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PO:01:007 | Modulation of cellular senescence in psoriatic arthritis: exploring the potential impact of b/tsDMARDs treatment on telomere length, mtDNA copy number, and oxidative damage Eneida Cela1, Giada De Benedittis2, Arianna D'Antonio1, Andrea Latini3, Chiara Morgante2, Cinzia Cicacci3, Paola Conigliaro1, Mauro Fatica1, Giulia Mori1, Giuseppe Novelli2, Paola Borgiani2, Maria Sole Chimenti1. | 1Rheumatology, Allergology and Clinical Immunology, Department of System Medicine, University of Rome Tor Vergata, Rome, Italy; 2Department of Biomedicine and Prevention, Section of Genetics, University of Rome Tor Vergata, Rome, Italy; 3UniCamillus Saint Camillus International University of Health Sciences, Rome, Italy.
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PO:37:266 | Long-term manifestation of graft-versus-host disease presenting as a vasculitic-like syndrome: a rare case report Camilla Mazzanti1, Gianluca Santoboni1, Claudio Angrisani1, Massimiliano De Simone1, Giuliana Marciani1, Alessandra Fiorentini1 | 1Ospedale Santa Rosa Viterbo, Italy
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PO:02:027 | Fast food, slow damage: ultra-processed foods, Western diet and inflammatory arthritis. A systematic scoping review Gianluca Poncina1, Federica Gardin2, Giacomo Cozzi1, Laura Scagnellato1, Mariagrazia Lorenzin1, Stefano Rizzetto1, Caterina Robusto1, Francesca Oliviero1, Valérie Tikhonoff2, Roberta Ramonda1. | 1Rheumatology Unit, Department of Medicine-DIMED, University - Padova University Hospital, Padova, Italy; 2Department of Medicine-DIMED, University - Padova University Hospital, Padova, Italy.
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PO:31:167 | Increased M2 pro-fibrotic marker expression in circulating monocytes and cultured monocyte-derived macrophages in systemic sclerosis patients with progressive interstitial lung disease Vanessa Smith1|2, Stefano Soldano3, Rosanna Campitiello3|5, Emanuele Gotelli3|4, Paola Montagna3, Elvis Hysa3|5, Tamara Vojinovic3|4, Carmen Pizzorni3|4, Sabrina Paolino3|4, Alberto Sulli3|4, Maurizio Cutolo3|4. | 1Department of Internal Medicine and Department of Rheumatology, Ghent University Hospital, Ghent, Belgium; 2Unit for Molecular Immunology and Inflammation, VIB Inflammation Research Centre, Ghent, Belgium; 3Laboratory of Experimental Rheumatology and Academic Division of Clinical Rheumatology, Department of Internal Medicine, Genova, Italy; 4IRCCS Ospedale Policlinico San Martino, Genova, Italy; 5Department of Experimental Medicine DIMES, University of Genova, Genova, Italy.
