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CO:10:1 | High-grade synovitis and histological pathotype distribution in patients with advanced osteoarthritis undergoing joint replacement: a more inflammatory disease than we thought? Jacopo Ciaffi1, Lorenzo Bianchi1, Luana Mancarella2, Federica Pignatti2, Veronica Brusi2, Lucia Lisi2, Simona Neri2, Elisa Assirelli2, Alberto Righi3, Marco Gambarotti3, Francesco Ursini1. | 1SSD Medicina e Reumatologia, IRCCS Istituto Ortopedico Rizzoli, Alma Mater Studiorum Università di Bologna; 2SSD Medicina e Reumatologia, IRCCS Istituto Ortopedico Rizzoli, Bologna; 3SSD di Anatomia e Istologia Patologica, IRCCS Istituto Ortopedico Rizzoli, Bologna, Italy
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PO:06:082 | Correlation between ultrasonographic parameters and the Krenn synovitis score in patients with chronic infiammatory arthropathy undergoing ultrasound-guided synovial biopsy: a prospective cohort study Maria Capita1, Carlo Garaffoni1, Marianna Tamussin1, Serena Ceccato1, Giovanni Lanza2, Alessandra Bortoluzzi1, Marcello Govoni1, Ettore Silvagni1 | 1Unità di Reumatologia, Azienda Ospedaliero - Universitaria S. Anna, Cona (FE); 2Anatomia Patologica, Dipartimento di Medicina Traslazionale Università di Ferrara, Cona (FE), Italy
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PO:06:093 | Clinical and ultrasound phenotyping comparison between Difficult-To-Treat Rheumatoid Arthritis (D2TRA) and non-D2TRA patients: experience from a monocentric cohort Silvia Perrone1, Claudio Cruciani1, Silvia Mascolo1, Elisa Bellis1, Gloria Crepaldi1, Valeria Data1, Claudia Garulli1, Claudia Lomater1, Elena Marucco1, Marta Saracco1, Mariele Gatto1, Annamaria Iagnocco1. | 1Academic Rheumatology Centre, Department of Clinical and Biological Sciences, University of Turin, AO Mauriziano, Turin, Italy.
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PO:09:134 | The impact of intra-articular hyaluronic acid injections on osteoarthritis synovitis: a study on synovial tissue of total knee arthroplasty patients Orazio De Lucia1, Laura Giudice1|2, Carolina Artusi1, Luca Ingrao1|2, Giorgia Trignani1|2, Matteo Ferrito1, Andrea Amati1|2, Marta Arese1|2, Camilla Riboldi1|2, Isabella Scotti1, Antonella Murgo1, Ennio Giulio Favalli1|2, Antonina Parafioriti3, Elisabetta Armiraglio3, Andrea Di Bernardo3, Filippo Calanna4, Chiara Fossati4, Pietro Simone Randelli4|5, Roberto Felice Caporali1|2 | 1Dipartimento di Reumatologia e Scienze Mediche,ʁSST Centro Specialistico Ortopedico Traumatologico Gaetano Pini-CTO, Milano; 2Dipartimento di Scienze Cliniche e di Comunità, Università degli Studi di Milano; 3UOC Anatomia Patologica, ASST Centro Specialistico Ortopedico Traumatologico Gaetano Pini-CTO, Milano; 4UOC 1° Clinica Ortopedica, ASST Centro Specialistico Ortopedico Traumatologico Gaetano Pini-CTO, Milano; 5Università degli Studi di Milano, Dipartimento di Scienze Biomediche per la Salute, Milano, Italy
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PO:02:017 | Difficult-to-treat psoriatic arthritis: clinical and ultrasonographic predictors in a real-life cohort Federico Favaro1, Elisa Bellis1, Claudio Cruciani1, Gloria Crepaldi1, Valeria Data1, Claudia Garulli1, Claudia Lomater1, Elena Marucco1, Marta Saracco1, Mariele Gatto1, Annamaria Iagnocco1. | 1Academic Rheumatology Centre, Departement of Clinical and Biological Sciences, University of Turin, AO Mauriziano, Torino, Italy.
