser Solans-Laque¹¹, Íñigo Jesus Rúa-Figueroa¹², Augusto Vaglio¹³, Dimitrios Vassilopoulos¹⁴, Konstantina Kallinikou¹⁵, Benjamin Terrier¹⁶ | ¹GSK Verona, Italy; ²Medius Klinik Kirchheim Kirchheim unter Teck Germany; ³Teaching Hospital of the University of Tübingen Tübingen Germany; ⁴Karolinska University Hospital Stockholm, Sweden; ⁵Karolinska Institutet Solna, Sweden; ⁶Parc Taulí University Hospital. Parc Taulí Research and Innovation Institute I3PT-CERCA Barcelona Spain; ⁷Department of Medicine, Universitat Autònoma de Barcelona ^UAB Barcelona Spain; ⁸University of Trieste, UNITS, Trieste, Italy; ⁹Santa Maria Hospital Lisbon, Portugal; ¹⁰Lisbon Academic Medical Center Lisbon, Portugal; ¹¹Vall d'Hebron University Hospital Barcelona Spain; ¹²Gran Canaria Doctor Negrín Hospital Las Palmas de Gran Canaria Spain; ¹³University of Florence Florence, Italy; ¹⁴National and Kapodistrian University of Athens School of Medicine Athens, Greece; ¹⁵GSK Athens, Greece; ¹⁶Cochin Hospital Paris, France

Società Italiana di Reumatologia

DOI https://doi.org/10.4081/reumatismo.2025.2385
- 176 abstract views
PO:35:227 | Long-term renal and survival outcomes in microscopic polyangiitis: data from an observational monocentric cohort

Roberta Prevedello¹, Federica Davanzo¹, Luca Iorio¹, Eleonora Fiorin¹, Marta Codirenzi¹, Roberto Padoan¹, Andrea Doria¹. | ¹Unità di Reumatologia, Dipartimento di Medicina DIMED, Università degli Studi di Padova, Padova, Italy.

Società Italiana di Reumatologia

DOI https://doi.org/10.4081/reumatismo.2025.2089
- 320 abstract views
PO:35:228 | Polymyalgia rheumatica and giant cell arteritis induced by immune checkpoint inhibitors for cancer treatment: a systematic review and meta-analysis highlighting differences from the idiopathic forms

Elvis Hysa¹, Andrea Casabella², Emanuele Gotelli¹, Rosanna Campitiello¹, Carlo Genova³, Enrica Teresa Tanda⁴, Carmen Pizzorni¹, Alberto Sulli¹, Vanessa Smith⁵, Marco Amedeo Cimmino⁶, Sabrina Paolino¹, Maurizio Cutolo¹. | ¹Laboratory of Experimental Rheumatology and Academic Division of Clinical Rheumatology, Department of Internal Medicine, Genova, Italy; ²IRCCS Ospedale Policlinico San Martino, Genova, Italy; ³Academic Oncology Unit; IRCCS Ospedale Policlinico San Martino, Genova, Italy; ⁴UOC Medical Oncology Clinic 2, Department of Internal Medicine, University of Genova, Genova, Italy; ⁵Department of Internal Medicine, Ghent University, Department of Rheumatology, Ghent University Hospital, Ghent, Belgium; ⁶Rheumatology Outpatient Clinic, Villa Ravenna Chiavari Italy.

Società Italiana di Reumatologia

DOI https://doi.org/10.4081/reumatismo.2025.2090
- 306 abstract views
PO:35:233 | Tocilizumab is associated with improved relapse-free survival in polymyalgia rheumatica: a multicentre retrospective study

Milena Bond¹, Giovanni Adami², Marianna Tamussin³, Mario Frasca⁴, Sara Zandonella Callegher¹, Marcello Govoni³, Maurizio Rossini², Lorenzo Dagna⁴, Marco Matucci Cerinic⁴, Christian Dejaco¹, Alessandro Tomelleri⁴ | ¹Department of Rheumatology, Brunico Hospital ASAA-SABES, Teaching Hospital of the Paracelsius Medical University Bunico, Italy; ²Rheumatology Unit, University of Verona, Policlinico Borgo Roma Verona, Italy; ³Rheumatology Unit, Department of Medical Sciences, University of Ferrara and Azienda Ospedaliero-Universitaria S. Anna Ferrara, Italy; ⁴Unit of Immunology, Rheumatology, Allergy and Rare Diseases, IRCCS San Raffaele Hospital Milano, Italy

