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PO:32:185 | Deep-learning analysis of high-resolution computed tomography images predicts progression and mortality in systemic sclerosis related interstitial lung disease Valentina Boni1, Rosa D'Abronzo2, Piergiacomo Cerasuolo1, Lucio Calandriello2, Giuseppe Cicchetti2, Gerlando Natalello1, Bruno Iovene5, Francesco Varone5, Giacomo Sgalla5, Luca Richeldi5, Anna Rita Larici2|4, Maria Antonietta D'Agostino1|3, Silvia Laura Bosello1|3, Enrico De Lorenzis1. | 1Division of Rheumatology and Clinical Immunology Catholic Univeristy of the Sacred Heart, Rome, Italy; 2Department of Diagnostic Imaging, Oncological Radiotherapy and Hematology, Diagnostic Imaging Area, Catholic University, Rome, Italy; 3Department of Geriatric and Orthopaedic Sciences, Catholic Univeristy of the Sacred Heart, Rome, Italy; 4Department of Radiological and Hematological Sciences, Section of Radiology, Catholic Univeristy of the Sacred Heart, Rome, Italy; 5Division of Pulmonary Medicine, Catholic University of the Sacred Heart, Roma, Italy.
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PO:06:086 | Updated Systematic Literature Review and meta-analysis to Inform the Italian Society of Rheumatology Recommendations on the Treatment of Rheumatoid Arthritis-Associated Interstitial Lung Disease Angelo Fassio1, Marco Sebastiani9|10, Francesco Pollastri1, Chiara Crotti4, Nicola Ughi5, Enrico De Lorenzis6, Silvia Mancuso7, Massimo Radin8, Francesca Cozzini9, Greta Carrara11, Gianpiero Landolfi11, Roberto Rozza11, Andreina Manfredi2|3 | 1Rheumatology Unit, University of Verona, Verona, Italy; 2University of Modena and Reggio Emilia, Reggio Emilia, Italy; 3Rheumatology Unit, AUSL-IRCCS, Reggio Emilia, Italy; 4Bone Disease Unit, Department of Rheumatology and Medical Science, ASST-G.Pini-CTO, Milan, Italy; 5Division of Rheumatology, Multispecialist Medical Department, ASST Grande Ospedale Metropolitano Niguarda, Milano, Italy; 6Department of Aging Diseases, Orthopedic and Rheumatology, Rheumatology Division, P. Gemelli, Roma, Italy; 7Rheumatology Unit, Department of Clinical, Internal, Anaesthesiologic and Cardiovascular, Sciences, Sapienza, Roma, Italy; 8CMID, San Giovanni Bosco Hub Hospital ASL Città di Torino and Department of Clinical and Biological Sciences, Turin, Italy; 9Department of Medicine and Surgery, University of Parma, Parma, Italy; 10Rheumatology Unit, AUSL Piacenza, Piacenza, Italy; 11Unità Epidemiologica, SIR, Società Italiana di Reumatologia, Milano, Italy
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PO:27:112 | The impact of rurality in chronic inflammatory rheumatic diseases in the province of Udine (2014-2023): analysis of clinical outcomes and potential complications Simone Longhino1, Luigi Castrista2, Yvonne Beorchia2, Marco Driutti2, Elena Treppo1, Silvio Brusaferro3, Luca Quartuccio1 | 1Clinica di Reumatologia, Dipartimento di Medicina Specialistica; 2Istituto di Igiene ed Epidemiologia Valutativa; 3Accreditamento, Gestione del Rischio Clinico e Valutazione delle Performance Sanitarie, ASUFC, Udine, Italy
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PO:32:178 | Effectiveness of oral anticoagulants in precapillary pulmonary hypertension associated with systemic sclerosis: a EUSTAR cohort study Nicola Farina1, Silvia Bellando-Randone1, Hilde Jenssen-Bjørkekjær2, David Launay3, Patricia Carreira4, Paolo Airò5, Serena Guiducci1, Dilia Giuggioli6, Gabriela Riemekasten7, Carmen-Pilar Simeón Aznar8, Christina Bergmann9, Elise Siegart10, Ivan Castellví11, Lesley Ann Saketkoo12, Jeska De Vries-Bouwstra13, Philipp Klemm14, Ulf Müller-Ladner14, Alexandra Balbir-Gurman15, Vanessa Smith16, Florenzo Iannone17, Luca Idolazzi18, Christopher Denton19, Edoardo Rosato20, Britta Maurer1, Yannick Allanore1, Yoshiya Tanaka1, Elisabetta Zanatta1, Oliver Distler1, Marco Matucci-Cerinic1, Cosimo Bruni1 | 1Department of Experimental and Clinical Medicine, Scleroderma Unit, Division of Rheumatology, University