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PO:14:195 | Real-world effectiveness of anifrolumab in achieving treatment targets and reducing systemic lupus erythematosus disease burden: 6-month interim analysis of the REVEAL study Chiara Cardelli1|2, Chiara Tani1, Luca Moroni3, Filippo Vesentini4, Francesca Bottazzi5, Micaela Fredi6, Ettore Silvagni7, Matteo Piga8, Flavia Riccio9, Fulvia Ceccarelli10, Ginevra De Marchi11, Edoardo Biancalana12, Gianluca Moroncini13, Rita Mulè14, Mariele Gatto15, Laura Coladonato16, Paola Conigliaro17, Maria Gerosa18, Andrea Picchianti Diamanti19, Benedetta Bianchi20, Federica Maiolini20, Michela Gasparotto20, Serena Guiducci20, Maria Ilenia De Andres20, Alberto Lo Gullo20, Silvia Noviello20, On Behalf Of The Reveal Investigators20, Marta Mosca1. | 1Rheumatology Unit, Department of Clinical and Experimental Medicine, University of Pisa, Pisa; 2Department of Medical Biotechnologies, University of Siena, Siena; 3Unit of Immunology, Rheumatology, Allergy and Rare Diseases, IRCCS San Raffaele Hospital, Milano; 4Rheumatology Unit, Department of Medicine, University of Padua, Padova; 5Department of Internal Medicine and Therapeutics, University of Pavia, Pavia; 6Rheumatology and Clinical Immunology, Department of Clinical and Experimental Sciences, University of Brescia, Brescia; 7Section of Rheumatology, Department of Medical Sciences, University of Ferrara; AOU Sant'Anna, Ferrara; 8Rheumatology Unit, Department of Medical Sciences and Public Health, University of Cagliari, Cagliari; 9Department of Precision Medicine, University of Campania Luigi Vanvitelli, Napoli; 10Rheumatology Unit, Dept. of Clinical Internal, Anesthesiological and Cardiovascular Sciences, Sapienza University of Rome, Roma; 11Division of Rheumatology, Department of Medicine, Azienda Sanitaria Universitaria del Friuli Centrale, Udine; 12Internal Interdisciplinary Medicine Unit, Department of Experimental and Clinical Medicine, University of Florence, Firenze; 13Department of Clinical and Molecular Sciences, Marche Polytechnic University, Ancona; 14Azienda Ospedaliero-Universitaria di Bologna, Internal Medicine and Rheumatology, IRCCS S. Orsola Malpighi, Bologna; 15Academic Rheumatology Centre, Department of Clinical and Biological Sciences, University of Turin; AO Mauriziano, Torino; 16Rheumatology Unit, Department of Precision and Regenerative Medicine and Ionian Area, University of Bari, Bari; 17Rheumatology, Allergology and Clinical Immunology, Department of Systems Medicine, Tor Vergata University of Rome, Roma; 18Clinical Rheumatology, ASST Gaetano Pini CTO; Department of Clinical Sciences and Community Health, University of Milano, Milano; 19Department of Clinical and Molecular Medicine, Sapienza University of Rome; AOU Sant'Andrea, Roma, Italy; 20Italian REVEAL Study Group Italy, Italy
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PO:31:165 | Prevalence and incidence of skin telangectasia and their association with clinical features: analysis of the European Scleroderma Trials and Research cohort Gemma Lepri1, Lorenzo Tofani2, Silvia Bellando Randone1, Veronica Batani3, Paolo Airò4, Patricia Carreira5, Joerg Henes6, Alexandra Balbir Gurman7, Florenzo Iannone8, Antonella Marcoccia9, Luc Mouthon10, Branimir Anic11, Carolina De Souza Müller12, Armine Haroyan13, Ana Cristina Cordeiro14, Serena Guiducci And Eustar Coll1. | 1University of Florence, Dept of Experimental and Clinical Medicine, AOU Careggi, Division of Rheumatology Florence Italy; 2University of Florence, Dept of Statistics, Informatics, Applications, Florence, Italy; 3Unit of Immunology, Rheumatology, Allergy and Rare Diseases UnIRAR, IRCCS San Raffaele, Milano, Italy; 4Scleroderma Unit, UOC Rheumatology and Clinical Immunology, ASST Spedali Civili, Brescia, Italy; 5Dept of Rheumatology, 12 de Octubre University Hospital, Madrid, Spain; 6Centre for Interdisciplinary Rheumatology, Immunology and autoimmune diseases INDIRA, University Hospital Tuebingen, Tuebingen, Germany; 7Rheumatology Institute, Rambam Health Care Campus Haifa Israel; 8Dept of Precision and Regenerative Medicine and Ionian Area, University of Bari, Bari, Italy; 9Interdisciplinary Reference Center for Systemic Sclerosis CRIIS Sandro Pertini Hospital, Rome, Italy; 10Dept of Internal Medicine, Cochin Hospital, Paris Cité University, Paris, France; 11Div Clinical Immunology and Rheumatology, Dept Internal Medicine, School of Medicine, University Hospital Center Zagreb, Zagreb, Croatia; 12Rheumatology Division, Hospital de Clínicas da Universidade Federal do Parana, Curitiba, Brazil; 13Dept of Rheumatology, Yerevan State Medical University of Armenia, Yerevan, Armenia; 14Servico Reumatologia Hospital Garcia de Orta Almada, Almada, Portugal.
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PO:01:003 | Sex-based differences in 2 years treatment outcomes with b/ts-DMARDs in psoriatic arthritis: from real-world evidence to predictive modeling from the Gruppo Italiano Studio Early Arthritis (GISEA) prospective registry Simone Perniola1, Florenzo Iannone1, Francesco Paolo Cantatore2, Angelo Semeraro3, Leonardo Santo4, Roberto Gorla5, Alberto Cauli6, Roberto Felice Caporali7, Bruno Frediani8, Rosario Foti9, Fabrizio Conti10, Marco Sebastiani11, Maria Sole Chimenti12, Roberta Ramonda13, Fabiola Atzeni14, Maurizio Rossini15, Serena Bugatti16, Serena Guiducci17, Giovanni Lapadula1, Gianfranco Ferraccioli18, Francesca Romana Spinelli10, Elisa Gremese19. | 1Rheumatology Unit, DiMePReJ, University of Bari, Bari; 2Rheumatology Unit, Department of Medical and Surgical Sciences, Azienda Ospedaliero-Universitaria Policlinico Riuniti, Foggia; 3Rheumatology Unit, Martina Franca Hospital; 4Rheumatology Unit, ASL BT, P.O. Barletta; 5Rheumatology and Clinical Immunology Unit, ASST Spedali Civili of Brescia; 6Rheumatology Unit, Department of Medical Science and Public Health, University of Cagliari, Monserrato (CA); 7Rheumatology Unit, Dipartimento di Reumatologia e Scienze Mediche, ASST PINI-CTO, University of Milano, Milano; 8Rheumatology Unit, Azienda Ospedaliero Universitaria Senese, Siena; 9Rheumatology Unit, A.O.U. Policlinico S. Marco, Catania; 10Rheumatology Unit, Department of Clinical Internal, Anesthesiologic and CV Sciences, Sapienza University of Rome, Roma; 11Rheumatology Unit, AUSL Piacenza, University of Parma, Parma; 12Rheumatology, Department of Systems Medicine, University of Rome Tor Vergata, Roma; 13Rheumatology Unit, DIMED, University of Padua, Padova; 14Rheumatology Unit, Department of Experimental and Internal Medicine, University of Messina, Messina; 15Rheumatology Unit, Department of Medicine, University of Verona, Verona; 16Division of Rheumatology, Dept. of Internal Medicine and Therapy, Fondazione IRCCS Policlinico S. Matteo, University of Pavia, Pavia; 17Division of Rheumatology, Department of Experimental and Clinical Medicine, University of Firenze, Firenze; 18Department of Medicine, Catholic University of the Sacred Heart, Fondazione Policlinico Gemelli IRCCS, Roma; 19Rheumatology and Clinical Immunology, IRCCS Humanitas Research Hospital, Humanitas University, Rozzano (MI), Italy
