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PO:35:219 | Real-world effectiveness of mepolizumab on gastrointestinal involvement in eosinophilic granulomatosis with polyangiitis and hypereosinophilic syndrome: a multicentre retrospective study Alessia Gatti1, Francesca Regola1, Giulia Fontana1, Mario Addrea Piga2, Gianluca Moroncini2, Palma Carlucci3, Angelo Vacca3, Paolo Delvino4, Enrico Heffler5, Emanuele Nappi5, Jakub Moll6, Laura Losappio6, Jan Schroeder6, Federica Davanzo7, Roberto Padoan7, Edoardo Conticini8, Paolo Cameli8, Greta Pacini9, Alvise Berti9, Lorenzo Vrola10, Paola Tomietto10, Luca Quartuccio11, Jan Willem Cohen Tervaert12, Sabrina Arnold13, Peter Lamprecht13, Florence Roufosse14, Ilaria Cavazzana1, Franco Franceschini1, Giacomo Emmi15, Paola Toniati1. | 1Rheumatology and Clinical Immunology Unit, ERN ReCONNET, ASST Spedali Civili of Brescia and University of Brescia, Italy, Brescia, Italy; 2Università Politecnica delle Marche and Azienda Ospedaliero Universitaria delle Marche, Ancona, Italy, Ancona, Italy; 3Section of Internal Medicine 'Guido Baccelli', DiMePRe-J, University of Bari 'Aldo Moro', Bari, Italy, Bari, Italy; 4Rheumatology Unit, IRCCS San Gerardo dei Tintori, Monza, Italy Monza Italy; 5Department of Biomedical Sciences, Humanitas University and Personalized Medicine, Asthma and Allergy IRCCS Humanitas, Milano, Italy; 6Division of Allergy and Clinical Immunology, ASST GOM Niguarda, Milan, Italy, Milano, Italy; 7Rheumatology Unit, Department of Medicine DIMED, University of Padua, Padova, Italy, Padova, Italy; 8University of Siena, Siena, Italy, Siena, Italy; 9Santa Chiara Hospital and University of Trento, Unit of Rheumatology, Trento, Italy Trento Italy; 10UCO Medicina Clinica, ASUGI, Cattinara Teaching Hospital, Trieste, Italy, Trieste, Italy; 11Division of Rheumatology, Department of Medicine DMED, University of Udine, Udine, Italy, Udine, Italy; 12University of Alberta, Edmonton, Alberta, Canada and Maastricht University, Maastricht, The Netherlands Maastricht The Netherlands; 13Department of Rheumatology and Clinical Immunology, University of Lübeck, Lübeck, Germany Lubeck Germany; 14Department of Internal Medicine, Hôpital Universitaire de Bruxelles - Erasme, Université Libre de Bruxelles, Belgium Brussels Belgium; 15Clinical Medicine and Clinical Immunology and Rheumatology Unit Cattinara University Hospital and University of Trieste, Trieste, Italy.
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PO:01:004 | Real-world retention of IL-17 inhibitors in psoriatic arthritis: impact of prior IL-17 exposure across multiple treatment lines in the “BIRRA” multicentre cohort Valentino Paci1, Alarico Ariani2, Eleonora Celletti3, Alberto Lo Gullo4, Camilla Mazzanti5, Valeria Nucera6, Natalia Mansueto7, Rosalba Caccavale8, Patrizia Del Medico9, Antonella Farina10, Palma Scolieri11, Cecilia Giampietro12, Olga Addimanda13, Riccardo Bixio14, Maddalena Larosa15, Viviana Ravagnani16, Federica Lumetti17, Aldo Biagio Molica Colella17, Elena Bravi17, Rosetta Vitetta17, Bernd Raffeiner17, Gilda Sandri18, Rosario Foti19, Simone Parisi20, Michele Maria Luchetti Gentiloni1, Gianluca Moroncini1. | 1Clinical Medicine, Department of Clinical and Molecular Sciences, Marche Polytechnic University, AOU delle Marche, Ancona, Italy; 2Internal Medicine and Rheumatology Unit, University Hospital of Parma, Parma, Italy; 3Rheumatology Unit, Clinica Medica Institute, Ospedale SS. Annunziata di Chieti, G.d'Annunzio University of Chieti, Chieti, Italy; 4Rheumatology Unit, ARNAS Garibaldi di Catania, Catania, Italy; 5Center for the Diagnosis and Therapy of Autoimmune Rheumagological Diseases, Ospedale Santa Rosa, ASL Viterbo Viterbo Italy; 6Rheumatology Outpatient Unit, ASL Novara, Novara, Italy; 7Ambulatori di Reumatologia ASL1 Liguria, Imperia Hospitall Imperia Italy; 8Department of Clinical, Anesthesiological and Cardiovascular Sciences, Sapienza University of Rome, Polo Pontino, Roma, Italy; 9Rheumatology outpatient clinic - Internal Medicine Unit, Civitanova Marche Hospital, Civitanova Marche, Italy; 10Internal Medicine Unit, Rheumatology outpatient clinic, Ospedale A. Murri di Fermo, Fermo, Italy; 11Department of Medical Specialties, Nuovo Regina Margherita Hospital, Rome, Roma, Italy; 12Rheumatology Outpatient Clinic, Azienda ULSS 6 Euganea, Padova, Padova, Italy; 13Rheumatology Unit, Azienda Unità Sanitaria Locale di Bologna -- Policlinico S.Orsola- AOU di Bologna, Bologna, Italy; 14Rheumatology Unit, IRCCS Sacro Cuore Don Calabria Hospital, Negrar di Valpolicella, Verona, Italy; 15Division of Rheumatology - Medical Specialties Department, Ospedale La Colletta-Azienda Sanitaria Locale 3, Genova, Italy; 16Rheumatology Unit, Santa Chiara Hospital APSS Trento Italy; 17BIRRA - BIologic Retention Rate in chronic Arthritis - study group, Parma, Italy; 18Rheumatology Unit, University of Modena and Reggio Emilia, Modena, Italy; 19Rheumatology Unit, Policlinico San Marco Hospital, Catania, Italy; 20Rheumatology Department, Azienda Ospedaliera Universitaria Città della Salute e della Scienza di Torino, Torino, Italy.
