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PO:31:167 | Increased M2 pro-fibrotic marker expression in circulating monocytes and cultured monocyte-derived macrophages in systemic sclerosis patients with progressive interstitial lung disease Vanessa Smith1|2, Stefano Soldano3, Rosanna Campitiello3|5, Emanuele Gotelli3|4, Paola Montagna3, Elvis Hysa3|5, Tamara Vojinovic3|4, Carmen Pizzorni3|4, Sabrina Paolino3|4, Alberto Sulli3|4, Maurizio Cutolo3|4. | 1Department of Internal Medicine and Department of Rheumatology, Ghent University Hospital, Ghent, Belgium; 2Unit for Molecular Immunology and Inflammation, VIB Inflammation Research Centre, Ghent, Belgium; 3Laboratory of Experimental Rheumatology and Academic Division of Clinical Rheumatology, Department of Internal Medicine, Genova, Italy; 4IRCCS Ospedale Policlinico San Martino, Genova, Italy; 5Department of Experimental Medicine DIMES, University of Genova, Genova, Italy.
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PO:24:062 | Transcriptomic profile of salivary glands in patients with primary Sjögren’s syndrome and interstitial lung disease: implications for pathogenesis and risk stratification Elisa Pignatti1, Monia Maccaferri1, Alessandra Bisagni2, Alberto Cavazza2, Marco Sebastiani3|4, Luca Keller2, Luca Magnani5, Claudio Galluzzo2, Tommaso Fasano6, Lucia Nota6, Giulia Canu6, Andreina Manfredi1|2, Carlo Salvarani1|2 | 1Dipartimento Chimomo, Università di Modena e Reggio Emilia Modena; 2Struttura Complessa di Reumatologia, Azienda Unità Sanitaria Locale di Reggio Emilia-IRCCS; 3Dipartimento di Medicina e Chirurgia, Università degli Studi di Parma; 4Divisione di Reumatologia, AUSL di Piacenza; 5UOC Medicina Interna ind. reumatologico, AUSL di Bologna, Ospedale Maggiore, Bologna; 6Dipartimento Interaziendale ad Attività Integrata Medicina di Laboratorio ed Anatomia Patologica AUSL di Modena, Italy
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PO:30:152 | An altered immunometabolic profile characterizes B cells of patients with oligoarticular- and polyarticular- juvenile idiopathic arthritis Emiliano Marasco1, Angela Aquilani1, Rebecca Nicolai1, Maria Isabella Petrone1, Giusyda Tarantino1, Ivan Caiello1, Sabina Barresi2, Silvia Magni Manzoni1, Fabrizio De Benedetti1 | 1Unità di Reumatologia, Ospedale Pediatrico Bambino Gesù Roma, Italy; 2UO di Anatomia Patologica, Ospedale Pediatrico Bambino Gesù Roma, Italy
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PO:07:097 | CGRP and CALCRL localization supports the role of fibroblast-like synoviocytes in rheumatoid arthritis pain pathways Giada La Spina1, Cristina Garufi2, Mattia Caliste2, Martina Leopizzi3, Valeria Di Maio3, Cristiano Alessandri2, Fabrizio Conti2, Francesca Romana Spinelli2 | 1Sapienza University of Rome, Dipartimento di Medicina Molecolare, Roma, Italy; 2Sapienza University of Rome, Dipartimento di Scienze Cliniche Internistiche, Anestesiologiche e Cardiovascolari, Roma, Italy; 3Sapienza University of Rome, Dipartimento di Scienze e Biotecnologie Medico-Chirurgiche, Roma, Italy
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PO:19:281 | Mitochondrial dysfunction in Still’s disease: a preliminary analysis of mtDNA copy number and TFAM expression Ludovica Manisera1, Francesca Giansanti2, Andrea Latini3, Francesca Lotito4, Serena Colafrancesco5, Angelica Gattamelata6, Fabrizio Conti7, Cinzia Ciccacci8, Roberta Priori9 | 1|6|7|9La Sapienza, Roma; 2|3|4|8Unicamillus, Roma; 5Humanitas, Milano, Italy
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Association between COMMD1 gene polymorphism rs11125908 and rheumatoid arthritis in the Cuban population
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CO:07:5 | Enhanced fibroblast signatures in females with early rheumatoid arthritis highlights a potential basis for poorer treatment outcomes Benedetta Monosi1, James Perera2, Alessandra Nerviani2|3, Maria Sole Chimenti1, Felice Rivellese2|3, Costantino Pitzalis2|3|4. | 1Rheumatology, Allergology and Clinical Immunology, Department of Systems Medicine, University of Rome Tor Vergata, Rome, Italy; 2Centre for Experimental Medicine and Rheumatology, William Harvey Research Institute, Queen Mary University of London, London, UK; 3Barts Health NHS Trust and Barts Biomedical Research Centre, National Institute for Health and Care Research, London, UK; 4Department of Biomedical Sciences Humanitas University and IRCCS Humanitas Research Hospital, Milano, Italy
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