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PO:01:011 | Achievement of Remission Defined by Absence of Objective Signs of Inflammation Versus ASDAS ID in Patients with Active Axial Spondyloarthritis Treated with Bimekizumab: 52-Week Results from Two Phase 3 Studies Lianne S Gensler1, Helena Marzo-Ortega2, Vanessa Taieb3, Diana Voiniciuc4, Alexander Marten5, George Stojan6, Mindy Kim6, Paolo Marsico7, Martin Rudwaleit8 | 1Department of Medicine/Rheumatology, University of California San Francisco, USA; 2NIHR Leeds Biomedical Research Centre, University of Leeds Leeds, United Kingdom; 3UCB Colombes, France; 4UCB Slough, United Kingdom; 5UCB Monheim am Rhein Germany; 6UCB Atlanta, USA; 7UCB Milan, Italy; 8University of Bielefeld, Klinikum Bielefeld Bielefeld Germany
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PO:13:189 | Greater impact of psoriatic arthritis in females: is this mediated primarily by disease activity? Roberta Masnata1, Valentina Boni1, Giusy Peluso1, Giulia Calabrese1, Enrico De Lorenzis1, Gerlando Natalello1, Maria Antonietta D'Agostino1, Augusta Ortolan1. | 1UOC Reumatologia e Immunologia Clinica- Fondazione Policlinico Agostino Gemelli IRCCS-Università Cattolica Sacro Cuore, Roma, Italy.
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CO:09:4 | Erosive hand osteoarthritis: the impact of comorbidities in the context of joint disease Sara Bindoli1, Clarissa Benvoluti1, Giacomo Cozzi1, Marta Favero1, Mariagrazia Lorenzin1, Andrea Doria1, Paolo Sfriso1, Roberta Ramonda1. | 1UOC Reumatologia, Dipartimento di Medicina , Università degli studi di Padova, Italy
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PO:11:171 | Subcutaneous tocilizumab use in a young-onset mixed connective tissue disease patient with multiple treatment failures Rhaysa Araujo Mousinho1, Elide Lupi2, Massimiliano Limonta2 | 1Clinica di Reumatologia, Dipartimento di Medicina and 2Istituto di Anatomia Patologica, Dipartimento di Medicina di Laboratorio, Osp. S. M. della Misericordia, Università di Udine, Italy
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PO:33:203 | Efficacy and safety of rituximab in eosinophilic fasciitis: report of three cases and systematic literature review Andrea Benini1, Beatrice Moccaldi1, Marco Binda1, Anna Cuberli1, Mariangela Favaro1, Andrea Doria1, Elisabetta Zanatta1 | 1UOC Reumatologia, Azienda Ospedale, Università di Padova, Italy
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PO:07:095 | Clinical impact of therapeutic modification following changes in AIFA reimbursement criteria for JAK inhibitors in patients with RA in remission/low disease activity: analysis of the multicenter JAK-SWAP RER study in Emilia-Romagna Marta Raschella1, Giulia Furia1, Martina Di Nunzio1, Francesco Luca Renzullo2, Francesco Girelli2, Federica Pignatti3, Francesco Ursini3, Licia Vultaggio4, Pierluigi Cataleta4, Elena Bravi5, Eugenio Arrigoni5, Francesca Bergossi6, Enrica Vandelli7, Massimo Reta6|7, Viola Magnani8, Andreina Manfredi8|9, Giuseppe Germanò8, Alessandra Bortoluzzi1, Marcello Govoni1, Ettore Silvagni1 | 1Unità Operativa Complessa di Reumatologia, Dipartimento di Scienze Mediche, Università degli Studi di Ferrara e Azienda Ferrara; 2UOS Reumatologia, Ospedale GB Morgagni, Forlì; 3UOC Reumatologia, Istituto ortopedico Rizzoli, Bologna; 4UO Reumatologia, AUSL Romagna Ospedale di Ravenna; 5UO Reumatologia, Azienda USL di Piacenza; 6Reumatologia Osp. Maggiore, Bologna; 7UO Medicina Interna ad Indirizzo Reumatologico Interaziendale SC AUSL Bologna, IRCCS Policlinico di SantOrsola, Bologna; 8U.O Reumatologia, Santa Maria Nuova di Reggio Emilia; 9Università degli studi di Modena e Reggio Emilia, Italy
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PO:01:014 | Differential inflammatory responses of CD14+ and CD14– synoviocytes in psoriatic arthritis: implications for pathogenesis and targeted therapies Monia Maccaferri1, Monica Montanari2, Francesco Zambianchi3|4, Carlo Salvarani1|5, Elisa Pignatti1|4 | 1Dipartimento CHIMOMO; 2Dipartimento di Scienze e Vita; 3Dipartimento SMECHIMAI Università di Modena e Reggio Emilia; 4Azienda Ospedaliero Universitaria di Modena; 5Struttura Complessa di Reumatologia, Azienda Unità Sanitaria Locale di Reggio Emilia-IRCCS, Italy
