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• PO:06:094 | Exploring the relationship between inflammation and collagen deposition in synovial tissue and clinical outcomes in active arthritis: insights from a monocentric pilot study Dario Bruno¹, Barbara Tolusso¹, Daniela Renna¹, Mohamed Hegazi², Fabio Pasqualini², Marta Caprioli¹, Giacomo Maria Guidelli¹, Tommaso Hubert³, Nicoletta Luciano^1|3, Marzia Monferini³, Natasa Isailovic³, Fabio Grizzi^2|3, Salvatorelorenzo Renne³, Costantino Pitzalis^1|3|4, Elisa Gremese^1|3. | ¹Rheumatology and Clinical Immunology, IRCCS Humanitas Research Hospital, Rozzano (MI); ²Department of Immunology and Inflammation, IRCCS Humanitas Research Hospital, Milano; ³Department of Biomedical Sciences, Humanitas University, Rozzano (MI), Italy; ⁴Centre for Experimental Medicine and Rheumatology, Queen Mary University of London, London, UK

  Società Italiana di Reumatologia

  25-11-2025

  https://doi.org/10.4081/reumatismo.2025.2019

  237

• CO:07:5 | Enhanced fibroblast signatures in females with early rheumatoid arthritis highlights a potential basis for poorer treatment outcomes Benedetta Monosi¹, James Perera², Alessandra Nerviani^2|3, Maria Sole Chimenti¹, Felice Rivellese^2|3, Costantino Pitzalis^2|3|4. | ¹Rheumatology, Allergology and Clinical Immunology, Department of Systems Medicine, University of Rome Tor Vergata, Rome, Italy; ²Centre for Experimental Medicine and Rheumatology, William Harvey Research Institute, Queen Mary University of London, London, UK; ³Barts Health NHS Trust and Barts Biomedical Research Centre, National Institute for Health and Care Research, London, UK; ⁴Department of Biomedical Sciences Humanitas University and IRCCS Humanitas Research Hospital, Milano, Italy

  Società Italiana di Reumatologia

  25-11-2025

  https://doi.org/10.4081/reumatismo.2025.1980

  3954