Case Reports
27 May 2013
Vol. 65 No. 2 (2013)
https://doi.org/10.4081/reumatismo.2013.86

Seronegative spondyloarthritis and Darier’s disease: more than a casual association?

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Seronegative spondyloarthrits, Darier’ disease, Arthritis.
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Authors

C. Cosso
claudio.cosso86@gmail.com
Academic Unit of Clinical Rheumatology and Research Laboratory, Dipartimento di Medicina Interna (DI.M.I.), Italy.
F. Rongioletti
Section of Dermatology, DISSAL, Unity of Pathology, University of Genoa, Genoa, Italy.
G. Zampogna
Academic Unit of Clinical Rheumatology and Research Laboratory, Dipartimento di Medicina Interna (DI.M.I.), Italy.
D. Camellino
Academic Unit of Clinical Rheumatology and Research Laboratory, Dipartimento di Medicina Interna (DI.M.I.), Italy.
M. Cutolo
Academic Unit of Clinical Rheumatology and Research Laboratory, Dipartimento di Medicina Interna (DI.M.I.), Italy.
M. A. Cimmino
Academic Unit of Clinical Rheumatology and Research Laboratory, Dipartimento di Medicina Interna (DI.M.I.), Italy.
A 46-year old man, affected by Darier’s disease (DD), was seen because of right hand pain, later extended to shoulders and ankles. Physical examination showed swelling and tenderness of the wrist, metacarpophalangeal and metatarsophalangeal joints, of the right Achilles tendon’s enthesis and of the left knee, with psoriatic-like lesions of the scalp. A diagnosis of seronegative spondyloarthritis, supported by HLA-B27 positivity and by the magnetic resonance imaging fi nding of hand synovitis and unilateral sacro-iliitis, was made. The correlation between DD, spondyloarthritis and psoriasis has been already anecdotally reported. Further observations may clarify if this association is more than casual.

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Seronegative spondyloarthritis and Darier’s disease: more than a casual association?. (2013). Reumatismo, 65(2), 86-89. https://doi.org/10.4081/reumatismo.2013.86

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