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PO:19:286 | Genetic testing reveals an unexpected case of mevalonate kinase deficiency in a 37-year-old patient with AA renal amyloidosis and good response to colchicine Francesca Crisafulli1, Paolo Airò2, Federica Mescia3, Gianmarco Lugli3, Gianfranco Savoldi4, Claudia Izzi3|5, Federico Alberici3, Marco Cattalini6, Franco Franceschini1, Micol Frassi2. | 1Rheumatology and Clinical Immunology Unit, ASST Spedali Civili and University of Brescia, Brescia, Italy; 2Rheumatology and Clinical Immunology Unit, ASST Spedali Civili of Brescia, Brescia, Italy; 3U.O Nefrologia, ASST Spedali Civili di Brescia e Università degli Studi di Brescia, Brescia, Italy; 4Medical genetics Laboratory, Laboratory Department ASST Spedali Civili di Brescia, Brescia, Italy; 5Struttura Complessa di Genetica Clinica, ASST Spedali Civili di Brescia, Brescia, Italy; 6Pediatrics Clinic, University of Brescia and ASST Spedali Civili of Brescia, Brescia, Italy.
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PO:31:174 | Increased frequency of anti-RNA polymerase 3 antibodies in patients with systemic sclerosis and silicone breast implants: a multicentre study from the international European Scleroderma Trials and Research cohort Maria Grazia Lazzaroni1, Yolanda Braun-Moscovici2, Elda Piovani1, Claudia Barison1, Liala Moschetti1, Veronica Batani3, Corrado Campochiaro3, Michal Tomcik4, Francesca Motta5, Maria De Santis5, Petros P. Sfikaki6, Masataka Kuwana7, Brigitte Granel8, Roberta Foti9, Virginia Berlingiero10, Joana Caetano11, Yannick Allanore12, Alexandra Balbir-Gurman2, Marco Matucci Cerinic3, Franco Franceschini1, Paolo Airò1. | 1ASST Spedali Civili of Brescia, University of Brescia, Brescia, Italy; 2Rambam Health Care Campus, Rappaport Faculty of Medicine, Technion-Israeli Institute of Tecnology, Haifa, Israel; 3Vita-Salute San Raffaele University, San Raffaele Hospital, Milano, Italy; 4Institute of Rheumatology, Praga, Czech Republic; 5IRCCS Humanitas Research Hospital; Humanitas University, Milano, Italy; 6Joint Rheumatology Program, Medical School, National Kapodistrian University of Athens Atene GREECE; 7Nippon Medical School Hospital Tokyo Japan; 8Hôpital Nord de Marseille; Aix-Marseille Université Marsiglia France; 9AOU Policlinico G. Rodolico San Marco, Catania, Italy; 10Azienda Ospedaliera Universitaria Senese, Siena, Italy; 11Fernando Fonseca Hospital, Amadora, Portugal; 12Université Paris Cité, Cochin Hospital, Parigi, France.
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PO:22:032 | Beyond the joints: a rare case of subcorneal pustular dermatosis in Rheumatoid Arthritis Sara Casella1|2, Carlo Smirne1|2, Roberta Zaira Pedrazzoli3, Mattia Perazzi1|3, Edoardo Cammarata4, Francesca Zottarelli4, Paola Savoia5, Renzo Boldorini6, Mario Pirisi1|2, Pier Paolo Sainaghi1|3 | 1Dipartimento di Medicina Traslazionale, Università del Piemonte Orientale Novara, Italy; 2Unità di Medicina Interna, Azienda Ospedaliera Maggiore della Carità Novara, Italy; 3Unità di Medicina Interna e Reumatologia, Azienda Ospedaliera Maggiore della Carità Novara, Italy; 4Unità di Dermatologia, Azienda Ospedaliera Maggiore della Carità Novara, Italy; 5Dipartimento di Scienze della salute, Università del Piemonte Orientale Novara, Italy; 6Unità di Anatomia Patologica, Azienda Ospedaliera Maggiore della Carità Novara, Italy
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PO:30:157 | Radiographic assessment of measurable osteoarticular damage in juvenile idiopathic arthritis (JIA) patients transitioning to adult care Serena Pastore4, Marta Klanmjsceck3, Andrea Guiotto1, Laura De Nardi5|6, Alessia Pin4, Lorenzo Cereser1|2, Andrea Taddio3|4, Luisa Occhipinti1, Luca Quartuccio1|2, Alberto Tommasini3|4, Alen Zabotti2 | 1Università degli Studi di Udine Udine, Italy; 2Ospedale Santa Maria della Misericordia Udine, Italy; 3Università degli Studi di Trieste Trieste, Italy; 4IRCCS Materno Infantile Burlo Garofolo Trieste, Italy; 5Università Tor Vergata Roma, Italy; 6Ospedale Pediatrico Bambino Gesù Roma, Italy
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PO:31:165 | Prevalence and incidence of skin telangectasia and their association with clinical features: analysis of the European Scleroderma Trials and Research cohort Gemma Lepri1, Lorenzo Tofani2, Silvia Bellando Randone1, Veronica Batani3, Paolo Airò4, Patricia Carreira5, Joerg Henes6, Alexandra Balbir Gurman7, Florenzo Iannone8, Antonella Marcoccia9, Luc Mouthon10, Branimir Anic11, Carolina De Souza Müller12, Armine Haroyan13, Ana Cristina Cordeiro14, Serena Guiducci And Eustar Coll1. | 1University of Florence, Dept of Experimental and Clinical Medicine, AOU Careggi, Division of Rheumatology Florence Italy; 2University of Florence, Dept of Statistics, Informatics, Applications, Florence, Italy; 3Unit of Immunology, Rheumatology, Allergy and Rare Diseases UnIRAR, IRCCS San Raffaele, Milano, Italy; 4Scleroderma Unit, UOC Rheumatology and Clinical Immunology, ASST Spedali Civili, Brescia, Italy; 5Dept of Rheumatology, 12 de Octubre University Hospital, Madrid, Spain; 6Centre for Interdisciplinary Rheumatology, Immunology and autoimmune diseases INDIRA, University Hospital Tuebingen, Tuebingen, Germany; 7Rheumatology Institute, Rambam Health Care Campus Haifa Israel; 8Dept of Precision and Regenerative Medicine and Ionian Area, University of Bari, Bari, Italy; 9Interdisciplinary Reference Center for Systemic Sclerosis CRIIS Sandro Pertini Hospital, Rome, Italy; 10Dept of Internal Medicine, Cochin Hospital, Paris Cité University, Paris, France; 11Div Clinical Immunology and Rheumatology, Dept Internal Medicine, School of Medicine, University Hospital Center Zagreb, Zagreb, Croatia; 12Rheumatology Division, Hospital de Clínicas da Universidade Federal do Parana, Curitiba, Brazil; 13Dept of Rheumatology, Yerevan State Medical University of Armenia, Yerevan, Armenia; 14Servico Reumatologia Hospital Garcia de Orta Almada, Almada, Portugal.