Società Italiana di Reumatologia

DOI https://doi.org/10.4081/reumatismo.2025.2386
- 128 abstract views
PO:35:234 | Sustained Vasculitis Quiescence and CS Reduction with Mepolizumab 100 mg

Francesca Mascia¹, Angelo Fassio², Marco Zurlo¹, Davide Chesini³, Francesco Pollastri², Giovanni Adami², Davide Gatti⁴, Maurizio Rossini⁴, Matteo Maule⁵, Gianentrico Senna¹, Marco Caminati¹ | ¹University of Verona - Allergology and Clinical Immunology Verona, Italy; ²Policlinico G. B. Rossi - Rheumatology Verona, Italy; ³University of Verona - Faculty of Medicine and Surgery Verona, Italy; ⁴University of Verona - Rheumatology Verona, Italy; ⁵Policlinico G. B. Rossi - Allergology and Clinical Immunology Verona, Italy

Società Italiana di Reumatologia

DOI https://doi.org/10.4081/reumatismo.2025.2387
- 122 abstract views
PO:36:238 | Clinical, functional, and radiological similarities between interstitial lung disease–anti–myeloperoxidase and idiopathic pulmonary fibrosis

Enrico Colombo¹, Jessica Gozzi², Paolo Francia³, Giulia Cervi², Marilena Frigato¹, Martina Garuti², Francesca Bartoli¹, Irene Gavioli¹, Caterina Cerbone², Massimiliano Beccaria², Maria Teresa Costantino¹ | ¹SC Allergologia, Immunologia Clinica e Reumatologia, ASST Mantova; ²SC Pneumologia, ASST Mantova; ³SC Radiologia, ASST Mantova, Italy

Società Italiana di Reumatologia

DOI https://doi.org/10.4081/reumatismo.2025.2215
- 311 abstract views
PO:36:242 | Bilateral central retinal artery occlusion as the first manifestation of eosinophilic granulomatosis with polyangiitis during benralizumab therapy

Benedetta Fazzi¹, Elena Treppo¹, Lucia Finocchio², Maria Pillon¹, Luca Quartuccio¹ | ¹Clinica di Reumatologia, Dipartimento di Medicina, Presidio Ospedaliero Universitario Santa Maria della Misericordia, Udine; ²SOC Oculistica, Presidio Ospedaliero Universitario Santa Maria della Misericordia, ASUFC, Udine, Italy

Società Italiana di Reumatologia

DOI https://doi.org/10.4081/reumatismo.2025.2216
- 291 abstract views
PO:36:243 | Drug survival, discontinuation reasons and disease activity in patients with Behçet's disease treated with infliximab - a real-life study

Antonello Sulis¹, Federica Di Cianni¹, Maria Laura Manca², Rosaria Talarico¹, Marta Mosca¹. | ¹Rheumatology Unit of Pisa, University of Pisa, Pisa, Italy, Pisa, Italy; ²Department of Clinical and Experimental Medicine and Department of Mathematics, University of Pisa, Italy, Pisa, Italy.

Società Italiana di Reumatologia

DOI https://doi.org/10.4081/reumatismo.2025.2091
- 358 abstract views
PO:36:244 | Early diagnosis in eosinophilic granulomatosis with polyangiitis: a multidisciplinary approach

Federico Giuseppe Lazzaro¹, Elena Chiaradia², Chiara Lombardi², Flavia Leone¹, Massimo Nucci², Roberta Masnata², Flora Niedda², Maria Rita Gigante¹, Pietro Rubortone¹, Silvia Laura Bosello^1|2, Maria Antonietta D'Agostino^1|2, Augusta Ortolan^1|2. | ¹Divisione di Reumatologia ed Immunologia Clinica, Fondazione Policlinico Universitario A. Gemelli IRCCS, Roma, Italy; ²Università Cattolica del Sacro Cuore, Roma, Italy.

Società Italiana di Reumatologia

DOI https://doi.org/10.4081/reumatismo.2025.2092
- 293 abstract views
PO:36:245 | Uncovering clinical and demographic differences in major organ involvement versus benign Behçet’s disease: insights from a single-centre study

Federica Di Cianni¹, Antonello Sulis¹, Maria Laura Manca², Rosaria Talarico¹, Marta Mosca¹. | ¹Rheumatology Unit, University of Pisa, Pisa, Italy; ²Department of Clinical and Experimental Medicine and Department of Mathematics, University of Pisa, Pisa, Italy.

