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Reumatismo - The Italian Journal of Rheumatology

Editor-in-Chief: M.A. Cimmino, Genova, Italy | eISSN 2240-2683

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  • CO:01:2 | BAG3 in systemic sclerosis: possible therapeutic target and biomarker for pulmonary fibrosis Claudia Iannone1|2, Margot De Marco3, Antonina Minniti1, Paola Manzo3, Angela D'Ardia3, Antonia Falco3, Liberato Marzullo3, Angela Rosato3, Maria Caterina Turco3, Roberto Caporali1|2, Nicoletta Del Papa1|2. | 1ASST G. Pini-CTO. UOC Clinica Reumatologica, Milano; 2Department of Clinical Sciences and Community Health, University of Milano; 3Department of Medicine, Surgery and Dentistry Schola Medica Salernitana, Baronissi (SA), Italy

    Società Italiana di Reumatologia
    25-11-2025
    https://doi.org/10.4081/reumatismo.2025.1962
    290
  • Insight into the WNT system and its drug related response

    S. Tamanini, L. Idolazzi, D. Gatti, O. Viapiana, A. Fassio, M. Rossini
    219-230
    18-12-2013
    https://doi.org/10.4081/reumatismo.2013.219
    3285
    PDF: 1229
  • LABORATORY FINDINGS IN PSORIATIC ARTHRITIS

    L. Punzi, M. Poswiadek, F. Oliviero, A. Lonigro, V. Modesti, R. Ramonda, S. Todesco
    52-55
    https://doi.org/10.4081/reumatismo.2007.1s.52
    2629
    PDF: 1610
  • MicroRNAs in autoimmune rheumatic diseases

    M. Galeazzi, E. Balistreri, C. Giannitti, G.D. Sebastiani
    7-17
    16-03-2012
    https://doi.org/10.4081/reumatismo.2012.7
    1062
    PDF: 976
  • PO:08:113 | Shaping rheumatoid arthritis treatment: clinical and demographic drivers of tsDMARDs versus bDMARDs prescription post-EMA pronouncement on JAK inhibitors - insights from the AMBI-RA study Riccardo Bertola1, Beatrice Maranini1, Carlo Garaffoni1, Maria Pozzuto1, Anna Laura Riva Cambrino1, Alessandro Spinelli1, Letizia Mamprin1, Federico Agostini1, Martina Di Nunzio1, Marcello Govoni1, Alessandra Bortoluzzi1, Ettore Silvagni1 | 1Rheumatology Unit, Department of Medical Sciences, University of Ferrara and Azienda Ospedaliero-Universitaria S. Anna, Italy

    Società Italiana di Reumatologia
    25-11-2025
    https://doi.org/10.4081/reumatismo.2025.2139
    216
  • Metabolism plays the key roles in Th cells differentiation

    A. Hosseinzadeh, S. Soukhtehzari, M. Ghaedi, R. Mansouri
    176-182
    31-12-2016
    https://doi.org/10.4081/reumatismo.2016.919
    1778
    PDF: 1181
  • PO:01:014 | Differential inflammatory responses of CD14+ and CD14– synoviocytes in psoriatic arthritis: implications for pathogenesis and targeted therapies Monia Maccaferri1, Monica Montanari2, Francesco Zambianchi3|4, Carlo Salvarani1|5, Elisa Pignatti1|4 | 1Dipartimento CHIMOMO; 2Dipartimento di Scienze e Vita; 3Dipartimento SMECHIMAI Università di Modena e Reggio Emilia; 4Azienda Ospedaliero Universitaria di Modena; 5Struttura Complessa di Reumatologia, Azienda Unità Sanitaria Locale di Reggio Emilia-IRCCS, Italy

    Società Italiana di Reumatologia
    25-11-2025
    https://doi.org/10.4081/reumatismo.2025.2123
    177
  • The pink side of spondyloarthritis: a narrative review across pathogenesis and clinical manifestations in women

    C. Rizzo, L. La Barbera, A. D’Antonio, F. Camarda, P. Conigliaro, M.S. Chimenti, G. Guggino
    11-09-2024
    https://doi.org/10.4081/reumatismo.2024.1764
    1462
    PDF: 464
  • Rapid effectiveness of certolizumab pegol in non-radiographic axial spondyloarthritis