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PO:16:232 | Belimumab step-down dose spacing in patients with systemic lupus erythematosus in persistent clinical remission: experience from a multicentric cohort Alice Bartoletti1, Laura Giudice1, Lorenza Maria Argolini1|2, Giuseppe Alvise Ramirez3, Luca Moroni3, Tommaso Schioppo4, Chiara Bellocchi5|6, Annalaura Fasiello6, Lorenzo Beretta6, Lorenzo Dagna3, Roberto Caporali1, Maria Gerosa1. | 1UO Clinica Reumatologica, ASST Gaetano Pini CTO, Milano, Italy; 2UOC Medicina fisica e riabilitazione specialistica, ASST Gaetano Pini CTO, Milano, Italy; 3Unit of Immunology, Rheumatology, Allergy and Rare Diseases, IRCCS San Raffaele Hospital, Vita-Salute San Raffa Milano Italy; 4Medicina Generale II, Servizio di Reumatologia, Ospedale San Paolo, ASST Santi Paolo Carlo, Milano, Italy; 5Department of Clinical Sciences and Community Health, University of Milan, Dipartimeto di Eccellenza 2023-2027, Milano, Italy; 6Referral Centre for Systemic Autoimmune DIseases, Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico, Milano, Italy
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PO:14:199 | Preliminary data of a multicentric study on safety and efficacy of assisted reproductive techniques in pregnant women with systemic autoimmune diseases Valentina Canti1, Maria Bernadette Cilona1, Giuditta Gorgone1, Federica Pasi1, Antonia Calligaro2, Francesca Ruffilli3, Francesca Crisafulli6, Maria Tonello2, Eleonora Giacobbe4, Alba Chiara Pozzi6, Maria Chiara Gerardi4, Melissa Padovan3, Emanuele Bizzi5, Enrico Papaleo1, Beatrice Maranini3, Marcello Govoni3, Massimiliano Epis4, Angela Tincani6, Andrea Doria2, Patrizia Rovere Querini1 | 1IRCCS Ospedale San Raffaele and VitaSalute San Raffaele Milano, Italy; 2Rheumatology Unit, Departement of Medicine, University Hospital of Padua Padova, Italy; 3Rheumatology Unit, Azienda Ospedaliero Universitaria S. Anna Ferrara, Department of Medical Sciences, University of Fe Ferrara, Italy; 4ASST Grande Ospedale Metropolitano Niguarda Milano, Italy; 5Internal Medicine, Fatebenefratelli Hospital Milano, Italy; 6Rheumatology and Immunology Unit, ASST Spedali Civili Brescia e Università degli Studi di Brescia, Italy
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PO:19:284 | Use of anakinra during pregnancy and breastfeeding in women with recurrent pericarditis: a case series Lucia Trotta1, Marco Quartarone1, Francesco Cavaleri1, Ruggiero Mascolo1, Massimo Imazio3, Vartan Mardygan2, Andreja Cerne Cercek4, Anne-Marie Claveau2, Ludovico Luca Sicignano5, Massimo Pancrazi1, Alida Caforio6, Andrea Silvio Giordani6, Serdal Ugurlu7, Alessandro Andreis8, Valentino Collini3, Enrico Tombetti9, Antonio Brucato9 | 1Department of Internal Medicine, ASST Fatebenefratelli-Sacco, Milan, Italy; 2Division of Cardiology, Department of Medicine, Jewish General Hospital, Montréal, Québec, Canada; 3Cardiology, Cardiothoracic Department, University Hospital Santa Maria della Misericordia, Udine, Italy; 4Department of Cardiology, University Medical Centre Ljubljana, Ljubljana, Slovenia; 5Fondazione Policlinico Universitario Agostino Gemelli IRCCS, Rome, Italy; 6Division of Cardiology, Centro Gallucci, University of Padova-Policlinico, Padova, Italy; 7Division of Rheumatology, Department of Internal Medicine, Istanbul University-Cerrahpasa, Istanbul, Turkey; 8University Cardiology, A.O.U. Città della Salute e della Scienza di Torino, Torino, Italy; 9Department of Biomedical and Clinical Sciences, Fatebenefratelli Hospital, University of Milan, Milan, Italy
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PO:10:141 | A Case Study: Navigating the VEXAS Syndrome Mimickers Erika Montabone1, Richard Borrelli1, Nicolò Rashidy1, Fabiana Giannoccaro2, Giuseppe Guida2, Federico Itri3, Renato Carignola4, Simone Negrini1, Stefania Nicola1, Luca Lo Sardo1, Iuliana Badiu1, Federica Corradi1, Ambra Bonvicino5, Maurizio Balbi6, Luisa Brussino1 | 1SCDU Immunologia e Allergologia, AO Mauriziano, Dipartimento di Scienze Mediche, Università degli Studi di Torino Torino, Italy; 2SSD Asma grave, malattie rare del polmone e fisiopatologia respiratoria, AOU San Luigi Gonzaga Orbassano, Italy; 3SCDU Medicina Interna ad indirizzo Ematologico, AOU San Luigi Gonzaga Orbassano, Italy; 4SCDU Medicina Interna, Scleroderma Unit, AOU San Luigi Gonzaga Orbassano, Italy; 5SCDU Dermatologia, Città della Salute e della Scienza di Torino Torino, Italy; 6SCDU Radiodiagnostica, AOU San Luigi Gonzaga, Dipartimento di Oncologia Orbassano, Italy
