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• PO:02:025 | Real-World Comparative Effectiveness of Upadacitinib in Psoriatic Arthritis: Evaluation of Switching to Upadacitinib Versus Tumor Necrosis Factor Inhibitors or Interleukin-17 Inhibitors After First-Line Tumor Necrosis Factor Inhibitors Valentina Carlini¹, Philip Mease², William Tillett³, Xiaolan Ye⁴, Christopher Saffore⁴, Molly Edwards⁵, Isabel Truman⁵, Sophie Barlow⁵, Jayne Stigler⁴, Bhumik Parikh⁴, Daniel Aletaha⁶ | ¹Abbvie srl Roma, Italy; ²University of Washington School of Medicine Seattle, United States Minor Outlying Islands; ³Department of Rheumatology, Royal National Hospital for Rheumatic Diseases Bath, United Kingdom; ⁴Abbvie Inc. North Chicago, United States Minor Outlying Islands; ⁵Adelphi Real World Bollington, United Kingdom; ⁶Division of Rheumatology, Department of Medicine, Medical University of Vienna, Vienna, Austria

  Società Italiana di Reumatologia

  18-03-2026

  https://doi.org/10.4081/reumatismo.2025.2286

  76

• PO:02:021 | Sustained Improvements with Bimekizumab in Pain, Morning Stiffness, Fatigue, Physical Function and Health-Related Quality of Life in Patients with Axial Spondyloarthritis: 3-Year Results from Two Phase 3 Studies Victoria Navarro-Compán¹, Uta Kiltz^2|3, Philip J Mease⁴, Maureen Dubreuil⁵, Karl Gaffney⁶, Atul Deodhar⁷, Christine De La Loge⁸, Diana Voiniciuc⁹, Jason Coarse¹⁰, Ilaria Spadafora¹¹, Helena Marzo-Ortega¹² | ¹La Paz University Hospital, IdiPaz, Department of Rheumatology Madrid Spain; ²Ruhr-University Bochum Bochum Germany; ³Rheumazentrum Ruhrgebiet Herne, Germany; ⁴Department of Rheumatology, Swedish Medical Center and Providence St. Joseph Health and University of Washington Seattle, USA; ⁵Boston University School of Medicine, Department of Rheumatology Boston, USA; ⁶Norfolk and Norwich University Hospital NHS Trust, Department of Rheumatology Norfolk, United Kingdom; ⁷Oregon Health and Science University, Division of Arthritis and Rheumatic Diseases Portland, USA; ⁸UCB Brussels, Belgium; ⁹UCB Slough, United Kingdom; ¹⁰UCB Morrisville, USA; ¹¹UCB Milan, Italy; ¹²NIHR Leeds Biomedical Research Centre, University of Leeds Leeds, United Kingdom

  Società Italiana di Reumatologia

  18-03-2026

  https://doi.org/10.4081/reumatismo.2025.2284

  72

• PO:03:034 | Inhibition of Radiographic Progression with Bimekizumab Treatment Observed in bDMARD-Naïve Patients with Active Psoriatic Arthritis at 2 Years: Results from a Phase 3 Study and its Open-Label Extension Laura C Coates¹, M Elaine Husni², Mitsumasa Kishimoto³, Proton Rahman⁴, Philipp Sewerin⁵, Enrique R Soriano⁶, Barbara Ink⁷, Rajan Bajracharya⁷, Jason Coarse⁸, Philip J Mease⁹, Emanuela Mazzola¹⁰, Peter Nash¹¹ | ¹NDORMS, University of Oxford and Oxford Biomedical Research Centre, Oxford University Hospitals NHS Trust Oxford, United Kingdom; ²Department of Rheumatic and Immunologic Diseases, Cleveland Clinic Cleveland, USA; ³Department of Nephrology and Rheumatology, Kyorin University School of Medicine Tokyo, Japan; ⁴Division of Rheumatology, Craig L. Dobbin Genetics Research Centre, Memorial University of Newfoundland St. Johns, Canada; ⁵Rheumazentrum Ruhrgebiet, University Hospital of the Ruhr University Bochum Herne Germany; ⁶Hospital Italiano de Buenos Aires and University Institute Hospital Italiano de Buenos Aires Buenos Aires, Argentina; ⁷UCB Slough, United Kingdom; ⁸UCB Morrisville, USA; ⁹Department of Rheumatology, Providence-Swedish Medical Center and University of Washington Seattle, USA; ¹⁰UCB Milan, Italy; ¹¹School of Medicine, Griffith University, Brisbane, Australia

  Società Italiana di Reumatologia

  18-03-2026

  https://doi.org/10.4081/reumatismo.2025.2290

  123