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PO:31:174 | Increased frequency of anti-RNA polymerase 3 antibodies in patients with systemic sclerosis and silicone breast implants: a multicentre study from the international European Scleroderma Trials and Research cohort Maria Grazia Lazzaroni1, Yolanda Braun-Moscovici2, Elda Piovani1, Claudia Barison1, Liala Moschetti1, Veronica Batani3, Corrado Campochiaro3, Michal Tomcik4, Francesca Motta5, Maria De Santis5, Petros P. Sfikaki6, Masataka Kuwana7, Brigitte Granel8, Roberta Foti9, Virginia Berlingiero10, Joana Caetano11, Yannick Allanore12, Alexandra Balbir-Gurman2, Marco Matucci Cerinic3, Franco Franceschini1, Paolo Airò1. | 1ASST Spedali Civili of Brescia, University of Brescia, Brescia, Italy; 2Rambam Health Care Campus, Rappaport Faculty of Medicine, Technion-Israeli Institute of Tecnology, Haifa, Israel; 3Vita-Salute San Raffaele University, San Raffaele Hospital, Milano, Italy; 4Institute of Rheumatology, Praga, Czech Republic; 5IRCCS Humanitas Research Hospital; Humanitas University, Milano, Italy; 6Joint Rheumatology Program, Medical School, National Kapodistrian University of Athens Atene GREECE; 7Nippon Medical School Hospital Tokyo Japan; 8Hôpital Nord de Marseille; Aix-Marseille Université Marsiglia France; 9AOU Policlinico G. Rodolico San Marco, Catania, Italy; 10Azienda Ospedaliera Universitaria Senese, Siena, Italy; 11Fernando Fonseca Hospital, Amadora, Portugal; 12Université Paris Cité, Cochin Hospital, Parigi, France.
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PO:07:096 | Safety of filgotinib in the treatment of rheumatoid arthritis: results from the multicentre SOFIA study Anna Giorgia Osele1, Matteo Filippini2, Eugenio Capparelli3, Eleonora Bruschi4, Bernd Raffeiner5, Silvano Bettio6, Mariangela Salvato1, Federico Arru7, Massimiliano Limonta4, Paola Faggioli3, Elda Piovani2, Eleonora Zaccara3, Alessandro Giollo1, Margherita Zen1 | 1UOC Reumatologia, Azienda Ospedale-Università di Padova; 2UO Reumatologia e Immunologia Clinica, ASST Spedali Civili, Brescia; 3UOC Ruematologia, ASST Ovest Milanese, Legnano MI; 4SSD Reumatologia, ASST Papa Giovanni XXIII, Bergamo; 5Dipartimento di Reumatologia, Ospedale di Formazione Paracelsus ASDAA-SABES, Bolzano; 6Medicina Generale Unità 1^, Centro Regionale per le Malattie Rare Immunologiche e Reumatologiche, Ospedale Universitario Treviso; 7UO Medicina, ASL 3 Nuoro, Italy
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PO:06:084 | Interstitial lung involvement in rheumatoid arthritis patients treated with abatacept: a prospective observational study Francesca Cozzini1|2, Andreina Manfredi2|3, Antonio Carletto4, Elisa Bellis5, Laura Cometi6, Vincenzo Venerito7, Caterina Vacchi8, Fabiola Atzeni9, Antonio Carriero10, Rosaria Foti11, Mariagrazia Catanoso3, Ennio Favalli12, Chiara Bazzani13, Arianna Belvedere3, Cecilia Burattini1, Andrea Morciano4, Annamaria Iagnocco5, Gemma Lepri6, Florenzo Iannone7, Antonio Pezzano9, Salvatore D'Angelo10, Valentina Cateni4, Serena Guiducci6, Marco Sebastiani1|14. | 1Ospedale Guglielmo da Saliceto, Piacenza, Italy; 2Università degli studi di Modena e Reggio Emilia, Modena, Italy; 3IRCCS Arcispedale Santa Maria Nuova, Reggio Emilia, Italy; 4AOUI, Università degli studi di Verona, Verona, Italy; 5A.O. Mauriziano di Torino, Università degli studi di Torino, Torino, Italy; 6AOU di Careggi, Università degli studi di Firenze, Firenze, Italy; 7AOU Policlinico di Bari, università degli studi di Bari Aldo Moro, Bari, Italy; 8AOU Policlinico di Modena, Modena, Italy; 9AOU Gaetano Martino, Università degli studi di Messina, Messina, Italy; 10Azienda Ospedaliera Regionale San Carlo, Potenza, Italy; 11AO Vittorio Emanuele, Catania, Italy; 12ASST Gaetano Pini, Milano, Italy; 13ASST Spedali Civili, Brescia, Italy; 14Università degli studi di Parma, Parma, Italy.