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S13:5 | Association between vasoactive-vasodilating therapy and reduced detection of pulmonary arterial hypertension in systemic sclerosis: evidence from a European Scleroderma Trials and Research study Nicola Farina1, Silvia Bellando-Randone1, Sebastien Sanges2, Hilde Jenssen Bjørkekjær3, Lorenzo Tofani4, Marie-Elise Truchetet5, Vanessa Smith6, Andra Balanescu7, Christina Bergmann8, Yannick Allanore9, Philipp Klemm10, Simona Truglia11, Luca Idolazzi12, Christopher Denton13, Roberta Foti14, Anna Wojteczek15, Emmanuel Chatelus16, Madelon Vonk17, Serena Guiducci1, David Launay2, Eric Hachulla2, Jeska De Vries-Bouwstra18, Anna-Maria Hoffmann-Vold19, Oliver Distler20, Marco Matucci-Cerinic1, Cosimo Bruni1. | 1Department of Experimental and Clinical Medicine, Scleroderma Unit, Division of Rheumatology, University of Florence, Az, Firenze, Italy; 2Univ. Lille, Inserm, CHU Lille, Department of Internal Medicine and Clinical Immunology, Reference Center for Rare Autoi, Lille, France; 3Department of Rheumatology, Hospital of Southern Norway, Kristiansand, Norway; 4Department of Statistics, Informatics and Applications, University of Florence, Firenze, Italy; 5Rheumatology department, CHU de Bordeaux, Bordeaux, France; 6University of Ghent, Department of Rheumatology, Gent, Belgium; 7Department of Rheumatology, St. Maria Hospital, Carol Davila, University of Medicine and Pharmacy Bucharest Romania; 8Department Internal Medicine 3, University Hospital Erlangen, Erlangen, Germany; 9Rheumatology Department, Université Paris Cité, Cochin Hospital, Paris, France; 10Department of Rheumatology and Clinical Immunology Center, JLU Giessen, Campus Kerckhoff Bad Nauheim Germany; 11Reumatologia, Azienda Ospedaliero-Universitaria Policlinico Umberto I, Roma, Italy; 12Section of Rheumatology, Department of Medicine, University of Verona, Verona, Italy; 13Centre for Rheumatology, Royal Free London and University College London Medical School, London, United Kingdom; 14Division of Rheumatology, A.O.U. Policlinico-San Marco, Catania, Italy; 15Department of Rheumatology, Clinical Immunology, Geriatrics and Internal Medicine, Medical University of Gdansk, Univers Gdansk Poland; 16Department of Rheumatology, University Hospital Strasbourg Strasbourg France; 17Department of rheumatology, Radboud University Nijmegen Medical Center Nijmegen The Netherlands; 18Department of Rheumatology, Leiden University Medical Center Leiden The Netherlands; 19Department of Rheumatology, Oslo University Hospital, Oslo, Norway; 20Department of Rheumatology, University Hospital Zurich, University of Zurich, Zurich, Switzerland.
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PO:35:222 | Distinctive Features of Localized Vasculitis of the Gastrointestinal Tract Compared to Takayasu Arteritis: Insights from a Multicenter Cohort Study Vittorio Dibenedetto1|2|3, Alessandro Tomelleri1|2, Corrado Campochiaro1|2, Elena Baldissera1|2, Luca Moroni1|2, Padoan Roberto4, Marco Matucci-Cerinic1|2|3, Lorenzo Dagna1|2|3 | 1Unit of Immunology, Rheumatology, Allergy and Rare Diseases UNIRAR, IRCCS San Raffaele Hospital Milan, Italy; 2Inflammation, Fibrosis and Ageing Intitiative INFLAGE, IRCCS San Raffaele Hospital Milan, Italy; 3Vita-Salute San Raffaele University, Milan, Italy Milan, Italy; 4University Hospital of Padova, Department of Internal Medicine and Rheumatology Padova, Italy
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PO:01:008 | Active sacroiliitis at magnetic resonance enterography increases the risk of axial spondyloarthritis in Crohn’s disease patients, while greater age and disease duration are protective factors: a monocentric retrospective cohort study Gabriele Amati1, Gilda Sandri1|2, Giovanni Ciancio2, Benedetta Bongiovanni1|2, Martina Orlandi1|2, Ottavio Secchi1|2, Davide Vaccari3, Annarita Pecchi4, Angela Bertani5, Maddalena Pecchini5, Pietro Torricelli4, Antonio Colecchia5, Dilia Giuggioli1|2. | 1Struttura Complessa di Reumatologia, Azienda Ospedaliero-Universitaria Policlinico di Modena, Modena, Italy; 2Cattedra di Reumatologia, Università degli studi di Modena e Reggio Emilia, Modena, Italy; 3Unità Operativa di Radiologia, Ospedale di Pavullo, AUSL di Modena, Modena, Italy; 4Struttura Complessa di Radiologia, Azienda Ospedaliero-Universitaria Policlinico di Modena, Modena, Italy; 5Struttura Complessa di Gastroenterologia, Azienda Ospedaliero-Universitaria Policlinico di Modena, Modena, Italy.
