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PO:31:165 | Prevalence and incidence of skin telangectasia and their association with clinical features: analysis of the European Scleroderma Trials and Research cohort Gemma Lepri1, Lorenzo Tofani2, Silvia Bellando Randone1, Veronica Batani3, Paolo Airò4, Patricia Carreira5, Joerg Henes6, Alexandra Balbir Gurman7, Florenzo Iannone8, Antonella Marcoccia9, Luc Mouthon10, Branimir Anic11, Carolina De Souza Müller12, Armine Haroyan13, Ana Cristina Cordeiro14, Serena Guiducci And Eustar Coll1. | 1University of Florence, Dept of Experimental and Clinical Medicine, AOU Careggi, Division of Rheumatology Florence Italy; 2University of Florence, Dept of Statistics, Informatics, Applications, Florence, Italy; 3Unit of Immunology, Rheumatology, Allergy and Rare Diseases UnIRAR, IRCCS San Raffaele, Milano, Italy; 4Scleroderma Unit, UOC Rheumatology and Clinical Immunology, ASST Spedali Civili, Brescia, Italy; 5Dept of Rheumatology, 12 de Octubre University Hospital, Madrid, Spain; 6Centre for Interdisciplinary Rheumatology, Immunology and autoimmune diseases INDIRA, University Hospital Tuebingen, Tuebingen, Germany; 7Rheumatology Institute, Rambam Health Care Campus Haifa Israel; 8Dept of Precision and Regenerative Medicine and Ionian Area, University of Bari, Bari, Italy; 9Interdisciplinary Reference Center for Systemic Sclerosis CRIIS Sandro Pertini Hospital, Rome, Italy; 10Dept of Internal Medicine, Cochin Hospital, Paris Cité University, Paris, France; 11Div Clinical Immunology and Rheumatology, Dept Internal Medicine, School of Medicine, University Hospital Center Zagreb, Zagreb, Croatia; 12Rheumatology Division, Hospital de Clínicas da Universidade Federal do Parana, Curitiba, Brazil; 13Dept of Rheumatology, Yerevan State Medical University of Armenia, Yerevan, Armenia; 14Servico Reumatologia Hospital Garcia de Orta Almada, Almada, Portugal.
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PO:02:018 | After-SECs: clinical predictors of secukinumab retention in psoriatic arthritis patients with inadequate response to anti-tumor necrosis factor therapy Francesco Cristiano1, Davide Gaspare Patti1, Valentina Boni1, Stefano Di Murro1, Cesare Gavotti1, Roberta Masnata1, Giulia Calabrese2, Gerlando Natalello2, Giusy Peluso2, Augusta Ortolan1|2, Enrico De Lorenzis1|2, Maria Antonietta D'Agostino1|2. | 1Università Cattolica del Sacro Cuore, Roma, Italy; 2Divisione di Reumatologia ed Immunologia clinica, Fondazione Policlinico Universitario A. Gemelli IRCCS, Roma, Italy.
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PO:15:215 | Evaluating the Prognostic Value of Modified NIH Indices and Total Renal Chronicity Score in Lupus Nephritis: a single center retrospective analysis Alessandra Ida Celia1, Andrea Ascione2, Bruna Cerebelli2, Martina Leopizzi2, Cristiano Alessandri1, Francesca Romana Spinelli1, Fabrizio Conti1 | 1Reumaologia, Scienze Cliniche internistiche, anestesiologiche e cardiovascolari, Università La Sapienza di Roma, Italy; 2Anatomia patologica, Dipartimento di Scienze biotecnologiche medico-chirurgiche, Università La Sapienza di Roma, Italy
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PO:32:185 | Deep-learning analysis of high-resolution computed tomography images predicts progression and mortality in systemic sclerosis related interstitial lung disease Valentina Boni1, Rosa D'Abronzo2, Piergiacomo Cerasuolo1, Lucio Calandriello2, Giuseppe Cicchetti2, Gerlando Natalello1, Bruno Iovene5, Francesco Varone5, Giacomo Sgalla5, Luca Richeldi5, Anna Rita Larici2|4, Maria Antonietta D'Agostino1|3, Silvia Laura Bosello1|3, Enrico De Lorenzis1. | 1Division of Rheumatology and Clinical Immunology Catholic Univeristy of the Sacred Heart, Rome, Italy; 2Department of Diagnostic Imaging, Oncological Radiotherapy and Hematology, Diagnostic Imaging Area, Catholic University, Rome, Italy; 3Department of Geriatric and Orthopaedic Sciences, Catholic Univeristy of the Sacred Heart, Rome, Italy; 4Department of Radiological and Hematological Sciences, Section of Radiology, Catholic Univeristy of the Sacred Heart, Rome, Italy; 5Division of Pulmonary Medicine, Catholic University of the Sacred Heart, Roma, Italy.
