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CO:11:6 | Off-therapy remission in systemic lupus erythematosus: the BLys lupus flare index (BLyFI) as a decision tool for immunosuppressive therapy withdrawal in remitted patients Noemi Merra1, Anna Giorgia Osele1, Davide Ragno1, Greta Hulej1, Zahrà Rahmé1, Ilenia Anna Gennaio1, Filippo Vesentini1, Margherita Zen1, Luca Iaccarino1, Andrea Doria1 | Università degli Studi di Padova, Italy
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PO:34:204 | Impact of anti-centromere antibodies on immunosuppressive therapy persistence in systemic sclerosis: a single-center case-control study Martina Salerno1, Marius Cadar1, Ilaria Bisconti1, Francesca Romana Di Ciommo1, Elena Platania1, Jacopo Landro1, Beatrice De Girolamo1, Davide Mohammad Reza Beigi1|2, Simona Truglia1, Fabrizio Conti1, Valeria Riccieri1 | 1Rheumatology unit, AOU and Università di Cagliari; 2Asl Biella, Ospedale degli Infermi, Ponderano (BI), Italy
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PO:07:101 | Efficacy and safety of methotrexate in a cohort of patients affected by early-onset rheumatoid arthritis: a monocentric real-life study Carlo Cauli1, Martina Favretti2, Giulio Dolcini2, Vincenzo Ferraro1, Cristina Iannuccelli3, Fabrizio Conti1, Manuela Di Franco1 | 1UOC Reumatologia, Dipartimento di scienze cliniche internistiche anestesiologiche e cardiovascolari, Sapienza, Roma; 2Dipartimento di Medicina Molecolare, La Sapienza, Roma; 3UOC Reumatologia, AOU Policlinico Umberto I, La Sapienza, Roma, Italy
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PO:26:088 | Rheumatologic immune-related adverse events from immune checkpoint inhibitors: a monocentric retrospective study Giulio Fraticelli1|2, Nicola Farina1|2, Alessandro Tomelleri1|2, Marco Matucci Cerinic1|2, Corrado Campochiaro1|2, Lorenzo Dagna1|2. | 1Unit of Immunology, Rheumatology, Allergy and Rare Diseases UNIRAR, IRCCS San Raffaele Hospital, Milano, Italy; 2Inflammation, Fibrosis and Ageing Initiative INFLAGE, IRCCS San Raffaele Hospital, Milano, Italy.
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Evaluation of Th9 lymphocytes in peripheral blood of rheumatoid arthritis patients and correlation with anti-tumor necrosis factor therapy: results from an in vitro pivotal study
2092PDF: 1009IL RUOLO DEI LINFOCITI TH9 NELL'ARTRITE REUMATOIDE E NELLA RISPOSTA AL TRATTAMENTO CON INFLIXIMAB.: 624 -
PO:11:162 | DRESS syndrome: a case treated with mepolizumab Alessandro Belotti Masserini1, Stefania Bertocchi1, Eleonora Bruschi1, Silvia Breda1, Valeria Rossi1, Elide Lupi1, Tania Ubiali1, Fabrizio Angeli1, Massimiliano Limonta1 | 1ASST Papa Giovanni XXIII, Bergamo, Italy
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PO:18:264 | Anifrolumab in Systemic Lupus Erythematosus: Bridging Clinical Trial Data with Real-World Evidence Giulia Cassone2, Filippo Santoro1, Caterina Vacchi2, Dilia Giuggioli2, Chiara Cabassi1 | 1UOC Reumatologia, AOU Policlinico di Modena, Università degli studi di Modena e Reggio Emilia Modena e Reggio Emilia, Italy; 2UOC Reumatologia, AOU Policlinico di Modena Modena, Italy
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PO:14:199 | Preliminary data of a multicentric study on safety and efficacy of assisted reproductive techniques in pregnant women with systemic autoimmune diseases Valentina Canti1, Maria Bernadette Cilona1, Giuditta Gorgone1, Federica Pasi1, Antonia Calligaro2, Francesca Ruffilli3, Francesca Crisafulli6, Maria Tonello2, Eleonora Giacobbe4, Alba Chiara Pozzi6, Maria Chiara Gerardi4, Melissa Padovan3, Emanuele Bizzi5, Enrico Papaleo1, Beatrice Maranini3, Marcello Govoni3, Massimiliano Epis4, Angela Tincani6, Andrea Doria2, Patrizia Rovere Querini1 | 1IRCCS Ospedale San Raffaele and VitaSalute San Raffaele Milano, Italy; 2Rheumatology Unit, Departement of Medicine, University Hospital of Padua Padova, Italy; 3Rheumatology Unit, Azienda Ospedaliero Universitaria S. Anna Ferrara, Department of Medical Sciences, University of Fe Ferrara, Italy; 4ASST Grande Ospedale Metropolitano Niguarda Milano, Italy; 5Internal Medicine, Fatebenefratelli Hospital Milano, Italy; 6Rheumatology and Immunology Unit, ASST Spedali Civili Brescia e Università degli Studi di Brescia, Italy
