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PO:35:218 | Switching the dose of mepolizumab in patients with Eosinophilic Granulomatosis with Polyangiitis (EGPA): a European retrospective multicentre real-world study Edoardo Biancalana1, Irene Mattioli1, Emanuele Chiara2, Danilo Malandrino1, Maria Canfora1, Palmerini Miki1, Maria Paola Lisi1, Michela Gasparotto3, Paola Tomietto3, Maria Letizia Urban1, Giacomo Bagni1, Elena Silvestri1, Alessandra Bettiol3, Augusto Vaglio3, Giacomo Emmi2 | 1Department of Experimental and Clinical Medicine, University of Florence Firenze, Italy; 2Department of Medical, Surgery and Health Sciences, University of Trieste Trieste, Italy; 3Clinical Medicine and Rheumatology Unit, Cattinara University Hospital, Trieste, Trieste, Italy; 4Department of Biomedical, Experimental and Clinical Sciences Mario Serio, University of Florence Firenze, Italy
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PO:35:226 | Red flags raising suspicion of Eosinophilic Granulomatosis with Polyangiitis (EGPA): results from the European EGPAware Delphi study Gabriele Brembilla1, Bernhard Hellmich2|3, Apostolos Bossios4|5, Chistian Domingo-Ribas6|7, Giacomo Emmi8, Cristina Ponte9|10, Maria Roser Solans-Laque11, Íñigo Jesus Rúa-Figueroa12, Augusto Vaglio13, Dimitrios Vassilopoulos14, Konstantina Kallinikou15, Benjamin Terrier16 | 1GSK Verona, Italy; 2Medius Klinik Kirchheim Kirchheim unter Teck Germany; 3Teaching Hospital of the University of Tübingen Tübingen Germany; 4Karolinska University Hospital Stockholm, Sweden; 5Karolinska Institutet Solna, Sweden; 6Parc Taulí University Hospital. Parc Taulí Research and Innovation Institute I3PT-CERCA Barcelona Spain; 7Department of Medicine, Universitat Autònoma de Barcelona UAB Barcelona Spain; 8University of Trieste, UNITS, Trieste, Italy; 9Santa Maria Hospital Lisbon, Portugal; 10Lisbon Academic Medical Center Lisbon, Portugal; 11Vall d'Hebron University Hospital Barcelona Spain; 12Gran Canaria Doctor Negrín Hospital Las Palmas de Gran Canaria Spain; 13University of Florence Florence, Italy; 14National and Kapodistrian University of Athens School of Medicine Athens, Greece; 15GSK Athens, Greece; 16Cochin Hospital Paris, France
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PO:35:219 | Real-world effectiveness of mepolizumab on gastrointestinal involvement in eosinophilic granulomatosis with polyangiitis and hypereosinophilic syndrome: a multicentre retrospective study Alessia Gatti1, Francesca Regola1, Giulia Fontana1, Mario Addrea Piga2, Gianluca Moroncini2, Palma Carlucci3, Angelo Vacca3, Paolo Delvino4, Enrico Heffler5, Emanuele Nappi5, Jakub Moll6, Laura Losappio6, Jan Schroeder6, Federica Davanzo7, Roberto Padoan7, Edoardo Conticini8, Paolo Cameli8, Greta Pacini9, Alvise Berti9, Lorenzo Vrola10, Paola Tomietto10, Luca Quartuccio11, Jan Willem Cohen Tervaert12, Sabrina Arnold13, Peter Lamprecht13, Florence Roufosse14, Ilaria Cavazzana1, Franco Franceschini1, Giacomo Emmi15, Paola Toniati1. | 1Rheumatology and Clinical Immunology Unit, ERN ReCONNET, ASST Spedali Civili of Brescia and University of Brescia, Italy, Brescia, Italy; 2Università Politecnica delle Marche and Azienda Ospedaliero Universitaria delle Marche, Ancona, Italy, Ancona, Italy; 3Section of Internal Medicine 'Guido Baccelli', DiMePRe-J, University of Bari 'Aldo Moro', Bari, Italy, Bari, Italy; 4Rheumatology Unit, IRCCS San Gerardo dei Tintori, Monza, Italy Monza Italy; 5Department of Biomedical Sciences, Humanitas University and Personalized Medicine, Asthma and Allergy IRCCS Humanitas, Milano, Italy; 6Division of Allergy and Clinical Immunology, ASST GOM Niguarda, Milan, Italy, Milano, Italy; 7Rheumatology Unit, Department of Medicine DIMED, University of Padua, Padova, Italy, Padova, Italy; 8University of Siena, Siena, Italy, Siena, Italy; 9Santa Chiara Hospital and University of Trento, Unit of Rheumatology, Trento, Italy Trento Italy; 10UCO Medicina Clinica, ASUGI, Cattinara Teaching Hospital, Trieste, Italy, Trieste, Italy; 11Division of Rheumatology, Department of Medicine DMED, University of Udine, Udine, Italy, Udine, Italy; 12University of Alberta, Edmonton, Alberta, Canada and Maastricht University, Maastricht, The Netherlands Maastricht The Netherlands; 13Department of Rheumatology and Clinical Immunology, University of Lübeck, Lübeck, Germany Lubeck Germany; 14Department of Internal Medicine, Hôpital Universitaire de Bruxelles - Erasme, Université Libre de Bruxelles, Belgium Brussels Belgium; 15Clinical Medicine and Clinical Immunology and Rheumatology Unit Cattinara University Hospital and University of Trieste, Trieste, Italy.
