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PO:12:186 | Clinical, functional, and microvascular features in the early diagnosis and management of pulmonary hypertension in systemic sclerosis: the importance of multimodal screening strategies Irene Carlino1, Stefania Bisogno1, Alberto Palazzuoli2, Luigi Gennari1 | 1U.O.C. Reumatologia, Dipartimento di Scienze Mediche, Chirurgiche e Neuroscienze, Università di Siena, A.O.U. Senese; 2Azienda Sanitaria Locale, Novara, Italy
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S13:5 | Association between vasoactive-vasodilating therapy and reduced detection of pulmonary arterial hypertension in systemic sclerosis: evidence from a European Scleroderma Trials and Research study Nicola Farina1, Silvia Bellando-Randone1, Sebastien Sanges2, Hilde Jenssen Bjørkekjær3, Lorenzo Tofani4, Marie-Elise Truchetet5, Vanessa Smith6, Andra Balanescu7, Christina Bergmann8, Yannick Allanore9, Philipp Klemm10, Simona Truglia11, Luca Idolazzi12, Christopher Denton13, Roberta Foti14, Anna Wojteczek15, Emmanuel Chatelus16, Madelon Vonk17, Serena Guiducci1, David Launay2, Eric Hachulla2, Jeska De Vries-Bouwstra18, Anna-Maria Hoffmann-Vold19, Oliver Distler20, Marco Matucci-Cerinic1, Cosimo Bruni1. | 1Department of Experimental and Clinical Medicine, Scleroderma Unit, Division of Rheumatology, University of Florence, Az, Firenze, Italy; 2Univ. Lille, Inserm, CHU Lille, Department of Internal Medicine and Clinical Immunology, Reference Center for Rare Autoi, Lille, France; 3Department of Rheumatology, Hospital of Southern Norway, Kristiansand, Norway; 4Department of Statistics, Informatics and Applications, University of Florence, Firenze, Italy; 5Rheumatology department, CHU de Bordeaux, Bordeaux, France; 6University of Ghent, Department of Rheumatology, Gent, Belgium; 7Department of Rheumatology, St. Maria Hospital, Carol Davila, University of Medicine and Pharmacy Bucharest Romania; 8Department Internal Medicine 3, University Hospital Erlangen, Erlangen, Germany; 9Rheumatology Department, Université Paris Cité, Cochin Hospital, Paris, France; 10Department of Rheumatology and Clinical Immunology Center, JLU Giessen, Campus Kerckhoff Bad Nauheim Germany; 11Reumatologia, Azienda Ospedaliero-Universitaria Policlinico Umberto I, Roma, Italy; 12Section of Rheumatology, Department of Medicine, University of Verona, Verona, Italy; 13Centre for Rheumatology, Royal Free London and University College London Medical School, London, United Kingdom; 14Division of Rheumatology, A.O.U. Policlinico-San Marco, Catania, Italy; 15Department of Rheumatology, Clinical Immunology, Geriatrics and Internal Medicine, Medical University of Gdansk, Univers Gdansk Poland; 16Department of Rheumatology, University Hospital Strasbourg Strasbourg France; 17Department of rheumatology, Radboud University Nijmegen Medical Center Nijmegen The Netherlands; 18Department of Rheumatology, Leiden University Medical Center Leiden The Netherlands; 19Department of Rheumatology, Oslo University Hospital, Oslo, Norway; 20Department of Rheumatology, University Hospital Zurich, University of Zurich, Zurich, Switzerland.