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PO:33:199 | Prevalence and clinical associations of antiphospholipid antibodies in patients with systemic sclerosis in the SPRING-SIR registry Antonio Tonutti1|2, Ilaria Cavazzana3, Angela Ceribelli1|2, Maria De Santis1|2, Giacomo De Luca4|5, Maria Grazia Lazzaroni3, Franco Franceschini3, Carlo Selmi1|2, Valeria Riccieri6, Silvia Laura Bosello7, Fabio Cacciapaglia8, Veronica Codullo9, Francesca Ingegnoli10, Dilia Giuggioli11, Rossella De Angelis12, Clodoveo Ferri11, Marco Matucci-Cerinic4|5 | 1Department of Biomedical Sciences, Humanitas Universityce Pieve Emanuele, Milan, Italy; 2Rheumatology and Clinical Immunology, IRCCS Humanitas Research Hospital Rozzano, Milan, Italy; 3Rheumatology and Clinical Immunology - ASST Spedali Civili Brescia - Department of Clinical and Experimental Sciences - Brescia, Italy; 4Vita-Salute San Raffaele University Milan, Italy; 5Unit of Immunology, Rheumatology, Allergy and Rare Diseases UnIRAR and INFLAGE Initiative, IRCCS San Raffaele Hospital Milan, Italy; 6University of Rome La Sapienza Rome, Italy; 7Catholic University of Sacred Heart Rome, Italy; 8LUM University Bari, Italy; 9Rheumatology Unit, Fondazione IRCCS Policlinico San Matteo Pavia, Italy; 10University of Milan Milan, Italy; 11University of Modena and Reggio Emilia Modena, Italy; 12Politechnic University of Marche Ancona, Italy
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CO:08:5 | Clinical impact of anti-Ro52 antibodies in idiopathic inflammatory myopathies: insights from a multicenter Italian cohort Paola Bizioli1, Cesare Tomasi2, Francesca Bellisai3, Francesca Buzzulini4, Antonio Tonutti5|6, Angela Ceribelli5|6, Edoardo Conticini3, Anna Ghirardello7, Luca Iaccarino7, Danilo Villalta4, Franco Franceschini1, Ilaria Cavazzana1. | 1Rheumatology and Clinical Immunology Unit - ERN ReCONNET, ASST Spedali Civili of Brescia; 2Department of Clinical and Experimental Sciences, University of Brescia; 3Department of Medicine, Surgery and Neurosciences, Rheumatology Unit, University of Siena; 4Department of Laboratory Immunology and Allergology, Santa Maria degli Angeli Hospital, Pordenone; 5Department of Biomedical Sciences, Humanitas University, Rozzano (MI); 6Rheumatology and Clinical Immunology, Istituti di Ricovero e Cura a Carattere Scientifico, Humanitas Research Hospital, Rozzano (MI); 7Division of Rheumatology, Department of Medical and Surgical Sciences, University of Padova, Italy
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PO:06:079 | Weighing the burden: how body mass index shapes clinical outcomes in rheumatoid arthritis. Insights from a large Italian cohort Marco Capodiferro1, Marco Fornaro1, Gian Luca Erre2, Matteo Piga3, Elena Bartoloni Bocci4, Andreina Manfredi5, Ennio Giulio Favalli6, Maria Sole Chimenti7, Serena Guiducci8, Eleonora Celletti9, Addolorata Corrado10, Alessandro Giollo11, Simone Parisi12, Ivan Giovannini13, Elisa Gremese14, Garifallia Sakellariou15, Ombretta Viapiana16, Fabiola Atzeni17, Francesca Romana Spinelli18, Fabio Cacciapaglia1|19. | 1Rheumatology Unit, Department of Precision and Regenerative Medicine and Ionian Area DiMePRe-J University of Bari, Bari, Italy; 2Dipartimento di Scienze Mediche, Chirurgiche e Sperimentali, Università degli Studi di Sassari, Sassari, Italy; 3Rheumatology Unit, AOU Cagliari, Department of Medical Sciences and Public Health, University of Cagliari, Cagliari, Italy; 4Rheumatology Unit, Department of Medicine and Surgery, University of Perugia, Perugia, Italy; 5Rheumatology Unit, Azienda Ospedaliera Universitaria Policlinico of Modena, Modena, Italy; 6Dpt of Rheumatology, G. Pini Institute, Milano, Italy; 7Rheumatology, Allergology and Clinical Immunology, Department of Systems Medicine, University of Rome Tor Vergata, Rome, Italy; 8Department of Experimental and Clinical Medicine, Division of Rheumatology, University of Florence, Firenze, Italy; 9Rheumatology Unit, SS Annunziata Hospital, Chieti, Italy; 10Rheumatology Unit, Department of Medical and Surgical Sciences, University of Foggia, Foggia, Italy; 11Rheumatology Unit, Department of Medicine, University of Padova Hospital Trust, Padova, Italy; 12Rheumatology Department, A.O.U. Città della Salute e della Scienza, Torino, Italy; 13Rheumatology Department, Santa Maria della Misericordia Hospital, Udine, Italy; 14Rheumatology and Clinical Immunology, IRCCS Humanitas Research Hospital, Rozzano (MI), Italy; 15Department of Internal Medicine and Therapeutics, University of Pavia, Istituti Clinici Scientifici Maugeri, Pavia, Italy; 16Rheumatology Unit, Department of Medicine, University and Azienda Ospedaliera Universitaria Integrata of Verona, Verona, Italy; 17Rheumatology Unit, Department of Experimental and Internal Medicine, University of Messina, Messina, Italy; 18Reumatology Unit, Department of Internal, Anesthesiological, and Cardiovascular Clinical Sciences, Sapienza University, Roma, Italy; 19Miulli General Hospital Acquaviva - Department of Medicine and Surgery, LUM F. De Gennaro University, Casamassima (BA), Acquaviva delle Fonti (BA), Italy.
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PO:15:219 | Nailfold capillaroscopic abnormalities in systemic lupus erythematosus: comparison with healthy controls and clinical-immunological correlations. Preliminary data Chiara Orlandi1|2, Alessia Loda2, Cesare Tomasi1|2, Silvia Ebe Lucia Della Pina1|2, Claudia Barison1|2, Cecilia Nalli1, Ilaria Cavazzana1|2, Micaela Fredi1|2, Franco Franceschini1|2. | 1Rheumatology and Clinical Immunology Unit - ERN ReCONNET , ASST Spedali Civili of Brescia, Brescia, Italy; 2Department of Clinical and Experimental Sciences, University of Brescia, Brescia, Italy.
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PO:35:219 | Real-world effectiveness of mepolizumab on gastrointestinal involvement in eosinophilic granulomatosis with polyangiitis and hypereosinophilic syndrome: a multicentre retrospective study Alessia Gatti1, Francesca Regola1, Giulia Fontana1, Mario Addrea Piga2, Gianluca Moroncini2, Palma Carlucci3, Angelo Vacca3, Paolo Delvino4, Enrico Heffler5, Emanuele Nappi5, Jakub Moll6, Laura Losappio6, Jan Schroeder6, Federica Davanzo7, Roberto Padoan7, Edoardo Conticini8, Paolo Cameli8, Greta Pacini9, Alvise Berti9, Lorenzo Vrola10, Paola Tomietto10, Luca Quartuccio11, Jan Willem Cohen Tervaert12, Sabrina Arnold13, Peter Lamprecht13, Florence Roufosse14, Ilaria Cavazzana1, Franco Franceschini1, Giacomo Emmi15, Paola Toniati1. | 1Rheumatology and Clinical Immunology Unit, ERN ReCONNET, ASST Spedali Civili of Brescia and University of Brescia, Italy, Brescia, Italy; 2Università Politecnica delle Marche and Azienda Ospedaliero Universitaria delle Marche, Ancona, Italy, Ancona, Italy; 3Section of Internal Medicine 'Guido Baccelli', DiMePRe-J, University of Bari 'Aldo Moro', Bari, Italy, Bari, Italy; 4Rheumatology Unit, IRCCS San Gerardo dei Tintori, Monza, Italy Monza Italy; 5Department of Biomedical Sciences, Humanitas University and Personalized Medicine, Asthma and Allergy IRCCS Humanitas, Milano, Italy; 6Division of Allergy and Clinical Immunology, ASST GOM Niguarda, Milan, Italy, Milano, Italy; 7Rheumatology Unit, Department of Medicine DIMED, University of Padua, Padova, Italy, Padova, Italy; 8University of Siena, Siena, Italy, Siena, Italy; 9Santa Chiara Hospital and University of Trento, Unit of Rheumatology, Trento, Italy Trento Italy; 10UCO Medicina Clinica, ASUGI, Cattinara Teaching Hospital, Trieste, Italy, Trieste, Italy; 11Division of Rheumatology, Department of Medicine DMED, University of Udine, Udine, Italy, Udine, Italy; 12University of Alberta, Edmonton, Alberta, Canada and Maastricht University, Maastricht, The Netherlands Maastricht The Netherlands; 13Department of Rheumatology and Clinical Immunology, University of Lübeck, Lübeck, Germany Lubeck Germany; 14Department of Internal Medicine, Hôpital Universitaire de Bruxelles - Erasme, Université Libre de Bruxelles, Belgium Brussels Belgium; 15Clinical Medicine and Clinical Immunology and Rheumatology Unit Cattinara University Hospital and University of Trieste, Trieste, Italy.
