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• CO:02:1 | Frequency and predictors of disease progression in contemporary seronegative undifferentiated arthritis in a treated-to-target early arthritis clinic Elena Manna¹, Ludovico De Stefano^1|2, Domenico Sorace^1|2, Jacopo Pelizza^1|2, Blerina Xoxi^1|2, Antonio Manzo^1|2, Carlomaurizio Montecucco^1|2, Serena Bugatti^1|2. | ¹Department of Internal Medicine and Therapeutics, University of Pavia; ²Division of Rheumatology, IRCCS Policlinico San Matteo Foundation, Pavia, Italy

  Società Italiana di Reumatologia

  25-11-2025

  https://doi.org/10.4081/reumatismo.2025.1965

  202

• S05:6 | Prevalence of osteoporosis and bone mineral metabolism disorders in an Italian cohort of patients with microcrystalline arthritis: results from the PREMIA observational study of the Italian Society of Rheumatology Silvia Grignaschi¹, Sonia Farah², Silvia Balduzzi¹, Bernd Raffeiner³, Carlomaurizio Montecucco⁴, Fausto Salaffi², Enrico Selvi⁵, Annamaria Iagnocco⁶, Fabiola Atzeni⁷, Serena Guiducci⁸, Rosario Foti⁹, Maria Manara¹⁰, Marcello Govoni¹¹, Carlo Selmi¹², Francesca Oliviero¹³, Roberta Ramonda¹³ | ¹ASST Pavia; ²Ospedale Carlo Urbani Jesi Italy; ³Azienda Sanitaria dell'Alto Adige, Bolzano; ⁴IRCCS Fondazione Policlinico San Matte, Pavia; ⁵AOU Senese, Siena; ⁶Ospedale MAuriziano, Torino; ⁷Università di Messina; ⁸AOU Careggi, Firenze; ⁹AOU Policlinico G. Rodolico, Catania; ¹⁰ASST Gaetano Pini-CTO Milano; ¹¹AUSL Ferrara; ¹²Humanitas San Pio X, Milano; ¹³AOU Padova, Italy

  Società Italiana di Reumatologia

  25-11-2025

  https://doi.org/10.4081/reumatismo.2025.2228

  152

• PO:32:176 | Outcomes of upfront combination vs monotherapy with rituximab or mycophenolate mofetil for systemic sclerosis interstitial lung disease: results from a European Scleroderma Trials and Research cohort study Devis Benfaremo¹, Corrado Campochiaro², Gábor Kumánovics³, Christina Bergmann⁴, Elisabetta Zanatta⁵, David Launay⁶, Serena Guiducci⁷, Mickael Martin⁸, Carolina De Souza Müller⁹, Carlomaurizio Montecucco¹⁰, Luc Mouthon¹¹, Gabriella Szucs¹², Kastriot Kastrati¹³, Marie-Elise Truchetet¹⁴, Madelon Vonk¹⁵, Francesco Del Galdo¹⁶, Marco Matucci-Cerinic², Gianluca Moroncini¹, Yannick Allanore¹⁷. | ¹Department of Clinical and Molecular Sciences, Marche Polytechnic University, Marche University Hospital, Ancona, Italy; ²Vita-Salute San Raffaele University, San Raffaele Hospital, Milano, Italy; ³University of Pécs, Department Of Rheumatology And Immunology, Pécs, Hungary; ⁴University Hospital Erlangen, Department Internal Medicine 3, Erlangen, Germany; ⁵Padova University Hospital, Rheumatology Unit, Padova, Italy; ⁶Univ. Lille, Inserm, CHU Lille, Department of Internal Medicine and Clinical Immunology, Lille, France; ⁷University of Florence, Azienda Ospedaliera Universitaria Careggi, Firenze, Italy; ⁸Poitiers University Hospital, Department of Internal Medicine Poitiers France; ⁹Hospital de Clinicas da Universidade Federal do Parana Curitiba Brazil; ¹⁰Università di Pavia e IRCCS Fondazione Policlinico S. Matteo, Pavia, Italy; ¹¹Hôpital Cochin, Department of Internal Medicine, Paris, France; ¹²University of Debrecen, Faculty of Medicine, Department of Rheumatology, Debrecen, Hungary; ¹³Medical University of Vienna, Department of Medicine III, Division of Rheumatology, Vienna, Austria; ¹⁴CHU de Bordeaux, Rheumatology department, Bordeaux, France; ¹⁵Radboudumc, Department of Rheumatology Nijmegen The Netherlands; ¹⁶Leeds Raynauds and Scleroderma Program, NIHR Biomedical Research Centre, Leeds, United Kingdom; ¹⁷Université Paris Cité, Cochin Hospital, Rheumatology Department, Paris, France.