    A. Spadaro, A. Scarno, A. Carboni, F.M. Perrotta, C. Catalano, E. Lubrano, G. Valesini
    134-137
    24-07-2013
    https://doi.org/10.4081/reumatismo.2013.134
    2902
    PDF: 857
  • CTLA4-Ig interferes and downregulates the proinflammatory activities of rheumatoid synovial macrophages in monoculture

    R. Brizzolara, S. Soldano, P. Montagna, A. Sulli, B. Seriolo, B. Villaggio, P.F. Triolo, P. Clerico, L. Felli, L. Molfetta, M. Cutolo
    80-85
    https://doi.org/10.4081/reumatismo.2011.80
    1673
    PDF: 1120
  • Wegener’s granulomatosis: an analysis of 50 patients

    G. Di Comite, G. Bonavida, E. Bozzolo, S. Bozzolo, S. Bianchi, G. Ciboddo, M. Tresoldi, L. Praderio, M.G. Sabbadini
    187-192
    11-04-2005
    https://doi.org/10.4081/reumatismo.2005.187
    944
    PDF: 1626
  • Successful treatment of refractory adult onset Still’s disease with rituximab

    N. Belfeki, M. Smiti Khanfir, F. Said, A. Hamzaoui, T. Ben Salem, I. Ben Ghorbel, M. Lamloum, M.H. Houman
    159-162
    16-12-2016
    https://doi.org/10.4081/reumatismo.2016.888
    3075
    PDF: 1393
  • Pain assessment strategies in patients with musculoskeletal conditions

    F. Salaffi, A. Ciapetti, M. Carotti
    216-229
    28-09-2012
    https://doi.org/10.4081/reumatismo.2012.216
    3085
    PDF: 3367
  • TNFa inhibition in anti-Ro/SSA positive patients with rheumatoid arthritis: clinical and immunological effects

    I. Cavazzana, F. Bobbio-Pallavicini, C. Bazzani, E. Bravi, S. Zingarelli, A. Ceribelli, R. Caporali, R. Cattaneo, F. Franceschini, C. Montecucco
    275-282
    https://doi.org/10.4081/reumatismo.2006.275
    1259
    PDF: 1025
  • PO:07:103 | Tocilizumab use in patients with rheumatoid arthritis and malignancy: a monocentric experience Vittorio Dibenedetto1|2|3, Nicola Farina1|2, Nicola Boffini1|2, Alessandro Tomelleri1|2, Adriana Cariddi1|2, Elena Baldissera1|2, Marco Matucci-Cerinic1|2|3, Lorenzo Dagna1|2|3. | 1Unit of Immunology, Rheumatology, Allergy and Rare Diseases, IRCCS San Raffaele Hospital, Milano, Italy; 2Inflammation, Fibrosis and Ageing Intitiative INFLAGE, IRCCS San Raffaele Hospital, Milano, Italy; 3Vita-Salute San Raffaele University, Milano, Italy.

    Società Italiana di Reumatologia
    25-11-2025
    https://doi.org/10.4081/reumatismo.2025.2021
    195
  • CO:12:1 | Inside the Heterogeneity of Primary Central Nervous System Vasculitis: A single-centre 40-year experience Carlo Salvarani1, Gene G Hunder2, Caterina Giannini2, Teresa Jh Christianson2, Robert D Brown2 | 1Azienda USL-IRCCS di Reggio Emilia e UNIMORE Reggio Emilia, Italy; 2Mayo Clinic Rochester, USA

    Società Italiana di Reumatologia
    18-03-2026
    https://doi.org/10.4081/reumatismo.2025.2279
    31
  • Methylenetetrahydrofolate reductase polymorphisms in methotrexate treatment of rheumatoid arthritis patients. Review of the literature and personal experience

    M. Taraborelli, L. Andreoli, S. Archetti, M. Ferrari, R. Cattaneo, A. Tincani
    98-106
    https://doi.org/10.4081/reumatismo.2009.98
    1373
    PDF: 1298
  • Granulomatosis polyangiitis associated with meningeal involvement: response to rituximab therapy after failure of cyclophosphamide

    M. Benucci, F. Li Gobbi, P. Panconesi, M. Manfredi, P. Sarzi-Puttini, F. Atzeni
    90-94
    27-05-2013
    https://doi.org/10.4081/reumatismo.2013.90
    3390
    PDF: 994
  • Stress response system and personality in rheumatoid arthritis patients