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PO:06:079 | Weighing the burden: how body mass index shapes clinical outcomes in rheumatoid arthritis. Insights from a large Italian cohort Marco Capodiferro1, Marco Fornaro1, Gian Luca Erre2, Matteo Piga3, Elena Bartoloni Bocci4, Andreina Manfredi5, Ennio Giulio Favalli6, Maria Sole Chimenti7, Serena Guiducci8, Eleonora Celletti9, Addolorata Corrado10, Alessandro Giollo11, Simone Parisi12, Ivan Giovannini13, Elisa Gremese14, Garifallia Sakellariou15, Ombretta Viapiana16, Fabiola Atzeni17, Francesca Romana Spinelli18, Fabio Cacciapaglia1|19. | 1Rheumatology Unit, Department of Precision and Regenerative Medicine and Ionian Area DiMePRe-J University of Bari, Bari, Italy; 2Dipartimento di Scienze Mediche, Chirurgiche e Sperimentali, Università degli Studi di Sassari, Sassari, Italy; 3Rheumatology Unit, AOU Cagliari, Department of Medical Sciences and Public Health, University of Cagliari, Cagliari, Italy; 4Rheumatology Unit, Department of Medicine and Surgery, University of Perugia, Perugia, Italy; 5Rheumatology Unit, Azienda Ospedaliera Universitaria Policlinico of Modena, Modena, Italy; 6Dpt of Rheumatology, G. Pini Institute, Milano, Italy; 7Rheumatology, Allergology and Clinical Immunology, Department of Systems Medicine, University of Rome Tor Vergata, Rome, Italy; 8Department of Experimental and Clinical Medicine, Division of Rheumatology, University of Florence, Firenze, Italy; 9Rheumatology Unit, SS Annunziata Hospital, Chieti, Italy; 10Rheumatology Unit, Department of Medical and Surgical Sciences, University of Foggia, Foggia, Italy; 11Rheumatology Unit, Department of Medicine, University of Padova Hospital Trust, Padova, Italy; 12Rheumatology Department, A.O.U. Città della Salute e della Scienza, Torino, Italy; 13Rheumatology Department, Santa Maria della Misericordia Hospital, Udine, Italy; 14Rheumatology and Clinical Immunology, IRCCS Humanitas Research Hospital, Rozzano (MI), Italy; 15Department of Internal Medicine and Therapeutics, University of Pavia, Istituti Clinici Scientifici Maugeri, Pavia, Italy; 16Rheumatology Unit, Department of Medicine, University and Azienda Ospedaliera Universitaria Integrata of Verona, Verona, Italy; 17Rheumatology Unit, Department of Experimental and Internal Medicine, University of Messina, Messina, Italy; 18Reumatology Unit, Department of Internal, Anesthesiological, and Cardiovascular Clinical Sciences, Sapienza University, Roma, Italy; 19Miulli General Hospital Acquaviva - Department of Medicine and Surgery, LUM F. De Gennaro University, Casamassima (BA), Acquaviva delle Fonti (BA), Italy.
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PO:02:016 | Real-world evidence of upadacitinib over two years in Italian patients with axial spondyloarthritis Mariagrazia Lorenzin1, Giacomo Cozzi1, Stefano Gentileschi2, Michele Maria Luchetti Gentiloni3, Antonio Carletto4, Maria Sole Chimenti5, Maria Manara6, Luca Quartuccio7, Rosario Foti8, Salvatore D'Angelo9, Ariela Hoxha10, Carlo Selmi11, Bernd Raffeiner12, Alessandro Giollo1, Alberto Cauli13, Carlo Salvarani14, Fabiola Atzeni15, Roberta Ramonda1, Sir Study Group Spa E Psa Antonio Spadaro16. | 1Rheumatology Unit, Department of Medicine DIMED, University of Padova, Padova, Italy; 2Rheumatology Unit, Department of Medicine, Surgery and Neurosciences, University of Siena, Siena, Italy; 3Clinica Medica, Ospedali Riuniti Ancona University Hospital, Ancona; Department of Clinical and Molecular Sciences, Ancona, Italy; 4Rheumatology Unit, Department of Medicine, AOUI University of Verona, Verona, Italy; 5Rheumatology, allergology and clinical Immunology, Department of Systems Medicine, University of Rome Tor Vergata, Roma, Italy; 6Humanitas San Pio X, Milano, Italy; 7University of Udine, Academic Hospital Santa Maria della Misericordia, Udine, Italy; 8Rheumatology Unit, A.O.U. Policlinico S. Marco, Catania, Italy; 9Rheumatology Department of Lucania, San Carlo Hospital of Potenza and Madonna delle Grazie Hospital of Matera, Potenza, Italy; 10Internal Medicine Unit, Thrombotic and Hemorrhagic Center, Department of Medicine-DIMED, University of Padua, Padova, Italy; 11Department of Rheumatology and Clinical Immunology, IRCCS Humanitas Research Hospital, Rozzano, Milano, Italy; 12Department of Rheumatology, Teaching Hospital of the Paracelsius Medical Hospital of Bolzano ASAA-SABES, Bolzano, Italy; 13Rheumatology Unit, Department of Medical Sciences, AOU and University of Cagliari, Monserrato, Cagliari, Italy; 14Department of Rheumatology, Azienda USL-IRCCS di Reggio Emilia and Università di Modena and Reggio Emilia, Reggio Emilia, Italy; 15Rheumatology Unit, University of Messina, Messina, Italy; 16Società Italiana di Reumatologia, Milano, Italy.
