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S13:6 | Investigating the intricate interplay between pulmonary functionality and advanced microangiopathy in very early diagnosis of systemic sclerosis Eugenio Capparelli1, Eleonora Zaccara1, Daniela Bompane1, Elisabetta Ricchiuto2, Giorgio Bonardi2, Laura Castelnovo1, Antonio Tamburello1, Antonino Mazzone3, Paola Faggioli1. | 1Rheumatology Unit; 2Pneumology Unit; 3Internal Medicine Unit, ASST Ovest Milanese, Legnano, Italy.
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PO:02:022 | Bimekizumab Maintained Stringent Clinical Responses over 2 Years in Patients with Axial Spondyloarthritis: Results from Two Phase 3 Studies Fabian Proft1, Désirée Van Der Heijde2, Sergio Schwartzman3|4|5, Joerg Ermann6, Alexander Marten7, Ute Massow7, George Stojan8, Vanessa Taieb9, Diana Voiniciuc10, Astrid Van Tubergen11, Victoria Navarro-Compán12, Simone Angioni13, Xenofon Baraliakos14 | 1Charité-Universitätsmedizin Berlin; Freie Universität Berlin and Humboldt-Universität zu Berlin, Berlin, Germany; 2Department of Rheumatology, Leiden University Medical Center Leiden, The Netherlands; 3Weill Cornell Medical Center New York, USA; 4New York Presbyterian Hospital New York, USA; 5Hospital for Special Surgery New York, USA; 6Division of Rheumatology, Inflammation and Immunity, Brigham and Women's Hospital and Harvard Medical School Boston, USA; 7UCB Monheim am Rhein Germany; 8UCB Atlanta, USA; 9UCB Colombes, France; 10UCB Slough, United Kingdom; 11Department of Medicine, Division of Rheumatology, Maastricht University Medical Center Maastricht, The Netherlands; 12Department of Rheumatology, La Paz University Hospital, IdiPaz Madrid, Spain; 13UCB Milan, Italy; 14Rheumazentrum Ruhrgebiet Herne, Ruhr-University Bochum, Germany
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CO:01:2 | BAG3 in systemic sclerosis: possible therapeutic target and biomarker for pulmonary fibrosis Claudia Iannone1|2, Margot De Marco3, Antonina Minniti1, Paola Manzo3, Angela D'Ardia3, Antonia Falco3, Liberato Marzullo3, Angela Rosato3, Maria Caterina Turco3, Roberto Caporali1|2, Nicoletta Del Papa1|2. | 1ASST G. Pini-CTO. UOC Clinica Reumatologica, Milano; 2Department of Clinical Sciences and Community Health, University of Milano; 3Department of Medicine, Surgery and Dentistry Schola Medica Salernitana, Baronissi (SA), Italy
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PO:35:221 | Cryofibrinogen: a cold case. Characteristics and clinical outcomes from a cryofibrinogen positive cohort Daniele Catameró1, Andrea Cito1, Cristiana Colaprico1, Teresa Caferri1, Teresa Troiano1, Anna Marinaccio1, Marco Fornaro1, Giuseppe Lopalco1, Florenzo Iannone1. | 1Unit of Rheumatology , Department of Precision and Regenerative Medicine, Area Jonica DiMePRe-J, University of Bari, Bari, Italy.
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PO:35:234 | Sustained Vasculitis Quiescence and CS Reduction with Mepolizumab 100 mg Francesca Mascia1, Angelo Fassio2, Marco Zurlo1, Davide Chesini3, Francesco Pollastri2, Giovanni Adami2, Davide Gatti4, Maurizio Rossini4, Matteo Maule5, Gianentrico Senna1, Marco Caminati1 | 1University of Verona - Allergology and Clinical Immunology Verona, Italy; 2Policlinico G. B. Rossi - Rheumatology Verona, Italy; 3University of Verona - Faculty of Medicine and Surgery Verona, Italy; 4University of Verona - Rheumatology Verona, Italy; 5Policlinico G. B. Rossi - Allergology and Clinical Immunology Verona, Italy
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PO:10:150 | A case of pulmonary hypertension in Whipple's disease Alba Chiara Pozzi1|2, Giulia Fontana1|2, Francesca Crisafulli1|2, Guarino Daniele3, Monica Salvi3, Massimiliano Palazzini3, Francesco Biagi4|5, Ilaria Cavazzana1|2, Franco Franceschini1|2, Micol Frassi1. | 1Rheumatology and Clinical Immunology Unit ERN-ReCONNECT, ASST Spedali Civili, Brescia, Italy; 2Department of Clinical Experimental Sciences, University of Brescia, Brescia; 3IRCCS Azienda Ospedaliero-Universitaria di Bologna, University of Bologna, Cardiology Unit, DIMEC, Bologna; 4University of Pavia, Department of Internal Medicine and Therapeutics, Pavia; 5Istituti Clinici Scientifici Maugeri IRCCS, Gastroenterology Unit of Pavia Institute, Pavia, Italy.
