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CO:02:1 | Frequency and predictors of disease progression in contemporary seronegative undifferentiated arthritis in a treated-to-target early arthritis clinic Elena Manna1, Ludovico De Stefano1|2, Domenico Sorace1|2, Jacopo Pelizza1|2, Blerina Xoxi1|2, Antonio Manzo1|2, Carlomaurizio Montecucco1|2, Serena Bugatti1|2. | 1Department of Internal Medicine and Therapeutics, University of Pavia; 2Division of Rheumatology, IRCCS Policlinico San Matteo Foundation, Pavia, Italy
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CO:07:5 | Enhanced fibroblast signatures in females with early rheumatoid arthritis highlights a potential basis for poorer treatment outcomes Benedetta Monosi1, James Perera2, Alessandra Nerviani2|3, Maria Sole Chimenti1, Felice Rivellese2|3, Costantino Pitzalis2|3|4. | 1Rheumatology, Allergology and Clinical Immunology, Department of Systems Medicine, University of Rome Tor Vergata, Rome, Italy; 2Centre for Experimental Medicine and Rheumatology, William Harvey Research Institute, Queen Mary University of London, London, UK; 3Barts Health NHS Trust and Barts Biomedical Research Centre, National Institute for Health and Care Research, London, UK; 4Department of Biomedical Sciences Humanitas University and IRCCS Humanitas Research Hospital, Milano, Italy
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PO:06:092 | Early achievement of remission confers better outcomes than low disease activity in both seropositive and seronegative patients with new-onset rheumatoid arthritis Clelia Zampaglione1|2, Ludovico De Stefano1|2, Federica Sabatelli1|2, Alessio D'Isanto1|2, Blerina Xoxi1|2, Antonio Manzo1|2, Carlomaurizio Montecucco1|2, Serena Bugatti1|2. | 1Department of Internal Medicine and Therapeutics, University of Pavia, Pavia; 2Division of Rheumatology, IRCCS Policlinico San Matteo Foundation, Pavia, Italy.
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PO:11:171 | Subcutaneous tocilizumab use in a young-onset mixed connective tissue disease patient with multiple treatment failures Rhaysa Araujo Mousinho1, Elide Lupi2, Massimiliano Limonta2 | 1Clinica di Reumatologia, Dipartimento di Medicina and 2Istituto di Anatomia Patologica, Dipartimento di Medicina di Laboratorio, Osp. S. M. della Misericordia, Università di Udine, Italy
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PO:07:099 | Survival on therapy of certolizumab pegol in rheumatoid arthritis, psoriatic arthritis, and spondyloarthritis: 8-year data from an Italian multicenter register Maria Manara1, Gilberto Cincinelli1|2, Marco Fornaro3, Simone Perniola4, Elisa Gremese5, Chiara Bazzani6, Serena Bugatti7, Francesca Romana Spinelli8, Rosario Foti9, Marco Sebastiani10, Alberto Cauli11, Fabiola Atzeni12, Giovanni Lapadula13, Gianfranco Ferraccioli14, Fabrizio Conti8, Florenzo Iannone3, Roberto Caporali1|2 | 1Department of Rheumatology and Medical Sciences, ASST G. Pini-CTO Milano; 2Department of Clinical Sciences and Community Health, University of Milan; 3Department of Precision and Regenerative Medicine and