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PO:06:084 | Interstitial lung involvement in rheumatoid arthritis patients treated with abatacept: a prospective observational study Francesca Cozzini1|2, Andreina Manfredi2|3, Antonio Carletto4, Elisa Bellis5, Laura Cometi6, Vincenzo Venerito7, Caterina Vacchi8, Fabiola Atzeni9, Antonio Carriero10, Rosaria Foti11, Mariagrazia Catanoso3, Ennio Favalli12, Chiara Bazzani13, Arianna Belvedere3, Cecilia Burattini1, Andrea Morciano4, Annamaria Iagnocco5, Gemma Lepri6, Florenzo Iannone7, Antonio Pezzano9, Salvatore D'Angelo10, Valentina Cateni4, Serena Guiducci6, Marco Sebastiani1|14. | 1Ospedale Guglielmo da Saliceto, Piacenza, Italy; 2Università degli studi di Modena e Reggio Emilia, Modena, Italy; 3IRCCS Arcispedale Santa Maria Nuova, Reggio Emilia, Italy; 4AOUI, Università degli studi di Verona, Verona, Italy; 5A.O. Mauriziano di Torino, Università degli studi di Torino, Torino, Italy; 6AOU di Careggi, Università degli studi di Firenze, Firenze, Italy; 7AOU Policlinico di Bari, università degli studi di Bari Aldo Moro, Bari, Italy; 8AOU Policlinico di Modena, Modena, Italy; 9AOU Gaetano Martino, Università degli studi di Messina, Messina, Italy; 10Azienda Ospedaliera Regionale San Carlo, Potenza, Italy; 11AO Vittorio Emanuele, Catania, Italy; 12ASST Gaetano Pini, Milano, Italy; 13ASST Spedali Civili, Brescia, Italy; 14Università degli studi di Parma, Parma, Italy.
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PO:31:172 | Age and timing of onset of Raynaud's phenomenon and first non-Raynaud sign/symptom as prognostic factors in systemic sclerosis: a retrospective analysis from the systemic sclerosis progression investigation registry of the Italian Society for Rheumatology Silvia Peretti1, Cosimo Bruni2, Silvia Laura Bosello3, Fabio Cacciapaglia4-5, Corrado Campochiaro6-7, Veronica Codullo8, Lorenzo Dagna6-7, Rossella De Angelis9, Giacomo De Luca6-7, Dilia Giuggioli10, Serena Guiducci1, Florenzo Iannone4, Francesca Ingegnoli11, Valeria Riccieri12, Marco Matucci Cerinic6-7, Clodoveo Ferri10-13, Silvia Bellando Randone1. | 1Division of Rheumatology, Scleroderma Unit, Department of Experimental and Clinical Medicine, University of Florence, AO, Firenze, Italy; 2Division of Rheumatology, University Hospital Zurich, University of Zurich, Zurich, Switzerland; 3Rheumatology Division, Catholic University of the Sacred Heart, Fondazione Policlinico Universitario A. Gemelli- IRCCS, Roma, Italy; 4Rheumatology Unit, Department of Precision and Regenerative Medicine-Ionian Area, University of Bari Aldo Moro, Bari, Italy; 5Reumatology Service, Internal Medicine Unit F.Miulli General Hospital, Acquaviva delle Fonti -Department of Medicine a, Bari, Italy; 6Unit of Immunology, Rheumatology, Allergy and Rare Diseases UnIRAR, Inflammation, Fibrosis and Ageing initiative INFL, Milano, Italy; 7Vita-Salute San Raffaele University, Milano, Italy; 8Department of Internal Medicine and Therapeutics, Università di Pavia, Italy; Division of Rheumatology, Fondazione IRCCS, Pavia, Italy; 9Rheumatology Unit, Department of Clinical and Molecular Sciences, Polytechnic University of Marche, Ancona, Italy; 10Rheumatology Unit, School of Medicine, University of Modena and Reggio Emilia, Modena, Italy; 11Division of Clinical Rheumatology, ASST Pini, Dept. of Clinical Sciences and Community Health, Research Center for Adul, Milano, Italy; 12Department of Rheumatology, Sapienza University of Rome, Roma, Italy; 13Rheumatology Clinic Madonna dello Scoglio Crotonei, Crotone, Italy.
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PO:20:003 | Romosozumab effect on neutrophil-to-lymphocyte ratio in post-menopausal women at high risk of fracture Giorgia Scagliosi1, Mariana Diaz Lopez1, Martina Teoni1, Francesco Pollastri1, Anna Piccinelli1, Camilla Benini1, Valeria Messina1, Emma Pasetto1, Davide Gatti1, Ombretta Viapiana1, Maurizio Rossini1, Giovanni Adami1. | 1Università di Verona, Dipartimento di Medicina, Verona, Italy; 2Università di Verona, Dipartimento di Medicina, Verona, Italy; 3Università di Verona, Dipartimento di Medicina, Verona, Italy; 4Università di Verona, Dipartimento di Medicina, Verona, Italy; 5Università di Verona, Dipartimento di Medicina, Verona, Italy; 6Università di Verona, Dipartimento di Medicina, Verona, Italy; 7Università di Verona, Dipartimento di Medicina, Verona, Italy; 8Università di Verona, Dipartimento di Medicina, Verona, Italy; 9Università di Verona, Dipartimento di Medicina, Verona, Italy; 10Università di Verona, Dipartimento di Medicina, Verona, Italy; 11Università di Verona, Dipartimento di Medicina, Verona, Italy; 12Università di Verona, Dipartimento di Medicina, Verona, Italy.
