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PO:14:200 | Placental markers of angiogenesis in pregnant women with antiphospholipid syndrome: predictive role of SFLT-1, PLGF, and uterine artery doppler in preeclampsia Maria Bernadette Cilona1, Valentina Canti1, Martina Beschi2, Federica Pasi3, Serena Girardelli3, Mirko Pozzoni3, Maria Teresa Castiglioni3, Paolo Cavoretto3, Patrizia Rovere-Querini1|2 | 1Unit of Internal Medicine and Division of Immunology, Transplantation and Infectious diseases, IRCCS San Raffaele Hospital Milan, Italy; 2Vita-Salute San Raffaele University Milan, Italy; 3Department of Obstetrics and Gynecology, IRCCS San Raffaele Scientific Institute Milan, Italy
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CO:11:5 | Laboratory preliminary results from an open label, prospective, phase ii descriptive pilot trial of belimumab therapy for refractory and/or non criteria manifestations of antiphospholipid syndrome Alice Barinotti1, Massimo Radin1, Irene Cecchi1, Beatrice Ala1, Chiara Raymondi1, Elena Rubini1, Silvia G. Foddai1, Lois Ira Maniulit Capulong1, Alessio Conti1, Alessandro Morotti1, Dario Roccatello1, Roberta Fenoglio1, Savino Sciascia1. | 1Università di Torino, Italy.
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PO:14:199 | Preliminary data of a multicentric study on safety and efficacy of assisted reproductive techniques in pregnant women with systemic autoimmune diseases Valentina Canti1, Maria Bernadette Cilona1, Giuditta Gorgone1, Federica Pasi1, Antonia Calligaro2, Francesca Ruffilli3, Francesca Crisafulli6, Maria Tonello2, Eleonora Giacobbe4, Alba Chiara Pozzi6, Maria Chiara Gerardi4, Melissa Padovan3, Emanuele Bizzi5, Enrico Papaleo1, Beatrice Maranini3, Marcello Govoni3, Massimiliano Epis4, Angela Tincani6, Andrea Doria2, Patrizia Rovere Querini1 | 1IRCCS Ospedale San Raffaele and VitaSalute San Raffaele Milano, Italy; 2Rheumatology Unit, Departement of Medicine, University Hospital of Padua Padova, Italy; 3Rheumatology Unit, Azienda Ospedaliero Universitaria S. Anna Ferrara, Department of Medical Sciences, University of Fe Ferrara, Italy; 4ASST Grande Ospedale Metropolitano Niguarda Milano, Italy; 5Internal Medicine, Fatebenefratelli Hospital Milano, Italy; 6Rheumatology and Immunology Unit, ASST Spedali Civili Brescia e Università degli Studi di Brescia, Italy
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PO:15:221 | Proteins upregulated in thrombotic antiphospholipid syndrome link to platelet function in contrast with non-antiphospholipid-related thrombosis: insights from two systematic reviews Silvia Mancuso1, Claudia Ciancarella1, Luca Rapino1, Simona Truglia1, Cristiano Alessandri1, Fabrizio Conti1. | 1Dipartimento di Scienze Cliniche Internistiche, Anestesiologiche e Cardiovascolari - Rheumatology Unit, Sapienza Univers, Roma, Italy.
