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PO:13:188 | Menstrual alterations among women with rheumatoid arthritis: a comparative study across treatment modalities with focus on JAK inhibitors Angelica Napoletano1, Francesca Arezzo2, Marco Fornaro1, Giuseppe Lopalco1, Gennaro Cormio2, Vincenzo Venerito1, Florenzo Iannone1. | 1University of Bari, Rheumatology Unit Department of Precision and Regenerative Medicine, Jonica Area, Bari; 2Gynecologic Oncology, IRCCS Istituto Tumori Giovanni Paolo II, Bari, Italy.
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PO:24:063 | Interstitial lung disease in idiopathic inflammatory myopathy patients: efficacy and safety of nintedanib Giulia Buonsante1|2|3, Giacomo De Luca1|2|3, Veronica Batani1|2, Lorenzo Dagna1|2|3, Marco Matucci-Cerinic1|2|3, Corrado Campochiaro1|2|3 | 1Unit of Immunology, Rheumatology, Allergy and Rare Diseases UNIRAR, IRCCS San Raffaele Hospital Milano, Italy; 2Inflammation, Fibrosis and aging Initiative INFLAGE, IRCCS San Raffaele Hospital Milano, Italy; 3Vita-Salute San Raffaele University, Milano, Italy
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PO:31:163 | Safety and tolerability of home-based prostacyclin analogue therapy in vascular manifestations of the scleroderma spectrum: results of a monocentric study Alice Dionisi1, Lucrezia Verardi2, Annacarla Finucci2, Paola Volpe2, Anna Cinzia Raspa2, Paola Cipriani1, Raffaele Zicolella2 | 1Reumatologia,Dipartimento di Sscienze Cliniche Applicate e Biotecnologiche, Università degli Studi dell'Aquila; 2UOC Reumatologia, Ospedale Civile di Pescara, Italy
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Adherence to vaccination against SARS-CoV-2 and vaccine safety in patients with IgG4-related disease
1631PDF: 197SUPPLEMENTARY MATERIAL: 75 -
CO:09:3 | Effectiveness and safety of nintedanib in autoimmune systemic diseases: real life data from an Italian multicentre study (Island group) of the Italian Society of Rheumatology Corrado Campochiaro1, Paola Conigliaro2, Gianluca Sambataro3, Marco Matucci-Cerinic1, Marco Sebastiani4, Gianluca Bajocchi5, Angelo Fassio6, Elena Treppo7, Elisabetta Zanatta8, Elena Bartolini9, Francesco Ferro10, Chiara Bazzini11, Nicoletta Del Papa12, Gemma Lepri13, Andrea Lo Monaco14, Marta Favero15, Annamaria Iuliano16, Francesca Li Gobbi17, Maria Sole Chimenti2, Giuseppe Muscato18, Giacomo De Luca1, Francesca Cozzini4, Lucia Dardani5, Francesco Pollastri6, Alessandro Gattron7, Beatrice Moccaldi8, Caterina Antonini9, Gaetano La Rocca10, Ilaria Cavazzana11, Andreina Manfredi5|19. | 1IRCCS San Raffaele Hospital, Vita-Salute San Raffaele, Milano; 2U.O.C. Reumatologia Dipartimento di Medicina dei Sistemi Università di Roma-Tor Vergata, Roma; 3Università Kore, Enna; 4University of Parma, Azienda Ospedaliera di Piacenza; 5UOC Reumatologia, AUSL IRCCS Reggio Emilia; 6UOC Reumatologia Università degli Studi di Verona; 7Dipartimento di Medicina, Clinica di Reumatologia, Università degli Studi di Udine; 8UOC Reumatologia, Dipartimento di Medicina DIMED, Azienda Ospedale Università di Padova; 9SC Interaziendale di Reumatologia, Dipartimento di Medicina e Chirurgia, Università di Perugia, Azienda Integrata Università; 10Dipartimento di Medicina Clinica e Sperimentale UO Reumatologia-Universitaria AOU Pisa; 11U.O. Reumatologia e Immunologia Clinica ASST Spedali Civili di Brescia; 12Clinica