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PO:02:016 | Real-world evidence of upadacitinib over two years in Italian patients with axial spondyloarthritis Mariagrazia Lorenzin1, Giacomo Cozzi1, Stefano Gentileschi2, Michele Maria Luchetti Gentiloni3, Antonio Carletto4, Maria Sole Chimenti5, Maria Manara6, Luca Quartuccio7, Rosario Foti8, Salvatore D'Angelo9, Ariela Hoxha10, Carlo Selmi11, Bernd Raffeiner12, Alessandro Giollo1, Alberto Cauli13, Carlo Salvarani14, Fabiola Atzeni15, Roberta Ramonda1, Sir Study Group Spa E Psa Antonio Spadaro16. | 1Rheumatology Unit, Department of Medicine DIMED, University of Padova, Padova, Italy; 2Rheumatology Unit, Department of Medicine, Surgery and Neurosciences, University of Siena, Siena, Italy; 3Clinica Medica, Ospedali Riuniti Ancona University Hospital, Ancona; Department of Clinical and Molecular Sciences, Ancona, Italy; 4Rheumatology Unit, Department of Medicine, AOUI University of Verona, Verona, Italy; 5Rheumatology, allergology and clinical Immunology, Department of Systems Medicine, University of Rome Tor Vergata, Roma, Italy; 6Humanitas San Pio X, Milano, Italy; 7University of Udine, Academic Hospital Santa Maria della Misericordia, Udine, Italy; 8Rheumatology Unit, A.O.U. Policlinico S. Marco, Catania, Italy; 9Rheumatology Department of Lucania, San Carlo Hospital of Potenza and Madonna delle Grazie Hospital of Matera, Potenza, Italy; 10Internal Medicine Unit, Thrombotic and Hemorrhagic Center, Department of Medicine-DIMED, University of Padua, Padova, Italy; 11Department of Rheumatology and Clinical Immunology, IRCCS Humanitas Research Hospital, Rozzano, Milano, Italy; 12Department of Rheumatology, Teaching Hospital of the Paracelsius Medical Hospital of Bolzano ASAA-SABES, Bolzano, Italy; 13Rheumatology Unit, Department of Medical Sciences, AOU and University of Cagliari, Monserrato, Cagliari, Italy; 14Department of Rheumatology, Azienda USL-IRCCS di Reggio Emilia and Università di Modena and Reggio Emilia, Reggio Emilia, Italy; 15Rheumatology Unit, University of Messina, Messina, Italy; 16Società Italiana di Reumatologia, Milano, Italy.
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PO:23:046 | Histopathological comparison between minor salivary gland biopsies from pediatric and adult patients with Sjögren’s disease: evidence of a more severe inflammatory profile in early-onset cases Flavia Riccio1, Mattia Neri2, Martina Mellone1, Immacolata Cozzolino3, Jacopo Ferro4, Valerio Gaetano Vellone4, Ciro Emiliano Boschetti5, Giuseppe Colella5, Nicola Laffi6, Pietro Buono7, Enrico Tirri8, Renato Franco3, Marco Gattorno2, Francesco Ciccia1, Clara Malattia2, Saviana Gandolfo8 | 1UOC di Reumatologia, Università degli Studi della Campania Luigi Vanvitelli, Napoli; 2UOC di Reumatologia e Malattie Autoinfiammatorie, Istituto Giannina Gaslini, Genova; 3UO di Anatomia Patologica, Università degli Studi della Campania Luigi Vanvitelli, Napoli; 4UOC di Anatomia Patologica, Istituto Giannina Gaslini Genova; 5UOC di Chirurgia Maxillo-facciale, Università degli Studi della Campania Luigi Vanvitelli, Napoli; 6UO di Odontoiatria, Istituto Giannina Gaslini, Genova; 7UOD Attività consultoriali e assistenza materno-infantile, Direttorato Generale per la Salute, Regione Campania, Napoli; 8UO di Reumatologia, Ospedale del Mare, Napoli, Italy
