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PO:08:117 | Association between the use of oral contraceptives and the development of rheumatoid arthritis: a systematic review and meta-analysis Annalisa Marino1, Damiano Currado1|2, Onorina Berardicurti1|2, Marta Vomero2, Lyubomyra Kun1, Letizia Pia Di Corcia2, Erika Corberi2, Francesca Trunfio2, Francesca Saracino2, Ludovica Lamberti2, Leonardo Frasca2, Angelo Battista3, Marta Alfano4, Silvia Schiavone5, Roberto Giacomelli1|2, Luca Navarini1|2. | 1Clinical and Research Section of Rheumatology and Clinical Immunology, Fondazione Campus Bio-Medico, Roma; 2Rheumatology and Clinical Immunology, Department of Medicine, University of Rome Campus Biomedico, School of Medicine, Roma; 3Department of Maternal Science, Paediatric Emergency Service, Sapienza University of Rome, Roma; 4Department of Experimental Medicine, Sapienza University of Rome, Roma; 5Department of Orthopaedics and Traumatology, Policlinico Tor Vergata Foundation, Roma, Italy
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PO:31:167 | Increased M2 pro-fibrotic marker expression in circulating monocytes and cultured monocyte-derived macrophages in systemic sclerosis patients with progressive interstitial lung disease Vanessa Smith1|2, Stefano Soldano3, Rosanna Campitiello3|5, Emanuele Gotelli3|4, Paola Montagna3, Elvis Hysa3|5, Tamara Vojinovic3|4, Carmen Pizzorni3|4, Sabrina Paolino3|4, Alberto Sulli3|4, Maurizio Cutolo3|4. | 1Department of Internal Medicine and Department of Rheumatology, Ghent University Hospital, Ghent, Belgium; 2Unit for Molecular Immunology and Inflammation, VIB Inflammation Research Centre, Ghent, Belgium; 3Laboratory of Experimental Rheumatology and Academic Division of Clinical Rheumatology, Department of Internal Medicine, Genova, Italy; 4IRCCS Ospedale Policlinico San Martino, Genova, Italy; 5Department of Experimental Medicine DIMES, University of Genova, Genova, Italy.
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PO:32:176 | Outcomes of upfront combination vs monotherapy with rituximab or mycophenolate mofetil for systemic sclerosis interstitial lung disease: results from a European Scleroderma Trials and Research cohort study Devis Benfaremo1, Corrado Campochiaro2, Gábor Kumánovics3, Christina Bergmann4, Elisabetta Zanatta5, David Launay6, Serena Guiducci7, Mickael Martin8, Carolina De Souza Müller9, Carlomaurizio Montecucco10, Luc Mouthon11, Gabriella Szucs12, Kastriot Kastrati13, Marie-Elise Truchetet14, Madelon Vonk15, Francesco Del Galdo16, Marco Matucci-Cerinic2, Gianluca Moroncini1, Yannick Allanore17. | 1Department of Clinical and Molecular Sciences, Marche Polytechnic University, Marche University Hospital, Ancona, Italy; 2Vita-Salute San Raffaele University, San Raffaele Hospital, Milano, Italy; 3University of Pécs, Department Of Rheumatology And Immunology, Pécs, Hungary; 4University Hospital Erlangen, Department Internal Medicine 3, Erlangen, Germany; 5Padova University Hospital, Rheumatology Unit, Padova, Italy; 6Univ. Lille, Inserm, CHU Lille, Department of Internal Medicine and Clinical Immunology, Lille, France; 7University of Florence, Azienda Ospedaliera Universitaria Careggi, Firenze, Italy; 8Poitiers University Hospital, Department of Internal Medicine Poitiers France; 9Hospital de Clinicas da Universidade Federal do Parana Curitiba Brazil; 10Università di Pavia e IRCCS Fondazione Policlinico S. Matteo, Pavia, Italy; 11Hôpital Cochin, Department of Internal Medicine, Paris, France; 12University of Debrecen, Faculty of Medicine, Department of Rheumatology, Debrecen, Hungary; 13Medical University of Vienna, Department of Medicine III, Division of Rheumatology, Vienna, Austria; 14CHU de Bordeaux, Rheumatology department, Bordeaux, France; 15Radboudumc, Department of Rheumatology Nijmegen The Netherlands; 16Leeds Raynauds and Scleroderma Program, NIHR Biomedical Research Centre, Leeds, United Kingdom; 17Université Paris Cité, Cochin Hospital, Rheumatology Department, Paris, France.