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PO:19:286 | Genetic testing reveals an unexpected case of mevalonate kinase deficiency in a 37-year-old patient with AA renal amyloidosis and good response to colchicine Francesca Crisafulli1, Paolo Airò2, Federica Mescia3, Gianmarco Lugli3, Gianfranco Savoldi4, Claudia Izzi3|5, Federico Alberici3, Marco Cattalini6, Franco Franceschini1, Micol Frassi2. | 1Rheumatology and Clinical Immunology Unit, ASST Spedali Civili and University of Brescia, Brescia, Italy; 2Rheumatology and Clinical Immunology Unit, ASST Spedali Civili of Brescia, Brescia, Italy; 3U.O Nefrologia, ASST Spedali Civili di Brescia e Università degli Studi di Brescia, Brescia, Italy; 4Medical genetics Laboratory, Laboratory Department ASST Spedali Civili di Brescia, Brescia, Italy; 5Struttura Complessa di Genetica Clinica, ASST Spedali Civili di Brescia, Brescia, Italy; 6Pediatrics Clinic, University of Brescia and ASST Spedali Civili of Brescia, Brescia, Italy.
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PO:31:175 | Characterizing gastrointestinal involvement in systemic sclerosis: insights from the national systemic sclerosis progression investigation registry of the Italian Society of Rheumatology Francesco Bonomi1, Cosimo Bruni1|2, Silvia Laura Bosello3, Fabio Cacciapaglia4|5, Corrado Campochiaro6, Roberto Caporali7, Veronica Codullo8, Maria Antonietta D'Agostino3, Lorenzo Dagna6, Rossella De Angelis9, Giacomo De Luca6, Dilia Giuggioli10, Serena Guiducci1, Florenzo Iannone4, Francesca Ingegnoli7, Carlomaurizio Montecucco8, Valeria Riccieri11, Clodoveo Ferri10, Marco Matucci Cerinic6, Silvia Bellando Randone1. | 1Scleroderma Unit, Division of Rheumatology AOUC, and Department of Experimental and Clinical Medicine, Uni. of Florence, Firenze, Italy; 2Department of Rheumatology, University Hospital Zurich, University of Zurich Zurigo Switzerland; 3UOC of Rheumatology and Clinical Immunology, Catholic University of the Sacred Heart, Fondazione Policlinico A. Gemelli, Roma, Italy; 4Rheumatology Unit, Department of Emergency Surgery and Organ Transplantations, University of Bari, Bari, Italy; 5Rheumatology Service, F. Miulli General Hospital - Department of Medicine and Surgery, LUM 'G. De Gennaro', Casamassima, Italy; 6Unit of Immunology, Rheumatology, Allergy and Rare Diseases and Inflammation, fibrosis and ageing initiative, UniSR, Milano, Italy; 7Division of Clinical Rheumatology, ASST Pini and Università degli studi di Milano, Milano, Italy; 8Department of Rheumatology, Policlinico San Matteo, Pavia, Italy; 9Rheumatology Unit, Department of Clinical and Molecular Sciences, Polytechnic University of Marche, Ancona, Italy; 10Rheumatology Unit, School of Medicine, University of Modena and Reggio Emilia, Modena, Italy; 11Department of Rheumatology, Sapienza University of Rome, Roma, Italy.
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PO:33:190 | Travel distance to tertiary healthcare reflects disease severity and medication access in systemic sclerosis patients: insights from the Italian systemic sclerosis progression investigation registry of the Italian Society of Rheumatology Camilla Teresa Magnanimi1, Enrico De Lorenzis1, Gerlando Natalello1, Fabio Cacciapaglia2, Rossella De Angelis3, Edoardo Cipolletta3, Maria Antonietta D'Agostino1, Veronica Cudullo4, Giacomo De Luca5, Dilia Giuggioli6, Francesca Ingegnoli7, Valeria Riccieri8, Lorenzo Dagna5, Fiorenzo Iannone9, Clodoveo Ferri6, Marco Matucci Cerinic5, Silvia Laura Bosello1. | 1Division of Rheumatology and Clinical Immunology, Catholic University of the Sacred Heart, Fondazione Policlinico Univer, Roma, Italy; 2Department of Medicine and Surgery, LUM University Giuseppe De Gennaro Casamassima e Rheumatology Service Miulli Ge, Bari, Italy; 3Rheumatology Unit - Department of Clinical and Molecular Sciences, Polytechnic University of Marche, Ancona, Italy; 4Department of Rheumatology, Policlinico San Matteo, Pavia, Italy; 5Unit of Immunology, Rheumatology, Allergy and Rare Diseases UnIRAR, IRCCS San Raffaele Scientific Institute, Vita-Salu, Milano, Italy; 6Rheumatology Unit, School of Medicine, University of Modena and Reggio Emilia, Modena, Italy; 7Division of Clinical Rheumatology, ASST Pini, Dept. of Clinical Sciences e Community Health, Research Center for Adult a, Milano, Italy; 8Department of Rheumatology, La Sapienza University of Rome, Roma, Italy; 9Rheumatology Unit, Department of Precision and Regenerative Medicine and Ionian Area, University of Bari, Bari, Italy.
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CO:10:4 | Lung vasculature quantification on computed tomography predicts new onset of interstitial lung disease in systemic sclerosis Maria Iacovantuono1|2, Nicholas Landini2|3, Lisa Jungblut4, Gesa Sauer2, Rucsandra Dobrota2, Maria Sinziana Muraru-Carbune2, Muriel Elhai2, Carmen-Marina Mihai2, Mike Oliver Becker2, Maria Sole Chimenti1, Thomas Frauenfelder4, Anna-Maria Hoffmann-Vold5, Oliver Distler2, Cosimo Bruni2. | 1Rheumatology, Allergology and Clinical Immunology, Department of Systems Medicine, Tor Vergata University, Rome, Italy; 2Department of Rheumatology, University Hospital Zurich, University of Zurich, Switzerland; 3Department of Radiological Sciences, Oncology and Pathology, Sapienza University, Policlinico Umberto I, Rome, Italy; 4Institute for Diagnostic and Interventional Radiology, University Hospital Zurich, University Zurich, Switzerland; 5Department of Rheumatology, Oslo University Hospital, Norway
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CO:06:1 | Predictors of damage accrual in a monocentric cohort of patients with Behçet’s syndrome (BS) evaluated with BS overall damage index in real-life clinical practice Giulia Voltarel1|2, Francesca Crisafulli1|2, Alba Chiara Pozzi1|2, Anita Melzani2, Micol Frassi1, Ilaria Cavazzana1|2, Franco Franceschini1|2, Paolo Airò1. | 1Rheumatology and Clinical Immunology Unit - ERN ReCONNET, ASST Spedali Civili of Brescia; 2Department of Clinical and Experimental Sciences, University of Brescia, Italy
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S13:5 | Association between vasoactive-vasodilating therapy and reduced detection of pulmonary arterial hypertension in systemic sclerosis: evidence from a European Scleroderma Trials and Research study Nicola Farina1, Silvia Bellando-Randone1, Sebastien Sanges2, Hilde Jenssen Bjørkekjær3, Lorenzo Tofani4, Marie-Elise Truchetet5, Vanessa Smith6, Andra Balanescu7, Christina Bergmann8, Yannick Allanore9, Philipp Klemm10, Simona Truglia11, Luca Idolazzi12, Christopher Denton13, Roberta Foti14, Anna Wojteczek15, Emmanuel Chatelus16, Madelon Vonk17, Serena Guiducci1, David Launay2, Eric Hachulla2, Jeska De Vries-Bouwstra18, Anna-Maria Hoffmann-Vold19, Oliver Distler20, Marco Matucci-Cerinic1, Cosimo Bruni1. | 1Department of Experimental and Clinical Medicine, Scleroderma Unit, Division of Rheumatology, University of Florence, Az, Firenze, Italy; 2Univ. Lille, Inserm, CHU Lille, Department of Internal Medicine and Clinical Immunology, Reference Center for Rare Autoi, Lille, France; 3Department of Rheumatology, Hospital of Southern Norway, Kristiansand, Norway; 4Department of Statistics, Informatics and Applications, University of Florence, Firenze, Italy; 5Rheumatology department, CHU de Bordeaux, Bordeaux, France; 6University of Ghent, Department of Rheumatology, Gent, Belgium; 7Department of Rheumatology, St. Maria Hospital, Carol Davila, University of Medicine and Pharmacy Bucharest Romania; 8Department Internal Medicine 3, University Hospital Erlangen, Erlangen, Germany; 9Rheumatology Department, Université Paris Cité, Cochin Hospital, Paris, France; 10Department of Rheumatology and Clinical Immunology Center, JLU Giessen, Campus Kerckhoff Bad Nauheim Germany; 11Reumatologia, Azienda Ospedaliero-Universitaria Policlinico Umberto I, Roma, Italy; 12Section of Rheumatology, Department of Medicine, University of Verona, Verona, Italy; 13Centre for Rheumatology, Royal Free London and University College London Medical School, London, United Kingdom; 14Division of Rheumatology, A.O.U. Policlinico-San Marco, Catania, Italy; 15Department of Rheumatology, Clinical Immunology, Geriatrics and Internal Medicine, Medical University of Gdansk, Univers Gdansk Poland; 16Department of Rheumatology, University Hospital Strasbourg Strasbourg France; 17Department of rheumatology, Radboud University Nijmegen Medical Center Nijmegen The Netherlands; 18Department of Rheumatology, Leiden University Medical Center Leiden The Netherlands; 19Department of Rheumatology, Oslo University Hospital, Oslo, Norway; 20Department of Rheumatology, University Hospital Zurich, University of Zurich, Zurich, Switzerland.