    C. Prete, F. Briano, C. Pizzorni, A. Sulli, M. Marcenaro, M. Cutolo
    204-209
    https://doi.org/10.4081/reumatismo.2001.204
    1581
    PDF: 969
  • PO:37:260 | Mepolizumab in the treatment of patients with eosinophilic granulomatosis with polyangiitis: real-life experience from a single-center cohort Eleonora Bruschi1, Fabrizio Angeli1, Alessandro Belotti Masserini1, Stefania Bertocchi1, Silvia Breda1, Elide Lupi1, Valeria Rossi1, Tania Ubiali1, Massimiliano Limonta1 | 1ASST Papa Giovanni XXIII Bergamo Italy

    Società Italiana di Reumatologia
    25-11-2025
    https://doi.org/10.4081/reumatismo.2025.2220
    176
  • The role of leukemia inhibitory factor in autoimmune disorders: insights into recovery and treatment

    Zahra Rodgarpoor, Ahmad Meshkin, Mohammadamin Ehramianpour, Fateme Zare
    01-04-2025
    https://doi.org/10.4081/reumatismo.2025.1753
    1906
    PDF: 177
  • Early rheumatoid arthritis: a prospective study on how to induce the remission

    T. Ziglioli, C. Bazzani, M. Filippini, S. Zingarelli, A. Giugno, R. Gorla
    131-135
    https://doi.org/10.4081/reumatismo.2008.131
    1180
    PDF: 804
  • Multisystemic inflammatory syndrome related to COVID-19, with latent tuberculosis in bone marrow, and satisfactory response to tocilizumab, in a 7-year-old boy

    Z. Morel, R. Suarez, E. Avalos, S. Velázquez, F. Martínez, V. Lezcano, N. Astigarraga, C. Ghezzi, S. Brizuela, G. Samudio
    07-02-2022
    https://doi.org/10.4081/reumatismo.2021.1448
    6527
    PDF: 887
  • Ultrasonographic assessment of the response to Etanercept treatment in patients with rheumatoid arthritis

    A. Iagnocco, C. Perella, F. Ceccarelli, E. Tripodo, C. Alessandri, L. Magrini, G. Valesini
    233-238
    https://doi.org/10.4081/reumatismo.2006.233
    1150
    PDF: 1082
  • Effects of mannuronic acid (M2000) on gene expression profile of signal transducer and activator of transcription proteins (STATs) in rheumatoid arthritis patients

    N.A.G. Gaafar, M. Aslani, Z. Aghazadeh, S.S. Mortazavi-Jahromi, A. Razavi, A. Mirshafiey
    93-102
    23-07-2020
    https://doi.org/10.4081/reumatismo.2020.1235
    1253
    PDF: 816
  • Study on the possible role of the -174G>C IL-6 promoter polymorphism in predicting response to rituximab in rheumatoid arthritis

    M. Fabris, L. Quartuccio, S. Lombardi, M. Benucci, M. Manfredi, M. Saracco, F. Atzeni, P. Morassi, M.A. Cimmino, E. Pontarini, C. Fabro, R. Pellerito, P. Sarzi-Puttini, M. Cutolo, A. Carletto, L.M. Bambara, F. Fischetti, F. Curcio, E. Tonutti, S. De VIta
    253-258
    https://doi.org/10.4081/reumatismo.2010.253
    2415
    PDF: 923
  • Effects of estrogen peripheral metabolism in rheumatoid arthritis

    S. Capellino, P. Montagna, B. Villaggio, M. Cutolo
    78-82
    https://doi.org/10.4081/reumatismo.2005.78
    1603
    PDF: 2001
  • PO:11:171 | Subcutaneous tocilizumab use in a young-onset mixed connective tissue disease patient with multiple treatment failures Rhaysa Araujo Mousinho1, Elide Lupi2, Massimiliano Limonta2 | 1Clinica di Reumatologia, Dipartimento di Medicina and 2Istituto di Anatomia Patologica, Dipartimento di Medicina di Laboratorio, Osp. S. M. della Misericordia, Università di Udine, Italy