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PO:02:016 | Real-world evidence of upadacitinib over two years in Italian patients with axial spondyloarthritis Mariagrazia Lorenzin1, Giacomo Cozzi1, Stefano Gentileschi2, Michele Maria Luchetti Gentiloni3, Antonio Carletto4, Maria Sole Chimenti5, Maria Manara6, Luca Quartuccio7, Rosario Foti8, Salvatore D'Angelo9, Ariela Hoxha10, Carlo Selmi11, Bernd Raffeiner12, Alessandro Giollo1, Alberto Cauli13, Carlo Salvarani14, Fabiola Atzeni15, Roberta Ramonda1, Sir Study Group Spa E Psa Antonio Spadaro16. | 1Rheumatology Unit, Department of Medicine DIMED, University of Padova, Padova, Italy; 2Rheumatology Unit, Department of Medicine, Surgery and Neurosciences, University of Siena, Siena, Italy; 3Clinica Medica, Ospedali Riuniti Ancona University Hospital, Ancona; Department of Clinical and Molecular Sciences, Ancona, Italy; 4Rheumatology Unit, Department of Medicine, AOUI University of Verona, Verona, Italy; 5Rheumatology, allergology and clinical Immunology, Department of Systems Medicine, University of Rome Tor Vergata, Roma, Italy; 6Humanitas San Pio X, Milano, Italy; 7University of Udine, Academic Hospital Santa Maria della Misericordia, Udine, Italy; 8Rheumatology Unit, A.O.U. Policlinico S. Marco, Catania, Italy; 9Rheumatology Department of Lucania, San Carlo Hospital of Potenza and Madonna delle Grazie Hospital of Matera, Potenza, Italy; 10Internal Medicine Unit, Thrombotic and Hemorrhagic Center, Department of Medicine-DIMED, University of Padua, Padova, Italy; 11Department of Rheumatology and Clinical Immunology, IRCCS Humanitas Research Hospital, Rozzano, Milano, Italy; 12Department of Rheumatology, Teaching Hospital of the Paracelsius Medical Hospital of Bolzano ASAA-SABES, Bolzano, Italy; 13Rheumatology Unit, Department of Medical Sciences, AOU and University of Cagliari, Monserrato, Cagliari, Italy; 14Department of Rheumatology, Azienda USL-IRCCS di Reggio Emilia and Università di Modena and Reggio Emilia, Reggio Emilia, Italy; 15Rheumatology Unit, University of Messina, Messina, Italy; 16Società Italiana di Reumatologia, Milano, Italy.
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PO:06:094 | Exploring the relationship between inflammation and collagen deposition in synovial tissue and clinical outcomes in active arthritis: insights from a monocentric pilot study Dario Bruno1, Barbara Tolusso1, Daniela Renna1, Mohamed Hegazi2, Fabio Pasqualini2, Marta Caprioli1, Giacomo Maria Guidelli1, Tommaso Hubert3, Nicoletta Luciano1|3, Marzia Monferini3, Natasa Isailovic3, Fabio Grizzi2|3, Salvatorelorenzo Renne3, Costantino Pitzalis1|3|4, Elisa Gremese1|3. | 1Rheumatology and Clinical Immunology, IRCCS Humanitas Research Hospital, Rozzano (MI); 2Department of Immunology and Inflammation, IRCCS Humanitas Research Hospital, Milano; 3Department of Biomedical Sciences, Humanitas University, Rozzano (MI), Italy; 4Centre for Experimental Medicine and Rheumatology, Queen Mary University of London, London, UK
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PO:31:175 | Characterizing gastrointestinal involvement in systemic sclerosis: insights from the national systemic sclerosis progression investigation registry of the Italian Society of Rheumatology Francesco Bonomi1, Cosimo Bruni1|2, Silvia Laura Bosello3, Fabio Cacciapaglia4|5, Corrado Campochiaro6, Roberto Caporali7, Veronica Codullo8, Maria Antonietta D'Agostino3, Lorenzo Dagna6, Rossella De Angelis9, Giacomo De Luca6, Dilia Giuggioli10, Serena Guiducci1, Florenzo Iannone4, Francesca Ingegnoli7, Carlomaurizio Montecucco8, Valeria Riccieri11, Clodoveo Ferri10, Marco Matucci Cerinic6, Silvia Bellando Randone1. | 1Scleroderma Unit, Division of Rheumatology AOUC, and Department of Experimental and Clinical Medicine, Uni. of Florence, Firenze, Italy; 2Department of Rheumatology, University Hospital Zurich, University of Zurich Zurigo Switzerland; 3UOC of Rheumatology and Clinical Immunology, Catholic University of the Sacred Heart, Fondazione Policlinico A. Gemelli, Roma, Italy; 4Rheumatology Unit, Department of Emergency Surgery and Organ Transplantations, University of Bari, Bari, Italy; 5Rheumatology Service, F. Miulli General Hospital - Department of Medicine and Surgery, LUM 'G. De Gennaro', Casamassima, Italy; 6Unit of Immunology, Rheumatology, Allergy and Rare Diseases and Inflammation, fibrosis and ageing initiative, UniSR, Milano, Italy; 7Division of Clinical Rheumatology, ASST Pini and Università degli studi di Milano, Milano, Italy; 8Department of Rheumatology, Policlinico San Matteo, Pavia, Italy; 9Rheumatology Unit, Department of Clinical and Molecular Sciences, Polytechnic University of Marche, Ancona, Italy; 10Rheumatology Unit, School of Medicine, University of Modena and Reggio Emilia, Modena, Italy; 11Department of Rheumatology, Sapienza University of Rome, Roma, Italy.