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PO:31:169 | From Crisis to Chronicity: A Real-World Study of Renal Dysfunction in Systemic Sclerosis Stefano Stano1, Fabio Cacciapaglia1|2, Giorgia Campanale1, Simone Perniola1, Maria Morrone1, Andrea Cito1, Vincenzo Venerito1, Maria Grazia Anelli1, Giuseppe Lopalco1, Florenzo Iannone1 | 1Rheumatology Unit - Department of Precision and Regenerative Medicine, Jonian Area DiPReMeJ, University of Bari Bari, Italy; 2Rheumatology Service, Internal Medicine Unit F. Miulli General Hospital, Department of Medicine and Surgery, LUM Casamassima, Italy
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PO:12:180 | Echocardiographic screening of pulmonary hypertension in a multidisciplinary cohort of patients with interstitial lung disease Lorenzo Mattia Bianchessi1, Veronica Piccin1, Federica Sabatelli1, Lorenzo Cavagna1, Giovanni Zanframundo1, Domenicafederica Briganti2, Mauro Acquaro3, Stefano Ghio3, Domenico Sorace1, Valentina Vertui2, Ilaria Giana2, Andrea Patanè3, Veronica Codullo1 | 1UOC Reumatologia, Fondazione IRCCS Policlinico S. Matteo, Pavia; 2Centro Trapianti, Fondazione IRCCS Policlinico San Matteo, Pavia; 3UOC Cardiologia, Fondazione IRCCS Policlinico San Matteo, Pavia, Italy
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PO:32:178 | Effectiveness of oral anticoagulants in precapillary pulmonary hypertension associated with systemic sclerosis: a EUSTAR cohort study Nicola Farina1, Silvia Bellando-Randone1, Hilde Jenssen-Bjørkekjær2, David Launay3, Patricia Carreira4, Paolo Airò5, Serena Guiducci1, Dilia Giuggioli6, Gabriela Riemekasten7, Carmen-Pilar Simeón Aznar8, Christina Bergmann9, Elise Siegart10, Ivan Castellví11, Lesley Ann Saketkoo12, Jeska De Vries-Bouwstra13, Philipp Klemm14, Ulf Müller-Ladner14, Alexandra Balbir-Gurman15, Vanessa Smith16, Florenzo Iannone17, Luca Idolazzi18, Christopher Denton19, Edoardo Rosato20, Britta Maurer1, Yannick Allanore1, Yoshiya Tanaka1, Elisabetta Zanatta1, Oliver Distler1, Marco Matucci-Cerinic1, Cosimo Bruni1 | 1Department of Experimental and Clinical Medicine, Scleroderma Unit, Division of Rheumatology, University of Florence, Az Firenze, Italy; 2Department of Rheumatology, Hospital of Southern Norway Kristiansand, Norway; 3National Reference Center for Pulmonary Arterial Hypertension Pulmotension Lille, France; 4Hospital Universitario 12 de Octubre, Rheumatology Department Madrid Spain; 5ASST Spedali Civili of Brescia, University of Brescia, Rheumatology and Clinical Immunology Unit Brescia, Italy; 6Scleroderma Unit, Rheumatology Unit, University Hospital of Modena and Reggio Emilia Modena, Italy; 7Universitätsklinikum Schleswig-Holstein, Klinik für Rheumatologie und klinische Immunologie Lübeck Germany; 8Hospital Universitario Vall d'Hebron, Department of Internal Medicine, Systemic Autoimmune Diseases Unit Barcelona Spain; 9University Hospital Erlangen, Department Internal Medicine 3 Erlangen Germany; 10Charité University Hospital, Department of Rheumatology Berlin Germany; 11Hospital de la Santa Creu i Sant Pau Baercelona Spain; 12New Orleans Scleroderma and Sarcoidosis Patient Care and Research Center New Orleans, USA; 13Leiden University Medical Center, Department of Rheumatology Leiden, The Netherlands; 14JLU Giessen, Campus Kerckhoff, Department of Rheumatology and Clinical Immunology Center Bad Nauheim Germany; 15Rambam Health Care Campus, Rheumatology Institute Haifa, Israel; 16University of Ghent, Department of Rheumatology Ghent, Belgium; 17Rheumatology DiMePReJ, University of Bari, School of Medicine Bari, Italy; 18University of Verona, Section of Rheumatology, Department of Medicine Verona, Italy; 19Royal Free London and University College London Medical School, Centre for Rheumatology London, United Kingdom; 20Sapienza University of Rome, Department of Translational and Precision Medicine Azienda Ospedaliero-Universitaria Policl Roma, Italy
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PO:31:166 | S'/PAPs ratio in systemic sclerosis: a promising non-invasive index for early detection and prognosis of pulmonary hypertension. A step toward more accurate screening? Marco De Pinto1, Amelia Spinella1, Pierluca Macripò2, Alessia Laneri1, Benedetta Bongiovanni1, Maria Grazia Malandra1, Martina Orlandi1-3, Gianluca Pagnoni2, Arianna Maini2, Rosario Rossi2-4, Clodoveo Ferri1, Francesca Coppi2-3, Dilia Giuggioli1-3. | 1Rheumatology Unit, Azienda Ospedaliero-Universitaria Policlinico di Modena, University of Modena and Reggio Emilia, Modena, Italy; 2Cardiology Division, Azienda Ospedaliero-Universitaria Policlinico di Modena, Modena, Italy; 3Department of Medical and Surgical Sciences for Children and Adults, University of Modena and Reggio Emilia, Modena, Italy; 4Department of Biomedical, Metabolic and Neural Sciences, University of Modena and Reggio Emilia, Modena, Italy.