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PO:15:222 | Post-hoc analysis of the BeRLiSS-JS registry: efficacy of belimumab on thrombocytopenia Greta Hulej1, Margherita Zen1, Marisol Bracalenti1, Francesca Bottazzi2, Rossella De Angelis3, Giacomo Emmi4, Roberto Gerli5, Marcello Govoni6, Renato Lo Gullo7, Simone Negrini8, Luca Quartuccio9, Maurizio Rossini10, Carlo Salvarani11, Paola Tomietto4, Angelo Vacca12, Andrea Doria1, Luca Iaccarino1. | 1Università degli Studi di Padova, Padova, Italy; 2Università degli Studi di Pavia, Pavia, Italy; 3Università Politecnica delle Marche, Ancona, Italy; 4Università degli Studi di Trieste, Trieste, Italy; 5Università degli Studi Perugia, Perugia, Italy; 6Università degli Studi di Ferrara, Ferrara, Italy; 7Università degli Studi di Catania, Catania, Italy; 8Università degli Studi di Torino, Torino, Italy; 9Università degli Studi di Udine, Udine, Italy; 10Università degli Studi di Verona, Verona, Italy; 11Università degli Studi di Modena e Reggio Emilia, Modena, Italy; 12Università degli Studi di Bari .
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PO:19:279 | Predictors of proteinuria, amyloidosis and kidney failure in familial Mediterranean fever: data from the International AIDA Network Registry Jessica Sbalchiero1, Antonio Vitale1, Valeria Caggiano1, Abdurrahman Tufan2, Ezgi Batu3, Gaafar Ragab4, Seza Ozen3, Jurgen Sota1, Carla Gaggiano1, Ali Sahin5, Petros Sfikakis6, Francesca Li Gobbi7, Giacomo Emmi8, Jose Rodriguez9, Piero Ruscitti10, Paolo Sfriso11, Ewa Szewczyk12, Giuseppe Lopalco13, Alberto Balistreri14, Claudia Fabiani15, Bruno Frediani1, Luca Cantarini1 | 1Department of Medical Sciences, Surgery and Neurosciences, University of Siena, Siena, Italy; 2Department of Internal Medicine, Division of Rheumatology, Gazi University Hospital Ankara, Turkey; 3Division of Pediatric Rheumatology, Department of Pediatrics, Hacettepe University School of Medicine Ankara, Turkey; 4Internal Medicine Department, Rheumatology and Clinical Immunology Unit, Faculty of Medicine, Cairo University Giza, Egypt; 5Division of Rheumatology, Department of Internal Medicine, Sivas Cumhuriyet University Medical Faculty Sivas, Turkey; 6Joint Academic Rheumatology Program, Medical School, National and Kapodistrian University of Athens Athens, Greece; 7Rheumatology Unit, Hospital S. Giovanni di Dio, Azienda USL-Toscana Centro Florence, Italy; 8Clinical Medicine and Rheumatology Unit, Cattinara University Hospital Trieste, Italy; 9Department of Autoimmune Diseases, Institut Investigacions Biomediques August Pi I Sunyer, University of Barcelona Barcelona Spain; 10Rheumatology Unit, Department of Biotechnological and Applied Clinical Sciences, University of L'Aquila, L'Aquila, Italy; 11Rheumatology Unit, Department of Medicine, University of Padua Padua, Italy; 127Department of Internal Medicine, Pneumonology, Allergology, Clinical Immunology and Rare Diseases, Military Institute o Warsaw, Poland; 13Department of Precision and Regenerative Medicine and Ionian Area DiMePRe-J Policlinic Hospital, University of Bari Bari, Italy; 14Bioengineering and Biomedical Data Science Lab, Department of Medical Biotechnologies, University of Siena Siena, Italy; 15Ophthalmology Unit, Department of Medicine, Surgery and Neurosciences, University of Siena Siena, Italy