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CO:10:4 | Lung vasculature quantification on computed tomography predicts new onset of interstitial lung disease in systemic sclerosis Maria Iacovantuono1|2, Nicholas Landini2|3, Lisa Jungblut4, Gesa Sauer2, Rucsandra Dobrota2, Maria Sinziana Muraru-Carbune2, Muriel Elhai2, Carmen-Marina Mihai2, Mike Oliver Becker2, Maria Sole Chimenti1, Thomas Frauenfelder4, Anna-Maria Hoffmann-Vold5, Oliver Distler2, Cosimo Bruni2. | 1Rheumatology, Allergology and Clinical Immunology, Department of Systems Medicine, Tor Vergata University, Rome, Italy; 2Department of Rheumatology, University Hospital Zurich, University of Zurich, Switzerland; 3Department of Radiological Sciences, Oncology and Pathology, Sapienza University, Policlinico Umberto I, Rome, Italy; 4Institute for Diagnostic and Interventional Radiology, University Hospital Zurich, University Zurich, Switzerland; 5Department of Rheumatology, Oslo University Hospital, Norway
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PO:12:183 | Acute effect of anti-TNF therapy on atrioventricular conduction in chronic inflammatory arthritis: a prospective cohort study Viola Salvini1, Riccardo Accioli1, Anna Cantore1, Fabio Salvadori1, Enrico Selvi2, Virgina Berlengerio2, Maurizio Acampa3, Alessandra Cartocci1, Decoroso Verrengia1, Kateryna Miedviedieva1, Sciaila Bernardini1, Michele Voglino1, Maurizio Bicchi1, Daniela Merlotti1, Stefania Bisogno1, Pier Leopoldo Capecchi1, Pietro Enea Lazzerini1 | 1Division of Internal Medicine, Electroimmunology Unit, University Hospital of Siena, Italy; 2Division of Rheumatology, University Hospital of Siena, Italy; 3Stroke Unit, University Hospital of Siena, Italy
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PO:14:205 | Primary antiphospholipid antibody syndrome: association between new classification criteria manifestations and a higher-risk disease phenotype Sara Ferrigno1, Vittorio Forte2, Marco Panetta1, Sergio Lisena1, Giorgia Ranucci2, Luigi De Marco1, Elisabetta Greco1, Alberto Bergamini1, Maria Sole Chimenti1, Paola Conigliaro1. | 1Rheumatology, allergology and clinical immunology, Department of Systems Medicine, University of Rome Tor Vergata, Rome, Italy; 2Hematology, Department of Biomedicine and Prevention, University of Rome Tor Vergata, Rome, Italy.
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PO:32:185 | Deep-learning analysis of high-resolution computed tomography images predicts progression and mortality in systemic sclerosis related interstitial lung disease Valentina Boni1, Rosa D'Abronzo2, Piergiacomo Cerasuolo1, Lucio Calandriello2, Giuseppe Cicchetti2, Gerlando Natalello1, Bruno Iovene5, Francesco Varone5, Giacomo Sgalla5, Luca Richeldi5, Anna Rita Larici2|4, Maria Antonietta D'Agostino1|3, Silvia Laura Bosello1|3, Enrico De Lorenzis1. | 1Division of Rheumatology and Clinical Immunology Catholic Univeristy of the Sacred Heart, Rome, Italy; 2Department of Diagnostic Imaging, Oncological Radiotherapy and Hematology, Diagnostic Imaging Area, Catholic University, Rome, Italy; 3Department of Geriatric and Orthopaedic Sciences, Catholic Univeristy of the Sacred Heart, Rome, Italy; 4Department of Radiological and Hematological Sciences, Section of Radiology, Catholic Univeristy of the Sacred Heart, Rome, Italy; 5Division of Pulmonary Medicine, Catholic University of the Sacred Heart, Roma, Italy.
