Biclonal gammopathy of undetermined significance in a patient with systemic lupus erythematosus and antiphospholipid syndrome

Submitted: 17 May 2021
Accepted: 11 November 2021
Published: 7 February 2022
Abstract Views: 5586
PDF: 565
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The case of a patient suffering from systemic lupus erythematosus with associated antiphospholipid antibody syndrome is described. In this patient, on protein electrophoresis, two monoclonal immunoglobulin G λ and k peaks were seen, defining a condition of biclonal gammopathy of undetermined significance (BGUS). This condition is extremely rare, especially in chronic inflammatory rheumatic diseases. The criteria of a BGUS are defined. We also underline how this condition can be the expression of a concomitant unrecognized cancer, a possible amyloidosis or an infectious process.

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Citations

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How to Cite

Bruzzese, V., Scolieri, P., & Pepe, J. (2022). Biclonal gammopathy of undetermined significance in a patient with systemic lupus erythematosus and antiphospholipid syndrome. Reumatismo, 73(4). https://doi.org/10.4081/reumatismo.2021.1431

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