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• PO:22:029 | Impact of mepolizumab on idiopathic hypereosinophilic syndromes: analysis of a monocentric retrospective cohort Jacopo Mora¹, Francesca Regola¹, Paola Toniati², Ilaria Cavazzana¹, Franco Franceschini¹. | ¹ASST Spedali Civili e Università degli Studi di Brescia, Brescia, Italy; ²ASST Spedali Civili di Brescia, Brescia, Italy.

  Società Italiana di Reumatologia

  25-11-2025

  https://doi.org/10.4081/reumatismo.2025.2053

  133

• PO:37:260 | Mepolizumab in the treatment of patients with eosinophilic granulomatosis with polyangiitis: real-life experience from a single-center cohort Eleonora Bruschi¹, Fabrizio Angeli¹, Alessandro Belotti Masserini¹, Stefania Bertocchi¹, Silvia Breda¹, Elide Lupi¹, Valeria Rossi¹, Tania Ubiali¹, Massimiliano Limonta¹ | ¹ASST Papa Giovanni XXIII Bergamo Italy

  Società Italiana di Reumatologia

  25-11-2025

  https://doi.org/10.4081/reumatismo.2025.2220

  150

• PO:35:218 | Switching the dose of mepolizumab in patients with Eosinophilic Granulomatosis with Polyangiitis (EGPA): a European retrospective multicentre real-world study Edoardo Biancalana¹, Irene Mattioli¹, Emanuele Chiara², Danilo Malandrino¹, Maria Canfora¹, Palmerini Miki¹, Maria Paola Lisi¹, Michela Gasparotto³, Paola Tomietto³, Maria Letizia Urban¹, Giacomo Bagni¹, Elena Silvestri¹, Alessandra Bettiol³, Augusto Vaglio³, Giacomo Emmi² | ¹Department of Experimental and Clinical Medicine, University of Florence Firenze, Italy; ²Department of Medical, Surgery and Health Sciences, University of Trieste Trieste, Italy; ³Clinical Medicine and Rheumatology Unit, Cattinara University Hospital, Trieste, Trieste, Italy; ⁴Department of Biomedical, Experimental and Clinical Sciences Mario Serio, University of Florence Firenze, Italy

  Società Italiana di Reumatologia

  18-03-2026

  https://doi.org/10.4081/reumatismo.2025.2381

  30

• PO:35:234 | Sustained Vasculitis Quiescence and CS Reduction with Mepolizumab 100 mg Francesca Mascia¹, Angelo Fassio², Marco Zurlo¹, Davide Chesini³, Francesco Pollastri², Giovanni Adami², Davide Gatti⁴, Maurizio Rossini⁴, Matteo Maule⁵, Gianentrico Senna¹, Marco Caminati¹ | ¹University of Verona - Allergology and Clinical Immunology Verona, Italy; ²Policlinico G. B. Rossi - Rheumatology Verona, Italy; ³University of Verona - Faculty of Medicine and Surgery Verona, Italy; ⁴University of Verona - Rheumatology Verona, Italy; ⁵Policlinico G. B. Rossi - Allergology and Clinical Immunology Verona, Italy

  Società Italiana di Reumatologia

  18-03-2026

  https://doi.org/10.4081/reumatismo.2025.2387

  20

• PO:11:162 | DRESS syndrome: a case treated with mepolizumab Alessandro Belotti Masserini¹, Stefania Bertocchi¹, Eleonora Bruschi¹, Silvia Breda¹, Valeria Rossi¹, Elide Lupi¹, Tania Ubiali¹, Fabrizio Angeli¹, Massimiliano Limonta¹ | ¹ASST Papa Giovanni XXIII, Bergamo, Italy

