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PO:33:199 | Prevalence and clinical associations of antiphospholipid antibodies in patients with systemic sclerosis in the SPRING-SIR registry Antonio Tonutti1|2, Ilaria Cavazzana3, Angela Ceribelli1|2, Maria De Santis1|2, Giacomo De Luca4|5, Maria Grazia Lazzaroni3, Franco Franceschini3, Carlo Selmi1|2, Valeria Riccieri6, Silvia Laura Bosello7, Fabio Cacciapaglia8, Veronica Codullo9, Francesca Ingegnoli10, Dilia Giuggioli11, Rossella De Angelis12, Clodoveo Ferri11, Marco Matucci-Cerinic4|5 | 1Department of Biomedical Sciences, Humanitas Universityce Pieve Emanuele, Milan, Italy; 2Rheumatology and Clinical Immunology, IRCCS Humanitas Research Hospital Rozzano, Milan, Italy; 3Rheumatology and Clinical Immunology - ASST Spedali Civili Brescia - Department of Clinical and Experimental Sciences - Brescia, Italy; 4Vita-Salute San Raffaele University Milan, Italy; 5Unit of Immunology, Rheumatology, Allergy and Rare Diseases UnIRAR and INFLAGE Initiative, IRCCS San Raffaele Hospital Milan, Italy; 6University of Rome La Sapienza Rome, Italy; 7Catholic University of Sacred Heart Rome, Italy; 8LUM University Bari, Italy; 9Rheumatology Unit, Fondazione IRCCS Policlinico San Matteo Pavia, Italy; 10University of Milan Milan, Italy; 11University of Modena and Reggio Emilia Modena, Italy; 12Politechnic University of Marche Ancona, Italy
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PO:15:221 | Proteins upregulated in thrombotic antiphospholipid syndrome link to platelet function in contrast with non-antiphospholipid-related thrombosis: insights from two systematic reviews Silvia Mancuso1, Claudia Ciancarella1, Luca Rapino1, Simona Truglia1, Cristiano Alessandri1, Fabrizio Conti1. | 1Dipartimento di Scienze Cliniche Internistiche, Anestesiologiche e Cardiovascolari - Rheumatology Unit, Sapienza Univers, Roma, Italy.
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PO:10:149 | Efficacy of anifrolumab in a case of systemic lupus erythematosus with pulmonary involvement Fabio Brandolino1, Giulia Pazzola1, Luca Ronzoni3, Andreina Teresa Manfredi1|2, Carlo Salvarani1|2 | 1SC Reumatologia, IRCCS Arcispedale Santa Maria Nuova, AUSL Reggio Emilia; 2Università di Modena e Reggio Emilia, Scuola di specializzazione in Reumatologia, Modena; 3SC Malattie dell'Apparato Respiratorio, IRCCS Arcispedale Santa Maria Nuova, AUSL Reggio Emilia, Italy
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PO:14:205 | Primary antiphospholipid antibody syndrome: association between new classification criteria manifestations and a higher-risk disease phenotype Sara Ferrigno1, Vittorio Forte2, Marco Panetta1, Sergio Lisena1, Giorgia Ranucci2, Luigi De Marco1, Elisabetta Greco1, Alberto Bergamini1, Maria Sole Chimenti1, Paola Conigliaro1. | 1Rheumatology, allergology and clinical immunology, Department of Systems Medicine, University of Rome Tor Vergata, Rome, Italy; 2Hematology, Department of Biomedicine and Prevention, University of Rome Tor Vergata, Rome, Italy.
