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PO:35:222 | Distinctive Features of Localized Vasculitis of the Gastrointestinal Tract Compared to Takayasu Arteritis: Insights from a Multicenter Cohort Study Vittorio Dibenedetto1|2|3, Alessandro Tomelleri1|2, Corrado Campochiaro1|2, Elena Baldissera1|2, Luca Moroni1|2, Padoan Roberto4, Marco Matucci-Cerinic1|2|3, Lorenzo Dagna1|2|3 | 1Unit of Immunology, Rheumatology, Allergy and Rare Diseases UNIRAR, IRCCS San Raffaele Hospital Milan, Italy; 2Inflammation, Fibrosis and Ageing Intitiative INFLAGE, IRCCS San Raffaele Hospital Milan, Italy; 3Vita-Salute San Raffaele University, Milan, Italy Milan, Italy; 4University Hospital of Padova, Department of Internal Medicine and Rheumatology Padova, Italy
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PO:33:195 | Evaluation of prevalence and role of anti-endothelin type a-receptor and anti-angiotensin ii type 1-receptor antibodies in a cohort of systemic sclerosis patients Clara Minerba1, Sara Ferrigno1, Antonella Grimaldi2, Noemi Aprile3, Daniela Costanza2, Laura Quarta2, Maria Rita Ricciardi2, Daniela Stasi3, Paola Conigliaro1, Alberto Bergamini1, Eugenio Quarta2, Maria Sole Chimenti1. | 1U.O.C. Reumatologia, Dipartimento di Medicina dei Sistemi, Università di, Roma, Tor Vergata, Roma, Italy; 2U.O.S.D. Reumatologia, P.O. Vito Fazzi Lecce Italy; 3U.O.C. Patologia clinica e Microbiologia, P.O. Vito Fazzi Lecce Italy.
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PO:21:018 | The role of rheumatologists in the diagnosis and monitoring of Whipple's disease Mariangela Salvato1, Alessandro Giollo1, Marco Cola2, Francesca Frizzera1, Kiren Khalid1, Lorenzo Di Luozzo1, Annamaria Cattelan2, Andrea Doria1 | 1UOC Reumatologia, AOUI Padova, Italy; 2UOC Malattie infettive, AOUI Padova, Italy
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PO:03:033 | Low Uveitis Rates in Patients with Axial Spondyloarthritis or Psoriatic Arthritis Treated with Bimekizumab: Long-Term Results from Phase 2b/3 Trials Irene E Van Der Horst-Bruinsma1, Matthew A Brown2, Floris A Van Gaalen3, Nigil Haroon4, Lianne S Gensler5, Alexander Marten6, Myriam Manente7, George Stojan8, Thomas Vaux9, Katy White9, Atul Deodhar10, Nicola Boffini11, Martin Rudwaleit12 | 1Department of Rheumatology, Radboud University Medical Centre Nijmegen, The Netherlands; 2Genomics England London, United Kingdom; 3Department of Rheumatology, Leiden University Medical Center Leiden, The Netherlands; 4Department of Medicine/Rheumatology, University Health Network, Schroeder Arthritis Institute, University of Toronto Toronto, Canada; 5Department of Medicine/Rheumatology, University of California San Francisco, USA; 6UCB Monheim am Rhein Germany; 7UCB Braine-lAlleud, Belgium; 8UCB Atlanta, USA; 9UCB Slough, United Kingdom; 10Division of Arthritis and Rheumatic Diseases, Oregon Health and Science University Portland, USA; 11IRCCS Ospedale San Raffaele Milan, Italy; 12Klinikum Bielefeld, University of Bielefeld, Bielefeld, Germany
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PO:16:236 | Achieving a low disease activity state with a corticosteroid dose of 5 mg or less: observational study with anifrolumab in patients with systemic lupus erythematosus in Italy Alessandra Bortoluzzi1, Fulvia Ceccarelli2, Fabio Leo3, Paola Roccatagliata3, Chiara Tani4, Margherita Zen5 | 1Azienda Ospedaliera Universitaria Sant' Anna di Cona, Università di Ferrara Italy; 2Unità di Reumatologia, Università Sapienza Roma Italy; 3AstraZeneca S.p.a. Milano Italy; 4Università di Pisa e Azienda Ospedaliero Universitaria Pisana, Pisa Italy; 5Dipartimento di Medicina DIMED , Divisione di Reumatologia, Università di Padova, Italy
