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• PO:33:199 | Prevalence and clinical associations of antiphospholipid antibodies in patients with systemic sclerosis in the SPRING-SIR registry Antonio Tonutti^1|2, Ilaria Cavazzana³, Angela Ceribelli^1|2, Maria De Santis^1|2, Giacomo De Luca^4|5, Maria Grazia Lazzaroni³, Franco Franceschini³, Carlo Selmi^1|2, Valeria Riccieri⁶, Silvia Laura Bosello⁷, Fabio Cacciapaglia⁸, Veronica Codullo⁹, Francesca Ingegnoli¹⁰, Dilia Giuggioli¹¹, Rossella De Angelis¹², Clodoveo Ferri¹¹, Marco Matucci-Cerinic^4|5 | ¹Department of Biomedical Sciences, Humanitas Universityce Pieve Emanuele, Milan, Italy; ²Rheumatology and Clinical Immunology, IRCCS Humanitas Research Hospital Rozzano, Milan, Italy; ³Rheumatology and Clinical Immunology - ASST Spedali Civili Brescia - Department of Clinical and Experimental Sciences - Brescia, Italy; ⁴Vita-Salute San Raffaele University Milan, Italy; ⁵Unit of Immunology, Rheumatology, Allergy and Rare Diseases UnIRAR and INFLAGE Initiative, IRCCS San Raffaele Hospital Milan, Italy; ⁶University of Rome La Sapienza Rome, Italy; ⁷Catholic University of Sacred Heart Rome, Italy; ⁸LUM University Bari, Italy; ⁹Rheumatology Unit, Fondazione IRCCS Policlinico San Matteo Pavia, Italy; ¹⁰University of Milan Milan, Italy; ¹¹University of Modena and Reggio Emilia Modena, Italy; ¹²Politechnic University of Marche Ancona, Italy

  Società Italiana di Reumatologia

  18-03-2026

  https://doi.org/10.4081/reumatismo.2025.2376

  13

• PO:31:174 | Increased frequency of anti-RNA polymerase 3 antibodies in patients with systemic sclerosis and silicone breast implants: a multicentre study from the international European Scleroderma Trials and Research cohort Maria Grazia Lazzaroni¹, Yolanda Braun-Moscovici², Elda Piovani¹, Claudia Barison¹, Liala Moschetti¹, Veronica Batani³, Corrado Campochiaro³, Michal Tomcik⁴, Francesca Motta⁵, Maria De Santis⁵, Petros P. Sfikaki⁶, Masataka Kuwana⁷, Brigitte Granel⁸, Roberta Foti⁹, Virginia Berlingiero¹⁰, Joana Caetano¹¹, Yannick Allanore¹², Alexandra Balbir-Gurman², Marco Matucci Cerinic³, Franco Franceschini¹, Paolo Airò¹. | ¹ASST Spedali Civili of Brescia, University of Brescia, Brescia, Italy; ²Rambam Health Care Campus, Rappaport Faculty of Medicine, Technion-Israeli Institute of Tecnology, Haifa, Israel; ³Vita-Salute San Raffaele University, San Raffaele Hospital, Milano, Italy; ⁴Institute of Rheumatology, Praga, Czech Republic; ⁵IRCCS Humanitas Research Hospital; Humanitas University, Milano, Italy; ⁶Joint Rheumatology Program, Medical School, National Kapodistrian University of Athens Atene GREECE; ⁷Nippon Medical School Hospital Tokyo Japan; ⁸Hôpital Nord de Marseille; Aix-Marseille Université Marsiglia France; ⁹AOU Policlinico G. Rodolico San Marco, Catania, Italy; ¹⁰Azienda Ospedaliera Universitaria Senese, Siena, Italy; ¹¹Fernando Fonseca Hospital, Amadora, Portugal; ¹²Université Paris Cité, Cochin Hospital, Parigi, France.