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PO:02:016 | Real-world evidence of upadacitinib over two years in Italian patients with axial spondyloarthritis Mariagrazia Lorenzin1, Giacomo Cozzi1, Stefano Gentileschi2, Michele Maria Luchetti Gentiloni3, Antonio Carletto4, Maria Sole Chimenti5, Maria Manara6, Luca Quartuccio7, Rosario Foti8, Salvatore D'Angelo9, Ariela Hoxha10, Carlo Selmi11, Bernd Raffeiner12, Alessandro Giollo1, Alberto Cauli13, Carlo Salvarani14, Fabiola Atzeni15, Roberta Ramonda1, Sir Study Group Spa E Psa Antonio Spadaro16. | 1Rheumatology Unit, Department of Medicine DIMED, University of Padova, Padova, Italy; 2Rheumatology Unit, Department of Medicine, Surgery and Neurosciences, University of Siena, Siena, Italy; 3Clinica Medica, Ospedali Riuniti Ancona University Hospital, Ancona; Department of Clinical and Molecular Sciences, Ancona, Italy; 4Rheumatology Unit, Department of Medicine, AOUI University of Verona, Verona, Italy; 5Rheumatology, allergology and clinical Immunology, Department of Systems Medicine, University of Rome Tor Vergata, Roma, Italy; 6Humanitas San Pio X, Milano, Italy; 7University of Udine, Academic Hospital Santa Maria della Misericordia, Udine, Italy; 8Rheumatology Unit, A.O.U. Policlinico S. Marco, Catania, Italy; 9Rheumatology Department of Lucania, San Carlo Hospital of Potenza and Madonna delle Grazie Hospital of Matera, Potenza, Italy; 10Internal Medicine Unit, Thrombotic and Hemorrhagic Center, Department of Medicine-DIMED, University of Padua, Padova, Italy; 11Department of Rheumatology and Clinical Immunology, IRCCS Humanitas Research Hospital, Rozzano, Milano, Italy; 12Department of Rheumatology, Teaching Hospital of the Paracelsius Medical Hospital of Bolzano ASAA-SABES, Bolzano, Italy; 13Rheumatology Unit, Department of Medical Sciences, AOU and University of Cagliari, Monserrato, Cagliari, Italy; 14Department of Rheumatology, Azienda USL-IRCCS di Reggio Emilia and Università di Modena and Reggio Emilia, Reggio Emilia, Italy; 15Rheumatology Unit, University of Messina, Messina, Italy; 16Società Italiana di Reumatologia, Milano, Italy.
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PO:06:090 | Validation of 'Clinical Red Flags' for RA-ILD in an Italian cohort: the role fo Dyspnea, Cough and Crackles Eneida Cela1, Chiara Bonini1, Francesco Cavalli2, Alessandra Luciano3, Barbara Kroegler1, Josuel Ora2, Alberto Bergamini1, Marcello Chiocchi3, Paola Rogliani2, Paola Conigliaro1, Maria Sole Chimenti1 | 1Rheumatology, Allergology and Clinical Immunology, Department of System Medicine, University of Rome Tor Vergata, Rome, Italy; 2Division of Respiratory Medicine, University Hospital Policlinico Tor Vergata, Rome, Italy; 3Department of Diagnostic Imaging and Interventional Radiology, University of Rome, Tor Vergata, Rome, Italy
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CO:06:3 | Clinical and laboratory markers for distinguishing VEXAS from Schnitzler's syndrome in male patients with skin involvement: insights from the International AIDA Network Registries Valeria Caggiano1, Jessica Sbalchiero1, Micol Frassi2, Andrea Hinojosa-Azaola3, Francesca Crisafulli2, Franco Franceschini2, Paolo Sfriso4, Sara Bindoli4, José Hernández-Rodríguez5, Henrique A. Mayrink Giardini6, Giuseppe Lopalco7, Florenzo Iannone7, Ombretta Viapiana8, Amato De Paulis9, Lorenzo Dagna10, Antonio Gidaro11, Serena Bugatti12, Matteo Piga13, Fabrizio Conti14, Rosetta Vitetta15, Cecilia Chighizola16, Marcello Govoni17, Giacomo Emmi18, Paola Triggianese19, Carmelo Gurnari19, Bruno Frediani1, Claudia Fabiani1, Luca Cantarini1, Antonio Vitale1, for the AIDA Network1 | 1Department of Medical Sciences, Surgery and Neurosciences, University of Siena; 2University of Brescia, Italy; 3Department of Immunology and Rheumatology, Mexico City, Mexico; 4Rheumatology Unit, University of Padova, Italy; 5Clinical Unit of Autoinflammatory Diseases, Hospital Clínic of Barcelona, Spain; 6Rheumatology Division, Universidade de São Paulo, Brazil; 7University of Bari; 8Rheumatology Unit, University and Azienda Ospedaliera Universitaria Integrata of Verona; 9University of Napoli "Federico II"; 10Università Vita-Salute San Raffaele, Milano; 11Luigi Sacco Hospital, University of Milano; 12Università di Pavia; 13University and AOU of Cagliari; 14AOU Policlinico Umberto I, Sapienza University of Rome; 15Unit of Rheumatology, ASL Sant' Andrea Hospital, Vercelli; 16University of Milano; 17Azienda Ospedaliero-Universitaria S. Anna, Ferrara; 18University of Trieste; 19University of Rome-Tor Vergata, Rome, Italy.
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PO:07:099 | Survival on therapy of certolizumab pegol in rheumatoid arthritis, psoriatic arthritis, and spondyloarthritis: 8-year data from an Italian multicenter register Maria Manara1, Gilberto Cincinelli1|2, Marco Fornaro3, Simone Perniola4, Elisa Gremese5, Chiara Bazzani6, Serena Bugatti7, Francesca Romana Spinelli8, Rosario Foti9, Marco Sebastiani10, Alberto Cauli11, Fabiola Atzeni12, Giovanni Lapadula13, Gianfranco Ferraccioli14, Fabrizio Conti8, Florenzo Iannone3, Roberto Caporali1|2 | 1Department of Rheumatology and Medical Sciences, ASST G. Pini-CTO Milano; 2Department of Clinical Sciences and Community Health, University of Milan; 3Department of Precision and Regenerative Medicine and Ionian Area, University of Bari; 4Clinical Immunology Division, Fondazione Policlinico Universitario A. Gemelli IRCCS, Roma; 5Rheumatology and Clinical Immunology, IRCCS Humanitas Research Hospital, Rozzano (MI); 6Unit of Rheumatology and Clinical Immunology, ASST Spedali Civili Brescia; 7Department of Internal Medicine and Therapeutics, Università di Pavia; 8Rheumatology Unit, Dipartimento Scienze Cliniche Internistiche, Anestesiologiche e Cardiovascolari, Sapienza University, Roma; 9Rheumatology Unit, San Marco Hospital, Policlinico University of Catania; 10Rheumatology Unit, AUSL Piacenza, University of Parma; 11UOC di Reumatologia, Dipartimento di Scienze Mediche e Sanità Pubblica, Azienda Ospedaliero-Universitaria di Cagliari; 12Rheumatology Unit, Department of Experimental and Internal Medicine, University of Messina; 13Gruppo Italiano di Studio sulla Early Arthritis, GISEA, Bari; 14Department of Medicine, Università Cattolica del Sacro Cuore, Fondazione IRCCS Policlinico Gemelli, Roma, Italy
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CO:01:4 | Identify predictors of relapse in idiopathic inflammatory myopathies: insights from an international cohort Cristina Bochicchio1|2, Maria Rosa Pellico1|2, Claudia Iannone1|2, Lekshmi Minikumari Rahulan3, Marco Fornaro4, Ilaria Cavazzana5, Edoardo Conticini6, Musataka Musataka7, Akira Yoshida7, Silvia Cavalli1|2, Silvia Grazzini6, Giulio Fraticelli8, Alessia Gatti5, Giulio Lopinto4, Paolo Semeraro5, Veronica Batani8, Thomas Patric Sheeran9, Florenzo Iannone4, Giacomo De Luca8, Roberto Caporali1|2, Latika Gupta9|10|11, Nicoletta Del Papa2. | 1Department of Clinical Sciences and Community Health, University of Milano; 2Department of Rheumatology and Medical Sciences, ASST Gaetano Pini-CTO Institute, Milano, Italy; 3Rheumatology "Sanjay Gandhi" Postgraduate Institute of Medical Sciences, Lucknow, Uttar Pradesh, India; 4Unit of Rheumatology, Department of Precision and Regenerative Medicine, Area Jonica, University of Bari; 5Rheumatology and Clinical Immunology Unit, ASST Spedali Civili di Brescia; 6Rheumatology Unit, Department of Medicine, Surgery and Neurosciences, University of Siena, Italy; 7Department of Allergy and Rheumatology Nippon Medical School Graduate School of Medicine, Tokyo, Japan; 8Unit of Immunology, Rheumatology, Allergy and Rare Diseases, IRCCS San Raffaele Hospital, Milano, Italy; 9Department of Rheumatology, Royal Wolverhampton Hospitals NHS Trust, Wolverhampton, UK; 10Francis Crick Institute, London, UK; 11School of Infection, Inflammation and Immunology, College of Medicine and Health, University of Birmingham, UK