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PO:19:279 | Predictors of proteinuria, amyloidosis and kidney failure in familial Mediterranean fever: data from the International AIDA Network Registry Jessica Sbalchiero1, Antonio Vitale1, Valeria Caggiano1, Abdurrahman Tufan2, Ezgi Batu3, Gaafar Ragab4, Seza Ozen3, Jurgen Sota1, Carla Gaggiano1, Ali Sahin5, Petros Sfikakis6, Francesca Li Gobbi7, Giacomo Emmi8, Jose Rodriguez9, Piero Ruscitti10, Paolo Sfriso11, Ewa Szewczyk12, Giuseppe Lopalco13, Alberto Balistreri14, Claudia Fabiani15, Bruno Frediani1, Luca Cantarini1 | 1Department of Medical Sciences, Surgery and Neurosciences, University of Siena, Siena, Italy; 2Department of Internal Medicine, Division of Rheumatology, Gazi University Hospital Ankara, Turkey; 3Division of Pediatric Rheumatology, Department of Pediatrics, Hacettepe University School of Medicine Ankara, Turkey; 4Internal Medicine Department, Rheumatology and Clinical Immunology Unit, Faculty of Medicine, Cairo University Giza, Egypt; 5Division of Rheumatology, Department of Internal Medicine, Sivas Cumhuriyet University Medical Faculty Sivas, Turkey; 6Joint Academic Rheumatology Program, Medical School, National and Kapodistrian University of Athens Athens, Greece; 7Rheumatology Unit, Hospital S. Giovanni di Dio, Azienda USL-Toscana Centro Florence, Italy; 8Clinical Medicine and Rheumatology Unit, Cattinara University Hospital Trieste, Italy; 9Department of Autoimmune Diseases, Institut Investigacions Biomediques August Pi I Sunyer, University of Barcelona Barcelona Spain; 10Rheumatology Unit, Department of Biotechnological and Applied Clinical Sciences, University of L'Aquila, L'Aquila, Italy; 11Rheumatology Unit, Department of Medicine, University of Padua Padua, Italy; 127Department of Internal Medicine, Pneumonology, Allergology, Clinical Immunology and Rare Diseases, Military Institute o Warsaw, Poland; 13Department of Precision and Regenerative Medicine and Ionian Area DiMePRe-J Policlinic Hospital, University of Bari Bari, Italy; 14Bioengineering and Biomedical Data Science Lab, Department of Medical Biotechnologies, University of Siena Siena, Italy; 15Ophthalmology Unit, Department of Medicine, Surgery and Neurosciences, University of Siena Siena, Italy
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PO:19:286 | Genetic testing reveals an unexpected case of mevalonate kinase deficiency in a 37-year-old patient with AA renal amyloidosis and good response to colchicine Francesca Crisafulli1, Paolo Airò2, Federica Mescia3, Gianmarco Lugli3, Gianfranco Savoldi4, Claudia Izzi3|5, Federico Alberici3, Marco Cattalini6, Franco Franceschini1, Micol Frassi2. | 1Rheumatology and Clinical Immunology Unit, ASST Spedali Civili and University of Brescia, Brescia, Italy; 2Rheumatology and Clinical Immunology Unit, ASST Spedali Civili of Brescia, Brescia, Italy; 3U.O Nefrologia, ASST Spedali Civili di Brescia e Università degli Studi di Brescia, Brescia, Italy; 4Medical genetics Laboratory, Laboratory Department ASST Spedali Civili di Brescia, Brescia, Italy; 5Struttura Complessa di Genetica Clinica, ASST Spedali Civili di Brescia, Brescia, Italy; 6Pediatrics Clinic, University of Brescia and ASST Spedali Civili of Brescia, Brescia, Italy.
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CO:09:2 | Mapping Emotional Function in Fibromyalgia: Integrating Alexithymia, Pain Catastrophizing and Self-Compassion Francesca Trunfio1, Damiano Currado1|2, Rosa Bruni3, Barbara Biticchi1, Francesca Saracino1, Erika Corberi1, Ludovica Lamberti1, Annalisa Marino1|2, Lyubomyra Kun1, Leonardo Frasca'1, Sebastiano Lorusso1, Marta Vomero2, Onorina Berardicurti1|2, Roberto Giacomelli1|2, Luca Navarini1|2 | 1Rheumatology and Clinical Immunology, Department of Medicine, University of Rome Campus Biomedico, School of Medicine, Rome, Italy; 2Clinical and Research Section of Rheumatology and Clinical Immunology, Fondazione Policlinico Campus Biomedico, Rome, Italy; 3Psychiatrist, Psychotherapist, certified Teacher Mindful Self-Compassion Program, contract Professor at University Campu Rome, Italy
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PO:35:234 | Sustained Vasculitis Quiescence and CS Reduction with Mepolizumab 100 mg Francesca Mascia1, Angelo Fassio2, Marco Zurlo1, Davide Chesini3, Francesco Pollastri2, Giovanni Adami2, Davide Gatti4, Maurizio Rossini4, Matteo Maule5, Gianentrico Senna1, Marco Caminati1 | 1University of Verona - Allergology and Clinical Immunology Verona, Italy; 2Policlinico G. B. Rossi - Rheumatology Verona, Italy; 3University of Verona - Faculty of Medicine and Surgery Verona, Italy; 4University of Verona - Rheumatology Verona, Italy; 5Policlinico G. B. Rossi - Allergology and Clinical Immunology Verona, Italy
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PO:18:268 | Voclosporin as a Steroid-Sparing Agent in Lupus Nephritis Complicated by Central Serous Chorioretinopathy: A Case Report Irene Genovali1|2, Sebastiano Lorusso2, Damiano Currado1|2, Letizia Pia Di Corcia1, Ludovica Lamberti1, Annalisa Marino2, Antonio Orlando1, Maria Quadrini1, Marta Vadacca2, Marta Vomero1, Luca Navarini1|2, Roberto Giacomelli1|2 | 1Rheumatology and Clinical Immunology, Department of Medicine, University of Rome Campus Biomedico, School of Medicine Rome, Italy; 2Clinical and Research Section of Rheumatology and Clinical Immunology Fondazione Policlinico Campus Biomedico Rome, Italy
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PO:25:083 | Overlap between Sjögren’s syndrome and lichen sclerosus: beyond coincidence? Emanuele Giovanni Grilli1, Ludovica Manisera1, Ilenia Fischetti1, Linda Mastromanno1, Martina Villa1, Angelica Gattamelata1, Fabrizio Conti1, Roberta Priori1|2, Serena Colafrancesco3|4 | 1Dipartimento di Medicina e Chirurgia, Università Milano-Bicocca; 2U.O. Reumatologia, IRCCS Fondazione San Gerardo dei Tintori, Monza; 3U.O. Pneumologia, IRCCS Fondazione San Gerardo dei Tintori, Monza; 4Rheumatology and Clinical Immunology, Istituto di Ricovero e Cura a Carattere Scientifico, IRCCS Humanitas Research Hosp, Rozzano, Milano, Italy
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PO:14:200 | Placental markers of angiogenesis in pregnant women with antiphospholipid syndrome: predictive role of SFLT-1, PLGF, and uterine artery doppler in preeclampsia Maria Bernadette Cilona1, Valentina Canti1, Martina Beschi2, Federica Pasi3, Serena Girardelli3, Mirko Pozzoni3, Maria Teresa Castiglioni3, Paolo Cavoretto3, Patrizia Rovere-Querini1|2 | 1Unit of Internal Medicine and Division of Immunology, Transplantation and Infectious diseases, IRCCS San Raffaele Hospital Milan, Italy; 2Vita-Salute San Raffaele University Milan, Italy; 3Department of Obstetrics and Gynecology, IRCCS San Raffaele Scientific Institute Milan, Italy
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PO:20:002 | Respiratory function tests predict bone mineral density in autoimmune rheumatic disease patients Andrea Zoli1, Panagiotis Garantziotis2, Sebastian Böltz2, Janina Auth2, Sara Bayat2, Jule Taubmann2, Anna-Maria Liphardt2, Maria Antonietta D'Agostino1, Christina Bergmann2, Georg Schett2. | 1Division of Rheumatology, Fondazione Policlinico Universitario A. Gemelli, IRCCS, Università Cattolica del Sacro Cuore, Roma, Italy; 2Department of Medicine 3, Rheumatology and Immunology, Friedrich Alexander Universität FAU, Erlangen, Germany.
