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PO:33:200 | Analysis of risk factors associated with vertebral fractures in systemic sclerosis: evidence from the "Sclero-RER" study group Alessandra Bezzi1, Federica Lumetti2, Martina Orlandi3, Fabio Mascella1, Maria Cristina Focherini1, Eugenio Arrigoni4, Elena Bravi4, Andrea Lo Monaco5, Amelia Spinella3, Ottavio Secchi3, Gianluigi Bajocchi6, Francesco Girelli7, Francesco Ursini8, Pierluigi Cataleta9, Massimo Reta10, Alarico Ariani11|12, Dilia Giuggioli3 | 1Internal Medicine and Rheumatology Unit, AUSL Romagna, Rimini 2AUSL of Modena and Rheumatology Unit, University Hospital Policlinico of Modena; 3Rheumatology Unit, University of Modena and Reggio Emilia; 4Rheumatology Unit, Guglielmo da Saliceto Hospital, Piacenza; 5Rheumatology, department of medical sciences, University of Ferrara; 6Rheumatology Unit, IRCCS Arcispedale Santa Maria Nuova Reggio Emilia; 7Rheumatology Unit, G.B. Morgagni - L. Pierantoni Hospital, Forlì; 8Rizzoli Orthopedic Institute, Rheumatology Unit, Department of Biomedical and Neuromotor Sciences, Alma Mater Studiorum Bologna; 9Hospital Santa Maria delle Croci, Rheumatology Unit, Department of Internal medicine, AUSL-Romagna Ravenna; 10Rheumatology Unit, AUSL of Bologna, Sant'Orsola Polyclinic Hospital, AOU IRCCS of Bologna; 11Internal Medicine and Rheumatology Unit, University Hospital of Parma; 12AUSL Bologna and University of Bologna, IRCCS Policlinico Sant'Orsola, Bologna, Italy
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PO:25:081 | Atypical onset of anti-SAE-1 positive dermatomyositis: paraneoplastic flame hemorrhages in urothelial carcinoma Valentina Morandi1, Alessandro Biglia2, Francesco Maggiore1, Sofia Chiricolo1, Silvia Sammorì1, Maria Cristina Sacchi3|4, Edoardo Cammarata5, Maria Rosa Pellico6, Luigi Mario Castello2|3|7. | 1Dipartimento di Medicina Interna, SSD Reumatologia, AOUAL Santi Antonio e Biagio e Cesare Arrigo, Alessandria, Italy; 2 Dipartimento di Medicina Interna, AOUAL Santi Antonio e Biagio e Cesare Arrigo, Alessandria, Italy; 3Dipartimento di laboratorio di tecnologia, ricerca e innovazione DAIRI, AOUAL Santi Antonio e Biagio e Cesare Arrigo, Alessandria, Italy; 4AOUAL Santi Antonio e Biagio e Cesare Arrigo, Laboratorio Analisi, Alessandria, Italy; 5AOUAL Santi Antonio e Biagio e Cesare Arrigo, Dipartimento di Medicina Interna, SSD Dermatologia, Alessandria, Italy; 6ASST Gaetano Pini, divisione di Reumatologia Clinica, Milano, Italy; 7Università del Piemonte orientale, dipartimento di Medicina Traslazione, Novara, Italy.