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CO:07:5 | Enhanced fibroblast signatures in females with early rheumatoid arthritis highlights a potential basis for poorer treatment outcomes Benedetta Monosi1, James Perera2, Alessandra Nerviani2|3, Maria Sole Chimenti1, Felice Rivellese2|3, Costantino Pitzalis2|3|4. | 1Rheumatology, Allergology and Clinical Immunology, Department of Systems Medicine, University of Rome Tor Vergata, Rome, Italy; 2Centre for Experimental Medicine and Rheumatology, William Harvey Research Institute, Queen Mary University of London, London, UK; 3Barts Health NHS Trust and Barts Biomedical Research Centre, National Institute for Health and Care Research, London, UK; 4Department of Biomedical Sciences Humanitas University and IRCCS Humanitas Research Hospital, Milano, Italy
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PO:06:094 | Exploring the relationship between inflammation and collagen deposition in synovial tissue and clinical outcomes in active arthritis: insights from a monocentric pilot study Dario Bruno1, Barbara Tolusso1, Daniela Renna1, Mohamed Hegazi2, Fabio Pasqualini2, Marta Caprioli1, Giacomo Maria Guidelli1, Tommaso Hubert3, Nicoletta Luciano1|3, Marzia Monferini3, Natasa Isailovic3, Fabio Grizzi2|3, Salvatorelorenzo Renne3, Costantino Pitzalis1|3|4, Elisa Gremese1|3. | 1Rheumatology and Clinical Immunology, IRCCS Humanitas Research Hospital, Rozzano (MI); 2Department of Immunology and Inflammation, IRCCS Humanitas Research Hospital, Milano; 3Department of Biomedical Sciences, Humanitas University, Rozzano (MI), Italy; 4Centre for Experimental Medicine and Rheumatology, Queen Mary University of London, London, UK
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PO:05:066 | Atypical diagnosis and manifestation of spondyloarthritis: a case report Adele Del Giudice1, Filippo Crescentini2, Giorgia Citriniti2, Luca Cimino1|3, Carlo Salvarani1|2 | 1Department of Rheumatology, Università Cattolica del Sacro Cuore, Fondazione Policlinico Universitario A. Gemelli IRCCS, Roma, Italy; 2Department of Medicine, University of Melbourne at St Vincent's Hospital Melbourne, Australia; 3Department of Rheumatology, Division of Medicine, University College, London, UK
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S07:5 | Ankle ultrasound patterns may in the identification of Löfgren’s syndrome in patients with acute-onset erythema nodosum Davide Corradini1, Alberto Floris1, Andrea Carta2, Mattia Congia1, Elisabetta Chessa1, Matteo Piga1, Alberto Cauli1. | 1Rheumatology Unit, AOU and University of Cagliari, Cagliari, Italy; 2Department Economics and Business, University of Cagliari, Cagliari, Italy.
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CO:10:3 | Clinical response to JAK inhibitors or non-TNFi-targeted biologicals according to synovial tissue characteristics in patients with difficult-to-treat rheumatoid arthritis Mariangela Salvato1, Alessandro Giollo1, Francesca Frizzera1, Kiren Khalid1, Lorenzo Di Luozzo1, Maria Capita1, Marianna Tamussin1, Carlo Garaffoni2, Marny Fedrigo3, Annalisa Angelini3, Ettore Silvagni2, Andrea Doria1. | 1Rheumatology Unit, Department of Medicine - DIMED, University of Padova; 2Rheumatology Unit, Department of Medical Sciences, University of Ferrara and Azienda Ospedaliero-Universitaria S. Anna; 3Cardiovascular Pathology, Department of Cardiac, Thoracic, Vascular Sciences and Public Health, University of Padova, Italy
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PO:26:097 | Ultrasound evaluation of temporomandibular disorders: comparative analysis between inflammatory and degenerative patterns in patients with and without rheumatological pathologies Beatrice Maranini1, Stefano Mandrioli2, Fabio Fabbian3, Tommaso Bianchi1, Manlio Galiè2, Marcello Govoni1 | 1UO di Reumatologia, Dipartimento di Scienze Mediche, Università di Ferrara; 2UO di Chirurgia Maxillo-Facciale, Dipartimento Testa-Collo, Università di Ferrara; 3Dipartimento di Scienze Mediche, Università di Ferrara, Italy
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PO:04:061 | Higher prevalence of baseline comorbidities in patients developing difficult to treat psoriatic arthritis Mario Ferraioli1, Michelina Turri1, Eneida Çela1, Mauro Fatica1, Paola Conigliaro1, Elisabetta Greco1, Alberto Bergamini1, Maria Sole Chimenti1. | 1Rheumatology, Allergology and Clinical Immunology, Department of Systems Medicine, University of Rome, Tor Vergata, Rome, Italy.
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