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CO:05:4 | Natural language processing reveals demographic features, comorbidities, and clinical domains to predict treatment longevity of b/tsDMARDs in psoriatic arthritis Antonio Tonutti1|2, Pierandrea Morandini3, Cosimo Faeti3, Nicoletta Luciano1|2, Saverio D'Amico3, Victor Savevski3, Carlo Selmi1|2 | 1Department of Biomedical Sciences, Humanitas University Pieve Emanuele, Milan, Italy; 2Rheumatology and Clinical Immunology, IRCCS Humanitas Research Hospital Rozzano, Milan, Italy; 3Artificial Intelligence Unit, IRCCS Humanitas Research Hospital Rozzano, Milan, Italy
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PO:36:252 | Long-Term Outcomes of Patients with Takayasu Arteritis in the Era of Biological Agents: a Multicenter International Study Alessandro Tomelleri1, Durga Prasanna Misra2, Fatma Alibaz-Oner3, Chiara Marvisi4, Chiara Calabrese1, Upendra Rathore2, Aysegul Avcu3, Adele Del Giudice4, Elisabetta Olivi4, Caterina Ricordi4, Corrado Campochiaro1, Elena Baldissera1, Marco Matucci-Cerinic1, Haner Direskeneli3, Carlo Salvarani4, Lorenzo Dagna1 | 1IRCCS Ospedale San Raffaele, Unità di Immunologia, Reumatologia, Allergologia e Malattie Rare Milano, Italy; 2Sanjay Gandhi Postgraduate Institute of Medical Sciences SGPGIMS, Clinical Immunology and Rheumatology Lucknow Country, India; 3Marmara University, School of Medicine, Department of Internal Medicine, Division of Rheumatology Istanbul, Turkey; 4Azienda USL-IRCCS di Reggio Emilia, Unità di Reumatologia Reggio Emilia, Italy
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PO:23:052 | Muscular and myocardial involvement in antisynthetase syndrome: a retrospective real-life study Giulia Buonsante1|2|3, Giacomo De Luca1|2|3, Veronica Batani1|2, Daniele Scaramuzzi1|2|3, Lorenzo Dagna1|2|3, Marco Matucci-Cerinic1|2|3, Corrado Campochiaro1|2|3. | 1Unit of Immunology, Rheumatology, Allergy and Rare Diseases UNIRAR, IRCCS San Raffaele Hospital, Milano, Italy; 2Inflammation, Fibrosis and aging Initiative INFLAGE, IRCCS San Raffaele Hospital, Milano, Italy; 3Vita-Salute San Raffaele University, Milan, Italy, Milano, Italy.
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PO:16:234 | Differential efficacy of induction treatments for lupus nephritis at onset and relapses: an observational study Giuseppe Alvise Ramirez1|2, Gabriele D Gallina1, Chiara Calabrese1|2, Serena Nannipieri1|2, Marta Calatroni3|4, Francesco Reggiani3|4, Giovanni Benanti1, Enrica Paola Bozzolo1, Raffaele Ceniccola2, Luca Moroni1|2, Marco Matucci-Cerinic1|2, Gabriella Moroni3|4, Lorenzo Dagna1|2 | 1IRCCS San Raffaele Hospital, Unit of Immunology, Rheumatology, Allergy and Rare Diseases Milan, Italy; 2Vita- Salute San Raffaele University Milan, Italy; 3IRCCS Humanitas Research Hospital, Nephrology and Dialysis Division Rozzano, Milan, Italy; 4Humanitas University, Department of Biomedical Sciences Rozzano, Milan, Italy
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CO:07:4 | Clinical and psychosocial domains in fibromyalgia: a multidimensional questionnaire approach for personalized management. Results from an Italian monocentric study Eleonora Pedretti1, Francesca Regola1, Giulia Fontana1|2, Giulia Voltarel1|2, Michela Riolfo1|2, Anna Scalvini1, Ilaria Cavazzana1|2, Franco Franceschini1|2, Roberto Gorla1. | 1Rheumatology and Clinical Immunology Unit - ERN ReCONNET, ASST Spedali Civili of Brescia; 2Department of Clinical and Experimental Sciences, University of Brescia, Italy
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PO:24:063 | Interstitial lung disease in idiopathic inflammatory myopathy patients: efficacy and safety of nintedanib Giulia Buonsante1|2|3, Giacomo De Luca1|2|3, Veronica Batani1|2, Lorenzo Dagna1|2|3, Marco Matucci-Cerinic1|2|3, Corrado Campochiaro1|2|3 | 1Unit of Immunology, Rheumatology, Allergy and Rare Diseases UNIRAR, IRCCS San Raffaele Hospital Milano, Italy; 2Inflammation, Fibrosis and aging Initiative INFLAGE, IRCCS San Raffaele Hospital Milano, Italy; 3Vita-Salute San Raffaele University, Milano, Italy
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PO:33:191 | Evaluation of the living with pulmonary fibrosis questionnaire in patients with systemic sclerosis associated interstitial lung disease: monocentric results Claudia Barison1, Elda Piovani1, Eleonora Pedretti1, Eleonora Pazzi1, Liala Moschetti1, Ilaria Cavazzana1, Franco Franceschini1, Maria Grazia Lazzaroni1, Paolo Airò1. | 1Rheumatology and Clinical Immunology, Scleroderma Unit, ASST Spedali Civili of Brescia, University of Brescia, Brescia, Italy.