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PO:10:149 | Efficacy of anifrolumab in a case of systemic lupus erythematosus with pulmonary involvement Fabio Brandolino1, Giulia Pazzola1, Luca Ronzoni3, Andreina Teresa Manfredi1|2, Carlo Salvarani1|2 | 1SC Reumatologia, IRCCS Arcispedale Santa Maria Nuova, AUSL Reggio Emilia; 2Università di Modena e Reggio Emilia, Scuola di specializzazione in Reumatologia, Modena; 3SC Malattie dell'Apparato Respiratorio, IRCCS Arcispedale Santa Maria Nuova, AUSL Reggio Emilia, Italy
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PO:21:026 | Identifying patient profiles to personalize care and improve quality of life in italian EGPA patients Francesca Torracca1, Roberto Padoan2, Giacomo Emmi3|4, Lara Bernardi5, Maria Rosaria Mollo5, Omar Shalby5, Fabio Tedone6, Davide Cafiero6, Eugenia Durante1 | 1APACS APS ETS - Associazione Pazienti Sindrome di Churg Strauss EGPA Arosio, Italy; 2Rheumatology Unit, Department of Medicine DIMED, University of Padua, Italy; 3Department of Medical, Surgical and Health Sciences, University of Trieste, Italy; 4Clinical Medicine Rheumatology Unit, Cattinara University Hospital, Trieste, Italy; 5GlaxoSmithKline Medical Department Verona, Italy; 6Helaglobe SRL Firenze, Italy
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PO:12:187 | Maternal Hypertensive Disorders in Pregnant Women with Rheumatic Diseases and long-term Cardiovascular Outcomes: preliminary data of a single centre experience Margherita Rinaldi1, Paolo Semeraro1, Francesca Crisafulli1, Matteo Filippini2, Maria Grazia Lazzaroni1, Cecilia Nalli1, Liala Moschetti1, Marco Taglietti2, Chiara Loardi3, Rossana Orabona3, Francesca Ramazzotto3, Sonia Zatti3, Laura Andreoli1, Angela Tincani1, Micaela Fredi1, Ilaria Cavazzana1, Franco Franceschini1 | 1Department of Clinical and Experimental Sciences, University of Brescia, Italy; 2Rheumatology and Clinical Immunology, ASST Spedali Civili of Brescia, ERN-ReCONNET Center Brescia, Italy; 3Gynaecology and Obstetrics Unit ASST Spedali Civili di Brescia, Italy
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CO:11:4 | Unveiling frailty in active systemic lupus erythematosus in the modern era of rheumatology: first real-life use of the SLICC-FI in a cohort diagnosed after 2000 Angela Elia1, Dina Zucchi2, Michele Moretti1, Elena Elefante2, Chiara Cardelli1, Linda Carli2, Viola Signorini2, Chiara Stagnaro2, Chiara Tani1, Marta Mosca1. | 1U.O. di Reumatologia, Dipartimento di Medicina Clinica e Sperimentale, Università di Pisa; 2U.O Reumatologia, Azienza Ospedaliero Universitaria Pisana, Pisa, Italy
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PO:16:225 | Belimumab in refractory and/or non-criteria manifestations of antiphospholipid syndrome: ad interim analysis on Quality-of-Life changes from the BLAST trial Alessio Conti1, Lois Ira Capulong1, Irene Cecchi1, Elena Rubini1, Chiara Bova1, Massimo Radin1, Alice Barinotti1, Beatrice Ala1, Silvia Grazietta Foddai1, Daniela Rossi1, Roberta Fenoglio1, Savino Sciascia1 | 1Centro di Eccellenza Universitario per le Malattie Nefrologiche, Reumatologiche e Rare, S.G.Bosco -ASL Città di Torino, Italy
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CO:11:2 | Systemic lupus erythematosus with major neuropsychiatric involvement treated with anifrolumab: literature review and a case report Giulia Rizzo1, Fabio Congiu1, Elisabetta Chessa2, Marta Paola Pireddu1, Elena Ragusa1, Alessandra Oliva1, Marianna Salis1, Alberto Cauli1|2, Matteo Piga1|2 | 1SC Reumatologia, Dipartimento di Scienze Mediche e Salute Pubblica, Università di Cagliari Italy; 2SC Reumatologia, AOU Cagliari Italy
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PO:14:205 | Primary antiphospholipid antibody syndrome: association between new classification criteria manifestations and a higher-risk disease phenotype Sara Ferrigno1, Vittorio Forte2, Marco Panetta1, Sergio Lisena1, Giorgia Ranucci2, Luigi De Marco1, Elisabetta Greco1, Alberto Bergamini1, Maria Sole Chimenti1, Paola Conigliaro1. | 1Rheumatology, allergology and clinical immunology, Department of Systems Medicine, University of Rome Tor Vergata, Rome, Italy; 2Hematology, Department of Biomedicine and Prevention, University of Rome Tor Vergata, Rome, Italy.
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