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PO:06:089 | Heat-not-burn cigarettes induce protein post-translational modifications (PTM): possible role in the pathogenesis of rheumatoid arthritis Claudia Ciancarella1, Federica Maria Ucci1, Valeria Manganelli2, Elena Fasciolo2, Roberta Priori1, Fulvia Ceccarelli1, Manuel Sergi3, Camilla Montesano3, Francesco Bartolini3, Maurizio Sorice2, Cristiano Alessandri1, Fabrizio Conti1 | 1Rheumatology Unit, Department of Internal Medicine, Anesthesiology and Cardiovascular Sciences, La Sapienza, Roma, Italy; 2Department of Experimental Medicine, La Sapienza University of Rome, Italy; 3Department of Chemistry, La Sapienza University Of Rome, Italy
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PO:06:093 | Clinical and ultrasound phenotyping comparison between Difficult-To-Treat Rheumatoid Arthritis (D2TRA) and non-D2TRA patients: experience from a monocentric cohort Silvia Perrone1, Claudio Cruciani1, Silvia Mascolo1, Elisa Bellis1, Gloria Crepaldi1, Valeria Data1, Claudia Garulli1, Claudia Lomater1, Elena Marucco1, Marta Saracco1, Mariele Gatto1, Annamaria Iagnocco1. | 1Academic Rheumatology Centre, Department of Clinical and Biological Sciences, University of Turin, AO Mauriziano, Turin, Italy.
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PO:36:246 | Early real-world outcomes with benralizumab in eosinophilic granulomatosis with polyangiitis: a monocentric retrospective Richard Borrelli1, Stefania Nicola1, Federica Corradi1, Iuliana Badiu1, Marzia Boem1, Valentina Marmora1, Simone Negrini1, Luisa Brussino1. | 1SCDU Immunologia e Allergologia, AO Mauriziano, Dipartimento di Scienze Mediche, Università degli Studi di Torino, Torino, Italy.
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CO:01:1 | Efficacy and safety of rituximab across the four phenotypes of IgG4-related disease: a European multi-center cohort study of 115 patients Marco Lanzillotta1, Jens Vikse2, Elisabetta Goni3, Veronica Batani1, Jasmin Mahajne1, Lorenzo Dagna1, Emanuel Della Torre1. | 1Unit of Immunology, Rheumatology, Allergy, and Rare Disease, IRCCS Ospedale San Raffaele, Milano, Italy; 2Department of Rheumatology, Stavanger University Hospital, Norway; 3Department of Medicine II, University Hospital, Ludwig Maximilian University, Munich, Germany
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PO:35:234 | Sustained Vasculitis Quiescence and CS Reduction with Mepolizumab 100 mg Francesca Mascia1, Angelo Fassio2, Marco Zurlo1, Davide Chesini3, Francesco Pollastri2, Giovanni Adami2, Davide Gatti4, Maurizio Rossini4, Matteo Maule5, Gianentrico Senna1, Marco Caminati1 | 1University of Verona - Allergology and Clinical Immunology Verona, Italy; 2Policlinico G. B. Rossi - Rheumatology Verona, Italy; 3University of Verona - Faculty of Medicine and Surgery Verona, Italy; 4University of Verona - Rheumatology Verona, Italy; 5Policlinico G. B. Rossi - Allergology and Clinical Immunology Verona, Italy
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PO:16:232 | Belimumab step-down dose spacing in patients with systemic lupus erythematosus in persistent clinical remission: experience from a multicentric cohort Alice Bartoletti1, Laura Giudice1, Lorenza Maria Argolini1|2, Giuseppe Alvise Ramirez3, Luca Moroni3, Tommaso Schioppo4, Chiara Bellocchi5|6, Annalaura Fasiello6, Lorenzo Beretta6, Lorenzo Dagna3, Roberto Caporali1, Maria Gerosa1. | 1UO Clinica Reumatologica, ASST Gaetano Pini CTO, Milano, Italy; 2UOC Medicina fisica e riabilitazione specialistica, ASST Gaetano Pini CTO, Milano, Italy; 3Unit of Immunology, Rheumatology, Allergy and Rare Diseases, IRCCS San Raffaele Hospital, Vita-Salute San Raffa Milano Italy; 4Medicina Generale II, Servizio di Reumatologia, Ospedale San Paolo, ASST Santi Paolo Carlo, Milano, Italy; 5Department of Clinical Sciences and Community Health, University of Milan, Dipartimeto di Eccellenza 2023-2027, Milano, Italy; 6Referral Centre for Systemic Autoimmune DIseases, Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico, Milano, Italy
