Letters to the Editor Open access

Acute lung injury timely associated with the administration of tocilizumab

Authors

Published
29 January 2026
Section
Letters to the Editor

Abstract

Dear editor,
The interleukin-6 receptor inhibitor tocilizumab has been successfully used to treat various autoimmune diseases and has an acceptable, well-established safety profile...

References

  1. Kastrati K, Aletaha D, Burmester GR, Chwala E, Dejaco C, Dougados M, et al. A systematic literature review informing the consensus statement on efficacy and safety of pharmacological treatment with interleukin-6 pathway inhibition with biological DMARDs in immune-mediated inflammatory diseases. RMD Open 2022; 8: e002359. DOI: https://doi.org/10.1136/rmdopen-2022-002359
  2. Sugihara K, Wakiya R, Shimada H, Kato M, Kameda T, Nakashima S, et al. Interstitial lung disease occurring shortly after tocilizumab infusion in a patient with polyarticular juvenile idiopathic arthritis: a case report. Allergy Asthma Clin Immunol 2021; 17: 90. DOI: https://doi.org/10.1186/s13223-021-00594-7
  3. Sangüesa Gómez C, Flores Robles BJ, Jara Chinarro B, Espinosa Malpartida M, Barbadillo Mateos C. Acute pneumonitis in a patient with adult-onset disease after toclizumab treatment with good response to anakinra. Reumatol Clin 2016; 12: 345-7. DOI: https://doi.org/10.1016/j.reumae.2015.08.005
  4. Liu Y, Chen L. Impact of interleukin 6 levels on acute lung injury risk and disease severity in critically ill sepsis patients. World J Clin Cases 2024; 12: 5374-81. DOI: https://doi.org/10.12998/wjcc.v12.i23.5374

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