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• PO:15:209 | Attainment of remission or lupus low disease activity state in single center Lupus Clinic Paola Tedoldi^1|2, Silvia Ebe Lucia Della Pina^1|2, Claudia Barison^1|2, Chiara Orlandi^1|2, Cecilia Nalli¹, Micaela Fredi², Ilaria Cavazzana^1|2, Franco Franceschini^1|2 | ¹Rheumatology and Clinical Immunology Unit- ERN ReCONNET, ASST Spedali Civili of Brescia Brescia, Italy; ²Department of Clinical and Experimental Sciences, University of Brescia Brescia, Italy

  Società Italiana di Reumatologia

  18-03-2026

  https://doi.org/10.4081/reumatismo.2025.2325

  27

• PO:14:198 | Temporal Trends in LLDAS and DORIS Achievement in SLE: Impact of Evolving International Recommendations Laura Coladonato¹, Marco Fornaro¹, Angelica Napoletano¹, Daniele Catamerò¹, Giuseppe Lopalco¹, Florenzo Iannone¹ | ¹UOC Reumatologia, Policlinico di Bari, DiMePre-J Bari, Italy

  Società Italiana di Reumatologia

  18-03-2026

  https://doi.org/10.4081/reumatismo.2025.2321

  21

• PO:16:236 | Achieving a low disease activity state with a corticosteroid dose of 5 mg or less: observational study with anifrolumab in patients with systemic lupus erythematosus in Italy Alessandra Bortoluzzi¹, Fulvia Ceccarelli², Fabio Leo³, Paola Roccatagliata³, Chiara Tani⁴, Margherita Zen⁵ | ¹Azienda Ospedaliera Universitaria Sant' Anna di Cona, Università di Ferrara Italy; ²Unità di Reumatologia, Università Sapienza Roma Italy; ³AstraZeneca S.p.a. Milano Italy; ⁴Università di Pisa e Azienda Ospedaliero Universitaria Pisana, Pisa Italy; ⁵Dipartimento di Medicina DIMED , Divisione di Reumatologia, Università di Padova, Italy

  Società Italiana di Reumatologia

  25-11-2025

  https://doi.org/10.4081/reumatismo.2025.2163

  110

• PO:15:218 | Evaluation of leukocyte expression of ecto-nucleotidase in patients with systemic lupus erythematosus Luca Rapino¹, Simona Truglia¹, Fulvia Ceccarelli¹, Francesca Romana Spinelli¹, Silvia Mancuso¹, Giada La Spina¹, Hector Rincon Arvalo², Thomas Doerner², Ana Luisa Stefanski², Fabrizio Conti¹. | ¹La Sapienza Università di, Roma, - Dipartimento di Scienze Cliniche Internistiche Anestesiologiche e Cardiovascolare, Roma, Italy; ²Charité Universitätsmedizin - Department of Rheumatology and Clinical Immunology, Berlino, Germany.

  Società Italiana di Reumatologia

  25-11-2025

  https://doi.org/10.4081/reumatismo.2025.2038

  117

• PO:17:255 | Efficacy and safety of voclosporin in the management of lupus nephritis: a case series Alessandra Oliva¹, Elisabetta Chessa², Marta Paola Pireddu¹, Marianna Salis¹, Giulia Rizzo¹, Fabio Congiu¹, Elena Ragusa¹, Antonello Pani^3|4, Alberto Cauli^1|2, Nicola Lepori^3|4, Matteo Piga^1|2 | ¹UOC Reumatologia, Dipartimento di Scienze Mediche e Salute Pubblica, Università degli Studi di Cagliari; ²UOC Reumatologia, AOU Cagliari; ³SC Nefrologia e Dialisi, Università degli Studi di Cagliari; ⁴SC Nefrologia e Dialisi, Azienda Ospedaliera Brotzu, Cagliari, Italy

  Società Italiana di Reumatologia

  25-11-2025

  https://doi.org/10.4081/reumatismo.2025.2169

  141

• PO:17:253 | Unveiling the gap: a multicenter study on factors driving patient-physician discrepancies in assessing disease activity in systemic lupus erythematosus Giorgia Ingrid Gozzoli¹, Micaela Fredi¹, Federica Bonaso¹, Silvia Ebe Lucia Della Pina¹, Claudia Barison¹, Irene Lorenzini⁴, Raffaele Pericotti⁴, Anna Mattiuzzo⁴, Marcelo Neto², Sofia Azevedo³, Cláudia Oliveira³, Cesare Tomasi⁴, Luís Sousa Inês², Franco Franceschini¹. | ¹Rheumatology and Clinical Immunology Unit, ASST Spedali Civili of Brescia, Brescia, Italy; ²Rheumatology Department, Centro Hospitalar Universitário de Coimbra - ULS Coimbra, Coimbra, Portugal; ³Rheumatology  Department, ULS Aveiro, Aveiro, Portugal; ⁴Department of Clinical and Experimental Sciences, University of Brescia, Brescia, Italy.

