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• PO:10:150 | A case of pulmonary hypertension in Whipple's disease Alba Chiara Pozzi^1|2, Giulia Fontana^1|2, Francesca Crisafulli^1|2, Guarino Daniele³, Monica Salvi³, Massimiliano Palazzini³, Francesco Biagi^4|5, Ilaria Cavazzana^1|2, Franco Franceschini^1|2, Micol Frassi¹. | ¹Rheumatology and Clinical Immunology Unit ERN-ReCONNECT, ASST Spedali Civili, Brescia, Italy; ²Department of Clinical Experimental Sciences, University of Brescia, Brescia; ³IRCCS Azienda Ospedaliero-Universitaria di Bologna, University of Bologna, Cardiology Unit, DIMEC, Bologna; ⁴University of Pavia, Department of Internal Medicine and Therapeutics, Pavia; ⁵Istituti Clinici Scientifici Maugeri IRCCS, Gastroenterology Unit of Pavia Institute, Pavia, Italy.

  Società Italiana di Reumatologia

  26-11-2025

  https://doi.org/10.4081/reumatismo.2025.2026

  77

• CO:07:4 | Clinical and psychosocial domains in fibromyalgia: a multidimensional questionnaire approach for personalized management. Results from an Italian monocentric study Eleonora Pedretti¹, Francesca Regola¹, Giulia Fontana^1|2, Giulia Voltarel^1|2, Michela Riolfo^1|2, Anna Scalvini¹, Ilaria Cavazzana^1|2, Franco Franceschini^1|2, Roberto Gorla¹. | ¹Rheumatology and Clinical Immunology Unit - ERN ReCONNET, ASST Spedali Civili of Brescia; ²Department of Clinical and Experimental Sciences, University of Brescia, Italy

  Società Italiana di Reumatologia

  26-11-2025

  https://doi.org/10.4081/reumatismo.2025.1979

  104

• PO:16:238 | Cardiovascular risk in systemic lupus erythematosus patients: comparison among Framingham Score, QRISK3, and SLECRE Francesca Vignoni^1|2, Serena Iodice², Cesare Tomasi², Chiara Orlandi^1|2, Eleonora Pedretti¹, Micaela Fredi², Franco Franceschini^1|2, Ilaria Cavazzana^1|2. | ¹Rheumatology and Clinical Immunology Unit - ERN ReCONNET, ASST Spedali Civili of Brescia, Brescia, Italy; ²Department of Clinical and Experimental Sciences, University of Brescia, Brescia, Italy.

  Società Italiana di Reumatologia

  26-11-2025

  https://doi.org/10.4081/reumatismo.2025.2045

  74

• CO:10:2 | Common variable immunodeficiency patients complicated by autoimmune and inflammatory rheumatic manifestations reveal high frequency of genetic variants potentially linked to inborn errors of immunity Paolo Semeraro¹, Micol Frassi¹, Silvia Clara Giliani², Franco Franceschini¹, Paolo Airò¹. | ¹Rheumatology and Clinical Immunology Unit, ERN ReCONNET, ASST Spedali Civili of Brescia and University of Brescia; ²Medical Genetic Laboratory, ASST Spedali Civili of Brescia and University of Brescia, Italy

  Società Italiana di Reumatologia

  26-11-2025

  https://doi.org/10.4081/reumatismo.2025.1991

  70

• PO:15:219 | Nailfold capillaroscopic abnormalities in systemic lupus erythematosus: comparison with healthy controls and clinical-immunological correlations. Preliminary data Chiara Orlandi^1|2, Alessia Loda², Cesare Tomasi^1|2, Silvia Ebe Lucia Della Pina^1|2, Claudia Barison^1|2, Cecilia Nalli¹, Ilaria Cavazzana^1|2, Micaela Fredi^1|2, Franco Franceschini^1|2. | ¹Rheumatology and Clinical Immunology Unit - ERN ReCONNET , ASST Spedali Civili of Brescia, Brescia, Italy; ²Department of Clinical and Experimental Sciences, University of Brescia, Brescia, Italy.

  Società Italiana di Reumatologia

  26-11-2025

  https://doi.org/10.4081/reumatismo.2025.2039

  71

• PO:22:029 | Impact of mepolizumab on idiopathic hypereosinophilic syndromes: analysis of a monocentric retrospective cohort Jacopo Mora¹, Francesca Regola¹, Paola Toniati², Ilaria Cavazzana¹, Franco Franceschini¹. | ¹ASST Spedali Civili e Università degli Studi di Brescia, Brescia, Italy; ²ASST Spedali Civili di Brescia, Brescia, Italy.