Società Italiana di Reumatologia

DOI https://doi.org/10.4081/reumatismo.2025.2093
- 314 abstract views
PO:36:246 | Early real-world outcomes with benralizumab in eosinophilic granulomatosis with polyangiitis: a monocentric retrospective

Richard Borrelli¹, Stefania Nicola¹, Federica Corradi¹, Iuliana Badiu¹, Marzia Boem¹, Valentina Marmora¹, Simone Negrini¹, Luisa Brussino¹. | ¹SCDU Immunologia e Allergologia, AO Mauriziano, Dipartimento di Scienze Mediche, Università degli Studi di Torino, Torino, Italy.

Società Italiana di Reumatologia

DOI https://doi.org/10.4081/reumatismo.2025.2094
- 365 abstract views
PO:36:250 | Eosinophilic granulomatosis with polyangiitis associated to Alpha-1 Antitrypsin Deficiency: a land still unexplored

Maria Grazia Malandra¹, Vacchi Caterina¹, Santoro Filippo¹, Cassone Giulia¹, Martina Orlandi¹, Stefania Cerri¹, Dilia Giuggioli¹ | ¹Università di Modena - Reggio Emilia, S.C. Reumatologia Azienda Ospedaliera Universitaria Policlinico di Modena Modena, Italy; ²S.C. Reumatologia Azienda Ospedaliera Universitaria Policlinico di Modena Modena, Italy; ³Università di Modena e Reggio Emilia, S.C. Reumatologia Azienda Ospedaliera Universitaria Policlinico di Modena Modena, Italy; ⁴S.C. Reumatologia Azienda Ospedaliera Universitaria Policlinico di Modena Modena, Italy; ⁵Università di Modena e Reggio Emilia, S.C. Reumatologia Azienda Ospedaliera Universitaria Policlinico di Modena Modena, Italy; ⁶Università di Modena e Reggio Emilia, S.C. Reumatologia Azienda Ospedaliera Universitaria Policlinico di Modena Modena, Italy; ⁷Università di Modena e Reggio Emilia, S.C. Reumatologia Azienda Ospedaliera Universitaria Policlinico di Modena Modena, Italy

Società Italiana di Reumatologia

DOI https://doi.org/10.4081/reumatismo.2025.2388
- 130 abstract views
PO:36:251 | Rheumatoid factor predicts vasculitis relapse in eosinophilic granulomatosis with polyangiitis: a machine learning approach

Luca Iorio¹, Federica Davanzo¹, Giulia Lorenzoni², Eleonora Fiorin¹, Marta Codirenzi¹, Roberta Prevedello¹, Debora Campaniello¹, Dario Gregori², Roberto Padoan¹, Andrea Doria¹. | ¹Rheumatology Unit, DIMED, University of Padova, Padova, Italy; ²Unit of Biostatistics, Epidemiology and Public Health, DCTV, University of Padova, Padova, Italy.

Società Italiana di Reumatologia

DOI https://doi.org/10.4081/reumatismo.2025.2095
- 342 abstract views
PO:36:252 | Long-Term Outcomes of Patients with Takayasu Arteritis in the Era of Biological Agents: a Multicenter International Study

Alessandro Tomelleri¹, Durga Prasanna Misra², Fatma Alibaz-Oner³, Chiara Marvisi⁴, Chiara Calabrese¹, Upendra Rathore², Aysegul Avcu³, Adele Del Giudice⁴, Elisabetta Olivi⁴, Caterina Ricordi⁴, Corrado Campochiaro¹, Elena Baldissera¹, Marco Matucci-Cerinic¹, Haner Direskeneli³, Carlo Salvarani⁴, Lorenzo Dagna¹ | ¹IRCCS Ospedale San Raffaele, Unità di Immunologia, Reumatologia, Allergologia e Malattie Rare Milano, Italy; ²Sanjay Gandhi Postgraduate Institute of Medical Sciences SGPGIMS, Clinical Immunology and Rheumatology Lucknow Country, India; ³Marmara University, School of Medicine, Department of Internal Medicine, Division of Rheumatology Istanbul, Turkey; ⁴Azienda USL-IRCCS di Reggio Emilia, Unità di Reumatologia Reggio Emilia, Italy

Società Italiana di Reumatologia

DOI https://doi.org/10.4081/reumatismo.2025.2389
- 187 abstract views
PO:36:253 | Lifestyle and Behçet's syndrome: a preliminary study on gender differences

Pietro Leccese¹, Angela Anna Padula¹, Nancy Lascaro¹, Salvatore D'Angelo¹, Maria Carmela Padula¹ | ¹UOC Reumatologia AOR San Carlo, Potenza, Italy

