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PO:01:007 | Modulation of cellular senescence in psoriatic arthritis: exploring the potential impact of b/tsDMARDs treatment on telomere length, mtDNA copy number, and oxidative damage Eneida Cela1, Giada De Benedittis2, Arianna D'Antonio1, Andrea Latini3, Chiara Morgante2, Cinzia Cicacci3, Paola Conigliaro1, Mauro Fatica1, Giulia Mori1, Giuseppe Novelli2, Paola Borgiani2, Maria Sole Chimenti1. | 1Rheumatology, Allergology and Clinical Immunology, Department of System Medicine, University of Rome Tor Vergata, Rome, Italy; 2Department of Biomedicine and Prevention, Section of Genetics, University of Rome Tor Vergata, Rome, Italy; 3UniCamillus Saint Camillus International University of Health Sciences, Rome, Italy.
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CO:07:3 | Does articular and entheseal structural damage drive pain and patient-driven reported outcomes in difficult-to-treat psoriatic arthrtis patients? Results from a cross-sectional study Fabio Massimo Perrotta1, Alen Zabotti2, Mauro Fatica1, Nicola Cabas2, Andrea Guiotto2, Nicoletta Franzolini3, Giovanni Striani2, Maria De Martino4, Cristina De Nicola5, Miriam Isola4, Andrea Di Matteo6, Gabriele De Marco6, Denis McGonagle6, Ennio Lubrano1, Luca Quartuccio4. | 1Università degli studi del Molise, Campobasso; 2University Hospital Santa Maria della Misericordia, Udine; 3Presidio Ospedaliero S. Antonio, San Daniele del Friuli (UD); 4University of Udine; 5Epidemiology Unit, Italian Society for Rheumatology, Milano, Italy; 6University of Leeds, Leeds, UK
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PO:06:079 | Weighing the burden: how body mass index shapes clinical outcomes in rheumatoid arthritis. Insights from a large Italian cohort Marco Capodiferro1, Marco Fornaro1, Gian Luca Erre2, Matteo Piga3, Elena Bartoloni Bocci4, Andreina Manfredi5, Ennio Giulio Favalli6, Maria Sole Chimenti7, Serena Guiducci8, Eleonora Celletti9, Addolorata Corrado10, Alessandro Giollo11, Simone Parisi12, Ivan Giovannini13, Elisa Gremese14, Garifallia Sakellariou15, Ombretta Viapiana16, Fabiola Atzeni17, Francesca Romana Spinelli18, Fabio Cacciapaglia1|19. | 1Rheumatology Unit, Department of Precision and Regenerative Medicine and Ionian Area DiMePRe-J University of Bari, Bari, Italy; 2Dipartimento di Scienze Mediche, Chirurgiche e Sperimentali, Università degli Studi di Sassari, Sassari, Italy; 3Rheumatology Unit, AOU Cagliari, Department of Medical Sciences and Public Health, University of Cagliari, Cagliari, Italy; 4Rheumatology Unit, Department of Medicine and Surgery, University of Perugia, Perugia, Italy; 5Rheumatology Unit, Azienda Ospedaliera Universitaria Policlinico of Modena, Modena, Italy; 6Dpt of Rheumatology, G. Pini Institute, Milano, Italy; 7Rheumatology, Allergology and Clinical Immunology, Department of Systems Medicine, University of Rome Tor Vergata, Rome, Italy; 8Department of Experimental and Clinical Medicine, Division of Rheumatology, University of Florence, Firenze, Italy; 9Rheumatology Unit, SS Annunziata Hospital, Chieti, Italy; 10Rheumatology Unit, Department of Medical and Surgical Sciences, University of Foggia, Foggia, Italy; 11Rheumatology Unit, Department of Medicine, University of Padova Hospital Trust, Padova, Italy; 12Rheumatology Department, A.O.U. Città della Salute e della Scienza, Torino, Italy; 13Rheumatology Department, Santa Maria della Misericordia Hospital, Udine, Italy; 14Rheumatology and Clinical Immunology, IRCCS Humanitas Research Hospital, Rozzano (MI), Italy; 15Department of Internal Medicine and Therapeutics, University of Pavia, Istituti Clinici Scientifici Maugeri, Pavia, Italy; 16Rheumatology Unit, Department of Medicine, University and Azienda Ospedaliera Universitaria Integrata of Verona, Verona, Italy; 17Rheumatology Unit, Department of Experimental and Internal Medicine, University of Messina, Messina, Italy; 18Reumatology Unit, Department of Internal, Anesthesiological, and Cardiovascular Clinical Sciences, Sapienza University, Roma, Italy; 19Miulli General Hospital Acquaviva - Department of Medicine and Surgery, LUM F. De Gennaro University, Casamassima (BA), Acquaviva delle Fonti (BA), Italy.