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PO:08:117 | Association between the use of oral contraceptives and the development of rheumatoid arthritis: a systematic review and meta-analysis Annalisa Marino1, Damiano Currado1|2, Onorina Berardicurti1|2, Marta Vomero2, Lyubomyra Kun1, Letizia Pia Di Corcia2, Erika Corberi2, Francesca Trunfio2, Francesca Saracino2, Ludovica Lamberti2, Leonardo Frasca2, Angelo Battista3, Marta Alfano4, Silvia Schiavone5, Roberto Giacomelli1|2, Luca Navarini1|2. | 1Clinical and Research Section of Rheumatology and Clinical Immunology, Fondazione Campus Bio-Medico, Roma; 2Rheumatology and Clinical Immunology, Department of Medicine, University of Rome Campus Biomedico, School of Medicine, Roma; 3Department of Maternal Science, Paediatric Emergency Service, Sapienza University of Rome, Roma; 4Department of Experimental Medicine, Sapienza University of Rome, Roma; 5Department of Orthopaedics and Traumatology, Policlinico Tor Vergata Foundation, Roma, Italy
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PO:15:221 | Proteins upregulated in thrombotic antiphospholipid syndrome link to platelet function in contrast with non-antiphospholipid-related thrombosis: insights from two systematic reviews Silvia Mancuso1, Claudia Ciancarella1, Luca Rapino1, Simona Truglia1, Cristiano Alessandri1, Fabrizio Conti1. | 1Dipartimento di Scienze Cliniche Internistiche, Anestesiologiche e Cardiovascolari - Rheumatology Unit, Sapienza Univers, Roma, Italy.
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CO:04:1 | Bone properties and biomechanics in patients with psoriatic disease: a cross-sectional study with high-resolution peripheral quantitative computed tomography Anna Piccinelli1, Francesco Bellinato2, Francesco Pollastri1, Francesco Giorgio1, Martina Teoni1, Angelo Fassio1, Camilla Benini1, Carmela Dartizio1, Mattia Tugnolli1, Davide Gatti1, Maurizio Rossini1, Ombretta Viapiana1, Paolo Gisondi2, Giovanni Adami1. | 1Rheumatology Unit, University of Verona; 2Dermatology Unit, University of Verona, Italy
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PO:19:287 | Cardiac involvement in Still’s disease: a challenge in differential diagnosis Ludovica Manisera1, Martina Dodaro2, Giuseppe Norcia3, Angelica Gattamelata4, Nicola Galea5, Concetta Torromeo6, Gaetano Tanzilli7, Fabrizio Conti8, Roberta Priori9 | 1Dipartimento di Scienze Cliniche, Internistiche, Anestesiologiche e Cardiovascolari, Università degli Studi di Roma La Sapienza, Roma; 2Dipartimento di Medicina Traslazionale e di Precisione, Università degli Studi di Roma La Sapienza, Roma; 3Dipartimento di Medicina Molecolare, Università degli Studi di Roma La Sapienza, Roma, Italy
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PO:25:079 | Anifrolumab in refractory dermatomyositis: a case report Chiara Calabrese1, Corrado Campochiaro1|2, Giacomo De Luca 1|2, Veronica Batani1, Marco Matucci-Cerinic1|2, Lorenzo Dagna 1|2 | 1Dipartimento di Reumatologia e Scienze Mediche, ASST Centro Specialistico Ortopedico Traumatologico Gaetano Pini-CTO Milano; 2Università degli Studi di Milano, Dipartimento di Fisiopatologia Medico-Chirurgica e Trapianti, Milano, Italy
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PO:32:183 | Innovative use of integra dermal regeneration template on systemic sclerosis digital ulcers: a case report Elena Vanni1, Martina Orlandi1|2, Amelia Spinella2, Valentina Pinto3, Massimo Pinelli3, Dilia Giuggioli1|2 | 1Reumatologia, Università di Modena e Reggio Emilia; 2Reumatologia, Azienda Ospedaliero-Universitaria Policlinico di Modena; 3Chirurgia Plastica, Università di Modena e Reggio Emilia e Azienda Ospedaliero-Universitaria, Policlinico di Modena, Italy
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PO:08:121 | Correlation between SENS score and perceived disability in a monocentric cohort of patients affected by rheumatoid arthritis: preliminary analysis of 209 patients Francesco Angius1, Nicoleta Anamari Costin1, Mattia Fadda1, Davide Corradini2, Mattia Congia2, Elisabetta Chessa2, Alberto Floris1, Matteo Piga1 -2, Alberto Cauli1 -2 | 1SC Reumatologia, Dipartimento di Scienze Mediche e Salute Pubblica, Università di Cagliari; 2SC Reumatologia, AOU Cagliari, Italy