  Società Italiana di Reumatologia

  26-11-2025

  https://doi.org/10.4081/reumatismo.2025.2053

  77

• CO:06:1 | Predictors of damage accrual in a monocentric cohort of patients with Behçet’s syndrome (BS) evaluated with BS overall damage index in real-life clinical practice Giulia Voltarel^1|2, Francesca Crisafulli^1|2, Alba Chiara Pozzi^1|2, Anita Melzani², Micol Frassi¹, Ilaria Cavazzana^1|2, Franco Franceschini^1|2, Paolo Airò¹. | ¹Rheumatology and Clinical Immunology Unit - ERN ReCONNET, ASST Spedali Civili of Brescia; ²Department of Clinical and Experimental Sciences, University of Brescia, Italy

  Società Italiana di Reumatologia

  26-11-2025

  https://doi.org/10.4081/reumatismo.2025.1973

  89

• PO:31:174 | Increased frequency of anti-RNA polymerase 3 antibodies in patients with systemic sclerosis and silicone breast implants: a multicentre study from the international European Scleroderma Trials and Research cohort Maria Grazia Lazzaroni¹, Yolanda Braun-Moscovici², Elda Piovani¹, Claudia Barison¹, Liala Moschetti¹, Veronica Batani³, Corrado Campochiaro³, Michal Tomcik⁴, Francesca Motta⁵, Maria De Santis⁵, Petros P. Sfikaki⁶, Masataka Kuwana⁷, Brigitte Granel⁸, Roberta Foti⁹, Virginia Berlingiero¹⁰, Joana Caetano¹¹, Yannick Allanore¹², Alexandra Balbir-Gurman², Marco Matucci Cerinic³, Franco Franceschini¹, Paolo Airò¹. | ¹ASST Spedali Civili of Brescia, University of Brescia, Brescia, Italy; ²Rambam Health Care Campus, Rappaport Faculty of Medicine, Technion-Israeli Institute of Tecnology, Haifa, Israel; ³Vita-Salute San Raffaele University, San Raffaele Hospital, Milano, Italy; ⁴Institute of Rheumatology, Praga, Czech Republic; ⁵IRCCS Humanitas Research Hospital; Humanitas University, Milano, Italy; ⁶Joint Rheumatology Program, Medical School, National Kapodistrian University of Athens Atene GREECE; ⁷Nippon Medical School Hospital Tokyo Japan; ⁸Hôpital Nord de Marseille; Aix-Marseille Université Marsiglia France; ⁹AOU Policlinico G. Rodolico San Marco, Catania, Italy; ¹⁰Azienda Ospedaliera Universitaria Senese, Siena, Italy; ¹¹Fernando Fonseca Hospital, Amadora, Portugal; ¹²Université Paris Cité, Cochin Hospital, Parigi, France.

  Società Italiana di Reumatologia

  26-11-2025

  https://doi.org/10.4081/reumatismo.2025.2075

  74

• PO:19:286 | Genetic testing reveals an unexpected case of mevalonate kinase deficiency in a 37-year-old patient with AA renal amyloidosis and good response to colchicine Francesca Crisafulli¹, Paolo Airò², Federica Mescia³, Gianmarco Lugli³, Gianfranco Savoldi⁴, Claudia Izzi^3|5, Federico Alberici³, Marco Cattalini⁶, Franco Franceschini¹, Micol Frassi². | ¹Rheumatology and Clinical Immunology Unit, ASST Spedali Civili and University of Brescia, Brescia, Italy; ²Rheumatology and Clinical Immunology Unit, ASST Spedali Civili of Brescia, Brescia, Italy; ³U.O Nefrologia, ASST Spedali Civili di Brescia e Università degli Studi di Brescia, Brescia, Italy; ⁴Medical genetics Laboratory, Laboratory Department ASST Spedali Civili di Brescia, Brescia, Italy; ⁵Struttura Complessa di Genetica Clinica, ASST Spedali Civili di Brescia, Brescia, Italy; ⁶Pediatrics Clinic, University of Brescia and ASST Spedali Civili of Brescia, Brescia, Italy.