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PO:01:003 | Sex-based differences in 2 years treatment outcomes with b/ts-DMARDs in psoriatic arthritis: from real-world evidence to predictive modeling from the Gruppo Italiano Studio Early Arthritis (GISEA) prospective registry Simone Perniola1, Florenzo Iannone1, Francesco Paolo Cantatore2, Angelo Semeraro3, Leonardo Santo4, Roberto Gorla5, Alberto Cauli6, Roberto Felice Caporali7, Bruno Frediani8, Rosario Foti9, Fabrizio Conti10, Marco Sebastiani11, Maria Sole Chimenti12, Roberta Ramonda13, Fabiola Atzeni14, Maurizio Rossini15, Serena Bugatti16, Serena Guiducci17, Giovanni Lapadula1, Gianfranco Ferraccioli18, Francesca Romana Spinelli10, Elisa Gremese19. | 1Rheumatology Unit, DiMePReJ, University of Bari, Bari; 2Rheumatology Unit, Department of Medical and Surgical Sciences, Azienda Ospedaliero-Universitaria Policlinico Riuniti, Foggia; 3Rheumatology Unit, Martina Franca Hospital; 4Rheumatology Unit, ASL BT, P.O. Barletta; 5Rheumatology and Clinical Immunology Unit, ASST Spedali Civili of Brescia; 6Rheumatology Unit, Department of Medical Science and Public Health, University of Cagliari, Monserrato (CA); 7Rheumatology Unit, Dipartimento di Reumatologia e Scienze Mediche, ASST PINI-CTO, University of Milano, Milano; 8Rheumatology Unit, Azienda Ospedaliero Universitaria Senese, Siena; 9Rheumatology Unit, A.O.U. Policlinico S. Marco, Catania; 10Rheumatology Unit, Department of Clinical Internal, Anesthesiologic and CV Sciences, Sapienza University of Rome, Roma; 11Rheumatology Unit, AUSL Piacenza, University of Parma, Parma; 12Rheumatology, Department of Systems Medicine, University of Rome Tor Vergata, Roma; 13Rheumatology Unit, DIMED, University of Padua, Padova; 14Rheumatology Unit, Department of Experimental and Internal Medicine, University of Messina, Messina; 15Rheumatology Unit, Department of Medicine, University of Verona, Verona; 16Division of Rheumatology, Dept. of Internal Medicine and Therapy, Fondazione IRCCS Policlinico S. Matteo, University of Pavia, Pavia; 17Division of Rheumatology, Department of Experimental and Clinical Medicine, University of Firenze, Firenze; 18Department of Medicine, Catholic University of the Sacred Heart, Fondazione Policlinico Gemelli IRCCS, Roma; 19Rheumatology and Clinical Immunology, IRCCS Humanitas Research Hospital, Humanitas University, Rozzano (MI), Italy
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PO:14:197 | Safety of biologic and conventional immunosuppressants in an Italian cohort of patients with systemic lupus erythematosus: a longitudinal analysis from the Lupus Italian Registry pharmacoepidemiologic study promoted by the Italian Society of Rheumatology Davide Rozza1, Carlo Alberto Scirè1|2, Paola Conigliaro3, Giacomo Emmi4, Laura Coladonato6, Salvatore Scarpato7, Luca Iaccarino8, Serena Guiducci9, Giulia Pazzola10, Francesca Romana Spinelli11, Micol Frassi12, Ilaria Cavazzana12, Chiara Scirocco13, Valeria Orefice13, Immacolata Prevete13, Alessandra Bortoluzzi14, Marcello Govoni14, Elena Bartoloni15, Luca Moroni16, Giuseppe Alvise Ramirez16, Valentina Canti16, Giorgio Pettiti17, Maria Chiara Ditto18, Enrico Fusaro18, Marta Mosca19, Lorenzo Cavagna20, Fabrizio Conti11, Andrea Doria8, Gian Domenico Sebastiani13, Sperimentatori Gruppo Lire5 | 1Centro Studi della Società Italiana di Reumatologia, Milano; 2Dipartimento di Medicina e