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PO:22:033 | Unraveling VEXAS syndrome: when skin manifestations and monoclonal gammopathy precede hematological myeloid alterations Laura Di Centa1, Simone Longhino1, Valeria Manfrè1, Stefania Sacco1, Luca Quartuccio1 | 1ASST Papa Giovanni XXIII, Bergamo, Italy
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PO:11:165 | Clinical mimicry and therapeutic challenge: A Case of Rapidly Progressive Mixed Connective Tissue Disease Elena Maria Di Virgilio1, Elisabetta Chessa2, Valentina Ibba2, Cosimina Matulli2, Jessica Sorgia1, Andrea Pace1, Matteo Piga1|2, Alberto Cauli1|2 | 1Università degli studi di Cagliari-Reumatologia, Cagliari, Italy; 2Struttura complessa di Reumatologia- AOU Cagliari, Cagliari, Italy
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PO:11:171 | Subcutaneous tocilizumab use in a young-onset mixed connective tissue disease patient with multiple treatment failures Rhaysa Araujo Mousinho1, Elide Lupi2, Massimiliano Limonta2 | 1Clinica di Reumatologia, Dipartimento di Medicina and 2Istituto di Anatomia Patologica, Dipartimento di Medicina di Laboratorio, Osp. S. M. della Misericordia, Università di Udine, Italy
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PO:07:108 | Achievement of Treatment Targets and Maintenance of Response with Upadacitinib in Patients with Moderate-to-Severe Rheumatoid Arthritis in a Real-world Setting: Final 2-year Outcomes from the UPHOLD Study Enrico Marchetta1, Andrew Östör2|8, Eugen Feist3, Prodromos Sidiropoulos4, Jérôme Avouac5, Martin Rebella6|7, Rajaie Namas9, Erin Mcdearmon Blondell10, Ivan Lagunes10, Tianming Gao10, Tim Shaw10, Suzan Attar11 | 1AbbVie Srl Roma, Italy; 2Monash University and Emeritus Research, Melbourne, Victoria, Melbourne, Australia; 3Helios Department of Rheumatology and Clinical Immunology, Vogelsang-Gommern, Vogelsang Gommern, Germany; 4Faculty of Medicine, University of Crete, Heraklion, Heraklion, Greece; 5Service de Rhumatologie, Hôpital Cochin, AP HP Centre Université Paris Cité, Parigi, France; 6Departamento de Medicina, Facultad de Medicina, Universidad de la República, Montevideo, Montevideo, Uruguay; 7Unidad de Enfermedades Autoinmunes Sistémicas, MUCAM, Montevideo, Montevideo, Uruguay; 8Australian National University, Camberra, Australia; 9Medical Subspecialties Institute, Division of Rheumatology, Cleveland Clinic Abu Dhabi, United Arab Emirates; 10AbbVie Inc., North Chicago, Illinois, United States of America Chicago, USA; 11King Abdulaziz University, Jeddah, Saudi Arabia
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PO:38:278 | Cognitive behavioural therapy vs. physical therapy for chronic primary low back pain: a systematic review with meta-analysis of randomised controlled trials Luca Castioni1, Stefano Salvioli2 | 1Università degli studi di Ferrara; 2Scuola di fisioterapia Claudiana, Bolzano, Italy
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PO:11:175 | Dermatomyositis and immunosuppressant treatment: a case of Staphylococcus aureus pneumonia in a hospitalized patient Simona Fichera1, Andrea Cito1, Martina Vigilia1, Maria Morrone1, Teresa Caferri1, Crescenzio Scioscia1, Simone Perniola1, Giuseppe Lopalco1, Florenzo Iannone1. | 1Unit of Rheumatology, Department of Precision and Regenerative Medicine, Area Jonica, University of Bari, Bari, Italy.