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PO:11:172 | Not all vasculitis look the same: a difficult diagnosis Marta Arese1|2, Miriam Perino1|2, Sofia Aliprandi1|2, Antonella Murgo2, Maria Gerosa1|2, Roberto Felice Caporali1|2 | 1UOC Reumatologia AOR San Carlo, Potenza; 2Reumatologia Clinica, ASST Gaetano Pini-CTO, Milano, Italy
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S02:6 | Monocyte-Driven Inflammation and Inflammasome Activation in ANCA-Positive EGPA: Evidence of Persistent Immune Activation During Remission Chiara Baggio1, Luca Iorio1, Carlotta Boscaro2|3, Federica Davanzo1, Marta Tonello1, Mattia Albiero4, Andrea Doria1, Paolo Sfriso1, Roberto Padoan1, Francesca Oliviero1 | 1Rheumatology Unit, Department of Medicine, University of Padova, Italy; 2Department of Medicine, University of Padova, Italy; 3Veneto Institute of Molecular Medicine, Laboratory of Experimental Diabetology, Italy; 4Department of Surgery, Oncology, and Gastroenterology, University of Padova, Italy
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PO:03:035 | Biomarkers of Gut Epithelial Damage, Microbial Translocation, and Innate Immune Activation Characterize Patients with Axial Psoriatic Arthritis from Psoriasis Patients: Soluble Biomarker Analysis Insights from the ATTRACT Study Giulia Marchionni1, Valentino Paci1, Silvia Svegliati1, Raffaella Sordillo1, Federico Fiorini1, Melania Giannoni1, Anna Campanati1, Raissa Di Zio1, Devis Benfaremo1, Giuseppe Lopalco2, Florenzo Iannone2, Ennio Lubrano3, Alberto Cauli4, Gianluca Moroncini1, Dennis Poddubnyy5, Fabian Proft6, Michele M Luchetti Gentiloni1 | 1Marche Polytechnic University and Azienda Ospedaliero-Universitaria delle Marche, Ancona, Italy; 2University of Bari, Bari, Italy; 3Molise University, Campobasso, Italy; 4University of Cagliari, Azienda Ospedaliero Universitaria di Cagliari, Monserrato, Italy; 5University of Toronto, Toronto, Canada; 6Charité-Universitätsmedizin, Berlino, Germany
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PO:28:128 | Rheumatic fever: an atypical case Giovanni Italiano1, Melania Coscia1, Arianna Monteforte1 | 1AORN S. Anna e S. Sebastiano Caserta, Italy
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S07:5 | Ankle ultrasound patterns may in the identification of Löfgren’s syndrome in patients with acute-onset erythema nodosum Davide Corradini1, Alberto Floris1, Andrea Carta2, Mattia Congia1, Elisabetta Chessa1, Matteo Piga1, Alberto Cauli1. | 1Rheumatology Unit, AOU and University of Cagliari, Cagliari, Italy; 2Department Economics and Business, University of Cagliari, Cagliari, Italy.
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PO:33:192 | Hand Microvascular Damage Is Associated with Hand Bone Loss in Systemic Sclerosis Rosanna Campitiello1|3, Sabrina Paolino1|2, Andrea Casabella1|2, Giulia Davoli1|2, Elisa Caratto1|2, Emanuele Gotelli1|2, Elvis Hysa1|2, Carmen Pizzorni1|2, Vanessa Smith4|5, Alberto Sulli1|2, Maurizio Cutolo1|2 | 11. Laboratory of Experimental Rheumatology and Academic Division of Clinical Rheumatology, Department of Internal Medic Genova, Italy; 2IRCCS Ospedale Policlinico San Martino Genova, Italy; 3Department of Experimental Medicine DIMES, University of Genova Genova, Italy; 4Department of Internal Medicine and Department of Rheumatology, Ghent University Hospital Ghent, Belgium; 5Unit for Molecular Immunology and Inflammation, VIB Inflammation Research Centre, Ghent, Belgium
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PO:07:097 | CGRP and CALCRL localization supports the role of fibroblast-like synoviocytes in rheumatoid arthritis pain pathways Giada La Spina1, Cristina Garufi2, Mattia Caliste2, Martina Leopizzi3, Valeria Di Maio3, Cristiano Alessandri2, Fabrizio Conti2, Francesca Romana Spinelli2 | 1Sapienza University of Rome, Dipartimento di Medicina Molecolare, Roma, Italy; 2Sapienza University of Rome, Dipartimento di Scienze Cliniche Internistiche, Anestesiologiche e Cardiovascolari, Roma, Italy; 3Sapienza University of Rome, Dipartimento di Scienze e Biotecnologie Medico-Chirurgiche, Roma, Italy
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PO:37:263 | First non invasive visualization of vasculitis in the retinal arteries by high resolution optical coherence tomography in a patient with giant cell arteritis Ruggiero Mascolo1, Chiara Facoetti1, Claudia Nardi2, Stefano Erba2, Martina Martelli1, Gabriella Marinaro1, Giulia Dieguez1, Giacomo Iacomelli1, Chiara Carollo1, Michel Chevallard3, Bruno Lucchino3, Mariaeva Romano3, Andrea Locatelli3, Donatella Ventura3, Giovanna Randisi3, Giuliana La Paglia3, Alessandra Mutti3, Alessandro Invernizzi2, Stefano De Angelis2, Giovanni Staurenghi2, Antonio Brucato4, Enrico Tombetti4. | 1Dipartimento di Medicina Interna, ASST Fatebenefratelli-Sacco, Università degli studi di Milano, Milano, Italy; 2U.O. Oftalmologia, ASST Fatebenefratelli-Sacco, Università degli studi di Milano, Milano, Italy; 3U.O. Reumatologia, ASST Fatebenefratelli-Sacco, Università degli studi di Milano, Milano, Italy; 4Dipartimento di scienze cliniche e biomediche, ASST Fatebenefratelli-Sacco, Università degli studi di Milano, Milano, Italy.
