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PO:06:083 | Clinical characteristics and outcomes of late- and young-onset rheumatoid arthritis in relation to autoantibody status Federica Sabatelli1|2, Ludovico De Stefano1|2, Clelia Zampaglione1|2, Lisa Bergianti1|2, Blerina Xoxi1|2, Antonio Manzo1|2, Carlomaurizio Montecucco1|2, Serena Bugatti1|2. | 1Department of Internal Medicine and Therapeutics, University of Pavia, Pavia; 2Division of Rheumatology, IRCCS Policlinico San Matteo Foundation, Pavia, Italy.
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PO:21:021 | The eyes tell the story: a clinical case of Rosah syndrome Nicolò Sabbion1, Sofia Vitale1, Claudia Balicchia1, Barbara Troise1, Francesca Mascia1, Eleonora Bassanello2, Jacopo Croce2, Federica Maiolini2, Filippo Mazzi2, Elisa Tinazzi2, Francesca Bosello1, Simonetta Friso1, Lucia De Franceschi1 | 1Università degli Studi di Verona; 2Azienda Ospedaliera Universitaria Integrata, Verona, Italy
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PO:22:029 | Impact of mepolizumab on idiopathic hypereosinophilic syndromes: analysis of a monocentric retrospective cohort Jacopo Mora1, Francesca Regola1, Paola Toniati2, Ilaria Cavazzana1, Franco Franceschini1. | 1ASST Spedali Civili e Università degli Studi di Brescia, Brescia, Italy; 2ASST Spedali Civili di Brescia, Brescia, Italy.
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PO:24:063 | Interstitial lung disease in idiopathic inflammatory myopathy patients: efficacy and safety of nintedanib Giulia Buonsante1|2|3, Giacomo De Luca1|2|3, Veronica Batani1|2, Lorenzo Dagna1|2|3, Marco Matucci-Cerinic1|2|3, Corrado Campochiaro1|2|3 | 1Unit of Immunology, Rheumatology, Allergy and Rare Diseases UNIRAR, IRCCS San Raffaele Hospital Milano, Italy; 2Inflammation, Fibrosis and aging Initiative INFLAGE, IRCCS San Raffaele Hospital Milano, Italy; 3Vita-Salute San Raffaele University, Milano, Italy
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PO:07:111 | Worsening of patient-reported outcomes is an early predictor of disease flare in patients with rheumatoid arthritis in course of treatment with conventional synthetic disease modifying anti-rheumatic drugs Ludovico De Stefano1|2, Federica Sabatelli1|2, Clelia Zampaglione1|2, Blerina Xoxi2, Antonio Manzo1|2, Carlomaurizio Montecucco1|2, Serena Bugatti1|2. | 1Department of Internal Medicine and Therapeutics, University of Pavia, Pavia, Italy; 2Division of Rheumatology, IRCCS Policlinico San Matteo Foundation, Pavia, Italy.
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PO:07:101 | Efficacy and safety of methotrexate in a cohort of patients affected by early-onset rheumatoid arthritis: a monocentric real-life study Carlo Cauli1, Martina Favretti2, Giulio Dolcini2, Vincenzo Ferraro1, Cristina Iannuccelli3, Fabrizio Conti1, Manuela Di Franco1 | 1UOC Reumatologia, Dipartimento di scienze cliniche internistiche anestesiologiche e cardiovascolari, Sapienza, Roma; 2Dipartimento di Medicina Molecolare, La Sapienza, Roma; 3UOC Reumatologia, AOU Policlinico Umberto I, La Sapienza, Roma, Italy
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PO:20:004 | Increase in serum Dkk1 levels attenuates the anabolic response to romosozumab in postmenopausal osteoporosis Giovanni Adami1, Filippo Montanari1, Angelo Fassio1, Francesco Pollastri1, Anna Piccinelli1, Davide Gatti1, Ombretta Viapiana1, Maurizio Rossini1. | 1Università degli Studi di Verona, Verona, Italy.
