TY - JOUR AU - Ciompi, M.L. AU - Amoresano, C. AU - Balzarini, P. AU - Bazzichi, L.M. AU - Broggini, M. AU - Buratti, L. AU - Calcagnile, F. AU - Ciocci, A. AU - Ferri, S. AU - Fichera, C. AU - Fumagalli, M. AU - Muratore, M. AU - Nitti, F. AU - Peruz, G. AU - Romagnoni, G. PY - 2002/09/30 Y2 - 2024/03/29 TI - Sodium-gold thyosolphatum therapy: an open, viewed, multicenter trial in rheumatoid arthritis patients followed for two years JF - Reumatismo JA - Reumatismo VL - 54 IS - 3 SE - Articles DO - 10.4081/reumatismo.2002.251 UR - https://www.reumatismo.org/reuma/article/view/reumatismo.2002.251 SP - 251-256 AB - Objective: To evaluate if parenteral gold-therapy with Sodium-Gold Thyosolphatum is effective and safe for the treatment of rheumatoid arthritis we began an open, multicenter trial. Methods: 126 rheumatoid arthritis patients were treated with Sodium-Gold Thyosolphatum for two years. Efficacy, quality of life, progression of joint damage, inflammatory parameters and side effects were evaluated. Results: Gold salts reduced joint inflammation and improved subjective and objective symptoms, quality of life and activity of illness within 6 months. Side effects appeared in 13,8% of all cases and regressed, promptly, when gold therapy stopped. The poor efficacy caused the interruption and the change from the gold therapy to others diseasemodifying anti-rheumatic drugs (DMRDs) in 17,8 % of the patients. Conclusions: The follow-up showed Sodium-Gold Thyosolphatum was effective in Rheumatoid Arthritis and the survival in therapy was of 77,8% to one year and of 68,4% to two years. ER -