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PO:15:222 | Post-hoc analysis of the BeRLiSS-JS registry: efficacy of belimumab on thrombocytopenia Greta Hulej1, Margherita Zen1, Marisol Bracalenti1, Francesca Bottazzi2, Rossella De Angelis3, Giacomo Emmi4, Roberto Gerli5, Marcello Govoni6, Renato Lo Gullo7, Simone Negrini8, Luca Quartuccio9, Maurizio Rossini10, Carlo Salvarani11, Paola Tomietto4, Angelo Vacca12, Andrea Doria1, Luca Iaccarino1. | 1Università degli Studi di Padova, Padova, Italy; 2Università degli Studi di Pavia, Pavia, Italy; 3Università Politecnica delle Marche, Ancona, Italy; 4Università degli Studi di Trieste, Trieste, Italy; 5Università degli Studi Perugia, Perugia, Italy; 6Università degli Studi di Ferrara, Ferrara, Italy; 7Università degli Studi di Catania, Catania, Italy; 8Università degli Studi di Torino, Torino, Italy; 9Università degli Studi di Udine, Udine, Italy; 10Università degli Studi di Verona, Verona, Italy; 11Università degli Studi di Modena e Reggio Emilia, Modena, Italy; 12Università degli Studi di Bari .
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PO:31:175 | Characterizing gastrointestinal involvement in systemic sclerosis: insights from the national systemic sclerosis progression investigation registry of the Italian Society of Rheumatology Francesco Bonomi1, Cosimo Bruni1|2, Silvia Laura Bosello3, Fabio Cacciapaglia4|5, Corrado Campochiaro6, Roberto Caporali7, Veronica Codullo8, Maria Antonietta D'Agostino3, Lorenzo Dagna6, Rossella De Angelis9, Giacomo De Luca6, Dilia Giuggioli10, Serena Guiducci1, Florenzo Iannone4, Francesca Ingegnoli7, Carlomaurizio Montecucco8, Valeria Riccieri11, Clodoveo Ferri10, Marco Matucci Cerinic6, Silvia Bellando Randone1. | 1Scleroderma Unit, Division of Rheumatology AOUC, and Department of Experimental and Clinical Medicine, Uni. of Florence, Firenze, Italy; 2Department of Rheumatology, University Hospital Zurich, University of Zurich Zurigo Switzerland; 3UOC of Rheumatology and Clinical Immunology, Catholic University of the Sacred Heart, Fondazione Policlinico A. Gemelli, Roma, Italy; 4Rheumatology Unit, Department of Emergency Surgery and Organ Transplantations, University of Bari, Bari, Italy; 5Rheumatology Service, F. Miulli General Hospital - Department of Medicine and Surgery, LUM 'G. De Gennaro', Casamassima, Italy; 6Unit of Immunology, Rheumatology, Allergy and Rare Diseases and Inflammation, fibrosis and ageing initiative, UniSR, Milano, Italy; 7Division of Clinical Rheumatology, ASST Pini and Università degli studi di Milano, Milano, Italy; 8Department of Rheumatology, Policlinico San Matteo, Pavia, Italy; 9Rheumatology Unit, Department of Clinical and Molecular Sciences, Polytechnic University of Marche, Ancona, Italy; 10Rheumatology Unit, School of Medicine, University of Modena and Reggio Emilia, Modena, Italy; 11Department of Rheumatology, Sapienza University of Rome, Roma, Italy.