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PO:12:186 | Clinical, functional, and microvascular features in the early diagnosis and management of pulmonary hypertension in systemic sclerosis: the importance of multimodal screening strategies Irene Carlino1, Stefania Bisogno1, Alberto Palazzuoli2, Luigi Gennari1 | 1U.O.C. Reumatologia, Dipartimento di Scienze Mediche, Chirurgiche e Neuroscienze, Università di Siena, A.O.U. Senese; 2Azienda Sanitaria Locale, Novara, Italy
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PO:36:244 | Early diagnosis in eosinophilic granulomatosis with polyangiitis: a multidisciplinary approach Federico Giuseppe Lazzaro1, Elena Chiaradia2, Chiara Lombardi2, Flavia Leone1, Massimo Nucci2, Roberta Masnata2, Flora Niedda2, Maria Rita Gigante1, Pietro Rubortone1, Silvia Laura Bosello1|2, Maria Antonietta D'Agostino1|2, Augusta Ortolan1|2. | 1Divisione di Reumatologia ed Immunologia Clinica, Fondazione Policlinico Universitario A. Gemelli IRCCS, Roma, Italy; 2Università Cattolica del Sacro Cuore, Roma, Italy.
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CO:03:1 | Distinct breath metabolomic signature in systemic sclerosis patients with pulmonary arterial hypertension Martina Iacubino1, Lorenzo Rocco1, Marco Vicenzi2|3, Chiara Bellocchi2|4, Marta Mozzo4, Adriana Severino3, Monica Caronni3, Alessandro Santaniello3, Gaia Montanelli3, Barbara Vigone3, Liam Grimmett5, Matthew Kerr5, Lorenzo Beretta3. | 1Scuola di specializzazione in Allergologia e Immunologia clinica, Università degli Studi di Milano; 2Dipartimento di Scienze Cliniche e Salute di Comunità, Dipartimento di Eccellenza 2023-2027, Università degli Studi di Milano; 3Dipartimento di Malattie Cardio-Toraciche-Vascolari, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milano; 4Dipartimento di Immunologia Clinica e Medicina Interna, Scleroderma Unit - Fondazione IRCCS Ca' Granda Ospedale Maggiore, Milano, Italy; 5Owlstone Medical, Cambridge, UK
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PO:35:218 | Switching the dose of mepolizumab in patients with Eosinophilic Granulomatosis with Polyangiitis (EGPA): a European retrospective multicentre real-world study Edoardo Biancalana1, Irene Mattioli1, Emanuele Chiara2, Danilo Malandrino1, Maria Canfora1, Palmerini Miki1, Maria Paola Lisi1, Michela Gasparotto3, Paola Tomietto3, Maria Letizia Urban1, Giacomo Bagni1, Elena Silvestri1, Alessandra Bettiol3, Augusto Vaglio3, Giacomo Emmi2 | 1Department of Experimental and Clinical Medicine, University of Florence Firenze, Italy; 2Department of Medical, Surgery and Health Sciences, University of Trieste Trieste, Italy; 3Clinical Medicine and Rheumatology Unit, Cattinara University Hospital, Trieste, Trieste, Italy; 4Department of Biomedical, Experimental and Clinical Sciences Mario Serio, University of Florence Firenze, Italy
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PO:06:092 | Early achievement of remission confers better outcomes than low disease activity in both seropositive and seronegative patients with new-onset rheumatoid arthritis Clelia Zampaglione1|2, Ludovico De Stefano1|2, Federica Sabatelli1|2, Alessio D'Isanto1|2, Blerina Xoxi1|2, Antonio Manzo1|2, Carlomaurizio Montecucco1|2, Serena Bugatti1|2. | 1Department of Internal Medicine and Therapeutics, University of Pavia, Pavia; 2Division of Rheumatology, IRCCS Policlinico San Matteo Foundation, Pavia, Italy.
