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https://doi.org/10.4081/reumatismo.2026.2253

Is there still someone laughing at Christopher Columbus?

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Published: 24 April 2026
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Christopher Columbus, reactive arthritis, arthritis, history of medicine, history of rheumatology

Authors

Leonardo Punzi
punzileonardo@gmail.com
Institute for the History of Rheumatology, Venice, Italy.
Alberto Perez-Negrete
Institute for the History of Rheumatology, Venice, Italy.
Marco Amedeo Cimmino
Institute for the History of Rheumatology, Venice, Italy.
Andrea Doria
Institute for the History of Rheumatology, Venice, Italy.
Roberto Gerli
Institute for the History of Rheumatology, Venice, Italy.
Gian Domenico Sebastiani
Institute for the History of Rheumatology, Venice, Italy.
Luigi Sinigaglia
Institute for the History of Rheumatology, Venice, Italy.
Piero Marson
Institute for the History of Rheumatology, Venice, Italy.

Cristopher Columbus’s voyages have undoubtedly changed the history of humankind. Even though already a public figure in his lifetime, several facts concerning Columbus’s life, including his final illness, are still under debate...

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Citations

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Allison DJ. Christopher Columbus: first case of Reiter’s disease in the old world? Lancet 1980; 2: 1309.
Oates JK, Hulse EV. Columbus: was it Reiter’s disease? Lancet 1981; 327: 94-5.
Hoenig LJ. The arthritis of Christopher Columbus. Arch Intern Med 1992; 152: 274-77.
Arnett FC, Merrill C, Albardaner F, Mackowiak PA. A mariner with crippling and bleeding eyes. Am J Med Sci 2006; 332: 123-30.
Martínez-Gonzalez LJ, Martínez-Espin E, Alvarez JC, et al. Surname and Y chromosome in Southern Europe: a case study with Colom/Colombo. Eur J Human Genet 2012; 20: 211-6.
McRae M. DNA reveals surprise twist about Christopher Columbus. Science Alert, 29 January 2025. Available from: https://www.sciencealert.com/dna-reveals-surprise-twist-about-christopher-columbus.

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1.
Is there still someone laughing at Christopher Columbus?. Reumatismo [Internet]. 2026 Apr. 24 [cited 2026 Apr. 25];. Available from: https://www.reumatismo.org/reuma/article/view/2253
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