  Società Italiana di Reumatologia

  26-11-2025

  https://doi.org/10.4081/reumatismo.2025.2049

  76

• CO:06:3 | Clinical and laboratory markers for distinguishing VEXAS from Schnitzler's syndrome in male patients with skin involvement: insights from the International AIDA Network Registries Valeria Caggiano¹, Jessica Sbalchiero¹, Micol Frassi², Andrea Hinojosa-Azaola³, Francesca Crisafulli², Franco Franceschini², Paolo Sfriso⁴, Sara Bindoli⁴, José Hernández-Rodríguez⁵, Henrique A. Mayrink Giardini⁶, Giuseppe Lopalco⁷, Florenzo Iannone⁷, Ombretta Viapiana⁸, Amato De Paulis⁹, Lorenzo Dagna¹⁰, Antonio Gidaro¹¹, Serena Bugatti¹², Matteo Piga¹³, Fabrizio Conti¹⁴, Rosetta Vitetta¹⁵, Cecilia Chighizola¹⁶, Marcello Govoni¹⁷, Giacomo Emmi¹⁸, Paola Triggianese¹⁹, Carmelo Gurnari¹⁹, Bruno Frediani¹, Claudia Fabiani¹, Luca Cantarini¹, Antonio Vitale¹, for the AIDA Network¹ | ¹Department of Medical Sciences, Surgery and Neurosciences, University of Siena; ²University of Brescia, Italy; ³Department of Immunology and Rheumatology, Mexico City, Mexico; ⁴Rheumatology Unit, University of Padova, Italy; ⁵Clinical Unit of Autoinflammatory Diseases, Hospital Clínic of Barcelona, Spain; ⁶Rheumatology Division, Universidade de São Paulo, Brazil; ⁷University of Bari; ⁸Rheumatology Unit, University and Azienda Ospedaliera Universitaria Integrata of Verona; ⁹University of Napoli "Federico II"; ¹⁰Università Vita-Salute San Raffaele, Milano; ¹¹Luigi Sacco Hospital, University of Milano; ¹²Università di Pavia; ¹³University and AOU of Cagliari; ¹⁴AOU Policlinico Umberto I, Sapienza University of Rome; ¹⁵Unit of Rheumatology, ASL Sant' Andrea Hospital, Vercelli; ¹⁶University of Milano; ¹⁷Azienda Ospedaliero-Universitaria S. Anna, Ferrara; ¹⁸University of Trieste; ¹⁹University of Rome-Tor Vergata, Rome, Italy.

  Società Italiana di Reumatologia

  26-11-2025

  https://doi.org/10.4081/reumatismo.2025.1975

  102

• PO:33:191 | Evaluation of the living with pulmonary fibrosis questionnaire in patients with systemic sclerosis associated interstitial lung disease: monocentric results Claudia Barison¹, Elda Piovani¹, Eleonora Pedretti¹, Eleonora Pazzi¹, Liala Moschetti¹, Ilaria Cavazzana¹, Franco Franceschini¹, Maria Grazia Lazzaroni¹, Paolo Airò¹. | ¹Rheumatology and Clinical Immunology, Scleroderma Unit, ASST Spedali Civili of Brescia, University of Brescia, Brescia, Italy.

  Società Italiana di Reumatologia

  26-11-2025

  https://doi.org/10.4081/reumatismo.2025.2082

  77

• PO:24:070 | Preliminary descriptive data from a single-centre cohort of patients with idiopathic inflammatory myopathy: focus on paraneoplastic and non-paraneoplastic patients Silvia Ebe Lucia Della Pina¹, Paola Bizioli¹, Samantha Mazza², Caproli Alessia¹, Cesare Tomasi¹, Ilaria Cavazzana¹, Franco Franceschini¹. | ¹S.C.O. Reumatologia ed Immunologia Clinica, ASST Spedali Civili di Brescia, Università degli Studi di Brescia, Brescia, Italy; ²Università degli Studi di Brescia, Brescia, Italy.