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PO:24:068 | Case Report: ‘Spontaneous Pneumomediastinum in a Patient with MDA5-Positive Dermatomyositis and Severe Pulmonary Fibrosis’ Carlotta Braga1, Margherita Rizzo1, Marta Raschellà1, Beatrice Maranini1, Gioacchino Schifino2, Aldo Carnevale3, Marcello Govoni1, Andrea Lo Monaco1 | 1Rheumatology Unit, Department of Medical Sciences, University of Ferrara and Azienda Ospedaliero-Universitaria S. Anna Ferrara, Italy; 2Respiratory Medicine Unit, Department of Cardio-Thoracic-Vascular Pathologies, Arcispedale Sant'Anna, Ferrara, Italy; 3Radiology Unit, Department of Translational Medicine, University of Ferrara, Italy
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PO:14:197 | Safety of biologic and conventional immunosuppressants in an Italian cohort of patients with systemic lupus erythematosus: a longitudinal analysis from the Lupus Italian Registry pharmacoepidemiologic study promoted by the Italian Society of Rheumatology Davide Rozza1, Carlo Alberto Scirè1|2, Paola Conigliaro3, Giacomo Emmi4, Laura Coladonato6, Salvatore Scarpato7, Luca Iaccarino8, Serena Guiducci9, Giulia Pazzola10, Francesca Romana Spinelli11, Micol Frassi12, Ilaria Cavazzana12, Chiara Scirocco13, Valeria Orefice13, Immacolata Prevete13, Alessandra Bortoluzzi14, Marcello Govoni14, Elena Bartoloni15, Luca Moroni16, Giuseppe Alvise Ramirez16, Valentina Canti16, Giorgio Pettiti17, Maria Chiara Ditto18, Enrico Fusaro18, Marta Mosca19, Lorenzo Cavagna20, Fabrizio Conti11, Andrea Doria8, Gian Domenico Sebastiani13, Sperimentatori Gruppo Lire5 | 1Centro Studi della Società Italiana di Reumatologia, Milano; 2Dipartimento di Medicina e Chirurgia, Università degli Studi di Milano-Bicocca, Monza; 3Università di Roma Tor Vergata; 4Dipartimento di Scienze Mediche, Chirurgiche e della Salute, Università di Trieste; 5https://redcap.reumatologia.it/surveys/?s=LWL7WJM4KHDR97CC; 6Dip di Medicina di Precisione e Rigenerativa e area Jonica, Bari; 7Azienda Sanitaria Locale ASL Salerno; 8Università degli Studi di Padova; 9SOD Reumatologia, Dipartimento di Medicina Sperimentale e Clinica, Università degli Studi di Firenze; 10Arcispedale Santa Maria Nuova Reggio Emilia; 11Università degli Studi di Roma La Sapienza; 12Spedali Civili di Brescia; 13Azienda Ospedaliera San Camillo Forlanini, Roma; 14Azienda Ospedaliera Universitaria Sant'Anna, Ferrara; 15SC Reumatologia, Dipartimento di Medicina e Chirurgia, Università di Perugia; 16IRCCS Ospedale San Raffaele, Milano; 17Azienda Ospedaliera S. Croce e Carle, Cuneo; 18AOU Citta' della Salute e della Scienza di Torino; 19AOU Santa Chiara, Pisa; 20Università di Pavia, Italy
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PO:35:223 | Biologic therapy for sustained remission in eosinophilic myocarditis: real-world evidence from a tertiary center experience Federica Davanzo1, Caterina Menghi2, Andrea Silvio Giordani2, Anna Baritussio2, Federico Scognamiglio2, Cristina Vicenzetto2, Luca Iorio1, Renzo Marcolongo2, Cristina Basso3, Andrea Doria1, Roberto Padoan1, Alida Linda Patr Caforio2 | 1Rheumatology Unit, Department of Medicine, University of Padua Padova, Italy; 2Cardiology Unit, Department of Cardiac, Vascular, Thoracic Sciences and Public Health, University of Padua Padova, Italy; 3Cardiovascular Pathology, Department of Cardiac, Thoracic and Vascular Sciences and Public Health, University of Padua Padova, Italy
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PO:36:243 | Drug survival, discontinuation reasons and disease activity in patients with Behçet's disease treated with infliximab - a real-life study Antonello Sulis1, Federica Di Cianni1, Maria Laura Manca2, Rosaria Talarico1, Marta Mosca1. | 1Rheumatology Unit of Pisa, University of Pisa, Pisa, Italy, Pisa, Italy; 2Department of Clinical and Experimental Medicine and Department of Mathematics, University of Pisa, Italy, Pisa, Italy.