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PO:32:185 | Deep-learning analysis of high-resolution computed tomography images predicts progression and mortality in systemic sclerosis related interstitial lung disease Valentina Boni1, Rosa D'Abronzo2, Piergiacomo Cerasuolo1, Lucio Calandriello2, Giuseppe Cicchetti2, Gerlando Natalello1, Bruno Iovene5, Francesco Varone5, Giacomo Sgalla5, Luca Richeldi5, Anna Rita Larici2|4, Maria Antonietta D'Agostino1|3, Silvia Laura Bosello1|3, Enrico De Lorenzis1. | 1Division of Rheumatology and Clinical Immunology Catholic Univeristy of the Sacred Heart, Rome, Italy; 2Department of Diagnostic Imaging, Oncological Radiotherapy and Hematology, Diagnostic Imaging Area, Catholic University, Rome, Italy; 3Department of Geriatric and Orthopaedic Sciences, Catholic Univeristy of the Sacred Heart, Rome, Italy; 4Department of Radiological and Hematological Sciences, Section of Radiology, Catholic Univeristy of the Sacred Heart, Rome, Italy; 5Division of Pulmonary Medicine, Catholic University of the Sacred Heart, Roma, Italy.
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PO:32:176 | Outcomes of upfront combination vs monotherapy with rituximab or mycophenolate mofetil for systemic sclerosis interstitial lung disease: results from a European Scleroderma Trials and Research cohort study Devis Benfaremo1, Corrado Campochiaro2, Gábor Kumánovics3, Christina Bergmann4, Elisabetta Zanatta5, David Launay6, Serena Guiducci7, Mickael Martin8, Carolina De Souza Müller9, Carlomaurizio Montecucco10, Luc Mouthon11, Gabriella Szucs12, Kastriot Kastrati13, Marie-Elise Truchetet14, Madelon Vonk15, Francesco Del Galdo16, Marco Matucci-Cerinic2, Gianluca Moroncini1, Yannick Allanore17. | 1Department of Clinical and Molecular Sciences, Marche Polytechnic University, Marche University Hospital, Ancona, Italy; 2Vita-Salute San Raffaele University, San Raffaele Hospital, Milano, Italy; 3University of Pécs, Department Of Rheumatology And Immunology, Pécs, Hungary; 4University Hospital Erlangen, Department Internal Medicine 3, Erlangen, Germany; 5Padova University Hospital, Rheumatology Unit, Padova, Italy; 6Univ. Lille, Inserm, CHU Lille, Department of Internal Medicine and Clinical Immunology, Lille, France; 7University of Florence, Azienda Ospedaliera Universitaria Careggi, Firenze, Italy; 8Poitiers University Hospital, Department of Internal Medicine Poitiers France; 9Hospital de Clinicas da Universidade Federal do Parana Curitiba Brazil; 10Università di Pavia e IRCCS Fondazione Policlinico S. Matteo, Pavia, Italy; 11Hôpital Cochin, Department of Internal Medicine, Paris, France; 12University of Debrecen, Faculty of Medicine, Department of Rheumatology, Debrecen, Hungary; 13Medical University of Vienna, Department of Medicine III, Division of Rheumatology, Vienna, Austria; 14CHU de Bordeaux, Rheumatology department, Bordeaux, France; 15Radboudumc, Department of Rheumatology Nijmegen The Netherlands; 16Leeds Raynauds and Scleroderma Program, NIHR Biomedical Research Centre, Leeds, United Kingdom; 17Université Paris Cité, Cochin Hospital, Rheumatology Department, Paris, France.
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PO:35:228 | Polymyalgia rheumatica and giant cell arteritis induced by immune checkpoint inhibitors for cancer treatment: a systematic review and meta-analysis highlighting differences from the idiopathic forms Elvis Hysa1, Andrea Casabella2, Emanuele Gotelli1, Rosanna Campitiello1, Carlo Genova3, Enrica Teresa Tanda4, Carmen Pizzorni1, Alberto Sulli1, Vanessa Smith5, Marco Amedeo Cimmino6, Sabrina Paolino1, Maurizio Cutolo1. | 1Laboratory of Experimental Rheumatology and Academic Division of Clinical Rheumatology, Department of Internal Medicine, Genova, Italy; 2IRCCS Ospedale Policlinico San Martino, Genova, Italy; 3Academic Oncology Unit; IRCCS Ospedale Policlinico San Martino, Genova, Italy; 4UOC Medical Oncology Clinic 2, Department of Internal Medicine, University of Genova, Genova, Italy; 5Department of Internal Medicine, Ghent University, Department of Rheumatology, Ghent University Hospital, Ghent, Belgium; 6Rheumatology Outpatient Clinic, Villa Ravenna Chiavari Italy.