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PO:14:205 | Primary antiphospholipid antibody syndrome: association between new classification criteria manifestations and a higher-risk disease phenotype Sara Ferrigno1, Vittorio Forte2, Marco Panetta1, Sergio Lisena1, Giorgia Ranucci2, Luigi De Marco1, Elisabetta Greco1, Alberto Bergamini1, Maria Sole Chimenti1, Paola Conigliaro1. | 1Rheumatology, allergology and clinical immunology, Department of Systems Medicine, University of Rome Tor Vergata, Rome, Italy; 2Hematology, Department of Biomedicine and Prevention, University of Rome Tor Vergata, Rome, Italy.
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PO:07:108 | Achievement of Treatment Targets and Maintenance of Response with Upadacitinib in Patients with Moderate-to-Severe Rheumatoid Arthritis in a Real-world Setting: Final 2-year Outcomes from the UPHOLD Study Enrico Marchetta1, Andrew Östör2|8, Eugen Feist3, Prodromos Sidiropoulos4, Jérôme Avouac5, Martin Rebella6|7, Rajaie Namas9, Erin Mcdearmon Blondell10, Ivan Lagunes10, Tianming Gao10, Tim Shaw10, Suzan Attar11 | 1AbbVie Srl Roma, Italy; 2Monash University and Emeritus Research, Melbourne, Victoria, Melbourne, Australia; 3Helios Department of Rheumatology and Clinical Immunology, Vogelsang-Gommern, Vogelsang Gommern, Germany; 4Faculty of Medicine, University of Crete, Heraklion, Heraklion, Greece; 5Service de Rhumatologie, Hôpital Cochin, AP HP Centre Université Paris Cité, Parigi, France; 6Departamento de Medicina, Facultad de Medicina, Universidad de la República, Montevideo, Montevideo, Uruguay; 7Unidad de Enfermedades Autoinmunes Sistémicas, MUCAM, Montevideo, Montevideo, Uruguay; 8Australian National University, Camberra, Australia; 9Medical Subspecialties Institute, Division of Rheumatology, Cleveland Clinic Abu Dhabi, United Arab Emirates; 10AbbVie Inc., North Chicago, Illinois, United States of America Chicago, USA; 11King Abdulaziz University, Jeddah, Saudi Arabia
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PO:01:007 | Modulation of cellular senescence in psoriatic arthritis: exploring the potential impact of b/tsDMARDs treatment on telomere length, mtDNA copy number, and oxidative damage Eneida Cela1, Giada De Benedittis2, Arianna D'Antonio1, Andrea Latini3, Chiara Morgante2, Cinzia Cicacci3, Paola Conigliaro1, Mauro Fatica1, Giulia Mori1, Giuseppe Novelli2, Paola Borgiani2, Maria Sole Chimenti1. | 1Rheumatology, Allergology and Clinical Immunology, Department of System Medicine, University of Rome Tor Vergata, Rome, Italy; 2Department of Biomedicine and Prevention, Section of Genetics, University of Rome Tor Vergata, Rome, Italy; 3UniCamillus Saint Camillus International University of Health Sciences, Rome, Italy.
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PO:26:088 | Rheumatologic immune-related adverse events from immune checkpoint inhibitors: a monocentric retrospective study Giulio Fraticelli1|2, Nicola Farina1|2, Alessandro Tomelleri1|2, Marco Matucci Cerinic1|2, Corrado Campochiaro1|2, Lorenzo Dagna1|2. | 1Unit of Immunology, Rheumatology, Allergy and Rare Diseases UNIRAR, IRCCS San Raffaele Hospital, Milano, Italy; 2Inflammation, Fibrosis and Ageing Initiative INFLAGE, IRCCS San Raffaele Hospital, Milano, Italy.
