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CO:10:1 | High-grade synovitis and histological pathotype distribution in patients with advanced osteoarthritis undergoing joint replacement: a more inflammatory disease than we thought? Jacopo Ciaffi1, Lorenzo Bianchi1, Luana Mancarella2, Federica Pignatti2, Veronica Brusi2, Lucia Lisi2, Simona Neri2, Elisa Assirelli2, Alberto Righi3, Marco Gambarotti3, Francesco Ursini1. | 1SSD Medicina e Reumatologia, IRCCS Istituto Ortopedico Rizzoli, Alma Mater Studiorum Università di Bologna; 2SSD Medicina e Reumatologia, IRCCS Istituto Ortopedico Rizzoli, Bologna; 3SSD di Anatomia e Istologia Patologica, IRCCS Istituto Ortopedico Rizzoli, Bologna, Italy
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PO:06:082 | Correlation between ultrasonographic parameters and the Krenn synovitis score in patients with chronic infiammatory arthropathy undergoing ultrasound-guided synovial biopsy: a prospective cohort study Maria Capita1, Carlo Garaffoni1, Marianna Tamussin1, Serena Ceccato1, Giovanni Lanza2, Alessandra Bortoluzzi1, Marcello Govoni1, Ettore Silvagni1 | 1Unità di Reumatologia, Azienda Ospedaliero - Universitaria S. Anna, Cona (FE); 2Anatomia Patologica, Dipartimento di Medicina Traslazionale Università di Ferrara, Cona (FE), Italy
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PO:06:093 | Clinical and ultrasound phenotyping comparison between Difficult-To-Treat Rheumatoid Arthritis (D2TRA) and non-D2TRA patients: experience from a monocentric cohort Silvia Perrone1, Claudio Cruciani1, Silvia Mascolo1, Elisa Bellis1, Gloria Crepaldi1, Valeria Data1, Claudia Garulli1, Claudia Lomater1, Elena Marucco1, Marta Saracco1, Mariele Gatto1, Annamaria Iagnocco1. | 1Academic Rheumatology Centre, Department of Clinical and Biological Sciences, University of Turin, AO Mauriziano, Turin, Italy.
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PO:02:017 | Difficult-to-treat psoriatic arthritis: clinical and ultrasonographic predictors in a real-life cohort Federico Favaro1, Elisa Bellis1, Claudio Cruciani1, Gloria Crepaldi1, Valeria Data1, Claudia Garulli1, Claudia Lomater1, Elena Marucco1, Marta Saracco1, Mariele Gatto1, Annamaria Iagnocco1. | 1Academic Rheumatology Centre, Departement of Clinical and Biological Sciences, University of Turin, AO Mauriziano, Torino, Italy.
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PO:09:134 | The impact of intra-articular hyaluronic acid injections on osteoarthritis synovitis: a study on synovial tissue of total knee arthroplasty patients Orazio De Lucia1, Laura Giudice1|2, Carolina Artusi1, Luca Ingrao1|2, Giorgia Trignani1|2, Matteo Ferrito1, Andrea Amati1|2, Marta Arese1|2, Camilla Riboldi1|2, Isabella Scotti1, Antonella Murgo1, Ennio Giulio Favalli1|2, Antonina Parafioriti3, Elisabetta Armiraglio3, Andrea Di Bernardo3, Filippo Calanna4, Chiara Fossati4, Pietro Simone Randelli4|5, Roberto Felice Caporali1|2 | 1Dipartimento di Reumatologia e Scienze Mediche,ʁSST Centro Specialistico Ortopedico Traumatologico Gaetano Pini-CTO, Milano; 2Dipartimento di Scienze Cliniche e di Comunità, Università degli Studi di Milano; 3UOC Anatomia Patologica, ASST Centro Specialistico Ortopedico Traumatologico Gaetano Pini-CTO, Milano; 4UOC 1° Clinica Ortopedica, ASST Centro Specialistico Ortopedico Traumatologico Gaetano Pini-CTO, Milano; 5Università degli Studi di Milano, Dipartimento di Scienze Biomediche per la Salute, Milano, Italy
