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PO:21:028 | A difficult case of VEXAS syndrome: management of myelodysplastic syndrome associated with systemic inflammation and infectious complications Sandra Lombardi1, Monica Regis1, Stefano De Luca1, Monica Poiani2, Rossella Stella2, Elisa Lucchini2, Francesco Zaja2, Fabio Fiammengo1 | 1SC Medicina Interna, Azienda Sanitaria Universitaria Giuliano Isontina, Gorizia; 2SC Ematologia, Azienda Sanitaria Universitaria Giuliano Isontina, Trieste, Italy
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PO:31:163 | Safety and tolerability of home-based prostacyclin analogue therapy in vascular manifestations of the scleroderma spectrum: results of a monocentric study Alice Dionisi1, Lucrezia Verardi2, Annacarla Finucci2, Paola Volpe2, Anna Cinzia Raspa2, Paola Cipriani1, Raffaele Zicolella2 | 1Reumatologia,Dipartimento di Sscienze Cliniche Applicate e Biotecnologiche, Università degli Studi dell'Aquila; 2UOC Reumatologia, Ospedale Civile di Pescara, Italy
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PO:16:235 | Anifrolumab in systemic lupus erythematosus: real-life experience of a single-center cohort Filippo Vesentini1, Luca Iaccarino1, Federico Arru2, Greta Hulej1, Anna Giorgia Osele1, Noemi Merra1, Davide Ragno1, Andrea Doria1, Margherita Zen1 | 1UOC Reumatologia, Dipartimento di Medicina DIMED, Università degli Studi di Padova; 2UO Medicina, ASL 3 Nuoro, Italy
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PO:07:103 | Tocilizumab use in patients with rheumatoid arthritis and malignancy: a monocentric experience Vittorio Dibenedetto1|2|3, Nicola Farina1|2, Nicola Boffini1|2, Alessandro Tomelleri1|2, Adriana Cariddi1|2, Elena Baldissera1|2, Marco Matucci-Cerinic1|2|3, Lorenzo Dagna1|2|3. | 1Unit of Immunology, Rheumatology, Allergy and Rare Diseases, IRCCS San Raffaele Hospital, Milano, Italy; 2Inflammation, Fibrosis and Ageing Intitiative INFLAGE, IRCCS San Raffaele Hospital, Milano, Italy; 3Vita-Salute San Raffaele University, Milano, Italy.
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PO:14:202 | Use of anifrolumab in the treatment of the hematological manifestations of systemic lupus erythematosus: a single-centre case series Gaia Ferracane1|2, Jessika Dichiara1|2, Elena Manna1|2, Lorenzo Mattia Bianchessi1|2, Giovanni Zanframundo1|2, Serena Bugatti1|2, Veronica Codullo1|2, Lorenzo Cavagna1|2, Francesca Bottazzi1|2 | 1Department of Internal Medicine and Therapeutics, Università di Pavia; 2Division of Rheumatology, IRCCS Policlinico San Matteo, Pavia, Italy
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PO:20:006 | Efficacy of denosumab in glucocorticoid-induced osteoporosis patients with prior exposure to intravenous aminobisphosphonates Kiren Khalid1, Alessandro Giollo1, Mariangela Salvato1, Francesca Frizzera1, Lorenzo Di Luozzo1, Bernd Raffeiner2, Andrea Doria1 | 1Rheumatology Unit, Department of Medicine - DIMED, University of Padova, Padova, Italy; 2Department of Rheumatology, Bolzano Central Hospital, Bolzano, Italy
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PO:02:025 | Real-World Comparative Effectiveness of Upadacitinib in Psoriatic Arthritis: Evaluation of Switching to Upadacitinib Versus Tumor Necrosis Factor Inhibitors or Interleukin-17 Inhibitors After First-Line Tumor Necrosis Factor Inhibitors Valentina Carlini1, Philip Mease2, William Tillett3, Xiaolan Ye4, Christopher Saffore4, Molly Edwards5, Isabel Truman5, Sophie Barlow5, Jayne Stigler4, Bhumik Parikh4, Daniel Aletaha6 | 1Abbvie srl Roma, Italy; 2University of Washington School of Medicine Seattle, United States Minor Outlying Islands; 3Department of Rheumatology, Royal National Hospital for Rheumatic Diseases Bath, United Kingdom; 4Abbvie Inc. North Chicago, United States Minor Outlying Islands; 5Adelphi Real World Bollington, United Kingdom; 6Division of Rheumatology, Department of Medicine, Medical University of Vienna, Vienna, Austria