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PO:08:126 | Use of upadacitinib in real-life: the experience of Calabrian rheumatology Vincenzo Raimondo1, Maurizio Caminiti2, Pietro Gigliotti3, Giuseppe Varcasia4, Massimo L'Andolina5, Domenico Olivo6, Roberta Pellegrini7, Pietro Muto8, Marilena Calabria9, Laura Massaro10, Jessica Maria El Luppino11, Salvatore De Bonis12, Giuseppa Pagano Mariano2, Stefania Sorbara3, Virginia Caira4, Mariateresa Cirillo5, Caterina Bruno9, Clodoveo Ferri11 | 1UOC di Reumatologia, Dipartimento SCIAC, Sapienza Università di Roma; 2Dipartimento di Medicina, Clinica di Reumatologia, Università degli Studi di Udine; 3UOC Medicina Interna e Nefrologia, Dipartimento MeSVA, Università degli Studi di L'Aquila; 4UniCamillus, San Camillo Università Internazionale di Scienze della Salute di Roma, Italy; 5Ambulatorio di Reumatologia, Ospedale di Tropea, Tropea, Italy; 6ASP Crotone, Ambulatorio di Reumatologia, Crotone, Italy; 7Ambulatorio di Reumatologia, Ospedale Annunziata di Cosenza, Cosenza, Italy; 8Ambulatorio di Reumatologia, Ospedale di Paola, Paola, Italy; 9Ambulatorio di Reumatologia, SOC di Medicina Interna, AOU Dulbecco, Catanzaro, Italy; 10Ambulatorio di Reumatologia, Ospedale di Praia a Mare, Praia a Mare, Italy; 11Casa di Cura Madonna dello Scoglio, Reparto di Reumatologia, Cotronei, Italy - Affiliazione 12: Ambulatorio di Reumatologia, ospedale di Acri, Acri, Italy
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PO:33:190 | Travel distance to tertiary healthcare reflects disease severity and medication access in systemic sclerosis patients: insights from the Italian systemic sclerosis progression investigation registry of the Italian Society of Rheumatology Camilla Teresa Magnanimi1, Enrico De Lorenzis1, Gerlando Natalello1, Fabio Cacciapaglia2, Rossella De Angelis3, Edoardo Cipolletta3, Maria Antonietta D'Agostino1, Veronica Cudullo4, Giacomo De Luca5, Dilia Giuggioli6, Francesca Ingegnoli7, Valeria Riccieri8, Lorenzo Dagna5, Fiorenzo Iannone9, Clodoveo Ferri6, Marco Matucci Cerinic5, Silvia Laura Bosello1. | 1Division of Rheumatology and Clinical Immunology, Catholic University of the Sacred Heart, Fondazione Policlinico Univer, Roma, Italy; 2Department of Medicine and Surgery, LUM University Giuseppe De Gennaro Casamassima e Rheumatology Service Miulli Ge, Bari, Italy; 3Rheumatology Unit - Department of Clinical and Molecular Sciences, Polytechnic University of Marche, Ancona, Italy; 4Department of Rheumatology, Policlinico San Matteo, Pavia, Italy; 5Unit of Immunology, Rheumatology, Allergy and Rare Diseases UnIRAR, IRCCS San Raffaele Scientific Institute, Vita-Salu, Milano, Italy; 6Rheumatology Unit, School of Medicine, University of Modena and Reggio Emilia, Modena, Italy; 7Division of Clinical Rheumatology, ASST Pini, Dept. of Clinical Sciences e Community Health, Research Center for Adult a, Milano, Italy; 8Department of Rheumatology, La Sapienza University of Rome, Roma, Italy; 9Rheumatology Unit, Department of Precision and Regenerative Medicine and Ionian Area, University of Bari, Bari, Italy.
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PO:25:081 | Atypical onset of anti-SAE-1 positive dermatomyositis: paraneoplastic flame hemorrhages in urothelial carcinoma Valentina Morandi1, Alessandro Biglia2, Francesco Maggiore1, Sofia Chiricolo1, Silvia Sammorì1, Maria Cristina Sacchi3|4, Edoardo Cammarata5, Maria Rosa Pellico6, Luigi Mario Castello2|3|7. | 1Dipartimento di Medicina Interna, SSD Reumatologia, AOUAL Santi Antonio e Biagio e Cesare Arrigo, Alessandria, Italy; 2 Dipartimento di Medicina Interna, AOUAL Santi Antonio e Biagio e Cesare Arrigo, Alessandria, Italy; 3Dipartimento di laboratorio di tecnologia, ricerca e innovazione DAIRI, AOUAL Santi Antonio e Biagio e Cesare Arrigo, Alessandria, Italy; 4AOUAL Santi Antonio e Biagio e Cesare Arrigo, Laboratorio Analisi, Alessandria, Italy; 5AOUAL Santi Antonio e Biagio e Cesare Arrigo, Dipartimento di Medicina Interna, SSD Dermatologia, Alessandria, Italy; 6ASST Gaetano Pini, divisione di Reumatologia Clinica, Milano, Italy; 7Università del Piemonte orientale, dipartimento di Medicina Traslazione, Novara, Italy.
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PO:16:236 | Achieving a low disease activity state with a corticosteroid dose of 5 mg or less: observational study with anifrolumab in patients with systemic lupus erythematosus in Italy Alessandra Bortoluzzi1, Fulvia Ceccarelli2, Fabio Leo3, Paola Roccatagliata3, Chiara Tani4, Margherita Zen5 | 1Azienda Ospedaliera Universitaria Sant' Anna di Cona, Università di Ferrara Italy; 2Unità di Reumatologia, Università Sapienza Roma Italy; 3AstraZeneca S.p.a. Milano Italy; 4Università di Pisa e Azienda Ospedaliero Universitaria Pisana, Pisa Italy; 5Dipartimento di Medicina DIMED , Divisione di Reumatologia, Università di Padova, Italy
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PO:31:165 | Prevalence and incidence of skin telangectasia and their association with clinical features: analysis of the European Scleroderma Trials and Research cohort Gemma Lepri1, Lorenzo Tofani2, Silvia Bellando Randone1, Veronica Batani3, Paolo Airò4, Patricia Carreira5, Joerg Henes6, Alexandra Balbir Gurman7, Florenzo Iannone8, Antonella Marcoccia9, Luc Mouthon10, Branimir Anic11, Carolina De Souza Müller12, Armine Haroyan13, Ana Cristina Cordeiro14, Serena Guiducci And Eustar Coll1. | 1University of Florence, Dept of Experimental and Clinical Medicine, AOU Careggi, Division of Rheumatology Florence Italy; 2University of Florence, Dept of Statistics, Informatics, Applications, Florence, Italy; 3Unit of Immunology, Rheumatology, Allergy and Rare Diseases UnIRAR, IRCCS San Raffaele, Milano, Italy; 4Scleroderma Unit, UOC Rheumatology and Clinical Immunology, ASST Spedali Civili, Brescia, Italy; 5Dept of Rheumatology, 12 de Octubre University Hospital, Madrid, Spain; 6Centre for Interdisciplinary Rheumatology, Immunology and autoimmune diseases INDIRA, University Hospital Tuebingen, Tuebingen, Germany; 7Rheumatology Institute, Rambam Health Care Campus Haifa Israel; 8Dept of Precision and Regenerative Medicine and Ionian Area, University of Bari, Bari, Italy; 9Interdisciplinary Reference Center for Systemic Sclerosis CRIIS Sandro Pertini Hospital, Rome, Italy; 10Dept of Internal Medicine, Cochin Hospital, Paris Cité University, Paris, France; 11Div Clinical Immunology and Rheumatology, Dept Internal Medicine, School of Medicine, University Hospital Center Zagreb, Zagreb, Croatia; 12Rheumatology Division, Hospital de Clínicas da Universidade Federal do Parana, Curitiba, Brazil; 13Dept of Rheumatology, Yerevan State Medical University of Armenia, Yerevan, Armenia; 14Servico Reumatologia Hospital Garcia de Orta Almada, Almada, Portugal.
