GENETICS OF PSORIASIS AND PSORIATIC ARTHRITIS
AbstractPsoriasis and psoriatic arthritis are linked diseases characterised by (distinct ?) immune-mediated pathogenetic mechanisms and by a genetic background interacting with environmental factors. Some candidate susceptibility genes have been studied extensively; they include HLA genes, genes within the HLA region and genes outside the HLA region; among them corneodesmosin and other genes of PSORS1 region, MICA and TNF-a polymorphisms. The main findings in the literature are discussed. Key words: Genetics, psosriasis, psoriatic arthritis
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Copyright (c) 1970 A. Mathieu, A. Cauli, A. Vacca, A. Mameli, G. Passiu, G. Porru, M. Piga, V. Ibba, V. Mura, S. Anna
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