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PO:07:099 | Survival on therapy of certolizumab pegol in rheumatoid arthritis, psoriatic arthritis, and spondyloarthritis: 8-year data from an Italian multicenter register Maria Manara1, Gilberto Cincinelli1|2, Marco Fornaro3, Simone Perniola4, Elisa Gremese5, Chiara Bazzani6, Serena Bugatti7, Francesca Romana Spinelli8, Rosario Foti9, Marco Sebastiani10, Alberto Cauli11, Fabiola Atzeni12, Giovanni Lapadula13, Gianfranco Ferraccioli14, Fabrizio Conti8, Florenzo Iannone3, Roberto Caporali1|2 | 1Department of Rheumatology and Medical Sciences, ASST G. Pini-CTO Milano; 2Department of Clinical Sciences and Community Health, University of Milan; 3Department of Precision and Regenerative Medicine and Ionian Area, University of Bari; 4Clinical Immunology Division, Fondazione Policlinico Universitario A. Gemelli IRCCS, Roma; 5Rheumatology and Clinical Immunology, IRCCS Humanitas Research Hospital, Rozzano (MI); 6Unit of Rheumatology and Clinical Immunology, ASST Spedali Civili Brescia; 7Department of Internal Medicine and Therapeutics, Università di Pavia; 8Rheumatology Unit, Dipartimento Scienze Cliniche Internistiche, Anestesiologiche e Cardiovascolari, Sapienza University, Roma; 9Rheumatology Unit, San Marco Hospital, Policlinico University of Catania; 10Rheumatology Unit, AUSL Piacenza, University of Parma; 11UOC di Reumatologia, Dipartimento di Scienze Mediche e Sanità Pubblica, Azienda Ospedaliero-Universitaria di Cagliari; 12Rheumatology Unit, Department of Experimental and Internal Medicine, University of Messina; 13Gruppo Italiano di Studio sulla Early Arthritis, GISEA, Bari; 14Department of Medicine, Università Cattolica del Sacro Cuore, Fondazione IRCCS Policlinico Gemelli, Roma, Italy
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CO:06:3 | Clinical and laboratory markers for distinguishing VEXAS from Schnitzler's syndrome in male patients with skin involvement: insights from the International AIDA Network Registries Valeria Caggiano1, Jessica Sbalchiero1, Micol Frassi2, Andrea Hinojosa-Azaola3, Francesca Crisafulli2, Franco Franceschini2, Paolo Sfriso4, Sara Bindoli4, José Hernández-Rodríguez5, Henrique A. Mayrink Giardini6, Giuseppe Lopalco7, Florenzo Iannone7, Ombretta Viapiana8, Amato De Paulis9, Lorenzo Dagna10, Antonio Gidaro11, Serena Bugatti12, Matteo Piga13, Fabrizio Conti14, Rosetta Vitetta15, Cecilia Chighizola16, Marcello Govoni17, Giacomo Emmi18, Paola Triggianese19, Carmelo Gurnari19, Bruno Frediani1, Claudia Fabiani1, Luca Cantarini1, Antonio Vitale1, for the AIDA Network1 | 1Department of Medical Sciences, Surgery and Neurosciences, University of Siena; 2University of Brescia, Italy; 3Department of Immunology and Rheumatology, Mexico City, Mexico; 4Rheumatology Unit, University of Padova, Italy; 5Clinical Unit of Autoinflammatory Diseases, Hospital Clínic of Barcelona, Spain; 6Rheumatology Division, Universidade de São Paulo, Brazil; 7University of Bari; 8Rheumatology Unit, University and Azienda Ospedaliera Universitaria Integrata of Verona; 9University of Napoli "Federico II"; 10Università Vita-Salute San Raffaele, Milano; 11Luigi Sacco Hospital, University of Milano; 12Università di Pavia; 13University and AOU of Cagliari; 14AOU Policlinico Umberto I, Sapienza University of Rome; 15Unit of Rheumatology, ASL Sant' Andrea Hospital, Vercelli; 16University of Milano; 17Azienda Ospedaliero-Universitaria S. Anna, Ferrara; 18University of Trieste; 19University of Rome-Tor Vergata, Rome, Italy.