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PO:16:232 | Belimumab step-down dose spacing in patients with systemic lupus erythematosus in persistent clinical remission: experience from a multicentric cohort Alice Bartoletti1, Laura Giudice1, Lorenza Maria Argolini1|2, Giuseppe Alvise Ramirez3, Luca Moroni3, Tommaso Schioppo4, Chiara Bellocchi5|6, Annalaura Fasiello6, Lorenzo Beretta6, Lorenzo Dagna3, Roberto Caporali1, Maria Gerosa1. | 1UO Clinica Reumatologica, ASST Gaetano Pini CTO, Milano, Italy; 2UOC Medicina fisica e riabilitazione specialistica, ASST Gaetano Pini CTO, Milano, Italy; 3Unit of Immunology, Rheumatology, Allergy and Rare Diseases, IRCCS San Raffaele Hospital, Vita-Salute San Raffa Milano Italy; 4Medicina Generale II, Servizio di Reumatologia, Ospedale San Paolo, ASST Santi Paolo Carlo, Milano, Italy; 5Department of Clinical Sciences and Community Health, University of Milan, Dipartimeto di Eccellenza 2023-2027, Milano, Italy; 6Referral Centre for Systemic Autoimmune DIseases, Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico, Milano, Italy
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PO:24:058 | Serum ferritin as a biomarker in idiopathic inflammatory myopathies with interstitial lung disease: baseline levels and longitudinal trends Silvia Grazzini1, Edoardo Conticini1, Marco Fornaro2, Chiara Rizzo3, Federica Camarda3, Paolo Cameli4, Miriana D'Alessandro4, Lidia La Barbera3, Stefano Stano2, Maria Rosa Pellico5, Latika Gupta6, Florenzo Iannone2, Giuliana Guggino3, Elena Bargagli4, Nicoletta Del Papa5, Luca Cantarini1, Bruno Frediani1. | 1Reumatologia, Dipartimento di Scienze Mediche, Chirugiche e Neuroscienze, Università di Siena, Siena, Italy; 2Reumatologia, Dipartimento di Emergenza e Trapianto d'Organo, Università di Bari, Bari, Italy; 3Reumatologia, Promozione della Salute, Materno-Infantile, di Medicina Interna e Specialistica, Università di Palermo, Palermo, Italy; 4Pneumologia, Dipartimento di Scienze Mediche, Chirugiche e Neuroscienze, Università di Siena, Siena, Italy; 5Reumatologia Clinica e Scienze Mediche, ASST Gaetano Pini CTO, Milano, Italy; 6University of Manchester, Manchester, United Kingdom.
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PO:26:095 | Educational online webinars of European Reference Network on rare and complex connective tissue and musculoskeletal diseases for patients, caregivers and healthcare professionals: six years' experience Emanuele Gotelli1|2, Rosanna Campitiello1|3, Eric Hachulla4|5|6, Vanessa Smith7|8|9, Joao Eurico Fonseca10|11, Tadej Avcin12|13, Gabriele Simonini14|15, Silvia Aguilera16, Lisa Matthews17, Charissa Frank18, Wiebke Lautré19, Monica Testoni20, Diana Marinello20, Rosaria Talarico20, Marta Mosca20, Maurizio Cutolo1|2. | 1Department of Internal Medicine and Specialties, University of Genova, Genova, Italy; 2IRCCS Ospedale Policlinico San Martino, Genova, Italy; 3Department of Experimental Medicine DIMES, University of Genova, Genova, Italy; 4Institute for Translational Research in Inflammation INFINITE, Université de Lille, Lille, France; 5INSERM, Lille, France; 6Centre de référence des maladies autoimmunes systemiques rares du Nord et Nord-Ouest de France CeRAINO, Lille, France; 7Department of Internal Medicine, University of Ghent, Ghent University Hospital, Ghent, Belgium; 8Department of Rheumatology, University of Ghent, Ghent University Hospital, Ghent, Belgium; 9Unit for Molecular Immunology and Inflammation, Flemish Institute for Biotechnology, Inflammation Research Center, Ghent, Belgium; 10Centro Hospitalar Universitário Lisboa Norte EPE, Serviço de Reumatologia e Doenças Ósseas Metabólicas Lisboa Portugal; 11Universidade de Lisboa, Unidade de Investigação em Reumatologia, Instituto de Medicina Molecular João Lobo Antunes Lisboa Portugal; 12University Children Hospital, University Medical Center Ljubljana, Ljubljana, Slovenia; 13University of Ljubljana, Department of Paediatrics, Ljubljana, Slovenia; 14University of Florence, NEUROFARBA Department, Firenze, Italy; 15Meyer Children Hospital IRCCS, Rheumatology Unit, Firenze, Italy; 16Spanish Association for Antiphospholipid Syndrome, Elche, Spain; 17Relapsing Polychondritis Awareness and Support, Worcester, United Kingdom; 18Flemish Association for Hereditary Connective Tissue Disorders, Koersel, Belgium; 19CHU Bordeaux Pellegrin, Centre de Références Maladies Auto-Immunes Systémiques Rares, Bordeaux, France; 20Azienda Ospedaliero Universitaria Pisana, Pisa, Italy.