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PO:37:269 | Intensive therapeutic plasma exchange in life-threatening ANCA-associated vasculitis Davide Bertelle, Riccardo Bixio, Francesco Pollastri, Maurizio Rossini, Angelo Fassio, Alessandro Giollo | Unità di Reumatologia, Dipartimento di Medicina Clinica e Sperimentale, Università di Pisa
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PO:24:068 | Case Report: ‘Spontaneous Pneumomediastinum in a Patient with MDA5-Positive Dermatomyositis and Severe Pulmonary Fibrosis’ Carlotta Braga1, Margherita Rizzo1, Marta Raschellà1, Beatrice Maranini1, Gioacchino Schifino2, Aldo Carnevale3, Marcello Govoni1, Andrea Lo Monaco1 | 1Rheumatology Unit, Department of Medical Sciences, University of Ferrara and Azienda Ospedaliero-Universitaria S. Anna Ferrara, Italy; 2Respiratory Medicine Unit, Department of Cardio-Thoracic-Vascular Pathologies, Arcispedale Sant'Anna, Ferrara, Italy; 3Radiology Unit, Department of Translational Medicine, University of Ferrara, Italy
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PO:31:163 | Safety and tolerability of home-based prostacyclin analogue therapy in vascular manifestations of the scleroderma spectrum: results of a monocentric study Alice Dionisi1, Lucrezia Verardi2, Annacarla Finucci2, Paola Volpe2, Anna Cinzia Raspa2, Paola Cipriani1, Raffaele Zicolella2 | 1Reumatologia,Dipartimento di Sscienze Cliniche Applicate e Biotecnologiche, Università degli Studi dell'Aquila; 2UOC Reumatologia, Ospedale Civile di Pescara, Italy
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S02:5 | Combined anti-IL-5/IL-5r and dupilumab therapy in eosinophilic granulomatosis with polyangiitis: a European retrospective study Miriam Guerini1, Pavel Novikov2, Roberto Padoan3, Georgina Espigol Frigolé4, Jan Willem Cohen Tervaert5, Vincent Grobost6, Laurent Guilleminault7, Jan Walter Schroeder8, Bernhard Hellmich9, Joana Martins Martinho10, Camillo Ribi11, Matthieu Groh12, Benjamin Terrier13. | 1IRCCS Policlinico S. Matteo, University of Pavia, Pavia, Italy; 2Sechenov University, Moscow, Russia; 3University of Padova, Padova, Italy; 4Hospital Clinic, University of Barcelona, Barcelona, Spain; 5University of Alberta, Edmonton, Canada; 6CHU Estaing Clermont-Ferrand France; 7Toulouse University Toulouse France; 8ASST Grande Ospedale Metropolitano Niguarda, Milano, Italy; 9Medius Kliniken Kirchheim-Teck Germany; 10ULS Santa Maria, Lisbon, Portugal; 11Centre Hospitalier Universitaire Vaudois, Lausanne, Switzerland; 12Hopital Foch, Suresnes, France; 13Service de Medecine interne, Hopital Cochin, AP-HP, Paris, France.
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PO:17:255 | Efficacy and safety of voclosporin in the management of lupus nephritis: a case series Alessandra Oliva1, Elisabetta Chessa2, Marta Paola Pireddu1, Marianna Salis1, Giulia Rizzo1, Fabio Congiu1, Elena Ragusa1, Antonello Pani3|4, Alberto Cauli1|2, Nicola Lepori3|4, Matteo Piga1|2 | 1UOC Reumatologia, Dipartimento di Scienze Mediche e Salute Pubblica, Università degli Studi di Cagliari; 2UOC Reumatologia, AOU Cagliari; 3SC Nefrologia e Dialisi, Università degli Studi di Cagliari; 4SC Nefrologia e Dialisi, Azienda Ospedaliera Brotzu, Cagliari, Italy