Ionian Area, University of Bari; 4Clinical Immunology Division, Fondazione Policlinico Universitario A. Gemelli IRCCS, Roma; 5Rheumatology and Clinical Immunology, IRCCS Humanitas Research Hospital, Rozzano (MI); 6Unit of Rheumatology and Clinical Immunology, ASST Spedali Civili Brescia; 7Department of Internal Medicine and Therapeutics, Università di Pavia; 8Rheumatology Unit, Dipartimento Scienze Cliniche Internistiche, Anestesiologiche e Cardiovascolari, Sapienza University, Roma; 9Rheumatology Unit, San Marco Hospital, Policlinico University of Catania; 10Rheumatology Unit, AUSL Piacenza, University of Parma; 11UOC di Reumatologia, Dipartimento di Scienze Mediche e Sanità Pubblica, Azienda Ospedaliero-Universitaria di Cagliari; 12Rheumatology Unit, Department of Experimental and Internal Medicine, University of Messina; 13Gruppo Italiano di Studio sulla Early Arthritis, GISEA, Bari; 14Department of Medicine, Università Cattolica del Sacro Cuore, Fondazione IRCCS Policlinico Gemelli, Roma, Italy
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PO:07:101 | Efficacy and safety of methotrexate in a cohort of patients affected by early-onset rheumatoid arthritis: a monocentric real-life study Carlo Cauli1, Martina Favretti2, Giulio Dolcini2, Vincenzo Ferraro1, Cristina Iannuccelli3, Fabrizio Conti1, Manuela Di Franco1 | 1UOC Reumatologia, Dipartimento di scienze cliniche internistiche anestesiologiche e cardiovascolari, Sapienza, Roma; 2Dipartimento di Medicina Molecolare, La Sapienza, Roma; 3UOC Reumatologia, AOU Policlinico Umberto I, La Sapienza, Roma, Italy
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S05:6 | Prevalence of osteoporosis and bone mineral metabolism disorders in an Italian cohort of patients with microcrystalline arthritis: results from the PREMIA observational study of the Italian Society of Rheumatology Silvia Grignaschi1, Sonia Farah2, Silvia Balduzzi1, Bernd Raffeiner3, Carlomaurizio Montecucco4, Fausto Salaffi2, Enrico Selvi5, Annamaria Iagnocco6, Fabiola Atzeni7, Serena Guiducci8, Rosario Foti9, Maria Manara10, Marcello Govoni11, Carlo Selmi12, Francesca Oliviero13, Roberta Ramonda13 | 1ASST Pavia; 2Ospedale Carlo Urbani Jesi Italy; 3Azienda Sanitaria dell'Alto Adige, Bolzano; 4IRCCS Fondazione Policlinico San Matte, Pavia; 5AOU Senese, Siena; 6Ospedale MAuriziano, Torino; 7Università di Messina; 8AOU Careggi, Firenze; 9AOU Policlinico G. Rodolico, Catania; 10ASST Gaetano Pini-CTO Milano; 11AUSL Ferrara; 12Humanitas San Pio X, Milano; 13AOU Padova, Italy
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CO:02:2 | Effectiveness of tumor necrosis factor inhibitors in rheumatoid arthritis: real world data from an Italian National Registry Valerio Fiorilli1, Francesca Romana Spinelli1, Florenzo Iannone2, Chiara Bazzani3, Alberto Cauli4, Rosario Foti5, Marcello Govoni6, Francesco Paolo Cantatore7, Fabiola Atzeni8, Roberto Caporali9, Marco Sebastiani10, Roberta Ramonda11, Serena Bugatti12, Elisa Gremese13, Maria Sole Chimenti14, Bruno Frediani15, Maurizio Rossini16, Angelo Semeraro17, Leonardo Santo18, Gianfranco