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PO:06:079 | Weighing the burden: how body mass index shapes clinical outcomes in rheumatoid arthritis. Insights from a large Italian cohort Marco Capodiferro1, Marco Fornaro1, Gian Luca Erre2, Matteo Piga3, Elena Bartoloni Bocci4, Andreina Manfredi5, Ennio Giulio Favalli6, Maria Sole Chimenti7, Serena Guiducci8, Eleonora Celletti9, Addolorata Corrado10, Alessandro Giollo11, Simone Parisi12, Ivan Giovannini13, Elisa Gremese14, Garifallia Sakellariou15, Ombretta Viapiana16, Fabiola Atzeni17, Francesca Romana Spinelli18, Fabio Cacciapaglia1|19. | 1Rheumatology Unit, Department of Precision and Regenerative Medicine and Ionian Area DiMePRe-J University of Bari, Bari, Italy; 2Dipartimento di Scienze Mediche, Chirurgiche e Sperimentali, Università degli Studi di Sassari, Sassari, Italy; 3Rheumatology Unit, AOU Cagliari, Department of Medical Sciences and Public Health, University of Cagliari, Cagliari, Italy; 4Rheumatology Unit, Department of Medicine and Surgery, University of Perugia, Perugia, Italy; 5Rheumatology Unit, Azienda Ospedaliera Universitaria Policlinico of Modena, Modena, Italy; 6Dpt of Rheumatology, G. Pini Institute, Milano, Italy; 7Rheumatology, Allergology and Clinical Immunology, Department of Systems Medicine, University of Rome Tor Vergata, Rome, Italy; 8Department of Experimental and Clinical Medicine, Division of Rheumatology, University of Florence, Firenze, Italy; 9Rheumatology Unit, SS Annunziata Hospital, Chieti, Italy; 10Rheumatology Unit, Department of Medical and Surgical Sciences, University of Foggia, Foggia, Italy; 11Rheumatology Unit, Department of Medicine, University of Padova Hospital Trust, Padova, Italy; 12Rheumatology Department, A.O.U. Città della Salute e della Scienza, Torino, Italy; 13Rheumatology Department, Santa Maria della Misericordia Hospital, Udine, Italy; 14Rheumatology and Clinical Immunology, IRCCS Humanitas Research Hospital, Rozzano (MI), Italy; 15Department of Internal Medicine and Therapeutics, University of Pavia, Istituti Clinici Scientifici Maugeri, Pavia, Italy; 16Rheumatology Unit, Department of Medicine, University and Azienda Ospedaliera Universitaria Integrata of Verona, Verona, Italy; 17Rheumatology Unit, Department of Experimental and Internal Medicine, University of Messina, Messina, Italy; 18Reumatology Unit, Department of Internal, Anesthesiological, and Cardiovascular Clinical Sciences, Sapienza University, Roma, Italy; 19Miulli General Hospital Acquaviva - Department of Medicine and Surgery, LUM F. De Gennaro University, Casamassima (BA), Acquaviva delle Fonti (BA), Italy.
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PO:16:233 | Efficacy of voclosporin on nephritis in patients with variable gain of function of TLR7 affected by lupus: clinical case Veronica Spedicato1, Laura Coladonato1, Marco Fornaro1, Marlea Lavista1, Daniele Sabella1, Marco Capodiferro1, Maria Morrone1, Crescenzio Scioscia1, Giuseppe Lopalco1, Florenzo Iannone1 | 1Unit of Rheumathology, Department of Precision and Regenerative Medicina, Area JonicaJ, University of Bari, Italy
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PO:19:286 | Genetic testing reveals an unexpected case of mevalonate kinase deficiency in a 37-year-old patient with AA renal amyloidosis and good response to colchicine Francesca Crisafulli1, Paolo Airò2, Federica Mescia3, Gianmarco Lugli3, Gianfranco Savoldi4, Claudia Izzi3|5, Federico Alberici3, Marco Cattalini6, Franco Franceschini1, Micol Frassi2. | 1Rheumatology and Clinical Immunology Unit, ASST Spedali Civili and University of Brescia, Brescia, Italy; 2Rheumatology and Clinical Immunology Unit, ASST Spedali Civili of Brescia, Brescia, Italy; 3U.O Nefrologia, ASST Spedali Civili di Brescia e Università degli Studi di Brescia, Brescia, Italy; 4Medical genetics Laboratory, Laboratory Department ASST Spedali Civili di Brescia, Brescia, Italy; 5Struttura Complessa di Genetica Clinica, ASST Spedali Civili di Brescia, Brescia, Italy; 6Pediatrics Clinic, University of Brescia and ASST Spedali Civili of Brescia, Brescia, Italy.