Società Italiana di Reumatologia

DOI https://doi.org/10.4081/reumatismo.2025.2217
- 324 abstract views
PO:37:254 | Absence of ciliary artery occlusion does not exclude arteritic anterior ischemic optic neuropathy (A-AION): diagnostic and pathophysiologic implications

Ruggiero Mascolo Mascolo¹, Stefano Erba², Alba Xhepa², Martina Martelli¹, Gabriella Marinaro¹, Giulia Dieguez¹, Giacomo Iacomelli¹, Chiara Facoetti¹, Michel Chevallard³, Bruno Lucchino³, Mariaeva Romano³, Andrea Locatelli³, Giuliana La Paglia³, Donatella Ventura³, Giovanna Randisi³, Alessandra Mutti³, Alessandro Invernizzi², Stefano De Angelis², Giovanni Staurenghi², Antonio Brucato⁴, Enrico Tombetti⁴ | ¹Dipartimento di Medicina Interna, ASST Fatebenefratelli-Sacco, Università degli studi di Milano, Italy; ²U.O. Oculistica, ASST Fatebenefratelli-Sacco Milano, Italy; ³U.O. Reumatologia, ASST Fatebenefratelli-Sacco Milano, Italy; ⁴Dipartimento di Scienze cliniche e biomediche, ASST Fatebenefratelli-Sacco, Università degli studi di Milano, Italy

Società Italiana di Reumatologia

DOI https://doi.org/10.4081/reumatismo.2025.2390
- 118 abstract views
PO:37:256 | Spontaneous renal artery dissection: a subtle presentation of a “vasculitis-mimicker”

Federdo Nogarin¹, Alfonso Valerio Massara¹, Zairo Ferrante², Filippo Furicchia³, Riccardo Bertola¹, Elena Pollicelli¹, Ilaria Calciolari¹, Sopie Secka¹, Andrea Lo Monaco¹, Marcello Govoni¹ | ¹UOC Reumatologia; ²UOC Radiologia Ospedaliera; ³UOC Radiologia Vascolare e Interventistica, Arcispedale Sant'Anna, Ferrara, Italy

Società Italiana di Reumatologia

DOI https://doi.org/10.4081/reumatismo.2025.2218
- 330 abstract views
PO:37:257 | Giant cell arteritis debuting with aortic involvement: the importance of integrated diagnostics in fever of unknown origin

Alessandro Gratton¹, Giovanni Striani¹, Luisa Occhipinti¹, Stefania Sacco¹, Enrico Pegolo², Luca Quartuccio¹ | ¹Rheumatology Clinic and ² Institute of Anatomical Pathology, Department of Laboratory Medicine, University of Udine, Hospital “Santa Maria della Misericordia”, Udine, Italy

Società Italiana di Reumatologia

DOI https://doi.org/10.4081/reumatismo.2025.2219
- 329 abstract views
PO:37:258 | Neutrophil and eosinophil extracellular traps in eosinophilic granulomatosis with polyangiitis: phenotype-based characterization and response to mepolizumab

Michele Moretti¹, Francesco Ferro², Francesco Pisani¹, Elisa Ferrigno¹, Gaetano La Rocca¹, Federica Di Cianni³, Rosaria Talarico², Marta Mosca¹, Chiara Baldini¹, Ilaria Puxeddu¹. | ¹University of Pisa - Department of Clinical and Experimental Medicine, Pisa, Italy; ²Azienda Ospedaliero Universitaria Pisana - Rheumatology Unit, Pisa, Italy; ³University of Siena, Siena, Italy.

Società Italiana di Reumatologia

DOI https://doi.org/10.4081/reumatismo.2025.2096
- 332 abstract views
PO:37:259 | Is there a seasonal pattern in giant cell arteritis? Revisiting the evidence in a large monocentric cohort of 1203 patients

Milena Bond¹, Philipp Bosch², Aaron Juche³, Hans Bastian³, Wolfgang Schmidt⁴. | ¹Department of Rheumatology, Hospital of Bruneck ASAA-SABES, Teaching Hospital of the Paracelsius Medical University Brunico Italy; ²Department of Rheumatology and Immunology, Medical University of Graz, Graz, Austria; ³Medical Centre for Rheumatology Berlin-Buch, Immanuel Krankenhaus Berlin Berlin Germany; ⁴Waldfriede Hospital, Rheumatology, Berlin, Germany.