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PO:11:175 | Dermatomyositis and immunosuppressant treatment: a case of Staphylococcus aureus pneumonia in a hospitalized patient Simona Fichera1, Andrea Cito1, Martina Vigilia1, Maria Morrone1, Teresa Caferri1, Crescenzio Scioscia1, Simone Perniola1, Giuseppe Lopalco1, Florenzo Iannone1. | 1Unit of Rheumatology, Department of Precision and Regenerative Medicine, Area Jonica, University of Bari, Bari, Italy.
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PO:11:165 | Clinical mimicry and therapeutic challenge: A Case of Rapidly Progressive Mixed Connective Tissue Disease Elena Maria Di Virgilio1, Elisabetta Chessa2, Valentina Ibba2, Cosimina Matulli2, Jessica Sorgia1, Andrea Pace1, Matteo Piga1|2, Alberto Cauli1|2 | 1Università degli studi di Cagliari-Reumatologia, Cagliari, Italy; 2Struttura complessa di Reumatologia- AOU Cagliari, Cagliari, Italy
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PO:36:238 | Clinical, functional, and radiological similarities between interstitial lung disease–anti–myeloperoxidase and idiopathic pulmonary fibrosis Enrico Colombo1, Jessica Gozzi2, Paolo Francia3, Giulia Cervi2, Marilena Frigato1, Martina Garuti2, Francesca Bartoli1, Irene Gavioli1, Caterina Cerbone2, Massimiliano Beccaria2, Maria Teresa Costantino1 | 1SC Allergologia, Immunologia Clinica e Reumatologia, ASST Mantova; 2SC Pneumologia, ASST Mantova; 3SC Radiologia, ASST Mantova, Italy
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PO:22:038 | Recurrent Pneumonias and Persistent Inflammation in VEXAS Syndrome: The Role of BAL in Differential Diagnosis Francesco Ghellere1, Bernardo D'Onofrio1, Maria Chiara Ditto1, Salvatore Panaro1, Francesca Piccione1|2, Giacomo Tanti1, Enrico Fusaro1, Simone Parisi1 | 1SC Reumatologia, Città della Salute e della Scienza Torino, Italy; 2Fondazione Ricerca Molinette Torino, Italy
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PO:35:219 | Real-world effectiveness of mepolizumab on gastrointestinal involvement in eosinophilic granulomatosis with polyangiitis and hypereosinophilic syndrome: a multicentre retrospective study Alessia Gatti1, Francesca Regola1, Giulia Fontana1, Mario Addrea Piga2, Gianluca Moroncini2, Palma Carlucci3, Angelo Vacca3, Paolo Delvino4, Enrico Heffler5, Emanuele Nappi5, Jakub Moll6, Laura Losappio6, Jan Schroeder6, Federica Davanzo7, Roberto Padoan7, Edoardo Conticini8, Paolo Cameli8, Greta Pacini9, Alvise Berti9, Lorenzo Vrola10, Paola Tomietto10, Luca Quartuccio11, Jan Willem Cohen Tervaert12, Sabrina Arnold13, Peter Lamprecht13, Florence Roufosse14, Ilaria Cavazzana1, Franco Franceschini1, Giacomo Emmi15, Paola Toniati1. | 1Rheumatology and Clinical Immunology Unit, ERN ReCONNET, ASST Spedali Civili of Brescia and University of Brescia, Italy, Brescia, Italy; 2Università Politecnica delle Marche and Azienda Ospedaliero Universitaria delle Marche, Ancona, Italy, Ancona, Italy; 3Section of Internal Medicine 'Guido Baccelli', DiMePRe-J, University of Bari 'Aldo Moro', Bari, Italy, Bari, Italy; 4Rheumatology Unit, IRCCS San Gerardo dei Tintori, Monza, Italy Monza Italy; 5Department of Biomedical Sciences, Humanitas University and Personalized Medicine, Asthma and Allergy IRCCS Humanitas, Milano, Italy; 6Division of Allergy and Clinical Immunology, ASST GOM Niguarda, Milan, Italy, Milano, Italy; 