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CO:07:1 | Assessing bone fragility in systemic sclerosis: results of the Sclerobone multicentric study Giammarco De Mattia1, Cristina Di Nicola2, Davide Rozza2, Manuel Sette3, Veronica Gerli3, Ludovica Pisapia1, Chiara Sgorbini1, Giulia Botticella4, Pamela Bernardini5, Francesca Bottazzi6, Francesca Lalli8, Luca Idolazzi7, Laura Bogliolo6, Monica Cesarotti8, Alessandra Rossi1, Alessandra Della Rossa1, Andrea Giusti4, Serena Guiducci5, Carlo Alberto Scirè2, Addolorata Corrado9, Nicoletta Del Papa3, Marta Mosca1, Chiara Crotti3, Maurizio Rossini7, Maurizio Mazzantini1. | 1UO Reumatologia, Dipartimento di Specialità Mediche e Chirurgiche, Azienda Ospedaliero-Universitaria Pisana, Pisa; 2Centro Studi SIR, Società Italiana di Reumatologia, Milano; 3UO Reumatologia, ASST Gaetano Pini-CTO, Milano; 4SC Reumatologia, Ospedale La Colletta, Azienda Sanitaria Locale 3 Liguria, Arenzano (GE); 5SOD Reumatologia, Azienda Ospedaliero-Universitaria Careggi, Firenze; 6SC Reumatologia, Fondazione IRCCS Policlinico San Matteo, Pavia; 7UOC Reumatologia, Azienda Ospedaliera Universitaria Integrata di Verona; 8SSD Reumatologia, Azienda Sanitaria Locale Perugia; 9Clinica Reumatologica Universitaria, Azienda Ospedaliero Universitaria di Foggia, Italy
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PO:17:252 | The choice between belimumab and anifrolumab: analysis of a monocentric cohort Fabio Congiu1, Elisabetta Chessa2, Giulia Rizzo1, Elena Ragusa1, Marta Paola Pireddu1, Alessandra Oliva1, Marianna Salis1, Mattia Congia2, Maria Maddalena Angioni1, Micaela Rita Naitza1, Alberto Floris2, Alberto Cauli1|2, Matteo Piga1|2 | 1AOU e Università degli studi di Cagliari; 2SC Reumatologia PO Duilio Casula, Cagliari, Italy
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PO:10:150 | A case of pulmonary hypertension in Whipple's disease Alba Chiara Pozzi1|2, Giulia Fontana1|2, Francesca Crisafulli1|2, Guarino Daniele3, Monica Salvi3, Massimiliano Palazzini3, Francesco Biagi4|5, Ilaria Cavazzana1|2, Franco Franceschini1|2, Micol Frassi1. | 1Rheumatology and Clinical Immunology Unit ERN-ReCONNECT, ASST Spedali Civili, Brescia, Italy; 2Department of Clinical Experimental Sciences, University of Brescia, Brescia; 3IRCCS Azienda Ospedaliero-Universitaria di Bologna, University of Bologna, Cardiology Unit, DIMEC, Bologna; 4University of Pavia, Department of Internal Medicine and Therapeutics, Pavia; 5Istituti Clinici Scientifici Maugeri IRCCS, Gastroenterology Unit of Pavia Institute, Pavia, Italy.
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CO:08:6 | Prevalence, incidence and survival in interstitial lung disease secondary to primary Sjögren’s syndrome. Results from the “EMERGE” longitudinal study Alessandra Rai1, Caterina Vacchi2, Stefania Cerri3, Roberta Eufrasia Ledda4, Giulia Cassone2, Dario Andrisani3, Filippo Gozzi3, Lucia Dardani1, Fabiola Atzeni5, Athina Patsoura3, Francesca Cozzini1, Marco Sebastiani6, Andreina Manfredi1. | 1USL-IRCCS Reggio Emilia, University of Modena and Reggio Emilia; 2Azienda Ospedaliero Universitaria Policlinico di Modena; 3 Pulmonology Unit, AOU Policlinico di Modena, University of Modena and Reggio Emilia; 4Radiology Unit, Azienda Ospedaliera di Parma, University of Parma; 5 Policlinico Gaetano Martino, University of Messina; 6Azienda Ospedaliera di Piacenza,University of Parma, Italy
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PO:28:126 | Effectiveness of the new AMEL system in the treatment of simple painful shoulder syndrome Antonietta Albanese1, Emilio Battisti1, Federico Filippi2 | 1Dipartimento SFTA, Università di Siena, Siena; 2Sanimed, Fisiomed, Vicenza, Italy
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PO:16:231 | Differential clinical features of systemic lupus erythematosus patients on biological therapies: insights from a monocentric cohort Pietro Francesco Pilo, Elisa Bellis, Claudia Garulli, Claudio Cruciani, Marta Saracco, Claudia Lomater, Elena Marucco, Gloria Crepaldi, Valeria Data, Annamaria Iagnocco, Mariele Gatto. | Academic Rheumatology Centre, Department of Clinical and Biological Sciences, University of Turin, AO Mauriziano, Torino, Italy.