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PO:16:227 | Anifrolumab for Systemic Lupus Erythematosus: Preliminary Safety and Efficacy Findings from the Italian Experience Paola Bizioli1|2, Chiara Orlandi1|2, Claudia Barison1|2, Cesare Tomasi3, Alessia Caproli1, Silvia Piantoni1|2, Simona Signorini4, Emirena Garrafa4, Cecilia Nalli1, Micol Frassi1, Ilaria Cavazzana1|2, Micaela Fredi1|2, Franco Franceschini1|2 | 1Rheumatology and Clinical Immunology Unit - ERN ReCONNET, ASST Spedali Civili of Brescia, Italy; 2Department of Clinical and Experimental Sciences, University of Brescia, Italy; 3Department of Clinical and Experimental Sciences, University of Brescia, Italy; 4Laboratory of Clinical Chemistry, Department of Molecular and Translational Medicine, University of Brescia, Italy
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CO:07:5 | Enhanced fibroblast signatures in females with early rheumatoid arthritis highlights a potential basis for poorer treatment outcomes Benedetta Monosi1, James Perera2, Alessandra Nerviani2|3, Maria Sole Chimenti1, Felice Rivellese2|3, Costantino Pitzalis2|3|4. | 1Rheumatology, Allergology and Clinical Immunology, Department of Systems Medicine, University of Rome Tor Vergata, Rome, Italy; 2Centre for Experimental Medicine and Rheumatology, William Harvey Research Institute, Queen Mary University of London, London, UK; 3Barts Health NHS Trust and Barts Biomedical Research Centre, National Institute for Health and Care Research, London, UK; 4Department of Biomedical Sciences Humanitas University and IRCCS Humanitas Research Hospital, Milano, Italy
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PO:24:064 | IPF vs CTD-ILD: Survival and Lung Function from an Italian Real-World Cohort Marco Fornaro1, Donato Lacedonia2, Lorenzo Cavagna3, Paolo Airò4, Marco Sebastiani5, Gianluca Sambataro6, Fabio Cacciapaglia7, Angelica Napoletano1, Cosimo De Pace2, Pasquale Tondo2, Giulia Scioscia2, Eleonora Pedretti4, Maria Grazia Lazzaroni4, Carlo Vancheri8, Andreina Manfredi9, Lorenzo Binchessi3, Rocco Capece3, Michele De Ceglie10, Massimo Giotta11, Florenzo Iannone1 | 1Unit of Rheumatology, Department of Precision and Regenerative Medicine - Area Jonica DiMePRe-J, University of Bari, Bari, Italy; 2Department of Medical and Surgical Sciences, University of Foggia Foggia, Italy; 3Department of Internal Medicine and Therapeutics, University of Pavia, Division of Rheumatology, Fondazione IRCCS, Pavia, Italy; 4Rheumatology and Clinical Immunology Unit, Department of Clinical and Experimental Sciences, ASST Spedali Civili Brescia, Italy; 5Rheumatology Unit, AUSL Piacenza, Department of Medicine and Surgery, University of Parma, Parma, Italy; 6Department of Medicine and Surgery, University of Enna Kore, Enna, Italy; 7Rheumatology Service, F. Miulli Hospital and Department of Medicine and Surgery, LUM University, Casamassima, Italy; 8Department of Clinical and Experimental Medicine, Regional Referral Center for Rare Lung Diseases, Catania, Italy; 9Rheumatology Unit, IRCCS Santa Maria Nuova Reggio Emilia, University of Modena, Modena, Italy; 10DIM, Interdisciplinary Department of Medicine, Section of Diagnostic Imaging, University of Bari, Bari, Italy; 11Health Prevention Department, Local Health Authority of Brindisi, Brindisi, Italy
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PO:07:103 | Tocilizumab use in patients with rheumatoid arthritis and malignancy: a monocentric experience Vittorio Dibenedetto1|2|3, Nicola Farina1|2, Nicola Boffini1|2, Alessandro Tomelleri1|2, Adriana Cariddi1|2, Elena Baldissera1|2, Marco Matucci-Cerinic1|2|3, Lorenzo Dagna1|2|3. | 1Unit of Immunology, Rheumatology, Allergy and Rare Diseases, IRCCS San Raffaele Hospital, Milano, Italy; 2Inflammation, Fibrosis and Ageing Intitiative INFLAGE, IRCCS San Raffaele Hospital, Milano, Italy; 3Vita-Salute San Raffaele University, Milano, Italy.
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PO:14:199 | Preliminary data of a multicentric study on safety and efficacy of assisted reproductive techniques in pregnant women with systemic autoimmune diseases Valentina Canti1, Maria Bernadette Cilona1, Giuditta Gorgone1, Federica Pasi1, Antonia Calligaro2, Francesca Ruffilli3, Francesca Crisafulli6, Maria Tonello2, Eleonora Giacobbe4, Alba Chiara Pozzi6, Maria Chiara Gerardi4, Melissa Padovan3, Emanuele Bizzi5, Enrico Papaleo1, Beatrice Maranini3, Marcello Govoni3, Massimiliano Epis4, Angela Tincani6, Andrea Doria2, Patrizia Rovere Querini1 | 1IRCCS Ospedale San Raffaele and VitaSalute San Raffaele Milano, Italy; 2Rheumatology Unit, Departement of Medicine, University Hospital of Padua Padova, Italy; 3Rheumatology Unit, Azienda Ospedaliero Universitaria S. Anna Ferrara, Department of Medical Sciences, University of Fe Ferrara, Italy; 4ASST Grande Ospedale Metropolitano Niguarda Milano, Italy; 5Internal Medicine, Fatebenefratelli Hospital Milano, Italy; 6Rheumatology and Immunology Unit, ASST Spedali Civili Brescia e Università degli Studi di Brescia, Italy
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PO:15:218 | Evaluation of leukocyte expression of ecto-nucleotidase in patients with systemic lupus erythematosus Luca Rapino1, Simona Truglia1, Fulvia Ceccarelli1, Francesca Romana Spinelli1, Silvia Mancuso1, Giada La Spina1, Hector Rincon Arvalo2, Thomas Doerner2, Ana Luisa Stefanski2, Fabrizio Conti1. | 1La Sapienza Università di, Roma, - Dipartimento di Scienze Cliniche Internistiche Anestesiologiche e Cardiovascolare, Roma, Italy; 2Charité Universitätsmedizin - Department of Rheumatology and Clinical Immunology, Berlino, Germany.