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PO:21:026 | Identifying patient profiles to personalize care and improve quality of life in italian EGPA patients Francesca Torracca1, Roberto Padoan2, Giacomo Emmi3|4, Lara Bernardi5, Maria Rosaria Mollo5, Omar Shalby5, Fabio Tedone6, Davide Cafiero6, Eugenia Durante1 | 1APACS APS ETS - Associazione Pazienti Sindrome di Churg Strauss EGPA Arosio, Italy; 2Rheumatology Unit, Department of Medicine DIMED, University of Padua, Italy; 3Department of Medical, Surgical and Health Sciences, University of Trieste, Italy; 4Clinical Medicine Rheumatology Unit, Cattinara University Hospital, Trieste, Italy; 5GlaxoSmithKline Medical Department Verona, Italy; 6Helaglobe SRL Firenze, Italy
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CO:11:3 | Belimumab for lupus nephritis patients with poor kidney function: a post-hoc analysis of the bliss-ln trial Giacomo Emmi1|2, Ersilia Lucenteforte3, Giorgio Limoncella3, Emanuele Chiara1|2, Marta Calatroni4|5, Gabriella Moroni4|5 | 1Clinical Medicine and Rheumatology Unit, Cattinara University Hospital, Trieste, Italy; 2Department of Medical, Surgical and Health Sciences, University of Trieste, Trieste, Italy; 3Department of Statistics, Informatics and Applications Giuseppe Parenti, University of Florence, Florence, Italy; 4Department of Biomedical Sciences, Humanitas University, Pieve Emanuele, Milan, Italy; 5Nephrology and Dialysis Division, IRCCS Humanitas Research Hospital, Milan, Italy
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CO:06:3 | Clinical and laboratory markers for distinguishing VEXAS from Schnitzler's syndrome in male patients with skin involvement: insights from the International AIDA Network Registries Valeria Caggiano1, Jessica Sbalchiero1, Micol Frassi2, Andrea Hinojosa-Azaola3, Francesca Crisafulli2, Franco Franceschini2, Paolo Sfriso4, Sara Bindoli4, José Hernández-Rodríguez5, Henrique A. Mayrink Giardini6, Giuseppe Lopalco7, Florenzo Iannone7, Ombretta Viapiana8, Amato De Paulis9, Lorenzo Dagna10, Antonio Gidaro11, Serena Bugatti12, Matteo Piga13, Fabrizio Conti14, Rosetta Vitetta15, Cecilia Chighizola16, Marcello Govoni17, Giacomo Emmi18, Paola Triggianese19, Carmelo Gurnari19, Bruno Frediani1, Claudia Fabiani1, Luca Cantarini1, Antonio Vitale1, for the AIDA Network1 | 1Department of Medical Sciences, Surgery and Neurosciences, University of Siena; 2University of Brescia, Italy; 3Department of Immunology and Rheumatology, Mexico City, Mexico; 4Rheumatology Unit, University of Padova, Italy; 5Clinical Unit of Autoinflammatory Diseases, Hospital Clínic of Barcelona, Spain; 6Rheumatology Division, Universidade de São Paulo, Brazil; 7University of Bari; 8Rheumatology Unit, University and Azienda Ospedaliera Universitaria Integrata of Verona; 9University of Napoli "Federico II"; 10Università Vita-Salute San Raffaele, Milano; 11Luigi Sacco Hospital, University of Milano; 12Università di Pavia; 13University and AOU of Cagliari; 14AOU Policlinico Umberto I, Sapienza University of Rome; 15Unit of Rheumatology, ASL Sant' Andrea Hospital, Vercelli; 16University of Milano; 17Azienda Ospedaliero-Universitaria S. Anna, Ferrara; 18University of Trieste; 19University of Rome-Tor Vergata, Rome, Italy.
