Cardiovascular and renal effects of hyperuricaemia and gout

  • F. Viazzi | francesca.viazzi@unige.it University of Genoa, Italy.
  • G. Leoncini University of Genoa, Italy.
  • R. Pontremoli University of Genoa, Italy.

Abstract

A number of epidemiological studies have reported an association between serum uric acid levels and a wide variety of high-risk conditions including hypertension, insulin resistance, and kidney and cerebro-cardiovascular disease. All things considered, serum uric acid may induce cardiovascular and kidney events both directly and indirectly by promoting other well-known mechanisms of damage. While asymptomatic hyperuricemia is currently not considered to be an indication for urate lowering therapy, there is growing evidence indicating a linear relationship between pharmacological reduction in serum uric acid and incidence of cardiovascular and renal events.

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Author Biographies

F. Viazzi, University of Genoa
Department of Cardionephrology
G. Leoncini, University of Genoa
Department of Cardionephrology
R. Pontremoli, University of Genoa
Department of Cardionephrology
Keywords:
hyperuricaemia, gout, cv risk, kidney, organ damage.
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How to Cite
Viazzi, F., Leoncini, G., & Pontremoli, R. (1). Cardiovascular and renal effects of hyperuricaemia and gout. Reumatismo, 63(4), 253-262. https://doi.org/10.4081/reumatismo.2011.253