Chirurgia, Università degli Studi di Milano-Bicocca, Monza; 3Università di Roma Tor Vergata; 4Dipartimento di Scienze Mediche, Chirurgiche e della Salute, Università di Trieste; 5https://redcap.reumatologia.it/surveys/?s=LWL7WJM4KHDR97CC; 6Dip di Medicina di Precisione e Rigenerativa e area Jonica, Bari; 7Azienda Sanitaria Locale ASL Salerno; 8Università degli Studi di Padova; 9SOD Reumatologia, Dipartimento di Medicina Sperimentale e Clinica, Università degli Studi di Firenze; 10Arcispedale Santa Maria Nuova Reggio Emilia; 11Università degli Studi di Roma La Sapienza; 12Spedali Civili di Brescia; 13Azienda Ospedaliera San Camillo Forlanini, Roma; 14Azienda Ospedaliera Universitaria Sant'Anna, Ferrara; 15SC Reumatologia, Dipartimento di Medicina e Chirurgia, Università di Perugia; 16IRCCS Ospedale San Raffaele, Milano; 17Azienda Ospedaliera S. Croce e Carle, Cuneo; 18AOU Citta' della Salute e della Scienza di Torino; 19AOU Santa Chiara, Pisa; 20Università di Pavia, Italy
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PO:35:219 | Real-world effectiveness of mepolizumab on gastrointestinal involvement in eosinophilic granulomatosis with polyangiitis and hypereosinophilic syndrome: a multicentre retrospective study Alessia Gatti1, Francesca Regola1, Giulia Fontana1, Mario Addrea Piga2, Gianluca Moroncini2, Palma Carlucci3, Angelo Vacca3, Paolo Delvino4, Enrico Heffler5, Emanuele Nappi5, Jakub Moll6, Laura Losappio6, Jan Schroeder6, Federica Davanzo7, Roberto Padoan7, Edoardo Conticini8, Paolo Cameli8, Greta Pacini9, Alvise Berti9, Lorenzo Vrola10, Paola Tomietto10, Luca Quartuccio11, Jan Willem Cohen Tervaert12, Sabrina Arnold13, Peter Lamprecht13, Florence Roufosse14, Ilaria Cavazzana1, Franco Franceschini1, Giacomo Emmi15, Paola Toniati1. | 1Rheumatology and Clinical Immunology Unit, ERN ReCONNET, ASST Spedali Civili of Brescia and University of Brescia, Italy, Brescia, Italy; 2Università Politecnica delle Marche and Azienda Ospedaliero Universitaria delle Marche, Ancona, Italy, Ancona, Italy; 3Section of Internal Medicine 'Guido Baccelli', DiMePRe-J, University of Bari 'Aldo Moro', Bari, Italy, Bari, Italy; 4Rheumatology Unit, IRCCS San Gerardo dei Tintori, Monza, Italy Monza Italy; 5Department of Biomedical Sciences, Humanitas University and Personalized Medicine, Asthma and Allergy IRCCS Humanitas, Milano, Italy; 6Division of Allergy and Clinical Immunology, ASST GOM Niguarda, Milan, Italy, Milano, Italy; 7Rheumatology Unit, Department of Medicine DIMED, University of Padua, Padova, Italy, Padova, Italy; 8University of Siena, Siena, Italy, Siena, Italy; 9Santa Chiara Hospital and University of Trento, Unit of Rheumatology, Trento, Italy Trento Italy; 10UCO Medicina Clinica, ASUGI, Cattinara Teaching Hospital, Trieste, Italy, Trieste, Italy; 11Division of Rheumatology, Department of Medicine DMED, University of Udine, Udine, Italy, Udine, Italy; 12University of Alberta, Edmonton, Alberta, Canada and Maastricht University, Maastricht, The Netherlands Maastricht The Netherlands; 13Department of Rheumatology and Clinical Immunology, University of Lübeck, Lübeck, Germany Lubeck Germany; 14Department of Internal Medicine, Hôpital Universitaire de Bruxelles - Erasme, Université Libre de Bruxelles, Belgium Brussels Belgium; 15Clinical Medicine and Clinical Immunology and Rheumatology Unit Cattinara University Hospital and University of Trieste, Trieste, Italy.