  Società Italiana di Reumatologia

  26-11-2025

  https://doi.org/10.4081/reumatismo.2025.2061

  76

• PO:35:219 | Real-world effectiveness of mepolizumab on gastrointestinal involvement in eosinophilic granulomatosis with polyangiitis and hypereosinophilic syndrome: a multicentre retrospective study Alessia Gatti¹, Francesca Regola¹, Giulia Fontana¹, Mario Addrea Piga², Gianluca Moroncini², Palma Carlucci³, Angelo Vacca³, Paolo Delvino⁴, Enrico Heffler⁵, Emanuele Nappi⁵, Jakub Moll⁶, Laura Losappio⁶, Jan Schroeder⁶, Federica Davanzo⁷, Roberto Padoan⁷, Edoardo Conticini⁸, Paolo Cameli⁸, Greta Pacini⁹, Alvise Berti⁹, Lorenzo Vrola¹⁰, Paola Tomietto¹⁰, Luca Quartuccio¹¹, Jan Willem Cohen Tervaert¹², Sabrina Arnold¹³, Peter Lamprecht¹³, Florence Roufosse¹⁴, Ilaria Cavazzana¹, Franco Franceschini¹, Giacomo Emmi¹⁵, Paola Toniati¹. | ¹Rheumatology and Clinical Immunology Unit, ERN ReCONNET, ASST Spedali Civili of Brescia and University of Brescia, Italy, Brescia, Italy; ²Università Politecnica delle Marche and Azienda Ospedaliero Universitaria delle Marche, Ancona, Italy, Ancona, Italy; ³Section of Internal Medicine 'Guido Baccelli', DiMePRe-J, University of Bari 'Aldo Moro', Bari, Italy, Bari, Italy; ⁴Rheumatology Unit, IRCCS San Gerardo dei Tintori, Monza, Italy Monza Italy; ⁵Department of Biomedical Sciences, Humanitas University and Personalized Medicine, Asthma and Allergy IRCCS Humanitas, Milano, Italy; ⁶Division of Allergy and Clinical Immunology, ASST GOM Niguarda, Milan, Italy, Milano, Italy; ⁷Rheumatology Unit, Department of Medicine DIMED, University of Padua, Padova, Italy, Padova, Italy; ⁸University of Siena, Siena, Italy, Siena, Italy; ⁹Santa Chiara Hospital and University of Trento, Unit of Rheumatology, Trento, Italy Trento Italy; ¹⁰UCO Medicina Clinica, ASUGI, Cattinara Teaching Hospital, Trieste, Italy, Trieste, Italy; ¹¹Division of Rheumatology, Department of Medicine ^DMED, University of Udine, Udine, Italy, Udine, Italy; ¹²University of Alberta, Edmonton, Alberta, Canada and Maastricht University, Maastricht, The Netherlands Maastricht The Netherlands; ¹³Department of Rheumatology and Clinical Immunology, University of Lübeck, Lübeck, Germany Lubeck Germany; ¹⁴Department of Internal Medicine, Hôpital Universitaire de Bruxelles - Erasme, Université Libre de Bruxelles, Belgium Brussels Belgium; ¹⁵Clinical Medicine and Clinical Immunology and Rheumatology Unit Cattinara University Hospital and University of Trieste, Trieste, Italy.

  Società Italiana di Reumatologia

  26-11-2025

  https://doi.org/10.4081/reumatismo.2025.2086

  97

• PO:17:253 | Unveiling the gap: a multicenter study on factors driving patient-physician discrepancies in assessing disease activity in systemic lupus erythematosus Giorgia Ingrid Gozzoli¹, Micaela Fredi¹, Federica Bonaso¹, Silvia Ebe Lucia Della Pina¹, Claudia Barison¹, Irene Lorenzini⁴, Raffaele Pericotti⁴, Anna Mattiuzzo⁴, Marcelo Neto², Sofia Azevedo³, Cláudia Oliveira³, Cesare Tomasi⁴, Luís Sousa Inês², Franco Franceschini¹. | ¹Rheumatology and Clinical Immunology Unit, ASST Spedali Civili of Brescia, Brescia, Italy; ²Rheumatology Department, Centro Hospitalar Universitário de Coimbra - ULS Coimbra, Coimbra, Portugal; ³Rheumatology  Department, ULS Aveiro, Aveiro, Portugal; ⁴Department of Clinical and Experimental Sciences, University of Brescia, Brescia, Italy.

  Società Italiana di Reumatologia

  26-11-2025

  https://doi.org/10.4081/reumatismo.2025.2046

  76

• CO:08:5 | Clinical impact of anti-Ro52 antibodies in idiopathic inflammatory myopathies: insights from a multicenter Italian cohort Paola Bizioli¹, Cesare Tomasi², Francesca Bellisai³, Francesca Buzzulini⁴, Antonio Tonutti^5|6, Angela Ceribelli^5|6, Edoardo Conticini³, Anna Ghirardello⁷, Luca Iaccarino⁷, Danilo Villalta⁴, Franco Franceschini¹, Ilaria Cavazzana¹. | ¹Rheumatology and Clinical Immunology Unit - ERN ReCONNET, ASST Spedali Civili of Brescia; ²Department of Clinical and Experimental Sciences, University of Brescia; ³Department of Medicine, Surgery and Neurosciences, Rheumatology Unit, University of Siena; ⁴Department of Laboratory Immunology and Allergology, Santa Maria degli Angeli Hospital, Pordenone; ⁵Department of Biomedical Sciences, Humanitas University, Rozzano (MI); ⁶Rheumatology and Clinical Immunology, Istituti di Ricovero e Cura a Carattere Scientifico, Humanitas Research Hospital, Rozzano (MI); ⁷Division of Rheumatology, Department of Medical and Surgical Sciences, University of Padova, Italy

  Società Italiana di Reumatologia

  26-11-2025

  https://doi.org/10.4081/reumatismo.2025.1984

  71