  Società Italiana di Reumatologia

  25-11-2025

  https://doi.org/10.4081/reumatismo.2025.2152

  180

• PO:35:219 | Real-world effectiveness of mepolizumab on gastrointestinal involvement in eosinophilic granulomatosis with polyangiitis and hypereosinophilic syndrome: a multicentre retrospective study Alessia Gatti¹, Francesca Regola¹, Giulia Fontana¹, Mario Addrea Piga², Gianluca Moroncini², Palma Carlucci³, Angelo Vacca³, Paolo Delvino⁴, Enrico Heffler⁵, Emanuele Nappi⁵, Jakub Moll⁶, Laura Losappio⁶, Jan Schroeder⁶, Federica Davanzo⁷, Roberto Padoan⁷, Edoardo Conticini⁸, Paolo Cameli⁸, Greta Pacini⁹, Alvise Berti⁹, Lorenzo Vrola¹⁰, Paola Tomietto¹⁰, Luca Quartuccio¹¹, Jan Willem Cohen Tervaert¹², Sabrina Arnold¹³, Peter Lamprecht¹³, Florence Roufosse¹⁴, Ilaria Cavazzana¹, Franco Franceschini¹, Giacomo Emmi¹⁵, Paola Toniati¹. | ¹Rheumatology and Clinical Immunology Unit, ERN ReCONNET, ASST Spedali Civili of Brescia and University of Brescia, Italy, Brescia, Italy; ²Università Politecnica delle Marche and Azienda Ospedaliero Universitaria delle Marche, Ancona, Italy, Ancona, Italy; ³Section of Internal Medicine 'Guido Baccelli', DiMePRe-J, University of Bari 'Aldo Moro', Bari, Italy, Bari, Italy; ⁴Rheumatology Unit, IRCCS San Gerardo dei Tintori, Monza, Italy Monza Italy; ⁵Department of Biomedical Sciences, Humanitas University and Personalized Medicine, Asthma and Allergy IRCCS Humanitas, Milano, Italy; ⁶Division of Allergy and Clinical Immunology, ASST GOM Niguarda, Milan, Italy, Milano, Italy; ⁷Rheumatology Unit, Department of Medicine DIMED, University of Padua, Padova, Italy, Padova, Italy; ⁸University of Siena, Siena, Italy, Siena, Italy; ⁹Santa Chiara Hospital and University of Trento, Unit of Rheumatology, Trento, Italy Trento Italy; ¹⁰UCO Medicina Clinica, ASUGI, Cattinara Teaching Hospital, Trieste, Italy, Trieste, Italy; ¹¹Division of Rheumatology, Department of Medicine ^DMED, University of Udine, Udine, Italy, Udine, Italy; ¹²University of Alberta, Edmonton, Alberta, Canada and Maastricht University, Maastricht, The Netherlands Maastricht The Netherlands; ¹³Department of Rheumatology and Clinical Immunology, University of Lübeck, Lübeck, Germany Lubeck Germany; ¹⁴Department of Internal Medicine, Hôpital Universitaire de Bruxelles - Erasme, Université Libre de Bruxelles, Belgium Brussels Belgium; ¹⁵Clinical Medicine and Clinical Immunology and Rheumatology Unit Cattinara University Hospital and University of Trieste, Trieste, Italy.

  Società Italiana di Reumatologia

  25-11-2025

  https://doi.org/10.4081/reumatismo.2025.2086

  186
• 

  Eosinophilic granulomatosis with polyangiitis: sequential use of mepolizumab following rituximab for inadequate asthma control despite vasculitis remission

  B. Cremonezi Lammoglia, L. de Aguiar Trevise, T. Paslar Leal, M. Pereira Lopes Vieira Pinto, G. Hasselmann, N. Salles Rosa Neto

  19-12-2023

  https://doi.org/10.4081/reumatismo.2023.1588

  1540

  PDF: 558

• PO:37:258 | Neutrophil and eosinophil extracellular traps in eosinophilic granulomatosis with polyangiitis: phenotype-based characterization and response to mepolizumab Michele Moretti¹, Francesco Ferro², Francesco Pisani¹, Elisa Ferrigno¹, Gaetano La Rocca¹, Federica Di Cianni³, Rosaria Talarico², Marta Mosca¹, Chiara Baldini¹, Ilaria Puxeddu¹. | ¹University of Pisa - Department of Clinical and Experimental Medicine, Pisa, Italy; ²Azienda Ospedaliero Universitaria Pisana - Rheumatology Unit, Pisa, Italy; ³University of Siena, Siena, Italy.