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PO:14:197 | Safety of biologic and conventional immunosuppressants in an Italian cohort of patients with systemic lupus erythematosus: a longitudinal analysis from the Lupus Italian Registry pharmacoepidemiologic study promoted by the Italian Society of Rheumatology Davide Rozza1, Carlo Alberto Scirè1|2, Paola Conigliaro3, Giacomo Emmi4, Laura Coladonato6, Salvatore Scarpato7, Luca Iaccarino8, Serena Guiducci9, Giulia Pazzola10, Francesca Romana Spinelli11, Micol Frassi12, Ilaria Cavazzana12, Chiara Scirocco13, Valeria Orefice13, Immacolata Prevete13, Alessandra Bortoluzzi14, Marcello Govoni14, Elena Bartoloni15, Luca Moroni16, Giuseppe Alvise Ramirez16, Valentina Canti16, Giorgio Pettiti17, Maria Chiara Ditto18, Enrico Fusaro18, Marta Mosca19, Lorenzo Cavagna20, Fabrizio Conti11, Andrea Doria8, Gian Domenico Sebastiani13, Sperimentatori Gruppo Lire5 | 1Centro Studi della Società Italiana di Reumatologia, Milano; 2Dipartimento di Medicina e Chirurgia, Università degli Studi di Milano-Bicocca, Monza; 3Università di Roma Tor Vergata; 4Dipartimento di Scienze Mediche, Chirurgiche e della Salute, Università di Trieste; 5https://redcap.reumatologia.it/surveys/?s=LWL7WJM4KHDR97CC; 6Dip di Medicina di Precisione e Rigenerativa e area Jonica, Bari; 7Azienda Sanitaria Locale ASL Salerno; 8Università degli Studi di Padova; 9SOD Reumatologia, Dipartimento di Medicina Sperimentale e Clinica, Università degli Studi di Firenze; 10Arcispedale Santa Maria Nuova Reggio Emilia; 11Università degli Studi di Roma La Sapienza; 12Spedali Civili di Brescia; 13Azienda Ospedaliera San Camillo Forlanini, Roma; 14Azienda Ospedaliera Universitaria Sant'Anna, Ferrara; 15SC Reumatologia, Dipartimento di Medicina e Chirurgia, Università di Perugia; 16IRCCS Ospedale San Raffaele, Milano; 17Azienda Ospedaliera S. Croce e Carle, Cuneo; 18AOU Citta' della Salute e della Scienza di Torino; 19AOU Santa Chiara, Pisa; 20Università di Pavia, Italy
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PO:26:092 | Early antiproteinuric effect of voclosporine in patients with lupus nephritis in real life setting: preliminary results from the VoRLiSS (Voclosporine in Real Life Setting Study) Aurora Di Gregorio1, Marta Calatroni2, Marco Allinovi3, Alessandra Bortoluzzi4, Giorgio Buscetta5, Rossella De Angelis6, Ginevra De Marchi7, Giacomo Emmi8, Pasquale Esposito9, Paride Fenaroli10, Micaela Fredi11, Giovanni Orsolini12, Giulia Pazzola13, Domenico Santoro14, Andrea Doria1, Gabriella Moroni2, Luca Iaccarino1 | 1Azienda Ospedaliera Universitaria Padova, Italy; 2Ospedale IRCCS Humanitas Milano, Italy; 3Azienda Ospedaliero Universitaria Careggi Firenze, Italy; 4Azienda Ospedaliero Universitaria di Ferrara, Italy; 5Policlinico Universitario Paolo Giaccone Palermo, Italy; 6Università Politecnica delle Marche Ancona, Italy; 7Università di Udine, Italy; 8Università di Trieste, Italy; 9Università di Genova, Italy; 10Unità di Nefrologia AUSL IRCCS di Reggio Emilia, Italy; 11Università di Brescia, Italy; 12Università di Verona Verona, Italy; 13Università di Reggio Emilia, Italy; 14Azienda Ospedaliera Universitaria G. Martino di Messina, Italy
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