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PO:16:227 | Anifrolumab for Systemic Lupus Erythematosus: Preliminary Safety and Efficacy Findings from the Italian Experience Paola Bizioli1|2, Chiara Orlandi1|2, Claudia Barison1|2, Cesare Tomasi3, Alessia Caproli1, Silvia Piantoni1|2, Simona Signorini4, Emirena Garrafa4, Cecilia Nalli1, Micol Frassi1, Ilaria Cavazzana1|2, Micaela Fredi1|2, Franco Franceschini1|2 | 1Rheumatology and Clinical Immunology Unit - ERN ReCONNET, ASST Spedali Civili of Brescia, Italy; 2Department of Clinical and Experimental Sciences, University of Brescia, Italy; 3Department of Clinical and Experimental Sciences, University of Brescia, Italy; 4Laboratory of Clinical Chemistry, Department of Molecular and Translational Medicine, University of Brescia, Italy
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PO:35:234 | Sustained Vasculitis Quiescence and CS Reduction with Mepolizumab 100 mg Francesca Mascia1, Angelo Fassio2, Marco Zurlo1, Davide Chesini3, Francesco Pollastri2, Giovanni Adami2, Davide Gatti4, Maurizio Rossini4, Matteo Maule5, Gianentrico Senna1, Marco Caminati1 | 1University of Verona - Allergology and Clinical Immunology Verona, Italy; 2Policlinico G. B. Rossi - Rheumatology Verona, Italy; 3University of Verona - Faculty of Medicine and Surgery Verona, Italy; 4University of Verona - Rheumatology Verona, Italy; 5Policlinico G. B. Rossi - Allergology and Clinical Immunology Verona, Italy
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CO:11:3 | Belimumab for lupus nephritis patients with poor kidney function: a post-hoc analysis of the bliss-ln trial Giacomo Emmi1|2, Ersilia Lucenteforte3, Giorgio Limoncella3, Emanuele Chiara1|2, Marta Calatroni4|5, Gabriella Moroni4|5 | 1Clinical Medicine and Rheumatology Unit, Cattinara University Hospital, Trieste, Italy; 2Department of Medical, Surgical and Health Sciences, University of Trieste, Trieste, Italy; 3Department of Statistics, Informatics and Applications Giuseppe Parenti, University of Florence, Florence, Italy; 4Department of Biomedical Sciences, Humanitas University, Pieve Emanuele, Milan, Italy; 5Nephrology and Dialysis Division, IRCCS Humanitas Research Hospital, Milan, Italy
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PO:33:193 | Self-reported oropharyngeal dysphagia and swallowing-related quality of life in people with systemic sclerosis: preliminary results of a cross-sectional study Nikla Pacenti1, Devis Benfaremo2, Federica Lucia Galli2, Andrea Colangelo3, Gianluca Moroncini2 | 1Internal Medicine Residency Program, Marche Polytechnic University Ancona, Italy; 2Department of Clinical and Molecular Sciences, Marche Polytechnic University Ancona, Italy; 3Medical student, Marche Polytechnic University Ancona, Italy
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PO:26:096 | From free text to diagnosis: a Natural Language Processing approach for identifying rheumatoid and psoriatic arthritis in the Emergency Department Antonio Tonutti1|2, Pierandrea Morandini3, Cosimo Faeti3, Nicoletta Luciano1|2, Saverio D'Amico3, Antonio Voza1|4, Victor Savevski3, Carlo Selmi1|2 | 1Department of Biomedical Sciences, Humanitas University Pieve Emanuele, Milan, Italy; 2Rheumatology and Clinical Immunology, IRCCS Humanitas Research Hospital Rozzano, Milan, Italy; 3Artificial Intelligence Unit, IRCCS Humanitas Research Hospital Rozzano, Milan, Italy; 4Emergency Department, IRCCS Humanitas Research Hospital Rozzano, Milan, Italy
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CO:12:5 | Aortic inflammation and aneurysm risk in giant cell arteritis: a multicenter imaging study Caterina Ricordi1, Chiara Marvisi1, Konstanze V. Guggenberger2, Rudolf A. Werner3, Pamela Mancuso8, Giulia Besutti4, Sebastian E. Serfling5, Roberto Farì4, Matthias Frohlich6, Rexhep Durmo7, Michael Gernert6, Lucia Spaggiari4, Annibale Versari7, Paolo Giorgi Rossi8, Pierpaolo Pattacini4, Marc Schmalzing6, Carlo Salvarani1, Thorsten Bley9, Francesco Muratore1. | 1Rheumatology Unit, AUSL IRCCS di Reggio Emilia and Università di Modena e Reggio Emilia, Italy; 2Department of Diagnostic and Interventional Neuroradiology, University Hospital Wuerzburg, Germany; 3Department of Nuclear Medicine, University of Frankfurt, Germany; 4Department of Radiology, AUSL IRCCS di Reggio Emilia, Italy; 5Department of Nuclear Medicine, University Hospital Wuerzburg, Germany; 6Rheumatology and Clinical Immunology, Department of Internal Medicine II, University Hospital Wuerzburg, Germany; 7Nuclear Medicine Unit, AUSL IRCCS di Reggio Emilia, Italy; 8Epidemiology Unit, AUSL-IRCCS di Reggio Emilia, Italy; 9Department of Diagnostic and Interventional Radiology, University Hospital Wuerzburg, Germany
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PO:07:098 | Reasons for treatment failure and their synovial correlate among patients with difficult-to-treat rheumatoid arthritis Alessandro Giollo1, Mariangela Salvato1, Francesca Frizzera1, Kiren Khalid1, Lorenzo Di Luozzo1, Carlo Garaffoni2, Maria Capita2, Marianna Tamussin2, Giovanni Lanza2, Marny Fedrigo3, Annalisa Angelini3, Roberta Ramonda1, Ettore Silvagni2, Andrea Doria1 | 1UOC Reumatologia Padova, Italy; 2UOC Reumatologia Ferrara, Italy; 3UOC Patologia cardiovascolare Padova, Italy; 4UOC Anatomia Patologica Ferrara, Italy