Società Italiana di Reumatologia

DOI https://doi.org/10.4081/reumatismo.2025.2097
- 261 abstract views
PO:37:260 | Mepolizumab in the treatment of patients with eosinophilic granulomatosis with polyangiitis: real-life experience from a single-center cohort

Eleonora Bruschi¹, Fabrizio Angeli¹, Alessandro Belotti Masserini¹, Stefania Bertocchi¹, Silvia Breda¹, Elide Lupi¹, Valeria Rossi¹, Tania Ubiali¹, Massimiliano Limonta¹ | ¹ASST Papa Giovanni XXIII Bergamo Italy

Società Italiana di Reumatologia

DOI https://doi.org/10.4081/reumatismo.2025.2220
- 314 abstract views
PO:37:263 | First non invasive visualization of vasculitis in the retinal arteries by high resolution optical coherence tomography in a patient with giant cell arteritis

Ruggiero Mascolo¹, Chiara Facoetti¹, Claudia Nardi², Stefano Erba², Martina Martelli¹, Gabriella Marinaro¹, Giulia Dieguez¹, Giacomo Iacomelli¹, Chiara Carollo¹, Michel Chevallard³, Bruno Lucchino³, Mariaeva Romano³, Andrea Locatelli³, Donatella Ventura³, Giovanna Randisi³, Giuliana La Paglia³, Alessandra Mutti³, Alessandro Invernizzi², Stefano De Angelis², Giovanni Staurenghi², Antonio Brucato⁴, Enrico Tombetti⁴. | ¹Dipartimento di Medicina Interna, ASST Fatebenefratelli-Sacco, Università degli studi di Milano, Milano, Italy; ²U.O. Oftalmologia, ASST Fatebenefratelli-Sacco, Università degli studi di Milano, Milano, Italy; ³U.O. Reumatologia, ASST Fatebenefratelli-Sacco, Università degli studi di Milano, Milano, Italy; ⁴Dipartimento di scienze cliniche e biomediche, ASST Fatebenefratelli-Sacco, Università degli studi di Milano, Milano, Italy.

Società Italiana di Reumatologia

DOI https://doi.org/10.4081/reumatismo.2025.2098
- 373 abstract views
PO:37:266 | Long-term manifestation of graft-versus-host disease presenting as a vasculitic-like syndrome: a rare case report

Camilla Mazzanti¹, Gianluca Santoboni¹, Claudio Angrisani¹, Massimiliano De Simone¹, Giuliana Marciani¹, Alessandra Fiorentini¹ | ¹Ospedale Santa Rosa Viterbo, Italy

Società Italiana di Reumatologia

DOI https://doi.org/10.4081/reumatismo.2025.2391
- 142 abstract views
PO:37:267 | Mimickers of polyarteritis nodosa: a case of segmental arteriolar mediolysis

Filippo Santoro¹, Caterina Vacchi², Giulia Cassone², Maria Grazia Malandra¹, Dilia Giuggioli^1|2 | ¹UOSD Reumatologia, Ospedale San Camillo De Lellis, Rieti; ²UOC Igiene e Sanità Pubblica, ASL Rieti; ³Direzione Sanitaria, ASL Rieti, Italy

Società Italiana di Reumatologia

DOI https://doi.org/10.4081/reumatismo.2025.2221
- 381 abstract views
PO:37:268 | Antineutrophil cytoplasmic antibodies-associated vasculitis mimicking giant cell arteritis: a diagnostic dilemma

Bruno Biasi¹, Elena Vanni¹, Marco De Pinto², Giulia Cassone², Dilia Giuggioli^1|2. | ¹Rheumatology Unit, School of Medicine, University of Modena and Reggio Emilia, Modena, Modena, Italy; ²Rheumatology Unit, Azienda Ospedaliera-Universitaria Policlinico di Modena, Modena, Italy, Modena, Italy.

Società Italiana di Reumatologia

DOI https://doi.org/10.4081/reumatismo.2025.2099
- 335 abstract views
PO:37:269 | Intensive therapeutic plasma exchange in life-threatening ANCA-associated vasculitis

Davide Bertelle, Riccardo Bixio, Francesco Pollastri, Maurizio Rossini, Angelo Fassio, Alessandro Giollo | Unità di Reumatologia, Dipartimento di Medicina Clinica e Sperimentale, Università di Pisa

Società Italiana di Reumatologia

DOI https://doi.org/10.4081/reumatismo.2025.2222
- 340 abstract views
PO:37:270 | Efficacy of iloprost as a therapy for skin ulcers in cryofibrinogenemia and cryoglobulinemia: a complex case in a fragile patient

Luca Keller Sarmiento¹, Amelia Spinella², Marco De Pinto², Giorgia Roveta¹, Dilia Giuggioli^1|2. | ¹Università degli Studi di Modena e Reggio Emilia, Modena, Italy; ²Unità di Reumatologia del Policlinico di Modena, Modena, Italy.