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S02:6 | Monocyte-Driven Inflammation and Inflammasome Activation in ANCA-Positive EGPA: Evidence of Persistent Immune Activation During Remission Chiara Baggio1, Luca Iorio1, Carlotta Boscaro2|3, Federica Davanzo1, Marta Tonello1, Mattia Albiero4, Andrea Doria1, Paolo Sfriso1, Roberto Padoan1, Francesca Oliviero1 | 1Rheumatology Unit, Department of Medicine, University of Padova, Italy; 2Department of Medicine, University of Padova, Italy; 3Veneto Institute of Molecular Medicine, Laboratory of Experimental Diabetology, Italy; 4Department of Surgery, Oncology, and Gastroenterology, University of Padova, Italy
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PO:08:113 | Shaping rheumatoid arthritis treatment: clinical and demographic drivers of tsDMARDs versus bDMARDs prescription post-EMA pronouncement on JAK inhibitors - insights from the AMBI-RA study Riccardo Bertola1, Beatrice Maranini1, Carlo Garaffoni1, Maria Pozzuto1, Anna Laura Riva Cambrino1, Alessandro Spinelli1, Letizia Mamprin1, Federico Agostini1, Martina Di Nunzio1, Marcello Govoni1, Alessandra Bortoluzzi1, Ettore Silvagni1 | 1Rheumatology Unit, Department of Medical Sciences, University of Ferrara and Azienda Ospedaliero-Universitaria S. Anna, Italy
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PO:24:068 | Case Report: ‘Spontaneous Pneumomediastinum in a Patient with MDA5-Positive Dermatomyositis and Severe Pulmonary Fibrosis’ Carlotta Braga1, Margherita Rizzo1, Marta Raschellà1, Beatrice Maranini1, Gioacchino Schifino2, Aldo Carnevale3, Marcello Govoni1, Andrea Lo Monaco1 | 1Rheumatology Unit, Department of Medical Sciences, University of Ferrara and Azienda Ospedaliero-Universitaria S. Anna Ferrara, Italy; 2Respiratory Medicine Unit, Department of Cardio-Thoracic-Vascular Pathologies, Arcispedale Sant'Anna, Ferrara, Italy; 3Radiology Unit, Department of Translational Medicine, University of Ferrara, Italy
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PO:07:108 | Achievement of Treatment Targets and Maintenance of Response with Upadacitinib in Patients with Moderate-to-Severe Rheumatoid Arthritis in a Real-world Setting: Final 2-year Outcomes from the UPHOLD Study Enrico Marchetta1, Andrew Östör2|8, Eugen Feist3, Prodromos Sidiropoulos4, Jérôme Avouac5, Martin Rebella6|7, Rajaie Namas9, Erin Mcdearmon Blondell10, Ivan Lagunes10, Tianming Gao10, Tim Shaw10, Suzan Attar11 | 1AbbVie Srl Roma, Italy; 2Monash University and Emeritus Research, Melbourne, Victoria, Melbourne, Australia; 3Helios Department of Rheumatology and Clinical Immunology, Vogelsang-Gommern, Vogelsang Gommern, Germany; 4Faculty of Medicine, University of Crete, Heraklion, Heraklion, Greece; 5Service de Rhumatologie, Hôpital Cochin, AP HP Centre Université Paris Cité, Parigi, France; 6Departamento de Medicina, Facultad de Medicina, Universidad de la República, Montevideo, Montevideo, Uruguay; 7Unidad de Enfermedades Autoinmunes Sistémicas, MUCAM, Montevideo, Montevideo, Uruguay; 8Australian National University, Camberra, Australia; 9Medical Subspecialties Institute, Division of Rheumatology, Cleveland Clinic Abu Dhabi, United Arab Emirates; 10AbbVie Inc., North Chicago, Illinois, United States of America Chicago, USA; 11King Abdulaziz University, Jeddah, Saudi Arabia
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PO:31:166 | S'/PAPs ratio in systemic sclerosis: a promising non-invasive index for early detection and prognosis of pulmonary hypertension. A step toward more accurate screening? Marco De Pinto1, Amelia Spinella1, Pierluca Macripò2, Alessia Laneri1, Benedetta Bongiovanni1, Maria Grazia Malandra1, Martina Orlandi1-3, Gianluca Pagnoni2, Arianna Maini2, Rosario Rossi2-4, Clodoveo Ferri1, Francesca Coppi2-3, Dilia Giuggioli1-3. | 1Rheumatology Unit, Azienda Ospedaliero-Universitaria Policlinico di Modena, University of Modena and Reggio Emilia, Modena, Italy; 2Cardiology Division, Azienda Ospedaliero-Universitaria Policlinico di Modena, Modena, Italy; 3Department of Medical and Surgical Sciences for Children and Adults, University of Modena and Reggio Emilia, Modena, Italy; 4Department of Biomedical, Metabolic and Neural Sciences, University of Modena and Reggio Emilia, Modena, Italy.