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PO:33:193 | Self-reported oropharyngeal dysphagia and swallowing-related quality of life in people with systemic sclerosis: preliminary results of a cross-sectional study Nikla Pacenti1, Devis Benfaremo2, Federica Lucia Galli2, Andrea Colangelo3, Gianluca Moroncini2 | 1Internal Medicine Residency Program, Marche Polytechnic University Ancona, Italy; 2Department of Clinical and Molecular Sciences, Marche Polytechnic University Ancona, Italy; 3Medical student, Marche Polytechnic University Ancona, Italy
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PO:20:006 | Efficacy of denosumab in glucocorticoid-induced osteoporosis patients with prior exposure to intravenous aminobisphosphonates Kiren Khalid1, Alessandro Giollo1, Mariangela Salvato1, Francesca Frizzera1, Lorenzo Di Luozzo1, Bernd Raffeiner2, Andrea Doria1 | 1Rheumatology Unit, Department of Medicine - DIMED, University of Padova, Padova, Italy; 2Department of Rheumatology, Bolzano Central Hospital, Bolzano, Italy
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PO:06:083 | Clinical characteristics and outcomes of late- and young-onset rheumatoid arthritis in relation to autoantibody status Federica Sabatelli1|2, Ludovico De Stefano1|2, Clelia Zampaglione1|2, Lisa Bergianti1|2, Blerina Xoxi1|2, Antonio Manzo1|2, Carlomaurizio Montecucco1|2, Serena Bugatti1|2. | 1Department of Internal Medicine and Therapeutics, University of Pavia, Pavia; 2Division of Rheumatology, IRCCS Policlinico San Matteo Foundation, Pavia, Italy.
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PO:37:257 | Giant cell arteritis debuting with aortic involvement: the importance of integrated diagnostics in fever of unknown origin Alessandro Gratton1, Giovanni Striani1, Luisa Occhipinti1, Stefania Sacco1, Enrico Pegolo2, Luca Quartuccio1 | 1Rheumatology Clinic and 2 Institute of Anatomical Pathology, Department of Laboratory Medicine, University of Udine, Hospital “Santa Maria della Misericordia”, Udine, Italy
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PO:06:086 | Updated Systematic Literature Review and meta-analysis to Inform the Italian Society of Rheumatology Recommendations on the Treatment of Rheumatoid Arthritis-Associated Interstitial Lung Disease Angelo Fassio1, Marco Sebastiani9|10, Francesco Pollastri1, Chiara Crotti4, Nicola Ughi5, Enrico De Lorenzis6, Silvia Mancuso7, Massimo Radin8, Francesca Cozzini9, Greta Carrara11, Gianpiero Landolfi11, Roberto Rozza11, Andreina Manfredi2|3 | 1Rheumatology Unit, University of Verona, Verona, Italy; 2University of Modena and Reggio Emilia, Reggio Emilia, Italy; 3Rheumatology Unit, AUSL-IRCCS, Reggio Emilia, Italy; 4Bone Disease Unit, Department of Rheumatology and Medical Science, ASST-G.Pini-CTO, Milan, Italy; 5Division of Rheumatology, Multispecialist Medical Department, ASST Grande Ospedale Metropolitano Niguarda, Milano, Italy; 6Department of Aging Diseases, Orthopedic and Rheumatology, Rheumatology Division, P. Gemelli, Roma, Italy; 7Rheumatology Unit, Department of Clinical, Internal, Anaesthesiologic and Cardiovascular, Sciences, Sapienza, Roma, Italy; 8CMID, San Giovanni Bosco Hub Hospital ASL Città di Torino and Department of Clinical and Biological Sciences, Turin, Italy; 9Department of Medicine and Surgery, University of Parma, Parma, Italy; 10Rheumatology Unit, AUSL Piacenza, Piacenza, Italy; 11Unità Epidemiologica, SIR, Società Italiana di Reumatologia, Milano, Italy
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PO:11:175 | Dermatomyositis and immunosuppressant treatment: a case of Staphylococcus aureus pneumonia in a hospitalized patient Simona Fichera1, Andrea Cito1, Martina Vigilia1, Maria Morrone1, Teresa Caferri1, Crescenzio Scioscia1, Simone Perniola1, Giuseppe Lopalco1, Florenzo Iannone1. | 1Unit of Rheumatology, Department of Precision and Regenerative Medicine, Area Jonica, University of Bari, Bari, Italy.