Ferraccioli19, Giovanni Lapadula20, Fabrizio Conti1. | 1Dipartimento di Scienze Cliniche Internistiche, Anestesiologiche e Cardiovascolari, Sapienza Università di Roma; 2Dipartimento di Medicina di Precisione e Rigenerativa e Area Jonica, Università degli Studi Aldo Moro, Bari; 3ASST Spedali Civili di Brescia, Unità di Reumatologia ed Immunologia Clinica, Brescia; 4Dipartimento di Scienze Mediche e Sanità Pubblica, Università degli Studi di Cagliari; 5A.O.U. Policlinico S. Marco, UOS Reumatologia, Catania; 6Dipartimento di Scienze Mediche, Università di Ferrara; 7Unità di Reumatologia, Dipartimento di Medicina Specialistica, Università di Foggia; 8Dipartimento di Medicina Interna e Terapia Medica, UOC di Reumatologia, Università di Messina; 9Dipartimento di Scienze Cliniche e di Comunità, Università di Milano; 10Dipartimento di Medicina e Chirurgia, Università di Parma; 11Unità di Reumatologia, Dipartimento di Medicina, Università di Padova; 12Dipartimento di Medicina Interna e Terapia Medica, Università di Pavia, ; 13IRCCS Istituto Clinico Humanitas, Dipartimento di Scienze Biomediche, Milano; 14Dipartimento di Medicina dei Sistemi, Università degli Studi di Roma-Tor Vergata, ; 15Dipartimento di Medicina Clinica e Scienze Immunologiche, Università di Siena; 16Dipartimento di Medicina, Università di Verona; 17Presidio Ospedaliero Valle d'Itria, Unità Operativa di Reumatologia, Martina Franca; 18Presidio Ospedaliero "Mons. Dimiccoli", Unità Operativa Semplice di Reumatologia, Barletta; 19Gruppo Italiano di Studio sulla Early Arthritis, GISEA, Roma; 20Gruppo Italiano di Studio sulla early Arthritis, GISEA, Bari, Italy.
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PO:10:155 | Etanercept-induced lupus in a patient with rheumatoid arthritis: diagnostic challenges and multidisciplinary therapeutic approach Camilla Riboldi1|2, Claudia Iannone1|2, Maria Gerosa1|2, Roberto Felice Caporali1|2 | 1ASST G. Pini-CTO, U.O.C. di Clinica Reumatologica, Milano; 2Dipartimento di Scienze Cliniche e di Comunità, Università degli Studi di Milano, Italy
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PO:07:107 | Performance of the 2010 ACR/EULAR classification criteria for Rheumatoid Arthritis in a group of elderly onset patients Alessandra Rai1, Pierluigi Macchioni1, Giovanni Barausse2, Luigi Boiardi1, Giuseppe Paolazzi2, Carlo Salvarani1, Andreina Manfredi1 | 1University of Modena and Reggio Emilia, USL-IRCCS Reggio Emilia, Italy; 2Rheumatology Unit, Ospedale di Trento, Italy
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PO:07:111 | Worsening of patient-reported outcomes is an early predictor of disease flare in patients with rheumatoid arthritis in course of treatment with conventional synthetic disease modifying anti-rheumatic drugs Ludovico De Stefano1|2, Federica Sabatelli1|2, Clelia Zampaglione1|2, Blerina Xoxi2, Antonio Manzo1|2, Carlomaurizio Montecucco1|2, Serena Bugatti1|2. | 1Department of Internal Medicine and Therapeutics, University of Pavia, Pavia, Italy; 2Division of Rheumatology, IRCCS Policlinico San Matteo Foundation, Pavia, Italy.