Società Italiana di Reumatologia

DOI https://doi.org/10.4081/reumatismo.2025.2100
- 321 abstract views
PO:38:278 | Cognitive behavioural therapy vs. physical therapy for chronic primary low back pain: a systematic review with meta-analysis of randomised controlled trials

Luca Castioni¹, Stefano Salvioli² | ¹Università degli studi di Ferrara; ²Scuola di fisioterapia Claudiana, Bolzano, Italy

Società Italiana di Reumatologia

DOI https://doi.org/10.4081/reumatismo.2025.2223
- 368 abstract views
PO:38:280 | Accuracy of generative artificial intelligence in risk of bias assessment using RoB 2.0 tool and extracting data in exercise therapy for chronic low back pain randomised controlled trials

Luca Carrer¹, Marco Pozzati², Dario Taborelli¹, Niccolò Maschi¹, Tiziano Innocenti^1|3, Stefano Salvioli¹ | ¹DINOGMI, Università di Genova, Savona; ²Dipartimento di Neuroscienze e Riabilitazione, Università di Ferrara; ³GIMBE Foundation, Bologna, Italy

Società Italiana di Reumatologia

DOI https://doi.org/10.4081/reumatismo.2025.2224
- 374 abstract views
PO:38:281 | Therapeutic exercise in temporomandibular disorders: a scoping review of the literature

Federico Amateis1, Gabriele Aimini1, Paolo Mastromarchi1, Lorenzo Lo Russo1, Marco Chiodini1, Roberta Giova Bazzacchi1, Noemi Corbetta1, Stefano Salvioli1. | 1Department of Neurosciences, Rehabilitation, Opthalmology, Genetics, Maternal and Child Health, University of Genoa Italy; 3Scuola Universitaria per la Svizzera Italiana, DEASS Manno Switzerland; 6Department of Maxillo-Facial Surgery, Santi Paolo e Carlo Hospital, University of Milan Italy; 7Department of Neurosciences, Rehabilitation, Opthalmology , Genetics, Maternal and Child Health, University of Genoa Italy; 8Department of Neurosciences, Rehabilitation, Opthalmology , Genetics, Maternal and Child Health, University of Genoa Italy. 

Società Italiana di Reumatologia

DOI https://doi.org/10.4081/reumatismo.2025.2225
- 332 abstract views
PO:38:283 | Accuracy of chatgpt 4 omni in providing clinical recommendations in musculoskeletal care: a valuable support for clinicians and patients?

Dario Taborelli¹, Silvia Negro¹, Federico Padovani², Tiziano Innocenti^1|3, Stefano Salvioli¹ | ¹DINOGMI, Università di Genova, Savona; ²Dipartimento di Neuroscienze e Riabilitazione, Università di Ferrara; ³GIMBE Foundation, Bologna, Italy

Società Italiana di Reumatologia

DOI https://doi.org/10.4081/reumatismo.2025.2226
- 342 abstract views
PO:38:285 | Cross-sectional analysis: interpretation of nonstatistically significant results in randomised controlled clinical trials in rehabilitation

Caterina Mugnai¹, Luca Falsiroli Maistrello^2|3|4, Giacomo Fiacca³, Michele Perrucchini³, Noemi Corbetta³, Federico Amateis³, Stefano Salvioli³ | ¹University of Ferrara; ²ULSS 9 Scaligera, Department of Physical Medicine and Rehabilitation, G. Fracastoro Hospital, San Bonifacio ^VR; ³Department of Neurosciences, Rehabilitation, Ophthalmology, Genetics, Maternal and Child Health, University of Genoa; ⁴School of Physiotherapy, Department of Neuroscience, Biomedicine and Movement, University of Verona, Italy

Società Italiana di Reumatologia

DOI https://doi.org/10.4081/reumatismo.2025.2227
- 270 abstract views
S02:5 | Combined anti-IL-5/IL-5r and dupilumab therapy in eosinophilic granulomatosis with polyangiitis: a European retrospective study