  Società Italiana di Reumatologia

  25-11-2025

  https://doi.org/10.4081/reumatismo.2025.2075

  135

• PO:31:168 | Risk factors for cancer in systemic sclerosis, impact on disease phenotype and prognosis, and proposal of machine learning-based personalized screening strategies: insights from an EUSTAR study Antonio Tonutti^1|2, Francesca Motta^1|2, Stefano Erba^1|2, Britta Maurer³, Cristiana Sieiro Santos³, Duygu Temiz Karadag³, Elena Rezus³, Elisabetta Zanatta³, Fabiola Atzeni³, Francesco Benvenuti³, Gabor Kumanovics³, Gabriella Szucs³, Gianluca Moroncini³, Gonçalo Boleto³, Leila Caillault³, Lilian Maria Lopez Nunez³, Masataka Kuwana³, Massimiliano Limonta³, Maurizio Cutolo³, Oliver Distler³, Radim Bevcar³, Roberto Giacomelli³, Rossella De Angelis³, Serena Guiducci³, Stefano Stano³, Valeria Riccieri³, Yasser El Miedany³, Sophie Blaise³, Carlo Selmi^1|2, Maria De Santis^1|2 | ¹Department of Biomedical Sciences, Humanitas University Pieve Emanuele, Milan, Italy; ²Rheumatology and Clinical Immunology, IRCCS Humanitas Research Hospital Rozzano, Milan, Italy; ³EUSTAR collaborators EUSTAR * OTHER

  Società Italiana di Reumatologia

  18-03-2026

  https://doi.org/10.4081/reumatismo.2025.2367

  15

• PO:32:187 | AI-assisted reading outperforms visual scoring of pulmonary CT scans to predict interstitial lung disease progression in systemic sclerosis Francesca Motta¹, Antonio Tonutti¹, Federica Catapano², Gianluca Sellaro², Francesco Amati³, Anna Stainer³, Calogero Messana², Stefano Erba¹, Stefano Aliberti³, Marco Francone², Carlo Selmi¹, Maria De Santis¹ | ¹Humanitas University and IRCCS Humanitas Research Hospital, Department of Rheumatology and Clinical Immunology Rozzano, Milan, Italy; ²IRCCS Humanitas Research Hospital, Department of Radiology Rozzano, Milan, Italy; ³IRCCS Humanitas Research Hospital, Respiratory Unit Rozzano, Milan, Italy

  Società Italiana di Reumatologia

  18-03-2026

  https://doi.org/10.4081/reumatismo.2025.2373

  15

• PO:31:161 | First-line diagnostic tests to intercept primary heart involvement in systemic sclerosis: clinical associations from the SPRING-SIR registry Antonio Tonutti^1|2, Francesca Motta^1|2, Rossella De Angelis³, Valeria Riccieri⁴, Silvia Laura Bosello⁵, Fabio Cacciapaglia⁶, Veronica Codullo⁷, Giacomo De Luca⁸, Francesca Ingegnoli⁹, Dilia Giuggioli¹⁰, Clodoveo Ferri¹⁰, Marco Matucci-Cerinic⁸, Carlo Selmi^1|2, Maria De Santis^1|2 | ¹Department of Biomedical Sciences, Humanitas University Pieve Emanuele, Milan, Italy; ²Rheumatology and Clinical Immunology, IRCCS Humanitas Research Hospital Rozzano, Milan, Italy; ³Università Politecnica delle Marche Ancona, Italy; ⁴Università degli Studi di Roma La Sapienza Roma, Italy; ⁵Università Cattolica del Sacro Cuore Roma, Italy; ⁶Università degli Studi di Bari Aldo Moro Bari, Italy; ⁷Reumatologia, Fondazione IRCCS Policlinico San Matteo Pavia, Italy; ⁸Università Vita-Salute San Raffaele Milano, Italy; ⁹Università degli Studi di Milano, Italy; ¹⁰Università degli Studi di Modena e Reggio Emilia, Italy

  Società Italiana di Reumatologia

  18-03-2026

  https://doi.org/10.4081/reumatismo.2025.2366

  26