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PO:03:033 | Low Uveitis Rates in Patients with Axial Spondyloarthritis or Psoriatic Arthritis Treated with Bimekizumab: Long-Term Results from Phase 2b/3 Trials Irene E Van Der Horst-Bruinsma1, Matthew A Brown2, Floris A Van Gaalen3, Nigil Haroon4, Lianne S Gensler5, Alexander Marten6, Myriam Manente7, George Stojan8, Thomas Vaux9, Katy White9, Atul Deodhar10, Nicola Boffini11, Martin Rudwaleit12 | 1Department of Rheumatology, Radboud University Medical Centre Nijmegen, The Netherlands; 2Genomics England London, United Kingdom; 3Department of Rheumatology, Leiden University Medical Center Leiden, The Netherlands; 4Department of Medicine/Rheumatology, University Health Network, Schroeder Arthritis Institute, University of Toronto Toronto, Canada; 5Department of Medicine/Rheumatology, University of California San Francisco, USA; 6UCB Monheim am Rhein Germany; 7UCB Braine-lAlleud, Belgium; 8UCB Atlanta, USA; 9UCB Slough, United Kingdom; 10Division of Arthritis and Rheumatic Diseases, Oregon Health and Science University Portland, USA; 11IRCCS Ospedale San Raffaele Milan, Italy; 12Klinikum Bielefeld, University of Bielefeld, Bielefeld, Germany
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PO:05:069 | Risankizumab efficacy in peripheral and axial involvement: monocentric experience Roberta Foti1, Ylenia Dal Bosco1, Giorgio Amato1, Elisa Visalli1, Francesco De Lucia1, Gabriella Paolí1, Rosario Foti1. | 1UOSD Reumatologia AOU Policlinico G. Rodolico-S. Marco, Catania, Italy.
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CO:06:2 | Deep immunophenotyping in patients with juvenile localized scleroderma reveals two distinct immunological endophenotypes Emiliano Marasco1, Angela Aquilani1, Rebecca Nicolai1, Ivan Caiello1, Fabrizio De Benedetti1. | 1Unità di Reumatologia, Ospdeale Pediatrico Bambino Gesù, Roma, Italy
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CO:11:4 | Unveiling frailty in active systemic lupus erythematosus in the modern era of rheumatology: first real-life use of the SLICC-FI in a cohort diagnosed after 2000 Angela Elia1, Dina Zucchi2, Michele Moretti1, Elena Elefante2, Chiara Cardelli1, Linda Carli2, Viola Signorini2, Chiara Stagnaro2, Chiara Tani1, Marta Mosca1. | 1U.O. di Reumatologia, Dipartimento di Medicina Clinica e Sperimentale, Università di Pisa; 2U.O Reumatologia, Azienza Ospedaliero Universitaria Pisana, Pisa, Italy
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PO:18:276 | Use of anifrolumab in the treatment of difficult-to-treat manifestations in systemic lupus erythematosus Antonella Grimaldi1, Giuseppe Alessandrini2, Laura Quarta1, Maria Rita Ricciardi1, Daniela Costanza1, Clara Minerba1, Eugenio Quarta1 | 1UOC Reumatologia Verona; 2Specialista Dermatologo in Libera Professione, Italy
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PO:38:285 | Cross-sectional analysis: interpretation of nonstatistically significant results in randomised controlled clinical trials in rehabilitation Caterina Mugnai1, Luca Falsiroli Maistrello2|3|4, Giacomo Fiacca3, Michele Perrucchini3, Noemi Corbetta3, Federico Amateis3, Stefano Salvioli3 | 1University of Ferrara; 2ULSS 9 Scaligera, Department of Physical Medicine and Rehabilitation, G. Fracastoro Hospital, San Bonifacio VR; 3Department of Neurosciences, Rehabilitation, Ophthalmology, Genetics, Maternal and Child Health, University of Genoa; 4School of Physiotherapy, Department of Neuroscience, Biomedicine and Movement, University of Verona, Italy
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PO:32:184 | Assessing the burden of Sars-Cov2 in systemic sclerosis-related interstitial lung disease patients: functional, clinical and therapeutic outcomes from an Italian cohort, a retrospective study Andrea Cito1, Greta Giulia Dipietrangelo1, Daniele V. A. Sabella1, Marco Fornaro1, Fabio Cacciapaglia1, Giuseppe Lopalco1, Florenzo Iannone1. | 1AOUC Policlinico di Bari - Reumatologia Universitaria, Bari, Italy.
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S13:6 | Investigating the intricate interplay between pulmonary functionality and advanced microangiopathy in very early diagnosis of systemic sclerosis Eugenio Capparelli1, Eleonora Zaccara1, Daniela Bompane1, Elisabetta Ricchiuto2, Giorgio Bonardi2, Laura Castelnovo1, Antonio Tamburello1, Antonino Mazzone3, Paola Faggioli1. | 1Rheumatology Unit; 2Pneumology Unit; 3Internal Medicine Unit, ASST Ovest Milanese, Legnano, Italy.
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