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CO:03:1 | Distinct breath metabolomic signature in systemic sclerosis patients with pulmonary arterial hypertension Martina Iacubino1, Lorenzo Rocco1, Marco Vicenzi2|3, Chiara Bellocchi2|4, Marta Mozzo4, Adriana Severino3, Monica Caronni3, Alessandro Santaniello3, Gaia Montanelli3, Barbara Vigone3, Liam Grimmett5, Matthew Kerr5, Lorenzo Beretta3. | 1Scuola di specializzazione in Allergologia e Immunologia clinica, Università degli Studi di Milano; 2Dipartimento di Scienze Cliniche e Salute di Comunità, Dipartimento di Eccellenza 2023-2027, Università degli Studi di Milano; 3Dipartimento di Malattie Cardio-Toraciche-Vascolari, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milano; 4Dipartimento di Immunologia Clinica e Medicina Interna, Scleroderma Unit - Fondazione IRCCS Ca' Granda Ospedale Maggiore, Milano, Italy; 5Owlstone Medical, Cambridge, UK
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PO:17:254 | Systemic lupus erythematosus with pulmonary involvement: clinical insights from an Albanian cohort Arbi Pecani1, Arian Mezini2, Loreta Karaulli2, Laert Gjati2, Silvana Bala2 | 1Reumatologia, Dipartimento di Medicina Interna, Università di Medicina di Tirana, Ospedale Universitario Shefqet Ndroqi, Tirana; 2Pneumologia, Dipartimento di Medicina Respiratoria, Ospedale Universitario Shefqet Ndroqi, Tirana, Albania
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PO:10:150 | A case of pulmonary hypertension in Whipple's disease Alba Chiara Pozzi1|2, Giulia Fontana1|2, Francesca Crisafulli1|2, Guarino Daniele3, Monica Salvi3, Massimiliano Palazzini3, Francesco Biagi4|5, Ilaria Cavazzana1|2, Franco Franceschini1|2, Micol Frassi1. | 1Rheumatology and Clinical Immunology Unit ERN-ReCONNECT, ASST Spedali Civili, Brescia, Italy; 2Department of Clinical Experimental Sciences, University of Brescia, Brescia; 3IRCCS Azienda Ospedaliero-Universitaria di Bologna, University of Bologna, Cardiology Unit, DIMEC, Bologna; 4University of Pavia, Department of Internal Medicine and Therapeutics, Pavia; 5Istituti Clinici Scientifici Maugeri IRCCS, Gastroenterology Unit of Pavia Institute, Pavia, Italy.
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PO:12:187 | Maternal Hypertensive Disorders in Pregnant Women with Rheumatic Diseases and long-term Cardiovascular Outcomes: preliminary data of a single centre experience Margherita Rinaldi1, Paolo Semeraro1, Francesca Crisafulli1, Matteo Filippini2, Maria Grazia Lazzaroni1, Cecilia Nalli1, Liala Moschetti1, Marco Taglietti2, Chiara Loardi3, Rossana Orabona3, Francesca Ramazzotto3, Sonia Zatti3, Laura Andreoli1, Angela Tincani1, Micaela Fredi1, Ilaria Cavazzana1, Franco Franceschini1 | 1Department of Clinical and Experimental Sciences, University of Brescia, Italy; 2Rheumatology and Clinical Immunology, ASST Spedali Civili of Brescia, ERN-ReCONNET Center Brescia, Italy; 3Gynaecology and Obstetrics Unit ASST Spedali Civili di Brescia, Italy
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PO:35:227 | Long-term renal and survival outcomes in microscopic polyangiitis: data from an observational monocentric cohort Roberta Prevedello1, Federica Davanzo1, Luca Iorio1, Eleonora Fiorin1, Marta Codirenzi1, Roberto Padoan1, Andrea Doria1. | 1Unità di Reumatologia, Dipartimento di Medicina DIMED, Università degli Studi di Padova, Padova, Italy.