  Società Italiana di Reumatologia

  25-11-2025

  https://doi.org/10.4081/reumatismo.2025.2046

  139

• PO:14:203 | Impact of anifrolumab on depressive symptoms in systemic lupus erythematosus: results from a single-centre prospective observational study Luca Moroni¹, Biancamaria Venerandi¹, Maria Cilona¹, Anna Vivona¹, Gabriele Gallina¹, Giovanni Benanti¹, Enrica Bozzolo¹, Giuseppe Ramirez¹, Marco Matucci-Cerinic¹, Lorenzo Dagna¹. | ¹U.O. di Immunologia, Reumatologia, Allergologia e Malattie Rare - IRCCS Ospedale San Raffaele, Milano, Italy.

  Società Italiana di Reumatologia

  25-11-2025

  https://doi.org/10.4081/reumatismo.2025.2032

  127

• CO:11:2 | Systemic lupus erythematosus with major neuropsychiatric involvement treated with anifrolumab: literature review and a case report Giulia Rizzo¹, Fabio Congiu¹, Elisabetta Chessa², Marta Paola Pireddu¹, Elena Ragusa¹, Alessandra Oliva¹, Marianna Salis¹, Alberto Cauli^1|2, Matteo Piga^1|2 | ¹SC Reumatologia, Dipartimento di Scienze Mediche e Salute Pubblica, Università di Cagliari Italy; ²SC Reumatologia, AOU Cagliari Italy

  Società Italiana di Reumatologia

  25-11-2025

  https://doi.org/10.4081/reumatismo.2025.2120

  206

• PO:15:208 | Impact of disease control on organ damage accrual in patients with systemic lupus erythematosus with and extra-renal flares: a 12-month single-center longitudinal study Giorgia Capozzo¹, Marco Oliva¹, Giancarlo Cascarano¹, Chiara Cardelli¹, Dina Zucchi¹, Chiara Stagnaro², Viola Signorini², Elena Elefante², Chiara Tani¹, Marta Mosca¹. | ¹Università di Pisa, Dipartimento di Medicina Clinica e Sperimentale, Pisa, Italy; ²Azienda Ospedaliero Universitaria Pisana, U.O. Reumatologia, Pisa, Italy.

  Società Italiana di Reumatologia

  25-11-2025

  https://doi.org/10.4081/reumatismo.2025.2037

  140

• PO:15:220 | Outcomes of extra renal flares in systemic lupus erythematosus: longitudinal analysis of a monocentric cohort Marco Oliva¹, Giorgia Capozzo¹, Giancarlo Cascarano¹, Chiara Cardelli¹, Dina Zucchi¹, Angela Elia¹, Elena Elefante², Viola Signorini², Chiara Stagnaro², Chiara Tani¹, Marta Mosca¹. | ¹Rheumatology Unit, Department of Clinical and Experimental Medicine, University of Pisa, Pisa, Italy; ²Rheumatology Unit, AOUP, Pisa, Italy.

  Società Italiana di Reumatologia

  25-11-2025

  https://doi.org/10.4081/reumatismo.2025.2040

  129

• PO:15:214 | Identification of SLE patients with high-levels Type 2 SLE through the polysymptomatic distress scale (PSD): correlations with other PROs and differences in clinical phenotypes in a multicentric cohort Micaela Fredi^1|2, Giorgia Gozzoli^1|2, Federica Bonaso^1|2, Silvia Ebe Della Pina^1|2, Claudia Barison^1|2, Irene Lorenzini², Anna Mattiuzzo², Raffaele Pericotti², Marcelo Neto³, Sofia Avedo⁴, Clàudia Oliveira⁴, Luis Sousa Ines³, Franco Franceschini^1|2 | ¹Rheumatology and Clinical Immunology, ASST Spedali Civili of Brescia, ERN-ReCONNET Center, Brescia, Italy; ²Department of Clinical and Experimental Sciences, University of Brescia, Brescia, Italy; ³Rheumatology Department, Centro Hospitalar Universitário de Coimbra - ULS Coimbra, Coimbra, Portugal; ⁴Rheumatology Department, ULS Aveiro, Aveiro, Portugal