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PO:36:252 | Long-Term Outcomes of Patients with Takayasu Arteritis in the Era of Biological Agents: a Multicenter International Study Alessandro Tomelleri1, Durga Prasanna Misra2, Fatma Alibaz-Oner3, Chiara Marvisi4, Chiara Calabrese1, Upendra Rathore2, Aysegul Avcu3, Adele Del Giudice4, Elisabetta Olivi4, Caterina Ricordi4, Corrado Campochiaro1, Elena Baldissera1, Marco Matucci-Cerinic1, Haner Direskeneli3, Carlo Salvarani4, Lorenzo Dagna1 | 1IRCCS Ospedale San Raffaele, Unità di Immunologia, Reumatologia, Allergologia e Malattie Rare Milano, Italy; 2Sanjay Gandhi Postgraduate Institute of Medical Sciences SGPGIMS, Clinical Immunology and Rheumatology Lucknow Country, India; 3Marmara University, School of Medicine, Department of Internal Medicine, Division of Rheumatology Istanbul, Turkey; 4Azienda USL-IRCCS di Reggio Emilia, Unità di Reumatologia Reggio Emilia, Italy
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PO:20:002 | Respiratory function tests predict bone mineral density in autoimmune rheumatic disease patients Andrea Zoli1, Panagiotis Garantziotis2, Sebastian Böltz2, Janina Auth2, Sara Bayat2, Jule Taubmann2, Anna-Maria Liphardt2, Maria Antonietta D'Agostino1, Christina Bergmann2, Georg Schett2. | 1Division of Rheumatology, Fondazione Policlinico Universitario A. Gemelli, IRCCS, Università Cattolica del Sacro Cuore, Roma, Italy; 2Department of Medicine 3, Rheumatology and Immunology, Friedrich Alexander Universität FAU, Erlangen, Germany.
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PO:18:268 | Voclosporin as a Steroid-Sparing Agent in Lupus Nephritis Complicated by Central Serous Chorioretinopathy: A Case Report Irene Genovali1|2, Sebastiano Lorusso2, Damiano Currado1|2, Letizia Pia Di Corcia1, Ludovica Lamberti1, Annalisa Marino2, Antonio Orlando1, Maria Quadrini1, Marta Vadacca2, Marta Vomero1, Luca Navarini1|2, Roberto Giacomelli1|2 | 1Rheumatology and Clinical Immunology, Department of Medicine, University of Rome Campus Biomedico, School of Medicine Rome, Italy; 2Clinical and Research Section of Rheumatology and Clinical Immunology Fondazione Policlinico Campus Biomedico Rome, Italy
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CO:08:5 | Clinical impact of anti-Ro52 antibodies in idiopathic inflammatory myopathies: insights from a multicenter Italian cohort Paola Bizioli1, Cesare Tomasi2, Francesca Bellisai3, Francesca Buzzulini4, Antonio Tonutti5|6, Angela Ceribelli5|6, Edoardo Conticini3, Anna Ghirardello7, Luca Iaccarino7, Danilo Villalta4, Franco Franceschini1, Ilaria Cavazzana1. | 1Rheumatology and Clinical Immunology Unit - ERN ReCONNET, ASST Spedali Civili of Brescia; 2Department of Clinical and Experimental Sciences, University of Brescia; 3Department of Medicine, Surgery and Neurosciences, Rheumatology Unit, University of Siena; 4Department of Laboratory Immunology and Allergology, Santa Maria degli Angeli Hospital, Pordenone; 5Department of Biomedical Sciences, Humanitas University, Rozzano (MI); 6Rheumatology and Clinical Immunology, Istituti di Ricovero e Cura a Carattere Scientifico, Humanitas Research Hospital, Rozzano (MI); 7Division of Rheumatology, Department of Medical and Surgical Sciences, University of Padova, Italy