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PO:22:039 | A rare form of interstitial lung disease: granulomatous and lymphocytic interstitial lung disease Francesca Cozzini1|2, Francesco Falco1, Alberto Cavazza1, Lucia Spaggiari3, Chiara Marvisi1, Francesca Petrillo1|2, Caterina Ricordi1|2, Francesco Muratore1|2, Fabio Brandolino1, Ilaria Chiapparoli1, Carlo Salvarani1|2, Andreina Manfredi1|2 | 1IRCCS Policlinico San Matteo, UO di Reumatologia, Pavia; 2Università degli studi di Modena e Reggio Emilia, Modena, Italy
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PO:10:150 | A case of pulmonary hypertension in Whipple's disease Alba Chiara Pozzi1|2, Giulia Fontana1|2, Francesca Crisafulli1|2, Guarino Daniele3, Monica Salvi3, Massimiliano Palazzini3, Francesco Biagi4|5, Ilaria Cavazzana1|2, Franco Franceschini1|2, Micol Frassi1. | 1Rheumatology and Clinical Immunology Unit ERN-ReCONNECT, ASST Spedali Civili, Brescia, Italy; 2Department of Clinical Experimental Sciences, University of Brescia, Brescia; 3IRCCS Azienda Ospedaliero-Universitaria di Bologna, University of Bologna, Cardiology Unit, DIMEC, Bologna; 4University of Pavia, Department of Internal Medicine and Therapeutics, Pavia; 5Istituti Clinici Scientifici Maugeri IRCCS, Gastroenterology Unit of Pavia Institute, Pavia, Italy.
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PO:24:057 | Qualitative and quantitative analysis of nailfold videocapillaroscopy in patients with idiopathic inflammatory myopathies: focus on muscle histology Jacopo Landro1, Marius Cadar1, Davide Mohammad Reza Beigi1|2, Ilaria Bisconti1, Francesca Romana Di Ciommo1, Elena Platania1, Martina Salerno1, Beatrice De Girolamo1, Annalisa Villa1, Angelica Gattamelata1, Simona Truglia1, Cristiano Alessandri1, Fabrizio Conti1, Valeria Riccieri1. | 1Policlinico Umberto I, Roma, Italy; 2Clinica Reumatologica Madonna dello Scoglio, Cotronei, Italy.
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PO:37:258 | Neutrophil and eosinophil extracellular traps in eosinophilic granulomatosis with polyangiitis: phenotype-based characterization and response to mepolizumab Michele Moretti1, Francesco Ferro2, Francesco Pisani1, Elisa Ferrigno1, Gaetano La Rocca1, Federica Di Cianni3, Rosaria Talarico2, Marta Mosca1, Chiara Baldini1, Ilaria Puxeddu1. | 1University of Pisa - Department of Clinical and Experimental Medicine, Pisa, Italy; 2Azienda Ospedaliero Universitaria Pisana - Rheumatology Unit, Pisa, Italy; 3University of Siena, Siena, Italy.