of Florence, Az Firenze, Italy; 2Department of Rheumatology, Hospital of Southern Norway Kristiansand, Norway; 3National Reference Center for Pulmonary Arterial Hypertension Pulmotension Lille, France; 4Hospital Universitario 12 de Octubre, Rheumatology Department Madrid Spain; 5ASST Spedali Civili of Brescia, University of Brescia, Rheumatology and Clinical Immunology Unit Brescia, Italy; 6Scleroderma Unit, Rheumatology Unit, University Hospital of Modena and Reggio Emilia Modena, Italy; 7Universitätsklinikum Schleswig-Holstein, Klinik für Rheumatologie und klinische Immunologie Lübeck Germany; 8Hospital Universitario Vall d'Hebron, Department of Internal Medicine, Systemic Autoimmune Diseases Unit Barcelona Spain; 9University Hospital Erlangen, Department Internal Medicine 3 Erlangen Germany; 10Charité University Hospital, Department of Rheumatology Berlin Germany; 11Hospital de la Santa Creu i Sant Pau Baercelona Spain; 12New Orleans Scleroderma and Sarcoidosis Patient Care and Research Center New Orleans, USA; 13Leiden University Medical Center, Department of Rheumatology Leiden, The Netherlands; 14JLU Giessen, Campus Kerckhoff, Department of Rheumatology and Clinical Immunology Center Bad Nauheim Germany; 15Rambam Health Care Campus, Rheumatology Institute Haifa, Israel; 16University of Ghent, Department of Rheumatology Ghent, Belgium; 17Rheumatology DiMePReJ, University of Bari, School of Medicine Bari, Italy; 18University of Verona, Section of Rheumatology, Department of Medicine Verona, Italy; 19Royal Free London and University College London Medical School, Centre for Rheumatology London, United Kingdom; 20Sapienza University of Rome, Department of Translational and Precision Medicine Azienda Ospedaliero-Universitaria Policl Roma, Italy
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PO:12:179 | Cardiovascular outcomes of treat-to-target urate-lowering therapy in gout: emulated target trials Edoardo Cipolletta1, Davide Rozza2, Abhishek Abhishek3 | 1Azienda Ospedaliero Universitaria delle Marche, Ancona, Italy; 2Società Italiana di Reumatologia, Milano, Italy; 3University of Nottingham Nottingham, United Kingdom
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PO:01:006 | Increased risk of cancer recurrence or mortality associated with DMARDs? Laura Scagnellato1, Giacomo Cozzi1, Mariagrazia Lorenzin1, Mariangela Salvato1, Alessandro Giollo1, Bernd Raffeiner1, Antonia Calligaro1, Teresa Del Ross1, Sara Bindoli1, Margherita Zen1, Paolo Sfriso1, Andrea Doria1, Roberta Ramonda1. | 1UOC Reumatologia, Dipartimento di Medicina dei Sistemi DIMED, Ospedale Università di Padova, Padova, Italy.
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CO:12:1 | Inside the Heterogeneity of Primary Central Nervous System Vasculitis: A single-centre 40-year experience Carlo Salvarani1, Gene G Hunder2, Caterina Giannini2, Teresa Jh Christianson2, Robert D Brown2 | 1Azienda USL-IRCCS di Reggio Emilia e UNIMORE Reggio Emilia, Italy; 2Mayo Clinic Rochester, USA
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PO:32:187 | AI-assisted reading outperforms visual scoring of pulmonary CT scans to predict interstitial lung disease progression in systemic sclerosis Francesca Motta1, Antonio Tonutti1, Federica Catapano2, Gianluca Sellaro2, Francesco Amati3, Anna Stainer3, Calogero Messana2, Stefano Erba1, Stefano Aliberti3, Marco Francone2, Carlo Selmi1, Maria De Santis1 | 1Humanitas University and IRCCS Humanitas Research Hospital, Department of Rheumatology and Clinical Immunology Rozzano, Milan, Italy; 2IRCCS Humanitas Research Hospital, Department of Radiology Rozzano, Milan, Italy; 3IRCCS Humanitas Research Hospital, Respiratory Unit Rozzano, Milan, Italy
