Metabolism of crystals within the joint

Main Article Content

F. Oliviero
A. Scanu
L. Punzi *
(*) Corresponding Author:
L. Punzi | punzireu@unipd.it

Abstract

Monosodium urate (MSU), calcium pyrophosphate dihydrate (CPPD) and basic calcium phosphate (BCP) crystals deposit in joints and surrounding tissues causing acute inflammation and chronic cartilage damage. A number of endogenous substances and physicochemical conditions affect their precipitation, growth and even dissolution, regulating their metabolism and inflammatory activity. We review how MSU and calcium crystals form within the joints and the various factor which regulate their formation.

Downloads month by month

Downloads

Download data is not yet available.

Article Details

Author Biographies

F. Oliviero, University of Padova

Rheumatology Unit, Department of Clinical and Experimental Medicine

A. Scanu, University of Padova

Rheumatology Unit, Department of Clinical and Experimental Medicine

L. Punzi, University of Padova

Rheumatology Unit, Department of Clinical and Experimental Medicine