Reumatologica, Milano; 13S.O.D. di Reumatologia AOU Careggi, Firenze; 14UOC Reumatologia Azienda Ospedaliero-Universitaria Sant'Anna, Ferrara; 15Internal Medicine I, Department of Medicine, Ca' Foncello Hospital, AULSS2 Marca Trevigiana, Treviso; 16UOC Reumatologia, AO San Camillo Forlanini, Roma; 17Rheumatology Unit, S.Giovanni di Dio Hospital, Firenze; 18Department of Clinical and Experimental Medicine, Regional Referral Center for Rare Lung Disease, Policlinico, Catania; 19Università degli Studi di Modena e Reggio Emilia, Italy
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PO:06:078 | Is difficult-to-treat rheumatoid arthritis less severe in patients with autoantibody-negative disease? retrospective analysis from a monocentric cohort. Bernardo D'Onofrio1, Maria Chiara Ditto1, Francesco Ghellere1, Giacomo Tanti1, Salvatore Panaro1, Enrico Fusaro1, Simone Parisi1. | 1AOU Città della Salute e della Scienza, Torino, Italy.
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PO:35:234 | Sustained Vasculitis Quiescence and CS Reduction with Mepolizumab 100 mg Francesca Mascia1, Angelo Fassio2, Marco Zurlo1, Davide Chesini3, Francesco Pollastri2, Giovanni Adami2, Davide Gatti4, Maurizio Rossini4, Matteo Maule5, Gianentrico Senna1, Marco Caminati1 | 1University of Verona - Allergology and Clinical Immunology Verona, Italy; 2Policlinico G. B. Rossi - Rheumatology Verona, Italy; 3University of Verona - Faculty of Medicine and Surgery Verona, Italy; 4University of Verona - Rheumatology Verona, Italy; 5Policlinico G. B. Rossi - Allergology and Clinical Immunology Verona, Italy
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PO:16:236 | Achieving a low disease activity state with a corticosteroid dose of 5 mg or less: observational study with anifrolumab in patients with systemic lupus erythematosus in Italy Alessandra Bortoluzzi1, Fulvia Ceccarelli2, Fabio Leo3, Paola Roccatagliata3, Chiara Tani4, Margherita Zen5 | 1Azienda Ospedaliera Universitaria Sant' Anna di Cona, Università di Ferrara Italy; 2Unità di Reumatologia, Università Sapienza Roma Italy; 3AstraZeneca S.p.a. Milano Italy; 4Università di Pisa e Azienda Ospedaliero Universitaria Pisana, Pisa Italy; 5Dipartimento di Medicina DIMED , Divisione di Reumatologia, Università di Padova, Italy
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CO:09:6 | Risk of disease flare during pregnancy and postpartum in inflammatory arthritis: association with therapy discontinuation in the prospective P-RHEUM.it study Dina Zucchi1, Chiara Tani1, Francesca Crisafulli2, Alessia Gatti2, Maria Gerosa3, Cecilia Chighizola3, Melissa Padovan4, Salvatore D'Angelo5, Florenzo Iannone6, Maria Sole Chimenti7, Claudia Lomater8, Francesca Serale9, Veronique Ramoni10, Oscar Epis11, Bernd Raffeiner12, Ariela Hoxha13, Andrea Doria14, Leonardo Santo15, Valentina Canti16, Francesca Bellisai17, Giovanna Cuomo18, on behalf of the P-Rheumit Investigators19, Greta Carrara20, Cristina Di Nicola20, Davide Rozza20, Carlo Alberto Scirè20, Maria Chiara Gerardi11, Angela Tincani2, Laura Andreoli2, Marta Mosca1. | 1Rheumatology Unit, University of Pisa and Azienda Ospedaliero Universitaria Pisana; 2Rheumatology and Clinical Immunology Unit, ASST Spedali Civili, Brescia; 3Clinical Rheumatology Division, ASST Gaetano Pini-CTO and University of Milano; 4Rheumatology Unit, Azienda Ospedaliero-Universitaria S. Anna and University of