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PO:10:155 | Etanercept-induced lupus in a patient with rheumatoid arthritis: diagnostic challenges and multidisciplinary therapeutic approach Camilla Riboldi1|2, Claudia Iannone1|2, Maria Gerosa1|2, Roberto Felice Caporali1|2 | 1ASST G. Pini-CTO, U.O.C. di Clinica Reumatologica, Milano; 2Dipartimento di Scienze Cliniche e di Comunità, Università degli Studi di Milano, Italy
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PO:14:199 | Preliminary data of a multicentric study on safety and efficacy of assisted reproductive techniques in pregnant women with systemic autoimmune diseases Valentina Canti1, Maria Bernadette Cilona1, Giuditta Gorgone1, Federica Pasi1, Antonia Calligaro2, Francesca Ruffilli3, Francesca Crisafulli6, Maria Tonello2, Eleonora Giacobbe4, Alba Chiara Pozzi6, Maria Chiara Gerardi4, Melissa Padovan3, Emanuele Bizzi5, Enrico Papaleo1, Beatrice Maranini3, Marcello Govoni3, Massimiliano Epis4, Angela Tincani6, Andrea Doria2, Patrizia Rovere Querini1 | 1IRCCS Ospedale San Raffaele and VitaSalute San Raffaele Milano, Italy; 2Rheumatology Unit, Departement of Medicine, University Hospital of Padua Padova, Italy; 3Rheumatology Unit, Azienda Ospedaliero Universitaria S. Anna Ferrara, Department of Medical Sciences, University of Fe Ferrara, Italy; 4ASST Grande Ospedale Metropolitano Niguarda Milano, Italy; 5Internal Medicine, Fatebenefratelli Hospital Milano, Italy; 6Rheumatology and Immunology Unit, ASST Spedali Civili Brescia e Università degli Studi di Brescia, Italy
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CO:11:5 | Laboratory preliminary results from an open label, prospective, phase ii descriptive pilot trial of belimumab therapy for refractory and/or non criteria manifestations of antiphospholipid syndrome Alice Barinotti1, Massimo Radin1, Irene Cecchi1, Beatrice Ala1, Chiara Raymondi1, Elena Rubini1, Silvia G. Foddai1, Lois Ira Maniulit Capulong1, Alessio Conti1, Alessandro Morotti1, Dario Roccatello1, Roberta Fenoglio1, Savino Sciascia1. | 1Università di Torino, Italy.
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PO:16:233 | Efficacy of voclosporin on nephritis in patients with variable gain of function of TLR7 affected by lupus: clinical case Veronica Spedicato1, Laura Coladonato1, Marco Fornaro1, Marlea Lavista1, Daniele Sabella1, Marco Capodiferro1, Maria Morrone1, Crescenzio Scioscia1, Giuseppe Lopalco1, Florenzo Iannone1 | 1Unit of Rheumathology, Department of Precision and Regenerative Medicina, Area JonicaJ, University of Bari, Italy
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PO:14:207 | Nailfold capillaroscopy in systemic lupus erythematosus: microvascular alterations and their clinical relevance Giulia Cassone1, Filippo Santoro2, Maria Grazia Malandra2, Bruno Biasi2, Elena Vanni2, Caterina Vacchi1, Alesandra Carobbio3, Dilia Giuggioli1|2. | 1Reumatologia, Azienda Ospedaliero-Universitaria Policlinico di Modena, Modena, Italy; 2Università di Modena e Reggio Emilia, Modena, Italy; 3Dipartimento di Scienze Mediche e Chirurgiche Materno-Infantili e dell'Adulto, Univeristà di Modena e Reggio Emilia, Modena, Italy.
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PO:15:216 | Safety and Efficacy of a single dose of Rituximab to manage Pregnancy-Related Severe Flare of Systemic Lupus Erythematosus: A Case Report Eugenio Capparelli1, Daniela Bompane1, Eleonora Zaccara1, Laura Castelnovo1, Antonio Tamburello1, Antonino Mazzone2, Paola Faggioli1 | 1UOC Reumatologia, ASST Ovest Milanese, Legnano, Milano, Italy; 2UOC Medicina Interna, ASST Ovest Milanese, Legnano, Milano, Italy
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S02:6 | Monocyte-Driven Inflammation and Inflammasome Activation in ANCA-Positive EGPA: Evidence of Persistent Immune Activation During Remission Chiara Baggio1, Luca Iorio1, Carlotta Boscaro2|3, Federica Davanzo1, Marta Tonello1, Mattia Albiero4, Andrea Doria1, Paolo Sfriso1, Roberto Padoan1, Francesca Oliviero1 | 1Rheumatology Unit, Department of Medicine, University of Padova, Italy; 2Department of Medicine, University of Padova, Italy; 3Veneto Institute of Molecular Medicine, Laboratory of Experimental Diabetology, Italy; 4Department of Surgery, Oncology, and Gastroenterology, University of Padova, Italy
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