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12 July 2025
Vol. 63 No. 4 (2011): Special issue • Microcrystalline Arthritis
https://doi.org/10.4081/reumatismo.2011.221

Metabolism of crystals within the joint

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monosodium urate, pyrophosphate, basic calcium phosphate, crystals, metabolism
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Authors

F. Oliviero
University of Padova, Italy.
A. Scanu
University of Padova, Italy.
L. Punzi
punzireu@unipd.it
University of Padova, Italy.
Monosodium urate (MSU), calcium pyrophosphate dihydrate (CPPD) and basic calcium phosphate (BCP) crystals deposit in joints and surrounding tissues causing acute inflammation and chronic cartilage damage. A number of endogenous substances and physicochemical conditions affect their precipitation, growth and even dissolution, regulating their metabolism and inflammatory activity. We review how MSU and calcium crystals form within the joints and the various factor which regulate their formation.

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F. Oliviero, University of Padova
Rheumatology Unit, Department of Clinical and Experimental Medicine
A. Scanu, University of Padova
Rheumatology Unit, Department of Clinical and Experimental Medicine
L. Punzi, University of Padova
Rheumatology Unit, Department of Clinical and Experimental Medicine

How to Cite



Metabolism of crystals within the joint. (2011). Reumatismo, 63(4), 221-229. https://doi.org/10.4081/reumatismo.2011.221

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