Nailfold videocapillaroscopy in antisynthetase syndrome

  • G. Cassone | cassonegiu@gmail.com Rheumatology Unit, University of Modena and Reggio Emilia, Modena; Clinical and Experimental Medicine PhD Program, University of Modena and Reggio Emilia, Modena; Rheumatology Unit, IRCCS Arcispedale Santa Maria Nuova, Azienda Unità Sanitaria Locale-IRCCS di Reggio Emilia, Reggio Emilia, Italy.
  • M. Sebastiani Rheumatology Unit, University of Modena and Reggio Emilia, Modena, Italy.
  • L. Cavagna Division of Rheumatology, University and IRCCS Policlinico S. Matteo Foudation, Pavia, Italy.
  • K. Triantafyllias ACURA Rheumatology Clinics, Bad Kreuznach, Germany.
  • V. Codullo Division of Rheumatology, University and IRCCS Policlinico S. Matteo Foudation, Pavia, Italy.
  • C. Salvarani Rheumatology Unit, University of Modena and Reggio Emilia, Modena; Rheumatology Unit, IRCCS Arcispedale Santa Maria Nuova, Azienda Unità Sanitaria Locale-IRCCS di Reggio Emilia, Reggio Emilia, Italy.
  • A. Manfredi Rheumatology Unit, University of Modena and Reggio Emilia, Modena, Italy.

Abstract

A 57-year-old woman with a diagnosis of antisynthetase syndrome (ASSD) underwent a nailfold videocapillaroscopy (NVC) showing a scleroderma pattern. Alterations in capillary morphology have been reported in adults with inflammatory myositis (IM) but only recently have the differences in NVC findings between these two diseases been established. ASSD is currently classified as a subset of IM, for which reason only a few studies in literature evaluate its specific hallmarks, showing nonspecific features of NVC in patients with polymyositis and dermatomyositis (DM) and antisynthetase antibodies. To our knowledge, this is the first description of ASSD capillaroscopy features, and the first report of NVC in ASSD with evidence of scleroderma pattern. Further studies are needed to define clearly frequency, typical features, and possible correlation with clinical and serological data of NVC changes in ASSD, differences between microangiopathy in ASSD and systemic sclerosis or DM.

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Published
2018-12-20
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Section
Case Reports
Keywords:
Nailfold videocapillaroscopy, Inflammatory myositis, Antisynthetase syndrome, Raynaud’s phenomenon.
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How to Cite
Cassone, G., Sebastiani, M., Cavagna, L., Triantafyllias, K., Codullo, V., Salvarani, C., & Manfredi, A. (2018). Nailfold videocapillaroscopy in antisynthetase syndrome. Reumatismo, 70(4), 257-258. https://doi.org/10.4081/reumatismo.2018.1105