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CO:10:4 | Lung vasculature quantification on computed tomography predicts new onset of interstitial lung disease in systemic sclerosis Maria Iacovantuono1|2, Nicholas Landini2|3, Lisa Jungblut4, Gesa Sauer2, Rucsandra Dobrota2, Maria Sinziana Muraru-Carbune2, Muriel Elhai2, Carmen-Marina Mihai2, Mike Oliver Becker2, Maria Sole Chimenti1, Thomas Frauenfelder4, Anna-Maria Hoffmann-Vold5, Oliver Distler2, Cosimo Bruni2. | 1Rheumatology, Allergology and Clinical Immunology, Department of Systems Medicine, Tor Vergata University, Rome, Italy; 2Department of Rheumatology, University Hospital Zurich, University of Zurich, Switzerland; 3Department of Radiological Sciences, Oncology and Pathology, Sapienza University, Policlinico Umberto I, Rome, Italy; 4Institute for Diagnostic and Interventional Radiology, University Hospital Zurich, University Zurich, Switzerland; 5Department of Rheumatology, Oslo University Hospital, Norway
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PO:33:199 | Prevalence and clinical associations of antiphospholipid antibodies in patients with systemic sclerosis in the SPRING-SIR registry Antonio Tonutti1|2, Ilaria Cavazzana3, Angela Ceribelli1|2, Maria De Santis1|2, Giacomo De Luca4|5, Maria Grazia Lazzaroni3, Franco Franceschini3, Carlo Selmi1|2, Valeria Riccieri6, Silvia Laura Bosello7, Fabio Cacciapaglia8, Veronica Codullo9, Francesca Ingegnoli10, Dilia Giuggioli11, Rossella De Angelis12, Clodoveo Ferri11, Marco Matucci-Cerinic4|5 | 1Department of Biomedical Sciences, Humanitas Universityce Pieve Emanuele, Milan, Italy; 2Rheumatology and Clinical Immunology, IRCCS Humanitas Research Hospital Rozzano, Milan, Italy; 3Rheumatology and Clinical Immunology - ASST Spedali Civili Brescia - Department of Clinical and Experimental Sciences - Brescia, Italy; 4Vita-Salute San Raffaele University Milan, Italy; 5Unit of Immunology, Rheumatology, Allergy and Rare Diseases UnIRAR and INFLAGE Initiative, IRCCS San Raffaele Hospital Milan, Italy; 6University of Rome La Sapienza Rome, Italy; 7Catholic University of Sacred Heart Rome, Italy; 8LUM University Bari, Italy; 9Rheumatology Unit, Fondazione IRCCS Policlinico San Matteo Pavia, Italy; 10University of Milan Milan, Italy; 11University of Modena and Reggio Emilia Modena, Italy; 12Politechnic University of Marche Ancona, Italy
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PO:33:195 | Evaluation of prevalence and role of anti-endothelin type a-receptor and anti-angiotensin ii type 1-receptor antibodies in a cohort of systemic sclerosis patients Clara Minerba1, Sara Ferrigno1, Antonella Grimaldi2, Noemi Aprile3, Daniela Costanza2, Laura Quarta2, Maria Rita Ricciardi2, Daniela Stasi3, Paola Conigliaro1, Alberto Bergamini1, Eugenio Quarta2, Maria Sole Chimenti1. | 1U.O.C. Reumatologia, Dipartimento di Medicina dei Sistemi, Università di, Roma, Tor Vergata, Roma, Italy; 2U.O.S.D. Reumatologia, P.O. Vito Fazzi Lecce Italy; 3U.O.C. Patologia clinica e Microbiologia, P.O. Vito Fazzi Lecce Italy.
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Real-life effectiveness of rituximab in different subsets of idiopathic inflammatory myopathies
2505PDF: 694SUPPLEMENTARY MATERIAL: 355 -
PO:17:253 | Unveiling the gap: a multicenter study on factors driving patient-physician discrepancies in assessing disease activity in systemic lupus erythematosus Giorgia Ingrid Gozzoli1, Micaela Fredi1, Federica Bonaso1, Silvia Ebe Lucia Della Pina1, Claudia Barison1, Irene Lorenzini4, Raffaele Pericotti4, Anna Mattiuzzo4, Marcelo Neto2, Sofia Azevedo3, Cláudia Oliveira3, Cesare Tomasi4, Luís Sousa Inês2, Franco Franceschini1. | 1Rheumatology and Clinical Immunology Unit, ASST Spedali Civili of Brescia, Brescia, Italy; 2Rheumatology Department, Centro Hospitalar Universitário de Coimbra - ULS Coimbra, Coimbra, Portugal; 3Rheumatology Department, ULS Aveiro, Aveiro, Portugal; 4Department of Clinical and Experimental Sciences, University of Brescia, Brescia, Italy.