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CO:08:2 | Impact of comorbidities on clinical-serological phenotype of primary Sjögren's disease: a retrospective analysis of a multicenter cohort Roberto Dal Pozzolo1, Maria Letizia Currò2, Giacomo Cafaro1, Valeria Manfrè3, Gaetano La Rocca4, Alessia Alunno5, Francesco Carubbi5, Nicoletta Del Papa6, Viktoriya Pavlych7, Ilenia Fischetti8, Letizia Pia Di Corcia9, Pamela Bernardini10, Luca Quartuccio3, Chiara Baldini4, Paola Cipriani7, Roberta Priori8, Onorina Berardicurti9, Serena Guiducci10, Serena ColaFrancesco11, Fabiola Atzeni2, Elena Bartoloni1. | 1SC Reumatologia. Università di Perugia; 2Unità di Reumatologia. Università di Messina; 3Unità di Reumatologia, Università di Udine; 4Unità di Reumatologia. Università di Pisa; 5Divisione di Medicina Interna e Nefrologia. Università di L'Aquila; 6Dipartimento di Reumatologia. Università di Milano; 7Unità di Reumatologia, Università di L'Aquila; 8UOC Reumatologia. Università Sapienza, Roma; 9Unità di Reumatologia. Università Campus Biomedico, Roma; 10Unità di Reumatologia. Università di Firenze; 11Reumatologia e Immunologia Clinica. IRCCS Humanitas, Milano, Italy
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PO:33:194 | The role of anti-g protein-coupled receptors antibodies in the assessment of systemic sclerosis-primary heart involvement Beatrice Moccaldi1, Giovanni Civieri2, Annagrazia Cecere2, Marco Binda1, Marta Vadori2, Laura Iop2, Marta Tonello1, Anna Cuberli1, Andrea Benini1, Emanuele Cozzi2, Andrea Doria1, Francesco Tona2, Elisabetta Zanatta1|2. | 1Unità di Reumatologia, Dipartimento di Medicina DIMED, Università di Padova, Padova, Italy; 2Dipartimento di Scienze Cardio-Toraco-Vascolari e Sanità Pubblica, Università di Padova, Padova, Italy.
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PO:37:256 | Spontaneous renal artery dissection: a subtle presentation of a “vasculitis-mimicker” Federdo Nogarin1, Alfonso Valerio Massara1, Zairo Ferrante2, Filippo Furicchia3, Riccardo Bertola1, Elena Pollicelli1, Ilaria Calciolari1, Sopie Secka1, Andrea Lo Monaco1, Marcello Govoni1 | 1UOC Reumatologia; 2UOC Radiologia Ospedaliera; 3UOC Radiologia Vascolare e Interventistica, Arcispedale Sant'Anna, Ferrara, Italy
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PO:14:205 | Primary antiphospholipid antibody syndrome: association between new classification criteria manifestations and a higher-risk disease phenotype Sara Ferrigno1, Vittorio Forte2, Marco Panetta1, Sergio Lisena1, Giorgia Ranucci2, Luigi De Marco1, Elisabetta Greco1, Alberto Bergamini1, Maria Sole Chimenti1, Paola Conigliaro1. | 1Rheumatology, allergology and clinical immunology, Department of Systems Medicine, University of Rome Tor Vergata, Rome, Italy; 2Hematology, Department of Biomedicine and Prevention, University of Rome Tor Vergata, Rome, Italy.