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PO:12:180 | Echocardiographic screening of pulmonary hypertension in a multidisciplinary cohort of patients with interstitial lung disease Lorenzo Mattia Bianchessi1, Veronica Piccin1, Federica Sabatelli1, Lorenzo Cavagna1, Giovanni Zanframundo1, Domenicafederica Briganti2, Mauro Acquaro3, Stefano Ghio3, Domenico Sorace1, Valentina Vertui2, Ilaria Giana2, Andrea Patanè3, Veronica Codullo1 | 1UOC Reumatologia, Fondazione IRCCS Policlinico S. Matteo, Pavia; 2Centro Trapianti, Fondazione IRCCS Policlinico San Matteo, Pavia; 3UOC Cardiologia, Fondazione IRCCS Policlinico San Matteo, Pavia, Italy
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PO:08:119 | Infusional Advantage: Rituximab’s Role in Enhancing Adherence in Multimorbid Rheumatoid Arthritis Marco Capodiferro1, Daniele Domanico1, Angelica Napoletano1, Giulia Righetti2, Patrizia Suppressa2, Vincenzo Venerito1, Giuseppe Lopalco1, Florenzo Iannone1, Fabio Cacciapaglia1|2 | 1Rheumatology Unit, Department of Precision and Regenerative Medicine and Jonian Area DiMePRe-J University of Bari, Italy; 2Department of Medicine and Surgery, Miulli General Hospital Acquaviva delle Fonti - LUM University Casamassima Bari Acquaviva delle Fonti, Bari, Italy
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PO:31:171 | Uncovering subclinical cardiac involvement in VEDOSS: An echocardiographic driven study Eugenio Capparelli1, Eleonora Zaccara1, Irene Rota2, Sara Facetti2, Daniela Bompane1, Laura Castelnovo1, Antonino Mazzone3, Paola Faggioli1 | 1UOC Reumatologia, ASST Ovest-Milanese, Legnano Milano Italy; 2UOC Cardiologia, ASST Ovest-Milanese, Legnano Milano, Italy; 3UOC Medicina Interna, ASST Ovest-Milanese, Legnano, Milano, Italy
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PO:11:165 | Clinical mimicry and therapeutic challenge: A Case of Rapidly Progressive Mixed Connective Tissue Disease Elena Maria Di Virgilio1, Elisabetta Chessa2, Valentina Ibba2, Cosimina Matulli2, Jessica Sorgia1, Andrea Pace1, Matteo Piga1|2, Alberto Cauli1|2 | 1Università degli studi di Cagliari-Reumatologia, Cagliari, Italy; 2Struttura complessa di Reumatologia- AOU Cagliari, Cagliari, Italy
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PO:28:127 | Efficacy of b/ts-DMARDS therapy on depressive and anxiety symptoms in patients with chronic inflammatory joint diseases: preliminary results of a prospective study Nikita Pecani1, Christian D'Elia1, Francesca Bartoli1, Sabrina Aliberti1, Francesco Rotella2, Arianna Ida Altomare2, Francesco Vinci2, Lorenzo Cortoni2, Davide Benedetti3, Camilla Ferrari4, Gemma Lepri1, Silvia Bellando Randone1, Serena Guiducci1 | 1SOD Reumatologia, Dipartimento di Medicina Sperimentale e Clinica, Università degli Studi di Firenze; 2Unità di Psichiatria, Dipartimento di Scienze della Salute, Università degli Studi di Firenze; 3Dipartimento Salute Mentale, USL Umbria, Città di Castello (PG); 4Scuola di Scienze della Salute Umana - Università degli Studi di Firenze, Italy
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PO:06:088 | Are all Difficult-To-Treat RA patients the same? Insights into clinical features and drug discontinuation Silvia Di Noto1, Cristina Garufi1, Letizia Caruso1, Fulvia Ceccarelli1, Cristiano Alessandri1, Federica Ucci1, Valerio Fiorilli1, Fabrizio Conti1, Francesca Romana Spinelli1 | 1Sapienza University of Rome, Dipartimento di Scienze Cliniche Internistiche, Anestesiologiche e Cardiovascolari, Roma, Italy