  Società Italiana di Reumatologia

  18-03-2026

  https://doi.org/10.4081/reumatismo.2025.2327

  9

• CO:10:6 | Impact of pregnancy on organ damage in systemic lupus erythematosus: a prospective multicenter study Giancarlo Cascarano¹, Greta Hulej², Dina Zucchi¹, Antonia Calligaro², Elena Elefante¹, Luca Iaccarino², Sabrina Gori¹, Margherita Zen², Chiara Tani¹, Andrea Doria², Marta Mosca¹. | ¹Università degli Studi di Pisa; ²Università degli Studi di Padova, Italy

  Società Italiana di Reumatologia

  25-11-2025

  https://doi.org/10.4081/reumatismo.2025.1995

  131

• PO:14:195 | Real-world effectiveness of anifrolumab in achieving treatment targets and reducing systemic lupus erythematosus disease burden: 6-month interim analysis of the REVEAL study Chiara Cardelli^1|2, Chiara Tani¹, Luca Moroni³, Filippo Vesentini⁴, Francesca Bottazzi⁵, Micaela Fredi⁶, Ettore Silvagni⁷, Matteo Piga⁸, Flavia Riccio⁹, Fulvia Ceccarelli¹⁰, Ginevra De Marchi¹¹, Edoardo Biancalana¹², Gianluca Moroncini¹³, Rita Mulè¹⁴, Mariele Gatto¹⁵, Laura Coladonato¹⁶, Paola Conigliaro¹⁷, Maria Gerosa¹⁸, Andrea Picchianti Diamanti¹⁹, Benedetta Bianchi²⁰, Federica Maiolini²⁰, Michela Gasparotto²⁰, Serena Guiducci²⁰, Maria Ilenia De Andres²⁰, Alberto Lo Gullo²⁰, Silvia Noviello²⁰, On Behalf Of The Reveal Investigators²⁰, Marta Mosca¹. | ¹Rheumatology Unit, Department of Clinical and Experimental Medicine, University of Pisa, Pisa; ²Department of Medical Biotechnologies, University of Siena, Siena; ³Unit of Immunology, Rheumatology, Allergy and Rare Diseases, IRCCS San Raffaele Hospital, Milano; ⁴Rheumatology Unit, Department of Medicine, University of Padua, Padova; ⁵Department of Internal Medicine and Therapeutics, University of Pavia, Pavia; ⁶Rheumatology and Clinical Immunology, Department of Clinical and Experimental Sciences, University of Brescia, Brescia; ⁷Section of Rheumatology, Department of Medical Sciences, University of Ferrara; AOU Sant'Anna, Ferrara; ⁸Rheumatology Unit, Department of Medical Sciences and Public Health, University of Cagliari, Cagliari;  ⁹Department of Precision Medicine, University of Campania Luigi Vanvitelli, Napoli; ¹⁰Rheumatology Unit, Dept. of Clinical Internal, Anesthesiological and Cardiovascular Sciences, Sapienza University of Rome, Roma; ¹¹Division of Rheumatology, Department of Medicine, Azienda Sanitaria Universitaria del Friuli Centrale, Udine; ¹²Internal Interdisciplinary Medicine Unit, Department of Experimental and Clinical Medicine, University of Florence, Firenze; ¹³Department of Clinical and Molecular Sciences, Marche Polytechnic University, Ancona; ¹⁴Azienda Ospedaliero-Universitaria di Bologna, Internal Medicine and Rheumatology, IRCCS S. Orsola Malpighi, Bologna; ¹⁵Academic Rheumatology Centre, Department of Clinical and Biological Sciences, University of Turin; AO Mauriziano, Torino; ¹⁶Rheumatology Unit, Department of Precision and Regenerative Medicine and Ionian Area, University of Bari, Bari; ¹⁷Rheumatology, Allergology and Clinical Immunology, Department of Systems Medicine, Tor Vergata University of Rome, Roma; ¹⁸Clinical Rheumatology, ASST Gaetano Pini CTO; Department of Clinical Sciences and Community Health, University of Milano, Milano; ¹⁹Department of Clinical and Molecular Medicine, Sapienza University of Rome; AOU Sant'Andrea, Roma, Italy; ²⁰Italian REVEAL Study Group Italy, Italy

  Società Italiana di Reumatologia

  25-11-2025

  https://doi.org/10.4081/reumatismo.2025.2031

  146