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PO:37:259 | Is there a seasonal pattern in giant cell arteritis? Revisiting the evidence in a large monocentric cohort of 1203 patients Milena Bond1, Philipp Bosch2, Aaron Juche3, Hans Bastian3, Wolfgang Schmidt4. | 1Department of Rheumatology, Hospital of Bruneck ASAA-SABES, Teaching Hospital of the Paracelsius Medical University Brunico Italy; 2Department of Rheumatology and Immunology, Medical University of Graz, Graz, Austria; 3Medical Centre for Rheumatology Berlin-Buch, Immanuel Krankenhaus Berlin Berlin Germany; 4Waldfriede Hospital, Rheumatology, Berlin, Germany.
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PO:06:090 | Validation of 'Clinical Red Flags' for RA-ILD in an Italian cohort: the role fo Dyspnea, Cough and Crackles Eneida Cela1, Chiara Bonini1, Francesco Cavalli2, Alessandra Luciano3, Barbara Kroegler1, Josuel Ora2, Alberto Bergamini1, Marcello Chiocchi3, Paola Rogliani2, Paola Conigliaro1, Maria Sole Chimenti1 | 1Rheumatology, Allergology and Clinical Immunology, Department of System Medicine, University of Rome Tor Vergata, Rome, Italy; 2Division of Respiratory Medicine, University Hospital Policlinico Tor Vergata, Rome, Italy; 3Department of Diagnostic Imaging and Interventional Radiology, University of Rome, Tor Vergata, Rome, Italy
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PO:32:187 | AI-assisted reading outperforms visual scoring of pulmonary CT scans to predict interstitial lung disease progression in systemic sclerosis Francesca Motta1, Antonio Tonutti1, Federica Catapano2, Gianluca Sellaro2, Francesco Amati3, Anna Stainer3, Calogero Messana2, Stefano Erba1, Stefano Aliberti3, Marco Francone2, Carlo Selmi1, Maria De Santis1 | 1Humanitas University and IRCCS Humanitas Research Hospital, Department of Rheumatology and Clinical Immunology Rozzano, Milan, Italy; 2IRCCS Humanitas Research Hospital, Department of Radiology Rozzano, Milan, Italy; 3IRCCS Humanitas Research Hospital, Respiratory Unit Rozzano, Milan, Italy
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PO:16:232 | Belimumab step-down dose spacing in patients with systemic lupus erythematosus in persistent clinical remission: experience from a multicentric cohort Alice Bartoletti1, Laura Giudice1, Lorenza Maria Argolini1|2, Giuseppe Alvise Ramirez3, Luca Moroni3, Tommaso Schioppo4, Chiara Bellocchi5|6, Annalaura Fasiello6, Lorenzo Beretta6, Lorenzo Dagna3, Roberto Caporali1, Maria Gerosa1. | 1UO Clinica Reumatologica, ASST Gaetano Pini CTO, Milano, Italy; 2UOC Medicina fisica e riabilitazione specialistica, ASST Gaetano Pini CTO, Milano, Italy; 3Unit of Immunology, Rheumatology, Allergy and Rare Diseases, IRCCS San Raffaele Hospital, Vita-Salute San Raffa Milano Italy; 4Medicina Generale II, Servizio di Reumatologia, Ospedale San Paolo, ASST Santi Paolo Carlo, Milano, Italy; 5Department of Clinical Sciences and Community Health, University of Milan, Dipartimeto di Eccellenza 2023-2027, Milano, Italy; 6Referral Centre for Systemic Autoimmune DIseases, Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico, Milano, Italy
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PO:31:172 | Age and timing of onset of Raynaud's phenomenon and first non-Raynaud sign/symptom as prognostic factors in systemic sclerosis: a retrospective analysis from the systemic sclerosis progression investigation registry of the Italian Society for Rheumatology Silvia Peretti1, Cosimo Bruni2, Silvia Laura Bosello3, Fabio Cacciapaglia4-5, Corrado Campochiaro6-7, Veronica Codullo8, Lorenzo Dagna6-7, Rossella De Angelis9, Giacomo De Luca6-7, Dilia Giuggioli10, Serena Guiducci1, Florenzo Iannone4, Francesca Ingegnoli11, Valeria Riccieri12, Marco Matucci Cerinic6-7, Clodoveo Ferri10-13, Silvia Bellando Randone1. | 1Division of Rheumatology, Scleroderma Unit, Department of Experimental and Clinical Medicine, University of Florence, AO, Firenze, Italy; 2Division of Rheumatology, University Hospital Zurich, University of Zurich, Zurich, Switzerland; 3Rheumatology Division, Catholic University of the Sacred Heart, Fondazione Policlinico Universitario A. Gemelli- IRCCS, Roma, Italy; 4Rheumatology Unit, Department of Precision and Regenerative Medicine-Ionian Area, University of Bari Aldo Moro, Bari, Italy; 5Reumatology Service, Internal Medicine Unit F.Miulli General Hospital, Acquaviva delle Fonti -Department of Medicine a, Bari, Italy; 6Unit of Immunology, Rheumatology, Allergy and Rare Diseases UnIRAR, Inflammation, Fibrosis and Ageing initiative INFL, Milano, Italy; 7Vita-Salute San Raffaele University, Milano, Italy; 8Department of Internal Medicine and Therapeutics, Università di Pavia, Italy; Division of Rheumatology, Fondazione IRCCS, Pavia, Italy; 9Rheumatology Unit, Department of Clinical and Molecular Sciences, Polytechnic University of Marche, Ancona, Italy; 10Rheumatology Unit, School of Medicine, University of Modena and Reggio Emilia, Modena, Italy; 11Division of Clinical Rheumatology, ASST Pini, Dept. of Clinical Sciences and Community Health, Research Center for Adul, Milano, Italy; 12Department of Rheumatology, Sapienza University of Rome, Roma, Italy; 13Rheumatology Clinic Madonna dello Scoglio Crotonei, Crotone, Italy.