  Società Italiana di Reumatologia

  25-11-2025

  https://doi.org/10.4081/reumatismo.2025.2077

  174

• PO:31:175 | Characterizing gastrointestinal involvement in systemic sclerosis: insights from the national systemic sclerosis progression investigation registry of the Italian Society of Rheumatology Francesco Bonomi¹, Cosimo Bruni^1|2, Silvia Laura Bosello³, Fabio Cacciapaglia^4|5, Corrado Campochiaro⁶, Roberto Caporali⁷, Veronica Codullo⁸, Maria Antonietta D'Agostino³, Lorenzo Dagna⁶, Rossella De Angelis⁹, Giacomo De Luca⁶, Dilia Giuggioli¹⁰, Serena Guiducci¹, Florenzo Iannone⁴, Francesca Ingegnoli⁷, Carlomaurizio Montecucco⁸, Valeria Riccieri¹¹, Clodoveo Ferri¹⁰, Marco Matucci Cerinic⁶, Silvia Bellando Randone¹. | ¹Scleroderma Unit, Division of Rheumatology AOUC, and Department of Experimental and Clinical Medicine, Uni. of Florence, Firenze, Italy; ²Department of Rheumatology, University Hospital Zurich, University of Zurich Zurigo Switzerland; ³UOC of Rheumatology and Clinical Immunology, Catholic University of the Sacred Heart, Fondazione Policlinico A. Gemelli, Roma, Italy; ⁴Rheumatology Unit, Department of Emergency Surgery and Organ Transplantations, University of Bari, Bari, Italy; ⁵Rheumatology Service, F. Miulli General Hospital - Department of Medicine and Surgery, LUM 'G. De Gennaro', Casamassima, Italy; ⁶Unit of Immunology, Rheumatology, Allergy and Rare Diseases and Inflammation, fibrosis and ageing initiative, UniSR, Milano, Italy; ⁷Division of Clinical Rheumatology, ASST Pini and Università degli studi di Milano, Milano, Italy; ⁸Department of Rheumatology, Policlinico San Matteo, Pavia, Italy; ⁹Rheumatology Unit, Department of Clinical and Molecular Sciences, Polytechnic University of Marche, Ancona, Italy; ¹⁰Rheumatology Unit, School of Medicine, University of Modena and Reggio Emilia, Modena, Italy; ¹¹Department of Rheumatology, Sapienza University of Rome, Roma, Italy.

  Società Italiana di Reumatologia

  25-11-2025

  https://doi.org/10.4081/reumatismo.2025.2076

  167

• PO:07:111 | Worsening of patient-reported outcomes is an early predictor of disease flare in patients with rheumatoid arthritis in course of treatment with conventional synthetic disease modifying anti-rheumatic drugs Ludovico De Stefano^1|2, Federica Sabatelli^1|2, Clelia Zampaglione^1|2, Blerina Xoxi², Antonio Manzo^1|2, Carlomaurizio Montecucco^1|2, Serena Bugatti^1|2. | ¹Department of Internal Medicine and Therapeutics, University of Pavia, Pavia, Italy; ²Division of Rheumatology, IRCCS Policlinico San Matteo Foundation, Pavia, Italy.

  Società Italiana di Reumatologia

  25-11-2025

  https://doi.org/10.4081/reumatismo.2025.2022

  164

• PO:06:083 | Clinical characteristics and outcomes of late- and young-onset rheumatoid arthritis in relation to autoantibody status Federica Sabatelli^1|2, Ludovico De Stefano^1|2, Clelia Zampaglione^1|2, Lisa Bergianti^1|2, Blerina Xoxi^1|2, Antonio Manzo^1|2, Carlomaurizio Montecucco^1|2, Serena Bugatti^1|2. | ¹Department of Internal Medicine and Therapeutics, University of Pavia, Pavia; ²Division of Rheumatology, IRCCS Policlinico San Matteo Foundation, Pavia, Italy.

  Società Italiana di Reumatologia

  25-11-2025

  https://doi.org/10.4081/reumatismo.2025.2015

  139

• PO:06:092 | Early achievement of remission confers better outcomes than low disease activity in both seropositive and seronegative patients with new-onset rheumatoid arthritis Clelia Zampaglione^1|2, Ludovico De Stefano^1|2, Federica Sabatelli^1|2, Alessio D'Isanto^1|2, Blerina Xoxi^1|2, Antonio Manzo^1|2, Carlomaurizio Montecucco^1|2, Serena Bugatti^1|2. | ¹Department of Internal Medicine and Therapeutics, University of Pavia, Pavia; ²Division of Rheumatology, IRCCS Policlinico San Matteo Foundation, Pavia, Italy.

  Società Italiana di Reumatologia

  25-11-2025

  https://doi.org/10.4081/reumatismo.2025.2017

  166