7Rheumatology Unit, Department of Medicine DIMED, University of Padua, Padova, Italy, Padova, Italy; 8University of Siena, Siena, Italy, Siena, Italy; 9Santa Chiara Hospital and University of Trento, Unit of Rheumatology, Trento, Italy Trento Italy; 10UCO Medicina Clinica, ASUGI, Cattinara Teaching Hospital, Trieste, Italy, Trieste, Italy; 11Division of Rheumatology, Department of Medicine DMED, University of Udine, Udine, Italy, Udine, Italy; 12University of Alberta, Edmonton, Alberta, Canada and Maastricht University, Maastricht, The Netherlands Maastricht The Netherlands; 13Department of Rheumatology and Clinical Immunology, University of Lübeck, Lübeck, Germany Lubeck Germany; 14Department of Internal Medicine, Hôpital Universitaire de Bruxelles - Erasme, Université Libre de Bruxelles, Belgium Brussels Belgium; 15Clinical Medicine and Clinical Immunology and Rheumatology Unit Cattinara University Hospital and University of Trieste, Trieste, Italy.
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PO:33:202 | Assessment of Retinal Arteriolar Wall-to-Lumen Ratio and Renal Resistive Index in patients with Systemic Sclerosis Eleonora Pazzi1|2, Elda Piovani1|2, Claudia Barison1|2, Liala Moschetti1|2, Eleonora Pedretti1|2, Mariagrazia Lazzaroni1|2, Carolina De Ciuceis3, Claudia Agabiti-Rosei3, Giacomo Buso3|4, Paolo Baggi3, Claudia Rossini3, Cristina Bevacqua3, Maria Lorenza Muiesan3, Ilaria Cavazzana1, Franco Franceschini1, Paolo Airò2 | 1Rheumatology and Clinical Immunology, ASST Spedali Civili of Brescia, University of Brescia, Brescia, Italy; 2Scleroderma Unit, ASST Spedali Civili of Brescia, Brescia, Italy; 3Department of Clinical and Experimental Sciences, Division of Internal Medicine, ASST Spedali Civili of Brescia, Univers Brescia, Italy; 4University of Lausanne, Lausanne Switzerland
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PO:21:028 | A difficult case of VEXAS syndrome: management of myelodysplastic syndrome associated with systemic inflammation and infectious complications Sandra Lombardi1, Monica Regis1, Stefano De Luca1, Monica Poiani2, Rossella Stella2, Elisa Lucchini2, Francesco Zaja2, Fabio Fiammengo1 | 1SC Medicina Interna, Azienda Sanitaria Universitaria Giuliano Isontina, Gorizia; 2SC Ematologia, Azienda Sanitaria Universitaria Giuliano Isontina, Trieste, Italy
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PO:16:232 | Belimumab step-down dose spacing in patients with systemic lupus erythematosus in persistent clinical remission: experience from a multicentric cohort Alice Bartoletti1, Laura Giudice1, Lorenza Maria Argolini1|2, Giuseppe Alvise Ramirez3, Luca Moroni3, Tommaso Schioppo4, Chiara Bellocchi5|6, Annalaura Fasiello6, Lorenzo Beretta6, Lorenzo Dagna3, Roberto Caporali1, Maria Gerosa1. | 1UO Clinica Reumatologica, ASST Gaetano Pini CTO, Milano, Italy; 2UOC Medicina fisica e riabilitazione specialistica, ASST Gaetano Pini CTO, Milano, Italy; 3Unit of Immunology, Rheumatology, Allergy and Rare Diseases, IRCCS San Raffaele Hospital, Vita-Salute San Raffa Milano Italy; 4Medicina Generale II, Servizio di Reumatologia, Ospedale San Paolo, ASST Santi Paolo Carlo, Milano, Italy; 5Department of Clinical Sciences and Community Health, University of Milan, Dipartimeto di Eccellenza 2023-2027, Milano, Italy; 6Referral Centre for Systemic Autoimmune DIseases, Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico, Milano, Italy