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PO:35:223 | Biologic therapy for sustained remission in eosinophilic myocarditis: real-world evidence from a tertiary center experience Federica Davanzo1, Caterina Menghi2, Andrea Silvio Giordani2, Anna Baritussio2, Federico Scognamiglio2, Cristina Vicenzetto2, Luca Iorio1, Renzo Marcolongo2, Cristina Basso3, Andrea Doria1, Roberto Padoan1, Alida Linda Patr Caforio2 | 1Rheumatology Unit, Department of Medicine, University of Padua Padova, Italy; 2Cardiology Unit, Department of Cardiac, Vascular, Thoracic Sciences and Public Health, University of Padua Padova, Italy; 3Cardiovascular Pathology, Department of Cardiac, Thoracic and Vascular Sciences and Public Health, University of Padua Padova, Italy
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PO:02:024 | Development of anti-drug antibodies in patients with peripheral and/or axial spondyloarthritis treated with infliximab or adalimumab: a monocentric cross-sectional study Gabriele Amati1, Gilda Sandri1|2, Alessandra Melegari3, Benedetta Bongiovanni1|2, Giovanni Ciancio2, Martina Orlandi1|2, Ottavio Secchi1, Dilia Giuggioli1|2 | 1Struttura complessa di Reumatologia, Azienda Ospedaliero-Universitaria Policlinico di Modena; 2Cattedra di Reumatologia, Università degli studi di Modena e Reggio Emilia; 3Dipartimento di medicina di laboratorio, Ospedale di Baggiovara, AUSL di Modena, Italy
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PO:18:271 | Managing concomitant sle and psoriasis: the role of anifrolumab in a clinical case Angela Carenza1, Liliana Dinoia2, Sergio De Gioia2, Federica Gatti1, Teresa Caferri1, Lucia Cristiana Colaprico1, Angelica Napoletano1, Giuseppe Lopalco1, Florenzo Iannone1. | 1Rheumatology Unit, University of Bari, Department of Precision and Regenerative Medicine, Jonian area DiMePRe-J, Bari, Italy; 2Azienda Sanitaria Locale di Taranto, presidio ospedaliero SS. Annunziata, Unità Operativa di Reumatologia, Taranto, Italy.
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PO:22:032 | Beyond the joints: a rare case of subcorneal pustular dermatosis in Rheumatoid Arthritis Sara Casella1|2, Carlo Smirne1|2, Roberta Zaira Pedrazzoli3, Mattia Perazzi1|3, Edoardo Cammarata4, Francesca Zottarelli4, Paola Savoia5, Renzo Boldorini6, Mario Pirisi1|2, Pier Paolo Sainaghi1|3 | 1Dipartimento di Medicina Traslazionale, Università del Piemonte Orientale Novara, Italy; 2Unità di Medicina Interna, Azienda Ospedaliera Maggiore della Carità Novara, Italy; 3Unità di Medicina Interna e Reumatologia, Azienda Ospedaliera Maggiore della Carità Novara, Italy; 4Unità di Dermatologia, Azienda Ospedaliera Maggiore della Carità Novara, Italy; 5Dipartimento di Scienze della salute, Università del Piemonte Orientale Novara, Italy; 6Unità di Anatomia Patologica, Azienda Ospedaliera Maggiore della Carità Novara, Italy