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PO:30:155 | The role of nailfold videocapillaroscopy in the assessment of juvenile connective tissue diseases Marco Binda1, Beatrice Moccaldi1, Francesca Tirelli2, Anna Cuberli1, Andrea Benini1, Meneghel Alessandra2, Andrea Doria1, Francesco Zulian2, Elisabetta Zanatta1 | 1U.O.C. Reumatologia, Dipartimento di Medicina DIMED, Università degli Studi di Padova Padova, Italy; 2U.O.S.D. Reumatologia Pediatrica, Dipartimento per la Salute della Donna e del Bambino, Azienda Ospedaliera di Padova, Italy
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PO:33:197 | Systemic sclerosis and endothelial dysfunction: the passive leg movement technique in the assessment of no-mediated vascular impairment Silvia Guella1, Giovanni Baldassarre3, Alessandro Gratton2|3, Lucrezia Zuccarelli3, Elena Treppo2, Emma Di Poi2, Bruno Grassi3, Luca Quartuccio2|3 | 1SS Reumatologia-CMID Ospedale San Giovanni Bosco, Torino; 2Clinica di Reumatologia Ospedale Santa Maria della Misericordia, ASUFC, Udine; 3Dipartimento di Medicina, Università di Udine, Italy
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PO:15:212 | Anifrolumab induces a rapid improvement in joint inflammation in Systemic Lupus Erythematosus patients: an ultrasonographic study Valeria Moretti, Fulvia Ceccarelli, Claudia Ciancarella, Valerio Fiorilli, Francesca Romana Spinelli, Fabrizio Conti | Sapienza Università di Roma, Italy
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PO:31:172 | Age and timing of onset of Raynaud's phenomenon and first non-Raynaud sign/symptom as prognostic factors in systemic sclerosis: a retrospective analysis from the systemic sclerosis progression investigation registry of the Italian Society for Rheumatology Silvia Peretti1, Cosimo Bruni2, Silvia Laura Bosello3, Fabio Cacciapaglia4-5, Corrado Campochiaro6-7, Veronica Codullo8, Lorenzo Dagna6-7, Rossella De Angelis9, Giacomo De Luca6-7, Dilia Giuggioli10, Serena Guiducci1, Florenzo Iannone4, Francesca Ingegnoli11, Valeria Riccieri12, Marco Matucci Cerinic6-7, Clodoveo Ferri10-13, Silvia Bellando Randone1. | 1Division of Rheumatology, Scleroderma Unit, Department of Experimental and Clinical Medicine, University of Florence, AO, Firenze, Italy; 2Division of Rheumatology, University Hospital Zurich, University of Zurich, Zurich, Switzerland; 3Rheumatology Division, Catholic University of the Sacred Heart, Fondazione Policlinico Universitario A. Gemelli- IRCCS, Roma, Italy; 4Rheumatology Unit, Department of Precision and Regenerative Medicine-Ionian Area, University of Bari Aldo Moro, Bari, Italy; 5Reumatology Service, Internal Medicine Unit F.Miulli General Hospital, Acquaviva delle Fonti -Department of Medicine a, Bari, Italy; 6Unit of Immunology, Rheumatology, Allergy and Rare Diseases UnIRAR, Inflammation, Fibrosis and Ageing initiative INFL, Milano, Italy; 7Vita-Salute San Raffaele University, Milano, Italy; 8Department of Internal Medicine and Therapeutics, Università di Pavia, Italy; Division of Rheumatology, Fondazione IRCCS, Pavia, Italy; 9Rheumatology Unit, Department of Clinical and Molecular Sciences, Polytechnic University of Marche, Ancona, Italy; 10Rheumatology Unit, School of Medicine, University of Modena and Reggio Emilia, Modena, Italy; 11Division of Clinical Rheumatology, ASST Pini, Dept. of Clinical Sciences and Community Health, Research Center for Adul, Milano, Italy; 12Department of Rheumatology, Sapienza University of Rome, Roma, Italy; 13Rheumatology Clinic Madonna dello Scoglio Crotonei, Crotone, Italy.