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PO:19:286 | Genetic testing reveals an unexpected case of mevalonate kinase deficiency in a 37-year-old patient with AA renal amyloidosis and good response to colchicine Francesca Crisafulli1, Paolo Airò2, Federica Mescia3, Gianmarco Lugli3, Gianfranco Savoldi4, Claudia Izzi3|5, Federico Alberici3, Marco Cattalini6, Franco Franceschini1, Micol Frassi2. | 1Rheumatology and Clinical Immunology Unit, ASST Spedali Civili and University of Brescia, Brescia, Italy; 2Rheumatology and Clinical Immunology Unit, ASST Spedali Civili of Brescia, Brescia, Italy; 3U.O Nefrologia, ASST Spedali Civili di Brescia e Università degli Studi di Brescia, Brescia, Italy; 4Medical genetics Laboratory, Laboratory Department ASST Spedali Civili di Brescia, Brescia, Italy; 5Struttura Complessa di Genetica Clinica, ASST Spedali Civili di Brescia, Brescia, Italy; 6Pediatrics Clinic, University of Brescia and ASST Spedali Civili of Brescia, Brescia, Italy.
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PO:31:174 | Increased frequency of anti-RNA polymerase 3 antibodies in patients with systemic sclerosis and silicone breast implants: a multicentre study from the international European Scleroderma Trials and Research cohort Maria Grazia Lazzaroni1, Yolanda Braun-Moscovici2, Elda Piovani1, Claudia Barison1, Liala Moschetti1, Veronica Batani3, Corrado Campochiaro3, Michal Tomcik4, Francesca Motta5, Maria De Santis5, Petros P. Sfikaki6, Masataka Kuwana7, Brigitte Granel8, Roberta Foti9, Virginia Berlingiero10, Joana Caetano11, Yannick Allanore12, Alexandra Balbir-Gurman2, Marco Matucci Cerinic3, Franco Franceschini1, Paolo Airò1. | 1ASST Spedali Civili of Brescia, University of Brescia, Brescia, Italy; 2Rambam Health Care Campus, Rappaport Faculty of Medicine, Technion-Israeli Institute of Tecnology, Haifa, Israel; 3Vita-Salute San Raffaele University, San Raffaele Hospital, Milano, Italy; 4Institute of Rheumatology, Praga, Czech Republic; 5IRCCS Humanitas Research Hospital; Humanitas University, Milano, Italy; 6Joint Rheumatology Program, Medical School, National Kapodistrian University of Athens Atene GREECE; 7Nippon Medical School Hospital Tokyo Japan; 8Hôpital Nord de Marseille; Aix-Marseille Université Marsiglia France; 9AOU Policlinico G. Rodolico San Marco, Catania, Italy; 10Azienda Ospedaliera Universitaria Senese, Siena, Italy; 11Fernando Fonseca Hospital, Amadora, Portugal; 12Université Paris Cité, Cochin Hospital, Parigi, France.
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PO:32:185 | Deep-learning analysis of high-resolution computed tomography images predicts progression and mortality in systemic sclerosis related interstitial lung disease Valentina Boni1, Rosa D'Abronzo2, Piergiacomo Cerasuolo1, Lucio Calandriello2, Giuseppe Cicchetti2, Gerlando Natalello1, Bruno Iovene5, Francesco Varone5, Giacomo Sgalla5, Luca Richeldi5, Anna Rita Larici2|4, Maria Antonietta D'Agostino1|3, Silvia Laura Bosello1|3, Enrico De Lorenzis1. | 1Division of Rheumatology and Clinical Immunology Catholic Univeristy of the Sacred Heart, Rome, Italy; 2Department of Diagnostic Imaging, Oncological Radiotherapy and Hematology, Diagnostic Imaging Area, Catholic University, Rome, Italy; 3Department of Geriatric and Orthopaedic Sciences, Catholic Univeristy of the Sacred Heart, Rome, Italy; 4Department of Radiological and Hematological Sciences, Section of Radiology, Catholic Univeristy of the Sacred Heart, Rome, Italy; 5Division of Pulmonary Medicine, Catholic University of the Sacred Heart, Roma, Italy.
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PO:35:228 | Polymyalgia rheumatica and giant cell arteritis induced by immune checkpoint inhibitors for cancer treatment: a systematic review and meta-analysis highlighting differences from the idiopathic forms Elvis Hysa1, Andrea Casabella2, Emanuele Gotelli1, Rosanna Campitiello1, Carlo Genova3, Enrica Teresa Tanda4, Carmen Pizzorni1, Alberto Sulli1, Vanessa Smith5, Marco Amedeo Cimmino6, Sabrina Paolino1, Maurizio Cutolo1. | 1Laboratory of Experimental Rheumatology and Academic Division of Clinical Rheumatology, Department of Internal Medicine, Genova, Italy; 2IRCCS Ospedale Policlinico San Martino, Genova, Italy; 3Academic Oncology Unit; IRCCS Ospedale Policlinico San Martino, Genova, Italy; 4UOC Medical Oncology Clinic 2, Department of Internal Medicine, University of Genova, Genova, Italy; 5Department of Internal Medicine, Ghent University, Department of Rheumatology, Ghent University Hospital, Ghent, Belgium; 6Rheumatology Outpatient Clinic, Villa Ravenna Chiavari Italy.