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PO:15:214 | Identification of SLE patients with high-levels Type 2 SLE through the polysymptomatic distress scale (PSD): correlations with other PROs and differences in clinical phenotypes in a multicentric cohort Micaela Fredi1|2, Giorgia Gozzoli1|2, Federica Bonaso1|2, Silvia Ebe Della Pina1|2, Claudia Barison1|2, Irene Lorenzini2, Anna Mattiuzzo2, Raffaele Pericotti2, Marcelo Neto3, Sofia Avedo4, Clàudia Oliveira4, Luis Sousa Ines3, Franco Franceschini1|2 | 1Rheumatology and Clinical Immunology, ASST Spedali Civili of Brescia, ERN-ReCONNET Center, Brescia, Italy; 2Department of Clinical and Experimental Sciences, University of Brescia, Brescia, Italy; 3Rheumatology Department, Centro Hospitalar Universitário de Coimbra - ULS Coimbra, Coimbra, Portugal; 4Rheumatology Department, ULS Aveiro, Aveiro, Portugal
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PO:16:232 | Belimumab step-down dose spacing in patients with systemic lupus erythematosus in persistent clinical remission: experience from a multicentric cohort Alice Bartoletti1, Laura Giudice1, Lorenza Maria Argolini1|2, Giuseppe Alvise Ramirez3, Luca Moroni3, Tommaso Schioppo4, Chiara Bellocchi5|6, Annalaura Fasiello6, Lorenzo Beretta6, Lorenzo Dagna3, Roberto Caporali1, Maria Gerosa1. | 1UO Clinica Reumatologica, ASST Gaetano Pini CTO, Milano, Italy; 2UOC Medicina fisica e riabilitazione specialistica, ASST Gaetano Pini CTO, Milano, Italy; 3Unit of Immunology, Rheumatology, Allergy and Rare Diseases, IRCCS San Raffaele Hospital, Vita-Salute San Raffa Milano Italy; 4Medicina Generale II, Servizio di Reumatologia, Ospedale San Paolo, ASST Santi Paolo Carlo, Milano, Italy; 5Department of Clinical Sciences and Community Health, University of Milan, Dipartimeto di Eccellenza 2023-2027, Milano, Italy; 6Referral Centre for Systemic Autoimmune DIseases, Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico, Milano, Italy
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PO:16:227 | Anifrolumab for Systemic Lupus Erythematosus: Preliminary Safety and Efficacy Findings from the Italian Experience Paola Bizioli1|2, Chiara Orlandi1|2, Claudia Barison1|2, Cesare Tomasi3, Alessia Caproli1, Silvia Piantoni1|2, Simona Signorini4, Emirena Garrafa4, Cecilia Nalli1, Micol Frassi1, Ilaria Cavazzana1|2, Micaela Fredi1|2, Franco Franceschini1|2 | 1Rheumatology and Clinical Immunology Unit - ERN ReCONNET, ASST Spedali Civili of Brescia, Italy; 2Department of Clinical and Experimental Sciences, University of Brescia, Italy; 3Department of Clinical and Experimental Sciences, University of Brescia, Italy; 4Laboratory of Clinical Chemistry, Department of Molecular and Translational Medicine, University of Brescia, Italy
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PO:16:238 | Cardiovascular risk in systemic lupus erythematosus patients: comparison among Framingham Score, QRISK3, and SLECRE Francesca Vignoni1|2, Serena Iodice2, Cesare Tomasi2, Chiara Orlandi1|2, Eleonora Pedretti1, Micaela Fredi2, Franco Franceschini1|2, Ilaria Cavazzana1|2. | 1Rheumatology and Clinical Immunology Unit - ERN ReCONNET, ASST Spedali Civili of Brescia, Brescia, Italy; 2Department of Clinical and Experimental Sciences, University of Brescia, Brescia, Italy.
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PO:10:150 | A case of pulmonary hypertension in Whipple's disease Alba Chiara Pozzi1|2, Giulia Fontana1|2, Francesca Crisafulli1|2, Guarino Daniele3, Monica Salvi3, Massimiliano Palazzini3, Francesco Biagi4|5, Ilaria Cavazzana1|2, Franco Franceschini1|2, Micol Frassi1. | 1Rheumatology and Clinical Immunology Unit ERN-ReCONNECT, ASST Spedali Civili, Brescia, Italy; 2Department of Clinical Experimental Sciences, University of Brescia, Brescia; 3IRCCS Azienda Ospedaliero-Universitaria di Bologna, University of Bologna, Cardiology Unit, DIMEC, Bologna; 4University of Pavia, Department of Internal Medicine and Therapeutics, Pavia; 5Istituti Clinici Scientifici Maugeri IRCCS, Gastroenterology Unit of Pavia Institute, Pavia, Italy.
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PO:03:037 | The Impact of Peripheral Joint Involvement, Pain, and Inflammatory Bowel Diseases on Drug Persistence in Axial Psoriatic Arthritis Giuseppe Lopalco1, Sergio Del Vescovo1, Maria Sole Chimenti2, Giuliana Guggino3, Serena Guiducci4, Eleonora Celletti5, Alberto Cauli6, Luca Cantarini7, Valentino Paci8, Eneida Cela2, Lidia La Barbera3, Gemma Lepri4, Myriam Di Penta5, Alberto Floris6, Alice Agostinelli8, Vincenzo Venerito1, Michele Maria Luchetti8, Florenzo Iannone1 | 1Rheumatology Unit, Department of Precision and Regenerative Medicine and Ionian Area, Bari, Italy; 2Reumatology, Allergology and Clinical Immunology University of Rome Tor Vergata, Roma, Italy; 3Department of Health Promotion Sciences, Maternal and Infant Care, Internal Medicine and Medical Specialties, Palermo, Italy; 4Divisions of Internal Medicine and Rheumatology AOUC, Department of Experimental and Clinical Medicine, Firenze, Italy; 5Rheumatology Unit, SS. Annunziata Hospital of Chieti, G. D'Annunzio, Chieti, Italy; 6Department of Medical Science and Public Health, Cagliari, Italy; 7Policlinico Le Scotte, Siena, Italy; 8Clinical Medicine, Dipartimento di Scienze Cliniche e Molecolari, Università Politecnica delle Marche, Ancona, Italy
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PO:14:205 | Primary antiphospholipid antibody syndrome: association between new classification criteria manifestations and a higher-risk disease phenotype Sara Ferrigno1, Vittorio Forte2, Marco Panetta1, Sergio Lisena1, Giorgia Ranucci2, Luigi De Marco1, Elisabetta Greco1, Alberto Bergamini1, Maria Sole Chimenti1, Paola Conigliaro1. | 1Rheumatology, allergology and clinical immunology, Department of Systems Medicine, University of Rome Tor Vergata, Rome, Italy; 2Hematology, Department of Biomedicine and Prevention, University of Rome Tor Vergata, Rome, Italy.
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PO:04:061 | Higher prevalence of baseline comorbidities in patients developing difficult to treat psoriatic arthritis Mario Ferraioli1, Michelina Turri1, Eneida Çela1, Mauro Fatica1, Paola Conigliaro1, Elisabetta Greco1, Alberto Bergamini1, Maria Sole Chimenti1. | 1Rheumatology, Allergology and Clinical Immunology, Department of Systems Medicine, University of Rome, Tor Vergata, Rome, Italy.