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PO:32:178 | Effectiveness of oral anticoagulants in precapillary pulmonary hypertension associated with systemic sclerosis: a EUSTAR cohort study Nicola Farina1, Silvia Bellando-Randone1, Hilde Jenssen-Bjørkekjær2, David Launay3, Patricia Carreira4, Paolo Airò5, Serena Guiducci1, Dilia Giuggioli6, Gabriela Riemekasten7, Carmen-Pilar Simeón Aznar8, Christina Bergmann9, Elise Siegart10, Ivan Castellví11, Lesley Ann Saketkoo12, Jeska De Vries-Bouwstra13, Philipp Klemm14, Ulf Müller-Ladner14, Alexandra Balbir-Gurman15, Vanessa Smith16, Florenzo Iannone17, Luca Idolazzi18, Christopher Denton19, Edoardo Rosato20, Britta Maurer1, Yannick Allanore1, Yoshiya Tanaka1, Elisabetta Zanatta1, Oliver Distler1, Marco Matucci-Cerinic1, Cosimo Bruni1 | 1Department of Experimental and Clinical Medicine, Scleroderma Unit, Division of Rheumatology, University of Florence, Az Firenze, Italy; 2Department of Rheumatology, Hospital of Southern Norway Kristiansand, Norway; 3National Reference Center for Pulmonary Arterial Hypertension Pulmotension Lille, France; 4Hospital Universitario 12 de Octubre, Rheumatology Department Madrid Spain; 5ASST Spedali Civili of Brescia, University of Brescia, Rheumatology and Clinical Immunology Unit Brescia, Italy; 6Scleroderma Unit, Rheumatology Unit, University Hospital of Modena and Reggio Emilia Modena, Italy; 7Universitätsklinikum Schleswig-Holstein, Klinik für Rheumatologie und klinische Immunologie Lübeck Germany; 8Hospital Universitario Vall d'Hebron, Department of Internal Medicine, Systemic Autoimmune Diseases Unit Barcelona Spain; 9University Hospital Erlangen, Department Internal Medicine 3 Erlangen Germany; 10Charité University Hospital, Department of Rheumatology Berlin Germany; 11Hospital de la Santa Creu i Sant Pau Baercelona Spain; 12New Orleans Scleroderma and Sarcoidosis Patient Care and Research Center New Orleans, USA; 13Leiden University Medical Center, Department of Rheumatology Leiden, The Netherlands; 14JLU Giessen, Campus Kerckhoff, Department of Rheumatology and Clinical Immunology Center Bad Nauheim Germany; 15Rambam Health Care Campus, Rheumatology Institute Haifa, Israel; 16University of Ghent, Department of Rheumatology Ghent, Belgium; 17Rheumatology DiMePReJ, University of Bari, School of Medicine Bari, Italy; 18University of Verona, Section of Rheumatology, Department of Medicine Verona, Italy; 19Royal Free London and University College London Medical School, Centre for Rheumatology London, United Kingdom; 20Sapienza University of Rome, Department of Translational and Precision Medicine Azienda Ospedaliero-Universitaria Policl Roma, Italy
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PO:13:188 | Menstrual alterations among women with rheumatoid arthritis: a comparative study across treatment modalities with focus on JAK inhibitors Angelica Napoletano1, Francesca Arezzo2, Marco Fornaro1, Giuseppe Lopalco1, Gennaro Cormio2, Vincenzo Venerito1, Florenzo Iannone1. | 1University of Bari, Rheumatology Unit Department of Precision and Regenerative Medicine, Jonica Area, Bari; 2Gynecologic Oncology, IRCCS Istituto Tumori Giovanni Paolo II, Bari, Italy.
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PO:30:160 | A rare case of juvenile systemic sclerosis Marta Arese1|2, Francesco Baldo3, Stefania Costi3, Achille Marino3, Cecilia Chighizola1|3, Roberto Felice Caporali1|2 | 1Azienda Ospedaliera Universitaria Senese, Università degli Studi di Siena; 2Reumatologia Clinica, ASST Gaetano Pini-CTO, Milano, Italy
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PO:18:271 | Managing concomitant sle and psoriasis: the role of anifrolumab in a clinical case Angela Carenza1, Liliana Dinoia2, Sergio De Gioia2, Federica Gatti1, Teresa Caferri1, Lucia Cristiana Colaprico1, Angelica Napoletano1, Giuseppe Lopalco1, Florenzo Iannone1. | 1Rheumatology Unit, University of Bari, Department of Precision and Regenerative Medicine, Jonian area DiMePRe-J, Bari, Italy; 2Azienda Sanitaria Locale di Taranto, presidio ospedaliero SS. Annunziata, Unità Operativa di Reumatologia, Taranto, Italy.