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PO:11:165 | Clinical mimicry and therapeutic challenge: A Case of Rapidly Progressive Mixed Connective Tissue Disease Elena Maria Di Virgilio1, Elisabetta Chessa2, Valentina Ibba2, Cosimina Matulli2, Jessica Sorgia1, Andrea Pace1, Matteo Piga1|2, Alberto Cauli1|2 | 1Università degli studi di Cagliari-Reumatologia, Cagliari, Italy; 2Struttura complessa di Reumatologia- AOU Cagliari, Cagliari, Italy
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CO:06:3 | Clinical and laboratory markers for distinguishing VEXAS from Schnitzler's syndrome in male patients with skin involvement: insights from the International AIDA Network Registries Valeria Caggiano1, Jessica Sbalchiero1, Micol Frassi2, Andrea Hinojosa-Azaola3, Francesca Crisafulli2, Franco Franceschini2, Paolo Sfriso4, Sara Bindoli4, José Hernández-Rodríguez5, Henrique A. Mayrink Giardini6, Giuseppe Lopalco7, Florenzo Iannone7, Ombretta Viapiana8, Amato De Paulis9, Lorenzo Dagna10, Antonio Gidaro11, Serena Bugatti12, Matteo Piga13, Fabrizio Conti14, Rosetta Vitetta15, Cecilia Chighizola16, Marcello Govoni17, Giacomo Emmi18, Paola Triggianese19, Carmelo Gurnari19, Bruno Frediani1, Claudia Fabiani1, Luca Cantarini1, Antonio Vitale1, for the AIDA Network1 | 1Department of Medical Sciences, Surgery and Neurosciences, University of Siena; 2University of Brescia, Italy; 3Department of Immunology and Rheumatology, Mexico City, Mexico; 4Rheumatology Unit, University of Padova, Italy; 5Clinical Unit of Autoinflammatory Diseases, Hospital Clínic of Barcelona, Spain; 6Rheumatology Division, Universidade de São Paulo, Brazil; 7University of Bari; 8Rheumatology Unit, University and Azienda Ospedaliera Universitaria Integrata of Verona; 9University of Napoli "Federico II"; 10Università Vita-Salute San Raffaele, Milano; 11Luigi Sacco Hospital, University of Milano; 12Università di Pavia; 13University and AOU of Cagliari; 14AOU Policlinico Umberto I, Sapienza University of Rome; 15Unit of Rheumatology, ASL Sant' Andrea Hospital, Vercelli; 16University of Milano; 17Azienda Ospedaliero-Universitaria S. Anna, Ferrara; 18University of Trieste; 19University of Rome-Tor Vergata, Rome, Italy.
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PO:06:082 | Correlation between ultrasonographic parameters and the Krenn synovitis score in patients with chronic infiammatory arthropathy undergoing ultrasound-guided synovial biopsy: a prospective cohort study Maria Capita1, Carlo Garaffoni1, Marianna Tamussin1, Serena Ceccato1, Giovanni Lanza2, Alessandra Bortoluzzi1, Marcello Govoni1, Ettore Silvagni1 | 1Unità di Reumatologia, Azienda Ospedaliero - Universitaria S. Anna, Cona (FE); 2Anatomia Patologica, Dipartimento di Medicina Traslazionale Università di Ferrara, Cona (FE), Italy
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PO:36:250 | Eosinophilic granulomatosis with polyangiitis associated to Alpha-1 Antitrypsin Deficiency: a land still unexplored Maria Grazia Malandra1, Vacchi Caterina1, Santoro Filippo1, Cassone Giulia1, Martina Orlandi1, Stefania Cerri1, Dilia Giuggioli1 | 1Università di Modena - Reggio Emilia, S.C. Reumatologia Azienda Ospedaliera Universitaria Policlinico di Modena Modena, Italy; 2S.C. Reumatologia Azienda Ospedaliera Universitaria Policlinico di Modena Modena, Italy; 3Università di Modena e Reggio Emilia, S.C. Reumatologia Azienda Ospedaliera Universitaria Policlinico di Modena Modena, Italy; 4S.C. Reumatologia Azienda Ospedaliera Universitaria Policlinico di Modena Modena, Italy; 5Università di Modena e Reggio Emilia, S.C. Reumatologia Azienda Ospedaliera Universitaria Policlinico di Modena Modena, Italy; 6Università di Modena e Reggio Emilia, S.C. Reumatologia Azienda Ospedaliera Universitaria Policlinico di Modena Modena, Italy; 7Università di Modena e Reggio Emilia, S.C. Reumatologia Azienda Ospedaliera Universitaria Policlinico di Modena Modena, Italy