Ferrara; 5Rheumatology Department of Lucania - San Carlo Hospital, Potenza; 6Rheumatology Unit, DiMePRE-J, University of Bari; 7Department of Systems Medicine, Rheumatology, Allergology and Clinical Immunology, University of Rome-Tor Vergata, Roma; 8Torino Academic Rheumatology Center, A.O. Mauriziano di Torino, University of Torino; 9Rheumatology Unit, ASL CN1 Cuneo; 10Internal Medicine Department, ASST Lodi - Ospedale Maggiore di Lodi; 11Division of Rheumatology, Multispecialist Medical Department, Grande Ospedale Metropolitano Niguarda, Milano; 12Department of Rheumatology, Central Hospital of Bolzano SABES-ASDAA, Bolzano; 13General Medicine and Thrombosis and Hemorrhagic Unit, Department of Medicine, University of Padova; 14Rheumatology Unit, Department of Medicine, University of Padova; 15Rheumatology Unit, Mons. Dimiccoli Hospital, Barletta; 16Division of Immunology, Transplantation and Infectious Diseases, IRCCS Ospedale San Raffaele, Milano; 17Rheumatology Unit, Department of Medicine, Surgery and Neurosciences, University of Siena; 18Precision Medicine Department, University of Campania L. Vanvitelli, Napoli; 19The Italian Society for Rheumatology; 20Epidemiology Research Unit of the Italian Society for Rheumatology, Milano, Italy
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PO:25:079 | Anifrolumab in refractory dermatomyositis: a case report Chiara Calabrese1, Corrado Campochiaro1|2, Giacomo De Luca 1|2, Veronica Batani1, Marco Matucci-Cerinic1|2, Lorenzo Dagna 1|2 | 1Dipartimento di Reumatologia e Scienze Mediche, ASST Centro Specialistico Ortopedico Traumatologico Gaetano Pini-CTO Milano; 2Università degli Studi di Milano, Dipartimento di Fisiopatologia Medico-Chirurgica e Trapianti, Milano, Italy
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PO:06:089 | Heat-not-burn cigarettes induce protein post-translational modifications (PTM): possible role in the pathogenesis of rheumatoid arthritis Claudia Ciancarella1, Federica Maria Ucci1, Valeria Manganelli2, Elena Fasciolo2, Roberta Priori1, Fulvia Ceccarelli1, Manuel Sergi3, Camilla Montesano3, Francesco Bartolini3, Maurizio Sorice2, Cristiano Alessandri1, Fabrizio Conti1 | 1Rheumatology Unit, Department of Internal Medicine, Anesthesiology and Cardiovascular Sciences, La Sapienza, Roma, Italy; 2Department of Experimental Medicine, La Sapienza University of Rome, Italy; 3Department of Chemistry, La Sapienza University Of Rome, Italy
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PO:17:255 | Efficacy and safety of voclosporin in the management of lupus nephritis: a case series Alessandra Oliva1, Elisabetta Chessa2, Marta Paola Pireddu1, Marianna Salis1, Giulia Rizzo1, Fabio Congiu1, Elena Ragusa1, Antonello Pani3|4, Alberto Cauli1|2, Nicola Lepori3|4, Matteo Piga1|2 | 1UOC Reumatologia, Dipartimento di Scienze Mediche e Salute Pubblica, Università degli Studi di Cagliari; 2UOC Reumatologia, AOU Cagliari; 3SC Nefrologia e Dialisi, Università degli Studi di Cagliari; 4SC Nefrologia e Dialisi, Azienda Ospedaliera Brotzu, Cagliari, Italy
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PO:16:225 | Belimumab in refractory and/or non-criteria manifestations of antiphospholipid syndrome: ad interim analysis on Quality-of-Life changes from the BLAST trial Alessio Conti1, Lois Ira Capulong1, Irene Cecchi1, Elena Rubini1, Chiara Bova1, Massimo Radin1, Alice Barinotti1, Beatrice Ala1, Silvia Grazietta Foddai1, Daniela Rossi1, Roberta Fenoglio1, Savino Sciascia1 | 1Centro di Eccellenza Universitario per le Malattie Nefrologiche, Reumatologiche e Rare, S.G.Bosco -ASL Città di Torino, Italy