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PO:12:180 | Echocardiographic screening of pulmonary hypertension in a multidisciplinary cohort of patients with interstitial lung disease Lorenzo Mattia Bianchessi1, Veronica Piccin1, Federica Sabatelli1, Lorenzo Cavagna1, Giovanni Zanframundo1, Domenicafederica Briganti2, Mauro Acquaro3, Stefano Ghio3, Domenico Sorace1, Valentina Vertui2, Ilaria Giana2, Andrea Patanè3, Veronica Codullo1 | 1UOC Reumatologia, Fondazione IRCCS Policlinico S. Matteo, Pavia; 2Centro Trapianti, Fondazione IRCCS Policlinico San Matteo, Pavia; 3UOC Cardiologia, Fondazione IRCCS Policlinico San Matteo, Pavia, Italy
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PO:35:228 | Polymyalgia rheumatica and giant cell arteritis induced by immune checkpoint inhibitors for cancer treatment: a systematic review and meta-analysis highlighting differences from the idiopathic forms Elvis Hysa1, Andrea Casabella2, Emanuele Gotelli1, Rosanna Campitiello1, Carlo Genova3, Enrica Teresa Tanda4, Carmen Pizzorni1, Alberto Sulli1, Vanessa Smith5, Marco Amedeo Cimmino6, Sabrina Paolino1, Maurizio Cutolo1. | 1Laboratory of Experimental Rheumatology and Academic Division of Clinical Rheumatology, Department of Internal Medicine, Genova, Italy; 2IRCCS Ospedale Policlinico San Martino, Genova, Italy; 3Academic Oncology Unit; IRCCS Ospedale Policlinico San Martino, Genova, Italy; 4UOC Medical Oncology Clinic 2, Department of Internal Medicine, University of Genova, Genova, Italy; 5Department of Internal Medicine, Ghent University, Department of Rheumatology, Ghent University Hospital, Ghent, Belgium; 6Rheumatology Outpatient Clinic, Villa Ravenna Chiavari Italy.
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PO:30:157 | Radiographic assessment of measurable osteoarticular damage in juvenile idiopathic arthritis (JIA) patients transitioning to adult care Serena Pastore4, Marta Klanmjsceck3, Andrea Guiotto1, Laura De Nardi5|6, Alessia Pin4, Lorenzo Cereser1|2, Andrea Taddio3|4, Luisa Occhipinti1, Luca Quartuccio1|2, Alberto Tommasini3|4, Alen Zabotti2 | 1Università degli Studi di Udine Udine, Italy; 2Ospedale Santa Maria della Misericordia Udine, Italy; 3Università degli Studi di Trieste Trieste, Italy; 4IRCCS Materno Infantile Burlo Garofolo Trieste, Italy; 5Università Tor Vergata Roma, Italy; 6Ospedale Pediatrico Bambino Gesù Roma, Italy
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PO:07:098 | Reasons for treatment failure and their synovial correlate among patients with difficult-to-treat rheumatoid arthritis Alessandro Giollo1, Mariangela Salvato1, Francesca Frizzera1, Kiren Khalid1, Lorenzo Di Luozzo1, Carlo Garaffoni2, Maria Capita2, Marianna Tamussin2, Giovanni Lanza2, Marny Fedrigo3, Annalisa Angelini3, Roberta Ramonda1, Ettore Silvagni2, Andrea Doria1 | 1UOC Reumatologia Padova, Italy; 2UOC Reumatologia Ferrara, Italy; 3UOC Patologia cardiovascolare Padova, Italy; 4UOC Anatomia Patologica Ferrara, Italy
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PO:31:165 | Prevalence and incidence of skin telangectasia and their association with clinical features: analysis of the European Scleroderma Trials and Research cohort Gemma Lepri1, Lorenzo Tofani2, Silvia Bellando Randone1, Veronica Batani3, Paolo Airò4, Patricia Carreira5, Joerg Henes6, Alexandra Balbir Gurman7, Florenzo Iannone8, Antonella Marcoccia9, Luc Mouthon10, Branimir Anic11, Carolina De Souza Müller12, Armine Haroyan13, Ana Cristina Cordeiro14, Serena Guiducci And Eustar Coll1. | 1University of Florence, Dept of Experimental and Clinical Medicine, AOU Careggi, Division of Rheumatology Florence Italy; 2University of Florence, Dept of Statistics, Informatics, Applications, Florence, Italy; 3Unit of