Radiological vignette
Vol. 68 No. 2 (2016)
https://doi.org/10.4081/reumatismo.2016.889

Critical finger ischemia and myocardial fibrosis development after sudden interruption of sildenafil treatment in a systemic sclerosis patient

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Received: 5 May 2016
Accepted: 1 August 2016
Published: 9 September 2016
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Systemic sclerosis, critical ischemia, phosphodiesterase 5 inhibitors, cardiac magnetic resonance imaging, myocardial fibrosis.

Authors

C. Bruni
cosimobruni85@gmail.com
Department of Experimental and Clinical Medicine, Division of Rheumatology, University of Firenze, Italy.
S. Bellando-Randone
Department of Experimental and Clinical Medicine, Division of Rheumatology, University of Firenze, Italy.
L. Gargani
Institute of Clinical Physiology, National Council of Research, Pisa, Italy.
E. Picano
Institute of Clinical Physiology, National Council of Research, Pisa, Italy.
A. Pingitore
Institute of Clinical Physiology, National Council of Research, Pisa, Italy.
M. Matucci-Cerinic
Department of Experimental and Clinical Medicine, Division of Rheumatology, University of Firenze, Italy.
S. Guiducci
Department of Experimental and Clinical Medicine, Division of Rheumatology, University of Firenze, Italy.
Systemic sclerosis (SSc) is a connective tissue disease frequently associated with Raynaud’s Phenomenon (RP). Among possible pharmacological treatments, phosphodiesterase 5 inhibitors are considered in cases of severe non -responsive RP. We present the case of a male SSc patient wh presented with critical finger ischemia and concomitant appearance of myocardial fibrosis after sudden interruption of sildenafil treatment.

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1.
Critical finger ischemia and myocardial fibrosis development after sudden interruption of sildenafil treatment in a systemic sclerosis patient. Reumatismo [Internet]. 2016 Sep. 9 [cited 2025 Nov. 21];68(2):109-11. Available from: https://www.reumatismo.org/reuma/article/view/889