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PO:10:144 | Management of pure red cell aplasia as the onset of systemic lupus erythematosus: a case report Chrystel Carolin Navarrete Cadena1, Marika Tardella1 | 1Università Politecnica delle Marche Jesi, Ancona, Italy
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PO:35:224 | Capturing What BVAS Misses: Patient-Reported Outcomes Reflect Disease Activity and Burden in EGPA Marta Codirenzi1, Federica Davanzo1, Luca Iorio1, Eleonora Fiorin1, Roberta Prevedello1, Roberto Padoan1, Andrea Doria1 | 1Unità di reumatologia, dipartimento di medicina DIMED,Università degli studi di Padova, Italy
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CO:01:4 | Identify predictors of relapse in idiopathic inflammatory myopathies: insights from an international cohort Cristina Bochicchio1|2, Maria Rosa Pellico1|2, Claudia Iannone1|2, Lekshmi Minikumari Rahulan3, Marco Fornaro4, Ilaria Cavazzana5, Edoardo Conticini6, Musataka Musataka7, Akira Yoshida7, Silvia Cavalli1|2, Silvia Grazzini6, Giulio Fraticelli8, Alessia Gatti5, Giulio Lopinto4, Paolo Semeraro5, Veronica Batani8, Thomas Patric Sheeran9, Florenzo Iannone4, Giacomo De Luca8, Roberto Caporali1|2, Latika Gupta9|10|11, Nicoletta Del Papa2. | 1Department of Clinical Sciences and Community Health, University of Milano; 2Department of Rheumatology and Medical Sciences, ASST Gaetano Pini-CTO Institute, Milano, Italy; 3Rheumatology "Sanjay Gandhi" Postgraduate Institute of Medical Sciences, Lucknow, Uttar Pradesh, India; 4Unit of Rheumatology, Department of Precision and Regenerative Medicine, Area Jonica, University of Bari; 5Rheumatology and Clinical Immunology Unit, ASST Spedali Civili di Brescia; 6Rheumatology Unit, Department of Medicine, Surgery and Neurosciences, University of Siena, Italy; 7Department of Allergy and Rheumatology Nippon Medical School Graduate School of Medicine, Tokyo, Japan; 8Unit of Immunology, Rheumatology, Allergy and Rare Diseases, IRCCS San Raffaele Hospital, Milano, Italy; 9Department of Rheumatology, Royal Wolverhampton Hospitals NHS Trust, Wolverhampton, UK; 10Francis Crick Institute, London, UK; 11School of Infection, Inflammation and Immunology, College of Medicine and Health, University of Birmingham, UK
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PO:01:008 | Active sacroiliitis at magnetic resonance enterography increases the risk of axial spondyloarthritis in Crohn’s disease patients, while greater age and disease duration are protective factors: a monocentric retrospective cohort study Gabriele Amati1, Gilda Sandri1|2, Giovanni Ciancio2, Benedetta Bongiovanni1|2, Martina Orlandi1|2, Ottavio Secchi1|2, Davide Vaccari3, Annarita Pecchi4, Angela Bertani5, Maddalena Pecchini5, Pietro Torricelli4, Antonio Colecchia5, Dilia Giuggioli1|2. | 1Struttura Complessa di Reumatologia, Azienda Ospedaliero-Universitaria Policlinico di Modena, Modena, Italy; 2Cattedra di Reumatologia, Università degli studi di Modena e Reggio Emilia, Modena, Italy; 3Unità Operativa di Radiologia, Ospedale di Pavullo, AUSL di Modena, Modena, Italy; 4Struttura Complessa di Radiologia, Azienda Ospedaliero-Universitaria Policlinico di Modena, Modena, Italy; 5Struttura Complessa di Gastroenterologia, Azienda Ospedaliero-Universitaria Policlinico di Modena, Modena, Italy.