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PO:08:113 | Shaping rheumatoid arthritis treatment: clinical and demographic drivers of tsDMARDs versus bDMARDs prescription post-EMA pronouncement on JAK inhibitors - insights from the AMBI-RA study Riccardo Bertola1, Beatrice Maranini1, Carlo Garaffoni1, Maria Pozzuto1, Anna Laura Riva Cambrino1, Alessandro Spinelli1, Letizia Mamprin1, Federico Agostini1, Martina Di Nunzio1, Marcello Govoni1, Alessandra Bortoluzzi1, Ettore Silvagni1 | 1Rheumatology Unit, Department of Medical Sciences, University of Ferrara and Azienda Ospedaliero-Universitaria S. Anna, Italy
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CO:02:4 | Whole blood hypercoagulable profiles in patients with rheumatoid arthritis Lorenzo Di Luozzo1, Alessandro Giollo1, Mariangela Salvato1, Francesca Frizzera1, Kiren Khalid1, Luca Spiezia2, Andrea Benetti2, Chiara Samà2, Paolo Simioni2, Andrea Doria1. | 1Unità di Reumatologia, Azienda Ospedaliera di Padova; 2Dipartimento di Medicina, Università di Padova, Italy
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CO:10:3 | Clinical response to JAK inhibitors or non-TNFi-targeted biologicals according to synovial tissue characteristics in patients with difficult-to-treat rheumatoid arthritis Mariangela Salvato1, Alessandro Giollo1, Francesca Frizzera1, Kiren Khalid1, Lorenzo Di Luozzo1, Maria Capita1, Marianna Tamussin1, Carlo Garaffoni2, Marny Fedrigo3, Annalisa Angelini3, Ettore Silvagni2, Andrea Doria1. | 1Rheumatology Unit, Department of Medicine - DIMED, University of Padova; 2Rheumatology Unit, Department of Medical Sciences, University of Ferrara and Azienda Ospedaliero-Universitaria S. Anna; 3Cardiovascular Pathology, Department of Cardiac, Thoracic, Vascular Sciences and Public Health, University of Padova, Italy
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PO:02:017 | Difficult-to-treat psoriatic arthritis: clinical and ultrasonographic predictors in a real-life cohort Federico Favaro1, Elisa Bellis1, Claudio Cruciani1, Gloria Crepaldi1, Valeria Data1, Claudia Garulli1, Claudia Lomater1, Elena Marucco1, Marta Saracco1, Mariele Gatto1, Annamaria Iagnocco1. | 1Academic Rheumatology Centre, Departement of Clinical and Biological Sciences, University of Turin, AO Mauriziano, Torino, Italy.
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PO:07:095 | Clinical impact of therapeutic modification following changes in AIFA reimbursement criteria for JAK inhibitors in patients with RA in remission/low disease activity: analysis of the multicenter JAK-SWAP RER study in Emilia-Romagna Marta Raschella1, Giulia Furia1, Martina Di Nunzio1, Francesco Luca Renzullo2, Francesco Girelli2, Federica Pignatti3, Francesco Ursini3, Licia Vultaggio4, Pierluigi Cataleta4, Elena Bravi5, Eugenio Arrigoni5, Francesca Bergossi6, Enrica Vandelli7, Massimo Reta6|7, Viola Magnani8, Andreina Manfredi8|9, Giuseppe Germanò8, Alessandra Bortoluzzi1, Marcello Govoni1, Ettore Silvagni1 | 1Unità Operativa Complessa di Reumatologia, Dipartimento di Scienze Mediche, Università degli Studi di Ferrara e Azienda Ferrara; 2UOS Reumatologia, Ospedale GB Morgagni, Forlì; 3UOC Reumatologia, Istituto ortopedico Rizzoli, Bologna; 4UO Reumatologia, AUSL Romagna Ospedale di Ravenna; 5UO Reumatologia, Azienda USL di Piacenza; 6Reumatologia Osp. Maggiore, Bologna; 7UO Medicina Interna ad Indirizzo Reumatologico Interaziendale SC AUSL Bologna, IRCCS Policlinico di SantOrsola, Bologna; 8U.O Reumatologia, Santa Maria Nuova di Reggio Emilia; 9Università degli studi di Modena e Reggio Emilia, Italy
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PO:06:093 | Clinical and ultrasound phenotyping comparison between Difficult-To-Treat Rheumatoid Arthritis (D2TRA) and non-D2TRA patients: experience from a monocentric cohort Silvia Perrone1, Claudio Cruciani1, Silvia Mascolo1, Elisa Bellis1, Gloria Crepaldi1, Valeria Data1, Claudia Garulli1, Claudia Lomater1, Elena Marucco1, Marta Saracco1, Mariele Gatto1, Annamaria Iagnocco1. | 1Academic Rheumatology Centre, Department of Clinical and Biological Sciences, University of Turin, AO Mauriziano, Turin, Italy.
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PO:04:061 | Higher prevalence of baseline comorbidities in patients developing difficult to treat psoriatic arthritis Mario Ferraioli1, Michelina Turri1, Eneida Çela1, Mauro Fatica1, Paola Conigliaro1, Elisabetta Greco1, Alberto Bergamini1, Maria Sole Chimenti1. | 1Rheumatology, Allergology and Clinical Immunology, Department of Systems Medicine, University of Rome, Tor Vergata, Rome, Italy.
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