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PO:07:099 | Survival on therapy of certolizumab pegol in rheumatoid arthritis, psoriatic arthritis, and spondyloarthritis: 8-year data from an Italian multicenter register Maria Manara1, Gilberto Cincinelli1|2, Marco Fornaro3, Simone Perniola4, Elisa Gremese5, Chiara Bazzani6, Serena Bugatti7, Francesca Romana Spinelli8, Rosario Foti9, Marco Sebastiani10, Alberto Cauli11, Fabiola Atzeni12, Giovanni Lapadula13, Gianfranco Ferraccioli14, Fabrizio Conti8, Florenzo Iannone3, Roberto Caporali1|2 | 1Department of Rheumatology and Medical Sciences, ASST G. Pini-CTO Milano; 2Department of Clinical Sciences and Community Health, University of Milan; 3Department of Precision and Regenerative Medicine and Ionian Area, University of Bari; 4Clinical Immunology Division, Fondazione Policlinico Universitario A. Gemelli IRCCS, Roma; 5Rheumatology and Clinical Immunology, IRCCS Humanitas Research Hospital, Rozzano (MI); 6Unit of Rheumatology and Clinical Immunology, ASST Spedali Civili Brescia; 7Department of Internal Medicine and Therapeutics, Università di Pavia; 8Rheumatology Unit, Dipartimento Scienze Cliniche Internistiche, Anestesiologiche e Cardiovascolari, Sapienza University, Roma; 9Rheumatology Unit, San Marco Hospital, Policlinico University of Catania; 10Rheumatology Unit, AUSL Piacenza, University of Parma; 11UOC di Reumatologia, Dipartimento di Scienze Mediche e Sanità Pubblica, Azienda Ospedaliero-Universitaria di Cagliari; 12Rheumatology Unit, Department of Experimental and Internal Medicine, University of Messina; 13Gruppo Italiano di Studio sulla Early Arthritis, GISEA, Bari; 14Department of Medicine, Università Cattolica del Sacro Cuore, Fondazione IRCCS Policlinico Gemelli, Roma, Italy
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PO:16:232 | Belimumab step-down dose spacing in patients with systemic lupus erythematosus in persistent clinical remission: experience from a multicentric cohort Alice Bartoletti1, Laura Giudice1, Lorenza Maria Argolini1|2, Giuseppe Alvise Ramirez3, Luca Moroni3, Tommaso Schioppo4, Chiara Bellocchi5|6, Annalaura Fasiello6, Lorenzo Beretta6, Lorenzo Dagna3, Roberto Caporali1, Maria Gerosa1. | 1UO Clinica Reumatologica, ASST Gaetano Pini CTO, Milano, Italy; 2UOC Medicina fisica e riabilitazione specialistica, ASST Gaetano Pini CTO, Milano, Italy; 3Unit of Immunology, Rheumatology, Allergy and Rare Diseases, IRCCS San Raffaele Hospital, Vita-Salute San Raffa Milano Italy; 4Medicina Generale II, Servizio di Reumatologia, Ospedale San Paolo, ASST Santi Paolo Carlo, Milano, Italy; 5Department of Clinical Sciences and Community Health, University of Milan, Dipartimeto di Eccellenza 2023-2027, Milano, Italy; 6Referral Centre for Systemic Autoimmune DIseases, Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico, Milano, Italy
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PO:37:260 | Mepolizumab in the treatment of patients with eosinophilic granulomatosis with polyangiitis: real-life experience from a single-center cohort Eleonora Bruschi1, Fabrizio Angeli1, Alessandro Belotti Masserini1, Stefania Bertocchi1, Silvia Breda1, Elide Lupi1, Valeria Rossi1, Tania Ubiali1, Massimiliano Limonta1 | 1ASST Papa Giovanni XXIII Bergamo Italy