Miriam Guerini¹, Pavel Novikov², Roberto Padoan³, Georgina Espigol Frigolé⁴, Jan Willem Cohen Tervaert⁵, Vincent Grobost⁶, Laurent Guilleminault⁷, Jan Walter Schroeder⁸, Bernhard Hellmich⁹, Joana Martins Martinho¹⁰, Camillo Ribi¹¹, Matthieu Groh¹², Benjamin Terrier¹³. | ¹IRCCS Policlinico S. Matteo, University of Pavia, Pavia, Italy; ²Sechenov University, Moscow, Russia; ³University of Padova, Padova, Italy; ⁴Hospital Clinic, University of Barcelona, Barcelona, Spain; ⁵University of Alberta, Edmonton, Canada; ⁶CHU Estaing Clermont-Ferrand France; ⁷Toulouse University Toulouse France; ⁸ASST Grande Ospedale Metropolitano Niguarda, Milano, Italy; ⁹Medius Kliniken Kirchheim-Teck Germany; ¹⁰ULS Santa Maria, Lisbon, Portugal; ¹¹Centre Hospitalier Universitaire Vaudois, Lausanne, Switzerland; ¹²Hopital Foch, Suresnes, France; ¹³Service de Medecine interne, Hopital Cochin, AP-HP, Paris, France.

Società Italiana di Reumatologia

DOI https://doi.org/10.4081/reumatismo.2025.2101
- 406 abstract views
S02:6 | Monocyte-Driven Inflammation and Inflammasome Activation in ANCA-Positive EGPA: Evidence of Persistent Immune Activation During Remission

Chiara Baggio¹, Luca Iorio¹, Carlotta Boscaro^2|3, Federica Davanzo¹, Marta Tonello¹, Mattia Albiero⁴, Andrea Doria¹, Paolo Sfriso¹, Roberto Padoan¹, Francesca Oliviero¹ | ¹Rheumatology Unit, Department of Medicine, University of Padova, Italy; ²Department of Medicine, University of Padova, Italy; ³Veneto Institute of Molecular Medicine, Laboratory of Experimental Diabetology, Italy; ⁴Department of Surgery, Oncology, and Gastroenterology, University of Padova, Italy

Società Italiana di Reumatologia

DOI https://doi.org/10.4081/reumatismo.2025.2392
- 106 abstract views
S05:5 | Romosozumab in Post-Menopausal Women with Multiple Myeloma, a Prospective 12-Month Study

Giovanni Adami¹, Mariana Diz Lopes¹, Camilla Benini¹, Davide Gatti¹, Ombretta Viapana¹, Elena Marchetti², Martina Tinelli², Maurizio Rossini¹ | ¹UOC Reumatologia, Università degli Studi di Verona Verona, Italy; ²UOC Ematologia, Università degli Studi di Verona Verona, Italy

Società Italiana di Reumatologia

DOI https://doi.org/10.4081/reumatismo.2025.2393
- 137 abstract views
S05:6 | Prevalence of osteoporosis and bone mineral metabolism disorders in an Italian cohort of patients with microcrystalline arthritis: results from the PREMIA observational study of the Italian Society of Rheumatology

Silvia Grignaschi¹, Sonia Farah², Silvia Balduzzi¹, Bernd Raffeiner³, Carlomaurizio Montecucco⁴, Fausto Salaffi², Enrico Selvi⁵, Annamaria Iagnocco⁶, Fabiola Atzeni⁷, Serena Guiducci⁸, Rosario Foti⁹, Maria Manara¹⁰, Marcello Govoni¹¹, Carlo Selmi¹², Francesca Oliviero¹³, Roberta Ramonda¹³ | ¹ASST Pavia; ²Ospedale Carlo Urbani Jesi Italy; ³Azienda Sanitaria dell'Alto Adige, Bolzano; ⁴IRCCS Fondazione Policlinico San Matte, Pavia; ⁵AOU Senese, Siena; ⁶Ospedale MAuriziano, Torino; ⁷Università di Messina; ⁸AOU Careggi, Firenze; ⁹AOU Policlinico G. Rodolico, Catania; ¹⁰ASST Gaetano Pini-CTO Milano; ¹¹AUSL Ferrara; ¹²Humanitas San Pio X, Milano; ¹³AOU Padova, Italy

Società Italiana di Reumatologia

DOI https://doi.org/10.4081/reumatismo.2025.2228
- 283 abstract views
S07:5 | Ankle ultrasound patterns may in the identification of Löfgren’s syndrome in patients with acute-onset erythema nodosum

Davide Corradini¹, Alberto Floris¹, Andrea Carta², Mattia Congia¹, Elisabetta Chessa¹, Matteo Piga¹, Alberto Cauli¹. | ¹Rheumatology Unit, AOU and University of Cagliari, Cagliari, Italy; ²Department Economics and Business, University of Cagliari, Cagliari, Italy.

