GENETICS OF PSORIASIS AND PSORIATIC ARTHRITIS

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Psoriasis and psoriatic arthritis are linked diseases characterised by (distinct ?) immune-mediated pathogenetic mechanisms and by a genetic background interacting with environmental factors. Some candidate susceptibility genes have been studied extensively; they include HLA genes, genes within the HLA region and genes outside the HLA region; among them corneodesmosin and other genes of PSORS1 region, MICA and TNF-a polymorphisms. The main findings in the literature are discussed. Key words: Genetics, psosriasis, psoriatic arthritis

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Mathieu, A., Cauli, A., Vacca, A., Mameli, A., Passiu, G., Porru, G., Piga, M., Ibba, V., Mura, V., & Anna, S. (2007). GENETICS OF PSORIASIS AND PSORIATIC ARTHRITIS. Reumatismo, 59(s1), 25–27. https://doi.org/10.4081/reumatismo.2007.1s.25