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PO:27:106 | Role of histology in interstitial lung involvement of rheumatic diseases in real life scenario Francesca Cozzini1|2, Francesco Falco1, Lucia Spaggiari1|3, Alberto Cavazza1, Adele Del Giudice1|2, Lucia Dardani1, Fabio Brandolino1, Emanuele Cocchiara1, Ilaria Chiapparoli1, Luca Magnani4, Gianluigi Bajocchi1, Carlo Salvarani1|2, Andreina Manfredi1|2 | 1IRCCS Arcispedale Santa Maria Nuova Reggio Emilia, Italy; 2Università degli Studi di Modena e Reggio Emilia Modena, Italy; 3AUSL area NORD Montecchio-Guastalla, Italy; 4UOC di Medicina Interna ad Indirizzo Reumatologico, Azienda USL Bologna, Ospedale Maggiore Bologna, Italy
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PO:37:254 | Absence of ciliary artery occlusion does not exclude arteritic anterior ischemic optic neuropathy (A-AION): diagnostic and pathophysiologic implications Ruggiero Mascolo Mascolo1, Stefano Erba2, Alba Xhepa2, Martina Martelli1, Gabriella Marinaro1, Giulia Dieguez1, Giacomo Iacomelli1, Chiara Facoetti1, Michel Chevallard3, Bruno Lucchino3, Mariaeva Romano3, Andrea Locatelli3, Giuliana La Paglia3, Donatella Ventura3, Giovanna Randisi3, Alessandra Mutti3, Alessandro Invernizzi2, Stefano De Angelis2, Giovanni Staurenghi2, Antonio Brucato4, Enrico Tombetti4 | 1Dipartimento di Medicina Interna, ASST Fatebenefratelli-Sacco, Università degli studi di Milano, Italy; 2U.O. Oculistica, ASST Fatebenefratelli-Sacco Milano, Italy; 3U.O. Reumatologia, ASST Fatebenefratelli-Sacco Milano, Italy; 4Dipartimento di Scienze cliniche e biomediche, ASST Fatebenefratelli-Sacco, Università degli studi di Milano, Italy
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PO:36:243 | Drug survival, discontinuation reasons and disease activity in patients with Behçet's disease treated with infliximab - a real-life study Antonello Sulis1, Federica Di Cianni1, Maria Laura Manca2, Rosaria Talarico1, Marta Mosca1. | 1Rheumatology Unit of Pisa, University of Pisa, Pisa, Italy, Pisa, Italy; 2Department of Clinical and Experimental Medicine and Department of Mathematics, University of Pisa, Italy, Pisa, Italy.
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PO:01:001 | Clinical and histopathological features of refractory psoriatic arthritis undergoing ultrasound-guided synovial biopsy: comparison between non-inflammatory and persistent inflammatory profiles Marianna Tamussin1, Carlo Garaffoni1, Maria Capita1, Serena Ceccato1, Giovanni Lanza2, Mariangela Salvato3, Kiren Khalid3, Francesca Frizzera3, Lorenzo Di Luozzo3, Annalisa Angelini4, Roberta Ramonda3, Alessandra Bortoluzzi1, Andrea Doria3, Marcello Govoni1, Alessadro Giollo3, Ettore Silvagni1 | 1Rheumatology Unit, Department of Medical Sciences, University of Ferrara and Azienda Ospedaliero-Universitaria S. Anna Ferrara, Italy; 2Pathology Unit, Department of Translational Medicine, University of Ferrara, Ferrara Ferrara, Italy; 3Rheumatology Unit, Department of Medicine , DIMED, University of Padua Padova, Italy; 4Cardiovascular Pathology, Department of Cardiac, Thoracic, Vascular Sciences and Pulic Health, University of Padua, Padova, Italy
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PO:32:182 | Disease characteristics of anti-centromere positive systemic sclerosis patients and risk factors for organ involvement: data from the EUSTAR cohort Corrado Campochiaro1, Jelena Colic2, Del Papa Nicoletta3, Oliver Distler4, Serena Guiducci5, Florenzo Iannone6, David Launay7, Yair Levy8, Britta Maurer9, Arsene Mekinian10, Predrag Ostojic2, Gabriela Riemekasten11, Petros Sfikakis12, Bojana Stamenkov13, Ulrich Walker14, Marie Elise Truchetet15, Madelon Vonk16, Francesco Del Galdo17, Giacomo De Luca1, Lorenzo Dagna1, Marco Matucci Cerinic1, Yannick Allanore18 | 1IRCCS San Raffaele Hospital; Vita Salute San Raffaele University Milan, Italy; 2University of Belgrade Belgrade, Serbia; 3UOC Reumatologia Clinica, ASST G. Pini CTO Milan, Italy; 4University Hospital Zurich Zurich, Switzerland; 5Department of Rheumatology, University of Florence Florence, Italy; 6Rheumatology Unit Bari, Italy; 7CHU Lille Lille, France; 8Department of Medicine Kfar Saba, Israel; 9Department for BioMedical Research, University of Bern Bern, Switzerland; 10Service de medecine interne Paris, France; 11Department of Rheumatology University of Lubeck Lubeck Germany; 12National and Kapodistrian University of Athens Athens, Greece; 13University School of Medicine, Nis Nis, Serbia; 14University Hospital Basel, Basel Basel, Switzerland; 15Bordeaux Hospital and University Bordeaux, France; 16Radboud University Nijmegen Medical Centre, Nijmegen, The Netherlands; 17Leeds Institute of Rheumatic and Muskuloskeletal Medicine Leeds, United Kingdom; 18Cochin Hospital Paris, France