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PO:03:037 | The Impact of Peripheral Joint Involvement, Pain, and Inflammatory Bowel Diseases on Drug Persistence in Axial Psoriatic Arthritis Giuseppe Lopalco1, Sergio Del Vescovo1, Maria Sole Chimenti2, Giuliana Guggino3, Serena Guiducci4, Eleonora Celletti5, Alberto Cauli6, Luca Cantarini7, Valentino Paci8, Eneida Cela2, Lidia La Barbera3, Gemma Lepri4, Myriam Di Penta5, Alberto Floris6, Alice Agostinelli8, Vincenzo Venerito1, Michele Maria Luchetti8, Florenzo Iannone1 | 1Rheumatology Unit, Department of Precision and Regenerative Medicine and Ionian Area, Bari, Italy; 2Reumatology, Allergology and Clinical Immunology University of Rome Tor Vergata, Roma, Italy; 3Department of Health Promotion Sciences, Maternal and Infant Care, Internal Medicine and Medical Specialties, Palermo, Italy; 4Divisions of Internal Medicine and Rheumatology AOUC, Department of Experimental and Clinical Medicine, Firenze, Italy; 5Rheumatology Unit, SS. Annunziata Hospital of Chieti, G. D'Annunzio, Chieti, Italy; 6Department of Medical Science and Public Health, Cagliari, Italy; 7Policlinico Le Scotte, Siena, Italy; 8Clinical Medicine, Dipartimento di Scienze Cliniche e Molecolari, Università Politecnica delle Marche, Ancona, Italy
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PO:21:028 | A difficult case of VEXAS syndrome: management of myelodysplastic syndrome associated with systemic inflammation and infectious complications Sandra Lombardi1, Monica Regis1, Stefano De Luca1, Monica Poiani2, Rossella Stella2, Elisa Lucchini2, Francesco Zaja2, Fabio Fiammengo1 | 1SC Medicina Interna, Azienda Sanitaria Universitaria Giuliano Isontina, Gorizia; 2SC Ematologia, Azienda Sanitaria Universitaria Giuliano Isontina, Trieste, Italy
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PO:31:163 | Safety and tolerability of home-based prostacyclin analogue therapy in vascular manifestations of the scleroderma spectrum: results of a monocentric study Alice Dionisi1, Lucrezia Verardi2, Annacarla Finucci2, Paola Volpe2, Anna Cinzia Raspa2, Paola Cipriani1, Raffaele Zicolella2 | 1Reumatologia,Dipartimento di Sscienze Cliniche Applicate e Biotecnologiche, Università degli Studi dell'Aquila; 2UOC Reumatologia, Ospedale Civile di Pescara, Italy
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PO:16:235 | Anifrolumab in systemic lupus erythematosus: real-life experience of a single-center cohort Filippo Vesentini1, Luca Iaccarino1, Federico Arru2, Greta Hulej1, Anna Giorgia Osele1, Noemi Merra1, Davide Ragno1, Andrea Doria1, Margherita Zen1 | 1UOC Reumatologia, Dipartimento di Medicina DIMED, Università degli Studi di Padova; 2UO Medicina, ASL 3 Nuoro, Italy
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PO:14:202 | Use of anifrolumab in the treatment of the hematological manifestations of systemic lupus erythematosus: a single-centre case series Gaia Ferracane1|2, Jessika Dichiara1|2, Elena Manna1|2, Lorenzo Mattia Bianchessi1|2, Giovanni Zanframundo1|2, Serena Bugatti1|2, Veronica Codullo1|2, Lorenzo Cavagna1|2, Francesca Bottazzi1|2 | 1Department of Internal Medicine and Therapeutics, Università di Pavia; 2Division of Rheumatology, IRCCS Policlinico San Matteo, Pavia, Italy
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PO:07:103 | Tocilizumab use in patients with rheumatoid arthritis and malignancy: a monocentric experience Vittorio Dibenedetto1|2|3, Nicola Farina1|2, Nicola Boffini1|2, Alessandro Tomelleri1|2, Adriana Cariddi1|2, Elena Baldissera1|2, Marco Matucci-Cerinic1|2|3, Lorenzo Dagna1|2|3. | 1Unit of Immunology, Rheumatology, Allergy and Rare Diseases, IRCCS San Raffaele Hospital, Milano, Italy; 2Inflammation, Fibrosis and Ageing Intitiative INFLAGE, IRCCS San Raffaele Hospital, Milano, Italy; 3Vita-Salute San Raffaele University, Milano, Italy.