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PO:32:176 | Outcomes of upfront combination vs monotherapy with rituximab or mycophenolate mofetil for systemic sclerosis interstitial lung disease: results from a European Scleroderma Trials and Research cohort study Devis Benfaremo1, Corrado Campochiaro2, Gábor Kumánovics3, Christina Bergmann4, Elisabetta Zanatta5, David Launay6, Serena Guiducci7, Mickael Martin8, Carolina De Souza Müller9, Carlomaurizio Montecucco10, Luc Mouthon11, Gabriella Szucs12, Kastriot Kastrati13, Marie-Elise Truchetet14, Madelon Vonk15, Francesco Del Galdo16, Marco Matucci-Cerinic2, Gianluca Moroncini1, Yannick Allanore17. | 1Department of Clinical and Molecular Sciences, Marche Polytechnic University, Marche University Hospital, Ancona, Italy; 2Vita-Salute San Raffaele University, San Raffaele Hospital, Milano, Italy; 3University of Pécs, Department Of Rheumatology And Immunology, Pécs, Hungary; 4University Hospital Erlangen, Department Internal Medicine 3, Erlangen, Germany; 5Padova University Hospital, Rheumatology Unit, Padova, Italy; 6Univ. Lille, Inserm, CHU Lille, Department of Internal Medicine and Clinical Immunology, Lille, France; 7University of Florence, Azienda Ospedaliera Universitaria Careggi, Firenze, Italy; 8Poitiers University Hospital, Department of Internal Medicine Poitiers France; 9Hospital de Clinicas da Universidade Federal do Parana Curitiba Brazil; 10Università di Pavia e IRCCS Fondazione Policlinico S. Matteo, Pavia, Italy; 11Hôpital Cochin, Department of Internal Medicine, Paris, France; 12University of Debrecen, Faculty of Medicine, Department of Rheumatology, Debrecen, Hungary; 13Medical University of Vienna, Department of Medicine III, Division of Rheumatology, Vienna, Austria; 14CHU de Bordeaux, Rheumatology department, Bordeaux, France; 15Radboudumc, Department of Rheumatology Nijmegen The Netherlands; 16Leeds Raynauds and Scleroderma Program, NIHR Biomedical Research Centre, Leeds, United Kingdom; 17Université Paris Cité, Cochin Hospital, Rheumatology Department, Paris, France.
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S13:5 | Association between vasoactive-vasodilating therapy and reduced detection of pulmonary arterial hypertension in systemic sclerosis: evidence from a European Scleroderma Trials and Research study Nicola Farina1, Silvia Bellando-Randone1, Sebastien Sanges2, Hilde Jenssen Bjørkekjær3, Lorenzo Tofani4, Marie-Elise Truchetet5, Vanessa Smith6, Andra Balanescu7, Christina Bergmann8, Yannick Allanore9, Philipp Klemm10, Simona Truglia11, Luca Idolazzi12, Christopher Denton13, Roberta Foti14, Anna Wojteczek15, Emmanuel Chatelus16, Madelon Vonk17, Serena Guiducci1, David Launay2, Eric Hachulla2, Jeska De Vries-Bouwstra18, Anna-Maria Hoffmann-Vold19, Oliver Distler20, Marco Matucci-Cerinic1, Cosimo Bruni1. | 1Department of Experimental and Clinical Medicine, Scleroderma Unit, Division of Rheumatology, University of Florence, Az, Firenze, Italy; 2Univ. Lille, Inserm, CHU Lille, Department of Internal Medicine and Clinical Immunology, Reference Center for Rare Autoi, Lille, France; 3Department of Rheumatology, Hospital of Southern Norway, Kristiansand, Norway; 4Department of Statistics, Informatics and Applications, University of Florence, Firenze, Italy; 5Rheumatology department, CHU de Bordeaux, Bordeaux, France; 6University of Ghent, Department of Rheumatology, Gent, Belgium; 7Department of Rheumatology, St. Maria Hospital, Carol Davila, University of Medicine and Pharmacy Bucharest Romania; 8Department Internal Medicine 3, University Hospital Erlangen, Erlangen, Germany; 9Rheumatology Department, Université Paris Cité, Cochin Hospital, Paris, France; 10Department of Rheumatology and Clinical Immunology Center, JLU Giessen, Campus Kerckhoff Bad Nauheim Germany; 11Reumatologia, Azienda Ospedaliero-Universitaria Policlinico Umberto I, Roma, Italy; 12Section of Rheumatology, Department of Medicine, University of Verona, Verona, Italy; 13Centre for Rheumatology, Royal Free London and University College London Medical School, London, United Kingdom; 14Division of Rheumatology, A.O.U. Policlinico-San Marco, Catania, Italy; 15Department of Rheumatology, Clinical Immunology, Geriatrics and Internal Medicine, Medical University of Gdansk, Univers Gdansk Poland; 16Department of Rheumatology, University Hospital Strasbourg Strasbourg France; 17Department of rheumatology, Radboud University Nijmegen Medical Center Nijmegen The Netherlands; 18Department of Rheumatology, Leiden University Medical Center Leiden The Netherlands; 19Department of Rheumatology, Oslo University Hospital, Oslo, Norway; 20Department of Rheumatology, University Hospital Zurich, University of Zurich, Zurich, Switzerland.
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