Possible role of Hsp70 in autoantigens shuttling to dermo-epidermal junction in systemic lupus erythematosus

Abstract Views: 763
PDF: 799
Publisher's note
All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher.

Authors

Under stress cells and tissues perform a series of physiologic adjustments, including the heat shock protein production (Hsp), these proteins play a role as molecular chaperons, they are divided in five main families: Hsp27, Hsp 60, Hsp70, Hsp90 and Hsp110 (1). Hsp are constitutively induced or expressed to support the correct folding of novel proteins or to refold damaged proteins (2). Hsp70 is the most representative member of Hsp family. It is largely distributed in the majority of eukaryotic cell compartments and interact with the cytoskeleton during translocation of proteins across membranes (3).

Dimensions

Altmetric

PlumX Metrics

Downloads

Download data is not yet available.

Citations

How to Cite

Villalobos-Hurtado, R., Sánchez-Rogriguez, S., Avalos-Díaz, E., & Herrera-Esparza, R. (2003). Possible role of Hsp70 in autoantigens shuttling to dermo-epidermal junction in systemic lupus erythematosus. Reumatismo, 55(3), 155–158. https://doi.org/10.4081/reumatismo.2003.155