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CO:09:6 | Risk of disease flare during pregnancy and postpartum in inflammatory arthritis: association with therapy discontinuation in the prospective P-RHEUM.it study Dina Zucchi1, Chiara Tani1, Francesca Crisafulli2, Alessia Gatti2, Maria Gerosa3, Cecilia Chighizola3, Melissa Padovan4, Salvatore D'Angelo5, Florenzo Iannone6, Maria Sole Chimenti7, Claudia Lomater8, Francesca Serale9, Veronique Ramoni10, Oscar Epis11, Bernd Raffeiner12, Ariela Hoxha13, Andrea Doria14, Leonardo Santo15, Valentina Canti16, Francesca Bellisai17, Giovanna Cuomo18, on behalf of the P-Rheumit Investigators19, Greta Carrara20, Cristina Di Nicola20, Davide Rozza20, Carlo Alberto Scirè20, Maria Chiara Gerardi11, Angela Tincani2, Laura Andreoli2, Marta Mosca1. | 1Rheumatology Unit, University of Pisa and Azienda Ospedaliero Universitaria Pisana; 2Rheumatology and Clinical Immunology Unit, ASST Spedali Civili, Brescia; 3Clinical Rheumatology Division, ASST Gaetano Pini-CTO and University of Milano; 4Rheumatology Unit, Azienda Ospedaliero-Universitaria S. Anna and University of Ferrara; 5Rheumatology Department of Lucania - San Carlo Hospital, Potenza; 6Rheumatology Unit, DiMePRE-J, University of Bari; 7Department of Systems Medicine, Rheumatology, Allergology and Clinical Immunology, University of Rome-Tor Vergata, Roma; 8Torino Academic Rheumatology Center, A.O. Mauriziano di Torino, University of Torino; 9Rheumatology Unit, ASL CN1 Cuneo; 10Internal Medicine Department, ASST Lodi - Ospedale Maggiore di Lodi; 11Division of Rheumatology, Multispecialist Medical Department, Grande Ospedale Metropolitano Niguarda, Milano; 12Department of Rheumatology, Central Hospital of Bolzano SABES-ASDAA, Bolzano; 13General Medicine and Thrombosis and Hemorrhagic Unit, Department of Medicine, University of Padova; 14Rheumatology Unit, Department of Medicine, University of Padova; 15Rheumatology Unit, Mons. Dimiccoli Hospital, Barletta; 16Division of Immunology, Transplantation and Infectious Diseases, IRCCS Ospedale San Raffaele, Milano; 17Rheumatology Unit, Department of Medicine, Surgery and Neurosciences, University of Siena; 18Precision Medicine Department, University of Campania L. Vanvitelli, Napoli; 19The Italian Society for Rheumatology; 20Epidemiology Research Unit of the Italian Society for Rheumatology, Milano, Italy
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PO:32:178 | Effectiveness of oral anticoagulants in precapillary pulmonary hypertension associated with systemic sclerosis: a EUSTAR cohort study Nicola Farina1, Silvia Bellando-Randone1, Hilde Jenssen-Bjørkekjær2, David Launay3, Patricia Carreira4, Paolo Airò5, Serena Guiducci1, Dilia Giuggioli6, Gabriela Riemekasten7, Carmen-Pilar Simeón Aznar8, Christina Bergmann9, Elise Siegart10, Ivan Castellví11, Lesley Ann Saketkoo12, Jeska De Vries-Bouwstra13, Philipp Klemm14, Ulf Müller-Ladner14, Alexandra Balbir-Gurman15, Vanessa Smith16, Florenzo Iannone17, Luca Idolazzi18, Christopher Denton19, Edoardo Rosato20, Britta Maurer1, Yannick Allanore1, Yoshiya Tanaka1, Elisabetta Zanatta1, Oliver Distler1, Marco Matucci-Cerinic1, Cosimo Bruni1 | 1Department of Experimental and Clinical Medicine, Scleroderma Unit, Division of Rheumatology, University of Florence, Az Firenze, Italy; 2Department of Rheumatology, Hospital of Southern Norway Kristiansand, Norway; 3National Reference Center for Pulmonary Arterial Hypertension Pulmotension Lille, France; 4Hospital Universitario 12 de Octubre, Rheumatology Department Madrid Spain; 5ASST Spedali Civili of Brescia, University of Brescia, Rheumatology and Clinical Immunology Unit Brescia, Italy; 6Scleroderma Unit, Rheumatology Unit, University Hospital of Modena and Reggio Emilia Modena, Italy; 7Universitätsklinikum Schleswig-Holstein, Klinik für Rheumatologie und klinische Immunologie Lübeck Germany; 8Hospital Universitario Vall d'Hebron, Department of Internal Medicine, Systemic Autoimmune Diseases Unit Barcelona Spain; 9University Hospital Erlangen, Department Internal Medicine 3 Erlangen Germany; 10Charité University Hospital, Department of Rheumatology Berlin Germany; 11Hospital de la Santa Creu i Sant Pau Baercelona Spain; 12New Orleans Scleroderma and Sarcoidosis Patient Care and Research Center New Orleans, USA; 13Leiden University Medical Center, Department of Rheumatology Leiden, The Netherlands; 14JLU Giessen, Campus Kerckhoff, Department of Rheumatology and Clinical Immunology Center Bad Nauheim Germany; 15Rambam Health Care Campus, Rheumatology Institute Haifa, Israel; 16University of Ghent, Department of Rheumatology Ghent, Belgium; 17Rheumatology DiMePReJ, University of Bari, School of Medicine Bari, Italy; 18University of Verona, Section of Rheumatology, Department of Medicine Verona, Italy; 19Royal Free London and University College London Medical School, Centre for Rheumatology London, United Kingdom; 20Sapienza University of Rome, Department of Translational and Precision Medicine Azienda Ospedaliero-Universitaria Policl Roma, Italy
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PO:06:094 | Exploring the relationship between inflammation and collagen deposition in synovial tissue and clinical outcomes in active arthritis: insights from a monocentric pilot study Dario Bruno1, Barbara Tolusso1, Daniela Renna1, Mohamed Hegazi2, Fabio Pasqualini2, Marta Caprioli1, Giacomo Maria Guidelli1, Tommaso Hubert3, Nicoletta Luciano1|3, Marzia Monferini3, Natasa Isailovic3, Fabio Grizzi2|3, Salvatorelorenzo Renne3, Costantino Pitzalis1|3|4, Elisa Gremese1|3. | 1Rheumatology and Clinical Immunology, IRCCS Humanitas Research Hospital, Rozzano (MI); 2Department of Immunology and Inflammation, IRCCS Humanitas Research Hospital, Milano; 3Department of Biomedical Sciences, Humanitas University, Rozzano (MI), Italy; 4Centre for Experimental Medicine and Rheumatology, Queen Mary University of London, London, UK
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PO:14:193 | Dapirolizumab Pegol Demonstrated Significant Improvement in Systemic Lupus Erythematosus Disease Activity: Efficacy and Safety Results of a Phase 3 Trial Megan EB Clowse1, Marta Mosca2, David A Isenberg3, Joan T Merrill4, Thomas Dörner5, Michelle Petri6, Edward M Vital7|8, Eric F Morand9, Teri Jimenez10, Stephen Brookes11, Janine Gaiha-Rohrbach12, Christophe Martin13, Annette Nelde14, Christian Stach15 | 1Duke University - Division of Rheumatology and Immunology Durham, USA; 2University of Pisa - Rheumatology Unit, Department of Clinical and Experimental Medicine Pisa, Italy; 3University College London - Department of Ageing, Rheumatology and Regenerative Medicine, Division of Medicine London, United Kingdom; 4Oklahoma Medical Research Foundation Oklahoma City, USA; 5Charité Universitätsmedizin Berlin - Department of Medicine/Rheumatology and Clinical Immunology Berlin Germany; 6Johns Hopkins University School of Medicine Baltimore, USA; 7University of Leeds - Leeds Institute of Rheumatic and Musculoskeletal Medicine Leeds, United Kingdom; 8Leeds Teaching Hospitals NHS Trust - NIHR Leeds Biomedical Research Centre Leeds, United Kingdom; 9Monash University - Centre for Inflammatory Diseases Melbourne, Australia; 10UCB Raleigh, USA; 11Biogen Maidenhead, United Kingdom; 12Biogen Cambridge, USA; 13UCB Slough, United Kingdom; 14Biogen Baar, Switzerland; 15UCB Monheim am Rhein, Germany
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PO:19:279 | Predictors of proteinuria, amyloidosis and kidney failure in familial Mediterranean fever: data from the International AIDA Network Registry Jessica Sbalchiero1, Antonio Vitale1, Valeria Caggiano1, Abdurrahman Tufan2, Ezgi Batu3, Gaafar Ragab4, Seza Ozen3, Jurgen Sota1, Carla Gaggiano1, Ali Sahin5, Petros Sfikakis6, Francesca Li Gobbi7, Giacomo Emmi8, Jose Rodriguez9, Piero Ruscitti10, Paolo Sfriso11, Ewa Szewczyk12, Giuseppe Lopalco13, Alberto Balistreri14, Claudia Fabiani15, Bruno Frediani1, Luca Cantarini1 | 1Department of Medical Sciences, Surgery and Neurosciences, University of Siena, Siena, Italy; 2Department of Internal Medicine, Division of Rheumatology, Gazi University Hospital Ankara, Turkey; 3Division of Pediatric Rheumatology, Department of Pediatrics, Hacettepe University School of Medicine Ankara, Turkey; 4Internal Medicine Department, Rheumatology and Clinical Immunology Unit, Faculty of Medicine, Cairo University Giza, Egypt; 5Division of Rheumatology, Department of Internal Medicine, Sivas Cumhuriyet University Medical Faculty Sivas, Turkey; 6Joint Academic Rheumatology Program, Medical School, National and Kapodistrian University of Athens Athens, Greece; 7Rheumatology Unit, Hospital S. Giovanni di Dio, Azienda USL-Toscana Centro Florence, Italy; 8Clinical Medicine and Rheumatology Unit, Cattinara University Hospital Trieste, Italy; 9Department of Autoimmune Diseases, Institut Investigacions Biomediques August Pi I Sunyer, University of Barcelona Barcelona Spain; 10Rheumatology Unit, Department of Biotechnological and Applied Clinical Sciences, University of L'Aquila, L'Aquila, Italy; 11Rheumatology Unit, Department of Medicine, University of Padua Padua, Italy; 127Department of Internal Medicine, Pneumonology, Allergology, Clinical Immunology and Rare Diseases, Military Institute o Warsaw, Poland; 13Department of Precision and Regenerative Medicine and Ionian Area DiMePRe-J Policlinic Hospital, University of Bari Bari, Italy; 14Bioengineering and Biomedical Data Science Lab, Department of Medical Biotechnologies, University of Siena Siena, Italy; 15Ophthalmology Unit, Department of Medicine, Surgery and Neurosciences, University of Siena Siena, Italy