Immunology, Rheumatology, Allergy and Rare Diseases UnIRAR, IRCCS San Raffaele, Milano, Italy; 4Scleroderma Unit, UOC Rheumatology and Clinical Immunology, ASST Spedali Civili, Brescia, Italy; 5Dept of Rheumatology, 12 de Octubre University Hospital, Madrid, Spain; 6Centre for Interdisciplinary Rheumatology, Immunology and autoimmune diseases INDIRA, University Hospital Tuebingen, Tuebingen, Germany; 7Rheumatology Institute, Rambam Health Care Campus Haifa Israel; 8Dept of Precision and Regenerative Medicine and Ionian Area, University of Bari, Bari, Italy; 9Interdisciplinary Reference Center for Systemic Sclerosis CRIIS Sandro Pertini Hospital, Rome, Italy; 10Dept of Internal Medicine, Cochin Hospital, Paris Cité University, Paris, France; 11Div Clinical Immunology and Rheumatology, Dept Internal Medicine, School of Medicine, University Hospital Center Zagreb, Zagreb, Croatia; 12Rheumatology Division, Hospital de Clínicas da Universidade Federal do Parana, Curitiba, Brazil; 13Dept of Rheumatology, Yerevan State Medical University of Armenia, Yerevan, Armenia; 14Servico Reumatologia Hospital Garcia de Orta Almada, Almada, Portugal.
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PO:31:171 | Uncovering subclinical cardiac involvement in VEDOSS: An echocardiographic driven study Eugenio Capparelli1, Eleonora Zaccara1, Irene Rota2, Sara Facetti2, Daniela Bompane1, Laura Castelnovo1, Antonino Mazzone3, Paola Faggioli1 | 1UOC Reumatologia, ASST Ovest-Milanese, Legnano Milano Italy; 2UOC Cardiologia, ASST Ovest-Milanese, Legnano Milano, Italy; 3UOC Medicina Interna, ASST Ovest-Milanese, Legnano, Milano, Italy
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PO:16:232 | Belimumab step-down dose spacing in patients with systemic lupus erythematosus in persistent clinical remission: experience from a multicentric cohort Alice Bartoletti1, Laura Giudice1, Lorenza Maria Argolini1|2, Giuseppe Alvise Ramirez3, Luca Moroni3, Tommaso Schioppo4, Chiara Bellocchi5|6, Annalaura Fasiello6, Lorenzo Beretta6, Lorenzo Dagna3, Roberto Caporali1, Maria Gerosa1. | 1UO Clinica Reumatologica, ASST Gaetano Pini CTO, Milano, Italy; 2UOC Medicina fisica e riabilitazione specialistica, ASST Gaetano Pini CTO, Milano, Italy; 3Unit of Immunology, Rheumatology, Allergy and Rare Diseases, IRCCS San Raffaele Hospital, Vita-Salute San Raffa Milano Italy; 4Medicina Generale II, Servizio di Reumatologia, Ospedale San Paolo, ASST Santi Paolo Carlo, Milano, Italy; 5Department of Clinical Sciences and Community Health, University of Milan, Dipartimeto di Eccellenza 2023-2027, Milano, Italy; 6Referral Centre for Systemic Autoimmune DIseases, Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico, Milano, Italy
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CO:08:1 | Aquaporin-4 downregulation in dysphagic idiopathic inflammatory myopathies: association with Type 2 fiber damage and inflammation Marco Fornaro1, Margherita Giannini2, Dario D'Abbicco3, Maria Luisa Fiorella4, Antonio Frigeri5, Francesco Girolamo6, Florenzo Iannone1. | 1Unit of Rheumatology, Department of Precision and Regenerative Medicine and Ionian Area, Bari, Italy; 2Physiologie et Explorations Fonctionnelles Musculaires, University Hospital of Strasbourg, Strasburgo, France; 3Institute of General Surgery G Marinaccio, Department of Precision and Regenerative Medicine and Ionian Area, Bari; 4Unit of Otolaryngology, Department of Translational Biomedicine and Neuroscience DiBraiN, Bari; 5Unit of Human Physiology, Department of Translational Biomedicine and Neuroscience DiBraiN, Bari; 6Unit of Human Anatomy and Histology, Department of Translational Biomedicine and Neuroscience DiBraiN, Bari, Italy
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