  Società Italiana di Reumatologia

  25-11-2025

  https://doi.org/10.4081/reumatismo.2025.2096

  144

• PO:35:223 | Biologic therapy for sustained remission in eosinophilic myocarditis: real-world evidence from a tertiary center experience Federica Davanzo¹, Caterina Menghi², Andrea Silvio Giordani², Anna Baritussio², Federico Scognamiglio², Cristina Vicenzetto², Luca Iorio¹, Renzo Marcolongo², Cristina Basso³, Andrea Doria¹, Roberto Padoan¹, Alida Linda Patr Caforio² | ¹Rheumatology Unit, Department of Medicine, University of Padua Padova, Italy; ²Cardiology Unit, Department of Cardiac, Vascular, Thoracic Sciences and Public Health, University of Padua Padova, Italy; ³Cardiovascular Pathology, Department of Cardiac, Thoracic and Vascular Sciences and Public Health, University of Padua Padova, Italy

  Società Italiana di Reumatologia

  18-03-2026

  https://doi.org/10.4081/reumatismo.2025.2383

  25

• PO:36:250 | Eosinophilic granulomatosis with polyangiitis associated to Alpha-1 Antitrypsin Deficiency: a land still unexplored Maria Grazia Malandra¹, Vacchi Caterina¹, Santoro Filippo¹, Cassone Giulia¹, Martina Orlandi¹, Stefania Cerri¹, Dilia Giuggioli¹ | ¹Università di Modena - Reggio Emilia, S.C. Reumatologia Azienda Ospedaliera Universitaria Policlinico di Modena Modena, Italy; ²S.C. Reumatologia Azienda Ospedaliera Universitaria Policlinico di Modena Modena, Italy; ³Università di Modena e Reggio Emilia, S.C. Reumatologia Azienda Ospedaliera Universitaria Policlinico di Modena Modena, Italy; ⁴S.C. Reumatologia Azienda Ospedaliera Universitaria Policlinico di Modena Modena, Italy; ⁵Università di Modena e Reggio Emilia, S.C. Reumatologia Azienda Ospedaliera Universitaria Policlinico di Modena Modena, Italy; ⁶Università di Modena e Reggio Emilia, S.C. Reumatologia Azienda Ospedaliera Universitaria Policlinico di Modena Modena, Italy; ⁷Università di Modena e Reggio Emilia, S.C. Reumatologia Azienda Ospedaliera Universitaria Policlinico di Modena Modena, Italy

  Società Italiana di Reumatologia

  18-03-2026

  https://doi.org/10.4081/reumatismo.2025.2388

  17

• S02:5 | Combined anti-IL-5/IL-5r and dupilumab therapy in eosinophilic granulomatosis with polyangiitis: a European retrospective study Miriam Guerini¹, Pavel Novikov², Roberto Padoan³, Georgina Espigol Frigolé⁴, Jan Willem Cohen Tervaert⁵, Vincent Grobost⁶, Laurent Guilleminault⁷, Jan Walter Schroeder⁸, Bernhard Hellmich⁹, Joana Martins Martinho¹⁰, Camillo Ribi¹¹, Matthieu Groh¹², Benjamin Terrier¹³. | ¹IRCCS Policlinico S. Matteo, University of Pavia, Pavia, Italy; ²Sechenov University, Moscow, Russia; ³University of Padova, Padova, Italy; ⁴Hospital Clinic, University of Barcelona, Barcelona, Spain; ⁵University of Alberta, Edmonton, Canada; ⁶CHU Estaing Clermont-Ferrand France; ⁷Toulouse University Toulouse France; ⁸ASST Grande Ospedale Metropolitano Niguarda, Milano, Italy; ⁹Medius Kliniken Kirchheim-Teck Germany; ¹⁰ULS Santa Maria, Lisbon, Portugal; ¹¹Centre Hospitalier Universitaire Vaudois, Lausanne, Switzerland; ¹²Hopital Foch, Suresnes, France; ¹³Service de Medecine interne, Hopital Cochin, AP-HP, Paris, France.

  Società Italiana di Reumatologia

  25-11-2025

  https://doi.org/10.4081/reumatismo.2025.2101

  191

• PO:35:224 | Capturing What BVAS Misses: Patient-Reported Outcomes Reflect Disease Activity and Burden in EGPA Marta Codirenzi¹, Federica Davanzo¹, Luca Iorio¹, Eleonora Fiorin¹, Roberta Prevedello¹, Roberto Padoan¹, Andrea Doria¹ | ¹Unità di reumatologia, dipartimento di medicina DIMED,Università degli studi di Padova, Italy

  Società Italiana di Reumatologia

  18-03-2026

  https://doi.org/10.4081/reumatismo.2025.2384

  16