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PO:34:207 | When the Lungs Speak in Squeaks: Chronic Bird-Related HP in SSc-ILD with Incidental Lymphoma Mariagrazia Nuara1, Marco De Pinto2, Amelia Spinella2, Stefania Cerri1|2, Enrico Clini1|2, Dilia Giuggioli1|2 | 1Università degli Studi di Modena e Reggio Emilia, Italy; 2AOU, Policlinico di Modena, Italy
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PO:36:245 | Uncovering clinical and demographic differences in major organ involvement versus benign Behçet’s disease: insights from a single-centre study Federica Di Cianni1, Antonello Sulis1, Maria Laura Manca2, Rosaria Talarico1, Marta Mosca1. | 1Rheumatology Unit, University of Pisa, Pisa, Italy; 2Department of Clinical and Experimental Medicine and Department of Mathematics, University of Pisa, Pisa, Italy.
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CO:05:4 | Natural language processing reveals demographic features, comorbidities, and clinical domains to predict treatment longevity of b/tsDMARDs in psoriatic arthritis Antonio Tonutti1|2, Pierandrea Morandini3, Cosimo Faeti3, Nicoletta Luciano1|2, Saverio D'Amico3, Victor Savevski3, Carlo Selmi1|2 | 1Department of Biomedical Sciences, Humanitas University Pieve Emanuele, Milan, Italy; 2Rheumatology and Clinical Immunology, IRCCS Humanitas Research Hospital Rozzano, Milan, Italy; 3Artificial Intelligence Unit, IRCCS Humanitas Research Hospital Rozzano, Milan, Italy
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PO:31:167 | Increased M2 pro-fibrotic marker expression in circulating monocytes and cultured monocyte-derived macrophages in systemic sclerosis patients with progressive interstitial lung disease Vanessa Smith1|2, Stefano Soldano3, Rosanna Campitiello3|5, Emanuele Gotelli3|4, Paola Montagna3, Elvis Hysa3|5, Tamara Vojinovic3|4, Carmen Pizzorni3|4, Sabrina Paolino3|4, Alberto Sulli3|4, Maurizio Cutolo3|4. | 1Department of Internal Medicine and Department of Rheumatology, Ghent University Hospital, Ghent, Belgium; 2Unit for Molecular Immunology and Inflammation, VIB Inflammation Research Centre, Ghent, Belgium; 3Laboratory of Experimental Rheumatology and Academic Division of Clinical Rheumatology, Department of Internal Medicine, Genova, Italy; 4IRCCS Ospedale Policlinico San Martino, Genova, Italy; 5Department of Experimental Medicine DIMES, University of Genova, Genova, Italy.
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PO:15:222 | Post-hoc analysis of the BeRLiSS-JS registry: efficacy of belimumab on thrombocytopenia Greta Hulej1, Margherita Zen1, Marisol Bracalenti1, Francesca Bottazzi2, Rossella De Angelis3, Giacomo Emmi4, Roberto Gerli5, Marcello Govoni6, Renato Lo Gullo7, Simone Negrini8, Luca Quartuccio9, Maurizio Rossini10, Carlo Salvarani11, Paola Tomietto4, Angelo Vacca12, Andrea Doria1, Luca Iaccarino1. | 1Università degli Studi di Padova, Padova, Italy; 2Università degli Studi di Pavia, Pavia, Italy; 3Università Politecnica delle Marche, Ancona, Italy; 4Università degli Studi di Trieste, Trieste, Italy; 5Università degli Studi Perugia, Perugia, Italy; 6Università degli Studi di Ferrara, Ferrara, Italy; 7Università degli Studi di Catania, Catania, Italy; 8Università degli Studi di Torino, Torino, Italy; 9Università degli Studi di Udine, Udine, Italy; 10Università degli Studi di Verona, Verona, Italy; 11Università degli Studi di Modena e Reggio Emilia, Modena, Italy; 12Università degli Studi di Bari .