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CO:09:6 | Risk of disease flare during pregnancy and postpartum in inflammatory arthritis: association with therapy discontinuation in the prospective P-RHEUM.it study Dina Zucchi1, Chiara Tani1, Francesca Crisafulli2, Alessia Gatti2, Maria Gerosa3, Cecilia Chighizola3, Melissa Padovan4, Salvatore D'Angelo5, Florenzo Iannone6, Maria Sole Chimenti7, Claudia Lomater8, Francesca Serale9, Veronique Ramoni10, Oscar Epis11, Bernd Raffeiner12, Ariela Hoxha13, Andrea Doria14, Leonardo Santo15, Valentina Canti16, Francesca Bellisai17, Giovanna Cuomo18, on behalf of the P-Rheumit Investigators19, Greta Carrara20, Cristina Di Nicola20, Davide Rozza20, Carlo Alberto Scirè20, Maria Chiara Gerardi11, Angela Tincani2, Laura Andreoli2, Marta Mosca1. | 1Rheumatology Unit, University of Pisa and Azienda Ospedaliero Universitaria Pisana; 2Rheumatology and Clinical Immunology Unit, ASST Spedali Civili, Brescia; 3Clinical Rheumatology Division, ASST Gaetano Pini-CTO and University of Milano; 4Rheumatology Unit, Azienda Ospedaliero-Universitaria S. Anna and University of Ferrara; 5Rheumatology Department of Lucania - San Carlo Hospital, Potenza; 6Rheumatology Unit, DiMePRE-J, University of Bari; 7Department of Systems Medicine, Rheumatology, Allergology and Clinical Immunology, University of Rome-Tor Vergata, Roma; 8Torino Academic Rheumatology Center, A.O. Mauriziano di Torino, University of Torino; 9Rheumatology Unit, ASL CN1 Cuneo; 10Internal Medicine Department, ASST Lodi - Ospedale Maggiore di Lodi; 11Division of Rheumatology, Multispecialist Medical Department, Grande Ospedale Metropolitano Niguarda, Milano; 12Department of Rheumatology, Central Hospital of Bolzano SABES-ASDAA, Bolzano; 13General Medicine and Thrombosis and Hemorrhagic Unit, Department of Medicine, University of Padova; 14Rheumatology Unit, Department of Medicine, University of Padova; 15Rheumatology Unit, Mons. Dimiccoli Hospital, Barletta; 16Division of Immunology, Transplantation and Infectious Diseases, IRCCS Ospedale San Raffaele, Milano; 17Rheumatology Unit, Department of Medicine, Surgery and Neurosciences, University of Siena; 18Precision Medicine Department, University of Campania L. Vanvitelli, Napoli; 19The Italian Society for Rheumatology; 20Epidemiology Research Unit of the Italian Society for Rheumatology, Milano, Italy
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PO:16:234 | Differential efficacy of induction treatments for lupus nephritis at onset and relapses: an observational study Giuseppe Alvise Ramirez1|2, Gabriele D Gallina1, Chiara Calabrese1|2, Serena Nannipieri1|2, Marta Calatroni3|4, Francesco Reggiani3|4, Giovanni Benanti1, Enrica Paola Bozzolo1, Raffaele Ceniccola2, Luca Moroni1|2, Marco Matucci-Cerinic1|2, Gabriella Moroni3|4, Lorenzo Dagna1|2 | 1IRCCS San Raffaele Hospital, Unit of Immunology, Rheumatology, Allergy and Rare Diseases Milan, Italy; 2Vita- Salute San Raffaele University Milan, Italy; 3IRCCS Humanitas Research Hospital, Nephrology and Dialysis Division Rozzano, Milan, Italy; 4Humanitas University, Department of Biomedical Sciences Rozzano, Milan, Italy
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PO:37:270 | Efficacy of iloprost as a therapy for skin ulcers in cryofibrinogenemia and cryoglobulinemia: a complex case in a fragile patient Luca Keller Sarmiento1, Amelia Spinella2, Marco De Pinto2, Giorgia Roveta1, Dilia Giuggioli1|2. | 1Università degli Studi di Modena e Reggio Emilia, Modena, Italy; 2Unità di Reumatologia del Policlinico di Modena, Modena, Italy.