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PO:24:064 | IPF vs CTD-ILD: Survival and Lung Function from an Italian Real-World Cohort Marco Fornaro1, Donato Lacedonia2, Lorenzo Cavagna3, Paolo Airò4, Marco Sebastiani5, Gianluca Sambataro6, Fabio Cacciapaglia7, Angelica Napoletano1, Cosimo De Pace2, Pasquale Tondo2, Giulia Scioscia2, Eleonora Pedretti4, Maria Grazia Lazzaroni4, Carlo Vancheri8, Andreina Manfredi9, Lorenzo Binchessi3, Rocco Capece3, Michele De Ceglie10, Massimo Giotta11, Florenzo Iannone1 | 1Unit of Rheumatology, Department of Precision and Regenerative Medicine - Area Jonica DiMePRe-J, University of Bari, Bari, Italy; 2Department of Medical and Surgical Sciences, University of Foggia Foggia, Italy; 3Department of Internal Medicine and Therapeutics, University of Pavia, Division of Rheumatology, Fondazione IRCCS, Pavia, Italy; 4Rheumatology and Clinical Immunology Unit, Department of Clinical and Experimental Sciences, ASST Spedali Civili Brescia, Italy; 5Rheumatology Unit, AUSL Piacenza, Department of Medicine and Surgery, University of Parma, Parma, Italy; 6Department of Medicine and Surgery, University of Enna Kore, Enna, Italy; 7Rheumatology Service, F. Miulli Hospital and Department of Medicine and Surgery, LUM University, Casamassima, Italy; 8Department of Clinical and Experimental Medicine, Regional Referral Center for Rare Lung Diseases, Catania, Italy; 9Rheumatology Unit, IRCCS Santa Maria Nuova Reggio Emilia, University of Modena, Modena, Italy; 10DIM, Interdisciplinary Department of Medicine, Section of Diagnostic Imaging, University of Bari, Bari, Italy; 11Health Prevention Department, Local Health Authority of Brindisi, Brindisi, Italy
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PO:33:197 | Systemic sclerosis and endothelial dysfunction: the passive leg movement technique in the assessment of no-mediated vascular impairment Silvia Guella1, Giovanni Baldassarre3, Alessandro Gratton2|3, Lucrezia Zuccarelli3, Elena Treppo2, Emma Di Poi2, Bruno Grassi3, Luca Quartuccio2|3 | 1SS Reumatologia-CMID Ospedale San Giovanni Bosco, Torino; 2Clinica di Reumatologia Ospedale Santa Maria della Misericordia, ASUFC, Udine; 3Dipartimento di Medicina, Università di Udine, Italy
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PO:25:075 | Cancer occurence in patients with idiopathic inflammatory myopathies: new insights from the analysis of a monocentric cohort Michele Diomedi1, Federico Fattorini1, Simone Barsotti2, Chiara Cardelli1|3, Elenia Laurino4, Alessandra Tripoli4, Linda Carli4, Marta Mosca1|4. | 1Rheumatology Unit, Department of Clinical and Experimental Medicine, University of Pisa, Pisa, Italy; 2Rheumatology, Versilia Hospital, Viareggio, Italy; 3Department of Medical Biotechnologies, University of Siena, Siena, Italy; 4Rheumatology Unit, AOUP, Pisa, Italy.