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CO:09:2 | Mapping Emotional Function in Fibromyalgia: Integrating Alexithymia, Pain Catastrophizing and Self-Compassion Francesca Trunfio1, Damiano Currado1|2, Rosa Bruni3, Barbara Biticchi1, Francesca Saracino1, Erika Corberi1, Ludovica Lamberti1, Annalisa Marino1|2, Lyubomyra Kun1, Leonardo Frasca'1, Sebastiano Lorusso1, Marta Vomero2, Onorina Berardicurti1|2, Roberto Giacomelli1|2, Luca Navarini1|2 | 1Rheumatology and Clinical Immunology, Department of Medicine, University of Rome Campus Biomedico, School of Medicine, Rome, Italy; 2Clinical and Research Section of Rheumatology and Clinical Immunology, Fondazione Policlinico Campus Biomedico, Rome, Italy; 3Psychiatrist, Psychotherapist, certified Teacher Mindful Self-Compassion Program, contract Professor at University Campu Rome, Italy
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PO:35:234 | Sustained Vasculitis Quiescence and CS Reduction with Mepolizumab 100 mg Francesca Mascia1, Angelo Fassio2, Marco Zurlo1, Davide Chesini3, Francesco Pollastri2, Giovanni Adami2, Davide Gatti4, Maurizio Rossini4, Matteo Maule5, Gianentrico Senna1, Marco Caminati1 | 1University of Verona - Allergology and Clinical Immunology Verona, Italy; 2Policlinico G. B. Rossi - Rheumatology Verona, Italy; 3University of Verona - Faculty of Medicine and Surgery Verona, Italy; 4University of Verona - Rheumatology Verona, Italy; 5Policlinico G. B. Rossi - Allergology and Clinical Immunology Verona, Italy
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PO:18:268 | Voclosporin as a Steroid-Sparing Agent in Lupus Nephritis Complicated by Central Serous Chorioretinopathy: A Case Report Irene Genovali1|2, Sebastiano Lorusso2, Damiano Currado1|2, Letizia Pia Di Corcia1, Ludovica Lamberti1, Annalisa Marino2, Antonio Orlando1, Maria Quadrini1, Marta Vadacca2, Marta Vomero1, Luca Navarini1|2, Roberto Giacomelli1|2 | 1Rheumatology and Clinical Immunology, Department of Medicine, University of Rome Campus Biomedico, School of Medicine Rome, Italy; 2Clinical and Research Section of Rheumatology and Clinical Immunology Fondazione Policlinico Campus Biomedico Rome, Italy
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PO:33:202 | Assessment of Retinal Arteriolar Wall-to-Lumen Ratio and Renal Resistive Index in patients with Systemic Sclerosis Eleonora Pazzi1|2, Elda Piovani1|2, Claudia Barison1|2, Liala Moschetti1|2, Eleonora Pedretti1|2, Mariagrazia Lazzaroni1|2, Carolina De Ciuceis3, Claudia Agabiti-Rosei3, Giacomo Buso3|4, Paolo Baggi3, Claudia Rossini3, Cristina Bevacqua3, Maria Lorenza Muiesan3, Ilaria Cavazzana1, Franco Franceschini1, Paolo Airò2 | 1Rheumatology and Clinical Immunology, ASST Spedali Civili of Brescia, University of Brescia, Brescia, Italy; 2Scleroderma Unit, ASST Spedali Civili of Brescia, Brescia, Italy; 3Department of Clinical and Experimental Sciences, Division of Internal Medicine, ASST Spedali Civili of Brescia, Univers Brescia, Italy; 4University of Lausanne, Lausanne Switzerland
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CO:10:2 | Common variable immunodeficiency patients complicated by autoimmune and inflammatory rheumatic manifestations reveal high frequency of genetic variants potentially linked to inborn errors of immunity Paolo Semeraro1, Micol Frassi1, Silvia Clara Giliani2, Franco Franceschini1, Paolo Airò1. | 1Rheumatology and Clinical Immunology Unit, ERN ReCONNET, ASST Spedali Civili of Brescia and University of Brescia; 2Medical Genetic Laboratory, ASST Spedali Civili of Brescia and University of Brescia, Italy
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PO:26:088 | Rheumatologic immune-related adverse events from immune checkpoint inhibitors: a monocentric retrospective study Giulio Fraticelli1|2, Nicola Farina1|2, Alessandro Tomelleri1|2, Marco Matucci Cerinic1|2, Corrado Campochiaro1|2, Lorenzo Dagna1|2. | 1Unit of Immunology, Rheumatology, Allergy and Rare Diseases UNIRAR, IRCCS San Raffaele Hospital, Milano, Italy; 2Inflammation, Fibrosis and Ageing Initiative INFLAGE, IRCCS San Raffaele Hospital, Milano, Italy.
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CO:07:4 | Clinical and psychosocial domains in fibromyalgia: a multidimensional questionnaire approach for personalized management. Results from an Italian monocentric study Eleonora Pedretti1, Francesca Regola1, Giulia Fontana1|2, Giulia Voltarel1|2, Michela Riolfo1|2, Anna Scalvini1, Ilaria Cavazzana1|2, Franco Franceschini1|2, Roberto Gorla1. | 1Rheumatology and Clinical Immunology Unit - ERN ReCONNET, ASST Spedali Civili of Brescia; 2Department of Clinical and Experimental Sciences, University of Brescia, Italy
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PO:07:108 | Achievement of Treatment Targets and Maintenance of Response with Upadacitinib in Patients with Moderate-to-Severe Rheumatoid Arthritis in a Real-world Setting: Final 2-year Outcomes from the UPHOLD Study Enrico Marchetta1, Andrew Östör2|8, Eugen Feist3, Prodromos Sidiropoulos4, Jérôme Avouac5, Martin Rebella6|7, Rajaie Namas9, Erin Mcdearmon Blondell10, Ivan Lagunes10, Tianming Gao10, Tim Shaw10, Suzan Attar11 | 1AbbVie Srl Roma, Italy; 2Monash University and Emeritus Research, Melbourne, Victoria, Melbourne, Australia; 3Helios Department of Rheumatology and Clinical Immunology, Vogelsang-Gommern, Vogelsang Gommern, Germany; 4Faculty of Medicine, University of Crete, Heraklion, Heraklion, Greece; 5Service de Rhumatologie, Hôpital Cochin, AP HP Centre Université Paris Cité, Parigi, France; 6Departamento de Medicina, Facultad de Medicina, Universidad de la República, Montevideo, Montevideo, Uruguay; 7Unidad de Enfermedades Autoinmunes Sistémicas, MUCAM, Montevideo, Montevideo, Uruguay; 8Australian National University, Camberra, Australia; 9Medical Subspecialties Institute, Division of Rheumatology, Cleveland Clinic Abu Dhabi, United Arab Emirates; 10AbbVie Inc., North Chicago, Illinois, United States of America Chicago, USA; 11King Abdulaziz University, Jeddah, Saudi Arabia
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PO:31:172 | Age and timing of onset of Raynaud's phenomenon and first non-Raynaud sign/symptom as prognostic factors in systemic sclerosis: a retrospective analysis from the systemic sclerosis progression investigation registry of the Italian Society for Rheumatology Silvia Peretti1, Cosimo Bruni2, Silvia Laura Bosello3, Fabio Cacciapaglia4-5, Corrado Campochiaro6-7, Veronica Codullo8, Lorenzo Dagna6-7, Rossella De Angelis9, Giacomo De Luca6-7, Dilia Giuggioli10, Serena Guiducci1, Florenzo Iannone4, Francesca Ingegnoli11, Valeria Riccieri12, Marco Matucci Cerinic6-7, Clodoveo Ferri10-13, Silvia Bellando Randone1. | 1Division of Rheumatology, Scleroderma Unit, Department of Experimental and Clinical Medicine, University of Florence, AO, Firenze, Italy; 2Division of Rheumatology, University Hospital Zurich, University of Zurich, Zurich, Switzerland; 3Rheumatology Division, Catholic University of the Sacred Heart, Fondazione Policlinico Universitario A. Gemelli- IRCCS, Roma, Italy; 4Rheumatology Unit, Department of Precision and Regenerative Medicine-Ionian Area, University of Bari Aldo Moro, Bari, Italy; 5Reumatology Service, Internal Medicine Unit F.Miulli General Hospital, Acquaviva delle Fonti -Department of Medicine a, Bari, Italy; 6Unit of Immunology, Rheumatology, Allergy and Rare Diseases UnIRAR, Inflammation, Fibrosis and Ageing initiative INFL, Milano, Italy; 7Vita-Salute San Raffaele University, Milano, Italy; 8Department of Internal Medicine and Therapeutics, Università di Pavia, Italy; Division of Rheumatology, Fondazione IRCCS, Pavia, Italy; 9Rheumatology Unit, Department of Clinical and Molecular Sciences, Polytechnic University of Marche, Ancona, Italy; 10Rheumatology Unit, School of Medicine, University of Modena and Reggio Emilia, Modena, Italy; 11Division of Clinical Rheumatology, ASST Pini, Dept. of Clinical Sciences and Community Health, Research Center for Adul, Milano, Italy; 12Department of Rheumatology, Sapienza University of Rome, Roma, Italy; 13Rheumatology Clinic Madonna dello Scoglio Crotonei, Crotone, Italy.
