Cover Image

A case of false positive Troponin I in a patient affected by cryoglobulinemic vasculitis

M. Bellan, M. Pirisi, G. Bellomo, P.P. Sainaghi
  • M. Bellan
    Department of Translational Medicine, Università del Piemonte Orientale UPO, Novara; Division of Internal Medicine, Immunorheumatology Unit, AOU Maggiore della Carità, Novara, Italy | bellanmattia@yahoo.it
  • M. Pirisi
    Department of Translational Medicine, Università del Piemonte Orientale UPO, Novara; Division of Internal Medicine, Immunorheumatology Unit, AOU Maggiore della Carità, Novara; IRCAD (Interdisciplinary Reseach Center of Autoimmune Diseases), Novara, Italy
  • G. Bellomo
    Department of Health Sciences, Università del Piemonte Orientale UPO, Novara, Italy
  • P.P. Sainaghi
    Division of Internal Medicine, Immunorheumatology Unit, AOU Maggiore della Carità, Novara; IRCAD (Interdisciplinary Reseach Center of Autoimmune Diseases), Novara, Italy

Abstract

Troponin I (TnI) false positive results have been reported in patients affected by immune disorders. We report the case of a 74-year-old woman affected by cryoglobulinemic vasculitis, admitted to the Emergency Room because of a lipotimic episode. A marked elevation of TnI plasma concentration was confirmed in multiple determinations, despite the absence of symptoms or electrocardiogram findings suggesting myocardial infarction. TnI plasma concentration was reported normal after re-testing with a different commercial kit. A false TnI positivity should be considered in patients with immune disorders, especially if seropositive for rheumatoid factor, when the clinical context does not suggest myocardial infarction.

Keywords

Troponin I; vasculitis; cryoglobulinaemia.

Full Text:

PDF
Submitted: 2016-11-08 10:56:02
Published: 2017-05-22 16:02:13
Search for citations in Google Scholar
Related articles: Google Scholar
Abstract views:
381

Views:
PDF
166

Article Metrics

Metrics Loading ...

Metrics powered by PLOS ALM


Copyright (c) 2017 M. Bellan, M. Pirisi, G. Bellomo, P.P. Sainaghi

Creative Commons License
This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.
 
© PAGEPress 2008-2017     -     PAGEPress is a registered trademark property of PAGEPress srl, Italy.     -     VAT: IT02125780185