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PO:06:086 | Updated Systematic Literature Review and meta-analysis to Inform the Italian Society of Rheumatology Recommendations on the Treatment of Rheumatoid Arthritis-Associated Interstitial Lung Disease Angelo Fassio1, Marco Sebastiani9|10, Francesco Pollastri1, Chiara Crotti4, Nicola Ughi5, Enrico De Lorenzis6, Silvia Mancuso7, Massimo Radin8, Francesca Cozzini9, Greta Carrara11, Gianpiero Landolfi11, Roberto Rozza11, Andreina Manfredi2|3 | 1Rheumatology Unit, University of Verona, Verona, Italy; 2University of Modena and Reggio Emilia, Reggio Emilia, Italy; 3Rheumatology Unit, AUSL-IRCCS, Reggio Emilia, Italy; 4Bone Disease Unit, Department of Rheumatology and Medical Science, ASST-G.Pini-CTO, Milan, Italy; 5Division of Rheumatology, Multispecialist Medical Department, ASST Grande Ospedale Metropolitano Niguarda, Milano, Italy; 6Department of Aging Diseases, Orthopedic and Rheumatology, Rheumatology Division, P. Gemelli, Roma, Italy; 7Rheumatology Unit, Department of Clinical, Internal, Anaesthesiologic and Cardiovascular, Sciences, Sapienza, Roma, Italy; 8CMID, San Giovanni Bosco Hub Hospital ASL Città di Torino and Department of Clinical and Biological Sciences, Turin, Italy; 9Department of Medicine and Surgery, University of Parma, Parma, Italy; 10Rheumatology Unit, AUSL Piacenza, Piacenza, Italy; 11Unità Epidemiologica, SIR, Società Italiana di Reumatologia, Milano, Italy
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PO:02:023 | Monocentric analysis of systemic glucocorticoids in PsA: the art of balancing prescriptive appropriateness and risk factor management Chiara Crotti1 2, Gilberto Cincinelli1, Giorgia Trignani13, Luca Ingrao13, Miriam Perino13, Roberto Caporali13 | 1Dipartimento di Reumatologia e Scienze Mediche - UOC Clinica Reumatologica, ASST Pini-CTO, Milano; 2Dipartimento di Reumatologia e Scienze Mediche - UOC Osteoporosi e Malattie Metaboliche dell Osso - ASST Pini-CTO, Milano; 3Dipartimento di Scienze Cliniche e di Comunità - Università degli Studi di Milano, Italy
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PO:26:087 | Rituximab versus glucocorticoids for IgG4-related disease: a European retrospective multi-center study of 167 patients Marco Lanzillotta1, Jens Vikse2, Elisabetta Goni3, Jasmin Mahajne1, Veronica Batani1, Lorenzo Dagna1, Emanuel Della-Torre1 | 1Unit of Immunology, Rheumatology, Allergy, and Rare Disease, IRCCS Ospedale san Raffaele Milano, Italy; 2Department of Rheumatology, Stavanger University Hospital, Stavanger, Norway; 3Department of Medicine II, University Hospital, Ludwig Maximilian University Munich, Munich Germany
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PO:02:022 | Bimekizumab Maintained Stringent Clinical Responses over 2 Years in Patients with Axial Spondyloarthritis: Results from Two Phase 3 Studies Fabian Proft1, Désirée Van Der Heijde2, Sergio Schwartzman3|4|5, Joerg Ermann6, Alexander Marten7, Ute Massow7, George Stojan8, Vanessa Taieb9, Diana Voiniciuc10, Astrid Van Tubergen11, Victoria Navarro-Compán12, Simone Angioni13, Xenofon Baraliakos14 | 1Charité-Universitätsmedizin Berlin; Freie Universität Berlin and Humboldt-Universität zu Berlin, Berlin, Germany; 2Department of Rheumatology, Leiden University Medical