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PO:24:062 | Transcriptomic profile of salivary glands in patients with primary Sjögren’s syndrome and interstitial lung disease: implications for pathogenesis and risk stratification Elisa Pignatti1, Monia Maccaferri1, Alessandra Bisagni2, Alberto Cavazza2, Marco Sebastiani3|4, Luca Keller2, Luca Magnani5, Claudio Galluzzo2, Tommaso Fasano6, Lucia Nota6, Giulia Canu6, Andreina Manfredi1|2, Carlo Salvarani1|2 | 1Dipartimento Chimomo, Università di Modena e Reggio Emilia Modena; 2Struttura Complessa di Reumatologia, Azienda Unità Sanitaria Locale di Reggio Emilia-IRCCS; 3Dipartimento di Medicina e Chirurgia, Università degli Studi di Parma; 4Divisione di Reumatologia, AUSL di Piacenza; 5UOC Medicina Interna ind. reumatologico, AUSL di Bologna, Ospedale Maggiore, Bologna; 6Dipartimento Interaziendale ad Attività Integrata Medicina di Laboratorio ed Anatomia Patologica AUSL di Modena, Italy
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PO:15:220 | Outcomes of extra renal flares in systemic lupus erythematosus: longitudinal analysis of a monocentric cohort Marco Oliva1, Giorgia Capozzo1, Giancarlo Cascarano1, Chiara Cardelli1, Dina Zucchi1, Angela Elia1, Elena Elefante2, Viola Signorini2, Chiara Stagnaro2, Chiara Tani1, Marta Mosca1. | 1Rheumatology Unit, Department of Clinical and Experimental Medicine, University of Pisa, Pisa, Italy; 2Rheumatology Unit, AOUP, Pisa, Italy.
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CO:11:3 | Belimumab for lupus nephritis patients with poor kidney function: a post-hoc analysis of the bliss-ln trial Giacomo Emmi1|2, Ersilia Lucenteforte3, Giorgio Limoncella3, Emanuele Chiara1|2, Marta Calatroni4|5, Gabriella Moroni4|5 | 1Clinical Medicine and Rheumatology Unit, Cattinara University Hospital, Trieste, Italy; 2Department of Medical, Surgical and Health Sciences, University of Trieste, Trieste, Italy; 3Department of Statistics, Informatics and Applications Giuseppe Parenti, University of Florence, Florence, Italy; 4Department of Biomedical Sciences, Humanitas University, Pieve Emanuele, Milan, Italy; 5Nephrology and Dialysis Division, IRCCS Humanitas Research Hospital, Milan, Italy
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PO:01:007 | Modulation of cellular senescence in psoriatic arthritis: exploring the potential impact of b/tsDMARDs treatment on telomere length, mtDNA copy number, and oxidative damage Eneida Cela1, Giada De Benedittis2, Arianna D'Antonio1, Andrea Latini3, Chiara Morgante2, Cinzia Cicacci3, Paola Conigliaro1, Mauro Fatica1, Giulia Mori1, Giuseppe Novelli2, Paola Borgiani2, Maria Sole Chimenti1. | 1Rheumatology, Allergology and Clinical Immunology, Department of System Medicine, University of Rome Tor Vergata, Rome, Italy; 2Department of Biomedicine and Prevention, Section of Genetics, University of Rome Tor Vergata, Rome, Italy; 3UniCamillus Saint Camillus International University of Health Sciences, Rome, Italy.
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PO:06:092 | Early achievement of remission confers better outcomes than low disease activity in both seropositive and seronegative patients with new-onset rheumatoid arthritis Clelia Zampaglione1|2, Ludovico De Stefano1|2, Federica Sabatelli1|2, Alessio D'Isanto1|2, Blerina Xoxi1|2, Antonio Manzo1|2, Carlomaurizio Montecucco1|2, Serena Bugatti1|2. | 1Department of Internal Medicine and Therapeutics, University of Pavia, Pavia; 2Division of Rheumatology, IRCCS Policlinico San Matteo Foundation, Pavia, Italy.