Società Italiana di Reumatologia

DOI https://doi.org/10.4081/reumatismo.2025.2102
- 317 abstract views
S13:5 | Association between vasoactive-vasodilating therapy and reduced detection of pulmonary arterial hypertension in systemic sclerosis: evidence from a European Scleroderma Trials and Research study

Nicola Farina¹, Silvia Bellando-Randone¹, Sebastien Sanges², Hilde Jenssen Bjørkekjær³, Lorenzo Tofani⁴, Marie-Elise Truchetet⁵, Vanessa Smith⁶, Andra Balanescu⁷, Christina Bergmann⁸, Yannick Allanore⁹, Philipp Klemm¹⁰, Simona Truglia¹¹, Luca Idolazzi¹², Christopher Denton¹³, Roberta Foti¹⁴, Anna Wojteczek¹⁵, Emmanuel Chatelus¹⁶, Madelon Vonk¹⁷, Serena Guiducci¹, David Launay², Eric Hachulla², Jeska De Vries-Bouwstra¹⁸, Anna-Maria Hoffmann-Vold¹⁹, Oliver Distler²⁰, Marco Matucci-Cerinic¹, Cosimo Bruni¹. | ¹Department of Experimental and Clinical Medicine, Scleroderma Unit, Division of Rheumatology, University of Florence, Az, Firenze, Italy; ²Univ. Lille, Inserm, CHU Lille, Department of Internal Medicine and Clinical Immunology, Reference Center for Rare Autoi, Lille, France; ³Department of Rheumatology, Hospital of Southern Norway, Kristiansand, Norway; ⁴Department of Statistics, Informatics and Applications, University of Florence, Firenze, Italy; ⁵Rheumatology department, CHU de Bordeaux, Bordeaux, France; ⁶University of Ghent, Department of Rheumatology, Gent, Belgium; ⁷Department of Rheumatology, St. Maria Hospital, Carol Davila, University of Medicine and Pharmacy Bucharest Romania; ⁸Department Internal Medicine 3, University Hospital Erlangen, Erlangen, Germany; ⁹Rheumatology Department, Université Paris Cité, Cochin Hospital, Paris, France; ¹⁰Department of Rheumatology and Clinical Immunology Center, JLU Giessen, Campus Kerckhoff Bad Nauheim Germany; ¹¹Reumatologia, Azienda Ospedaliero-Universitaria Policlinico Umberto I, Roma, Italy; ¹²Section of Rheumatology, Department of Medicine, University of Verona, Verona, Italy; ¹³Centre for Rheumatology, Royal Free London and University College London Medical School, London, United Kingdom; ¹⁴Division of Rheumatology, A.O.U. Policlinico-San Marco, Catania, Italy; ¹⁵Department of Rheumatology, Clinical Immunology, Geriatrics and Internal Medicine, Medical University of Gdansk, Univers Gdansk Poland; ¹⁶Department of Rheumatology, University Hospital Strasbourg Strasbourg France; ¹⁷Department of rheumatology, Radboud University Nijmegen Medical Center Nijmegen The Netherlands; ¹⁸Department of Rheumatology, Leiden University Medical Center Leiden The Netherlands; ¹⁹Department of Rheumatology, Oslo University Hospital, Oslo, Norway; ²⁰Department of Rheumatology, University Hospital Zurich, University of Zurich, Zurich, Switzerland.

Società Italiana di Reumatologia

DOI https://doi.org/10.4081/reumatismo.2025.2103
- 269 abstract views
S13:6 | Investigating the intricate interplay between pulmonary functionality and advanced microangiopathy in very early diagnosis of systemic sclerosis

Eugenio Capparelli¹, Eleonora Zaccara¹, Daniela Bompane¹, Elisabetta Ricchiuto², Giorgio Bonardi², Laura Castelnovo¹, Antonio Tamburello¹, Antonino Mazzone³, Paola Faggioli¹. | ¹Rheumatology Unit; ²Pneumology Unit; ³Internal Medicine Unit, ASST Ovest Milanese, Legnano, Italy.

Società Italiana di Reumatologia

DOI https://doi.org/10.4081/reumatismo.2025.2104
- 278 abstract views
S14:5 | Erosive hand osteoarthritis: premenopausal onset and more severe disease progression

Marta Favero¹, Giacomo Cozzi¹, Clarissa Benvoluti¹, Laura Scagnellato¹, Gianluca Poncina¹, Stefano Rizzetto¹, Mariagrazia Lorenzin¹, Roberta Ramonda¹ | ¹UOC di Reumatologia, Dipartimento di Medicina-DIMED, Università di Padova, Italy

Società Italiana di Reumatologia

DOI https://doi.org/10.4081/reumatismo.2025.2229
- 404 abstract views