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CO:02:4 | Whole blood hypercoagulable profiles in patients with rheumatoid arthritis Lorenzo Di Luozzo1, Alessandro Giollo1, Mariangela Salvato1, Francesca Frizzera1, Kiren Khalid1, Luca Spiezia2, Andrea Benetti2, Chiara Samà2, Paolo Simioni2, Andrea Doria1. | 1Unità di Reumatologia, Azienda Ospedaliera di Padova; 2Dipartimento di Medicina, Università di Padova, Italy
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PO:32:180 | Clinical and hemodynamic profile of patients with SSC-PAH with and without pulmonary veno-occlusive disease: a single-center study Anna Cuberli1, Michele Strosio2, Alessandro Magi2, Beatrice Moccaldi1, Marco Binda1, Andrea Benini1, Andrea Doria1, Martina Perazzolo Marra2, Giulia Famoso2, Laura De Michieli2, Elisabetta Zanatta1|2 | 1UOC Reumatologia, DIDAS Medicina Dei SIstemi, Azienda Ospedale Università di Padova; 2UOC Cardiologia, DIDAS Medicina Dei Sistemi, Azienda Ospedale Università di Padova, Italy
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PO:37:263 | First non invasive visualization of vasculitis in the retinal arteries by high resolution optical coherence tomography in a patient with giant cell arteritis Ruggiero Mascolo1, Chiara Facoetti1, Claudia Nardi2, Stefano Erba2, Martina Martelli1, Gabriella Marinaro1, Giulia Dieguez1, Giacomo Iacomelli1, Chiara Carollo1, Michel Chevallard3, Bruno Lucchino3, Mariaeva Romano3, Andrea Locatelli3, Donatella Ventura3, Giovanna Randisi3, Giuliana La Paglia3, Alessandra Mutti3, Alessandro Invernizzi2, Stefano De Angelis2, Giovanni Staurenghi2, Antonio Brucato4, Enrico Tombetti4. | 1Dipartimento di Medicina Interna, ASST Fatebenefratelli-Sacco, Università degli studi di Milano, Milano, Italy; 2U.O. Oftalmologia, ASST Fatebenefratelli-Sacco, Università degli studi di Milano, Milano, Italy; 3U.O. Reumatologia, ASST Fatebenefratelli-Sacco, Università degli studi di Milano, Milano, Italy; 4Dipartimento di scienze cliniche e biomediche, ASST Fatebenefratelli-Sacco, Università degli studi di Milano, Milano, Italy.
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PO:23:055 | Overlap of systemic sclerosis and Sjögren’s disease: insights from an Italian case-control study Stefano Stano1, Fabio Cacciapaglia1|2, Maria Morrone1, Simone Perniola1, Marco Capodiferro1, Marco Fornaro1, Laura Coladonato1, Giuseppe Lopalco1, Florenzo Iannone1. | 1Rheumatology Unit - Department of Precision and Regenerative Medicine, Jonian Area DiPReMeJ, University of Bari, Bari, Italy; 2Rheumatology Service, Internal Medicine Unit F. Miulli General Hospital, Department of Medicine and Surgery, LUM Casamassima Italy.
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PO:36:252 | Long-Term Outcomes of Patients with Takayasu Arteritis in the Era of Biological Agents: a Multicenter International Study Alessandro Tomelleri1, Durga Prasanna Misra2, Fatma Alibaz-Oner3, Chiara Marvisi4, Chiara Calabrese1, Upendra Rathore2, Aysegul Avcu3, Adele Del Giudice4, Elisabetta Olivi4, Caterina Ricordi4, Corrado Campochiaro1, Elena Baldissera1, Marco Matucci-Cerinic1, Haner Direskeneli3, Carlo Salvarani4, Lorenzo Dagna1 | 1IRCCS Ospedale San Raffaele, Unità di Immunologia, Reumatologia, Allergologia e Malattie Rare Milano, Italy; 2Sanjay Gandhi Postgraduate Institute of Medical Sciences SGPGIMS, Clinical Immunology and Rheumatology Lucknow Country, India; 3Marmara University, School of Medicine, Department of Internal Medicine, Division of Rheumatology Istanbul, Turkey; 4Azienda USL-IRCCS di Reggio Emilia, Unità di Reumatologia Reggio Emilia, Italy
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PO:31:163 | Safety and tolerability of home-based prostacyclin analogue therapy in vascular manifestations of the scleroderma spectrum: results of a monocentric study Alice Dionisi1, Lucrezia Verardi2, Annacarla Finucci2, Paola Volpe2, Anna Cinzia Raspa2, Paola Cipriani1, Raffaele Zicolella2 | 1Reumatologia,Dipartimento di Sscienze Cliniche Applicate e Biotecnologiche, Università degli Studi dell'Aquila; 2UOC Reumatologia, Ospedale Civile di Pescara, Italy
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S13:6 | Investigating the intricate interplay between pulmonary functionality and advanced microangiopathy in very early diagnosis of systemic sclerosis Eugenio Capparelli1, Eleonora Zaccara1, Daniela Bompane1, Elisabetta Ricchiuto2, Giorgio Bonardi2, Laura Castelnovo1, Antonio Tamburello1, Antonino Mazzone3, Paola Faggioli1. | 1Rheumatology Unit; 2Pneumology Unit; 3Internal Medicine Unit, ASST Ovest Milanese, Legnano, Italy.
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