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PO:16:236 | Achieving a low disease activity state with a corticosteroid dose of 5 mg or less: observational study with anifrolumab in patients with systemic lupus erythematosus in Italy Alessandra Bortoluzzi1, Fulvia Ceccarelli2, Fabio Leo3, Paola Roccatagliata3, Chiara Tani4, Margherita Zen5 | 1Azienda Ospedaliera Universitaria Sant' Anna di Cona, Università di Ferrara Italy; 2Unità di Reumatologia, Università Sapienza Roma Italy; 3AstraZeneca S.p.a. Milano Italy; 4Università di Pisa e Azienda Ospedaliero Universitaria Pisana, Pisa Italy; 5Dipartimento di Medicina DIMED , Divisione di Reumatologia, Università di Padova, Italy
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PO:31:166 | S'/PAPs ratio in systemic sclerosis: a promising non-invasive index for early detection and prognosis of pulmonary hypertension. A step toward more accurate screening? Marco De Pinto1, Amelia Spinella1, Pierluca Macripò2, Alessia Laneri1, Benedetta Bongiovanni1, Maria Grazia Malandra1, Martina Orlandi1-3, Gianluca Pagnoni2, Arianna Maini2, Rosario Rossi2-4, Clodoveo Ferri1, Francesca Coppi2-3, Dilia Giuggioli1-3. | 1Rheumatology Unit, Azienda Ospedaliero-Universitaria Policlinico di Modena, University of Modena and Reggio Emilia, Modena, Italy; 2Cardiology Division, Azienda Ospedaliero-Universitaria Policlinico di Modena, Modena, Italy; 3Department of Medical and Surgical Sciences for Children and Adults, University of Modena and Reggio Emilia, Modena, Italy; 4Department of Biomedical, Metabolic and Neural Sciences, University of Modena and Reggio Emilia, Modena, Italy.
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CO:01:2 | BAG3 in systemic sclerosis: possible therapeutic target and biomarker for pulmonary fibrosis Claudia Iannone1|2, Margot De Marco3, Antonina Minniti1, Paola Manzo3, Angela D'Ardia3, Antonia Falco3, Liberato Marzullo3, Angela Rosato3, Maria Caterina Turco3, Roberto Caporali1|2, Nicoletta Del Papa1|2. | 1ASST G. Pini-CTO. UOC Clinica Reumatologica, Milano; 2Department of Clinical Sciences and Community Health, University of Milano; 3Department of Medicine, Surgery and Dentistry Schola Medica Salernitana, Baronissi (SA), Italy
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PO:32:176 | Outcomes of upfront combination vs monotherapy with rituximab or mycophenolate mofetil for systemic sclerosis interstitial lung disease: results from a European Scleroderma Trials and Research cohort study Devis Benfaremo1, Corrado Campochiaro2, Gábor Kumánovics3, Christina Bergmann4, Elisabetta Zanatta5, David Launay6, Serena Guiducci7, Mickael Martin8, Carolina De Souza Müller9, Carlomaurizio Montecucco10, Luc Mouthon11, Gabriella Szucs12, Kastriot Kastrati13, Marie-Elise Truchetet14, Madelon Vonk15, Francesco Del Galdo16, Marco Matucci-Cerinic2, Gianluca Moroncini1, Yannick Allanore17. | 1Department of Clinical and Molecular Sciences, Marche Polytechnic University, Marche University Hospital, Ancona, Italy; 2Vita-Salute San Raffaele University, San Raffaele Hospital, Milano, Italy; 3University of Pécs, Department Of Rheumatology And Immunology, Pécs, Hungary; 4University Hospital Erlangen, Department Internal Medicine 3, Erlangen, Germany; 5Padova University Hospital, Rheumatology Unit, Padova, Italy; 6Univ. Lille, Inserm, CHU Lille, Department of Internal Medicine and Clinical Immunology, Lille, France; 7University of Florence, Azienda Ospedaliera Universitaria Careggi, Firenze, Italy; 8Poitiers University Hospital, Department of Internal Medicine Poitiers France; 9Hospital de Clinicas da Universidade Federal do Parana Curitiba Brazil; 10Università di Pavia e IRCCS Fondazione Policlinico S. Matteo, Pavia, Italy; 11Hôpital Cochin, Department of Internal Medicine, Paris, France; 12University of Debrecen, Faculty of Medicine, Department of Rheumatology, Debrecen, Hungary; 13Medical University of Vienna, Department of Medicine III, Division of Rheumatology, Vienna, Austria; 14CHU de Bordeaux, Rheumatology department, Bordeaux, France; 15Radboudumc, Department of Rheumatology Nijmegen The Netherlands; 16Leeds Raynauds and Scleroderma Program, NIHR Biomedical Research Centre, Leeds, United Kingdom; 17Université Paris Cité, Cochin Hospital, Rheumatology Department, Paris, France.
