Reviews
Vol. 69 No. 3 (2017)
https://doi.org/10.4081/reumatismo.2017.1032

The clinical spectrum of primary Sjögren’s syndrome: beyond exocrine glands

Publisher's note
All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher.
Received: 20 June 2017
Published: 21 September 2017
4771
Views
1971
Downloads
Sjögren’s syndrome, Extra-glandular manifestations, Cardiovascular risk.
Rheumatology

Authors

M.C. Leone
Rheumatology Unit, Department of Medicine, University of Perugia, Italy.
A. Alunno
Rheumatology Unit, Department of Medicine, University of Perugia, Italy.
G. Cafaro
Rheumatology Unit, Department of Medicine, University of Perugia, Italy.
V. Valentini
Rheumatology Unit, Department of Medicine, University of Perugia, Italy.
E. Marcucci
Rheumatology Unit, Department of Medicine, University of Perugia, Italy.
E. Bartoloni
Rheumatology Unit, Department of Medicine, University of Perugia, Italy.
R. Gerli
roberto.gerli@unipg.it
Rheumatology Unit, Department of Medicine, University of Perugia, Italy.
Although primary Sjögren’s syndrome (pSS) is a mild indolent chronic disease mainly characterized by mucosal dryness in the majority of cases, a consistent subgroup of patients display extra-glandular manifestations. Virtually any organs and systems can be affected, leading to a more serious disease prognosis. Therefore, the prompt identification of patients at higher risk of extra-glandular manifestations is necessary to start a thorough follow up and an aggressive treatment. The aim of this review article is to provide an overview of epidemiological, clinical and serological features of extra-glandular manifestations in pSS as well as current knowledge about putative biomarkers useful in clinical practice.

Downloads

Download data is not yet available.

How to Cite



1.
The clinical spectrum of primary Sjögren’s syndrome: beyond exocrine glands. Reumatismo [Internet]. 2017 Sep. 21 [cited 2026 Aug. 30];69(3):93-100. Available from: https://www.reumatismo.org/reuma/article/view/1032

PAGEPress has chosen to apply the Creative Commons Attribution NonCommercial 4.0 International License (CC BY-NC 4.0) to all manuscripts to be published.