    Società Italiana di Reumatologia
    25-11-2025
    https://doi.org/10.4081/reumatismo.2025.2154
    194
  • Brachio-cervical inflammatory myopathy associated with systemic sclerosis. Case series and review of literature

    C.S.R. Araujo, R. Miossi, F.H.C. De Souza, M.D. Costa, A.M.S. da Silva, E.D. Campos, E. Zanoteli, S.K. Shinjo
    122-130
    03-08-2021
    https://doi.org/10.4081/reumatismo.2021.1397
    3957
    PDF: 1112
  • PO:23:052 | Muscular and myocardial involvement in antisynthetase syndrome: a retrospective real-life study Giulia Buonsante1|2|3, Giacomo De Luca1|2|3, Veronica Batani1|2, Daniele Scaramuzzi1|2|3, Lorenzo Dagna1|2|3, Marco Matucci-Cerinic1|2|3, Corrado Campochiaro1|2|3. | 1Unit of Immunology, Rheumatology, Allergy and Rare Diseases UNIRAR, IRCCS San Raffaele Hospital, Milano, Italy; 2Inflammation, Fibrosis and aging Initiative INFLAGE, IRCCS San Raffaele Hospital, Milano, Italy; 3Vita-Salute San Raffaele University, Milan, Italy, Milano, Italy.

    Società Italiana di Reumatologia
    25-11-2025
    https://doi.org/10.4081/reumatismo.2025.2056
    195
  • A comparison between the Simplified Disease Activity Index (SDAI) and the Disease Activity Score (DAS28) as measure of response to treatment in patients undergoing different therapeutic regimens

    Giovanna Cuomo, Gabriella Molinaro, Giovanni La Montagna, Sergio Migliaresi, Gabriele Valentini
    22-25
    https://doi.org/10.4081/reumatismo.2006.22
    1711
    PDF: 2099
  • PO:04:061 | Higher prevalence of baseline comorbidities in patients developing difficult to treat psoriatic arthritis Mario Ferraioli1, Michelina Turri1, Eneida Çela1, Mauro Fatica1, Paola Conigliaro1, Elisabetta Greco1, Alberto Bergamini1, Maria Sole Chimenti1. | 1Rheumatology, Allergology and Clinical Immunology, Department of Systems Medicine, University of Rome, Tor Vergata, Rome, Italy.

    Società Italiana di Reumatologia
    25-11-2025
    https://doi.org/10.4081/reumatismo.2025.2011
    158
  • PO:29:139 | Modulation of autonomic dysfunction in fibromyalgia through auricular vagal nerve stimulation: preliminary results Sonia Farah1, Marco Di Carlo1, Maria Giovanna Lommano1, Benedetta Bianchi1, Piercarlo Sarzi Puttini2, Fausto Salaffi1. | 1Rheumatology Clinic, Università Politecnica delle Marche, Ospedale Carlo Urbani, Jesi, Italy; 2Rheumatology Unit, IRCCS Galeazzi-Sant Ambrogio Hospital, Milano State University School of Medicine, Milano, Italy.

    Società Italiana di Reumatologia
    25-11-2025
    https://doi.org/10.4081/reumatismo.2025.2067
    200
  • PO:06:081 | Safety of JAK inhibitors compared to non-TNF-targeted biologic therapies in rheumatoid arthritis patients who are inadequate responders to TNF inhibitors Lorenzo Di Luozzo1, Alessandro Giollo1, Mariangela Salvato1, Francesca Frizzera1, Kiren Khalid1, Margherita Zen1, Andrea Doria1 | 1Azienda ospedaliera universitaria di Padova, unità di Reumatologia, Padova, Italy

    Società Italiana di Reumatologia
    18-03-2026
    https://doi.org/10.4081/reumatismo.2025.2298
    68
  • Efficacy and safety of anti-TNF agents in the Lombardy rheumatoid arthritis network (LORHEN)

    P. Sarzi- Puttini, M. Antivalle, A. Marchesoni, E.G. Favalli, R. Gorla, M. Filippini, R. Caporali, F. Bobbio-Pallavicini, C. Montecucco, F. Atzeni
    290-295
    https://doi.org/10.4081/reumatismo.2008.290
    2319
    PDF: 1179
  • Autologus peripheral stem cell transplantation in a patient with diffuse systemic sclerosis: our experience