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PO:05:066 | Atypical diagnosis and manifestation of spondyloarthritis: a case report Adele Del Giudice1, Filippo Crescentini2, Giorgia Citriniti2, Luca Cimino1|3, Carlo Salvarani1|2 | 1Department of Rheumatology, Università Cattolica del Sacro Cuore, Fondazione Policlinico Universitario A. Gemelli IRCCS, Roma, Italy; 2Department of Medicine, University of Melbourne at St Vincent's Hospital Melbourne, Australia; 3Department of Rheumatology, Division of Medicine, University College, London, UK
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CO:10:4 | Lung vasculature quantification on computed tomography predicts new onset of interstitial lung disease in systemic sclerosis Maria Iacovantuono1|2, Nicholas Landini2|3, Lisa Jungblut4, Gesa Sauer2, Rucsandra Dobrota2, Maria Sinziana Muraru-Carbune2, Muriel Elhai2, Carmen-Marina Mihai2, Mike Oliver Becker2, Maria Sole Chimenti1, Thomas Frauenfelder4, Anna-Maria Hoffmann-Vold5, Oliver Distler2, Cosimo Bruni2. | 1Rheumatology, Allergology and Clinical Immunology, Department of Systems Medicine, Tor Vergata University, Rome, Italy; 2Department of Rheumatology, University Hospital Zurich, University of Zurich, Switzerland; 3Department of Radiological Sciences, Oncology and Pathology, Sapienza University, Policlinico Umberto I, Rome, Italy; 4Institute for Diagnostic and Interventional Radiology, University Hospital Zurich, University Zurich, Switzerland; 5Department of Rheumatology, Oslo University Hospital, Norway
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PO:25:083 | Overlap between Sjögren’s syndrome and lichen sclerosus: beyond coincidence? Emanuele Giovanni Grilli1, Ludovica Manisera1, Ilenia Fischetti1, Linda Mastromanno1, Martina Villa1, Angelica Gattamelata1, Fabrizio Conti1, Roberta Priori1|2, Serena Colafrancesco3|4 | 1Dipartimento di Medicina e Chirurgia, Università Milano-Bicocca; 2U.O. Reumatologia, IRCCS Fondazione San Gerardo dei Tintori, Monza; 3U.O. Pneumologia, IRCCS Fondazione San Gerardo dei Tintori, Monza; 4Rheumatology and Clinical Immunology, Istituto di Ricovero e Cura a Carattere Scientifico, IRCCS Humanitas Research Hosp, Rozzano, Milano, Italy
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PO:01:003 | Sex-based differences in 2 years treatment outcomes with b/ts-DMARDs in psoriatic arthritis: from real-world evidence to predictive modeling from the Gruppo Italiano Studio Early Arthritis (GISEA) prospective registry Simone Perniola1, Florenzo Iannone1, Francesco Paolo Cantatore2, Angelo Semeraro3, Leonardo Santo4, Roberto Gorla5, Alberto Cauli6, Roberto Felice Caporali7, Bruno Frediani8, Rosario Foti9, Fabrizio Conti10, Marco Sebastiani11, Maria Sole Chimenti12, Roberta Ramonda13, Fabiola Atzeni14, Maurizio Rossini15, Serena Bugatti16, Serena Guiducci17, Giovanni Lapadula1, Gianfranco Ferraccioli18, Francesca Romana Spinelli10, Elisa Gremese19. | 1Rheumatology Unit, DiMePReJ, University of Bari, Bari; 2Rheumatology Unit, Department of