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PO:34:205 | Optical coherence tomography angiography: a window on systemic sclerosis microangiopathy Martina Orlandi1, Tommaso Verdina2, Filippo Santoro1, Alessandra Carobbio3, Amelia Spinella1, Marco De Pinto1, Giorgia Roveta1, Dilia Giuggioli1 | 1Internal Medicine Residency Program, Marche Polytechnic University, Ancona; 2Department of Clinical and Molecular Sciences, Marche Polytechnic University, Ancona; 3Department of Interna, Ancona, Italy
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PO:28:128 | Rheumatic fever: an atypical case Giovanni Italiano1, Melania Coscia1, Arianna Monteforte1 | 1AORN S. Anna e S. Sebastiano Caserta, Italy
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CO:02:1 | Frequency and predictors of disease progression in contemporary seronegative undifferentiated arthritis in a treated-to-target early arthritis clinic Elena Manna1, Ludovico De Stefano1|2, Domenico Sorace1|2, Jacopo Pelizza1|2, Blerina Xoxi1|2, Antonio Manzo1|2, Carlomaurizio Montecucco1|2, Serena Bugatti1|2. | 1Department of Internal Medicine and Therapeutics, University of Pavia; 2Division of Rheumatology, IRCCS Policlinico San Matteo Foundation, Pavia, Italy
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PO:31:174 | Increased frequency of anti-RNA polymerase 3 antibodies in patients with systemic sclerosis and silicone breast implants: a multicentre study from the international European Scleroderma Trials and Research cohort Maria Grazia Lazzaroni1, Yolanda Braun-Moscovici2, Elda Piovani1, Claudia Barison1, Liala Moschetti1, Veronica Batani3, Corrado Campochiaro3, Michal Tomcik4, Francesca Motta5, Maria De Santis5, Petros P. Sfikaki6, Masataka Kuwana7, Brigitte Granel8, Roberta Foti9, Virginia Berlingiero10, Joana Caetano11, Yannick Allanore12, Alexandra Balbir-Gurman2, Marco Matucci Cerinic3, Franco Franceschini1, Paolo Airò1. | 1ASST Spedali Civili of Brescia, University of Brescia, Brescia, Italy; 2Rambam Health Care Campus, Rappaport Faculty of Medicine, Technion-Israeli Institute of Tecnology, Haifa, Israel; 3Vita-Salute San Raffaele University, San Raffaele Hospital, Milano, Italy; 4Institute of Rheumatology, Praga, Czech Republic; 5IRCCS Humanitas Research Hospital; Humanitas University, Milano, Italy; 6Joint Rheumatology Program, Medical School, National Kapodistrian University of Athens Atene GREECE; 7Nippon Medical School Hospital Tokyo Japan; 8Hôpital Nord de Marseille; Aix-Marseille Université Marsiglia France; 9AOU Policlinico G. Rodolico San Marco, Catania, Italy; 10Azienda Ospedaliera Universitaria Senese, Siena, Italy; 11Fernando Fonseca Hospital, Amadora, Portugal; 12Université Paris Cité, Cochin Hospital, Parigi, France.
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PO:05:071 | Impact of age at onset on Spondyloarthritis clinical profile and quality of life: a monocentric cohort analysis Federico Fattorini1, Marco Di Battista1, Lorenzo Esti1, Cosimo Cigolini2, Andrea Delle Sedie2, Marta Mosca1|2, Linda Carli1 | 1Rheumatology Unit, Department of Clinical and Experimental Medicine, University of Pisa, Pisa, Italy; 2Rheumatology Unit, AOUP, Pisa, Italy
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PO:13:188 | Menstrual alterations among women with rheumatoid arthritis: a comparative study across treatment modalities with focus on JAK inhibitors Angelica Napoletano1, Francesca Arezzo2, Marco Fornaro1, Giuseppe Lopalco1, Gennaro Cormio2, Vincenzo Venerito1, Florenzo Iannone1. | 1University of Bari, Rheumatology Unit Department of Precision and Regenerative Medicine, Jonica Area, Bari; 2Gynecologic Oncology, IRCCS Istituto Tumori Giovanni Paolo II, Bari, Italy.
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PO:18:276 | Use of anifrolumab in the treatment of difficult-to-treat manifestations in systemic lupus erythematosus Antonella Grimaldi1, Giuseppe Alessandrini2, Laura Quarta1, Maria Rita Ricciardi1, Daniela Costanza1, Clara Minerba1, Eugenio Quarta1 | 1UOC Reumatologia Verona; 2Specialista Dermatologo in Libera Professione, Italy
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