    F. Giorgetti, M.L. Minnucci, P. Santori, L. Ercoli, M. Rossi, M. Del Papa, G. Morico, P. Squadroni, A. Olivieri, R. Centurioni
    51-56
    https://doi.org/10.4081/reumatismo.2004.51
    1328
    PDF: 1205
  • CO:09:1 | The impact of sex and gender on fibromyalgia syndrome: data from the Italian Fibromyalgia Registry Martina Favretti1, Cristina Iannuccelli2, Giulio Dolcini1, Sonia Farah3, Marco Di Carlo3, Giuseppina Tramontano4, Giorgia Ferrari4, Fabiola Atzeni5, Greta Pellegrino6|7, Piercarlo Sarzi-Puttini6|7, Fausto Salaffi3, Manuela Di Franco8. | 1Dipartimento di Medicina Molecolare, Sapienza Università di Roma; 2UOC Reumatologia, Policlinico Umberto I, Roma; 3Unità di Reumatologia, Dipartimento di Scienze Cliniche e Molecolari, Università Politecnica delle Marche, Jesi (AN); 4Unità di Reumatologia, Dipartimento di Specialità Mediche, Regional Health Trust 3, Genova; 5Unità di Reumatologia, Dipartimento di Medicina Interna, Università di Messina; 6Unità di Reumatologia, IRCCS Ospedale Galeazzi - Sant'Ambrogio, Milano; 7Dipartimento di Scienze Biomediche e Cliniche, Università degli studi di Milano; 8UOC Reumatologia, Dipartimento di Scienze Cliniche Internistiche Anestesiologiche e Cardiovascolari, La Sapienza, Roma, Italy

    Società Italiana di Reumatologia
    25-11-2025
    https://doi.org/10.4081/reumatismo.2025.1986
    220
  • Anti-tumor necrosis factor α: originators versus biosimilars, comparison in clinical response assessment in a multicenter cohort of patients with inflammatory arthropathies

    C. Gioia, A. Picchianti Diamanti, R. Perricone, M.S. Chimenti, A. Afeltra, L. Navarini, A. Migliore, U. Massafra, V. Bruzzese, P. Scolieri, C. Meschini, M. Paroli, R. Caccavale, P. Scapato, R. Scrivo, F. Conti, B. Laganà, M. Di Franco
    19-12-2023
    https://doi.org/10.4081/reumatismo.2023.1602
    2225
    PDF: 557
  • Synoviocyte cultures from synovial fluid

    A. Scanu, F. Oliviero, L. Braghetto, R. Ramonda, R. Luisetto, F. Calabrese, A. Pozzuoli, L. Punzi
    66-70
    https://doi.org/10.4081/reumatismo.2007.66
    1935
    PDF: 1176
  • PO:29:138 | Cetylated fatty acids and fibromyalgia: efficacy and tolerability in a prospective study Anna Capogna1, Marco Bardelli1, Luca Cantarini1, Bruno Frediani1 | 1UOC Reumatologia, Dipartimento di Scienze mediche, chirurgiche e neuroscienze, Università degli Studi di Siena, Italy

    Società Italiana di Reumatologia
    25-11-2025
    https://doi.org/10.4081/reumatismo.2025.2200
    169
  • The Italian Society of Rheumatology clinical practice guidelines for the management of polymyalgia rheumatica

    N. Ughi, G.D. Sebastiani, R. Gerli, C. Salvarani, S. Parisi, A. Ariani, I. Prevete, M. Manara, F. Rumi, C.A. Sciré, A. Bortoluzzi
    1-15
    10-04-2020
    https://doi.org/10.4081/reumatismo.2020.1268
    6665
    PDF: 3719
  • Long term outcome of treatment of diffuse proliferative glomerulonephritis with pulse steroids and short course pulse cyclophosphamide

    C. Tani, M. Mosca, A. d'Ascanio, R. Neri, A. Tavoni, L. Carli, S. Bombardieri
    215-220
    https://doi.org/10.4081/reumatismo.2010.215
    1369
    PDF: 883
  • Reconstructing the pyramid as a therapeutic approach to rheumatoid arthritis

    G. Ferraccioli
    46-50
    https://doi.org/10.4081/reumatismo.2004.1s.46
    837
    PDF: 787
  • The Italian Society of Rheumatology clinical practice guidelines for the management of vaccines in adult patients with rheumatic diseases

