Coexistence of osteopoikilosis with seronegative spondyloarthritis and Raynaud’s phenomenon: first case report with evaluation of the nailfold capillary bed and literature review

Main Article Content

B. Ruaro
A. Sulli *
E. Alessandri
F. Ravera
M. Cutolo
(*) Corresponding Author:
A. Sulli | albertosulli@unige.it

Abstract

Osteopoikilosis (OPK) is a rare autosomal dominant bone disorder characterized by numerous hyperostotic areas that tend to localize in periarticular osseous regions. It is usually asymptomatic and is often diagnosed incidentally during X-rays. OPK may be an isolated finding or associated with other pathologies, e.g. skin manifestations, rheumatic and/or skeletal disorders. We report a literature review and, for the first time, the coexistence of OPK with seronegative spondyloarthritis and Raynaud’s phenomenon in a 48-year old female. To the best of our knowledge, this is the first case of OPK studied by videocapillaroscopy, demonstrating the absence of specific microvascular abnormalities of nailfold capillaries.

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Author Biographies

B. Ruaro, University of Genoa

Research Laboratory and Academic Unit of Clinical Rheumatology, Department of Internal Medicine

A. Sulli, University of Genoa

Research Laboratory and Academic Unit of Clinical Rheumatology, Department of Internal Medicine

E. Alessandri, University of Genoa

Research Laboratory and Academic Unit of Clinical Rheumatology, Department of Internal Medicine

F. Ravera, University of Genoa

Research Laboratory and Academic Unit of Clinical Rheumatology, Department of Internal Medicine

M. Cutolo, University of Genoa

Research Laboratory and Academic Unit of Clinical Rheumatology, Department of Internal Medicine