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PO:16:234 | Differential efficacy of induction treatments for lupus nephritis at onset and relapses: an observational study Giuseppe Alvise Ramirez1|2, Gabriele D Gallina1, Chiara Calabrese1|2, Serena Nannipieri1|2, Marta Calatroni3|4, Francesco Reggiani3|4, Giovanni Benanti1, Enrica Paola Bozzolo1, Raffaele Ceniccola2, Luca Moroni1|2, Marco Matucci-Cerinic1|2, Gabriella Moroni3|4, Lorenzo Dagna1|2 | 1IRCCS San Raffaele Hospital, Unit of Immunology, Rheumatology, Allergy and Rare Diseases Milan, Italy; 2Vita- Salute San Raffaele University Milan, Italy; 3IRCCS Humanitas Research Hospital, Nephrology and Dialysis Division Rozzano, Milan, Italy; 4Humanitas University, Department of Biomedical Sciences Rozzano, Milan, Italy
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PO:38:281 | Therapeutic exercise in temporomandibular disorders: a scoping review of the literature Federico Amateis<sup>1</sup>, Gabriele Aimini<sup>1</sup>, Paolo Mastromarchi<sup>1</sup>, Lorenzo Lo Russo<sup>1</sup>, Marco Chiodini<sup>1</sup>, Roberta Giova Bazzacchi<sup>1</sup>, Noemi Corbetta<sup>1</sup>, Stefano Salvioli<sup>1</sup>. | <i> <sup>1</sup>Department of Neurosciences, Rehabilitation, Opthalmology, Genetics, Maternal and Child Health, University of Genoa Italy; <sup>3</sup>Scuola Universitaria per la Svizzera Italiana, DEASS Manno Switzerland; <sup>6</sup>Department of Maxillo-Facial Surgery, Santi Paolo e Carlo Hospital, University of Milan Italy; <sup>7</sup>Department of Neurosciences, Rehabilitation, Opthalmology , Genetics, Maternal and Child Health, University of Genoa Italy; <sup>8</sup>Department of Neurosciences, Rehabilitation, Opthalmology , Genetics, Maternal and Child Health, University of Genoa Italy. </i>
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PO:25:075 | Cancer occurence in patients with idiopathic inflammatory myopathies: new insights from the analysis of a monocentric cohort Michele Diomedi1, Federico Fattorini1, Simone Barsotti2, Chiara Cardelli1|3, Elenia Laurino4, Alessandra Tripoli4, Linda Carli4, Marta Mosca1|4. | 1Rheumatology Unit, Department of Clinical and Experimental Medicine, University of Pisa, Pisa, Italy; 2Rheumatology, Versilia Hospital, Viareggio, Italy; 3Department of Medical Biotechnologies, University of Siena, Siena, Italy; 4Rheumatology Unit, AOUP, Pisa, Italy.
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S02:6 | Monocyte-Driven Inflammation and Inflammasome Activation in ANCA-Positive EGPA: Evidence of Persistent Immune Activation During Remission Chiara Baggio1, Luca Iorio1, Carlotta Boscaro2|3, Federica Davanzo1, Marta Tonello1, Mattia Albiero4, Andrea Doria1, Paolo Sfriso1, Roberto Padoan1, Francesca Oliviero1 | 1Rheumatology Unit, Department of Medicine, University of Padova, Italy; 2Department of Medicine, University of Padova, Italy; 3Veneto Institute of Molecular Medicine, Laboratory of Experimental Diabetology, Italy; 4Department of Surgery, Oncology, and Gastroenterology, University of Padova, Italy
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PO:31:166 | S'/PAPs ratio in systemic sclerosis: a promising non-invasive index for early detection and prognosis of pulmonary hypertension. A step toward more accurate screening? Marco De Pinto1, Amelia Spinella1, Pierluca Macripò2, Alessia Laneri1, Benedetta Bongiovanni1, Maria Grazia Malandra1, Martina Orlandi1-3, Gianluca Pagnoni2, Arianna Maini2, Rosario Rossi2-4, Clodoveo Ferri1, Francesca Coppi2-3, Dilia Giuggioli1-3. | 1Rheumatology Unit, Azienda Ospedaliero-Universitaria Policlinico di Modena, University of Modena and Reggio Emilia, Modena, Italy; 2Cardiology Division, Azienda Ospedaliero-Universitaria Policlinico di Modena, Modena, Italy; 3Department of Medical and Surgical Sciences for Children and Adults, University of Modena and Reggio Emilia, Modena, Italy; 4Department of Biomedical, Metabolic and Neural Sciences, University of Modena and Reggio Emilia, Modena, Italy.
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PO:35:233 | Tocilizumab is associated with improved relapse-free survival in polymyalgia rheumatica: a multicentre retrospective study Milena Bond1, Giovanni Adami2, Marianna Tamussin3, Mario Frasca4, Sara Zandonella Callegher1, Marcello Govoni3, Maurizio Rossini2, Lorenzo Dagna4, Marco Matucci Cerinic4, Christian Dejaco1, Alessandro Tomelleri4 | 1Department of Rheumatology, Brunico Hospital ASAA-SABES, Teaching Hospital of the Paracelsius Medical University Bunico, Italy; 2Rheumatology Unit, University of Verona, Policlinico Borgo Roma Verona, Italy; 3Rheumatology Unit, Department of Medical Sciences, University of Ferrara and Azienda Ospedaliero-Universitaria S. Anna Ferrara, Italy; 4Unit of Immunology, Rheumatology, Allergy and Rare Diseases, IRCCS San Raffaele Hospital Milano, Italy
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PO:23:052 | Muscular and myocardial involvement in antisynthetase syndrome: a retrospective real-life study Giulia Buonsante1|2|3, Giacomo De Luca1|2|3, Veronica Batani1|2, Daniele Scaramuzzi1|2|3, Lorenzo Dagna1|2|3, Marco Matucci-Cerinic1|2|3, Corrado Campochiaro1|2|3. | 1Unit of Immunology, Rheumatology, Allergy and Rare Diseases UNIRAR, IRCCS San Raffaele Hospital, Milano, Italy; 2Inflammation, Fibrosis and aging Initiative INFLAGE, IRCCS San Raffaele Hospital, Milano, Italy; 3Vita-Salute San Raffaele University, Milan, Italy, Milano, Italy.