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PO:14:200 | Placental markers of angiogenesis in pregnant women with antiphospholipid syndrome: predictive role of SFLT-1, PLGF, and uterine artery doppler in preeclampsia Maria Bernadette Cilona1, Valentina Canti1, Martina Beschi2, Federica Pasi3, Serena Girardelli3, Mirko Pozzoni3, Maria Teresa Castiglioni3, Paolo Cavoretto3, Patrizia Rovere-Querini1|2 | 1Unit of Internal Medicine and Division of Immunology, Transplantation and Infectious diseases, IRCCS San Raffaele Hospital Milan, Italy; 2Vita-Salute San Raffaele University Milan, Italy; 3Department of Obstetrics and Gynecology, IRCCS San Raffaele Scientific Institute Milan, Italy
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PO:06:078 | Is difficult-to-treat rheumatoid arthritis less severe in patients with autoantibody-negative disease? retrospective analysis from a monocentric cohort. Bernardo D'Onofrio1, Maria Chiara Ditto1, Francesco Ghellere1, Giacomo Tanti1, Salvatore Panaro1, Enrico Fusaro1, Simone Parisi1. | 1AOU Città della Salute e della Scienza, Torino, Italy.
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PO:02:019 | Incidence of Spondyloarthritis in a Cohort of Italian patients presenting with Acute Non-granulomatous Anterior Uveitis during a five-years follow-up period Alessandra Rai1, Niccolò Possemato1|2, Giorgia Citriniti2, Filippo Crescentiini2, Marianna Oliva2, Elena Bolletta3, Pietro Gentile3, Luca De Simone3, Fabrizio Gozzi3, Luca Cimino1|3, Pierluigi Macchioni2, Carlo Salvarani1|2 | 1Università di Modena e Reggio Emilia Modena, Italy; 2Unità di Reumatologia, Azienda USL-IRCCS Reggio Emilia, Reggio Emilia, Italy; 3Unità di Immunologia Oculare, Azienda USL-IRCCS Reggio Emilia, Reggio Emilia, Italy
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CO:08:2 | Impact of comorbidities on clinical-serological phenotype of primary Sjögren's disease: a retrospective analysis of a multicenter cohort Roberto Dal Pozzolo1, Maria Letizia Currò2, Giacomo Cafaro1, Valeria Manfrè3, Gaetano La Rocca4, Alessia Alunno5, Francesco Carubbi5, Nicoletta Del Papa6, Viktoriya Pavlych7, Ilenia Fischetti8, Letizia Pia Di Corcia9, Pamela Bernardini10, Luca Quartuccio3, Chiara Baldini4, Paola Cipriani7, Roberta Priori8, Onorina Berardicurti9, Serena Guiducci10, Serena ColaFrancesco11, Fabiola Atzeni2, Elena Bartoloni1. | 1SC Reumatologia. Università di Perugia; 2Unità di Reumatologia. Università di Messina; 3Unità di Reumatologia, Università di Udine; 4Unità di Reumatologia. Università di Pisa; 5Divisione di Medicina Interna e Nefrologia. Università di L'Aquila; 6Dipartimento di Reumatologia. Università di Milano; 7Unità di Reumatologia, Università di L'Aquila; 8UOC Reumatologia. Università Sapienza, Roma; 9Unità di Reumatologia. Università Campus Biomedico, Roma; 10Unità di Reumatologia. Università di Firenze; 11Reumatologia e Immunologia Clinica. IRCCS Humanitas, Milano, Italy
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PO:32:178 | Effectiveness of oral anticoagulants in precapillary pulmonary hypertension associated with systemic sclerosis: a EUSTAR cohort study Nicola Farina1, Silvia Bellando-Randone1, Hilde Jenssen-Bjørkekjær2, David Launay3, Patricia Carreira4, Paolo Airò5, Serena Guiducci1, Dilia Giuggioli6, Gabriela Riemekasten7, Carmen-Pilar Simeón Aznar8, Christina Bergmann9, Elise Siegart10, Ivan Castellví11, Lesley Ann Saketkoo12, Jeska De Vries-Bouwstra13, Philipp Klemm14, Ulf Müller-Ladner14, Alexandra Balbir-Gurman15, Vanessa Smith16, Florenzo Iannone17, Luca Idolazzi18, Christopher Denton19, Edoardo Rosato20, Britta Maurer1, Yannick Allanore1, Yoshiya Tanaka1, Elisabetta Zanatta1, Oliver Distler1, Marco Matucci-Cerinic1, Cosimo Bruni1 | 1Department of Experimental and Clinical Medicine, Scleroderma Unit, Division of Rheumatology, University of Florence, Az Firenze, Italy; 2Department of Rheumatology, Hospital of Southern Norway Kristiansand, Norway; 3National