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PO:20:006 | Efficacy of denosumab in glucocorticoid-induced osteoporosis patients with prior exposure to intravenous aminobisphosphonates Kiren Khalid1, Alessandro Giollo1, Mariangela Salvato1, Francesca Frizzera1, Lorenzo Di Luozzo1, Bernd Raffeiner2, Andrea Doria1 | 1Rheumatology Unit, Department of Medicine - DIMED, University of Padova, Padova, Italy; 2Department of Rheumatology, Bolzano Central Hospital, Bolzano, Italy
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PO:02:025 | Real-World Comparative Effectiveness of Upadacitinib in Psoriatic Arthritis: Evaluation of Switching to Upadacitinib Versus Tumor Necrosis Factor Inhibitors or Interleukin-17 Inhibitors After First-Line Tumor Necrosis Factor Inhibitors Valentina Carlini1, Philip Mease2, William Tillett3, Xiaolan Ye4, Christopher Saffore4, Molly Edwards5, Isabel Truman5, Sophie Barlow5, Jayne Stigler4, Bhumik Parikh4, Daniel Aletaha6 | 1Abbvie srl Roma, Italy; 2University of Washington School of Medicine Seattle, United States Minor Outlying Islands; 3Department of Rheumatology, Royal National Hospital for Rheumatic Diseases Bath, United Kingdom; 4Abbvie Inc. North Chicago, United States Minor Outlying Islands; 5Adelphi Real World Bollington, United Kingdom; 6Division of Rheumatology, Department of Medicine, Medical University of Vienna, Vienna, Austria
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PO:16:233 | Efficacy of voclosporin on nephritis in patients with variable gain of function of TLR7 affected by lupus: clinical case Veronica Spedicato1, Laura Coladonato1, Marco Fornaro1, Marlea Lavista1, Daniele Sabella1, Marco Capodiferro1, Maria Morrone1, Crescenzio Scioscia1, Giuseppe Lopalco1, Florenzo Iannone1 | 1Unit of Rheumathology, Department of Precision and Regenerative Medicina, Area JonicaJ, University of Bari, Italy
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PO:06:079 | Weighing the burden: how body mass index shapes clinical outcomes in rheumatoid arthritis. Insights from a large Italian cohort Marco Capodiferro1, Marco Fornaro1, Gian Luca Erre2, Matteo Piga3, Elena Bartoloni Bocci4, Andreina Manfredi5, Ennio Giulio Favalli6, Maria Sole Chimenti7, Serena Guiducci8, Eleonora Celletti9, Addolorata Corrado10, Alessandro Giollo11, Simone Parisi12, Ivan Giovannini13, Elisa Gremese14, Garifallia Sakellariou15, Ombretta Viapiana16, Fabiola Atzeni17, Francesca Romana Spinelli18, Fabio Cacciapaglia1|19. | 1Rheumatology Unit, Department of Precision and Regenerative Medicine and Ionian Area DiMePRe-J University of Bari, Bari, Italy; 2Dipartimento di Scienze Mediche, Chirurgiche e Sperimentali, Università degli Studi di Sassari, Sassari, Italy; 3Rheumatology Unit, AOU Cagliari, Department of Medical Sciences and Public Health, University of Cagliari, Cagliari, Italy; 4Rheumatology Unit, Department of Medicine and Surgery, University of Perugia, Perugia, Italy; 5Rheumatology Unit, Azienda Ospedaliera Universitaria Policlinico of Modena, Modena, Italy; 6Dpt of Rheumatology, G. Pini Institute, Milano, Italy; 7Rheumatology, Allergology and Clinical Immunology, Department of Systems Medicine, University of Rome Tor Vergata, Rome, Italy; 8Department of Experimental and Clinical Medicine, Division of Rheumatology, University of Florence, Firenze, Italy; 9Rheumatology Unit, SS Annunziata Hospital, Chieti, Italy; 10Rheumatology Unit, Department of Medical and Surgical Sciences, University of Foggia, Foggia, Italy; 11Rheumatology Unit, Department of Medicine, University of Padova Hospital Trust, Padova, Italy; 12Rheumatology Department, A.O.U. Città della Salute e della Scienza, Torino, Italy; 13Rheumatology Department, Santa Maria della Misericordia Hospital, Udine, Italy; 14Rheumatology and Clinical Immunology, IRCCS Humanitas Research Hospital, Rozzano (MI), Italy; 15Department of Internal Medicine and Therapeutics, University of Pavia, Istituti Clinici Scientifici Maugeri, Pavia, Italy; 16Rheumatology Unit, Department of Medicine, University and Azienda Ospedaliera Universitaria Integrata of Verona, Verona, Italy; 17Rheumatology Unit, Department of Experimental and Internal Medicine, University of Messina, Messina, Italy; 18Reumatology Unit, Department of Internal, Anesthesiological, and Cardiovascular Clinical Sciences, Sapienza University, Roma, Italy; 19Miulli General Hospital Acquaviva - Department of Medicine and Surgery, LUM F. De Gennaro University, Casamassima (BA), Acquaviva delle Fonti (BA), Italy.