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PO:33:202 | Assessment of Retinal Arteriolar Wall-to-Lumen Ratio and Renal Resistive Index in patients with Systemic Sclerosis Eleonora Pazzi1|2, Elda Piovani1|2, Claudia Barison1|2, Liala Moschetti1|2, Eleonora Pedretti1|2, Mariagrazia Lazzaroni1|2, Carolina De Ciuceis3, Claudia Agabiti-Rosei3, Giacomo Buso3|4, Paolo Baggi3, Claudia Rossini3, Cristina Bevacqua3, Maria Lorenza Muiesan3, Ilaria Cavazzana1, Franco Franceschini1, Paolo Airò2 | 1Rheumatology and Clinical Immunology, ASST Spedali Civili of Brescia, University of Brescia, Brescia, Italy; 2Scleroderma Unit, ASST Spedali Civili of Brescia, Brescia, Italy; 3Department of Clinical and Experimental Sciences, Division of Internal Medicine, ASST Spedali Civili of Brescia, Univers Brescia, Italy; 4University of Lausanne, Lausanne Switzerland
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PO:34:212 | Orofacial manifestations in systemic sclerosis: preliminary observational study and update of a single-center experience Amelia Spinella1, Marco De Pinto1, Giacomo Setti2, Martina Orlandi1|3, Samuele Veronesi2, Federica Lumetti1, Alessia Laneri1, Luca Keller Sarmiento1, Giorgia Roveta1, Gilda Sandri1|3, Pierantonio Bellini2, Ugo Consolo2, Dilia Giuggioli1|3 | 1Università degli Studi di Milano, Dipartimento di Scienze Cliniche e di Comunità, Milano; 2ASST G. Pini-CTO, UOC di Clinica Reumatologica, Milano; 3UOC di Reumatologia Clinica Pediatrica, ASST Gaetano Pini-CTO, Milano, Italy
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PO:31:161 | First-line diagnostic tests to intercept primary heart involvement in systemic sclerosis: clinical associations from the SPRING-SIR registry Antonio Tonutti1|2, Francesca Motta1|2, Rossella De Angelis3, Valeria Riccieri4, Silvia Laura Bosello5, Fabio Cacciapaglia6, Veronica Codullo7, Giacomo De Luca8, Francesca Ingegnoli9, Dilia Giuggioli10, Clodoveo Ferri10, Marco Matucci-Cerinic8, Carlo Selmi1|2, Maria De Santis1|2 | 1Department of Biomedical Sciences, Humanitas University Pieve Emanuele, Milan, Italy; 2Rheumatology and Clinical Immunology, IRCCS Humanitas Research Hospital Rozzano, Milan, Italy; 3Università Politecnica delle Marche Ancona, Italy; 4Università degli Studi di Roma La Sapienza Roma, Italy; 5Università Cattolica del Sacro Cuore Roma, Italy; 6Università degli Studi di Bari Aldo Moro Bari, Italy; 7Reumatologia, Fondazione IRCCS Policlinico San Matteo Pavia, Italy; 8Università Vita-Salute San Raffaele Milano, Italy; 9Università degli Studi di Milano, Italy; 10Università degli Studi di Modena e Reggio Emilia, Italy
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CO:03:1 | Distinct breath metabolomic signature in systemic sclerosis patients with pulmonary arterial hypertension Martina Iacubino1, Lorenzo Rocco1, Marco Vicenzi2|3, Chiara Bellocchi2|4, Marta Mozzo4, Adriana Severino3, Monica Caronni3, Alessandro Santaniello3, Gaia Montanelli3, Barbara Vigone3, Liam Grimmett5, Matthew Kerr5, Lorenzo Beretta3. | 1Scuola di specializzazione in Allergologia e Immunologia clinica, Università degli Studi di Milano; 2Dipartimento di Scienze Cliniche e Salute di Comunità, Dipartimento di Eccellenza 2023-2027, Università degli Studi di Milano; 3Dipartimento di Malattie Cardio-Toraciche-Vascolari, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milano; 4Dipartimento di Immunologia Clinica e Medicina Interna, Scleroderma Unit - Fondazione IRCCS Ca' Granda Ospedale Maggiore, Milano, Italy; 5Owlstone Medical, Cambridge, UK