Center Leiden, The Netherlands; 3Weill Cornell Medical Center New York, USA; 4New York Presbyterian Hospital New York, USA; 5Hospital for Special Surgery New York, USA; 6Division of Rheumatology, Inflammation and Immunity, Brigham and Women's Hospital and Harvard Medical School Boston, USA; 7UCB Monheim am Rhein Germany; 8UCB Atlanta, USA; 9UCB Colombes, France; 10UCB Slough, United Kingdom; 11Department of Medicine, Division of Rheumatology, Maastricht University Medical Center Maastricht, The Netherlands; 12Department of Rheumatology, La Paz University Hospital, IdiPaz Madrid, Spain; 13UCB Milan, Italy; 14Rheumazentrum Ruhrgebiet Herne, Ruhr-University Bochum, Germany
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PO:05:074 | A clinical case of a patient affected by long-standing psoriatic arthritis and multiple comorbidities treated with an anti-IL-23 therapy Maria Letizia Currò1, Angelo Tropea1, Alessandra Burgio1, Francesca Cracò1, Antonio Pezzano1, Federica Rapisarda1, Antonino Palumbo1, Valeria D'Amico1, Fabiola Atzeni1 | 1Clinica Reumatologica di Udine, Dipartimento di Medicina, ASUFC, Udine, Italy
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PO:18:268 | Voclosporin as a Steroid-Sparing Agent in Lupus Nephritis Complicated by Central Serous Chorioretinopathy: A Case Report Irene Genovali1|2, Sebastiano Lorusso2, Damiano Currado1|2, Letizia Pia Di Corcia1, Ludovica Lamberti1, Annalisa Marino2, Antonio Orlando1, Maria Quadrini1, Marta Vadacca2, Marta Vomero1, Luca Navarini1|2, Roberto Giacomelli1|2 | 1Rheumatology and Clinical Immunology, Department of Medicine, University of Rome Campus Biomedico, School of Medicine Rome, Italy; 2Clinical and Research Section of Rheumatology and Clinical Immunology Fondazione Policlinico Campus Biomedico Rome, Italy
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PO:29:138 | Cetylated fatty acids and fibromyalgia: efficacy and tolerability in a prospective study Anna Capogna1, Marco Bardelli1, Luca Cantarini1, Bruno Frediani1 | 1UOC Reumatologia, Dipartimento di Scienze mediche, chirurgiche e neuroscienze, Università degli Studi di Siena, Italy
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PO:03:033 | Low Uveitis Rates in Patients with Axial Spondyloarthritis or Psoriatic Arthritis Treated with Bimekizumab: Long-Term Results from Phase 2b/3 Trials Irene E Van Der Horst-Bruinsma1, Matthew A Brown2, Floris A Van Gaalen3, Nigil Haroon4, Lianne S Gensler5, Alexander Marten6, Myriam Manente7, George Stojan8, Thomas Vaux9, Katy White9, Atul Deodhar10, Nicola Boffini11, Martin Rudwaleit12 | 1Department of Rheumatology, Radboud University Medical Centre Nijmegen, The Netherlands; 2Genomics England London, United Kingdom; 3Department of Rheumatology, Leiden University Medical Center Leiden, The Netherlands; 4Department of Medicine/Rheumatology, University Health Network, Schroeder Arthritis Institute, University of Toronto Toronto, Canada; 5Department of Medicine/Rheumatology, University of California San Francisco, USA; 6UCB Monheim am Rhein Germany; 7UCB Braine-lAlleud, Belgium; 8UCB Atlanta, USA; 9UCB Slough, United Kingdom; 10Division of Arthritis and Rheumatic Diseases, Oregon Health and Science University Portland, USA; 11IRCCS Ospedale San Raffaele Milan, Italy; 12Klinikum Bielefeld, University of Bielefeld, Bielefeld, Germany
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