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CO:07:5 | Enhanced fibroblast signatures in females with early rheumatoid arthritis highlights a potential basis for poorer treatment outcomes Benedetta Monosi1, James Perera2, Alessandra Nerviani2|3, Maria Sole Chimenti1, Felice Rivellese2|3, Costantino Pitzalis2|3|4. | 1Rheumatology, Allergology and Clinical Immunology, Department of Systems Medicine, University of Rome Tor Vergata, Rome, Italy; 2Centre for Experimental Medicine and Rheumatology, William Harvey Research Institute, Queen Mary University of London, London, UK; 3Barts Health NHS Trust and Barts Biomedical Research Centre, National Institute for Health and Care Research, London, UK; 4Department of Biomedical Sciences Humanitas University and IRCCS Humanitas Research Hospital, Milano, Italy
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PO:06:094 | Exploring the relationship between inflammation and collagen deposition in synovial tissue and clinical outcomes in active arthritis: insights from a monocentric pilot study Dario Bruno1, Barbara Tolusso1, Daniela Renna1, Mohamed Hegazi2, Fabio Pasqualini2, Marta Caprioli1, Giacomo Maria Guidelli1, Tommaso Hubert3, Nicoletta Luciano1|3, Marzia Monferini3, Natasa Isailovic3, Fabio Grizzi2|3, Salvatorelorenzo Renne3, Costantino Pitzalis1|3|4, Elisa Gremese1|3. | 1Rheumatology and Clinical Immunology, IRCCS Humanitas Research Hospital, Rozzano (MI); 2Department of Immunology and Inflammation, IRCCS Humanitas Research Hospital, Milano; 3Department of Biomedical Sciences, Humanitas University, Rozzano (MI), Italy; 4Centre for Experimental Medicine and Rheumatology, Queen Mary University of London, London, UK
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PO:05:066 | Atypical diagnosis and manifestation of spondyloarthritis: a case report Adele Del Giudice1, Filippo Crescentini2, Giorgia Citriniti2, Luca Cimino1|3, Carlo Salvarani1|2 | 1Department of Rheumatology, Università Cattolica del Sacro Cuore, Fondazione Policlinico Universitario A. Gemelli IRCCS, Roma, Italy; 2Department of Medicine, University of Melbourne at St Vincent's Hospital Melbourne, Australia; 3Department of Rheumatology, Division of Medicine, University College, London, UK
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PO:07:098 | Reasons for treatment failure and their synovial correlate among patients with difficult-to-treat rheumatoid arthritis Alessandro Giollo1, Mariangela Salvato1, Francesca Frizzera1, Kiren Khalid1, Lorenzo Di Luozzo1, Carlo Garaffoni2, Maria Capita2, Marianna Tamussin2, Giovanni Lanza2, Marny Fedrigo3, Annalisa Angelini3, Roberta Ramonda1, Ettore Silvagni2, Andrea Doria1 | 1UOC Reumatologia Padova, Italy; 2UOC Reumatologia Ferrara, Italy; 3UOC Patologia cardiovascolare Padova, Italy; 4UOC Anatomia Patologica Ferrara, Italy
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PO:01:001 | Clinical and histopathological features of refractory psoriatic arthritis undergoing ultrasound-guided synovial biopsy: comparison between non-inflammatory and persistent inflammatory profiles Marianna Tamussin1, Carlo Garaffoni1, Maria Capita1, Serena Ceccato1, Giovanni Lanza2, Mariangela Salvato3, Kiren Khalid3, Francesca Frizzera3, Lorenzo Di Luozzo3, Annalisa Angelini4, Roberta Ramonda3, Alessandra Bortoluzzi1, Andrea Doria3, Marcello Govoni1, Alessadro Giollo3, Ettore Silvagni1 | 1Rheumatology Unit, Department of Medical Sciences, University of Ferrara and Azienda Ospedaliero-Universitaria S. Anna Ferrara, Italy; 2Pathology Unit, Department of Translational Medicine, University of Ferrara, Ferrara Ferrara, Italy; 3Rheumatology Unit, Department of Medicine , DIMED, University of Padua Padova, Italy; 4Cardiovascular Pathology, Department of Cardiac, Thoracic, Vascular Sciences and Pulic Health, University of Padua, Padova, Italy