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CO:07:5 | Enhanced fibroblast signatures in females with early rheumatoid arthritis highlights a potential basis for poorer treatment outcomes Benedetta Monosi1, James Perera2, Alessandra Nerviani2|3, Maria Sole Chimenti1, Felice Rivellese2|3, Costantino Pitzalis2|3|4. | 1Rheumatology, Allergology and Clinical Immunology, Department of Systems Medicine, University of Rome Tor Vergata, Rome, Italy; 2Centre for Experimental Medicine and Rheumatology, William Harvey Research Institute, Queen Mary University of London, London, UK; 3Barts Health NHS Trust and Barts Biomedical Research Centre, National Institute for Health and Care Research, London, UK; 4Department of Biomedical Sciences Humanitas University and IRCCS Humanitas Research Hospital, Milano, Italy
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PO:32:185 | Deep-learning analysis of high-resolution computed tomography images predicts progression and mortality in systemic sclerosis related interstitial lung disease Valentina Boni1, Rosa D'Abronzo2, Piergiacomo Cerasuolo1, Lucio Calandriello2, Giuseppe Cicchetti2, Gerlando Natalello1, Bruno Iovene5, Francesco Varone5, Giacomo Sgalla5, Luca Richeldi5, Anna Rita Larici2|4, Maria Antonietta D'Agostino1|3, Silvia Laura Bosello1|3, Enrico De Lorenzis1. | 1Division of Rheumatology and Clinical Immunology Catholic Univeristy of the Sacred Heart, Rome, Italy; 2Department of Diagnostic Imaging, Oncological Radiotherapy and Hematology, Diagnostic Imaging Area, Catholic University, Rome, Italy; 3Department of Geriatric and Orthopaedic Sciences, Catholic Univeristy of the Sacred Heart, Rome, Italy; 4Department of Radiological and Hematological Sciences, Section of Radiology, Catholic Univeristy of the Sacred Heart, Rome, Italy; 5Division of Pulmonary Medicine, Catholic University of the Sacred Heart, Roma, Italy.
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CO:05:4 | Natural language processing reveals demographic features, comorbidities, and clinical domains to predict treatment longevity of b/tsDMARDs in psoriatic arthritis Antonio Tonutti1|2, Pierandrea Morandini3, Cosimo Faeti3, Nicoletta Luciano1|2, Saverio D'Amico3, Victor Savevski3, Carlo Selmi1|2 | 1Department of Biomedical Sciences, Humanitas University Pieve Emanuele, Milan, Italy; 2Rheumatology and Clinical Immunology, IRCCS Humanitas Research Hospital Rozzano, Milan, Italy; 3Artificial Intelligence Unit, IRCCS Humanitas Research Hospital Rozzano, Milan, Italy
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PO:24:064 | IPF vs CTD-ILD: Survival and Lung Function from an Italian Real-World Cohort Marco Fornaro1, Donato Lacedonia2, Lorenzo Cavagna3, Paolo Airò4, Marco Sebastiani5, Gianluca Sambataro6, Fabio Cacciapaglia7, Angelica Napoletano1, Cosimo De Pace2, Pasquale Tondo2, Giulia Scioscia2, Eleonora Pedretti4, Maria Grazia Lazzaroni4, Carlo Vancheri8, Andreina Manfredi9, Lorenzo Binchessi3, Rocco Capece3, Michele De Ceglie10, Massimo Giotta11, Florenzo Iannone1 | 1Unit of Rheumatology, Department of Precision and Regenerative Medicine - Area Jonica DiMePRe-J, University of Bari, Bari, Italy; 2Department of Medical and Surgical Sciences, University of Foggia Foggia, Italy; 3Department of Internal Medicine and Therapeutics, University of Pavia, Division of Rheumatology, Fondazione IRCCS, Pavia, Italy; 4Rheumatology and Clinical Immunology Unit, Department of Clinical and Experimental Sciences, ASST Spedali Civili Brescia, Italy; 5Rheumatology Unit, AUSL Piacenza, Department of Medicine and Surgery, University of Parma, Parma, Italy; 6Department of Medicine and Surgery, University of Enna Kore, Enna, Italy; 7Rheumatology Service, F. Miulli Hospital and Department of Medicine and Surgery, LUM University, Casamassima, Italy; 8Department of Clinical and Experimental Medicine, Regional Referral Center for Rare Lung Diseases, Catania, Italy; 9Rheumatology Unit, IRCCS Santa Maria Nuova Reggio Emilia, University of Modena, Modena, Italy; 10DIM, Interdisciplinary Department of Medicine, Section of Diagnostic Imaging, University of Bari, Bari, Italy; 11Health Prevention Department, Local Health Authority of Brindisi, Brindisi, Italy
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PO:15:209 | Attainment of remission or lupus low disease activity state in single center Lupus Clinic Paola Tedoldi1|2, Silvia Ebe Lucia Della Pina1|2, Claudia Barison1|2, Chiara Orlandi1|2, Cecilia Nalli1, Micaela Fredi2, Ilaria Cavazzana1|2, Franco Franceschini1|2 | 1Rheumatology and Clinical Immunology Unit- ERN ReCONNET, ASST Spedali Civili of Brescia Brescia, Italy; 2Department of Clinical and Experimental Sciences, University of Brescia Brescia, Italy
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PO:26:096 | From free text to diagnosis: a Natural Language Processing approach for identifying rheumatoid and psoriatic arthritis in the Emergency Department Antonio Tonutti1|2, Pierandrea Morandini3, Cosimo Faeti3, Nicoletta Luciano1|2, Saverio D'Amico3, Antonio Voza1|4, Victor Savevski3, Carlo Selmi1|2 | 1Department of Biomedical Sciences, Humanitas University Pieve Emanuele, Milan, Italy; 2Rheumatology and Clinical Immunology, IRCCS Humanitas Research Hospital Rozzano, Milan, Italy; 3Artificial Intelligence Unit, IRCCS Humanitas Research Hospital Rozzano, Milan, Italy; 4Emergency Department, IRCCS Humanitas Research Hospital Rozzano, Milan, Italy
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PO:03:039 | Extraintestinal manifestations of enteropathic arthritis vary in relation to inflammatory bowel disease behaviour, localization, and extent Bernardo D'Onofrio1, Nicoletta Luciano2|3, Simone Parisi1, Maria Chiara Ditto1, Cristina Bezzio2|4, Enrico Fusaro1, Alessandro Armuzzi2|4, Carlo Selmi2|3 | 1Division of Rheumatology, AOU Città della Salute e della Scienza, Torino, Italy; 2Department of Biomedical Sciences, Humanitas University, Pieve Emanuele, Italy; 3Rheumatology and Clinical Immunology, IRCCS Humanitas Research Hospital, Rozzano, Italy; 4Inflammatory Bowel Disease Unit, IRCCS Humanitas Research Hospital, Rozzano, Italy
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PO:26:087 | Rituximab versus glucocorticoids for IgG4-related disease: a European retrospective multi-center study of 167 patients Marco Lanzillotta1, Jens Vikse2, Elisabetta Goni3, Jasmin Mahajne1, Veronica Batani1, Lorenzo Dagna1, Emanuel Della-Torre1 | 1Unit of Immunology, Rheumatology, Allergy, and Rare Disease, IRCCS Ospedale san Raffaele Milano, Italy; 2Department of Rheumatology, Stavanger University Hospital, Stavanger, Norway; 3Department of Medicine II, University Hospital, Ludwig Maximilian University Munich, Munich Germany
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PO:28:116 | Glandular involvement in autoimmune diseases: a spectrum of differential diagnosis Francesca Petrillo1, Caterina Ricordi1, Caterina Tomassini1, Luca Cimino3, Giorgia Citriniti2, Fabio Brandolino2, Chiara Marvisi1, Carlo Salvarani1 | 1S.C. Reumatologia; 2S.C. Reumatologia; 3S.S.D. Immunologia Oculare, Università di Modena e Reggio Emilia, Arcispedale Santa Maria Nuova, Reggio Emilia, Italy
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