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PO:01:004 | Real-world retention of IL-17 inhibitors in psoriatic arthritis: impact of prior IL-17 exposure across multiple treatment lines in the “BIRRA” multicentre cohort Valentino Paci1, Alarico Ariani2, Eleonora Celletti3, Alberto Lo Gullo4, Camilla Mazzanti5, Valeria Nucera6, Natalia Mansueto7, Rosalba Caccavale8, Patrizia Del Medico9, Antonella Farina10, Palma Scolieri11, Cecilia Giampietro12, Olga Addimanda13, Riccardo Bixio14, Maddalena Larosa15, Viviana Ravagnani16, Federica Lumetti17, Aldo Biagio Molica Colella17, Elena Bravi17, Rosetta Vitetta17, Bernd Raffeiner17, Gilda Sandri18, Rosario Foti19, Simone Parisi20, Michele Maria Luchetti Gentiloni1, Gianluca Moroncini1. | 1Clinical Medicine, Department of Clinical and Molecular Sciences, Marche Polytechnic University, AOU delle Marche, Ancona, Italy; 2Internal Medicine and Rheumatology Unit, University Hospital of Parma, Parma, Italy; 3Rheumatology Unit, Clinica Medica Institute, Ospedale SS. Annunziata di Chieti, G.d'Annunzio University of Chieti, Chieti, Italy; 4Rheumatology Unit, ARNAS Garibaldi di Catania, Catania, Italy; 5Center for the Diagnosis and Therapy of Autoimmune Rheumagological Diseases, Ospedale Santa Rosa, ASL Viterbo Viterbo Italy; 6Rheumatology Outpatient Unit, ASL Novara, Novara, Italy; 7Ambulatori di Reumatologia ASL1 Liguria, Imperia Hospitall Imperia Italy; 8Department of Clinical, Anesthesiological and Cardiovascular Sciences, Sapienza University of Rome, Polo Pontino, Roma, Italy; 9Rheumatology outpatient clinic - Internal Medicine Unit, Civitanova Marche Hospital, Civitanova Marche, Italy; 10Internal Medicine Unit, Rheumatology outpatient clinic, Ospedale A. Murri di Fermo, Fermo, Italy; 11Department of Medical Specialties, Nuovo Regina Margherita Hospital, Rome, Roma, Italy; 12Rheumatology Outpatient Clinic, Azienda ULSS 6 Euganea, Padova, Padova, Italy; 13Rheumatology Unit, Azienda Unità Sanitaria Locale di Bologna -- Policlinico S.Orsola- AOU di Bologna, Bologna, Italy; 14Rheumatology Unit, IRCCS Sacro Cuore Don Calabria Hospital, Negrar di Valpolicella, Verona, Italy; 15Division of Rheumatology - Medical Specialties Department, Ospedale La Colletta-Azienda Sanitaria Locale 3, Genova, Italy; 16Rheumatology Unit, Santa Chiara Hospital APSS Trento Italy; 17BIRRA - BIologic Retention Rate in chronic Arthritis - study group, Parma, Italy; 18Rheumatology Unit, University of Modena and Reggio Emilia, Modena, Italy; 19Rheumatology Unit, Policlinico San Marco Hospital, Catania, Italy; 20Rheumatology Department, Azienda Ospedaliera Universitaria Città della Salute e della Scienza di Torino, Torino, Italy.
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PO:35:233 | Tocilizumab is associated with improved relapse-free survival in polymyalgia rheumatica: a multicentre retrospective study Milena Bond1, Giovanni Adami2, Marianna Tamussin3, Mario Frasca4, Sara Zandonella Callegher1, Marcello Govoni3, Maurizio Rossini2, Lorenzo Dagna4, Marco Matucci Cerinic4, Christian Dejaco1, Alessandro Tomelleri4 | 1Department of Rheumatology, Brunico Hospital ASAA-SABES, Teaching Hospital of the Paracelsius Medical University Bunico, Italy; 2Rheumatology Unit, University of Verona, Policlinico Borgo Roma Verona, Italy; 3Rheumatology Unit, Department of Medical Sciences, University of Ferrara and Azienda Ospedaliero-Universitaria S. Anna Ferrara, Italy; 4Unit of Immunology, Rheumatology, Allergy and Rare Diseases, IRCCS San Raffaele Hospital Milano, Italy
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PO:35:218 | Switching the dose of mepolizumab in patients with Eosinophilic Granulomatosis with Polyangiitis (EGPA): a European retrospective multicentre real-world study Edoardo Biancalana1, Irene Mattioli1, Emanuele Chiara2, Danilo Malandrino1, Maria Canfora1, Palmerini Miki1, Maria Paola Lisi1, Michela Gasparotto3, Paola Tomietto3, Maria Letizia Urban1, Giacomo Bagni1, Elena Silvestri1, Alessandra Bettiol3, Augusto Vaglio3, Giacomo Emmi2 | 1Department of Experimental and Clinical Medicine, University of Florence Firenze, Italy; 2Department of Medical, Surgery and Health Sciences, University of Trieste Trieste, Italy; 3Clinical Medicine and Rheumatology Unit, Cattinara University Hospital, Trieste, Trieste, Italy; 4Department of Biomedical, Experimental and Clinical Sciences Mario Serio, University of Florence Firenze, Italy
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