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PO:15:214 | Identification of SLE patients with high-levels Type 2 SLE through the polysymptomatic distress scale (PSD): correlations with other PROs and differences in clinical phenotypes in a multicentric cohort Micaela Fredi1|2, Giorgia Gozzoli1|2, Federica Bonaso1|2, Silvia Ebe Della Pina1|2, Claudia Barison1|2, Irene Lorenzini2, Anna Mattiuzzo2, Raffaele Pericotti2, Marcelo Neto3, Sofia Avedo4, Clàudia Oliveira4, Luis Sousa Ines3, Franco Franceschini1|2 | 1Rheumatology and Clinical Immunology, ASST Spedali Civili of Brescia, ERN-ReCONNET Center, Brescia, Italy; 2Department of Clinical and Experimental Sciences, University of Brescia, Brescia, Italy; 3Rheumatology Department, Centro Hospitalar Universitário de Coimbra - ULS Coimbra, Coimbra, Portugal; 4Rheumatology Department, ULS Aveiro, Aveiro, Portugal
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CO:06:1 | Predictors of damage accrual in a monocentric cohort of patients with Behçet’s syndrome (BS) evaluated with BS overall damage index in real-life clinical practice Giulia Voltarel1|2, Francesca Crisafulli1|2, Alba Chiara Pozzi1|2, Anita Melzani2, Micol Frassi1, Ilaria Cavazzana1|2, Franco Franceschini1|2, Paolo Airò1. | 1Rheumatology and Clinical Immunology Unit - ERN ReCONNET, ASST Spedali Civili of Brescia; 2Department of Clinical and Experimental Sciences, University of Brescia, Italy
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PO:31:168 | Risk factors for cancer in systemic sclerosis, impact on disease phenotype and prognosis, and proposal of machine learning-based personalized screening strategies: insights from an EUSTAR study Antonio Tonutti1|2, Francesca Motta1|2, Stefano Erba1|2, Britta Maurer3, Cristiana Sieiro Santos3, Duygu Temiz Karadag3, Elena Rezus3, Elisabetta Zanatta3, Fabiola Atzeni3, Francesco Benvenuti3, Gabor Kumanovics3, Gabriella Szucs3, Gianluca Moroncini3, Gonçalo Boleto3, Leila Caillault3, Lilian Maria Lopez Nunez3, Masataka Kuwana3, Massimiliano Limonta3, Maurizio Cutolo3, Oliver Distler3, Radim Bevcar3, Roberto Giacomelli3, Rossella De Angelis3, Serena Guiducci3, Stefano Stano3, Valeria Riccieri3, Yasser El Miedany3, Sophie Blaise3, Carlo Selmi1|2, Maria De Santis1|2 | 1Department of Biomedical Sciences, Humanitas University Pieve Emanuele, Milan, Italy; 2Rheumatology and Clinical Immunology, IRCCS Humanitas Research Hospital Rozzano, Milan, Italy; 3EUSTAR collaborators EUSTAR * OTHER
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PO:32:185 | Deep-learning analysis of high-resolution computed tomography images predicts progression and mortality in systemic sclerosis related interstitial lung disease Valentina Boni1, Rosa D'Abronzo2, Piergiacomo Cerasuolo1, Lucio Calandriello2, Giuseppe Cicchetti2, Gerlando Natalello1, Bruno Iovene5, Francesco Varone5, Giacomo Sgalla5, Luca Richeldi5, Anna Rita Larici2|4, Maria Antonietta D'Agostino1|3, Silvia Laura Bosello1|3, Enrico De Lorenzis1. | 1Division of Rheumatology and Clinical Immunology Catholic Univeristy of the Sacred Heart, Rome, Italy; 2Department of Diagnostic Imaging, Oncological Radiotherapy and Hematology, Diagnostic Imaging Area, Catholic University, Rome, Italy; 3Department of Geriatric and Orthopaedic Sciences, Catholic Univeristy of the Sacred Heart, Rome, Italy; 4Department of Radiological and Hematological Sciences, Section of Radiology, Catholic Univeristy of the Sacred Heart, Rome, Italy; 5Division of Pulmonary Medicine, Catholic University of the Sacred Heart, Roma, Italy.
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PO:12:187 | Maternal Hypertensive Disorders in Pregnant Women with Rheumatic Diseases and long-term Cardiovascular Outcomes: preliminary data of a single centre experience Margherita Rinaldi1, Paolo Semeraro1, Francesca Crisafulli1, Matteo Filippini2, Maria Grazia Lazzaroni1, Cecilia Nalli1, Liala Moschetti1, Marco Taglietti2, Chiara Loardi3, Rossana Orabona3, Francesca Ramazzotto3, Sonia Zatti3, Laura Andreoli1, Angela Tincani1, Micaela Fredi1, Ilaria Cavazzana1, Franco Franceschini1 | 1Department of Clinical and Experimental Sciences, University of Brescia, Italy; 2Rheumatology and Clinical Immunology, ASST Spedali Civili of Brescia, ERN-ReCONNET Center Brescia, Italy; 3Gynaecology and Obstetrics Unit ASST Spedali Civili di Brescia, Italy
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