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PO:16:240 | Systemic Lupus Erythematosus Presenting as End-Stage Liver Disease: A Case Report and Literature Review Annamaria Tiso1, Stefania Caccavelli1, Giuseppina Caroppi1, Candida Tarullo1, Gaetano Serviddio1 | 1Policlinico Riuniti Foggia, Italy
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PO:35:233 | Tocilizumab is associated with improved relapse-free survival in polymyalgia rheumatica: a multicentre retrospective study Milena Bond1, Giovanni Adami2, Marianna Tamussin3, Mario Frasca4, Sara Zandonella Callegher1, Marcello Govoni3, Maurizio Rossini2, Lorenzo Dagna4, Marco Matucci Cerinic4, Christian Dejaco1, Alessandro Tomelleri4 | 1Department of Rheumatology, Brunico Hospital ASAA-SABES, Teaching Hospital of the Paracelsius Medical University Bunico, Italy; 2Rheumatology Unit, University of Verona, Policlinico Borgo Roma Verona, Italy; 3Rheumatology Unit, Department of Medical Sciences, University of Ferrara and Azienda Ospedaliero-Universitaria S. Anna Ferrara, Italy; 4Unit of Immunology, Rheumatology, Allergy and Rare Diseases, IRCCS San Raffaele Hospital Milano, Italy
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PO:25:082 | Progressive interstitial lung disease secondary to Sjögren's disease in a patient with inclusion body myositis complicated by dysphagia: a multidisciplinary approach and therapeutic challenges Emanule Cocchiara1, Francesco Falco1, Lucia Spaggiari3, Francesca Cozzini1|2, Lucia Dardani1, Gianluigi Bajocchi1, Andreina Manfredi1|2, Carlo Salvarani1|2 | 1Dipartimento di Medicina, Clinica Reumatologica, Udine; 2Università degli studi di Modena e Reggio Emilia, Modena; 3AUSL area NORD, Guastalla-Montecchio, Italy
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CO:10:2 | Common variable immunodeficiency patients complicated by autoimmune and inflammatory rheumatic manifestations reveal high frequency of genetic variants potentially linked to inborn errors of immunity Paolo Semeraro1, Micol Frassi1, Silvia Clara Giliani2, Franco Franceschini1, Paolo Airò1. | 1Rheumatology and Clinical Immunology Unit, ERN ReCONNET, ASST Spedali Civili of Brescia and University of Brescia; 2Medical Genetic Laboratory, ASST Spedali Civili of Brescia and University of Brescia, Italy
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PO:16:227 | Anifrolumab for Systemic Lupus Erythematosus: Preliminary Safety and Efficacy Findings from the Italian Experience Paola Bizioli1|2, Chiara Orlandi1|2, Claudia Barison1|2, Cesare Tomasi3, Alessia Caproli1, Silvia Piantoni1|2, Simona Signorini4, Emirena Garrafa4, Cecilia Nalli1, Micol Frassi1, Ilaria Cavazzana1|2, Micaela Fredi1|2, Franco Franceschini1|2 | 1Rheumatology and Clinical Immunology Unit - ERN ReCONNET, ASST Spedali Civili of Brescia, Italy; 2Department of Clinical and Experimental Sciences, University of Brescia, Italy; 3Department of Clinical and Experimental Sciences, University of Brescia, Italy; 4Laboratory of Clinical Chemistry, Department of Molecular and Translational Medicine, University of Brescia, Italy
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PO:23:052 | Muscular and myocardial involvement in antisynthetase syndrome: a retrospective real-life study Giulia Buonsante1|2|3, Giacomo De Luca1|2|3, Veronica Batani1|2, Daniele Scaramuzzi1|2|3, Lorenzo Dagna1|2|3, Marco Matucci-Cerinic1|2|3, Corrado Campochiaro1|2|3. | 1Unit of Immunology, Rheumatology, Allergy and Rare Diseases UNIRAR, IRCCS San Raffaele Hospital, Milano, Italy; 2Inflammation, Fibrosis and aging Initiative INFLAGE, IRCCS San Raffaele Hospital, Milano, Italy; 3Vita-Salute San Raffaele University, Milan, Italy, Milano, Italy.
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