Reference Center for Pulmonary Arterial Hypertension Pulmotension Lille, France; 4Hospital Universitario 12 de Octubre, Rheumatology Department Madrid Spain; 5ASST Spedali Civili of Brescia, University of Brescia, Rheumatology and Clinical Immunology Unit Brescia, Italy; 6Scleroderma Unit, Rheumatology Unit, University Hospital of Modena and Reggio Emilia Modena, Italy; 7Universitätsklinikum Schleswig-Holstein, Klinik für Rheumatologie und klinische Immunologie Lübeck Germany; 8Hospital Universitario Vall d'Hebron, Department of Internal Medicine, Systemic Autoimmune Diseases Unit Barcelona Spain; 9University Hospital Erlangen, Department Internal Medicine 3 Erlangen Germany; 10Charité University Hospital, Department of Rheumatology Berlin Germany; 11Hospital de la Santa Creu i Sant Pau Baercelona Spain; 12New Orleans Scleroderma and Sarcoidosis Patient Care and Research Center New Orleans, USA; 13Leiden University Medical Center, Department of Rheumatology Leiden, The Netherlands; 14JLU Giessen, Campus Kerckhoff, Department of Rheumatology and Clinical Immunology Center Bad Nauheim Germany; 15Rambam Health Care Campus, Rheumatology Institute Haifa, Israel; 16University of Ghent, Department of Rheumatology Ghent, Belgium; 17Rheumatology DiMePReJ, University of Bari, School of Medicine Bari, Italy; 18University of Verona, Section of Rheumatology, Department of Medicine Verona, Italy; 19Royal Free London and University College London Medical School, Centre for Rheumatology London, United Kingdom; 20Sapienza University of Rome, Department of Translational and Precision Medicine Azienda Ospedaliero-Universitaria Policl Roma, Italy
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PO:10:144 | Management of pure red cell aplasia as the onset of systemic lupus erythematosus: a case report Chrystel Carolin Navarrete Cadena1, Marika Tardella1 | 1Università Politecnica delle Marche Jesi, Ancona, Italy
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PO:12:178 | Don't count your chickens before they hatch! Analysis of cardiovascular definitions in studies on rheumatic diseases: a systematic literature review Laura Pezzoni1, Silvia Sirotti1|2, Georgios Filippou1|2, Piercarlo Sarzi Puttini1|2, Greta Pellegrino1|2. | 1Università degli Studi di Milano, Milano; 2IRCCS Ospedale Galeazzi Sant'Ambrogio, Milano, Italy.
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PO:35:226 | Red flags raising suspicion of Eosinophilic Granulomatosis with Polyangiitis (EGPA): results from the European EGPAware Delphi study Gabriele Brembilla1, Bernhard Hellmich2|3, Apostolos Bossios4|5, Chistian Domingo-Ribas6|7, Giacomo Emmi8, Cristina Ponte9|10, Maria Roser Solans-Laque11, Íñigo Jesus Rúa-Figueroa12, Augusto Vaglio13, Dimitrios Vassilopoulos14, Konstantina Kallinikou15, Benjamin Terrier16 | 1GSK Verona, Italy; 2Medius Klinik Kirchheim Kirchheim unter Teck Germany; 3Teaching Hospital of the University of Tübingen Tübingen Germany; 4Karolinska University Hospital Stockholm, Sweden; 5Karolinska Institutet Solna, Sweden; 6Parc Taulí University Hospital. Parc Taulí Research and Innovation Institute I3PT-CERCA Barcelona Spain; 7Department of Medicine, Universitat Autònoma de Barcelona UAB Barcelona Spain; 8University of Trieste, UNITS, Trieste, Italy; 9Santa Maria Hospital Lisbon, Portugal; 10Lisbon Academic Medical Center Lisbon, Portugal; 11Vall d'Hebron University Hospital Barcelona Spain; 12Gran Canaria Doctor Negrín Hospital Las Palmas de Gran Canaria Spain; 13University of Florence Florence, Italy; 14National and Kapodistrian University of Athens School of Medicine Athens, Greece; 15GSK Athens, Greece; 16Cochin Hospital Paris, France
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