    Nicola Ughi, Roberto Padoan, Giovanni Adami, Marta Mosca, Fabrizio Conti, Carlo Perricone, Matteo Piga, Serena Fasano, Roberto Caporali, Alessandra Bortoluzzi, Carlo Salvarani, Serena Bugatti, Serena Guiducci, Gian Domenico Sebastiani, Laura Sticchi, Giovanni Gabutti, Khadija El Aoufy, Silvia Tonolo, Greta Carrara, Gianpiero Landolfi, Davide Rozza, Andrea Doria
    09-04-2026
    https://doi.org/10.4081/reumatismo.2026.1895
    1027
    PDF: 157
  • Prevalence studies in rheumatology: the methodology of the Chiavari study

    M.A. Cimmino, A. Zampogna, S. Murroni, S. Baruffi, G. Alessio, T. Maio, G.S. Mela
    40-47
    https://doi.org/10.4081/reumatismo.2002.40
    1400
    PDF: 1174
  • PO:15:217 | Improved efficacy and safety outcomes in patients with systemic lupus erythematosus treated with belimumab vs. immunosuppressants, in addition to antimalarials and glucocorticoids: a post-hoc summary of five phase 3 trials Mariele Gatto1, Karen H. Costenbader2, Andreas Schwarting3, Julia Hn Harris4, Ciara O'Shea5, Roger A. Levy6, Andrea Doria7 | 1Centro Accademico Reumatologia, Dipartimento Scienze Cliniche Biologiche, Università degli Studi Torino, Osp. Mauriziano, Italy; 2Brigham and Women's Hospital, Divisione di Reumatologia, Infiammazione e Immunità, Harvard Medical School, Boston, MA, USA; 3Università Johannes Gutenberg di Mainz, Centro medico universitario, Germany; 4GSK, Immunologia Biostatistica London, UK; 5GSK, Global Medical Affairs Reumatologia, Dublin, Ireland; 6GSK, Global Medical Affairs Collegeville, PA, USA; 7Divisione di Reumatologia, Dipartimento di Medicina, Università di Padova, Italy

    Società Italiana di Reumatologia
    25-11-2025
    https://doi.org/10.4081/reumatismo.2025.2160
    188
  • PO:10:144 | Management of pure red cell aplasia as the onset of systemic lupus erythematosus: a case report Chrystel Carolin Navarrete Cadena1, Marika Tardella1 | 1Università Politecnica delle Marche Jesi, Ancona, Italy

    Società Italiana di Reumatologia
    18-03-2026
    https://doi.org/10.4081/reumatismo.2025.2310
    65
  • Children with Kawasaki disease or Kawasaki-like syndrome (MIS-C/PIMS) at the time of COVID-19: are they all the same? Case series and literature review

    A. Marino, T. Varisco, G. Quattrocchi, A. Amoroso, D. Beltrami, S. Venturiello, A. Ripamonti, A. Villa , M. Andreotti, M. Ciuffreda, R. Cimaz
    48-53
    19-04-2021
    https://doi.org/10.4081/reumatismo.2021.1331
    7951
    PDF: 1742
  • PO:06:083 | Clinical characteristics and outcomes of late- and young-onset rheumatoid arthritis in relation to autoantibody status Federica Sabatelli1|2, Ludovico De Stefano1|2, Clelia Zampaglione1|2, Lisa Bergianti1|2, Blerina Xoxi1|2, Antonio Manzo1|2, Carlomaurizio Montecucco1|2, Serena Bugatti1|2. | 1Department of Internal Medicine and Therapeutics, University of Pavia, Pavia; 2Division of Rheumatology, IRCCS Policlinico San Matteo Foundation, Pavia, Italy.

    Società Italiana di Reumatologia
    25-11-2025
    https://doi.org/10.4081/reumatismo.2025.2015
    148
  • Distress influence in fibromyalgia

    S. Stisi, C. Venditti, I. Saracco
    274-281
    https://doi.org/10.4081/reumatismo.2008.274
    1954
    PDF: 1419
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Reumatismo - The Italian Journal of Rheumatology

is the Official Journal of the Italian Society of Rheumatology (SIR). Founded in 1949. Published online by PAGEPress®, Pavia, Italy. All credits and honors to PKP for their OJS.

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