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PO:26:096 | From free text to diagnosis: a Natural Language Processing approach for identifying rheumatoid and psoriatic arthritis in the Emergency Department Antonio Tonutti1|2, Pierandrea Morandini3, Cosimo Faeti3, Nicoletta Luciano1|2, Saverio D'Amico3, Antonio Voza1|4, Victor Savevski3, Carlo Selmi1|2 | 1Department of Biomedical Sciences, Humanitas University Pieve Emanuele, Milan, Italy; 2Rheumatology and Clinical Immunology, IRCCS Humanitas Research Hospital Rozzano, Milan, Italy; 3Artificial Intelligence Unit, IRCCS Humanitas Research Hospital Rozzano, Milan, Italy; 4Emergency Department, IRCCS Humanitas Research Hospital Rozzano, Milan, Italy
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PO:01:003 | Sex-based differences in 2 years treatment outcomes with b/ts-DMARDs in psoriatic arthritis: from real-world evidence to predictive modeling from the Gruppo Italiano Studio Early Arthritis (GISEA) prospective registry Simone Perniola1, Florenzo Iannone1, Francesco Paolo Cantatore2, Angelo Semeraro3, Leonardo Santo4, Roberto Gorla5, Alberto Cauli6, Roberto Felice Caporali7, Bruno Frediani8, Rosario Foti9, Fabrizio Conti10, Marco Sebastiani11, Maria Sole Chimenti12, Roberta Ramonda13, Fabiola Atzeni14, Maurizio Rossini15, Serena Bugatti16, Serena Guiducci17, Giovanni Lapadula1, Gianfranco Ferraccioli18, Francesca Romana Spinelli10, Elisa Gremese19. | 1Rheumatology Unit, DiMePReJ, University of Bari, Bari; 2Rheumatology Unit, Department of Medical and Surgical Sciences, Azienda Ospedaliero-Universitaria Policlinico Riuniti, Foggia; 3Rheumatology Unit, Martina Franca Hospital; 4Rheumatology Unit, ASL BT, P.O. Barletta; 5Rheumatology and Clinical Immunology Unit, ASST Spedali Civili of Brescia; 6Rheumatology Unit, Department of Medical Science and Public Health, University of Cagliari, Monserrato (CA); 7Rheumatology Unit, Dipartimento di Reumatologia e Scienze Mediche, ASST PINI-CTO, University of Milano, Milano; 8Rheumatology Unit, Azienda Ospedaliero Universitaria Senese, Siena; 9Rheumatology Unit, A.O.U. Policlinico S. Marco, Catania; 10Rheumatology Unit, Department of Clinical Internal, Anesthesiologic and CV Sciences, Sapienza University of Rome, Roma; 11Rheumatology Unit, AUSL Piacenza, University of Parma, Parma; 12Rheumatology, Department of Systems Medicine, University of Rome Tor Vergata, Roma; 13Rheumatology Unit, DIMED, University of Padua, Padova; 14Rheumatology Unit, Department of Experimental and Internal Medicine, University of Messina, Messina; 15Rheumatology Unit, Department of Medicine, University of Verona, Verona; 16Division of Rheumatology, Dept. of Internal Medicine and Therapy, Fondazione IRCCS Policlinico S. Matteo, University of Pavia, Pavia; 17Division of Rheumatology, Department of Experimental and Clinical Medicine, University of Firenze, Firenze; 18Department of Medicine, Catholic University of the Sacred Heart, Fondazione Policlinico Gemelli IRCCS, Roma; 19Rheumatology and Clinical Immunology, IRCCS Humanitas Research Hospital, Humanitas University, Rozzano (MI), Italy
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PO:12:184 | Atrioventricular conduction in chronic inflammatory arthritis: enhanced assessment by new electrocardiographic parameters Riccardo Accioli1, Viola Salvini1, Anna Cantore1, Fabio Salvadori1, Enrico Selvi2, Virgina Berlengiero2, Maurizio Acampa3, Alessandra Cartocci1, Kateryna Miedviedieva1, Decoroso Verrengia1, Sciaila Bernardini1, Michele Voglino1, Giovanni Donati1, Silvia Petri1, Severino Gallo1, Stefania Bisogno1, Pier Leopoldo Capecchi1, Pietro Enea Lazzerini1 | 1Division of Internal Medicine, Electroimmunology Unit, University Hospital of Siena, Italy; 2Division of Rheumatology, University Hospital of Siena, Italy; 3Stroke Unit, University Hospital of Siena, Italy
