Case Reports Open access

A case of false positive Troponin I in a patient affected by cryoglobulinemic vasculitis

Authors

  • M. Bellan – articles in this journal Corresponding author Email Department of Translational Medicine, Università del Piemonte Orientale UPO, Novara; Division of Internal Medicine, Immunorheumatology Unit, AOU Maggiore della Carità, Novara, Italy.
  • M. Pirisi – articles in this journal Department of Translational Medicine, Università del Piemonte Orientale UPO, Novara; Division of Internal Medicine, Immunorheumatology Unit, AOU Maggiore della Carità, Novara; IRCAD (Interdisciplinary Reseach Center of Autoimmune Diseases), Novara, Italy.
  • G. Bellomo – articles in this journal Department of Health Sciences, Università del Piemonte Orientale UPO, Novara, Italy.
  • P.P. Sainaghi – articles in this journal Division of Internal Medicine, Immunorheumatology Unit, AOU Maggiore della Carità, Novara; IRCAD (Interdisciplinary Reseach Center of Autoimmune Diseases), Novara, Italy.
Published
22 May 2017
Section
Case Reports
DOI
10.4081/reumatismo.2017.941
Pages
40-42

Abstract

Troponin I (TnI) false positive results have been reported in patients affected by immune disorders. We report the case of a 74-year-old woman affected by cryoglobulinemic vasculitis, admitted to the Emergency Room because of a lipotimic episode. A marked elevation of TnI plasma concentration was confirmed in multiple determinations, despite the absence of symptoms or electrocardiogram findings suggesting myocardial infarction. TnI plasma concentration was reported normal after re-testing with a different commercial kit. A false TnI positivity should be considered in patients with immune disorders, especially if seropositive for rheumatoid factor, when the clinical context does not suggest myocardial infarction.

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