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PO:07:107 | Performance of the 2010 ACR/EULAR classification criteria for Rheumatoid Arthritis in a group of elderly onset patients Alessandra Rai1, Pierluigi Macchioni1, Giovanni Barausse2, Luigi Boiardi1, Giuseppe Paolazzi2, Carlo Salvarani1, Andreina Manfredi1 | 1University of Modena and Reggio Emilia, USL-IRCCS Reggio Emilia, Italy; 2Rheumatology Unit, Ospedale di Trento, Italy
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PO:04:061 | Higher prevalence of baseline comorbidities in patients developing difficult to treat psoriatic arthritis Mario Ferraioli1, Michelina Turri1, Eneida Çela1, Mauro Fatica1, Paola Conigliaro1, Elisabetta Greco1, Alberto Bergamini1, Maria Sole Chimenti1. | 1Rheumatology, Allergology and Clinical Immunology, Department of Systems Medicine, University of Rome, Tor Vergata, Rome, Italy.
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S07:5 | Ankle ultrasound patterns may in the identification of Löfgren’s syndrome in patients with acute-onset erythema nodosum Davide Corradini1, Alberto Floris1, Andrea Carta2, Mattia Congia1, Elisabetta Chessa1, Matteo Piga1, Alberto Cauli1. | 1Rheumatology Unit, AOU and University of Cagliari, Cagliari, Italy; 2Department Economics and Business, University of Cagliari, Cagliari, Italy.
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PO:21:018 | The role of rheumatologists in the diagnosis and monitoring of Whipple's disease Mariangela Salvato1, Alessandro Giollo1, Marco Cola2, Francesca Frizzera1, Kiren Khalid1, Lorenzo Di Luozzo1, Annamaria Cattelan2, Andrea Doria1 | 1UOC Reumatologia, AOUI Padova, Italy; 2UOC Malattie infettive, AOUI Padova, Italy
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CO:10:3 | Clinical response to JAK inhibitors or non-TNFi-targeted biologicals according to synovial tissue characteristics in patients with difficult-to-treat rheumatoid arthritis Mariangela Salvato1, Alessandro Giollo1, Francesca Frizzera1, Kiren Khalid1, Lorenzo Di Luozzo1, Maria Capita1, Marianna Tamussin1, Carlo Garaffoni2, Marny Fedrigo3, Annalisa Angelini3, Ettore Silvagni2, Andrea Doria1. | 1Rheumatology Unit, Department of Medicine - DIMED, University of Padova; 2Rheumatology Unit, Department of Medical Sciences, University of Ferrara and Azienda Ospedaliero-Universitaria S. Anna; 3Cardiovascular Pathology, Department of Cardiac, Thoracic, Vascular Sciences and Public Health, University of Padova, Italy
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PO:15:212 | Anifrolumab induces a rapid improvement in joint inflammation in Systemic Lupus Erythematosus patients: an ultrasonographic study Valeria Moretti, Fulvia Ceccarelli, Claudia Ciancarella, Valerio Fiorilli, Francesca Romana Spinelli, Fabrizio Conti | Sapienza Università di Roma, Italy
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PO:26:097 | Ultrasound evaluation of temporomandibular disorders: comparative analysis between inflammatory and degenerative patterns in patients with and without rheumatological pathologies Beatrice Maranini1, Stefano Mandrioli2, Fabio Fabbian3, Tommaso Bianchi1, Manlio Galiè2, Marcello Govoni1 | 1UO di Reumatologia, Dipartimento di Scienze Mediche, Università di Ferrara; 2UO di Chirurgia Maxillo-Facciale, Dipartimento Testa-Collo, Università di Ferrara; 3Dipartimento di Scienze Mediche, Università di Ferrara, Italy
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