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PO:04:046 | Achieving Early Clinical Response was Associated with Cumulative Benefits on Disease Impact up to 2 Years in Patients with Active Psoriatic Arthritis Treated with Bimekizumab William Tillett1|2, Joseph F Merola3, Iain B Mcinnes4, Kenneth B Gordon5, Richard B Warren6, Patrick Healy7, Jérémy Lambert8, Heather Edens9, Barbara Ink10, Paola Volpe11, Laure Gossec12 | 1Royal National Hospital of Rheumatic Diseases Bath, United Kingdom; 2Department of Life Sciences, Centre for Therapeutic Innovation, University of Bath Bath, United Kingdom; 3Department of Dermatology and Department of Medicine, Division of Rheumatology, Utah Southwestern Medical Center Dallas, USA; 4College of Medical Veterinary and Life Sciences, University of Glasgow Glasgow, United Kingdom; 5Department of Dermatology, Medical College of Wisconsin Milwaukee, USA; 6Northern Care Alliance, NHS Foundation Trust and Manchester Academic Health Science Centre, University of Manchester Manchester, United Kingdom; 7UCB Morrisville, USA; 8UCB Colombes, France; 9UCB Smyrna, USA; 10UCB Slough, United Kingdom; 11UOC Reumatologia, P.O. Spirito Santo Pescara, Italy; 12Sorbonne Universite and Pitie-Salpetriere Hospital Paris, France
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PO:05:071 | Impact of age at onset on Spondyloarthritis clinical profile and quality of life: a monocentric cohort analysis Federico Fattorini1, Marco Di Battista1, Lorenzo Esti1, Cosimo Cigolini2, Andrea Delle Sedie2, Marta Mosca1|2, Linda Carli1 | 1Rheumatology Unit, Department of Clinical and Experimental Medicine, University of Pisa, Pisa, Italy; 2Rheumatology Unit, AOUP, Pisa, Italy
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PO:08:113 | Shaping rheumatoid arthritis treatment: clinical and demographic drivers of tsDMARDs versus bDMARDs prescription post-EMA pronouncement on JAK inhibitors - insights from the AMBI-RA study Riccardo Bertola1, Beatrice Maranini1, Carlo Garaffoni1, Maria Pozzuto1, Anna Laura Riva Cambrino1, Alessandro Spinelli1, Letizia Mamprin1, Federico Agostini1, Martina Di Nunzio1, Marcello Govoni1, Alessandra Bortoluzzi1, Ettore Silvagni1 | 1Rheumatology Unit, Department of Medical Sciences, University of Ferrara and Azienda Ospedaliero-Universitaria S. Anna, Italy
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PO:22:032 | Beyond the joints: a rare case of subcorneal pustular dermatosis in Rheumatoid Arthritis Sara Casella1|2, Carlo Smirne1|2, Roberta Zaira Pedrazzoli3, Mattia Perazzi1|3, Edoardo Cammarata4, Francesca Zottarelli4, Paola Savoia5, Renzo Boldorini6, Mario Pirisi1|2, Pier Paolo Sainaghi1|3 | 1Dipartimento di Medicina Traslazionale, Università del Piemonte Orientale Novara, Italy; 2Unità di Medicina Interna, Azienda Ospedaliera Maggiore della Carità Novara, Italy; 3Unità di Medicina Interna e Reumatologia, Azienda Ospedaliera Maggiore della Carità Novara, Italy; 4Unità di Dermatologia, Azienda Ospedaliera Maggiore della Carità Novara, Italy; 5Dipartimento di Scienze della salute, Università del Piemonte Orientale Novara, Italy; 6Unità di Anatomia Patologica, Azienda Ospedaliera Maggiore della Carità Novara, Italy
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PO:06:083 | Clinical characteristics and outcomes of late- and young-onset rheumatoid arthritis in relation to autoantibody status Federica Sabatelli1|2, Ludovico De Stefano1|2, Clelia Zampaglione1|2, Lisa Bergianti1|2, Blerina Xoxi1|2, Antonio Manzo1|2, Carlomaurizio Montecucco1|2, Serena Bugatti1|2. | 1Department of Internal Medicine and Therapeutics, University of Pavia, Pavia; 2Division of Rheumatology, IRCCS Policlinico San Matteo Foundation, Pavia, Italy.
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