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CO:03:3 | Contribution of mitochondrial DNA to the onset and maintenance of inflammation in Systemic Sclerosis patients Martina Orlandi1, Giorgia Sinigaglia2, Amelia Spinella1, Isabella Martusciello2, Marco De Pinto1, Giorgia Roveta1, Luca Keller1, Marcello Pinti2, Dilia Giuggioli1 | 1Dipartimento di scienze mediche e chirurgiche dei bambini e degli adulti, Università di Modena e Reggio Emilia, Italy; 2Università degli Studi di Modena e Reggio Emilia, Italy
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PO:16:235 | Anifrolumab in systemic lupus erythematosus: real-life experience of a single-center cohort Filippo Vesentini1, Luca Iaccarino1, Federico Arru2, Greta Hulej1, Anna Giorgia Osele1, Noemi Merra1, Davide Ragno1, Andrea Doria1, Margherita Zen1 | 1UOC Reumatologia, Dipartimento di Medicina DIMED, Università degli Studi di Padova; 2UO Medicina, ASL 3 Nuoro, Italy
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PO:11:165 | Clinical mimicry and therapeutic challenge: A Case of Rapidly Progressive Mixed Connective Tissue Disease Elena Maria Di Virgilio1, Elisabetta Chessa2, Valentina Ibba2, Cosimina Matulli2, Jessica Sorgia1, Andrea Pace1, Matteo Piga1|2, Alberto Cauli1|2 | 1Università degli studi di Cagliari-Reumatologia, Cagliari, Italy; 2Struttura complessa di Reumatologia- AOU Cagliari, Cagliari, Italy
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PO:24:068 | Case Report: ‘Spontaneous Pneumomediastinum in a Patient with MDA5-Positive Dermatomyositis and Severe Pulmonary Fibrosis’ Carlotta Braga1, Margherita Rizzo1, Marta Raschellà1, Beatrice Maranini1, Gioacchino Schifino2, Aldo Carnevale3, Marcello Govoni1, Andrea Lo Monaco1 | 1Rheumatology Unit, Department of Medical Sciences, University of Ferrara and Azienda Ospedaliero-Universitaria S. Anna Ferrara, Italy; 2Respiratory Medicine Unit, Department of Cardio-Thoracic-Vascular Pathologies, Arcispedale Sant'Anna, Ferrara, Italy; 3Radiology Unit, Department of Translational Medicine, University of Ferrara, Italy
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PO:10:155 | Etanercept-induced lupus in a patient with rheumatoid arthritis: diagnostic challenges and multidisciplinary therapeutic approach Camilla Riboldi1|2, Claudia Iannone1|2, Maria Gerosa1|2, Roberto Felice Caporali1|2 | 1ASST G. Pini-CTO, U.O.C. di Clinica Reumatologica, Milano; 2Dipartimento di Scienze Cliniche e di Comunità, Università degli Studi di Milano, Italy
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PO:06:081 | Safety of JAK inhibitors compared to non-TNF-targeted biologic therapies in rheumatoid arthritis patients who are inadequate responders to TNF inhibitors Lorenzo Di Luozzo1, Alessandro Giollo1, Mariangela Salvato1, Francesca Frizzera1, Kiren Khalid1, Margherita Zen1, Andrea Doria1 | 1Azienda ospedaliera universitaria di Padova, unità di Reumatologia, Padova, Italy
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