Medical and Surgical Sciences, Azienda Ospedaliero-Universitaria Policlinico Riuniti, Foggia; 3Rheumatology Unit, Martina Franca Hospital; 4Rheumatology Unit, ASL BT, P.O. Barletta; 5Rheumatology and Clinical Immunology Unit, ASST Spedali Civili of Brescia; 6Rheumatology Unit, Department of Medical Science and Public Health, University of Cagliari, Monserrato (CA); 7Rheumatology Unit, Dipartimento di Reumatologia e Scienze Mediche, ASST PINI-CTO, University of Milano, Milano; 8Rheumatology Unit, Azienda Ospedaliero Universitaria Senese, Siena; 9Rheumatology Unit, A.O.U. Policlinico S. Marco, Catania; 10Rheumatology Unit, Department of Clinical Internal, Anesthesiologic and CV Sciences, Sapienza University of Rome, Roma; 11Rheumatology Unit, AUSL Piacenza, University of Parma, Parma; 12Rheumatology, Department of Systems Medicine, University of Rome Tor Vergata, Roma; 13Rheumatology Unit, DIMED, University of Padua, Padova; 14Rheumatology Unit, Department of Experimental and Internal Medicine, University of Messina, Messina; 15Rheumatology Unit, Department of Medicine, University of Verona, Verona; 16Division of Rheumatology, Dept. of Internal Medicine and Therapy, Fondazione IRCCS Policlinico S. Matteo, University of Pavia, Pavia; 17Division of Rheumatology, Department of Experimental and Clinical Medicine, University of Firenze, Firenze; 18Department of Medicine, Catholic University of the Sacred Heart, Fondazione Policlinico Gemelli IRCCS, Roma; 19Rheumatology and Clinical Immunology, IRCCS Humanitas Research Hospital, Humanitas University, Rozzano (MI), Italy
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PO:31:174 | Increased frequency of anti-RNA polymerase 3 antibodies in patients with systemic sclerosis and silicone breast implants: a multicentre study from the international European Scleroderma Trials and Research cohort Maria Grazia Lazzaroni1, Yolanda Braun-Moscovici2, Elda Piovani1, Claudia Barison1, Liala Moschetti1, Veronica Batani3, Corrado Campochiaro3, Michal Tomcik4, Francesca Motta5, Maria De Santis5, Petros P. Sfikaki6, Masataka Kuwana7, Brigitte Granel8, Roberta Foti9, Virginia Berlingiero10, Joana Caetano11, Yannick Allanore12, Alexandra Balbir-Gurman2, Marco Matucci Cerinic3, Franco Franceschini1, Paolo Airò1. | 1ASST Spedali Civili of Brescia, University of Brescia, Brescia, Italy; 2Rambam Health Care Campus, Rappaport Faculty of Medicine, Technion-Israeli Institute of Tecnology, Haifa, Israel; 3Vita-Salute San Raffaele University, San Raffaele Hospital, Milano, Italy; 4Institute of Rheumatology, Praga, Czech Republic; 5IRCCS Humanitas Research Hospital; Humanitas University, Milano, Italy; 6Joint Rheumatology Program, Medical School, National Kapodistrian University of Athens Atene GREECE; 7Nippon Medical School Hospital Tokyo Japan; 8Hôpital Nord de Marseille; Aix-Marseille Université Marsiglia France; 9AOU Policlinico G. Rodolico San Marco, Catania, Italy; 10Azienda Ospedaliera Universitaria Senese, Siena, Italy; 11Fernando Fonseca Hospital, Amadora, Portugal; 12Université Paris Cité, Cochin Hospital, Parigi, France.
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