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PO:08:126 | Use of upadacitinib in real-life: the experience of Calabrian rheumatology Vincenzo Raimondo1, Maurizio Caminiti2, Pietro Gigliotti3, Giuseppe Varcasia4, Massimo L'Andolina5, Domenico Olivo6, Roberta Pellegrini7, Pietro Muto8, Marilena Calabria9, Laura Massaro10, Jessica Maria El Luppino11, Salvatore De Bonis12, Giuseppa Pagano Mariano2, Stefania Sorbara3, Virginia Caira4, Mariateresa Cirillo5, Caterina Bruno9, Clodoveo Ferri11 | 1UOC di Reumatologia, Dipartimento SCIAC, Sapienza Università di Roma; 2Dipartimento di Medicina, Clinica di Reumatologia, Università degli Studi di Udine; 3UOC Medicina Interna e Nefrologia, Dipartimento MeSVA, Università degli Studi di L'Aquila; 4UniCamillus, San Camillo Università Internazionale di Scienze della Salute di Roma, Italy; 5Ambulatorio di Reumatologia, Ospedale di Tropea, Tropea, Italy; 6ASP Crotone, Ambulatorio di Reumatologia, Crotone, Italy; 7Ambulatorio di Reumatologia, Ospedale Annunziata di Cosenza, Cosenza, Italy; 8Ambulatorio di Reumatologia, Ospedale di Paola, Paola, Italy; 9Ambulatorio di Reumatologia, SOC di Medicina Interna, AOU Dulbecco, Catanzaro, Italy; 10Ambulatorio di Reumatologia, Ospedale di Praia a Mare, Praia a Mare, Italy; 11Casa di Cura Madonna dello Scoglio, Reparto di Reumatologia, Cotronei, Italy - Affiliazione 12: Ambulatorio di Reumatologia, ospedale di Acri, Acri, Italy
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PO:35:227 | Long-term renal and survival outcomes in microscopic polyangiitis: data from an observational monocentric cohort Roberta Prevedello1, Federica Davanzo1, Luca Iorio1, Eleonora Fiorin1, Marta Codirenzi1, Roberto Padoan1, Andrea Doria1. | 1Unità di Reumatologia, Dipartimento di Medicina DIMED, Università degli Studi di Padova, Padova, Italy.
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PO:02:018 | After-SECs: clinical predictors of secukinumab retention in psoriatic arthritis patients with inadequate response to anti-tumor necrosis factor therapy Francesco Cristiano1, Davide Gaspare Patti1, Valentina Boni1, Stefano Di Murro1, Cesare Gavotti1, Roberta Masnata1, Giulia Calabrese2, Gerlando Natalello2, Giusy Peluso2, Augusta Ortolan1|2, Enrico De Lorenzis1|2, Maria Antonietta D'Agostino1|2. | 1Università Cattolica del Sacro Cuore, Roma, Italy; 2Divisione di Reumatologia ed Immunologia clinica, Fondazione Policlinico Universitario A. Gemelli IRCCS, Roma, Italy.
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CO:07:5 | Enhanced fibroblast signatures in females with early rheumatoid arthritis highlights a potential basis for poorer treatment outcomes Benedetta Monosi1, James Perera2, Alessandra Nerviani2|3, Maria Sole Chimenti1, Felice Rivellese2|3, Costantino Pitzalis2|3|4. | 1Rheumatology, Allergology and Clinical Immunology, Department of Systems Medicine, University of Rome Tor Vergata, Rome, Italy; 2Centre for Experimental Medicine and Rheumatology, William Harvey Research Institute, Queen Mary University of London, London, UK; 3Barts Health NHS Trust and Barts Biomedical Research Centre, National Institute for Health and Care Research, London, UK; 4Department of Biomedical Sciences Humanitas University and IRCCS Humanitas Research Hospital, Milano, Italy
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PO:17:252 | The choice between belimumab and anifrolumab: analysis of a monocentric cohort Fabio Congiu1, Elisabetta Chessa2, Giulia Rizzo1, Elena Ragusa1, Marta Paola Pireddu1, Alessandra Oliva1, Marianna Salis1, Mattia Congia2, Maria Maddalena Angioni1, Micaela Rita Naitza1, Alberto Floris2, Alberto Cauli1|2, Matteo Piga1|2 | 1AOU e Università degli studi di Cagliari; 2SC Reumatologia PO Duilio Casula, Cagliari, Italy
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PO:37:268 | Antineutrophil cytoplasmic antibodies-associated vasculitis mimicking giant cell arteritis: a diagnostic dilemma Bruno Biasi1, Elena Vanni1, Marco De Pinto2, Giulia Cassone2, Dilia Giuggioli1|2. | 1Rheumatology Unit, School of Medicine, University of Modena and Reggio Emilia, Modena, Modena, Italy; 2Rheumatology Unit, Azienda Ospedaliera-Universitaria Policlinico di Modena, Modena, Italy, Modena, Italy.
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