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PO:31:175 | Characterizing gastrointestinal involvement in systemic sclerosis: insights from the national systemic sclerosis progression investigation registry of the Italian Society of Rheumatology Francesco Bonomi1, Cosimo Bruni1|2, Silvia Laura Bosello3, Fabio Cacciapaglia4|5, Corrado Campochiaro6, Roberto Caporali7, Veronica Codullo8, Maria Antonietta D'Agostino3, Lorenzo Dagna6, Rossella De Angelis9, Giacomo De Luca6, Dilia Giuggioli10, Serena Guiducci1, Florenzo Iannone4, Francesca Ingegnoli7, Carlomaurizio Montecucco8, Valeria Riccieri11, Clodoveo Ferri10, Marco Matucci Cerinic6, Silvia Bellando Randone1. | 1Scleroderma Unit, Division of Rheumatology AOUC, and Department of Experimental and Clinical Medicine, Uni. of Florence, Firenze, Italy; 2Department of Rheumatology, University Hospital Zurich, University of Zurich Zurigo Switzerland; 3UOC of Rheumatology and Clinical Immunology, Catholic University of the Sacred Heart, Fondazione Policlinico A. Gemelli, Roma, Italy; 4Rheumatology Unit, Department of Emergency Surgery and Organ Transplantations, University of Bari, Bari, Italy; 5Rheumatology Service, F. Miulli General Hospital - Department of Medicine and Surgery, LUM 'G. De Gennaro', Casamassima, Italy; 6Unit of Immunology, Rheumatology, Allergy and Rare Diseases and Inflammation, fibrosis and ageing initiative, UniSR, Milano, Italy; 7Division of Clinical Rheumatology, ASST Pini and Università degli studi di Milano, Milano, Italy; 8Department of Rheumatology, Policlinico San Matteo, Pavia, Italy; 9Rheumatology Unit, Department of Clinical and Molecular Sciences, Polytechnic University of Marche, Ancona, Italy; 10Rheumatology Unit, School of Medicine, University of Modena and Reggio Emilia, Modena, Italy; 11Department of Rheumatology, Sapienza University of Rome, Roma, Italy.
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The diagnostic utility of miRNA21 in systemic sclerosis
992PDF: 124SUPPLEMENTARY MATERIAL: 33 -
PO:37:267 | Mimickers of polyarteritis nodosa: a case of segmental arteriolar mediolysis Filippo Santoro1, Caterina Vacchi2, Giulia Cassone2, Maria Grazia Malandra1, Dilia Giuggioli1|2 | 1UOSD Reumatologia, Ospedale San Camillo De Lellis, Rieti; 2UOC Igiene e Sanità Pubblica, ASL Rieti; 3Direzione Sanitaria, ASL Rieti, Italy
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PO:24:063 | Interstitial lung disease in idiopathic inflammatory myopathy patients: efficacy and safety of nintedanib Giulia Buonsante1|2|3, Giacomo De Luca1|2|3, Veronica Batani1|2, Lorenzo Dagna1|2|3, Marco Matucci-Cerinic1|2|3, Corrado Campochiaro1|2|3 | 1Unit of Immunology, Rheumatology, Allergy and Rare Diseases UNIRAR, IRCCS San Raffaele Hospital Milano, Italy; 2Inflammation, Fibrosis and aging Initiative INFLAGE, IRCCS San Raffaele Hospital Milano, Italy; 3Vita-Salute San Raffaele University, Milano, Italy
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PO:33:195 | Evaluation of prevalence and role of anti-endothelin type a-receptor and anti-angiotensin ii type 1-receptor antibodies in a cohort of systemic sclerosis patients Clara Minerba1, Sara Ferrigno1, Antonella Grimaldi2, Noemi Aprile3, Daniela Costanza2, Laura Quarta2, Maria Rita Ricciardi2, Daniela Stasi3, Paola Conigliaro1, Alberto Bergamini1, Eugenio Quarta2, Maria Sole Chimenti1. | 1U.O.C. Reumatologia, Dipartimento di Medicina dei Sistemi, Università di, Roma, Tor Vergata, Roma, Italy; 2U.O.S.D. Reumatologia, P.O. Vito Fazzi Lecce Italy; 3U.O.C. Patologia clinica e Microbiologia, P.O. Vito Fazzi Lecce Italy.
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PO:11:175 | Dermatomyositis and immunosuppressant treatment: a case of Staphylococcus aureus pneumonia in a hospitalized patient Simona Fichera1, Andrea Cito1, Martina Vigilia1, Maria Morrone1, Teresa Caferri1, Crescenzio Scioscia1, Simone Perniola1, Giuseppe Lopalco1, Florenzo Iannone1. | 1Unit of Rheumatology, Department of Precision and Regenerative Medicine, Area Jonica, University of Bari, Bari, Italy.
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PO:37:269 | Intensive therapeutic plasma exchange in life-threatening ANCA-associated vasculitis Davide Bertelle, Riccardo Bixio, Francesco Pollastri, Maurizio Rossini, Angelo Fassio, Alessandro Giollo | Unità di Reumatologia, Dipartimento di Medicina Clinica e Sperimentale, Università di Pisa
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