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PO:31:172 | Age and timing of onset of Raynaud's phenomenon and first non-Raynaud sign/symptom as prognostic factors in systemic sclerosis: a retrospective analysis from the systemic sclerosis progression investigation registry of the Italian Society for Rheumatology Silvia Peretti1, Cosimo Bruni2, Silvia Laura Bosello3, Fabio Cacciapaglia4-5, Corrado Campochiaro6-7, Veronica Codullo8, Lorenzo Dagna6-7, Rossella De Angelis9, Giacomo De Luca6-7, Dilia Giuggioli10, Serena Guiducci1, Florenzo Iannone4, Francesca Ingegnoli11, Valeria Riccieri12, Marco Matucci Cerinic6-7, Clodoveo Ferri10-13, Silvia Bellando Randone1. | 1Division of Rheumatology, Scleroderma Unit, Department of Experimental and Clinical Medicine, University of Florence, AO, Firenze, Italy; 2Division of Rheumatology, University Hospital Zurich, University of Zurich, Zurich, Switzerland; 3Rheumatology Division, Catholic University of the Sacred Heart, Fondazione Policlinico Universitario A. Gemelli- IRCCS, Roma, Italy; 4Rheumatology Unit, Department of Precision and Regenerative Medicine-Ionian Area, University of Bari Aldo Moro, Bari, Italy; 5Reumatology Service, Internal Medicine Unit F.Miulli General Hospital, Acquaviva delle Fonti -Department of Medicine a, Bari, Italy; 6Unit of Immunology, Rheumatology, Allergy and Rare Diseases UnIRAR, Inflammation, Fibrosis and Ageing initiative INFL, Milano, Italy; 7Vita-Salute San Raffaele University, Milano, Italy; 8Department of Internal Medicine and Therapeutics, Università di Pavia, Italy; Division of Rheumatology, Fondazione IRCCS, Pavia, Italy; 9Rheumatology Unit, Department of Clinical and Molecular Sciences, Polytechnic University of Marche, Ancona, Italy; 10Rheumatology Unit, School of Medicine, University of Modena and Reggio Emilia, Modena, Italy; 11Division of Clinical Rheumatology, ASST Pini, Dept. of Clinical Sciences and Community Health, Research Center for Adul, Milano, Italy; 12Department of Rheumatology, Sapienza University of Rome, Roma, Italy; 13Rheumatology Clinic Madonna dello Scoglio Crotonei, Crotone, Italy.
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PO:01:001 | Clinical and histopathological features of refractory psoriatic arthritis undergoing ultrasound-guided synovial biopsy: comparison between non-inflammatory and persistent inflammatory profiles Marianna Tamussin1, Carlo Garaffoni1, Maria Capita1, Serena Ceccato1, Giovanni Lanza2, Mariangela Salvato3, Kiren Khalid3, Francesca Frizzera3, Lorenzo Di Luozzo3, Annalisa Angelini4, Roberta Ramonda3, Alessandra Bortoluzzi1, Andrea Doria3, Marcello Govoni1, Alessadro Giollo3, Ettore Silvagni1 | 1Rheumatology Unit, Department of Medical Sciences, University of Ferrara and Azienda Ospedaliero-Universitaria S. Anna Ferrara, Italy; 2Pathology Unit, Department of Translational Medicine, University of Ferrara, Ferrara Ferrara, Italy; 3Rheumatology Unit, Department of Medicine , DIMED, University of Padua Padova, Italy; 4Cardiovascular Pathology, Department of Cardiac, Thoracic, Vascular Sciences and Pulic Health, University of Padua, Padova, Italy
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