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PO:25:079 | Anifrolumab in refractory dermatomyositis: a case report Chiara Calabrese1, Corrado Campochiaro1|2, Giacomo De Luca 1|2, Veronica Batani1, Marco Matucci-Cerinic1|2, Lorenzo Dagna 1|2 | 1Dipartimento di Reumatologia e Scienze Mediche, ASST Centro Specialistico Ortopedico Traumatologico Gaetano Pini-CTO Milano; 2Università degli Studi di Milano, Dipartimento di Fisiopatologia Medico-Chirurgica e Trapianti, Milano, Italy
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PO:36:246 | Early real-world outcomes with benralizumab in eosinophilic granulomatosis with polyangiitis: a monocentric retrospective Richard Borrelli1, Stefania Nicola1, Federica Corradi1, Iuliana Badiu1, Marzia Boem1, Valentina Marmora1, Simone Negrini1, Luisa Brussino1. | 1SCDU Immunologia e Allergologia, AO Mauriziano, Dipartimento di Scienze Mediche, Università degli Studi di Torino, Torino, Italy.
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PO:30:157 | Radiographic assessment of measurable osteoarticular damage in juvenile idiopathic arthritis (JIA) patients transitioning to adult care Serena Pastore4, Marta Klanmjsceck3, Andrea Guiotto1, Laura De Nardi5|6, Alessia Pin4, Lorenzo Cereser1|2, Andrea Taddio3|4, Luisa Occhipinti1, Luca Quartuccio1|2, Alberto Tommasini3|4, Alen Zabotti2 | 1Università degli Studi di Udine Udine, Italy; 2Ospedale Santa Maria della Misericordia Udine, Italy; 3Università degli Studi di Trieste Trieste, Italy; 4IRCCS Materno Infantile Burlo Garofolo Trieste, Italy; 5Università Tor Vergata Roma, Italy; 6Ospedale Pediatrico Bambino Gesù Roma, Italy
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PO:15:209 | Attainment of remission or lupus low disease activity state in single center Lupus Clinic Paola Tedoldi1|2, Silvia Ebe Lucia Della Pina1|2, Claudia Barison1|2, Chiara Orlandi1|2, Cecilia Nalli1, Micaela Fredi2, Ilaria Cavazzana1|2, Franco Franceschini1|2 | 1Rheumatology and Clinical Immunology Unit- ERN ReCONNET, ASST Spedali Civili of Brescia Brescia, Italy; 2Department of Clinical and Experimental Sciences, University of Brescia Brescia, Italy
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PO:14:204 | Risk stratification in systemic lupus erythematosus patients: improving the performances of a prediction model Lucia Lanzo1, Silvia Laura Bosello1, Livia Lilli2, Laura Antenucci2, Carlotta Masciocchi2, Marco Gorini3, Gabriella Castellino3, Luca Petricca1, Maria Rita Gigante1, Vivianaantonella Pacucci1, Pier Giacomo Cerasuolo1, Silvia Piunno1, Francesco Cristiano1, Cesare Gavotti1, Pier Luigi Rizzuti1, Rebecca Ventura1, Jacopo Lenkowicz2, Alfredo Cesario2, Stefano Patarnello2, Maria Antonietta D'Agostino1. | 1UOC di Reumatologia e Immunologia clinica - Fondazione Policlinico Universitario A. Gemelli IRCSS, UCSC, Roma, Italy; 2Fondazione Policlinico Universitario Agostino Gemelli IRCSS, Roma, Italy; 3AstraZeneca MIND, Milano, Italy.