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PO:19:286 | Genetic testing reveals an unexpected case of mevalonate kinase deficiency in a 37-year-old patient with AA renal amyloidosis and good response to colchicine Francesca Crisafulli1, Paolo Airò2, Federica Mescia3, Gianmarco Lugli3, Gianfranco Savoldi4, Claudia Izzi3|5, Federico Alberici3, Marco Cattalini6, Franco Franceschini1, Micol Frassi2. | 1Rheumatology and Clinical Immunology Unit, ASST Spedali Civili and University of Brescia, Brescia, Italy; 2Rheumatology and Clinical Immunology Unit, ASST Spedali Civili of Brescia, Brescia, Italy; 3U.O Nefrologia, ASST Spedali Civili di Brescia e Università degli Studi di Brescia, Brescia, Italy; 4Medical genetics Laboratory, Laboratory Department ASST Spedali Civili di Brescia, Brescia, Italy; 5Struttura Complessa di Genetica Clinica, ASST Spedali Civili di Brescia, Brescia, Italy; 6Pediatrics Clinic, University of Brescia and ASST Spedali Civili of Brescia, Brescia, Italy.
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CO:09:6 | Risk of disease flare during pregnancy and postpartum in inflammatory arthritis: association with therapy discontinuation in the prospective P-RHEUM.it study Dina Zucchi1, Chiara Tani1, Francesca Crisafulli2, Alessia Gatti2, Maria Gerosa3, Cecilia Chighizola3, Melissa Padovan4, Salvatore D'Angelo5, Florenzo Iannone6, Maria Sole Chimenti7, Claudia Lomater8, Francesca Serale9, Veronique Ramoni10, Oscar Epis11, Bernd Raffeiner12, Ariela Hoxha13, Andrea Doria14, Leonardo Santo15, Valentina Canti16, Francesca Bellisai17, Giovanna Cuomo18, on behalf of the P-Rheumit Investigators19, Greta Carrara20, Cristina Di Nicola20, Davide Rozza20, Carlo Alberto Scirè20, Maria Chiara Gerardi11, Angela Tincani2, Laura Andreoli2, Marta Mosca1. | 1Rheumatology Unit, University of Pisa and Azienda Ospedaliero Universitaria Pisana; 2Rheumatology and Clinical Immunology Unit, ASST Spedali Civili, Brescia; 3Clinical Rheumatology Division, ASST Gaetano Pini-CTO and University of Milano; 4Rheumatology Unit, Azienda Ospedaliero-Universitaria S. Anna and University of Ferrara; 5Rheumatology Department of Lucania - San Carlo Hospital, Potenza; 6Rheumatology Unit, DiMePRE-J, University of Bari; 7Department of Systems Medicine, Rheumatology, Allergology and Clinical Immunology, University of Rome-Tor Vergata, Roma; 8Torino Academic Rheumatology Center, A.O. Mauriziano di Torino, University of Torino; 9Rheumatology Unit, ASL CN1 Cuneo; 10Internal Medicine Department, ASST Lodi - Ospedale Maggiore di Lodi; 11Division of Rheumatology, Multispecialist Medical Department, Grande Ospedale Metropolitano Niguarda, Milano; 12Department of Rheumatology, Central Hospital of Bolzano SABES-ASDAA, Bolzano; 13General Medicine and Thrombosis and Hemorrhagic Unit, Department of Medicine, University of Padova; 14Rheumatology Unit, Department of Medicine, University of Padova; 15Rheumatology Unit, Mons. Dimiccoli Hospital, Barletta; 16Division of Immunology, Transplantation and Infectious Diseases, IRCCS Ospedale San Raffaele, Milano; 17Rheumatology Unit, Department of Medicine, Surgery and Neurosciences, University of Siena; 18Precision Medicine Department, University of Campania L. Vanvitelli, Napoli; 19The Italian Society for Rheumatology; 20Epidemiology Research Unit of the Italian Society for Rheumatology, Milano, Italy