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PO:35:218 | Switching the dose of mepolizumab in patients with Eosinophilic Granulomatosis with Polyangiitis (EGPA): a European retrospective multicentre real-world study Edoardo Biancalana1, Irene Mattioli1, Emanuele Chiara2, Danilo Malandrino1, Maria Canfora1, Palmerini Miki1, Maria Paola Lisi1, Michela Gasparotto3, Paola Tomietto3, Maria Letizia Urban1, Giacomo Bagni1, Elena Silvestri1, Alessandra Bettiol3, Augusto Vaglio3, Giacomo Emmi2 | 1Department of Experimental and Clinical Medicine, University of Florence Firenze, Italy; 2Department of Medical, Surgery and Health Sciences, University of Trieste Trieste, Italy; 3Clinical Medicine and Rheumatology Unit, Cattinara University Hospital, Trieste, Trieste, Italy; 4Department of Biomedical, Experimental and Clinical Sciences Mario Serio, University of Florence Firenze, Italy
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PO:03:035 | Biomarkers of Gut Epithelial Damage, Microbial Translocation, and Innate Immune Activation Characterize Patients with Axial Psoriatic Arthritis from Psoriasis Patients: Soluble Biomarker Analysis Insights from the ATTRACT Study Giulia Marchionni1, Valentino Paci1, Silvia Svegliati1, Raffaella Sordillo1, Federico Fiorini1, Melania Giannoni1, Anna Campanati1, Raissa Di Zio1, Devis Benfaremo1, Giuseppe Lopalco2, Florenzo Iannone2, Ennio Lubrano3, Alberto Cauli4, Gianluca Moroncini1, Dennis Poddubnyy5, Fabian Proft6, Michele M Luchetti Gentiloni1 | 1Marche Polytechnic University and Azienda Ospedaliero-Universitaria delle Marche, Ancona, Italy; 2University of Bari, Bari, Italy; 3Molise University, Campobasso, Italy; 4University of Cagliari, Azienda Ospedaliero Universitaria di Cagliari, Monserrato, Italy; 5University of Toronto, Toronto, Canada; 6Charité-Universitätsmedizin, Berlino, Germany
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PO:37:263 | First non invasive visualization of vasculitis in the retinal arteries by high resolution optical coherence tomography in a patient with giant cell arteritis Ruggiero Mascolo1, Chiara Facoetti1, Claudia Nardi2, Stefano Erba2, Martina Martelli1, Gabriella Marinaro1, Giulia Dieguez1, Giacomo Iacomelli1, Chiara Carollo1, Michel Chevallard3, Bruno Lucchino3, Mariaeva Romano3, Andrea Locatelli3, Donatella Ventura3, Giovanna Randisi3, Giuliana La Paglia3, Alessandra Mutti3, Alessandro Invernizzi2, Stefano De Angelis2, Giovanni Staurenghi2, Antonio Brucato4, Enrico Tombetti4. | 1Dipartimento di Medicina Interna, ASST Fatebenefratelli-Sacco, Università degli studi di Milano, Milano, Italy; 2U.O. Oftalmologia, ASST Fatebenefratelli-Sacco, Università degli studi di Milano, Milano, Italy; 3U.O. Reumatologia, ASST Fatebenefratelli-Sacco, Università degli studi di Milano, Milano, Italy; 4Dipartimento di scienze cliniche e biomediche, ASST Fatebenefratelli-Sacco, Università degli studi di Milano, Milano, Italy.
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PO:24:059 | Sjögren's disease-associated Fibromyalgia: pitfalls in disease assessment using ESSDAI and ESSPRI Lucia Cristiana Colaprico1, Stefano Stano1, Daniele Domanico1, Maria Iacovantuono2, Eduardo Urgesi3, Fabio Cacciapaglia1|4, Maria Giannotta1, Paola Conigliaro2, Vincenzo Venerito1, Maria Sole Chimenti2, Giuseppe Lopalco1, Florenzo Iannone1 | 1Rheumatology Unit - Department of Precision and Regenerative Medicine, Jonian Area DiPReMeJ, University of Bari, Bari, Italy; 2University of Rome Tor Vergata, Rheumatology, Allergology and Clinical Immunology, Department of Systems Medicine, Roma, Italy; 3University Cardiologic Unit - Interdisciplinary Department of Medicine - Policlinico University Hospital, University Bari, Italy; 4Rheumatology Service, Internal Medicine Unit F. Miulli General Hospital, Department of Medicine and Surgery, LUM Casamassima, Italy
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PO:34:209 | Increased liver stiffness and fibrosis in systemic sclerosis: a single-center transient elastography cohort study. Nicola Ortalli1|2, Simone Aldo Lari1|2, Alessandra Vacca3, Erika Meleddu1|2, Alberto Civolani4, Emanuela Vargiu4, Alberto Floris1|2, Massimo Claudio Fantini4, Alberto Cauli1|2. | 1Rheumatology Unit, Azienda Ospedaliero Universitaria di Cagliari, Cagliari, Italy; 2Department of Medical Sciences and Public Health, University of Cagliari, Cagliari, Italy; 3Rheumatology Unit, Presidio Ospedaliero CTO di Iglesias Iglesias Italy; 4Gastroenterology Unit, Azienda Ospedaliero Universitaria di Cagliari, Cagliari, Italy.
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