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PO:35:234 | Sustained Vasculitis Quiescence and CS Reduction with Mepolizumab 100 mg Francesca Mascia1, Angelo Fassio2, Marco Zurlo1, Davide Chesini3, Francesco Pollastri2, Giovanni Adami2, Davide Gatti4, Maurizio Rossini4, Matteo Maule5, Gianentrico Senna1, Marco Caminati1 | 1University of Verona - Allergology and Clinical Immunology Verona, Italy; 2Policlinico G. B. Rossi - Rheumatology Verona, Italy; 3University of Verona - Faculty of Medicine and Surgery Verona, Italy; 4University of Verona - Rheumatology Verona, Italy; 5Policlinico G. B. Rossi - Allergology and Clinical Immunology Verona, Italy
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PO:35:228 | Polymyalgia rheumatica and giant cell arteritis induced by immune checkpoint inhibitors for cancer treatment: a systematic review and meta-analysis highlighting differences from the idiopathic forms Elvis Hysa1, Andrea Casabella2, Emanuele Gotelli1, Rosanna Campitiello1, Carlo Genova3, Enrica Teresa Tanda4, Carmen Pizzorni1, Alberto Sulli1, Vanessa Smith5, Marco Amedeo Cimmino6, Sabrina Paolino1, Maurizio Cutolo1. | 1Laboratory of Experimental Rheumatology and Academic Division of Clinical Rheumatology, Department of Internal Medicine, Genova, Italy; 2IRCCS Ospedale Policlinico San Martino, Genova, Italy; 3Academic Oncology Unit; IRCCS Ospedale Policlinico San Martino, Genova, Italy; 4UOC Medical Oncology Clinic 2, Department of Internal Medicine, University of Genova, Genova, Italy; 5Department of Internal Medicine, Ghent University, Department of Rheumatology, Ghent University Hospital, Ghent, Belgium; 6Rheumatology Outpatient Clinic, Villa Ravenna Chiavari Italy.
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PO:12:177 | Systemic inflammation and QTc interval prolongation in new-onset polymyalgia rheumatica: the effect of corticosteroid therapy Anna Colangelo1, Riccardo Accioli2, Viola Salvini2, Francesco Tromby1, Giulia Cruciani1, Martina Nicchi1, Biancamaria Pianese1, Francesca Lalli1, Anna Cantore2, Caterina Antonini1, Decoroso Verrengia2, Andrea Castellucci1, Giacomo Cafaro1, Carlo Perricone1, Roberto Gerli1, Pietro Enea Lazzerini2, Elena Bartoloni1 | 1SC Reumatologia. Università di Perugia, Italy; 2Dipartimento di Scienze Mediche, Università di Siena, Italy
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PO:20:002 | Respiratory function tests predict bone mineral density in autoimmune rheumatic disease patients Andrea Zoli1, Panagiotis Garantziotis2, Sebastian Böltz2, Janina Auth2, Sara Bayat2, Jule Taubmann2, Anna-Maria Liphardt2, Maria Antonietta D'Agostino1, Christina Bergmann2, Georg Schett2. | 1Division of Rheumatology, Fondazione Policlinico Universitario A. Gemelli, IRCCS, Università Cattolica del Sacro Cuore, Roma, Italy; 2Department of Medicine 3, Rheumatology and Immunology, Friedrich Alexander Universität FAU, Erlangen, Germany.
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CO:10:2 | Common variable immunodeficiency patients complicated by autoimmune and inflammatory rheumatic manifestations reveal high frequency of genetic variants potentially linked to inborn errors of immunity Paolo Semeraro1, Micol Frassi1, Silvia Clara Giliani2, Franco Franceschini1, Paolo Airò1. | 1Rheumatology and Clinical Immunology Unit, ERN ReCONNET, ASST Spedali Civili of Brescia and University of Brescia; 2Medical Genetic Laboratory, ASST Spedali Civili of Brescia and University of Brescia, Italy
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CO:06:2 | Deep immunophenotyping in patients with juvenile localized scleroderma reveals two distinct immunological endophenotypes Emiliano Marasco1, Angela Aquilani1, Rebecca Nicolai1, Ivan Caiello1, Fabrizio De Benedetti1. | 1Unità di Reumatologia, Ospdeale Pediatrico Bambino Gesù, Roma, Italy
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PO:25:082 | Progressive interstitial lung disease secondary to Sjögren's disease in a patient with inclusion body myositis complicated by dysphagia: a multidisciplinary approach and therapeutic challenges Emanule Cocchiara1, Francesco Falco1, Lucia Spaggiari3, Francesca Cozzini1|2, Lucia Dardani1, Gianluigi Bajocchi1, Andreina Manfredi1|2, Carlo Salvarani1|2 | 1Dipartimento di Medicina, Clinica Reumatologica, Udine; 2Università degli studi di Modena e Reggio Emilia, Modena; 3AUSL area NORD, Guastalla-Montecchio, Italy
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