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PO:16:234 | Differential efficacy of induction treatments for lupus nephritis at onset and relapses: an observational study Giuseppe Alvise Ramirez1|2, Gabriele D Gallina1, Chiara Calabrese1|2, Serena Nannipieri1|2, Marta Calatroni3|4, Francesco Reggiani3|4, Giovanni Benanti1, Enrica Paola Bozzolo1, Raffaele Ceniccola2, Luca Moroni1|2, Marco Matucci-Cerinic1|2, Gabriella Moroni3|4, Lorenzo Dagna1|2 | 1IRCCS San Raffaele Hospital, Unit of Immunology, Rheumatology, Allergy and Rare Diseases Milan, Italy; 2Vita- Salute San Raffaele University Milan, Italy; 3IRCCS Humanitas Research Hospital, Nephrology and Dialysis Division Rozzano, Milan, Italy; 4Humanitas University, Department of Biomedical Sciences Rozzano, Milan, Italy
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PO:04:050 | Cluster-Based Endotyping of Psoriatic Arthritis in a Monocentric Italian Cohort: A Real-World study Eneida Cela1, Arianna D'Antonio1, Luigi Fiannacca1, Alberto Bergamini1, Maxime Breban2, Felicie Costantino2, Maria Sole Chimenti1 | 1Rheumatology, Allergology and Clinical Immunology, Department of System Medicine, University of Rome Tor Vergata Rome, Italy; 2Rheumatology Department, AP-HP, Ambroise-Paré Hospital Paris, France
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PO:06:083 | Clinical characteristics and outcomes of late- and young-onset rheumatoid arthritis in relation to autoantibody status Federica Sabatelli1|2, Ludovico De Stefano1|2, Clelia Zampaglione1|2, Lisa Bergianti1|2, Blerina Xoxi1|2, Antonio Manzo1|2, Carlomaurizio Montecucco1|2, Serena Bugatti1|2. | 1Department of Internal Medicine and Therapeutics, University of Pavia, Pavia; 2Division of Rheumatology, IRCCS Policlinico San Matteo Foundation, Pavia, Italy.
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PO:15:212 | Anifrolumab induces a rapid improvement in joint inflammation in Systemic Lupus Erythematosus patients: an ultrasonographic study Valeria Moretti, Fulvia Ceccarelli, Claudia Ciancarella, Valerio Fiorilli, Francesca Romana Spinelli, Fabrizio Conti | Sapienza Università di Roma, Italy
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PO:16:227 | Anifrolumab for Systemic Lupus Erythematosus: Preliminary Safety and Efficacy Findings from the Italian Experience Paola Bizioli1|2, Chiara Orlandi1|2, Claudia Barison1|2, Cesare Tomasi3, Alessia Caproli1, Silvia Piantoni1|2, Simona Signorini4, Emirena Garrafa4, Cecilia Nalli1, Micol Frassi1, Ilaria Cavazzana1|2, Micaela Fredi1|2, Franco Franceschini1|2 | 1Rheumatology and Clinical Immunology Unit - ERN ReCONNET, ASST Spedali Civili of Brescia, Italy; 2Department of Clinical and Experimental Sciences, University of Brescia, Italy; 3Department of Clinical and Experimental Sciences, University of Brescia, Italy; 4Laboratory of Clinical Chemistry, Department of Molecular and Translational Medicine, University of Brescia, Italy
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